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Parts Of The Whole: Teaching Quantitative Reasoning In The Predator-Prey Model, Dorothy Wallace 2016 Dartmouth College

Parts Of The Whole: Teaching Quantitative Reasoning In The Predator-Prey Model, Dorothy Wallace

Numeracy

The classical predator-prey equations are in nearly every differential equations text and mathematical biology text. Usually they are presented fait accompli, leaving the student to analyze them or play with a computer program. Here we show that the process of fully understanding where these equations come from and how they are derived provides numerous opportunities to teach or reinforce quantitative reasoning skills necessary to future scientists. This example is used to invoke logic, systems thinking, causal reasoning, understanding functions of one or more variables, quantities versus rates of change, proportional reasoning, unit analysis, and comparison to data.


Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird 2015 Wright State University - Main Campus

Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird

Biological Sciences Faculty Publications

Haldane's Rule and Darwin's Corollary to Haldane's Rule are the observations that heterogametic F1 hybrids frequently are less fit than their homogametic siblings and that asymmetric results often are obtained from reciprocal hybrid crosses. In Caenorhabditis, Haldane's Rule and Darwin's Corollary have been observed in several hybrid crosses, including crosses of Caenorhabditis briggsae and Caenorhabditis nigoni. Fertile F1 females are obtained from reciprocal crosses. However, F1 males obtained from C. nigoni mothers are sterile and F1 males obtained from C. briggsae die during embryogenesis. We have identified cbr-him-8 as a recessive maternal-effect suppressor of F1 ...


The Conformation Of Yeast Chromosome Iii Is Mating Type Dependent And Controlled By The Recombination Enhancer, Jon-Matthew Belton, Bryan R. Lajoie, Sylvain Audibert, Sylvain Cantaloube, Imen Lassadi, Isabelle Goiffon, Davide Bau, Marc A. Marti-Renom, Kerstin Bystricky, Job Dekker 2015 University of Massachusetts Medical School

The Conformation Of Yeast Chromosome Iii Is Mating Type Dependent And Controlled By The Recombination Enhancer, Jon-Matthew Belton, Bryan R. Lajoie, Sylvain Audibert, Sylvain Cantaloube, Imen Lassadi, Isabelle Goiffon, Davide Bau, Marc A. Marti-Renom, Kerstin Bystricky, Job Dekker

Open Access Articles

Mating-type switching in yeast occurs through gene conversion between the MAT locus and one of two silent loci (HML or HMR) on opposite ends of the chromosome. MATa cells choose HML as template, whereas MATalpha cells use HMR. The recombination enhancer (RE) located on the left arm regulates this process. One long-standing hypothesis is that switching is guided by mating-type-specific and possibly RE-dependent chromosome folding. Here, we use Hi-C, 5C, and live-cell imaging to characterize the conformation of chromosome III in both mating types. We discovered a mating-type-specific conformational difference in the left arm. Deletion of a 1-kb subregion within ...


Hic-Pro: An Optimized And Flexible Pipeline For Hi-C Data Processing, Nicolas Servant, Nelle Varoquaux, Bryan R. Lajoie, Eric Viara, Chong-Jian Chen, Jean-Philippe Vert, Edith Heard, Job Dekker, Emmanuel Barillot 2015 Institut Curie

Hic-Pro: An Optimized And Flexible Pipeline For Hi-C Data Processing, Nicolas Servant, Nelle Varoquaux, Bryan R. Lajoie, Eric Viara, Chong-Jian Chen, Jean-Philippe Vert, Edith Heard, Job Dekker, Emmanuel Barillot

Open Access Articles

HiC-Pro is an optimized and flexible pipeline for processing Hi-C data from raw reads to normalized contact maps. HiC-Pro maps reads, detects valid ligation products, performs quality controls and generates intra- and inter-chromosomal contact maps. It includes a fast implementation of the iterative correction method and is based on a memory-efficient data format for Hi-C contact maps. In addition, HiC-Pro can use phased genotype data to build allele-specific contact maps. We applied HiC-Pro to different Hi-C datasets, demonstrating its ability to easily process large data in a reasonable time. Source code and documentation are available at http://github.com/nservant ...


