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Full-Text Articles in Medicine and Health Sciences

Two Gastrointestinal Conditions With Similar Symptoms And Endoscopicappearance: Irritable Bowel Syndrome And Microscopic Colitis, Zahi̇de Şi̇mşek, Nazi̇fe Candan Tunçer, Hakan Alagözlü, Fati̇h Karaahmet, Şahi̇n Çoban, Ayşe Dursun Jan 2015

Two Gastrointestinal Conditions With Similar Symptoms And Endoscopicappearance: Irritable Bowel Syndrome And Microscopic Colitis, Zahi̇de Şi̇mşek, Nazi̇fe Candan Tunçer, Hakan Alagözlü, Fati̇h Karaahmet, Şahi̇n Çoban, Ayşe Dursun

Turkish Journal of Medical Sciences

Background/aim: Irritable bowel syndrome (IBS) is a gastrointestinal condition characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any organic cause. This trial investigated the presence of microscopic colitis (MC) and associated factors related to MC in patients diagnosed with IBS. Materials and methods: The study group (group I) consisted of 91 consecutive patients diagnosed with IBS based on the Rome III Criteria for whom colonoscopic examination was requested. The control group (group II) had 41 patients diagnosed with IBS considered as eligible for colonoscopic investigation due to specific conditions, and for whom …


The Relationship Between Hepatitis Serology Of Ambulance Attendants Andduration Of Education, Ertuğrul Güçlü, Azi̇z Öğütlü, Oğuz Karabay Jan 2015

The Relationship Between Hepatitis Serology Of Ambulance Attendants Andduration Of Education, Ertuğrul Güçlü, Azi̇z Öğütlü, Oğuz Karabay

Turkish Journal of Medical Sciences

Background/aim: Healthcare workers (HCWs) run the risk of hepatitis B virus (HBV) infection. Studies investigating the HBV and hepatitis C virus (HCV) serology of HCWs have been generally conducted in secondary or tertiary hospitals. In this study we aimed to determine the relationships between education level and HBV and HCV serology and HBV vaccination status of ambulance attendants. Materials and methods: The data of this study were obtained by retrospective review of ambulance personnel files in Sakarya Province, Turkey. Results: Out of 314 ambulance attendants, 216 (68.7%; 78 males, 138 females) were enrolled in this study. The mean length of …


Trace Elements Levels In The Serum, Urine, And Semen Of Patients With Infertility, Hasan Sali̇h Sağlam, Hüseyi̇n Altundağ, Yavuz Tarik Ati̇k, Mustafa Şahi̇n Dündar, Öztuğ Adsan Jan 2015

Trace Elements Levels In The Serum, Urine, And Semen Of Patients With Infertility, Hasan Sali̇h Sağlam, Hüseyi̇n Altundağ, Yavuz Tarik Ati̇k, Mustafa Şahi̇n Dündar, Öztuğ Adsan

Turkish Journal of Medical Sciences

Background/aim: Studies suggest that trace elements may have an adverse impact on male reproduction, even at low levels. We tried to investigate the relationships between these metals and semen quality in various body fluids among men with infertility. Materials and methods: A total of 255 samples of blood, semen, and urine were collected from 85 men suffering from infertility. Inductively coupled plasma-optical emission spectrometry was used for the determination of 22 trace elements. We compared the results of the semen parameters with the results of the element determinations. Results: Because of the high proportion of samples with values lower than …


Malondialdehyde And Nitric Oxide Levels And Catalase, Superoxide Dismutase, And Glutathione Peroxidase Levels In Maternal Blood During Different Trimesters Ofpregnancy And In The Cord Blood Of Newborns, Sevda Yüksel, Ayşe Arzu Yi̇ği̇t Jan 2015

Malondialdehyde And Nitric Oxide Levels And Catalase, Superoxide Dismutase, And Glutathione Peroxidase Levels In Maternal Blood During Different Trimesters Ofpregnancy And In The Cord Blood Of Newborns, Sevda Yüksel, Ayşe Arzu Yi̇ği̇t

Turkish Journal of Medical Sciences

Background/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancy with newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes. Materials and methods: Maternal blood samples were collected at 9?13, 22?26, and 36?40 weeks of gestation. Cord blood was collected at the time of delivery. Results: NO levels and GPx activity were higher in the second and third trimesters than in the first trimester. MDA level was lower in the …


Human Papillomavirus: A Potential Risk Factor For Colorectal Carcinoma?, Ufuk Berber, Alpaslan Tanoğlu, Ahmet Zi̇ya Balta Jan 2015

Human Papillomavirus: A Potential Risk Factor For Colorectal Carcinoma?, Ufuk Berber, Alpaslan Tanoğlu, Ahmet Zi̇ya Balta

Turkish Journal of Medical Sciences

No abstract provided.


