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Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. McManus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, Robert J. Goldberg 2018 University of Massachusetts Medical School

Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. Mcmanus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, Robert J. Goldberg

Open Access Articles

BACKGROUND: To examine age-specific differences in the frequency and impact of cardiac and non-cardiac conditions among patients aged 65years and older hospitalized with acute myocardial infarction (AMI).

METHODS: Study population consisted of 3863 adults hospitalized with AMI at 11 medical centers in central Massachusetts on a biennial basis between 2001 and 2011. The presence of 11 chronic conditions (five cardiac and six non-cardiac) was based on the review of hospital medical records.

RESULTS: Participants' median age was 79years, 49% were men, and had an average of three chronic conditions (average of cardiac conditions: 2.6 and average of non-cardiac conditions ...


Modeling In The Physiology Classroom, Sowmya Anjur 2018 Illinois Mathematics and Science Academy

Modeling In The Physiology Classroom, Sowmya Anjur

Faculty Publications & Research

Physiology and Disease is a Biology elective at IMSA that has been developed to be mostly student-centered. Some examples of student projects include modeling heart structure to reflect function and creating LED arduino monitors to measure heart rate. Students also measure their lung capacity and blood pressure to demonstrate correlation of these values with heart rate, and trace the correlation back to neuronal controls. Projects such as these integrate other disciplines such as engineering and conform to NGSS Science and Engineering standards and NGSS Cross cutting Concepts standards. Students take responsibility for their own learning and articulate better on tests.


Association Of Religiosity And Spirituality With Quality Of Life In Patients With Cardiovascular Disease: A Systematic Review, Hawa Abu, Christine M. Ulbricht, Eric Y. Ding, Jeroan J. Allison, Elena Salmoirago-Blotcher, Robert J. Goldberg, Catarina I. Kiefe 2018 University of Massachusetts Medical School

Association Of Religiosity And Spirituality With Quality Of Life In Patients With Cardiovascular Disease: A Systematic Review, Hawa Abu, Christine M. Ulbricht, Eric Y. Ding, Jeroan J. Allison, Elena Salmoirago-Blotcher, Robert J. Goldberg, Catarina I. Kiefe

Quantitative Health Sciences Publications and Presentations

Purpose: This review systematically identified and critically appraised the available literature that has examined the association between religiosity and/or spirituality (R/S) and quality of life (QOL) in patients with cardiovascular disease (CVD).

Methods: We searched several electronic online databases (PubMed, SCOPUS, PsycINFO, and CINAHL) from database inception until October 2017. Included articles were peer-reviewed, published in English, and quantitatively examined the association between R/S and QOL. We assessed the methodological quality of each included study.

Results: The 15 articles included were published between 2002 and 2017. Most studies were conducted in the US and enrolled patients with ...


Problems Experienced In The Second And Third Months After Discharge From A Heart Failure-Related Hospitalization, Joan S. Grant, Lucinda J. Graven 2018 University of Alabama at Birmingham School of Nursing

Problems Experienced In The Second And Third Months After Discharge From A Heart Failure-Related Hospitalization, Joan S. Grant, Lucinda J. Graven

Journal of Patient-Centered Research and Reviews

The purpose of this study was to identify high-priority problems experienced by individuals during the second and third month after discharge from an acute care facility for heart failure. This descriptive, exploratory study, an extension of a previous analysis that examined high-priority problems in the first month, comprised 19 participants who were assigned to an intervention group that received a randomized, 12-week-pilot coping partnership (COPE-HF) intervention. A trained research nurse provided the intervention, and participants used a standard list to identify high-priority heart failure-related problems. Quantitative and content data analysis was conducted. While the highest-priority problem continued to be managing ...


New-Onset Cardiomyopathy With And Without Atrial Fibrillation, Vinay Mehta, Alexander J. Albers, Alex Baek, Maharaj Singh 2018 Aurora BayCare Medical Center

New-Onset Cardiomyopathy With And Without Atrial Fibrillation, Vinay Mehta, Alexander J. Albers, Alex Baek, Maharaj Singh

Journal of Patient-Centered Research and Reviews

Background: Atrial fibrillation (AF) is the most common arrhythmia and is often associated with cardiomyopathy (CM) and heart failure. There has been little research performed to assess whether there are any differences in patient profile, comorbidities, presenting complaints, and electrocardiographic (ECG) or laboratory characteristics and outcomes between patients who have AF at presentation or preceding the diagnosis of new-onset CM (defined as left ventricular ejection fraction ≤ 40%) and patients who are diagnosed with new-onset CM without any preceding atrial dysrhythmias.

