Albany State University, Georgia
University of Pennsylvania
Liberty University
Aga Khan University
James Madison University
Otterbein University
Iowa State University
Atypical Presentation Of Obstructed Hemivagina And Ipsilateral Renal Anomaly,
2018
George Washington University
Atypical Presentation Of Obstructed Hemivagina And Ipsilateral Renal Anomaly, Christopher Grant, Christopher E. Bayne, N. Kern, Craig A. Peters
Urology Faculty Publications
Herlyn-Werner-Wunderlich Syndrome, otherwise known as obstructed hemivagina and ipsilateral renal anomaly (OHVIRA), is a rare Müllerian anomalyconsisting of uterine didelphys, hemivaginal septum, and ipsilateral renal agenesis. Patients often present at the onset of menarche with abdominal pain and a pelvic mass from an obstructed hemivagina. We report a child who presented with a febrile urinary tract infection and upon further workup was found to have OHVIRA.
A Rationally Engineered Capsid Variant Of Aav9 For Systemic Cns-Directed And Peripheral Tissue-Detargeted Gene Delivery In Neonates,
2018
University of Massachusetts Medical School
A Rationally Engineered Capsid Variant Of Aav9 For Systemic Cns-Directed And Peripheral Tissue-Detargeted Gene Delivery In Neonates, Dan Wang, Shaoyong Li, Dominic J. Gessler, Jun Xie, Li Zhong, Jia Li, Karen Tran, Kim Van Vliet, Lingzhi Ren, Qin Su, Ran He, Jason E. Goetzmann, Terence R. Flotte, Mavis Agbandje-Mckenna, Guangping Gao
Open Access Articles
Adeno-associated virus (AAV) has provided the gene therapy field with the most powerful in vivo gene delivery vector to realize safe, efficacious, and sustainable therapeutic gene expression. Because many clinically relevant properties of AAV-based vectors are governed by the capsid, much research effort has been devoted to the development of AAV capsids for desired features. Here, we combine AAV capsid discovery from nature and rational engineering to report an AAV9 capsid variant, designated as AAV9.HR, which retains AAV9's capability to traverse the blood-brain barrier and transduce neurons. This variant shows reduced transduction in peripheral tissues when delivered through ...
Www.Cd-Genomics.Com,
2018
University of California, San Francisco
Doacs Least Harmful For Patients With Calciphylaxis On Hemodialysis Needing Anticoagulation,
2018
Wayne State University School of Medicine
Doacs Least Harmful For Patients With Calciphylaxis On Hemodialysis Needing Anticoagulation, Mona Fayad
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of King BJ, El-Azhary RA, Mcevoy MT, et al. Direct oral anticoagulant medications in calciphylaxis. International Journal of Dermatology. 30 August 2017;56(1):1065-1070. doi: 10.1111/ijd.13685
Phytobiological Warfare: An Evolutionary Approach To Botanical Medicine,
2018
Southwest College of Naturopathic Medicine
Phytobiological Warfare: An Evolutionary Approach To Botanical Medicine, Guillermo Ruiz Nmd, Tiffany Turner, Jeffrey Langland
Journal of Evolution and Health
No abstract provided.
Identification Of Oral Clefts As A Risk Factor For Hearing Loss During Newborn Hearing Screening,
2018
University of Washington
Identification Of Oral Clefts As A Risk Factor For Hearing Loss During Newborn Hearing Screening, Patricia L. Purcell, Kathleen Cy Sie, Todd C. Edwards, Debra Lochner Doyle, Karin Neidt
Journal of Early Hearing Detection and Intervention
Objective: This study assessed whether children with oral clefts are appropriately classified as at-risk for hearing loss at the time of newborn hearing screening and describes their screening and diagnostic results.
Design: Birth certificates were used to identify children with cleft lip and palate or isolated cleft palate born in Washington State from 2008–2013. These were cross-referenced with the state’s Early Hearing Detection, Diagnosis and Intervention (EHDDI) database. Multivariate logistic regression was used to examine associations.
Results: Birth records identified 235 children with cleft lip and palate and 116 with isolated cleft palate. Six children were listed as ...
Modeling The Influenza Virus Infection In A Host: Consideration Of Semi-Infectious Particles,
2018
North Carolina State University at Raleigh
Modeling The Influenza Virus Infection In A Host: Consideration Of Semi-Infectious Particles, Alex P. Farrell, Ruian Ke
Biology and Medicine Through Mathematics Conference
No abstract provided.
