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Articles 2191 - 2220 of 4871
Full-Text Articles in Medicine and Health Sciences
A Study On The Validity And Reliability Of The Amblyopia Andstrabismus Questionnaire (A&Sq) In Turkish, Hali̇se Çoşkun, Sevi̇nç Taştan, Emi̇ne İyi̇gün, Fati̇h Mehmet Mutlu, Osman Meli̇h Ceylan, Hali̇l İbrahi̇m Altinsoy
A Study On The Validity And Reliability Of The Amblyopia Andstrabismus Questionnaire (A&Sq) In Turkish, Hali̇se Çoşkun, Sevi̇nç Taştan, Emi̇ne İyi̇gün, Fati̇h Mehmet Mutlu, Osman Meli̇h Ceylan, Hali̇l İbrahi̇m Altinsoy
Turkish Journal of Medical Sciences
Background/aim: This study aims to evaluate the reliability and validity of the Amblyopia and Strabismus Questionnaire (A&SQ) that is translated into Turkish. Materials and methods: This is a methodological study. A total of 149 patients took part in the survey research between December 2012 and June 2014 in an university hospital, and 37 were retested. Cronbach's alpha coefficient was used for the questionnaire's reliability analysis. Results: Cronbach's alpha coefficients for the subscales of fear of losing the better eye, distance estimation, visual disorientation, double vision, and social contact and appearance were found to be 0.80, 0.88, 0.95, 0.80, and 0.81, …
Allergic And Autoimmune Disorders In Families With Selective Iga Deficiency, Mustafa Erkoçoğlu, Ayşe Meti̇n, Ayşenur Kaya, Celal Özcan, Ayşegül Akan, Ersoy Ci̇velek, Murat Çapanoğlu, Tayfur Gi̇ni̇ş, Can Naci̇ Kocabaş
Allergic And Autoimmune Disorders In Families With Selective Iga Deficiency, Mustafa Erkoçoğlu, Ayşe Meti̇n, Ayşenur Kaya, Celal Özcan, Ayşegül Akan, Ersoy Ci̇velek, Murat Çapanoğlu, Tayfur Gi̇ni̇ş, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Background/aim: IgA deficiency is the most common human primary immunodeficiency. The prevalence of allergic disorders and autoimmunity is thought to be increased in selective IgA deficiency (sIgAD). However, it is currently unclear if these disorders coincide within these families. We aimed to evaluate the frequency of allergic and autoimmune disorders in children with sIgAD and their firstdegree relatives (FDRs). Materials and methods: The study included 81 children diagnosed with sIgAD and 274 of their FDRs. The presence of allergic and autoimmune disorders was evaluated and serum antithyroglobulin and antithyroid peroxidase levels were measured in both patients and their first-degree relatives. …
Association Of The Cetp Gene Taqib And D442g Polymorphisms With Essentialhypertension In The Chinese Mongolian Population, Shudong Niu, Xiaoming Tao, Jingping Li, Yongyue Liu, Jian Wang, Mingyu Cong, Keyong Zhang, Wenyu Zhou, Changchun Qiu
Association Of The Cetp Gene Taqib And D442g Polymorphisms With Essentialhypertension In The Chinese Mongolian Population, Shudong Niu, Xiaoming Tao, Jingping Li, Yongyue Liu, Jian Wang, Mingyu Cong, Keyong Zhang, Wenyu Zhou, Changchun Qiu
Turkish Journal of Medical Sciences
Background/aim: This study aimed to explore the associations of the cholesteryl ester transfer protein (CETP) gene TaqIB and D442G polymorphisms with essential hypertension (EH). Materials and methods: In this case-control study, 883 hypertensive patients and 1044 normal controls were randomly selected from the Mongolian population of China. Polymerase chain reaction (PCR) and direct sequencing of PCR products were used to identify the genotypes. Haplotype analysis was performed by estimating the haplotype frequencies using the online SHEsis package. Results: The distribution frequency of the B2-G haplotype was significantly lower in the EH group than in the control group (0.7% vs. 1.9%, …