Purpose: To assess differences among patients with new-onset CM (LVEF ≤ 40%) with AF and without AF.

Methods: We used a ...


Differences In Metabolic Profile Between Right And Left Atria Of Patients With Atrial Fibrillation, Larisa Emelyanova, Steven M. Komas, Susan Olet, Sean Ryan, Catherine Warner, Farhan Rizvi, Gracious R. Ross, David C. Kress, Daniel P. O'Hair, Francis X. Downey 2018 Aurora Research Institute

Differences In Metabolic Profile Between Right And Left Atria Of Patients With Atrial Fibrillation, Larisa Emelyanova, Steven M. Komas, Susan Olet, Sean Ryan, Catherine Warner, Farhan Rizvi, Gracious R. Ross, David C. Kress, Daniel P. O'Hair, Francis X. Downey

Journal of Patient-Centered Research and Reviews

Background: Several studies have demonstrated genomic, morphological, and electrophysiological differences between the right atrium and left atrium, suggesting that dissimilar mechanisms may contribute to the development and progression of atrial fibrillation (AF). Therefore, differences in metabolic response to AF between atria are foreseeable. Given the complexity of AF development and progression, understanding AF-associated changes in metabolites in both atria will help in better clinical management of AF.

Purpose: To compare potential changes in metabolites in the right atrial (RAA) and left atrial (LAA) appendage tissue from patients with (AF+) and without (non-AF) history of AF.

Methods: RAA and LAA tissue ...


Heartqol Validation In Patients With Ischemic Heart Failure, Sara Walczak, Susan Olet, Christina Sauld, Deborah Waller, Nasir Z. Sulemanjee 2018 Aurora Research Institute

Heartqol Validation In Patients With Ischemic Heart Failure, Sara Walczak, Susan Olet, Christina Sauld, Deborah Waller, Nasir Z. Sulemanjee

Journal of Patient-Centered Research and Reviews

Background: Patient-reported outcome measures are increasingly used in clinical trials as performance measures to evaluate quality of care. Health-related quality of life is an example of a patient-reported outcome measure. The English version of the heart disease-specific HeartQoL health-related quality of life questionnaire has previously been validated in patients with heart disease.

Purpose: To validate the English version of the HeartQoL in patients with ischemic heart failure.

Methods: Patients with ischemic heart failure meeting clinical eligibility criteria and being treated at Aurora St. Luke’s Medical Center (Milwaukee, WI) completed a sociodemographic questionnaire, the HeartQoL, the 36-Item Short Form Health ...


Is Spontaneous Termination Of Atrial Fibrillation During Hybrid Ablation A Predictor Of Clinical Outcome In Patients With Persistent Atrial Fibrillation?, Lynn Erickson, David C. Kress, Firas Zahwe, Tadele Mengesha, David Krum, Jasbir S. Sra 2018 Aurora Research Institute

Is Spontaneous Termination Of Atrial Fibrillation During Hybrid Ablation A Predictor Of Clinical Outcome In Patients With Persistent Atrial Fibrillation?, Lynn Erickson, David C. Kress, Firas Zahwe, Tadele Mengesha, David Krum, Jasbir S. Sra

Journal of Patient-Centered Research and Reviews

Background: An epicardial/endocardial (hybrid) ablation approach has emerged as an option to treat a difficult population of patients with persistent atrial fibrillation (AF). Limited information exists on the importance of AF termination as a predictor of clinical outcome during hybrid ablation.

Purpose: This retrospective study aimed to demonstrate the significance of spontaneous AF termination during hybrid ablation of persistent AF.

Methods: We studied results from 63 consecutive hybrid ablations in patients with no prior ablation, a mean (± standard deviation) persistent AF duration of 19 ± 16 months and a mean follow-up of 27 ± 13 months. Patients received both epicardial ablation ...


Unhealthy Lifestyle And The Risk Of Metabolic Syndrome- The Romanian Experience, Angela Cozma, Adela Sitar-Taut, Laura Urian, Adriana Fodor, Ramona Suharoschi, Crina Muresan, Vasile Negrean, Dorel Sampelean, Dumitru Zdrenghea, Dana Pop, Leucuta Daniel, Olga Hilda Orasan 2018 Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 4 th Department of Internal Medicine, Cluj-Napoca, Romania

Unhealthy Lifestyle And The Risk Of Metabolic Syndrome- The Romanian Experience, Angela Cozma, Adela Sitar-Taut, Laura Urian, Adriana Fodor, Ramona Suharoschi, Crina Muresan, Vasile Negrean, Dorel Sampelean, Dumitru Zdrenghea, Dana Pop, Leucuta Daniel, Olga Hilda Orasan

Journal of Mind and Medical Sciences

Background. Metabolic syndrome (MetS) represents a clustering of metabolic risk factors for cardiovascular disease. Many studies have shown the influence of an unhealthy lifestyle on the risk of MetS, yet some aspects remain controversial. Aim of the study: to investigate the relationship between an unhealthy lifestyle and the risk of MetS.