Human Papillomavirus: The Influence Of Prevention And Vaccination,
2018
Eastern Kentucky University
Human Papillomavirus: The Influence Of Prevention And Vaccination, Lacey N. Russell
Kentucky Journal of Undergraduate Scholarship
Human Papillomavirus infections (HPV) are the most common sexually transmitted diseases in the United States. Of cancers in parts of the body where HPV is often discovered about 80% originated from an HPV infection. Despite this knowledge and the effectiveness of the HPV vaccine, vaccination by both genders in Kentucky and on a national scale remains highly underutilized. As a result, preventable incidence and mortality rates from HPV-related illness are elevated. Health care delivery factors such as increased vaccination and preventative care, insurance coverage, and accessible rural health care are necessary for HPV prevention and promotion of holistic health. The ...
Fracture Liaison Services Improve Outcomes Of Patients With Osteoporosis-Related Fractures: A Systematic Literature Review And Meta-Analysis,
2018
National Cheng Kung University
Fracture Liaison Services Improve Outcomes Of Patients With Osteoporosis-Related Fractures: A Systematic Literature Review And Meta-Analysis, Chih-Hsing Wu, Shih-Te Tu, Yin-Fan Chang, Ding-Cheng Chan, Jui-Teng Chien, Chih-Hsueh Lin, Sonal Singh, Manikanta Dasari, Jung-Fu Chen, Keh-Sung Tsai
Open Access Articles
OBJECTIVES: This systematic review and meta-analysis evaluated the outcomes of patients with osteoporosis-related fractures managed through fracture liaison services (FLS) programs.
METHODS: Medline, PubMed, EMBASE, and the Cochrane Library were searched (January 2000-February 2017 inclusive) using the keywords 'osteoporosis', 'fractures', 'liaison', and 'service' to identify randomised controlled trials and observational studies of patients aged > /=50years with osteoporosis-related fractures in hospital, clinic, community, or home-based settings who were managed using FLS. Risk of bias was assessed at outcome level. Meta-analysis followed a random-effects and fixed-effects model. Outcomes of interest were incidence of bone mineral density (BMD) testing, treatment initiation, adherence, re-fractures ...
Ephrinb3 Modulates Hippocampal Neurogenesis And The Reelin Signaling Pathway In A Pilocarpineinduced Model Of Epilepsy,
2018
Central South University
Ephrinb3 Modulates Hippocampal Neurogenesis And The Reelin Signaling Pathway In A Pilocarpineinduced Model Of Epilepsy, Tian-Tian Liu, Yi Li, Yi Shu, Bo Xiao, Li Feng
Open Access Articles
EphrinB3 is important in the regulation of cell proliferation, differentiation and migration via cellcell contact, and can activate the reelin pathway during brain development. However, the effect of ephrinB3 on hippocampal neurogenesis and the reelin pathway in epilepsy remains to be fully elucidated. In the present study, the expression of ephrinB3 in pilocarpineinduced status epilepticus (SE) rats was investigated. SYBR Greenbased reverse transcriptionquantitative polymerase chain reaction analysis, immunohistochemical labeling and western blot analysis were used to detect the gene and protein expression levels of ephrinB3 and reelin pathway proteins. Immunofluorescence staining of doublecortin (DCX) was utilized to analyze hippocampal neurogenesis ...
Avoiding Death Like The Plague: Wound Care In The Roman Army,
2018
Nazareth College of Rochester
Avoiding Death Like The Plague: Wound Care In The Roman Army, Gwendolyn E. Dougherty
#History: A Journal of Student Research
At its peak, Roman Empire controlled over two million square miles of territory. To conquer and control that much land, Rome produced a highly skilled army. Casualties and deaths were to be expected, but ancient medical sources about caring for the wounded in the Roman army point to treatments considered advanced for the time period. Galen of Pergamum was an important contributor to this field. The use of food products and natural resources helped combat infections, healing the wounded soldiers and returning them to their military units. This paper identifies and analyzes what those specific products for wound care were ...
Modeling Hcv Interactions With P53: Implications For Carcinogenesis,
2018
Florida State University
Modeling Hcv Interactions With P53: Implications For Carcinogenesis, Harsh Jain
Biology and Medicine Through Mathematics Conference
No abstract provided.
Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing.,
2018
Virginia Commonwealth University
Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing., J Alex Ratti, Angela Reynolds, Rebecca L. Heise
Biology and Medicine Through Mathematics Conference
No abstract provided.
Study Of Early After Depolarization In A Complex Human Cardiac Cell Model In Tissue,
2018
Georgia Institute of Technology
Study Of Early After Depolarization In A Complex Human Cardiac Cell Model In Tissue, Abouzar Kaboudian, Yanyan Claire Ji, Elizabeth M. Cherry, Flavio H. Fenton
Biology and Medicine Through Mathematics Conference
No abstract provided.
Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys,
2018
Oklahoma State University - Main Campus
Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong
Biology and Medicine Through Mathematics Conference
No abstract provided.