Wheezing, Asthma, And Atopy In Premature Infants At 2 Years Of Age, Sevi̇m Ünal, Ayşenur Kaya, Leyla Bi̇lgi̇n, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Wheezing, Asthma, And Atopy In Premature Infants At 2 Years Of Age, Sevi̇m Ünal, Ayşenur Kaya, Leyla Bi̇lgi̇n, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Background/aim: We aimed to evaluate wheezing, bronchial asthma (BA), and atopy in premature infants at 2 years of age via a crosssectional study. Materials and methods: Premature infants at <37 weeks of gestational age (GA) were assessed for atopy by skin-prick test and serum immunoglobulin E level at 2 years of age. The family's and infant's histories of allergy, BA, atopy, and wheezing were obtained by questionnaire and from hospital records. Results: There were 98 infants, with mean birth weight (BW) 1517.4 ± 486.5 g and GA 30.8 ± 2.9 weeks. The frequencies of wheezing, asthma, and bronchopulmonary dysplasia (BPD) were 32.7%, 16.3%, and 14.3%, respectively. Skin-prick tests were positive for 11 subjects, with allergy to cereals for 7 infants, egg for 3, and peanut for 1. Wheezing was related to GA, BW, respiratory distress syndrome, mechanical ventilation, sepsis, asphyxia, smoking, antenatal steroid, BA, palivizumab prophylaxis, number of people in the household, and duration of hospitalization (P < 0.05). Wheezing was negatively correlated to GA. Family history of BA, smoking, and number of people in the household were linked to BA (P < 0.05). Conclusion: Wheezing was related to degree of premature birth, but BA was linked to BA in the family and smoking. Increased gestation should improve the infant's respiratory health up to 2 years of age.
Prediction Of Atopy Via Total Immunoglobulin E Levels Andskin Prick Tests In Patients With Psoriasis, Emi̇ne Sümeyye Ünal, Ülker Gül, Adi̇le Berna Dursun, Ferda Öner Erkekol
Prediction Of Atopy Via Total Immunoglobulin E Levels Andskin Prick Tests In Patients With Psoriasis, Emi̇ne Sümeyye Ünal, Ülker Gül, Adi̇le Berna Dursun, Ferda Öner Erkekol
Turkish Journal of Medical Sciences
Background/aim: Although the etiopathogeneses of psoriasis and atopy appear to be different, psoriasis has been found to be associated with atopy and atopic dermatitis. In this study, we aimed to determine the role of atopy by examining the medical history and clinical and laboratory findings of patients with psoriasis. Materials and methods: Patients with psoriasis, asthma patients, and healthy volunteers were included in the study. Serum total immunoglobulin E (IgE) levels were obtained, and prick tests were administered to all groups. Results: Psoriatic patients demonstrated percentages of atopy history (21.3%) that were higher than those of the healthy subjects (15.7%). …
Central Line-Associated Blood Stream Infections: Characteristics And Risk Factors Formortality Over A 5.5-Year Period, Aynur Ati̇lla, Zahi̇de Doğanay, Hale Kefeli̇ Çeli̇k, Mehmet Derya Demi̇rağ, Süleyman Sirri Kiliç
Central Line-Associated Blood Stream Infections: Characteristics And Risk Factors Formortality Over A 5.5-Year Period, Aynur Ati̇lla, Zahi̇de Doğanay, Hale Kefeli̇ Çeli̇k, Mehmet Derya Demi̇rağ, Süleyman Sirri Kiliç
Turkish Journal of Medical Sciences
Background/aim: Central line-associated bloodstream infections (CLABSIs) are associated with substantial morbidity and mortality and the infection rates vary in a wide range (high: 62.5%; low: 20%) in developing countries. We aimed to investigate the characteristics and the risk factors for mortality in patients with CLABSIs in intensive care units (ICUs) and provide the relevant data. Materials and methods: The electronic medical records database and file records obtained through active surveillance by an infection control committee of a hospital were screened to identify patients with CLABSIs hospitalized from January 2008 through July 2013. Results: A total of 166 CLABSI episodes in …
The Efficacy Of Microphototherapy With A Medlight Cupcubegrimed Device In Psoriatic Patients With Localized Lesions, Nesli̇han Yildirim, Gül Erki̇n
The Efficacy Of Microphototherapy With A Medlight Cupcubegrimed Device In Psoriatic Patients With Localized Lesions, Nesli̇han Yildirim, Gül Erki̇n