Transgenic Insecticidal Corn: The Agronomic And Ecological Rationale For Its Use, Eldon Ortman, B. Dean Barry, Lawrent Buschman, Dennis Calvin, Janet Carpenter, Galen Dively, John Foster, Billy Fuller, Richard Hellmich, Randall Higgins, Thomas Hunt, Gary Munkvold, Kenneth Ostlie, Marlin Rice, Richard Roush, Mark Sears, Anthony Shelton, Blair Siegfried, Phillip Sloderbeck, Kevin Steffey, F. Tom Turpin, John Wedberg 2015 Purdue University

Transgenic Insecticidal Corn: The Agronomic And Ecological Rationale For Its Use, Eldon Ortman, B. Dean Barry, Lawrent Buschman, Dennis Calvin, Janet Carpenter, Galen Dively, John Foster, Billy Fuller, Richard Hellmich, Randall Higgins, Thomas Hunt, Gary Munkvold, Kenneth Ostlie, Marlin Rice, Richard Roush, Mark Sears, Anthony Shelton, Blair Siegfried, Phillip Sloderbeck, Kevin Steffey, F. Tom Turpin, John Wedberg

Gary P. Munkvold

The scientific community has examined the risks and benefits of Bt plants more than any other novel agricultural technology developed over the past two decades, as demonstrated by the vast body of literature, scientific discussions, and numerous public meetings facilitated by the EPA, the US Department of Agriculture, and the US Food and Drug Administration on this subject.We find the evidence to date supports the appropriate use of Bt corn as one component in the economically and ecologically sound management of lepidopteran corn pests.


Cold-Acclimation Reduces Co2 Sensitivity Of Chemosensory Locus Coeruleus Neurons Of American Bullfrogs, Lithobates Catesbeianus, Joseph Santin, Lynn Hartzler 2015 Wright State University - Main Campus

Cold-Acclimation Reduces Co2 Sensitivity Of Chemosensory Locus Coeruleus Neurons Of American Bullfrogs, Lithobates Catesbeianus, Joseph Santin, Lynn Hartzler

Lynn K. Hartzler

No abstract provided.


Mcnamara 201412 Nih Scap Innocentive Challenge Solution - T-Bow Rainbow T-Cells And Tumor Cells Spatial Multiplexing Gene Expression Reporter System – Plus Supplement Plus Posters - 20151027 - Please Download "75" Instead, George McNamara 2015 M.D. Anderson Cancer Center

Mcnamara 201412 Nih Scap Innocentive Challenge Solution - T-Bow Rainbow T-Cells And Tumor Cells Spatial Multiplexing Gene Expression Reporter System – Plus Supplement Plus Posters - 20151027 - Please Download "75" Instead, George Mcnamara

George McNamara

McNamara 201412 NIH SCAP InnoCentive Challenge Solution - T-Bow Rainbow T-cells and Tumor Cells Spatial Multiplexing Gene Expression Reporter System – plus supplement plus posters - 20151027.

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Please download the current 20151027 (October 27, 2015) Tattletales and T-Bow update from

http://works.bepress.com/gmcnamara/75/

The bepress web site is not letting me replace the old pdf here at "65" with the additional 10 pages update.

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The download is my/Cooper lab solution (submission) to the 2014 NIH Single Cell Analysis Program (SCAP) InnoCentive Challenge, "Follow That Cell". I submitted the Solution on 20141215Mon (with 20 minutes to spare). The Challenge web ...


Chromatin Interaction Analysis Reveals Changes In Small Chromosome And Telomere Clustering Between Epithelial And Breast Cancer Cells, Ahmet Rasim Barutcu, Bryan R. Lajoie, Rachel Patton McCord, Coralee E. Tye, Deli Hong, Terri L. Messier, Gillian Browne, Andre J. van Wijnen, Jane B. Lian, Janet L. Stein, Job Dekker, Anthony N. Imbalzano, Gary S. Stein 2015 University of Massachusetts Medical School

