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Attenuation Of Mtorc1-Driven Secretion Of Lipoproteins And Triacylglycerides By Short Chain Fatty Acids: Mechanistic Insight Into The Pathogenesis Of Hypertriglyceridemia, Joseph L. Roberts 2015 University of Nebraska-Lincoln

Attenuation Of Mtorc1-Driven Secretion Of Lipoproteins And Triacylglycerides By Short Chain Fatty Acids: Mechanistic Insight Into The Pathogenesis Of Hypertriglyceridemia, Joseph L. Roberts

Nutrition & Health Sciences Dissertations & Theses

The mechanistic target of rapamycin complex 1 (mTORC1) is a serine/threonine kinase that drives several anabolic processes including lipid synthesis, protein synthesis, and adipogenesis. mTORC1 is highly active in the livers of obese rodents, in overnutrition, and is implicated in the development of obesity related metabolic disorders, including the overproduction of atherogenic lipoproteins. Direct inhibition of mTORC1 is not a viable treatment strategy because it prevents feedback inhibition of the insulin-signaling cascade, leading to increased lipid synthesis and secretion of lipoproteins. Thus, therapeutic approaches that drive catabolic pathways are considered promising mechanisms for overcoming mTORC1-driven anabolism. Human liver HepG2 ...


Decolonizing The Diet: Synthesizing Native-American History, Immunology, And Nutritional Science., Gideon Mailer, Nicola Hale 2015 University of Minnesota - Duluth

Decolonizing The Diet: Synthesizing Native-American History, Immunology, And Nutritional Science., Gideon Mailer, Nicola Hale

Journal of Evolution and Health

This article examines historical evidence that correlates a decline in Native American health and fertility with ruptures to indigenous food systems following European colonization. It suggests new interdisciplinary ways to study the association between breached indigenous nutritional practices and a decline in Native American health. These objectives bring together students of history and natural science and entail new ways of synthesizing hitherto separate scholarly enterprises in the classroom. In light of the most cutting-edge scientific literature on nutrition, metabolic syndrome, and immunology, they require a new consideration of the historical association between Native American health and indigenous food systems.


Woodrow Wilson’S Ideological War: American Intervention In Russia, 1918-1920, Shane Hapner 2015 Wright State University

Woodrow Wilson’S Ideological War: American Intervention In Russia, 1918-1920, Shane Hapner

Best Integrated Writing

Shane Hapner analyzes the effects of Woodrow Wilson’s principle of self-determination on American intervention in Russia from 1918-1920 in this essay written for the Integrated Writing course HST 4220: Soviet Union, taught by Dr. Seam Pollock at Wright State University.


Circular Thinking: An Original Analysis Of Lord Of The Flies, John Callon 2015 Wright State University

Circular Thinking: An Original Analysis Of Lord Of The Flies, John Callon

Best Integrated Writing

John Callon examines traits of circular thinking and imagery in William Golding’s Lord of the Flies in this essay written for the Integrated Writing course ENG 4560: Capstone in Integrated Language Arts Curriculum, taught by Dr. Nancy Mack at Wright State University.


Are The Main Institutional Changes That Created The “Business Man” Still Relevant?, Hayden Joblin 2015 Wright State University

Are The Main Institutional Changes That Created The “Business Man” Still Relevant?, Hayden Joblin

Best Integrated Writing

Hayden Joblin examines the forces driving the evolution of the modern business man and whether those still have relevance in this essay written for the Integrated Writing course EC 3190: Institutional Economics, taught by Dr. Hee Young Shin at Wright State University.


Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten 2015 Wright State University

Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten

Best Integrated Writing

Erin Dorsten makes a proposal for a scientific study of experiments to identify genes involved in protecting an organism with negligible senescence from tumor formation in this piece written for the Integrated Writing course BIO 4020: Current Literature: Biology of Regeneration, taught by Labib Rouhana at Wright State University.


The Barb Report, Elizabeth Schoppelrei 2015 Wright State University

The Barb Report, Elizabeth Schoppelrei

Best Integrated Writing

Elizabeth Schoppelrei explores issues of sexuality, kindness, masculinity, discrimination, and respect in this short story written for the Integrated Writing course ENG 4830: Advanced Fiction Writing Seminar, taught by Dr. Erin Flanagan at Wright State University.


How To Recover From The Great Recession And Reduce The Government Debt, Hunter Cregger 2015 Wright State University

How To Recover From The Great Recession And Reduce The Government Debt, Hunter Cregger

Best Integrated Writing

Hunter Cregger proposes how to recover from the Great Recession of the 2000s and reduce government debt in this essay written for the Integrated Writing course EC 2050: Principles of Macroeconomics, taught by Dr. Hee Young Shin at Wright State University.


