Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (110)
- Children (97)
- Oxidative stress (90)
- Inflammation (65)
- Rat (62)
-
- Mortality (59)
- Treatment (57)
- Turkey (57)
- Breast cancer (51)
- Prognosis (51)
- Pregnancy (49)
- Apoptosis (47)
- Prevalence (47)
- Magnetic resonance imaging (46)
- Obesity (46)
- Diabetes mellitus (37)
- Quality of life (36)
- Risk factors (36)
- Diagnosis (34)
- Nitric oxide (32)
- Ultrasonography (32)
- Rheumatoid arthritis (31)
- Epidemiology (30)
- Asthma (29)
- Hypertension (29)
- Reliability (29)
- Child (28)
- Validity (28)
- Depression (26)
- Diabetes (26)
- Publication Year
Articles 2821 - 2850 of 4871
Full-Text Articles in Medicine and Health Sciences
Prohepcidin In Maternal Circulation: Is It Related To Spontaneous Preterm Labor?, Yüksel Onaran, Esra Aktepe Keski̇n, Zehra Candan İltemi̇r Duvan, Serap Aynur Si̇mavli, Cemi̇le Koca, Hasan Kafali, Ni̇lgün Turhan
Prohepcidin In Maternal Circulation: Is It Related To Spontaneous Preterm Labor?, Yüksel Onaran, Esra Aktepe Keski̇n, Zehra Candan İltemi̇r Duvan, Serap Aynur Si̇mavli, Cemi̇le Koca, Hasan Kafali, Ni̇lgün Turhan
Turkish Journal of Medical Sciences
To investigate whether spontaneous preterm labor (PTL) with intact membranes is associated with changes in maternal serum prohepcidin concentrations. Materials and methods: The study consisted of patients with spontaneous PTL with intact membranes (n = 25), a control group of healthy pregnant women between the 24th and 37th gestational weeks (n = 22), and uncomplicated term pregnancies in spontaneous labor (n = 19). Blood samples were collected from patients at the time of clinical diagnosis. Levels of prohepcidin, hemoglobin, serum ferritin, serum iron, unsaturated iron binding capacity, total iron binding capacity, transferrin and transferrin saturation, C reactive protein, and interleukin-6 …
The Diagnostic Efficiency Of Ct And Mri In Ileosigmoid Knotting, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bülent Aydinli, Gürkan Öztürk, Şükrü Arslan, Ercan Korkut, Metehan Gümüş, Abdullah Böyük
The Diagnostic Efficiency Of Ct And Mri In Ileosigmoid Knotting, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bülent Aydinli, Gürkan Öztürk, Şükrü Arslan, Ercan Korkut, Metehan Gümüş, Abdullah Böyük
Turkish Journal of Medical Sciences
No abstract provided.
Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k
Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k
Turkish Journal of Medical Sciences
For surgical treatment of unstable distal radius fractures, fixed-angled locking volar plate fixation is becoming popular nowadays because of some advantages over other surgical techniques. In this article, we discuss the fitting of fixed-angle locking volar plates to the distal radius in relation to the changes in the distal radial angles. Materials and methods: First, we took conventional radiography images of 18 dried radii and later we measured the palmar subchondral angle, dorsal subchondral angle, mid-subchondral angle, and palmar cortical angle using lateral radiography. Results: According to the measurements, the volar subchondral angles (alpha) ranged from 10.2° to 28.1°, the …
Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r
Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r
Turkish Journal of Medical Sciences
To analyze the phenolic composition of the Cimin grape, which is 1 of 2 grape varieties with a protected geographical indication in Turkey and is used locally to treat the symptoms of some disorders such as impotence and cardiovascular diseases, and to investigate its antioxidant potency against oxidant mediators in the models of intra- and extracellular surroundings. Materials and methods: Cimin grape samples were classified into 5 groups according to the grape's tissues and the extraction solvents used. Free radical scavenging (DPPH) and antilipid peroxidation product [thiobarbituric acid reactive substance (TBARS) and conjugated diene (CD)] levels of the grape tissues …
Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural
Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural
Turkish Journal of Medical Sciences
Hyperhidrosis is defined as excessive sweating beyond the physiologic needs of a person. Palmar hyperhidrosis in the adolescent period may have an impact on school work and may cause psychological problems. In this study we aim to increase awareness of this disregarded problem. Materials and methods: We explicated the early outcomes of 7 consecutive adolescents, where single port video-assisted thoracoscopic sympathectomy was performed for primary palmar hyperhidrosis. Patients were evaluated for symptom resolution, which was defined as complete dryness, patient satisfaction, operative complications, and compensatory sweating. Results: In total 13 thoracoscopic procedures were done in 7 adolescents, consisting of 4 …
Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k
Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k
Turkish Journal of Medical Sciences
To evaluate the role of perioperative freezing in the management of surgical procedures in patients with malignant renal masses. Materials and methods: The study group consisted of 17 patients diagnosed with renal masses who underwent nephron-sparing surgery. The group included 5 females and 12 males aged from 44 to 68 years (mean = 54.6). The mean mass size was 5.5 cm. Mass locations were as follows: 9 were in the lower pole, 4 were in the mid-pole, and 6 were in the upper pole. Perioperative freezing was not carried out. The patients were followed-up in a period ranging from 3 …
Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp
Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp
Turkish Journal of Medical Sciences
To evaluate whether caffeic acid phenethyl ester (CAPE), a flavonoid-like natural compound plentifully found in beeswax, has a protective effect on diazinon-induced serum cholinesterase (ChE) inhibition in rats. Materials and methods: Animals were divided into 4 groups. The first animal group was not treated with any substance. The second animal group was orally given a 200 mg/kg body weight (bw) sublethal dose of diazinon. The third animal group was injected intraperitoneally with 2.84 mg (10 µmol)/kg bw of CAPE 1 day prior to administration of 200 mg/kg bw of diazinon orally. The fourth animal group was intraperitoneally injected with 2.84 …
Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu
Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu
Turkish Journal of Medical Sciences
This study was designed to investigate the function of outer hair cells and medial olivocochlear efferents in type II diabetes mellitus (DM). Materials and methods: There were 50 patients with type II DM and 51 age- and sex-matched healthy controls included in the study. Both groups were compared in terms of transient evoked otoacoustic emissions (TEOAEs), distortion product otoacoustic emissions (DPOAEs), and contralateral suppression of TEOAE. Results: Pure tone thresholds of the patients with type II DM were significantly higher than in the controls (P < 0.05). The TEOAE amplitudes at 1 kHz and at 1.5, 2, 3, 4, and 6 kHz signal-to-noise ratio amplitudes on DPOAE testing were significantly lower in the patients than controls (P < 0.05). There was no significant difference between the type II DM and control groups regarding contralateral suppression test results of TEOAEs. Conclusion: Type II DM seems to impact the auditory system at the cochlear level by affecting the functions of outer hair cells, and it results in elevation of the thresholds on audiometry and a decrease in the amplitudes of otoacoustic emissions.
Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak
Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak
Turkish Journal of Medical Sciences
This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning …
Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
To analyze patients with Castleman disease who were diagnosed by surgery. Materials and methods: We retrospectively investigated the postoperative pathological records of operations performed between January 1992 and December 2012 in our hospital. Files of 19 patients with the diagnosis of Castleman disease were analyzed. Results: There were 13 male and 6 female patients with a mean age of 40.1 ± 11.4 (range: 20-57) years. Fifteen thoracotomies and 3 video-assisted thoracoscopies, 12 on the right side and 6 on the left side, and 1 mediastinoscopy were performed. Biopsies and mass excisions were performed in 2 and 17 cases, respectively. Histopathological …
Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇
Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇
Turkish Journal of Medical Sciences
To define the frequency of familial Mediterranean fever gene (MEFV) mutations in ankylosing spondylitis (AS) and describe different clinical aspects of MEFV mutation carrier and noncarrier AS patients. Materials and methods: In 112 AS patients, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores were calculated. The frequencies of 12 different MEFV mutations were studied by multiplex polymerase chain reaction/reverse hybridization method and were compared to those of previously studied healthy controls for 5 common MEFV mutations. Results: MEFV mutations were identified in 46 of 224 (20%) alleles and in 39 (35%) of AS …
Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay
Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay
Turkish Journal of Medical Sciences
To evaluate the effectiveness of the addition of epirubicin to conventional chemotherapy as a first-line therapy for stage III–IV epithelial ovarian cancer. Materials and methods: A total of 132 patients who had undergone primary cytoreductive surgery between January 1998 and March 2003 were enrolled in the study. Twenty-four cases were excluded. Out of the remaining 108 subjects, 35 received epirubicin/paclitaxel/carboplatin (Group EPC) and 73 were treated with paclitaxel/platinum (cisplatin or carboplatin) (Group PC). Results: The median follow-up period was 66.5 months. The clinical complete response was 94% in the EPC group and 97% in the PC group. The recurrence rate …
Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu
Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu
Turkish Journal of Medical Sciences
To carry out comparison and correlation analyses of the intervertebral disc (IVD) and vertebral body (VB) volumes in magnetic resonance (MR) images of patients with degenerated and nondegenerated lumbar discs. Materials and methods: MR images were examined retrospectively in 93 patients. Lumbar VB and IVD volumes in T1-T2 weighted sagittal MR images were calculated via the Cavalieri method, a stereological method. Volumetric changes in degenerated and nondegenerated discs were compared. Results: The percentages of degenerated IVDs were 12.9%, 12.9%, 28%, 50.5%, and 52% in discs from levels L1 to L5, respectively. There were no differences in VB volumes between the …
