Albany State University, Georgia
University of Pennsylvania
Liberty University
Aga Khan University
James Madison University
Otterbein University
Department of Neurology, University of Pécs, Hungary
Iowa State University
Oscillation In Mathematical Epidemiology,
2019
Bates College
Oscillation In Mathematical Epidemiology, Meredith Greer
Annual Symposium on Biomathematics and Ecology: Education and Research
No abstract provided.
Multidisciplinary Education And Research In Biomathematics For Solving Global Challenges,
2019
Illinois State University
Multidisciplinary Education And Research In Biomathematics For Solving Global Challenges, Padmanabhan Seshaiyer
Annual Symposium on Biomathematics and Ecology: Education and Research
No abstract provided.
Immunosuppressive Treatment And The Risk Of Diabetes In Rheumatoid Arthritis,
2019
Diakonhjemmet Hospital
Immunosuppressive Treatment And The Risk Of Diabetes In Rheumatoid Arthritis, Siri Lillegraven, Jeffrey D. Greenberg, George W. Reed, Katherine Saunders, Jeffrey R. Curtis, Leslie R. Harrold, Marc C. Hochberg, Dimitrios A. Pappas, Joel M. Kremer, Daniel H. Solomon
Leslie R. Harrold
OBJECTIVE: Inflammation and anti-inflammatory treatments might influence the risk of diabetes. The objective of this study was to assess factors associated with incident diabetes in rheumatoid arthritis (RA).
METHODS: The study population consisted of RA patients from a multi-center cohort study, Corrona. To assess risk associated with disease modifying antirheumatic drug (DMARD) exposure, we assessed five mutually exclusive DMARD groups. Additionally, we assessed the risk associated with body mass index (BMI, < 25, 25-30, > 30 kg/m2) and glucocorticoid usage. Incident cases of diabetes were confirmed through adjudication, and Cox regression models were fit to estimate the risk of incident diabetes.
RESULTS: We ...
Successful Extracorporeal Membrane Oxygenation In The Management Of Acute Respiratory Distress Syndrome And Cardiopulmonary Collapse Secondary To Amniotic Fluid Embolism,
2019
Rochester General Hospital
Successful Extracorporeal Membrane Oxygenation In The Management Of Acute Respiratory Distress Syndrome And Cardiopulmonary Collapse Secondary To Amniotic Fluid Embolism, Sumon Roy, Nishit A. Biniwale, Venkata S. Pendela, Patricia Oates, Katrina Wojciechowski, Scott C. Feitell
The VAD Journal
Amniotic fluid embolism (AFE) is one of the most devastating complications of pregnancy that typically manifests as acute cardiopulmonary collapse during delivery or in the postpartum period. The potential role of extracorporeal membrane oxygenation (ECMO) as a management technique in severe cases of AFE remains largely unknown given the limited literature available. In this report, we present the first case, to our knowledge, of successful implementation of ECMO as a life-saving measure in a case of hemorrhagic shock due to postpartum bleeding complicated by severe AFE leading to acute respiratory distress syndrome (ARDS) ultimately requiring tracheostomy. Hemodynamic decompensation is often ...
Systematic Literature Review Of Quetiapine For The Treatment Of Psychosis In Patients With Parkinsonism,
2019
American University of Health Sciences
Systematic Literature Review Of Quetiapine For The Treatment Of Psychosis In Patients With Parkinsonism, Jack J. Chen, Henry Hua, Lilian Massihi, Ivan Portillo, Azita Alipour, William Ondo, Khashayar Dashtipour
Library Articles and Research
Objective:
The purpose of this article was to determine the efficacy and tolerability of quetiapine compared with placebo or other interventions for psychosis in parkinsonism.
Methods:
Participants with a diagnosis of parkinsonism participated in randomized controlled trials (RCTs) investigating the efficacy and tolerability of quetiapine for psychotic symptoms within a defined follow-up period. The authors conducted searches on PubMed, Cochrane Controlled Register of Trials, and EMBASE for articles published from January 1991 to October 2017. Study methodology and patient- and treatment-level data were independently extracted and summarized by using descriptive statistics. Studies underwent quality assessment for risk of bias.