Chromatin Interaction Analysis Reveals Changes In Small Chromosome And Telomere Clustering Between Epithelial And Breast Cancer Cells, Ahmet Rasim Barutcu, Bryan R. Lajoie, Rachel Patton Mccord, Coralee E. Tye, Deli Hong, Terri L. Messier, Gillian Browne, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, Job Dekker, Anthony N. Imbalzano, Gary S. Stein

Program in Systems Biology Publications and Presentations

BACKGROUND: Higher-order chromatin structure is often perturbed in cancer and other pathological states. Although several genetic and epigenetic differences have been charted between normal and breast cancer tissues, changes in higher-order chromatin organization during tumorigenesis have not been fully explored. To probe the differences in higher-order chromatin structure between mammary epithelial and breast cancer cells, we performed Hi-C analysis on MCF-10A mammary epithelial and MCF-7 breast cancer cell lines.

RESULTS: Our studies reveal that the small, gene-rich chromosomes chr16 through chr22 in the MCF-7 breast cancer genome display decreased interaction frequency with each other compared to the inter-chromosomal interaction frequency ...


'In' Or 'As' Space?: A Model Of Complexity, With Philosophical, Simulatory, And Empirical Ramifications, Charles Smith 2015 Western Kentucky University

'In' Or 'As' Space?: A Model Of Complexity, With Philosophical, Simulatory, And Empirical Ramifications, Charles Smith

Charles H. Smith

A General Systems model based on ideas originating with the writings of Benedict de Spinoza is described, starting with its philosophical underpinnings, and proceeding on to its relation to modern systems concepts, including attempts to simulate the relationships posed, and measure real world structures. Central to the idea is the notion that spatial extension may not have a prior existence, but emerges only through an entropy maximization process in which information and energy exchange is balanced among some limited number of subsystems that in sum comprise any given functioning complex system. Related published empiricism concerning geographical/geological systems – the hypsometry ...


Context Management Toolbox: A Linear Sequential Unmasking (Lsu) Approach For Minimizing Cognitive Bias In Forensic Decision Making, Itiel Dror, William Thompson, Christian Meissner, Irving Kornfield, Dan Krane, Michael Saks, Michael Risinger 2015 Wright State University - Main Campus

Context Management Toolbox: A Linear Sequential Unmasking (Lsu) Approach For Minimizing Cognitive Bias In Forensic Decision Making, Itiel Dror, William Thompson, Christian Meissner, Irving Kornfield, Dan Krane, Michael Saks, Michael Risinger

Dan E. Krane

No abstract provided.


Relation Of Riparian Buffer Strips To In-Stream Habitat, Macroinvertebrates And Fish In A Small Iowa Stream, Jeremy Duehr, Michael Siepker, Clay Pierce, Thomas Isenhart 2015 Iowa State University

Relation Of Riparian Buffer Strips To In-Stream Habitat, Macroinvertebrates And Fish In A Small Iowa Stream, Jeremy Duehr, Michael Siepker, Clay Pierce, Thomas Isenhart

Thomas M. Isenhart

Macroinvertebrate and fish habitat is often degraded as a result of agriculture. Riparian buffer strips are commonly used to counteract the negative effects of agriculture in headwater streams. We assessed the relation of multi-aged riparian buffer strips to in-stream habitat, macroinvertebrate and fish assemblages in an Iowa stream. In-stream habitat, macroinvertebrates, and fish were sampled from two buffered sites and two unbuffered sites, with the greatest substrate, water depth, and velocity heterogeneity occurring in buffered sites. The highest macroinvertebrate richness (11) as well as fish species richness (14), diversity (1.99) and IBI score (37) were found in the site ...


Measuring Teaching Best Practice In The Induction Years: Development And Validation Of An Item-Level Assessment, Laura Kingsley, William Romine 2015 Wright State University - Main Campus

Measuring Teaching Best Practice In The Induction Years: Development And Validation Of An Item-Level Assessment, Laura Kingsley, William Romine

William L. Romine

Schools and teacher induction programs around the world routinely assess teaching best practice to inform accreditation, tenure/promotion, and professional development decisions. Routine assessment is also necessary to ensure that teachers entering the profession get the assistance they need to develop and succeed. We introduce the Item-Level Assessment of Teaching practice (I-LAST) as a flexible framework-based approach for quantitative evaluation of teaching best practice in the induction stages. We based the I-LAST on a novel framework for teaching best practice, and used Fuller’s scale as a framework for understanding the potential of the I-LAST in providing longitudinal measures for ...