The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan
The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan
Turkish Journal of Medical Sciences
To evaluate the prevalence of nocturia among different degrees of obstructive sleep apnea (OSA) and its association with various clinical conditions. Materials and methods: In 730 OSA patients, the prevalence and frequency of nocturia was determined, and the association of nocturia with clinical and laboratory variables such as the apnea-hypopnea index (AHI), apnea duration, and minimum oxygen saturation and clinical conditions such as diabetes mellitus, coronary heart disease, and chronic obstructive pulmonary disease (COPD) was determined. Results: The overall prevalence of nocturia (>=2 wakes/night) was 50.9%. Prevalences of nocturia in simple snoring and mild, moderate, and severe OSA patients …
New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu
New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu
Turkish Journal of Medical Sciences
To conduct a histopathological evaluation of the effects of Ankaferd Blood Stopper (ABS) on healing wounds in a rabbit skin incision model. Materials and methods: Incisions were performed on the backs of rabbits. The first incision was allowed to undergo normal secondary healing. ABS (1 mL) was applied to the second incision, which was subsequently allowed to undergo secondary healing. The third incision was sutured. ABS (1 mL) was applied to the fourth incision, which was subsequently sutured. During the wound healing period, the histopathologic signs of ulceration, inflammation, the proliferative phase, and the extent of early remodeling were comparatively …
Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk
Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk
Turkish Journal of Medical Sciences
To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. Materials and methods: The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease were noted. Results: The mean age at presentation was 36.23 ± 14.9 years. Males constituted 58.2% of patients. Anatomically, anterior uveitis (42%) was most common, followed by posterior uveitis (24.9%), panuveitis (24.7%), and intermediate uveitis (8.4%). The course of the disease was mostly chronic (65.7%). The …
The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp
The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp
Turkish Journal of Medical Sciences
Letter to the Editor
Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar
Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar
Turkish Journal of Medical Sciences
Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates. The onset is commonly insidious and the poor prognosis is attributed to the long delay in diagnosis. Unfortunately, diagnosis is often delayed until loss of function in the affected tissues has already occurred. The aim of this study was to determine the predictive value of mean platelet volume (MPV) in assessing the risk of intraabdominal hypertension. Materials and methods: Pneumoperitoneum during elective laparoscopic cholecystectomy was used as a model for intraabdominal hypertension. The study included 103 patients who met the …
Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur
Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur
Turkish Journal of Medical Sciences
To determine the overall and comparative incidence of refeeding hypophosphatemia (RH) between enteral and parenteral nutrition in general adult intensive care unit (ICU) patients. Materials and methods: This study was performed as a retrospective analysis. A total of 117 patients who received enteral and parenteral nutrition were included in the study. Demographic characteristics, type of nutrition, daily energy intake, and serum phosphorus levels before and after the initiation of the nutrition were recorded for 7 days. Results: The mean age of the patients was 65.8 ± 16.7 years. RH was found in 61 patients (52.14%). There was no significant difference …
The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren
The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren
Turkish Journal of Medical Sciences
Anesthesiologists have encountered various difficulties in securing the airway. Therefore, we compare the intubation times and hemodynamic changes between the McGrath Series 5 video laryngoscope and the Macintosh laryngoscope. Materials and methods: A total of 80 obstetric patients were divided into 2 groups, orotracheally intubated with either the McGrath video laryngoscope or the Macintosh laryngoscope. The intubation times, Cormack-Lehane grade, percentage of glottic opening, mean arterial blood pressure, and heart rates were compared among the groups. Results: Intubation time in the McGrath video laryngoscope group was significantly longer than in the Macintosh laryngoscope group (P < 0.01). The percentage of glottic opening was found to be higher in the McGrath video laryngoscope group (P = 0.002). Conclusion: The McGrath Series 5 video laryngoscope provides excellent views during orotracheal intubation in obstetric anesthesia with normal airways.