Inter-Tribal Disunity: An Analysis Of Inter-Tribal Conflict During The Black Hawk War Of 1832, Megan Bailey 2015 Wright State University

Inter-Tribal Disunity: An Analysis Of Inter-Tribal Conflict During The Black Hawk War Of 1832, Megan Bailey

Best Integrated Writing

Megan Bailey explores the effects of inter-tribal disunity and conflict on the Black Hawk War of 1832 in this essay written for the Integrated Writing course HST 3000: Introduction to Historical Analysis, taught by Dr. Noeleen McIlvenna at Wright State University.


Effects Of Caffeine And Vitamin E On Wisconsin Fast Plant, Sarah Ferguson 2015 Wright State University

Effects Of Caffeine And Vitamin E On Wisconsin Fast Plant, Sarah Ferguson

Best Integrated Writing

Sarah Ferguson examines the effects of caffeine and vitamin E on the growth of Wisconsin Fast Plant in this piece written for the Integrated Writing course BIO 3450: Concepts of Biology I for Early and Middle Childhood Education, taught by Mr. Len Kenyon at Wright State University.


Best Integrated Writing 2015 - Complete Edition, 2015 Wright State University

Best Integrated Writing 2015 - Complete Edition

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.


Gmo Vs. Non-Gmo: Comparing The Addictiveness Of Corn In Rats, Christian A. Carroll, Sara L. Hill, Kelly A. Huston, Tyler Michael, Courtney Noll 2015 Cedarville University

Gmo Vs. Non-Gmo: Comparing The Addictiveness Of Corn In Rats, Christian A. Carroll, Sara L. Hill, Kelly A. Huston, Tyler Michael, Courtney Noll

The Research and Scholarship Symposium

Genetically modified organisms (GMOs) refer to organisms whose DNA has been altered to produce a certain characteristic. GMOs account for a significant proportion of the crops produced in the United States. Specifically, GMO corn accounted for approximately 88% of all corn grown for human and animal consumption in the year 2012. Previously conducted studies have not uniformly demonstrated the safe use of GMO corn, and no studies have been conducted to analyze the addictiveness of GMO corn.

The idea of addiction refers to more than just a physical dependence, but to a psychological dependence on something as well. Addiction is ...


Is Fortification Or Bio Fortification Of Staple Food Crops Will Offer A Simple Solution To Complex Nutritional Disorder In Developing Countries?, Mahalingam Govindaraj 2015 ICRISAT

Is Fortification Or Bio Fortification Of Staple Food Crops Will Offer A Simple Solution To Complex Nutritional Disorder In Developing Countries?, Mahalingam Govindaraj

Mahalingam Govindaraj

Large segment of global populations, especially in developing countries is currently at risk from one or more micronutrient deficiency, so called malnutrition. This could be due to our current food systems are fail to provide enough balanced dietary nutrients to meet all the nutritional requirements of every individual, especially resource-poor women and children in the developing countries. A variety of interventions have been used to address micronutrient malnutrition so far such as pharmaceutical supplementation, industrial fortifications and dietary diversification. However, success of supplementation and fortification in developing countries remains challenges due to poor infrastructure, delivery system, more often it need ...


Micrornas Are Absorbed In Biologically Meaningful Amounts From Nutritionally Relevant Doses Of Cow’S Milk And Chicken Eggs And Affect Gene Expression In Peripheral Blood Mononuclear Cells, Cell Cultures, And Mouse Livers, Scott Baier 2015 University of Nebraska-Lincoln

Micrornas Are Absorbed In Biologically Meaningful Amounts From Nutritionally Relevant Doses Of Cow’S Milk And Chicken Eggs And Affect Gene Expression In Peripheral Blood Mononuclear Cells, Cell Cultures, And Mouse Livers, Scott Baier

Nutrition & Health Sciences Dissertations & Theses

Throughout the twenty-first century, evidence has been continually increasing to show the importance of epigenetic regulation in health. While the term “epigenetics” can be applied to many different processes, the focus of this dissertation will be on microRNAs and chromatin structure. Ultimately, both of these forms of epigenetic regulation can be used to fine tune gene expression based on environmental cues. The first three chapters of the dissertation focus on microRNA bioavailability, stability, and function from two commonly consumed food products: cow’s milk and chicken eggs. This important work has been the first of its kind to demonstrate the ...


Stability And Biological Activity Of Dietary Micrornas, Katherine Howard 2015 University of Nebraska-Lincoln

Stability And Biological Activity Of Dietary Micrornas, Katherine Howard

Nutrition & Health Sciences Dissertations & Theses

MicroRNAs play important roles in gene regulation by binding to complimentary sites at the 3’ untranslated region of target mRNA molecules. Binding results in inhibition or degradation of target mRNA. Many bovine and chicken microRNA are homologous with human counterparts enabling gene regulation. A recent study in our lab provided undisputable evidence that endogenous milk microRNAs are bioavailable in humans; resulting in regulation of human gene expression. Based on these findings, we wanted to explore the possibility that other exogenous food borne microRNAs are able to be absorbed through the diet. My thesis surrounds two aims: 1) assessing the stability ...


