Female Urogenital Diseases and Pregnancy Complications Commons^™

The Role Of Misoprostol In The Reduction Of Maternal Deaths In Low Resource Settings: A Systematic Review With Recommendations For Action, Melissa Anne Mcmillian

Master of Public Health Program Student Publications

Objective: The purpose of this systematic review is to determine the role misoprostol currently plays in the reduction of maternal deaths and implications for the future reduction of maternal deaths in low resource settings.

Methods: A comprehensive review of the literature was performed using the following databases: The Cochrane Database, Ebsco, MEDLINE, PubMed, and Electronic Journal Center (EJC). Articles were excluded based upon date published, overt data changes since publication, and setting of misoprostol interventions in tertiary or referral centers that have access to oxytocin. A total of 61 articles were included from 2002-2012 and demonstrated several methodologies and study ...

Cost Utility Of Treatment Of Stress Urinary Incontinence, Emily Von Bargen, Danielle Patterson

Clinical and Translational Science Research Retreat

Objective: There are many possible treatment options for stress urinary incontinence. We sought to investigate the cost-utility of non-surgical versus surgical treatments.

Study Design: A decision analysis model was created to compare non-surgical and surgical treatment options for healthy women with stress urinary incontinence. Decision paths included conservative management, pelvic floor physical therapy, pelvic floor physical therapy with electrical stimulation, incontinence pessary and surgical treatment with a midurethral sling. A Markov model cohort analysis was performed with a cycle length of one year starting at age 45 with a lifetime horizon. Probabilities, success rates and utilities for health outcomes were ...

Understanding Health Utilities In Women With Urinary Incontinence, Danielle Patterson, Michael Flynn, Courtney Stachowski, Abraham Morse

Clinical and Translational Science Research Retreat

Objectives: The purpose of this study was to compare the health utility of UI in women as derived from the EQ-5D with the gold standard, the Standard Gamble. The secondary aim of this study was to compare health utility values of affected patients to healthy controls.

Materials and Methods: Clinical diagnosis was categorized as normal, stress, mixed or urge urinary incontinence. Healthy controls were read a scenario for stress or mixed UI. All subjects completed the Sandvik Severity Index (SSI), EQ-5D, and Standard Gamble (SG) conversation.

Results: 50 healthy controls and 119 affected subjects were recruited. The mean utility value ...