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is a chronic skin disease. To reduce side effects associated with current treatment modalities, new treatment methods are required. Some clinicians have begun to use microphototherapy to treat psoriatic patients with a limited number of lesions (lesions affecting <10% of the body surface area). Materials and methods: Microphototherapy is indicated in patients whose lesions persist despite systemic and topical treatment or when such treatment is contraindicated. Our study aimed to evaluate the efficacy of microphototherapy in psoriasis patients with localized lesions. Patients in this unblinded and prospective study were treated three times a week for 50 sessions using a MedLight CupCUBE Grimed microphototherapy device that emits an ultraviolet B (UVB) spectrum. Results: Forty-five lesions in 23 psoriatic patients were treated. Treatment outcome was evaluated based on the Psoriasis Severity Index (PSI). PSI scores decreased significantly during the treatment. Conclusion: The MedLight CupCUBE Grimed microphototherapy device was effective for the treatment of psoriasis patients with localized lesions. The device can administer UVB radiation to involved regions while protecting uninvolved regions and minimizing radiation dose. However, having to be administered by experienced technicians and the long time required for each treatment session are disadvantages of the technique.
Effects Of Ankaferd Bloodstopper On Dermal Healing In Diabetic Rats, Sertaç Aktop, Burcu Çevreli̇, Deni̇z Genç, Emel Serdaroğlu Kaşikçi, Ni̇l Çomunoğlu Üstündağ, Noushi̇n Zi̇bandeh, Eli̇f Merve Özcan, Gökhan Göçmen, Mehmet Kami̇l Göker, İsmai̇l Tayfun Uzbay, Tunç Akkoç
Effects Of Ankaferd Bloodstopper On Dermal Healing In Diabetic Rats, Sertaç Aktop, Burcu Çevreli̇, Deni̇z Genç, Emel Serdaroğlu Kaşikçi, Ni̇l Çomunoğlu Üstündağ, Noushi̇n Zi̇bandeh, Eli̇f Merve Özcan, Gökhan Göçmen, Mehmet Kami̇l Göker, İsmai̇l Tayfun Uzbay, Tunç Akkoç
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus inhibits wound-induced angiogenesis, impairs the wound healing process, and leads to the development of chronic wounds. Ankaferd BloodStopper (ABS) is a new and promising local haemostatic agent. Although the mechanism of ABS-mediated haemostasis is well established, little is known about the associated histological and biochemical tissue reactions. The aim of this study was to evaluate the effects of this new-generation local haemostatic agent on short-term soft-tissue healing in streptozotocin (STZ)-treated rats. Materials and methods: The 24 Wistar albino rats used in this study were divided into STZ-treated (STZ, n = 12) and nontreated groups (control, n = …
Modifications Of Mice Gut Microflora Following Oral Consumption Oflactobacillus Acidophilus And Bifidobacterium Bifidum Probiotics, Hossein Khavari-Daneshvar, Maryam Mosavi, Hamid Khodayari, Ebrahim Rahimi, Peyman Ranji, Amir Hossein Mohseni, Reyhaneh Mahmudian, Farzad Shidfar, Shahram Agah, Ali Mohammad Alizadeh
Modifications Of Mice Gut Microflora Following Oral Consumption Oflactobacillus Acidophilus And Bifidobacterium Bifidum Probiotics, Hossein Khavari-Daneshvar, Maryam Mosavi, Hamid Khodayari, Ebrahim Rahimi, Peyman Ranji, Amir Hossein Mohseni, Reyhaneh Mahmudian, Farzad Shidfar, Shahram Agah, Ali Mohammad Alizadeh
Turkish Journal of Medical Sciences
Background/aim: Thirty male BALB/c mice were equally divided into three groups: control, L. acidophilus, and B. bifidum for the assessment of the probiotics' stability in the gut microflora. Materials and methods: First, the gut microflora of the mice was checked every 3 days (days 3, 6, 9, and 12) without probiotic consumption, and then the mice were daily given orally 1.5 g of probiotics in 30 cc of drinking water. The consumption of probiotics was then stopped for recovery and then the consumption continued for 5 months. Results: On day 9 after the consumption of the probiotics, L. acidophilus and …
Efficient Production Of Nanobodies Against Urease Activity Ofhelicobacter Pylori In Pichia Pastoris, Shahrbanoo Pourasadi, Seyed Latif Mousavi Gargari, Masoumeh Rajabibazl, Shahram Nazarian
Efficient Production Of Nanobodies Against Urease Activity Ofhelicobacter Pylori In Pichia Pastoris, Shahrbanoo Pourasadi, Seyed Latif Mousavi Gargari, Masoumeh Rajabibazl, Shahram Nazarian
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori is a major health problem. One of the therapeutic approaches is administration of antibody against H. pylori. The methylotrophic Pichia pastoris is a suitable host for expression of recombinant antibody fragments. The aims of this study were the expression and the evaluation of camelid nanobody in the yeast Pichia pastoris. Materials and methods: The camelid-derived heavy-chain antibody (nanobody) against the UreC subunit of urease from H. pylori was subcloned in the pPink-HC shuttle vector and transferred into Escherichia coli TOP10. After digestion and purification, the shuttle vector was transformed in the PichiaPink expression system. The expression was …