Materials and Methods. The study was conducted using a sample of 181 patients, 54 (29.8%) males and 127 (70.2%) females, aged 59.95±10.8 years. The baseline survey involved the completion of structured questionnaires and clinical examination.

Results. Rural environment, lower education level, past smoking, the ...


De-Airing Method Of An Axial Flow Left Ventricular Assist Device Influences Post-Operative Lactate Dehydrogenase Levels: A Possible Explanation For Some Episodes Of Pump Thrombosis, Daizo Tanaka, Saif Rizvi, Andrew Boyle, MD, John W..C. Entwistle 2018 Thomas Jefferson University

De-Airing Method Of An Axial Flow Left Ventricular Assist Device Influences Post-Operative Lactate Dehydrogenase Levels: A Possible Explanation For Some Episodes Of Pump Thrombosis, Daizo Tanaka, Saif Rizvi, Andrew Boyle, Md, John W..C. Entwistle

The VAD Journal

Background

Pump thrombosis (PT) is a relatively uncommon but serious complication of a left ventricular assist device (LVAD). We believe that de-airing of the HeartMate II (HMII) with the pump turned on and a clamp across the outflow graft may lead to early thrombus formation due to heat generation on the bearings.

Methods

Patients who underwent HMII implantation from November 2012 to February 2016 were retrospectively reviewed. Patients were separated into two groups depending on the timing of removing the clamp from the outflow graft. Patients in Group 1 underwent de-airing by turning on the pump with the vascular clamp ...


The Epidemiology Of Infective Endocarditis Among People Who Inject Drugs In London, Ontario., Brian Hallam 2018 The University of Western Ontario

The Epidemiology Of Infective Endocarditis Among People Who Inject Drugs In London, Ontario., Brian Hallam

Electronic Thesis and Dissertation Repository

Infective endocarditis is an infectious disease that affects the valves of the heart. Injection drug use is currently a leading risk factor among patients with endocarditis. We conducted a prospective study using data from hospital chart records among patients with endocarditis in London, Ontario, which has a relatively high prevalence of people who inject drugs to assess the severity of the issue and the major risk factors of mortality pertaining to this population. This study had a sample size of 353 and included a review of the incidence of admissions of endocarditis, as well as a survival analysis, using both ...


Predictors Of Patient Activation At Acs Hospital Discharge And Health Care Utilization In The Subsequent Year, Rebecca L. Kinney 2018 University of Massachusetts Medical School

Predictors Of Patient Activation At Acs Hospital Discharge And Health Care Utilization In The Subsequent Year, Rebecca L. Kinney

GSBS Dissertations and Theses

Background. AHA guidelines have been established to reduce Acute Coronary Syndrome (ACS)-related morbidity, mortality and recurrent events post-discharge. These recommendations emphasize the patient as an engaged member of the health care team in secondary prevention efforts. Patients with high levels of activation are more likely to perform activities that will promote their own health and are more likely to have their health care needs met. Despite evidence and strong expert consensus supporting patients as active collaborators in their own ACS care, the complexity and unexpected realities of self-managing one’s care at home are often underestimated. This study seeks ...


Effects Of Reproductive Period Duration And Number Of Pregnancies On Midlife Ecg Indices: A Secondary Analysis From The Women's Health Initiative Clinical Trial, Nisha I. Parikh, Kristopher Kapphahn, Haley Hedlin, Jeffrey E. Olgin, Matthew A. Allison, Jared W. Magnani, Kelli R. Ryckman, Molly E. Waring, Marco Valentin Perez, Barbara V. Howard 2018 University of California, San Francisco

Effects Of Reproductive Period Duration And Number Of Pregnancies On Midlife Ecg Indices: A Secondary Analysis From The Women's Health Initiative Clinical Trial, Nisha I. Parikh, Kristopher Kapphahn, Haley Hedlin, Jeffrey E. Olgin, Matthew A. Allison, Jared W. Magnani, Kelli R. Ryckman, Molly E. Waring, Marco Valentin Perez, Barbara V. Howard

Open Access Articles

OBJECTIVES: Pregnancy, menses and menopause are related to fluctuations in endogenous sex hormones in women, which cumulatively may alter cardiac electrical conduction. Therefore, we sought to study the association between number of pregnancies and reproductive period duration (RD, time from menarche to menopause) with ECG intervals in the Women's Health Initiative Clinical Trials.