The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek
The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek
Turkish Journal of Medical Sciences
Ventriculoperitoneal shunt infections remain an important problem and result mainly from perioperative colonization of shunt components by skin flora. Antibiotic-impregnated shunts have been designed to prevent such colonization. This study evaluates the incidence of shunt infection after the insertion of antibiotic-impregnated shunts in a population of children with hydrocephalus. Materials and methods: All pediatric patients who had undergone cerebrospinal fluid shunt insertion retrospectively were reviewed over a 6-year period between May 2004 and December 2010. The primary outcome measure was the rate of shunt infections. Patients were followed up with for an average of 26.2 months after shunt surgery, and …
Distribution Of The Hypoglossal Nerve At The Base Of The Tongue And Its Clinical Importance In Radiofrequency Ablation Therapy, Nesri̇n Çandir, Sedat Develi̇, Cenk Kiliç, Bülent Satar, Fati̇h Yazar
Distribution Of The Hypoglossal Nerve At The Base Of The Tongue And Its Clinical Importance In Radiofrequency Ablation Therapy, Nesri̇n Çandir, Sedat Develi̇, Cenk Kiliç, Bülent Satar, Fati̇h Yazar
Turkish Journal of Medical Sciences
To identify the course of the hypoglossal nerve at the base of tongue and to determine a safe area for the placement of radiofrequency ablation therapy (RAT) probes to protect the nerve trunk from any damage. Materials and methods: Anatomical structures located at the base of the tongue were investigated in 10 cadaveric human half-heads. On the base of our landmarks, which are clinically important sign points, measurements were made. Results: The safe area was found to be: in the transverse plane, the 1/2 medial part of the half-tongue between the lateral edge and the foramen caecum of the tongue, …
Comparison Of The Efficacy Of Prednisolone, Montelukast, And Omalizumab In An Experimental Allergic Rhinitis Model, Mete Kaan Bozkurt, Baykal Tülek, Banu Bozkurt, Nalan Akyürek, Mehmet Öz, Aysel Kiyici
Comparison Of The Efficacy Of Prednisolone, Montelukast, And Omalizumab In An Experimental Allergic Rhinitis Model, Mete Kaan Bozkurt, Baykal Tülek, Banu Bozkurt, Nalan Akyürek, Mehmet Öz, Aysel Kiyici
Turkish Journal of Medical Sciences
To compare the efficacy of prednisolone, montelukast, and omalizumab in reducing allergic symptoms and inflammation at tissue level in an experimental allergic rhinitis model. Materials and methods: Forty Sprague Dawley rats were randomized into 5 groups as naive (NS/NC), sensitized/challenged (S/C) by subcutaneous ovalbumin antigen injection, and montelukast-, prednisolone-, and omalizumab-treated groups. A nasal allergen challenge was performed every day from day 20 to day 26. The number of sneezes and nasal/eye rubbing movements, IL-4 and CysLT levels in serum, nasal and bronchoalveolar lavage fluids determined by ELISA, and histopathological findings of nasal mucosa, sinus, and lung tissues were compared. …
Protective Effect Of L-Carnitine In A Rat Model Of Retinopathy Of Prematurity, Sadullah Keleş, İbrahi̇m Caner, Orhan Ateş, Özgür Çakici, Fati̇h Saruhan, Uğur Yilmaz Mumcu, Deni̇z Ünal, Kadi̇r Şerafetti̇n Tekgündüz, Ayhan Taşteki̇n, Ahmet Hacimüftüoğlu, Nesri̇n Gürsan, Hami̇t Hakan Alp
Protective Effect Of L-Carnitine In A Rat Model Of Retinopathy Of Prematurity, Sadullah Keleş, İbrahi̇m Caner, Orhan Ateş, Özgür Çakici, Fati̇h Saruhan, Uğur Yilmaz Mumcu, Deni̇z Ünal, Kadi̇r Şerafetti̇n Tekgündüz, Ayhan Taşteki̇n, Ahmet Hacimüftüoğlu, Nesri̇n Gürsan, Hami̇t Hakan Alp
Turkish Journal of Medical Sciences