Pandemic H1n1 Igg Levels In Healthcare Workers, Viroj Wiwanitkit Jan 2015

Pandemic H1n1 Igg Levels In Healthcare Workers, Viroj Wiwanitkit

Turkish Journal of Medical Sciences

No abstract provided.


Caffeic Acid Phenethyl Ester Protects Lung Alveolar Epithelial Cellsfrom Cigarette Smoke-Induced Damage, Firat Bariş Barlas, Suat Erdogan Jan 2015

Caffeic Acid Phenethyl Ester Protects Lung Alveolar Epithelial Cellsfrom Cigarette Smoke-Induced Damage, Firat Bariş Barlas, Suat Erdogan

Turkish Journal of Medical Sciences

Background/aim: To evaluate the influence of caffeic acid phenethyl ester (CAPE) on cigarette smoke (CS)-induced cell damage, oxidative stress, and inflammation in human alveolar epithelial cells. Materials and methods: A549 alveolar epithelial cells were divided into control, CS exposure, CAPE, and CS+CAPE treatment groups. Undiluted CS-exposed medium (100%) and three dilutions (50%, 25%, and 10%) of CS-exposed media were applied to cultured A549 cells, which were analyzed after 3 h of incubation. Viability was measured by MTT assay, the gene expressions were evaluated by real-time PCR, and spectrophotometric techniques were used for biochemical assessments. Results: While CS exposure markedly reduced …


Effect Of Pioglitazone, Quercetin, And Hydroxy Citric Acid On Vascular Endothelial Growth Factor Messenger Rna (Vegf Mrna) Expression In Experimentally Induced Nonalcoholic Steatohepatitis (Nash)*, Surapaneni Krishna Mohan, Vishnu Priya Veeraraghavan, Mallika Jainu Jan 2015

Effect Of Pioglitazone, Quercetin, And Hydroxy Citric Acid On Vascular Endothelial Growth Factor Messenger Rna (Vegf Mrna) Expression In Experimentally Induced Nonalcoholic Steatohepatitis (Nash)*, Surapaneni Krishna Mohan, Vishnu Priya Veeraraghavan, Mallika Jainu

Turkish Journal of Medical Sciences

Background/aim: Vascular endothelial growth factor (VEGF) is associated with various ischemic and inflammatory diseases, and plays an important role in the development of liver fibrosis and hepatocarcinogenesis in nonalcoholic steatohepatitis (NASH). In this study, the comparative effect of pioglitazone, quercetin, and hydroxy citric acid on VEGF mRNA in experimentally induced NASH was investigated. Materials and methods: The experimental protocol consisted of five groups: control, NASH, NASH + pioglitazone, NASH + quercetin, and NASH + hydroxy citric acid. The VEGF mRNA expression was evaluated by reverse transcription polymerase chain reaction (RT-PCR) analysis for all experimental groups, and the levels of VEGF …


Characterization Of Hcv Genotype 4d Infections In Kayseri, Turkey*, Tuba Kayman, Ceylan Polat, Gül Ergör, Yusuf Hakan Abacioğlu Jan 2015

Characterization Of Hcv Genotype 4d Infections In Kayseri, Turkey*, Tuba Kayman, Ceylan Polat, Gül Ergör, Yusuf Hakan Abacioğlu