Evaluation Of Cytotoxic, Membrane, And Dna Damaging Effects Of Thymus Revolutuscélak Essential Oil On Different Cancer Cells, Aysun Özkan, Ayşe Erdoğan
Evaluation Of Cytotoxic, Membrane, And Dna Damaging Effects Of Thymus Revolutuscélak Essential Oil On Different Cancer Cells, Aysun Özkan, Ayşe Erdoğan
Turkish Journal of Medical Sciences
Background/aim: In this study, we evaluated Thymus revolutus Célak essential oil and its two main constituents, γ-terpinene and p-cymene, as potential oxidative agents against lung cancer and epidermoid carcinoma cells. Materials and methods: Cell viability assessment was made by CellTiter-Blue® cell viability and 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay after treatment with 5?600 ?g/mL concentrations of essential oil, γ-terpinene, and p-cymene. Malondialdehyde and 8-hydroxy-2'-deoxyguanosine levels in parental H1299, epirubicin-resistant (drug-resistant) H1299, A549, and A431 cells were also assayed after essential oil, γ-terpinene, and p-cymene had been administered for 24 h. Glutathione S-transferase (GST), glutathione peroxidase (GPx), glutathione reductase (GRx), and glucose …
Psychosocial Functioning In Pediatric Patients With Pectus Excavatum And Pectus Carinatum, Ali̇ye Tuğba Bahadir, Pinar Kuru, Ayli̇n Çakiroğlu, Ceyda Afacan, Mustafa Yüksel
Psychosocial Functioning In Pediatric Patients With Pectus Excavatum And Pectus Carinatum, Ali̇ye Tuğba Bahadir, Pinar Kuru, Ayli̇n Çakiroğlu, Ceyda Afacan, Mustafa Yüksel
Turkish Journal of Medical Sciences
Background/aim: Pectus excavatum and pectus carinatum are the most commonly seen anterior chest wall deformities. Recent studies reveal that minimal invasive repair of pectus deformities improves the quality of life. Our aim is to assess the psychosocial functioning and sociodemographic characteristics of pediatric patients with pectus deformities and evaluate the differences between patients operated on with minimal invasive repair techniques and nonoperated patients. Materials and methods: Thirty-two patients with pectus deformities who were operated on 6 months or more before and 31 nonoperated patients participated in the study. The Children's Depression Inventory, Piers-Harris Children's Self-Concept Scale, Capa Social Phobia Scale …
Antioxidants Status In Type 2 Diabetic Patients In Morocco, Rachid Eljaoudi, Naoual Elomri, Meryem Laamarti, Yahia Cherrah, Taoufik Amezyane, Driss Ghafir, Azeddine Ibrahimi
Antioxidants Status In Type 2 Diabetic Patients In Morocco, Rachid Eljaoudi, Naoual Elomri, Meryem Laamarti, Yahia Cherrah, Taoufik Amezyane, Driss Ghafir, Azeddine Ibrahimi
Turkish Journal of Medical Sciences
Background/aim: Type 2 diabetes is a heterogeneous and multifactorial metabolic disorder with some relationship to oxidative stress (OS). Since no studies were conducted in the Moroccan population, this clinical investigation aimed at evaluating the antioxidants status in Moroccan patients with type 2 diabetes. Materials and methods: Blood samples of 60 type 2 diabetic patients and 40 healthy controls subjects were analyzed for determination of glycemia, hemoglobin, CRP, glycated hemoglobin, lipid parameters, malondialdehyde (MDA), vitamins E and C, copper (Cu), zinc (Zn), and selenium (Se). Results: CRP and triglycerides were higher in the diabetic group while high-density lipoprotein levels were significantly …
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
Turkish Journal of Medical Sciences
Background/aim: Clinicians associate the changes in cervical lordosis with neck pain, but there is no clear consensus on this. We aimed to investigate the relationships of cervical angles, neck pain, disability, and the psychological status of the patients with acute and chronic neck pain. Materials and methods: A total of 110 patients with neck pain were included in this study. Demographic and clinical characteristics of the patients were recorded. The lordosis angle was determined by the posterior tangent method. A visual analog scale (VAS), the Neck Disability Index (NDI), and the Hospital Anxiety and Depression (HAD) scale were administered to …