Development And Evaluation Of A Model For Secondary Evolution Educators’ Professional Development Needs, William Romine, Ellen Barnett, Patricia Friedrichsen, Aaron Sickel 2015 Wright State University - Main Campus

Development And Evaluation Of A Model For Secondary Evolution Educators’ Professional Development Needs, William Romine, Ellen Barnett, Patricia Friedrichsen, Aaron Sickel

William L. Romine

Background

Professional development (PD) efforts have improved acceptance and pedagogical practice related to the theory of evolution in high school biology teachers. However, these teachers express need for more PD related to evolution. It therefore becomes necessary to understand teachers’ PD needs prior to structuring PD efforts.

Methods

We formulated and validated a model to explain secondary teachers’ PD needs using data from a survey of 276 secondary biology teachers who reported teaching evolution.

Results

In addition to reliable subscales, we found that obstacles to teaching evolution, school and community support for evolution instruction, confidence in evolution instruction, and prior ...


Tossing The Coin For Half Life, William Romine 2015 Wright State University - Main Campus

Tossing The Coin For Half Life, William Romine

William L. Romine

No abstract provided.


Customization Of Curriculum Materials In Science: Motives, Challenges, And Opportunities, William Romine, Tanvi Banerjee 2015 Wright State University - Main Campus

Customization Of Curriculum Materials In Science: Motives, Challenges, And Opportunities, William Romine, Tanvi Banerjee

William L. Romine

Exemplary science instructors use inquiry to tailor content to student’s learning needs; traditional textbooks treat science as a set of facts and a rigid curriculum. Publishers now allow instructors to compile pieces of published and/or self-authored text to make custom textbooks. This brings numerous advantages, including the ability to produce smaller, cheaper text and added flexibility on the teaching models used. Moreover, the internet allows instructors to decentralize textbooks through easy access to educational objects such as audiovisual simulations, individual textbook chapters, and scholarly research articles. However, these new opportunities bring with them new problems. With educational materials ...


Expectations To Success—The Contrasting Journeys Of A Teacher And His Coach, William Romine, Andrew West, Mark Volkmann 2015 Wright State University - Main Campus

Expectations To Success—The Contrasting Journeys Of A Teacher And His Coach, William Romine, Andrew West, Mark Volkmann

William L. Romine

No abstract provided.


Practical Assessment Of The Ngss And Ohio Standards In Time-Constrained Classroom Settings, William Romine, Amber Todd 2015 Wright State University - Main Campus

Practical Assessment Of The Ngss And Ohio Standards In Time-Constrained Classroom Settings, William Romine, Amber Todd

William L. Romine

No abstract provided.


Impacts Of Gaming, Teachers, And Interest On Student Science Learning Associated With Innovative Biotechnology Curricula, Troy Sadler, William Romine, Deepika Menon, Michelle Klosterman, Leonard Annetta 2015 Wright State University - Main Campus

Impacts Of Gaming, Teachers, And Interest On Student Science Learning Associated With Innovative Biotechnology Curricula, Troy Sadler, William Romine, Deepika Menon, Michelle Klosterman, Leonard Annetta

William L. Romine

No abstract provided.


How Does A Siamese Cat Get Its Color?, William Romine, Amber Todd 2015 Wright State University - Main Campus

How Does A Siamese Cat Get Its Color?, William Romine, Amber Todd

William L. Romine

No abstract provided.


Configurational Entropy Modeling Of The Viscosity Of Hydrous Albitic, Granitic And Rhyolitic Melts, Alan Whittington, A. Bouhifd, Anne Hofmeister, P. Richet, William Romine 2015 Wright State University - Main Campus

Configurational Entropy Modeling Of The Viscosity Of Hydrous Albitic, Granitic And Rhyolitic Melts, Alan Whittington, A. Bouhifd, Anne Hofmeister, P. Richet, William Romine

William L. Romine

No abstract provided.


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