DESIGN: Secondary analysis of multicentre clinical trial.

SETTING: USA.

PRIMARY OUTCOME MEASURES: ECGintervals: PR interval, P-wave duration, P-wave dispersion, QTc interval.

PARTICIPANTS: n=40 687 women (mean age=62 years) participating in the Women's Health Initiative Clinical Trials. 82.5% were white, 9.3% black ...


Application Of Photovoice With Focus Groups To Explore Dietary Behaviors Of Older Filipino Adults With Cardiovascular Disease, Jane Jih, Trish La Chica, Luisa M. Antonio, Ofelia O. Villero, Mary N. Roque, Joseph R. Domingo, Joshua F. Landicho, Anna M. Napoles, Celia P. Kaplan, Tung T. Nguyen 2018 University of California San Francisco

Application Of Photovoice With Focus Groups To Explore Dietary Behaviors Of Older Filipino Adults With Cardiovascular Disease, Jane Jih, Trish La Chica, Luisa M. Antonio, Ofelia O. Villero, Mary N. Roque, Joseph R. Domingo, Joshua F. Landicho, Anna M. Napoles, Celia P. Kaplan, Tung T. Nguyen

Journal of Health Disparities Research and Practice

Filipino Americans have high rates of cardiovascular diseases (CVD). This study explored the dietary behaviors, a modifiable risk factor, of Filipinos with CVD. Filipinos with CVD were recruited and trained to do Photovoice. Participants took photos to depict their “food experience,” defined as their daily dietary activities. Participants then shared their photos during focus groups. Focus group transcripts were analyzed using an iterative, grounded theory approach. Among 38 Filipino participants, the mean age was 70 years old and all were foreign-born. Major themes included efforts to retain connection to Filipino culture through food, and dietary habits shaped by cultural health ...


Blood Pressure And Job Domains Among Hotel Housekeepers, Marie-Anne Sanon Rosemberg PhD, MN, RN, Bidisha Ghosh Ms., John Shaver BSN, Maria Militzer MA, Julia Seng PhD, CNM, FAAN, Marjorie C. McCullagh PhD, RN, APHN-BC, COHN-S, FAAOHN, FAAN 2018 University of Michigan

Blood Pressure And Job Domains Among Hotel Housekeepers, Marie-Anne Sanon Rosemberg Phd, Mn, Rn, Bidisha Ghosh Ms., John Shaver Bsn, Maria Militzer Ma, Julia Seng Phd, Cnm, Faan, Marjorie C. Mccullagh Phd, Rn, Aphn-Bc, Cohn-S, Faaohn, Faan

Journal of Health Disparities Research and Practice

Hotel housekeepers have challenging working conditions, putting them at risk for poor health such as hypertension. Despite their risks, few studies have measured their blood pressure (BP). The purpose of this study was to explore hotel housekeepers’ blood pressure and the associations between work and BP. Methods: A community engagement approach was used to recruit study participants. Data sources included questionnaires, and BP measurement. Results: Over 25% of the 39 hotel housekeepers reported hypertension diagnosis and/or antihypertensive medication used. Across the job domains, job satisfaction was correlated with diastolic BP, and workload was correlated with systolic BP. There were ...


Safety And Efficacy Of Routine Bridging Anticoagulation For Subtherapeutic Anticoagulation In Outpatients With A Left Ventricular Assist Device, David C. Shisler, Gaurang N. Vaidya, Lori Muncy, Rajakrishnan Vijayakrishnan, Mark S. Slaughter, Emma J. Birks, Dmitry Abramov 2018 University of Louisville

Safety And Efficacy Of Routine Bridging Anticoagulation For Subtherapeutic Anticoagulation In Outpatients With A Left Ventricular Assist Device, David C. Shisler, Gaurang N. Vaidya, Lori Muncy, Rajakrishnan Vijayakrishnan, Mark S. Slaughter, Emma J. Birks, Dmitry Abramov

The VAD Journal

Background

Anticoagulation with vitamin K antagonists is vital to prevent pump thrombosis in patients with left ventricular assist devices (LVADs). However, the safety and efficacy of bridging anticoagulation for the routine management of subtherapeutic international normalized ratio (INR) in stable outpatients remains poorly characterized.