Turkish Journal of Medical Sciences

Background/aim: The frequency of genotype 4 hepatitis C virus (HCV) infections is significantly higher in Kayseri compared to other provinces in Turkey. We aimed to characterize genotype 4 infections in Kayseri by analyzing the demographic and laboratory data of 218 HCV RNA-positive, treatment-naive patients admitted to the Kayseri Training and Research Hospital in 2010 and 2011. Materials and methods: The distributions of sex, age, and viral loads of these patients with respect to HCV genotypes were analyzed. We also characterized the type 4 sequences at the subtype level. Randomly selected sera from 32 of the 72 genotype 4 patients from …


Clinical Characteristics Of 75 Pandemic H1n1 Influenza Patientsfrom Turkey; Risk Factors For Fatality, Hati̇ce Kiliç, Asi̇ye Kanbay, Ayşegül Karalezli̇, Hati̇ce Canan Hasanoğlu, Can Ateş Jan 2015

Clinical Characteristics Of 75 Pandemic H1n1 Influenza Patientsfrom Turkey; Risk Factors For Fatality, Hati̇ce Kiliç, Asi̇ye Kanbay, Ayşegül Karalezli̇, Hati̇ce Canan Hasanoğlu, Can Ateş

Turkish Journal of Medical Sciences

Background/aim: The 2009 influenza A (H1N1) pandemic caused mild to severe illnesses and led to death in some cases. In this study, we aimed to evaluate the relationship between the serum D-dimer levels, CURB-65 scores, and the severity of pneumonia among patients with H1N1 infections. Materials and methods: Sixty-eight patients who had probable H1N1 infections were evaluated by clinical, radiological, and laboratory methods. The H1N1 strain was specified by reverse transcription-polymerase chain reaction. Of 55 patients diagnosed with pneumonia, 18 exhibited H1N1 positivity and 37 patients did not. Results: CURB-65 scores of pneumonia patients with H1N1 (group 1) were higher …


Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t Jan 2015

Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t

Turkish Journal of Medical Sciences

Background/aim: Mycological media that promote spore production are essential for the diagnosis of dermatophytosis. However, these culture media frequently become contaminated by multiple fungal or bacterial species during culture. The aim of this study was to compare the contamination rates of 6 culture media used for the isolation and identification of dermatophytes, including Borelli's lactritmel agar (BLA), brain-heart infusion agar (BHIA), Lowenstein-Jensen agar (LJA), malt extract agar (MEA), potato dextrose agar (PDA), and Sabouraud glucose agar (SGA). Materials and methods: Agar plates were inoculated with 43 well-characterized dermatophyte strains, belonging to the genera Arthroderma, Epidermophyton, Microsporum, or Trichophyton. The agar …


Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk Jan 2015

Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk

Turkish Journal of Medical Sciences

Background/aim: To determine the role of matrix metalloproteinases (MMPs) and their relationship with the clinical course of community-acquired pneumonia (CAP). Materials and methods: Sixty-two consecutively hospitalized patients with CAP were enrolled and their pneumonia severity index (PSI), time to clinical stability (TCS), treatment response, and complications were recorded. The pre- and posttreatment serum concentrations of MMPs and their inhibitors were analyzed by ELISA. The activities of MMPs were evaluated by gelatin zymography. Results: MMP-2 and -9 serum levels and their activities were higher in CAP patients than controls (P < 0.001 and P < 0.001, respectively). Low-risk patients had lower levels of MMP-2 and TIMP-1 than high-risk patients (P = 0.044, P = 0.001, respectively). Pretreatment serum TIMP-1 level was higher in patients with TCS of >3 days (P = 0.004) and was correlated with oxygenation and …


Correlation Between Serum Levels Of Vitamin B12 And Anti-Helicobacter Pyloriiga Antibodies In Vitamin B12 Deficient Palestinian Patients, Rasmi Abu Hilu, Osama Dudeen, Sameer Abdullatif Barghouthi Jan 2015

Correlation Between Serum Levels Of Vitamin B12 And Anti-Helicobacter Pyloriiga Antibodies In Vitamin B12 Deficient Palestinian Patients, Rasmi Abu Hilu, Osama Dudeen, Sameer Abdullatif Barghouthi