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Turkish Journal of Medical Sciences
Background/aim: Diabetic foot ulcers and related complications are a major cause of morbidity and hospital admissions. Our aim was to evaluate the risk factors associated with poor outcome in diabetic foot ulcers. Materials and methods: A prospective study was conducted on patients with diabetic foot ulceration attending the Madinah Teaching Hospital from June 2014 to December 2015. Potential risk factors and laboratory test results at presentation were recorded and their association with outcome (healing vs. amputation) was analyzed using IBM SPSS Statistics for Windows, Version 22.0. Results: In total, 112 patients were studied during our study period. The majority of …
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Turkish Journal of Medical Sciences
Background/aim: The distribution and the demographic, etiological, and clinical features of autoimmune bullous diseases (ABDs) vary according to geographic regions of the world. The limited number of reported studies in Turkey are mostly retrospective and generally include only pemphigus. The aim of our study was to evaluate the demographic data, clinical features, associated triggering factors, and comorbidities in patients newly diagnosed with ABDs. Materials and methods: In this descriptive and prospective study, the demographic data, inhabited regions, smoking and drinking habits, presence of comorbidities, and specific and general potential triggering factors of ABDs considered by the patients were examined. Furthermore, …
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate and determine the relationships (if any) among pain, depression levels, fatigue, sleep quality, and quality of life in patients with rheumatoid arthritis (RA) aged 65 years and over, and to compare the results with those of RA patients under 65 years of age. Materials and methods: The study included 52 patients with RA aged 65 years and over (Group 1) and 84 patients with RA under 65 years of age (Group 2). Pain, depression levels, fatigue, sleep quality, quality of life, and disease activity of all of the participants were evaluated …
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the efficacy of the Artcure Diffusional Patch, which contains a mixture of 6 herbal oils (oleum thymi, oleum limonis, oleum nigra, oleum rosmarini, oleum chamomilla, oleum lauriexpressum) and has a hypoosmolar lipid structure, in the conservative treatment of lumbar disc herniation patients and to show the advantages and/or possibility of using this as an alternative method to surgery. Materials and methods: Of the 120 patients enrolled, 79 clinically diagnosed patients were included in the study. Clinical evaluations were performed on patients who had findings of protrusion or extrusion in their magnetic …
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
Turkish Journal of Medical Sciences
Background/aim: Thoracic spine insufficiency is a subject of interest in neck problems. The aim was to investigate thoracic spinal curvature and mobility in subjects with and without chronic neck pain (CNP), cut-off points, and the relationship with pain. Materials and methods: Fifty-six patients with CNP (CNP group) and 53 healthy volunteers (control group) were included. Neck pain intensity of the patients was assessed by visual analogue scale and sagittal thoracic curvature and mobility of all participants were assessed by Spinal Mouse (Idiag, Fehraltorf, Switzerland). Results: Thoracic curvature was higher (P < 0.001) and mobility lower in the CNP group in comparison to the control group (P = 0.013). There was a positive correlation between pain intensity and thoracic curvature (r = 0.391, P < 0.001), while there was a negative correlation between pain intensity and thoracic mobility (r = -0.260, P = 0.006). For detecting neck pain, it was observed that the cut-off points for thoracic curvature and mobility were 45.5° and 30.0°, respectively. Conclusions: An increase in thoracic curvature of more than 45° and a decrease in mobility more than 30° may be critical for CNP patients.