Methods

In this retrospective study, a total of 60 LVAD outpatients had 110 episodes of subtherapeutic INR noted on routine testing. 34 of these episodes were managed with parenteral bridging anticoagulation and 76 were managed with only an adjusted dose of warfarin. The rates of bleeding and thromboembolic adverse events following these episodes of subtherapeutic INR ...


Cardiac Autonomic Neuropathy In Diabetes: A Predictor Of Cardiometabolic Events, Aaron I. Vinik, Carolina Casellini, Henri K. Parson, Sheri R. Colberg, Marie-laure Nevoret 2018 Old Dominion University

Cardiac Autonomic Neuropathy In Diabetes: A Predictor Of Cardiometabolic Events, Aaron I. Vinik, Carolina Casellini, Henri K. Parson, Sheri R. Colberg, Marie-Laure Nevoret

Human Movement Sciences Faculty Publications

Autonomic nervous system (ANS) imbalance manifesting as cardiac autonomic neuropathy in the diabetic population is an important predictor of cardiovascular events. Symptoms and signs of ANS dysfunction, such as resting heart rate elevations, diminished blood pressure responses to standing, and altered time and frequency domain measures of heart rate variability in response to deep breathing, standing, and the Valsalva maneuver, should be elicited from all patients with diabetes and prediabetes. With the recognition of the presence of ANS imbalance or for its prevention, a rigorous regime should be implemented with lifestyle modification, physical activity, and cautious use of medications that ...


Coronary Artery Calcium Scores In Public Safety Personnel, Nirupama Devanathan, Mark O'Shaughnessy MD 2018 Parkview Health

Coronary Artery Calcium Scores In Public Safety Personnel, Nirupama Devanathan, Mark O'Shaughnessy Md

MAHE Student Research

Background: Occupational research has demonstrated that public safety personnel are prone to death by adverse cardiovascular events that are precipitated by on-the-job physiological stressors; the presence of occult coronary artery disease further increases this risk. It has been reported in literature that there is interest from public safety personnel in screening programs that could lead to counseling for possible lifestyle modifications to promote cardiovascular wellness. Objective: At present, there are limited guidelines to screen for occult coronary artery disease among public safety personnel, which include firefighters, police officers, and Emergency Medical Service (EMS) workers. The goal of this study is ...


Parkview Heart Institute (Phi) Postoperative Atrial Fibrillation (Poaf) In Coronary Artery Bypass (Cabg) And Aortic Valve Replacement (Avr) Surgery: A Chart Review, Joshuah Caccamo, Daniel Filler, Douglas Gray MD, Michael J Mirro MD 2018 Parkview Health

Parkview Heart Institute (Phi) Postoperative Atrial Fibrillation (Poaf) In Coronary Artery Bypass (Cabg) And Aortic Valve Replacement (Avr) Surgery: A Chart Review, Joshuah Caccamo, Daniel Filler, Douglas Gray Md, Michael J Mirro Md

MAHE Student Research

Background: Post-operative Atrial fibrillation (POAF) is a common complication associated with cardiac operations, and it occurs due to a lack of coordination of atrial depolarization, so the AV node fires as soon as its refractory period ends. Major consequences include clot formation, stroke, and other post-operative complications. The prevalence rate of POAF is 30 to 40%, while a combined CABG and AVR procedure is as high as 60%. Patient specific factors like medical history can also indicate predictors for POAF, but age has been the most widely accepted predictor. Objective: Postoperative atrial fibrillation has proven to be a prevalent complication ...


Parkview Heart Institute Telecardiology Consultation Service (Phi-Tcs) Outcomes, Roy Robertson MD, Srilatha Dasari, George Sun 2018 Parkview Health

Parkview Heart Institute Telecardiology Consultation Service (Phi-Tcs) Outcomes, Roy Robertson Md, Srilatha Dasari, George Sun

MAHE Student Research

Background: Cardiovascular disease is a major cause of death in the United States, and there is a growing shortage of physician specialists necessary to address this issue. Telecardiology is a form of telemedicine that allows cardiologists to treat patients from remote locations, and this form of patient care has the potential to improve both patient and economic outcomes, as well as reduce the length of patient hospitalization. The PHI-TCS was established at Parkview Huntington Hospital in September 2016 and has since been extended to additional Parkview community hospitals.

Objective: Our objectives in this study were to evaluate the usage patterns ...


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