Turkish Journal of Medical Sciences

Background/aim: H. pylori infection and vitamin B12 (vB12) deficiency have high prevalence rates among Palestinians. It was observed that most people who suffered from vB12 deficiency were positive for H. pylori. Materials and methods: The correlation between H. pylori infection and vB12 deficiency was investigated in a representative segment of the Palestinian population. ELISA was used to determine levels of vitamin B12 (vB12) and anti-H. pylori IgA in sera from 238 participants from Al-Khalil district (Hebron), Palestine. Results: There was a strong negative Pearson's correlation coefficient (r = -0.45; P = 0.00001) between levels of anti-H. pylori IgA and vB12 …


Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji Jan 2015

Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji

Turkish Journal of Medical Sciences

Background/aim: Sp1 polymorphism of type I collagen genes is accompanied with bone c??ollagen disorders and severe clinical phenotypes such as osteogenesis imperfecta. The aim of this study was to study the association between COLIA1 Sp1 polymorphism and bone density rate. Materials and methods: In this descriptive, analytical study conducted in 2013 in southwestern Iran, 200 blood samples, per the Cochran sample size formula, were taken from women aged 45 and older. DNA was extracted from the samples using the phenol-chloroform method and the genomic fragments in question were proliferated using the polymerase chain reaction (PCR) method. Results: The genotype distribution …


The Hematologic Manifestations Of Pediatric Celiac Disease At The Time Ofdiagnosis And Efficiency Of Gluten-Free Diet, Ferat Çatal, Erdem Topal, Hali̇me Ermi̇şteki̇n, Nurdan Yildirim Acar, Muhammed Selçuk Si̇nanoğlu, Hamza Karabi̇ber, Mukadder Ayşe Seli̇moğlu Jan 2015

The Hematologic Manifestations Of Pediatric Celiac Disease At The Time Ofdiagnosis And Efficiency Of Gluten-Free Diet, Ferat Çatal, Erdem Topal, Hali̇me Ermi̇şteki̇n, Nurdan Yildirim Acar, Muhammed Selçuk Si̇nanoğlu, Hamza Karabi̇ber, Mukadder Ayşe Seli̇moğlu

Turkish Journal of Medical Sciences

Background/aim: To determine the hematologic manifestations at the time of diagnosis of celiac disease in children and the effects of a gluten-free diet on hematologic signs upon follow-up. Materials and methods: The records of patients with celiac disease who received a follow up examination at the Pediatric Gastroenterology Clinic between June 2006 and June 2013 were retrospectively examined. Results: Ninety-one patients were included in the study. The mean age at diagnosis was 8.1 ± 4.21 years and 59 patients (64.8%) were female. Thirty-two patients (35.2%) had hematologic signs at the time of diagnosis. Anemia (24.2%) was the most common hematologic …


Efficacy Of Diffusion-Weighted Magnetic Resonance Imaging In The Evaluation Of Extrahepatic Cholestasis-Related Hepatic Fibrosis, Süleyman Ayvaz, Sedat Alpaslan Tuncel, Güray Can, Beki̇r Çağli, Turan Karaca, Seli̇m Demi̇rtaş, Muhammed Elmaoğlu, Mehmet Ercüment Ünlü, Mehmet Pul Jan 2015

Efficacy Of Diffusion-Weighted Magnetic Resonance Imaging In The Evaluation Of Extrahepatic Cholestasis-Related Hepatic Fibrosis, Süleyman Ayvaz, Sedat Alpaslan Tuncel, Güray Can, Beki̇r Çağli, Turan Karaca, Seli̇m Demi̇rtaş, Muhammed Elmaoğlu, Mehmet Ercüment Ünlü, Mehmet Pul

Turkish Journal of Medical Sciences

Background/aim: To investigate the efficacy of diffusion-weighted magnetic resonance imaging (DWI) in the diagnosis and staging of fibrosis induced by experimental bile duct ligation (BDL). Materials and methods: Twenty-four rats were divided randomly into four groups: control, BDL - 3 days, BDL - 2 weeks, and BDL - 4 weeks. DWI was performed with b-values of 100 and 500 on the rats from control group at day zero, on the rats from the BDL - 3 days group at the end of day 3, on the rats from the BDL - 2 weeks group at the end of day 14, …