Results ...
The Immune Cell Infiltrate Populating Meningiomas Is Composed Of Mature, Antigen-Experienced T And B Cells,
2019
Hofstra Northwell School of Medicine
The Immune Cell Infiltrate Populating Meningiomas Is Composed Of Mature, Antigen-Experienced T And B Cells, L. Fang, D. E. Lowther, M. L. Meizlish, R. C. Anderson, J. N. Bruce, J. N. Stern, G. Yaari, L. Lovato, K. M. Cronk, K. C. O'Connor
Joel N.H. Stern
BACKGROUND: Meningiomas often harbor an immune cell infiltrate that can include substantial numbers of T and B cells. However, their phenotype and characteristics remain undefined. To gain a deeper understanding of the T and B cell repertoire in this tumor, we characterized the immune infiltrate of 28 resected meningiomas representing all grades. METHODS: Immunohistochemistry was used to grossly characterize and enumerate infiltrating lymphocytes. A molecular analysis of the immunoglobulin variable region of tumor-infiltrating B cells was used to characterize their antigen experience. Flow cytometry of fresh tissue homogenate and paired peripheral blood lymphocytes was used to identify T cell phenotypes ...
Treating Latent Tuberculosis Infection In Newly Arriving Refugees: An Advanced Practice Nurse Initiative At The University Of Louisville Global Health Center,
2019
University of Louisville
Treating Latent Tuberculosis Infection In Newly Arriving Refugees: An Advanced Practice Nurse Initiative At The University Of Louisville Global Health Center, Linda Goss, Dawn Balcom, Karen Mutsch, Ruth Carrico, Rahel Bosson
Journal of Refugee & Global Health
Background: A review of newly arriving refugees referred to the local health department for latent tuberculosis infection (LTBI) treatment during 2013-2015 revealed a treatment gap of 73%, supporting the need to identify new approaches to treat vulnerable populations and mirrored results in the literature.
Objectives: 1) Describe an advanced practice registered nurse (APRN) led alternative approach to LTBI treatment in the refugee population; and 2) evaluate the impact of a 12-week regimen for LTBI on treatment acceptance, adherence and completion.
Methods: During the initial health screening visit, treatment options were provided for those identified with LTBI consisting of either a ...
Gait Alterations In Peripheral Arterial Disease Are Not Worsened By The Presence Of Diabetes,
2019
University of Nebraska at Omaha
Gait Alterations In Peripheral Arterial Disease Are Not Worsened By The Presence Of Diabetes, Hafizur Rahman
Student Research and Creative Activity Fair
Peripheral arterial disease (PAD) is a vascular disease where atherosclerotic blockages restrict blood flow to muscles in the lower extremities. Diabetes is a common co-morbid condition in PAD and has been shown to increase the risk of lower extremity amputation compared to PAD without diabetes. Although there is a clear pathological relationship between diabetes and PAD, the gait mechanics involved remain indistinct. Therefore, the purpose of this study was to determine whether the presence of diabetes in addition to PAD results in greater functional impairment during ambulation. Twenty-three subjects with PAD and twelve controls consented to participate in the research ...
The Effects Of A 12-Week Jump Rope Exercise Program On Abdominal Adiposity, Vasoactive Substances, Inflammation & Vascular Function In Prehypertensive Adolescent Girls,
2019
University of Nebraska at Omaha
The Effects Of A 12-Week Jump Rope Exercise Program On Abdominal Adiposity, Vasoactive Substances, Inflammation & Vascular Function In Prehypertensive Adolescent Girls, Ronald Headid
Student Research and Creative Activity Fair
Childhood obesity is strongly associated with cardiovascular disease (CVD) development. It is necessary to combat unfavorable outcomes of obesity at a young age by utilizing effective interventions, such as exercise. Purpose: We sought to examine the effects of a jump rope exercise program on CVD risk factors, including body composition, vasoactive substances, inflammation, and vascular function in prehypertensive adolescent girls. Methods: Forty girls (age 14-16) were recruited and randomly assigned to a jump rope exercise group (EX, n=20) or control group (CON, n=20). Body composition, nitrate and nitrite levels, endothelin-1 (ET-1), c-reactive protein (CRP), systolic blood pressure and ...