Resistance Training Improves Muscular Strength And Lymphedema In Breast Cancer Survivors, Caitlin M. Coviello 2015 Florida State University

Resistance Training Improves Muscular Strength And Lymphedema In Breast Cancer Survivors, Caitlin M. Coviello

Undergraduate Research Symposium 2015

Breast cancer survivors (BCS) encounter side effects from cancer treatments that reduce muscular strength. Studies show resistance training (RT) in BCS can improve strength. One concern with RT in BCS is increasing lymphedema, which is swelling of the arms from lymph node removal and is a common side effect in BCS. Studies suggest low to moderate RT may improve or reduce the risk of developing lymphedema. PURPOSE: To evaluate the efficacy of a moderate to high intensity RT intervention to improve muscular strength and lymphedema in BCS over a 12-week period. METHODS: Thirty-three (age: 59±8yrs; BMI: 27.2±5 ...


Probiotic And Prebiotic Supplementation In Lactose Intolerant Subjects, Haleigh Hemond 2015 Florida State University

Probiotic And Prebiotic Supplementation In Lactose Intolerant Subjects, Haleigh Hemond

Undergraduate Research Symposium 2015

The aims of this study were as follows: o Aim 1: To evaluate the effect of a 5-week probiotic treatment on gastrointestinal symptoms and breath hydrogen exhalation followed by 5 weeks of the same probiotic blend in combination with a prebiotic product in lactose intolerant (LI) subjects. o Aim 2: To determine whether probiotic and prebiotic supplements are feasible to use and acceptable to subjects. o Aim 3: To provide calcium education catered to a lactose intolerant population and measure effectiveness of educational sessions. Twenty female and male LI participants underwent hydrogen breath tests and symptom assessment at baseline, midpoint ...


Ocean Food Systems, Barry A. Costa-Pierce 2015 University of New England

Ocean Food Systems, Barry A. Costa-Pierce

Marine Sciences Faculty Presentations

Presentation given during session on Food Justice, where Barton Seaver, Director of the Healthy and Sustainable Food Program in the T.H. Chan School of Public Health at Harvard, described a great nutrition and health crisis in America perpetuated by groups demarketing seafood and promoting meat in the American diet. Seaver noted that Americans consume about 167 lbs. of meat a year and only 14 lbs. of seafood, leading to connected public health and environmental crises, heart disease, and obesity.

According to presenter Barry Costa-Pierce:

Seafood systems in the USA are our most insane foods; America imports nearly every seafood ...


The Significance Of Whole Grain Teff For Improving Nutrition: From Injera To Ready To Eat Porridge By Using Extrusion Cooking Technology, Helen T. Zewdie, Mammo Muchie 2015 University of Pretoria, South Africa

The Significance Of Whole Grain Teff For Improving Nutrition: From Injera To Ready To Eat Porridge By Using Extrusion Cooking Technology, Helen T. Zewdie, Mammo Muchie

International Journal of African Development

Teff (EragrostisTef) is a fascinating grain, ancient, minute in size, packed with nutrition and used for centuries as the principal ingredient of the Ethiopian population diet. The micro- and macronutrients level of teff grainis apparently higher than that of barley, wheat and sorghum and the amino acid composition comparable to that of egg protein, except for its lower lysine content. In Ethiopia, it has been using as a staple food by making flat bread called Injera. Teff can be diversified from its current provision of Injera to other forms like instant porridge to improve the nutritional quality and it may ...


Effects Of Panelist Participation Frequency And Questionnaire Design On Overall Acceptance Scoring For Food Sensory Evaluation In Consumer Central Location Tests, Mauresa Bastian 2015 Brigham Young University - Provo

Effects Of Panelist Participation Frequency And Questionnaire Design On Overall Acceptance Scoring For Food Sensory Evaluation In Consumer Central Location Tests, Mauresa Bastian

All Theses and Dissertations

Two studies were conducted to determine the effect of panelist participation frequency and specific aspects of questionnaire design on overall acceptance scoring in consumer central location tests. Regarding participation frequency, research subjects who participate frequently in some survey types are known to provide responses that differ from subjects who participate less frequently, known as panel conditioning. With respect to questionnaire design, overall acceptance (OA) question placement and usage of pre-evaluation instructions (PEI) in questionnaires for food sensory analysis may bias consumers' scores via carry-over effects. To investigate these concerns, data from consumer sensory panels previously conducted at a central location ...


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