Efficacy Of Wound Infiltration With Lornoxicam For Postoperative Analgesiafollowing Thyroidectomy: A Prospective, Randomized, Double-Blind Study, Zafer Kilbaş, Mustafa Öner Menteş, Ali̇ Harlak, Taner Yi̇ği̇t, Sali̇h Müjdat Balkan, Ahmet Coşar, Erkan Öztürk, Orhan Kozak, Cemi̇l Turgut Tufan Jan 2015

Efficacy Of Wound Infiltration With Lornoxicam For Postoperative Analgesiafollowing Thyroidectomy: A Prospective, Randomized, Double-Blind Study, Zafer Kilbaş, Mustafa Öner Menteş, Ali̇ Harlak, Taner Yi̇ği̇t, Sali̇h Müjdat Balkan, Ahmet Coşar, Erkan Öztürk, Orhan Kozak, Cemi̇l Turgut Tufan

Turkish Journal of Medical Sciences

Background/aim: Postoperative pain control constitutes a major problem and studies have focused on reducing opioid requirements using regional techniques. We aimed to investigate the efficacy of wound infiltration with lornoxicam on postoperative pain control following thyroidectomy. Materials and methods: In this prospective, randomized-controlled study, 80 patients scheduled for thyroidectomy were randomly assigned to 2 groups. After the thyroidectomy was performed, patients in group I underwent wound infiltration with 4 mg of lornoxicam and patients in group II received the same amount of saline. Rescue analgesia was provided with additional doses of lornoxicam delivered by an on-demand patient-controlled analgesia device. Total …


Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan Jan 2015

Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan

Turkish Journal of Medical Sciences

Background/aim: To examine the relationship between sociodemographic and pregnancy features and fetal health locus of control (FHLC) in a sample of pregnant Turkish women. Materials and methods: The study was conducted with 256 pregnant women. Data were collected by demographic questionnaire and the FHLC Scale consisting of 3 components: 1) Internality Scale (FHLC-I), 2) Powerful Others Scale (FHLC-P), and 3) Chances Scale (FHLC-C). Results: The age of marriage was found to have a positive relation with FHLC-I (r = 0.141) and a negative relation with FHLC-C (r = -0.145) (P < 0.05). The age of first pregnancy was found to have a positive relation with FHLC-I (r = 0.127). Those who have a low educational level (r = -0.258) and income (r = -0.149), who are unemployed (r = -2.839), whose number of pregnancies is high (r = 0.152), who get pregnant unplanned (r = 3.839), and who come to their first prenatal examination late (r = -0.142) have a significantly high score of FHLC-C (P


Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren Jan 2015

Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren

Turkish Journal of Medical Sciences

Background/aim: To evaluate patients hospitalized in our clinic in the last 5 years with the diagnosis of intrahepatic cholestasis of pregnancy (ICP). Materials and methods: One hundred and fifty patients hospitalized with a diagnosis of ICP between January 2008 and May 2013 were evaluated retrospectively and age, week at diagnosis, gestational age at delivery, period between diagnosis and delivery, fetal weight, transaminases, and coagulation parameters were recorded. Patients were divided into groups according to their diagnosis weeks and gravida. Accordingly, patients diagnosed before 32 weeks formed group A (n = 49) and those after 32 weeks formed group B (n …


Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren Jan 2015

Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren

Turkish Journal of Medical Sciences

No abstract provided.


Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n Jan 2015

Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n

Turkish Journal of Medical Sciences

No abstract provided.


The Evaluation Of Transient Hypothyroidism In Patients Diagnosedwith Congenital Hypothyroidism, Havva Nur Peltek Kendi̇rci̇, Zehra Aycan, Eli̇f Sağsak, Meli̇kşah Keski̇n, Semra Çeti̇nkaya Jan 2015

The Evaluation Of Transient Hypothyroidism In Patients Diagnosedwith Congenital Hypothyroidism, Havva Nur Peltek Kendi̇rci̇, Zehra Aycan, Eli̇f Sağsak, Meli̇kşah Keski̇n, Semra Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: Congenital hypothyroidism (CH) is divided into two groups as 'permanent' and 'transient'. We aimed to determine the rate of transient and permanent congenital hypothyroidism of the newborns referred to our clinic. Materials and methods: Of the newborns who were referred to our clinic from the neonatal screening program, those who were diagnosed with CH and started treatment were included in the study. The treatments of the patients whose required daily treatment dose was reduced to under 1 µg/kg were terminated and those who were followed monthly and whose fT4 and thyroid-stimulating hormone (TSH) levels were normal at least 3 …