The Effects Of Swimming Training On Arterial Stiffness, Muscular Strength And Cardiorespiratory Endurance In Postmenopausal Women With Stage 2 Hypertension,
2019
University of Nebraska at Omaha
The Effects Of Swimming Training On Arterial Stiffness, Muscular Strength And Cardiorespiratory Endurance In Postmenopausal Women With Stage 2 Hypertension, Steven Scott
Student Research and Creative Activity Fair
Objective:
Aging is associated with progressive decreases in arterial health and function as well as overall fitness. It is crucial to prevent or reduce the negative effects of aging on vasculature and fitness components by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a swimming (SWM) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx), muscle strength and aerobic capacity in postmenopausal women with stage 2 hypertension.
Methods:
Using a parallel experimental design, participants were randomly assigned to either a SWM (n=52) or non-exercising control group (n=48) for ...
Large Scale Dynamical Model Of Macrophage/Hiv Interactions,
2019
University of Nebraska at Omaha
Large Scale Dynamical Model Of Macrophage/Hiv Interactions, Sean T. Bresnahan, Matthew M. Froid
Student Research and Creative Activity Fair
Properties emerge from the dynamics of large-scale molecular networks that are not discernible at the individual gene or protein level. Mathematical models - such as probabilistic Boolean networks - of molecular systems offer a deeper insight into how these emergent properties arise. Here, we introduce a non-linear, deterministic Boolean model of protein, gene, and chemical interactions in human macrophage cells during HIV infection. Our model is composed of 713 nodes with 1583 interactions between nodes and is responsive to 38 different inputs including signaling molecules, bacteria, viruses, and HIV viral particles. Additionally, the model accurately simulates the dynamics of over 50 different ...
Impacts Of Dietary Nitrate On Endothelial Function, Arterial Stiffness, And Systemic Vascular Pressure In Peripheral Arterial Disease,
2019
University of Nebraska at Omaha
Impacts Of Dietary Nitrate On Endothelial Function, Arterial Stiffness, And Systemic Vascular Pressure In Peripheral Arterial Disease, Elizabeth J. Pekas, Steven D. Scott, Ronald J. Headid Iii, Michael D. Shukis, Jeonghwa Shin, Jiwon Song, Song-Young Park
Student Research and Creative Activity Fair
Peripheral arterial disease (PAD) is the manifestation of atherosclerotic plaque in the larger arteries of the legs, which results in impaired blood flow to the lower extremities. Markers of vascular health, including endothelial function and arterial stiffness, have been shown to be attenuated in PAD.
Purpose: We sought to examine the effects of a nitrate supplement (body mass-normalized dosage of beetroot juice) on vascular function measurements such as endothelial function, arterial stiffness, and central and peripheral blood pressure in patients with PAD. We hypothesized that acute intake of a nitrate supplement would improve vascular function.
Methods: PAD patients (stage II-III ...
Paleolithic Ketogenic Diet (Pkd) In Chronic Diseases: Clinical And Research Data,
2019
International Center for Medical Nutritional Intervention (ICMNI) – Paleomedicina Hungary
Paleolithic Ketogenic Diet (Pkd) In Chronic Diseases: Clinical And Research Data, Zsófia Clemens, Csaba Tóth
Journal of Evolution and Health
No abstract provided.
The Purification Of Human Adult Progenitor Cell Types To Promote Angiogenesis,
2019
The University of Western Ontario
The Purification Of Human Adult Progenitor Cell Types To Promote Angiogenesis, Stephen E. Sherman
Electronic Thesis and Dissertation Repository
Cellular transplantation strategies have aimed to combat critical limb ischemia (CLI) by inducing endogenous blood vessel regeneration. Transplantation of mesenchymal stromal cells (MSC) for CLI has proven safe and well-tolerated but demonstrated only modestly improved clinical outcomes explained in part by a lack of MSC survival and/or potency in ischemic tissues. This thesis focuses on the development of improved transplantation strategies for patients with CLI utilizing purified pro-angiogenic subsets of MSC and endothelial colony forming cells (ECFC) seeded within decellularized adipose tissue (DAT) bioscaffolds. First, I investigated whether purification of bone marrow-derived MSC based on a conserved stem cell ...