Cognitive Impairment, Vulnerability, And Mortality Post Ischemic Stroke: A Five-Year Follow-Up Of The Action On Secondary Prevention Interventions And Rehabilitation In Stroke (Aspire-S) Cohort,
2018
Royal College of Surgeons in Ireland
Cognitive Impairment, Vulnerability, And Mortality Post Ischemic Stroke: A Five-Year Follow-Up Of The Action On Secondary Prevention Interventions And Rehabilitation In Stroke (Aspire-S) Cohort, Eva Gaynor, Daniela Rohde, Margaret Large, Lisa Mellon, Patricia Hall, Linda Brewer, Orla Conway, Anne Hickey, Kathleen Bennett, Eamon Dolan, Elizabeth Callaly, David Williams
Psychology Articles
Background
The aim of this study was to examine predictors of mortality in patients 5 years after ischemic stroke, focusing on cognitive impairment, vulnerability, and vascular risk factors assessed at 6 months post stroke.
Materials and Methods
Patients from the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) cohort were followed up 5 years post ischemic stroke. Vascular risk factors, cognitive impairment, and vulnerability were assessed at 6 months post stroke. Cognitive impairment was assessed using a cutoff score lower than 26 on the Montreal Cognitive Assessment (MoCA). Vulnerability was defined as a score of 3 or higher ...
2'-5'-Oligoadenylate Synthetase 1 (Oas1) And Health Disparities In Prostate Cancer,
2018
Clark Atlanta University
2'-5'-Oligoadenylate Synthetase 1 (Oas1) And Health Disparities In Prostate Cancer, Aisha S. Hunt
Electronic Theses & Dissertations Collection for Atlanta University & Clark Atlanta University
2’ -5’ –oligoadenylate synthetase 1 (OAS1) is an antiviral enzyme that in the presence of double-stranded RNA structures, such as viral genomes or single-stranded RNA transcripts with significant double-stranded character, converts ATP to a series of 2’ -5’ –oligoadenylates (2-5A). 2-5A promotes dimerization of latent ribonuclease (RNaseL) to form catalytically active RNaseL, a candidate hereditary prostate cancer (PCa) gene. RNaseL is anti-proliferative and promotes senescence and apoptosis in PCa cells. Genotyping analysis was completed on over 600 genomic DNA samples from African-American and Caucasian, normal and PCa subjects. Genotyping was performed to screen the following SNPs in the last exon ...
Regulation Of The Pi3-Kinase/Pten Signaling Pathway By Tgf-Β In Prostate Cancer Cells,
2018
Atlanta University Center
Regulation Of The Pi3-Kinase/Pten Signaling Pathway By Tgf-Β In Prostate Cancer Cells, Mawiyah Kimbrough-Allah
Electronic Theses & Dissertations Collection for Atlanta University & Clark Atlanta University
Transforming growth factor -β (TGF-β) plays an important role in the progression of prostate cancer. It acts as a tumor suppressor in normal epithelial cells but as a tumor promoter in advanced prostate cancer cells. The PI3-kinase pathway has been shown to play integral roles in many cellular processes including cell proliferation, survival, and cell migration in many cell types. PI3-kinase pathway mediates TGF-β effects on prostate cancer cell migration and invasion. Phosphatase and tensin homolog (PTEN), a tumor suppressor gene, inhibits PI3-kinase pathway and is frequently mutated in prostate cancers. In this present study, we investigated possible roles of ...
Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos,
2018
Fordham University
Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender
Student Theses 2015-Present
This paper aims to shed light on the dissonance caused by the superimposition of Dominant Human Systems on Natural Systems. I highlight the synthetic nature of Dominant Human Systems as egoic and linguistic phenomenon manufactured by a mere portion of the human population, which renders them inherently oppressive unto peoples and landscapes whose wisdom were barred from the design process. In pursuing a radical pragmatic approach to mending the simultaneous oppression and destruction of the human being and the earth, I highlight the necessity of minimizing entropic chaos caused by excess energy expenditure, an essential feature of systems that aim ...
South Africa, Hiv/Aids, And Education,
2018
The University of San Francisco
South Africa, Hiv/Aids, And Education, Katie Roberts
Master's Projects and Capstones
Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) are huge problems in South Africa. HIV is a disease that attacks a person’s immune system and, if not properly treated, can lead to AIDS. While there is a treatment—antiretroviral drugs—HIV remains a highly stigmatized disease. This field project focuses on reducing stigma so people are unafraid to get tested or seek treatment. Created to benefit both teachers and their learners, the goal of this mathematics curriculum (consisting of 12 lesson plans and worksheets) is to begin HIV/AIDS awareness in school so accurate information is learned and ...