To investigate the effects of L-carnitine (LC) on rats with oxygen-induced retinopathy. Materials and methods: The study was conducted on 40 Sprague Dawley rat pups. The rat pups were randomly divided into 4 groups: group 1 (n = 10), the healthy control group with intraperitoneal 0.1 mL/day physiological saline injection; group 2 (n = 10), exposed to hyperoxygen, did not receive LC but received 0.1 mL/day physiological saline intraperitoneally; group 3 (n = 10), exposed to hyperoxygen and received 100 mg/kg/day LC intraperitoneally; group 4 (n = 10), exposed to hyperoxygen and received 200 mg/kg/day LC intraperitoneally. After postnatal day …
The Frequency Of Human Papillomaviruses In Colorectal Cancer Samples In Mashhad, Northeastern Iran, Mojtaba Meshkat, Naser Tayyebi Meibodi, Samaneh Sepahi, Narges Fadaee, Masoumeh Salehpour, Zahra Meshkat
The Frequency Of Human Papillomaviruses In Colorectal Cancer Samples In Mashhad, Northeastern Iran, Mojtaba Meshkat, Naser Tayyebi Meibodi, Samaneh Sepahi, Narges Fadaee, Masoumeh Salehpour, Zahra Meshkat
Turkish Journal of Medical Sciences
Infection with the human papillomaviruses (HPVs) is associated with the development of several cancers, including oral, esophageal, skin, lung, and cervical. However, the association of HPVs and colorectal cancers remains controversial. The aim of this study was to evaluate the association between HPV infection and paraffin-embedded colorectal tissue samples in Mashhad in the northeast of Iran. Materials and methods: Paraffin-embedded tissue specimens from 111 patients with colorectal cancer were subjected to DNA extraction. The quality of extracted DNA was confirmed by amplification of a b-globin fragment using polymerase chain reaction (PCR) and GH20/PCO4 primers. PCR with GP5+/GP6+ primers was then …
Evaluation Of Histopathologic And Histomorphometric Changes Of Testicular Tissue And Gonadotropin Levels Following Consumption Of Methylphenidate In Male Mice, Simin Fazelipour, Zahra Tootian, Zahra Ghahri Saremi, Minoo Shafii, Mohammad Taghi Sheibani, Seyed Babak Kiaei, Mehrnoush Kiumarsi, Fardin Assadi
Evaluation Of Histopathologic And Histomorphometric Changes Of Testicular Tissue And Gonadotropin Levels Following Consumption Of Methylphenidate In Male Mice, Simin Fazelipour, Zahra Tootian, Zahra Ghahri Saremi, Minoo Shafii, Mohammad Taghi Sheibani, Seyed Babak Kiaei, Mehrnoush Kiumarsi, Fardin Assadi
Turkish Journal of Medical Sciences
One of the most common psychiatric disorders in children is attention-deficit/hyperactivity disorder, which is treated extensively by methylphenidate. This study investigates the assessment of the effects of methylphenidate on histopathologic and histomorphometric changes of the testes and serum levels of gonadotropin in mice. Materials and methods: In this study, 36 adult male mice were used. After determining their body weights, the animals were divided randomly into 2 experimental groups and 1 control group. The experimental groups received methylphenidate (2 and 10 mg kg^{-1} day^{-1}) via gavage for a period of 40 days. After evaluation of body weight, general anesthesia was …
The Effect Of Lycopene On The Ototoxicity Induced By Cisplatin, Mehmet Turan Çi̇çek, Mahmut Tayyar Kalci̇oğlu, Tuba Bayindir, Yüksel Toplu, Mustafa Iraz
The Effect Of Lycopene On The Ototoxicity Induced By Cisplatin, Mehmet Turan Çi̇çek, Mahmut Tayyar Kalci̇oğlu, Tuba Bayindir, Yüksel Toplu, Mustafa Iraz
Turkish Journal of Medical Sciences
To determine the efficacy of lycopene, which is considered an antioxidant agent, in decreasing the cochlear damage induced by cisplatin. Materials and methods: A total of 38 rats were randomized into 4 groups: control, cisplatin, cisplatin + lycopene, and lycopene-treated groups. In all groups, the distortion-product otoacoustic emission measurements were performed on days 0, 1, 2, and 5. Results: There were no significant differences between the control and lycopene groups at any frequencies. In the cisplatin group, the statistically significant differences were found in the measurements taken between day 0 and day 5 at all frequencies and between days 1 …
Is There A Genetic Predisposition For Turkish Patients With Sarcoidosis In The 329-Bp Region Containing The Btnl2 Rs2076530 Polymorphism?, Muhsi̇n Özdemi̇r, Faruk Saydam, Emel Kurt, İrfan Deği̇rmenci̇, Tunç Tuncel, Oğuz Çi̇li̇ngi̇r, Hasan Veysi̇ Güneş, Sevi̇lhan Artan
Is There A Genetic Predisposition For Turkish Patients With Sarcoidosis In The 329-Bp Region Containing The Btnl2 Rs2076530 Polymorphism?, Muhsi̇n Özdemi̇r, Faruk Saydam, Emel Kurt, İrfan Deği̇rmenci̇, Tunç Tuncel, Oğuz Çi̇li̇ngi̇r, Hasan Veysi̇ Güneş, Sevi̇lhan Artan
Turkish Journal of Medical Sciences
Sarcoidosis is a complex, multifactorial immune disorder with unknown etiology. A single nucleotide polymorphism ( G->A, rs2076530) in the butyrophilin-like 2 (BTNL2) gene results in a truncating protein formation. It has been previously reported that this variation may be a risk factor for sarcoidosis in certain ethnic groups. This study was conducted to determine whether there is any genetic predisposition for the BTNL2 rs2076530 polymorphism in the 329-bp region in Turkish patients with sarcoidosis. Materials and methods: DNA samples were obtained from volunteers including 53 Turkish patients with sarcoidosis and 52 healthy controls. Analysis of the 329-bp region was …
Clinical And Demographic Findings Of Patients With Rheumatoid Arthritis And Ankylosing Spondylitis Treated In A Tertiary Care Center In Turkey, Özlem Cemeroğlu, Zeynep Sila Yaşar, Mustafa Sağlam, Haşi̇m Çakirbay
Clinical And Demographic Findings Of Patients With Rheumatoid Arthritis And Ankylosing Spondylitis Treated In A Tertiary Care Center In Turkey, Özlem Cemeroğlu, Zeynep Sila Yaşar, Mustafa Sağlam, Haşi̇m Çakirbay
Turkish Journal of Medical Sciences
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are 2 common rheumatic diseases that are frequent causes of disability. In this descriptive study, demographic, clinical, and laboratory findings of patients with RA and AS being followed in a tertiary care center in Turkey were reported. Materials and methods: The patient data of 45 RA and 45 AS cases were collected retrospectively from electronic medical records. Demographic findings, clinical and laboratory assessments of disease activity, drugs used for the treatment, and effect on quality of life of patients with RA and AS were analyzed. Results: In RA patients, 27% had mild, 44% …
Comparison In Clinical Features And Life Impact Between Juvenile-Onset And Adult-Onset Ankylosing Spondylitis, Mingqiang Guan, Jian Wang, Zhigang Zhu, Jun Xiao, Liang Zhao, Zhihan Li, Zhanjun Shi
Comparison In Clinical Features And Life Impact Between Juvenile-Onset And Adult-Onset Ankylosing Spondylitis, Mingqiang Guan, Jian Wang, Zhigang Zhu, Jun Xiao, Liang Zhao, Zhihan Li, Zhanjun Shi
Turkish Journal of Medical Sciences
To compare the differences in clinical characteristics and disease impact on life between patients with juvenile-onset ankylosing spondylitis (JoAS) and patients with adult-onset AS (AoAS). Materials and methods: Demographic and clinical data were collected from 139 AS patients. Disease activity was defined with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Functional status was assessed with the Bath Ankylosing Spondylitis Functional Index (BASFI). Status of quality of life was evaluated with the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire. Results: There were 50 patients with JoAS (36.0%) and 89 with AoAS (64.0%). The JoAS group showed more onset with peripheral …