No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report,
2019
University of Massachusetts Medical School
No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report, Lauren M. Hall, Julia Reilly, Mathew J. Most, Jennifer Baima
Orthopedics and Physical Rehabilitation Publications and Presentations
Background: Cancer rehabilitation is a rapidly growing diverse field in physiatry. This case provides an example where rehabilitation physiatrists played a crucial role in the pain management, education, and rehabilitation before and after a palliative amputation. Due to her limited resources, both in her home country and in her local community, she could not access appropriate care that may have prevented the need for amputation. Though amputation is not generally accepted as the first line of treatment for pain, there have been several reports of palliative amputation in metastatic cancer patients. In particular, fore quarter amputations have been reported in ...
Diabetic Neuropathic Foot Without Neuropathy: Could It Be Cancer? - A Case Report,
2019
University of Massachusetts Medical School
Diabetic Neuropathic Foot Without Neuropathy: Could It Be Cancer? - A Case Report, Jennifer Baima, Felix Santiago, Mathew J. Most
Orthopedics and Physical Rehabilitation Publications and Presentations
We present a case of a 64 year-old diabetic male who presented with months of progressively worsening foot pain and swelling, who was initially diagnosed with Charcot joint disease.(CJD) He was ultimately found to have a very rare tumor.
Social Ecological Predictors Of Risky Sexual Behavior Among Young Adults,
2019
Saginaw Valley State University
Social Ecological Predictors Of Risky Sexual Behavior Among Young Adults, Maureen Muchimba
Journal of Social, Behavioral, and Health Sciences
Most studies on sexual behavior outcomes are restricted to adolescents. However, rates of sexually transmitted diseases (STDs) are highest among young adults. This study examined social–ecological predictors in adolescence that predict risky sexual behavior in young adulthood. Using longitudinal data, logistic regression was used to determine social–ecological factors that predict early sexual debut and a high number of lifetime sexual partners among 3,109 young adults. Risk-taking was associated with early sexual debut and a high number of lifetime sexual partners. Father–child connectedness decreased the odds of early sexual debut and a high number of lifetime sexual ...
Traditional And Nontraditional Risks For Kidney Disease: A Comparison Of Western And Paleolithic-Type Diets, Lynda Frassetto
Journal of Evolution and Health
No abstract provided.
Health Literacy And Type 2 Diabetes In Barbados,
2019
University of Phoenix
Health Literacy And Type 2 Diabetes In Barbados, Coralene Quimby-Worrell
The Qualitative Report
IIn this qualitative instrumental single case study, I explored how patients living with Type 2 diabetes (T2D) in Barbados manage the disease and what role health literacy might play. Purposeful sampling aided in selecting the sample for the study. The sample was 23 participants who were 40 years and older, diagnosed with T2D, living in Barbados, and attending the Endocrine Center for treatment. Participants responded to 13 open ended questions used to answer the research questions. Information was coded using NVivo 10 software and the software provided the themes based on the participants’ responses to the interview questions. The ...
Innovation And Competition In Advanced Therapy Medicinal Products,
2019
Chapman University
Innovation And Competition In Advanced Therapy Medicinal Products, Enrique Seoane-Vazquez, Vaishali Shukla, Rosa Rodriguez-Monguio
Pharmacy Faculty Articles and Research
"Advanced therapy medicinal products (ATMPs), including gene therapy, cell therapy, and tissue engineering products, represent a paradigm shift in health care as they have great potential for preventing and treating many diseases (Food and Drug Administration (FDA), 2013). By way of example, only 367 (8.0%) of the 4,603 rare diseases and conditions listed by the NIH Genetic and Rare Diseases Information Center had at least one FDA-approved drug therapy in early 2018. An estimated 3,038 (66.0%) of those rare diseases and conditions are congenital and genetic diseases that could potentially be treated by gene therapy. There ...
