Bacterial Infections and Mycoses Commons

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Recent Articles in Bacterial Infections and Mycoses

Mycobacterium Bovis (Bovine Tuberculosis) Infection In North American Wildlife: Current Status And Opportunities For Mitigation Of Risks Of Further Infection In Wildlife Populations, Ryan S. Miller, Steven J. Sweeney University of Nebraska - Lincoln

Mycobacterium Bovis (Bovine Tuberculosis) Infection In North American Wildlife: Current Status And Opportunities For Mitigation Of Risks Of Further Infection In Wildlife Populations, Ryan S. Miller, Steven J. Sweeney

Other Publications in Zoonotics and Wildlife Disease

Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis, has been identified in nine geographically distinct wildlife populations in North America and Hawaii and is endemic in at least three populations, including members of the Bovidae, Cervidae, and Suidae families. The emergence of M. bovis in North American wildlife poses a serious and growing risk for livestock and human health and for the recreational hunting industry. Experience in many countries, including the USA and Canada, has shown that while M. bovis can be controlled when restricted to livestock species, it is almost impossible to eradicate once it has spread ...


Annotation Of Genes Responsible For Synthesis Of Uroporphyrinogen Iii From L-Glutamate, The First Half Of Of The Pathway Of Heme Biosynthetic Pathway, In Kytococcus Sedentarius., Vignesh M. Iyer The College at Brockport: State University of New York

Annotation Of Genes Responsible For Synthesis Of Uroporphyrinogen Iii From L-Glutamate, The First Half Of Of The Pathway Of Heme Biosynthetic Pathway, In Kytococcus Sedentarius., Vignesh M. Iyer

Master's Level Graduate Research Conference

Genome annotation is a set of algorithmic software tools that allows complete sequencing of an organism’s genome. Kytococcus sedentarius is a gram positive bacterium, with callus degrading activity, closely associated with pitted keratolysis. The objective of this study was to annotate the genes in Kytococcus sedentarius strain 541 (DSM 20547) responsible for heme biosynthesis, involving the formation of uroporphyrinogen III from L-Glutamate. Metabolic functions of individual genes were characterized using the Integrated Microbial Genome Annotation Collaboration Toolkit (IMG-ACT) developed by the Joint Genome Institute (University of California, CA). Sequence based similarity was identified using BLAST and T-COFFEE. Cellular localization ...


Involvement Of Interleukin-33/St2 In Myocardial Dysfunction In Murine Model Of Sepsis, Yoonmi Choe Western University

Involvement Of Interleukin-33/St2 In Myocardial Dysfunction In Murine Model Of Sepsis, Yoonmi Choe

Electronic Thesis and Dissertation Repository

The disruption of myocardial extracellular matrix (ECM) has been implicated in myocardial dysfunction during sepsis. However, the underlying mechanism(s) are not clear. Interleukin-33 (IL-33) is a cytokine which regulates collagen synthesis in various cardiac pathologies. The purpose of the present study is to test whether IL-33 contributes to sepsis-induced myocardial dysfunction through regulation of matrix metalloproteinase-9 (MMP-9). The in vivo, feces-induced peritonitis (FIP) in mice and in vitro lipopolysaccharide (LPS) treatments to isolated cardiomyocytes were used. In FIP mice, myocardial IL-33 and MMP-9 expression were increased and myocardial contractility was decreased. Myocardial function in FIP mice was improved when ...


A Novel Murine Infection Model For Shiga Toxin-Producing Escherichia Coli, Emily M. Mallick, Megan E. McBee, Vijay K. Vanguri, Angela R. Melton-Celsa, Katherine Schlieper, Brad J. Karalius, Alison D. O’Brien, Joan R. Butterton, John M. Leong, David B. Schauer University of Massachusetts Medical School

A Novel Murine Infection Model For Shiga Toxin-Producing Escherichia Coli, Emily M. Mallick, Megan E. Mcbee, Vijay K. Vanguri, Angela R. Melton-Celsa, Katherine Schlieper, Brad J. Karalius, Alison D. O’Brien, Joan R. Butterton, John M. Leong, David B. Schauer

GSBS Student Publications

Enterohemorrhagic E. coli (EHEC) is an important subset of Shiga toxin-producing (Stx-producing) E. coli (STEC), pathogens that have been implicated in outbreaks of food-borne illness and can cause intestinal and systemic disease, including severe renal damage. Upon attachment to intestinal epithelium, EHEC generates "attaching and effacing" (AE) lesions characterized by intimate attachment and actin rearrangement upon host cell binding. Stx produced in the gut transverses the intestinal epithelium, causing vascular damage that leads to systemic disease. Models of EHEC infection in conventional mice do not manifest key features of disease, such as AE lesions, intestinal damage, and systemic illness. In ...


Prevalence And Antimicrobial Agent Susceptibility Of Methicillin-Resistant Staphylococcus Aureus In Healthy Pediatric Outpatients In Las Vegas, Echezona E. Ezeanolue, Mark P. Buttner, Patricia Cruz, Joanne L. Henry, Chad L. Cross, Linda D. Stetzenbach University of Nevada, Las Vegas

Prevalence And Antimicrobial Agent Susceptibility Of Methicillin-Resistant Staphylococcus Aureus In Healthy Pediatric Outpatients In Las Vegas, Echezona E. Ezeanolue, Mark P. Buttner, Patricia Cruz, Joanne L. Henry, Chad L. Cross, Linda D. Stetzenbach

Nevada Journal of Public Health

Colonization and infection by community-associated resistant strains of Staphylococcus aureus are being reported in epidemic proportions. The purpose of this study was to determine the local prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in children and to characterize the MRSA isolates in the laboratory with regard to antimicrobial agent susceptibility patterns, and the presence of the mecA and the Panton-Valentine leukocidin (PVL) genes. Nasal swabs were collected at two pediatric clinics from a total of 505 children during health maintenance visits. A brief questionnaire was administered to collect demographic data and pertinent medical, family, and social history. Samples were cultured ...


A Mixed Methods Approach To Food Safety Knowledge, Beliefs And Practices In Hispanic Families With Young Children In Nebraska, Kristen M. Stenger University of Nebraska - Lincoln

A Mixed Methods Approach To Food Safety Knowledge, Beliefs And Practices In Hispanic Families With Young Children In Nebraska, Kristen M. Stenger

Open Access Theses and Dissertations from the College of Education and Human Sciences

This mixed methods study addresses food safety for Hispanic families with young children in Nebraska. A convergent mixed methods design was used, where qualitative and quantitative data were collected in parallel, analyzed separately and then merged in analysis and interpretation. A quantitative food safety knowledge survey (n=90, 52 from focus groups, 38 from piloting the survey), was used to assess the FightBac!™ concepts: Clean, Separate, Cook, Chill, and two additional concepts: foods that increase risk, and groups at increased risk. Qualitative focus groups explored food safety handling beliefs and practices through the lens of the Health Belief Model. Focus ...