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
Turkish Journal of Medical Sciences
Background/aim: This study aimed to describe the cultural adaptation of the Turkish Physical Activity Scale for the Elderly (PASE) and to examine the reliability and validity of the scale in older Turkish adults. Materials and methods: Eighty elderly people were recruited for the study. The assessments included the PASE, the International Physical Activity Questionnaire (IPAQ), the Short Physical Performance Battery and Short Form-36 Quality of Life Questionnaire (SF-36), and the Mini Mental State Test. Outcome measures were conducted twice within a week (test-retest) for reliability. Results: Cronbach's α coefficient was 0.714 for the initial evaluation. The intraclass correlation coefficient for …
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori is a pathogen that colonizes a majority of the world's population. Genetic diversity within the virulence genes of bacteria such as cagPAI and vacA may have a modified effect on the pathogenic potential of the bacteria. This study aimed to investigate which genes can be suggested as potentially related virulence factors for H. pylori-associated active chronic gastritis and stomach adenocarcinoma in the northwest of Iran and south of Turkey. Materials and methods: Formalin-fixed, paraffin-embedded stomach biopsy tissue samples were obtained from Iranian and Turkish patients from selected geographical regions. The prevalence of selected cagPAI genes and vacA …
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Turkish Journal of Medical Sciences
Background/aim: Increased airway resistance reduces the effectiveness of ventilation treatment. Endotracheal tubes (ETTs) and connectors contribute to resistance. However, the effect of a closed system suction (CSS) connector is not well known. We compared the in vivo resistance occurring with a CSS connector with that of the standard connector. Materials and methods: This prospective study was conducted at Gazi University Hospital's neonatal intensive care unit. Intubated neonates were studied for two cycles; each cycle contained two periods of ETT + connector pairs (15 min/period) as follows: cycle 1 [A: long ETT + standard connector; B: long ETT + CSS connector] …
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus (DM) is one of the most common metabolic diseases seen in the world today. Diabetic neuropathy (DN) is a chronic complication of the disease that is rarely reported in children, since it has a relatively longer latency period. Our main objective in this study is to determine the incidence rate of DN in pediatric DM patients and assess the risk factors associated with DN. Materials and methods: Data from 111 patients from January 2011 to May 2014 were reviewed in a retrospective manner. Nerve conduction studies were performed as the gold standard in diagnosis. Results: The incidence …
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
Turkish Journal of Medical Sciences
Background/aim: One of the factors that affect the occurrence of acne is the presence of Propionibacterium acnes. The present study was conducted to compare the culture and polymerase chain reaction (PCR) methods for identifying P. acnes in lesions isolated from patients with acne. Materials and methods: To examine the presence of P. acnes, 70 samples of acne lesions were collected. Microbial culture and the PCR molecular technique were used to identify P. acnes. Results: Of the total of 70 samples, 14 cases (20%) were identified as P. acnes positive using microbial culture and 58 cases (82.85%) using PCR. The results …
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Turkish Journal of Medical Sciences
Background/aim: IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS are mutations covering 76% of all the β-globin mutations in the Turkish population. In this study, our aim is to develop a reliable, fast, real-time kit for these mutations using the TaqMan probe method. Materials and methods: This study included 100 individuals with beta-thalassemia or sickle cell anemia who had unknown mutations, and 21 controls with known mutations. Results: We designed a kit containing the IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS …
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Turkish Journal of Medical Sciences
Background/aim: The objective of this study was to investigate and analyze the behavioral and neurochemical effects of monosodium glutamate (MSG) injections at various and subsequent dosages on male Wistar rats during the neonatal period. Materials and methods: In order to determine the behavioral and neurochemical effects of MSG, the experiment was implemented on neonatal male Wistar rats and the test was repeated for various MSG dosages. After completing the experiment, additionally, levels of dopamine, GABA, catecholamine (dopamine, noradrenaline, and adrenaline) and glutamate in the brain cells of the decapitated rats were also measured using the ELISA method. Results: Considering the …
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
Turkish Journal of Medical Sciences
Background/aim: Renal oxidative stress occurs in ureteral obstructions. The purpose of this study was to investigate the effect of the antioxidant and antiischemic agent trimetazidine (TMZ) on oxidative stress following ureteral obstruction. Materials and methods: Ten groups were established. Sham groups were checked as controls after 1 and 3 weeks. The other 8 groups had partial or complete ureteral obstruction while receiving or not receiving trimetazidine (TMZ) at 5 mg/kg daily and were evaluated after either 1 week or 3 weeks. Creatinine and cystatin C measurements were performed in the serum. Malondialdehyde, myeloperoxidase, catalase, and glutathione peroxidase activity were measured …
Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan
Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan
Turkish Journal of Medical Sciences
Background/aim: Our aim was to investigate the association of kinesiophobia with pain, quality of life, clinical measures, and depression in patients with ankylosing spondylitis (AS). Materials and methods: Patients with AS (n: 163) were enrolled in the study. Kinesiophobia was evaluated with the Tampa Scale of Kinesiophobia (TSK), pain with a visual analog scale (VAS), mobility with Bath Ankylosing Spondylitis Metrology Index (BASMI), disease activity with the Bath AS Disease Activity Index (BASDAI), functional status with the Bath AS Functional Index (BASFI), depression level with Beck's Depression Inventory (BDI), and quality of life with the AS Quality of Life Questionnaire …
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Turkish Journal of Medical Sciences
Background/aim: Colorectal adenomatous polyps are precursors of colorectal cancer (CRC), which can be prevented with surveillance colonoscopy. This study aimed to assess risk factors for the recurrence of colorectal polyps and CRC following polypectomy. Materials and methods: In this single-center trial, a total of 510 patients who applied to the endoscopy unit of Hacettepe University Hospital for various reasons and who were diagnosed with at least one colorectal adenomatous polyp between 2000 and 2010 were retrospectively analyzed. Patients with colorectal adenomatous polyps or CRC recurrences were examined in terms of clinical and histological risk factors. Results: A total of 190 …
The Effects Of The Number Of Physical Therapy Sessions On Pain, Disability,And Quality Of Life In Patients With Chronic Low Back Pain, Burcu Meti̇n Ökmen, Engi̇n Koyuncu, Bi̇lal Uysal, Neşe Özgi̇rgi̇n
The Effects Of The Number Of Physical Therapy Sessions On Pain, Disability,And Quality Of Life In Patients With Chronic Low Back Pain, Burcu Meti̇n Ökmen, Engi̇n Koyuncu, Bi̇lal Uysal, Neşe Özgi̇rgi̇n
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate and compare the effect of different physical therapy (PT) session numbers on pain, impairment. and quality of life in patients with chronic low back pain (LBP).Materials and methods: In this prospective, randomized-controlled, single-blind trial, a total of 60 patients with chronic LBP were divided into 2 groups with simple randomization within the scope of the study. A PT program of a total of 10 sessions was applied for patients in Group 10 (n = 30) and a total of 15 sessions for patients in Group 15 (n = 30). The main …