Bilateral Sympathicotomy For Hyperhidrosis Without Using Single-Lung Ventilation, Tevfi̇k Kaplan, Peri̇han Ekmekçi̇, Bülent Koçer, Serdar Han Jan 2015

Bilateral Sympathicotomy For Hyperhidrosis Without Using Single-Lung Ventilation, Tevfi̇k Kaplan, Peri̇han Ekmekçi̇, Bülent Koçer, Serdar Han

Turkish Journal of Medical Sciences

Background/aim: The goal of this retrospective study was to evaluate the outcomes and complications of bilateral videothoracoscopic sympathicotomy without using single-lung ventilation in the treatment of primary hyperhidrosis and facial blushing. Materials and methods: We retrospectively reviewed 154 consecutive patients (70 females and 84 males) who underwent bilateral sympathicotomy for palmar, axillary, and facial/scalp hyperhidrosis or facial blushing from February 2005 to June 2013. The patients were intubated with single-lumen endotracheal tube, and then sympathicotomies were performed via videothoracoscopy during controlled apnea periods. Results: Sympathicotomies were performed at costal levels 2, 3, and 4. No perioperative mortality or conversion to …


Self-Perception Of Quality Of Life In Patients Treated With Antipsychotics, Lorena Dima, Daniel Vasile, Liliana Rogozae, Muhammad Zia-Ul-Haq, Shazia Anwer Bukhari, Marius Moga Jan 2015

Self-Perception Of Quality Of Life In Patients Treated With Antipsychotics, Lorena Dima, Daniel Vasile, Liliana Rogozae, Muhammad Zia-Ul-Haq, Shazia Anwer Bukhari, Marius Moga

Turkish Journal of Medical Sciences

Background/aim: Despite extensive research, normal functionality remains problematic in patients with schizophrenia. Issues such as quality of life, subjective well-being, or psychosocial performance are currently objectives of interest. There are limited data collected prospectively on patients' perception of quality of life as compared between treatment groups, especially in developing countries. The aim of the present study was to analyze the evolution of patients' reported quality of life in patients with schizophrenia or related disorders treated with antipsychotics, in naturalistic settings. Materials and methods: The study was designed as a 12-month prospective observational study of 131 subjects with schizophrenia or related …


Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar Jan 2015

Multidrug Resistance And Integron Carriage In Clinical Isolates Ofpseudomonas Aeruginosa In Tehran, Iran, Somayeh Moazami Goudarzi, Fereshteh Eftekhar

Turkish Journal of Medical Sciences

Background/aim: Pseudomonas aeruginosa is the cause of 10% of hospital-acquired infections. The organisms are often multidrug-resistant, mediated mostly by antibiotic-resistant integrons. The aim of this research was to study integron carriage and its association with multidrug resistance in burn and nonburn clinical isolates of P. aeruginosa. Materials and methods: A total of 112 P. aeruginosa clinical isolates were collected from the Motahari and Shohadaye Tajrish hospitals in Tehran between July and December 2011. Antibiotic susceptibility to 13 antibiotics was determined by disk diffusion. Detection of integron classes 1 and 2 and amplifications of internal variable regions (IVRs) of class 1 …


The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç Jan 2015

The Effects Of Aspirin, Flurbiprofen, And No-Donating Acetylsalicylic Acid(Ncx 4016) On Mice Models Of Endotoxic And Septic Shock, Nadi̇r Ulu, Alper Bektaş İski̇t, Cenk Sökmensüer, Mustafa Oğuz Güç

Turkish Journal of Medical Sciences

Background/aim: Nitric oxide-donating nonsteroidal antiinflammatory drugs (NO-NSAIDs) are a promising new class of antiinflammatory agents, which are obtained by adding NO-donating moieties to the existing conventional NSAID molecules. The aim of this study was to investigate the effects of aspirin, flurbiprofen, and NO-donating acetylsalicylic acid (NCX 4016) on cecal ligation and puncture (CLP) and endotoxin-induced septic shock (LPS) models in mice. Materials and methods: Overall survival and spleen and liver weights were monitored in LPS and CLP models. Histopathological examinations of liver and spleen were performed at the end of the experimental protocols. Results: NCX 4016 was able to reverse …


Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy Jan 2015

Epidemiology, Causative Agents, And Risk Factors Affecting Humanotomycosis Infections, Metwally Abdelazeem, Ahmed Gamea, Hanan Mubarak, Nessma Elzawawy

Turkish Journal of Medical Sciences

Background/aim: Otomycosis, or fungal otitis externa, has typically been described as fungal infection of the external auditory canal, with infrequent complications involving the middle ear. This study assessed a mycological analysis of fungal debris from external auditory canals of patients at Tanta University Hospital, Gharbia Governorate, Egypt. Materials and methods: The samples were collected over a year from the 110 patients that were clinically diagnosed to have otomycosis. The samples were then inoculated and culture plates were examined for the presence of fungal growth. Results: The results showed that Aspergillus niger was the most common fungus causing otomycosis. It was …


The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu Jan 2015

The Risk Of Tumor Cell Dissemination In Mediastinoscopy: A Cytological Study, Yasemi̇n Bi̇lgi̇n Büyükkarabacak, Ayşen Taslak Şengül, Bi̇lge Can Meydan, Burçi̇n Çeli̇k, Mehmet Gökhan Pi̇rzi̇renli̇, Selçuk Gürz, Zeynep Peli̇n Sürücü, Ahmet Başoğlu

Turkish Journal of Medical Sciences

Background/aim: Mediastinoscopy is an invasive procedure that is used in the diagnosis of mediastinal diseases and in staging lung cancer. Tumor cell seeding during mediastinoscopy along the mediastinum and the incision line is a very rare complication. This study aimed to test the safety of mediastinoscopy in terms of tumor seeding by cytological evaluation of mediastinal lavage samples taken before and after biopsy. Materials and methods: The patients who underwent mediastinoscopy in our hospital between 2011 and 2014 were studied prospectively. Seventy-three patients with a diagnosis of lung or mediastinal malignancy were included in the study. All patients underwent classical …


Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu Jan 2015

Does Atraucan Cause More Postdural Puncture Backache?, Ruslan Abdullayev, Ömer Burak Küçükebe, Bülent Çeli̇k, Ni̇hal Ki̇rman, Hami̇t Si̇nan Hati̇poğlu, Fi̇li̇z Akaltun Hati̇poğlu

Turkish Journal of Medical Sciences

Background/aim: Postdural puncture backache (PDPB) is the most frequent complaint after spinal anesthesia. In the literature its importance is generally overshadowed by postdural puncture headache. We studied two different kinds of spinal anesthesia needles to compare their technical handling capacities and incidences of PDPB. Materials and methods: Data of 256 pregnant female patients undergoing cesarean delivery under spinal anesthesia were collected for the study. Patients were divided into two groups as Group A (n = 109) and Group Q (n = 147) according to the spinal needle used for spinal anesthesia (i.e. 26-gauge atraumatic and 26-gauge Quincke needles, respectively). Backache …


Acute Tuberculosis In The Intensive Care Unit, Kazim Rollas, Ati̇la Kara, Nazmi̇ye Ebru Ortaç Ersoy, Kezban Özmen Süner, Mehmet Nezi̇r Güllü, Serpi̇l Öcal, Arzu Topeli̇ Jan 2015

Acute Tuberculosis In The Intensive Care Unit, Kazim Rollas, Ati̇la Kara, Nazmi̇ye Ebru Ortaç Ersoy, Kezban Özmen Süner, Mehmet Nezi̇r Güllü, Serpi̇l Öcal, Arzu Topeli̇

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine mortality rates and to evaluate clinical features of patients with active tuberculosis (TB) requiring intensive care unit (ICU) admission. Materials and methods: The medical records of active TB patients requiring ICU admission were retrospectively reviewed over a 5-year period. Results: Sixteen patients with active TB admitted to the ICU were included in the study. Seven (43.8%) patients died in the ICU. The cause of mortality was septic shock in 5 patients and respiratory failure in 2 patients. The Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure …