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The Effect Of Angiotensin Converting Enzyme Genotype On Aerobic Capacity Following High Intensity Interval Training, Nicole Goddard, Matthew Baker, Tim Higgins, Christian Cobbold 2014 Western Kentucky University

The Effect Of Angiotensin Converting Enzyme Genotype On Aerobic Capacity Following High Intensity Interval Training, Nicole Goddard, Matthew Baker, Tim Higgins, Christian Cobbold

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 250-259, 2014. Obesity increases the risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Physical activity can reduce T2DM and CVD risk, and increase aerobic capacity, a significant predictor of all-cause mortality and morbidity. High intensity interval training (HIIT) produces similar improvements in aerobic capacity to continuous moderate exercise (CME). Different genotypes of angiotensin converting enzyme (ACE) have been implicated in improving aerobic capacity and therefore predicted health. This study investigated the effects of different ACE genotypes on the impact of 6 weeks of HIIT on aerobic capacity, and thus ...


Contributions Of After School Programs To The Development Of Fundamental Movement Skills In Children, E Jean Burrows, Melanie R. Keats, Angela M. Kolen 2014 Western Kentucky University

Contributions Of After School Programs To The Development Of Fundamental Movement Skills In Children, E Jean Burrows, Melanie R. Keats, Angela M. Kolen

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 236-249, 2014. Fundamental movement skill (FMS) proficiency or the ability to perform basic skills (e.g., throwing, catching and jumping) has been linked to participation in lifelong physical activity. FMS proficiency amongst children has declined in the previous 15 years, with more children performing FMS at a low-mastery level. These declines may help explain the insufficient levels of participation in health promoting physical activity seen in today’s youth. The after school time period (e.g., 3 to 6 p.m.), is increasingly considered an opportune time for physical activity interventions. To date ...


The Energy Expenditure Of Recreational Ballroom Dance, D. E. Lankford, T. W. Bennion, J. King, N. Hessing, L Lee, D. P. Heil 2014 Western Kentucky University

The Energy Expenditure Of Recreational Ballroom Dance, D. E. Lankford, T. W. Bennion, J. King, N. Hessing, L Lee, D. P. Heil

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 228-235, 2014. The popularity of recreational ballroom dancing has increased dramatically in recent years. Yet, relatively little information is known regarding the physiological demands of ballroom dancing. The purpose of this study was to determine the energy requirements for recreational ballroom dancing. 24 participants volunteered including 12 women (mean ± SD: 21 ± 3 yrs, 165.8 ± 7.4 cm, 56.8 ± 11.1 kg) and 12 men (23 ± 1 yr, 175.5 ± 8.4 cm, 78.1 ± 15.6 kg). Gas exchange was recorded using a portable metabolic system during a series of five ...


The Influence Of Exercise Environment And Gender On Mood And Exertion, Thomas G. Plante PhD, ABPP, Marily A. Opezzo PhD, L. Aislinn Diaz, Selena Pistoresi, Michael Santos, Jacqueline E. Fahey, Elizabeth Kay, Briana Britton, Suheel Khan 2014 Western Kentucky University

The Influence Of Exercise Environment And Gender On Mood And Exertion, Thomas G. Plante Phd, Abpp, Marily A. Opezzo Phd, L. Aislinn Diaz, Selena Pistoresi, Michael Santos, Jacqueline E. Fahey, Elizabeth Kay, Briana Britton, Suheel Khan

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 220-227, 2014. This study examined the influence of exercise environment and gender on post-exercise mood and exertion. College student participants (55 females, 49 males) were instructed to pedal a stationary bike at a moderate pace for 20 minutes. Participants were randomly assigned to one of three laboratory conditions: (1) exercising in front of a mirror and posters showing ideal fit body types (i.e., celebrity male and female personal trainers), (2) exercising in front of a mirror only, or (3) a control condition in which participants exercised without a mirror or posters. The ...


Acute Post-Activation Potentiation In Ncaa Division Ii Female Athletes, Kaiya Senn Sygulla, Charles J. Fountaine 2014 Western Kentucky University

Acute Post-Activation Potentiation In Ncaa Division Ii Female Athletes, Kaiya Senn Sygulla, Charles J. Fountaine

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 212-219, 2014. Post-activation potentiation (PAP) is a phenomenon in which the power output of a muscle is immediately enhanced after heavy resistance exercise. Whereas the majority of PAP research has examined males, minimal research exists as to how female athletes respond. Therefore, the purpose of this study was to investigate the acute PAP response of back squats on static squat jump (SSJ) performance among NCAA Division II female athletes. Female athletes (n=29) who were current roster members from basketball, softball, and volleyball, performed 3 SSJ prior to 3 repetitions of the back ...


An Acute Bout Of Self-Myofascial Release In The Form Of Foam Rolling Improves Performance Testing, Corey A. Peacock, Darren D. Krein, Tobin A. Silver, Gabriel J. Sanders, Kyle-Patrick A. von Carlowitz 2014 Western Kentucky University

An Acute Bout Of Self-Myofascial Release In The Form Of Foam Rolling Improves Performance Testing, Corey A. Peacock, Darren D. Krein, Tobin A. Silver, Gabriel J. Sanders, Kyle-Patrick A. Von Carlowitz

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 202-211, 2014. Recent developments in the strength and conditioning field have shown the incorporation of foam rolling self-myofascial release in adjunct with a dynamic warm-up. This is thought to improve overall training performance; however, minimal research exists supporting this theory. Therefore, determining if an acute bout of foam rolling self-myofascial release in addition to a dynamic warm-up could influence performance is of importance. In order to do so, eleven athletically trained male subjects participated in a two condition, counterbalanced, crossover within-subjects study comparing two particular warm-up routines. The two warm-up routines compared were ...


The Physiologic And Behavioral Implications Of Playing Active And Sedentary Video Games In A Seated And Standing Position, Gabriel J. Sanders, Michael Rebold, Corey A. Peacock, Megan L. Williamson, Antonio Santo, Jacob E. Barkley 2014 Western Kentucky University

The Physiologic And Behavioral Implications Of Playing Active And Sedentary Video Games In A Seated And Standing Position, Gabriel J. Sanders, Michael Rebold, Corey A. Peacock, Megan L. Williamson, Antonio Santo, Jacob E. Barkley

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 194-201, 2014. Previous studies have assessed physiologic response while playing video games per manufacturer instructions with participants standing during active video game play and seated during sedentary game play. It is not known whether an assigned seated or standing position affects positional preference and oxygen consumption (VO2) while gaming. The purpose of the study was to assess VO2 and preference of playing active and sedentary video games in a seated and standing position. VO2 was assessed in 25 participants during four, 20-minute conditions; resting, PlayStation 2 Madden NFL Football 2011, Nintendo Wii-Sports Boxing ...


Effect Of Long-Term Physical Exercise On Blood Pressure In African Americans, Taunjah P. Bell, Katharine A. McIntyre, Rosamary Hadley 2014 Western Kentucky University

Effect Of Long-Term Physical Exercise On Blood Pressure In African Americans, Taunjah P. Bell, Katharine A. Mcintyre, Rosamary Hadley

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 186-193, 2014. Long-term physical exercise has been shown to noticeably reduce blood pressure (BP) and remarkably attenuate symptoms of hypertension. It is believed that physical exercise induces these beneficial effects by increasing the blood supply to the brain, enhancing the release of growth factors from skeletal muscles into the bloodstream, facilitating neurogenesis, stimulating angiogenesis, and influencing endothelial cell proliferation and subsequent endothelial cell membrane permeability. Previous findings also revealed that physical exercise significantly elevates brain-derived neurotrophic factor (BDNF) concentrations which appear to increase dramatically in BP-sensing neurons during hypertension. Elevating BDNF levels is ...


Cardiovascular And Metabolic Demands Of The Kettlebell Swing Using A Tabata Interval Versus A Traditional Resistance Protocol, Howard A. Fortner, Jeanette Salgado, Angelica M. Holmstrup, Michael E. Holmstrup PhD 2014 Western Kentucky University

Cardiovascular And Metabolic Demands Of The Kettlebell Swing Using A Tabata Interval Versus A Traditional Resistance Protocol, Howard A. Fortner, Jeanette Salgado, Angelica M. Holmstrup, Michael E. Holmstrup Phd

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 179-185, 2014. Tabata (TAB) training, consisting of eight cycles of 20 seconds of maximal exercise followed by 10 seconds of rest, is time-efficient, with aerobic and anaerobic benefit. This study investigated the cardiovascular and metabolic demands of a TAB versus traditional (TRAD) resistance protocol with the kettlebell swing. Fourteen young (18-25y), non-obese (BMI 25.7±0.8 kg/m2) participants reported on three occasions. All testing incorporated measurements of HR, oxygen consumption, and blood lactate accumulation. Each participant completed Tabata kettlebell swings (male- 8kg, female- 4.5kg; 8 intervals; 20s maximal repetitions ...


Is There An Optimal Whole-Body Vibration Exposure ‘Dosage’ For Performance Improvement?, R Hugh Morton, Darryl J. Cochrane 2014 Western Kentucky University

Is There An Optimal Whole-Body Vibration Exposure ‘Dosage’ For Performance Improvement?, R Hugh Morton, Darryl J. Cochrane

International Journal of Exercise Science

International Journal of Exercise Science 7(3) : 169-178, 2014. Whole-body vibration exposure has been shown to improve performance in vertical jumping and knee extensions. Some studies have addressed the question of dose optimality, but are inconclusive and inappropriately designed. Our purpose was to more thoroughly seek an optimum combination of duration, amplitude and frequency of exposure to side-alternating whole-body vibration. We used experimental designs constructed for response surface fitting and optimisation, using both blocked and unblocked second order central composite designs with 12 participants. Immediately after each exposure a discomfort index was recorded, then peak and average torque, peak and ...


Pathscan Enabler At Md Anderson Cancer Center, George McNamara 2014 The University of Texas

Pathscan Enabler At Md Anderson Cancer Center, George Mcnamara

George McNamara

McNamara 20140703 - Additional Pathscan and Tiki_Goddess related resources

http://works.bepress.com/gmcnamara/52

http://home.earthlink.net/~tiki_goddess/

http://works.bepress.com/gmcnamara/1/

http://works.bepress.com/gmcnamara/11/

https://www.linkedin.com/in/georgemcnamara

Our Pathscan Enabler IV, delivered July 2014, uses the QuickScan software to scan a histology slide in "two clicks" (after loading the

slide):

1. Push the QuickScan button on the front of the Pathscan Enabler.

2. Click the Scan button in the QuickScan pop-up application (optional: change scan area in the Prescan image window).

The image gets saved as a TIFF file to ...


The Bcl-2 Family Protein Bid Is Critical For Pro-Inflammatory Signaling In Astrocytes., Hans-Georg König, Karen S. Coughlan, Sinéad Kinsella, Bridget A. Breen, Jochen HM Prehn 2014 Royal College of Surgeons in Ireland

The Bcl-2 Family Protein Bid Is Critical For Pro-Inflammatory Signaling In Astrocytes., Hans-Georg König, Karen S. Coughlan, Sinéad Kinsella, Bridget A. Breen, Jochen Hm Prehn

Physiology and Medical Physics Articles

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motoneurons in the spinal cord, brainstem and motor cortex. Mutations in the superoxide dismutase 1 (SOD1) gene represent a frequent genetic determinant and recapitulate a disease phenotype similar to ALS when expressed in mice. Previous studies using SOD1(G93A) transgenic mice have suggested a paracrine mechanism of neuronal loss, in which cytokines and other toxic factors released from astroglia or microglia trigger motoneuron degeneration. Several pro-inflammatory cytokines activate death receptors and may downstream from this activate the Bcl-2 family protein, Bid. We here sought to investigate ...


Calmodulation Meta-Analysis: Predicting Calmodulin Binding Via Canonical Motif Clustering, Karen Mruk, Brian M. Farley, Alan W. Ritacco, William R. Kobertz 2014 University of Massachusetts Medical School

Calmodulation Meta-Analysis: Predicting Calmodulin Binding Via Canonical Motif Clustering, Karen Mruk, Brian M. Farley, Alan W. Ritacco, William R. Kobertz

Biochemistry and Molecular Pharmacology Publications and Presentations

The calcium-binding protein calmodulin (CaM) directly binds to membrane transport proteins to modulate their function in response to changes in intracellular calcium concentrations. Because CaM recognizes and binds to a wide variety of target sequences, identifying CaM-binding sites is difficult, requiring intensive sequence gazing and extensive biochemical analysis. Here, we describe a straightforward computational script that rapidly identifies canonical CaM-binding motifs within an amino acid sequence. Analysis of the target sequences from high resolution CaM-peptide structures using this script revealed that CaM often binds to sequences that have multiple overlapping canonical CaM-binding motifs. The addition of a positive charge discriminator ...


Vitamin A Deficiency Causes Ovulation Abnormalities In Mice, Rebecca Ursin 2014 DePaul University

Vitamin A Deficiency Causes Ovulation Abnormalities In Mice, Rebecca Ursin

DePaul Discoveries

Retinoic acid (RA) is an active metabolite of vitamin A (VA) and is involved in tissue organization, patterning, and growth. RA has been shown to regulate male reproduction, however information on its role in ovary development is limited. To investigate the functions of RA in the ovary, we examined its role in ovary development and ovulation using an in vivo dietary VA-deprivation animal model. Our preliminary results have shown that VA deficiency causes a variety of ovarian pathologies, including reduced numbers of total follicles and corpus lutea, formation of hemorrhagic and atretic follicles, and formation of bursa and follicular cysts ...


Effects Of Plyometric And Endurance Training On Aerobic And Anaerobic Power., T. Snyder, E. Shaw, A. Mueller, E. Stoeckel, A. Strom, T. VanDerVeeken, T. Swensen 2014 Western Kentucky University

Effects Of Plyometric And Endurance Training On Aerobic And Anaerobic Power., T. Snyder, E. Shaw, A. Mueller, E. Stoeckel, A. Strom, T. Vanderveeken, T. Swensen

International Journal of Exercise Science: Conference Proceedings

Snyder, T., Shaw, E., Mueller, A., Stoeckel, E., Strom, A., VanDerVeeken, T., Swensen, T., Exercise and Sport Sciences, Ithaca College, Ithaca NY

Purpose and Methods: Extending the work of Burgomaster and Gibala, we compared the effects of four weeks of plyometric and endurance training on various indices of aerobic and anaerobic performance in 29 active college age males and females (19.4 ± 1.8 years and 69.9 ± 13.8 kg), who were assigned to a plyometric (6 males and 9 females) or endurance training group (6 males and 8 females). Endurance training consisted of 30 min of cycling at ...


The Effects Of Various Recovery Techniques On Collegiate Pitching Performance, B. Snyder, S. Davis, G. Moir, M. Miltenberger 2014 Western Kentucky University

The Effects Of Various Recovery Techniques On Collegiate Pitching Performance, B. Snyder, S. Davis, G. Moir, M. Miltenberger

International Journal of Exercise Science: Conference Proceedings

Snyder, B., Davis, S., Moir, G., Miltenberger, M., East Stroudsburg University, East Stroudsburg, PA

Purpose: This study was designed to compare pitching performance (velocity, accuracy), symptomology and functional movement across three recovery techniques (active recovery (pedaling on a stationary bike at 40% Max Age Predicted Heart Rate), passive recovery (sitting down with a jacket around the pitchers arm), and Electro muscular stimulation (sitting down with stim placed on the pitchers arm at the anterior and posterior deltoid) in NCAA Division II collegiate pitchers. Methods: Eight male Division II collegiate baseball athletes (Age: 20.1 ± 1.7 years, Mass: 84.8 ...


Ventilatory Threshold Responses At Different Percentages Of Body Weight On The Alter-G Anti-Gravity Treadmill: A Pilot Study, N. Santillo, M. Figueroa, T. Lasala, J. Manning 2014 Western Kentucky University

Ventilatory Threshold Responses At Different Percentages Of Body Weight On The Alter-G Anti-Gravity Treadmill: A Pilot Study, N. Santillo, M. Figueroa, T. Lasala, J. Manning

International Journal of Exercise Science: Conference Proceedings

Santillo, N., Figueroa, M., Lasala, T., Manning, J., William Paterson University, Wayne NJ

Purpose: The purpose of this study was to determine if changes occurred in the ventilatory threshold (VT) upon manipulation of body weight (BW) when comparing 80% to 100% of BW in healthy college aged individuals on the Alter-G® anti-gravity treadmill. Methods: A modified Bruce Protocol was used to measure oxygen consumption (VO2peak) on 10 subjects (5 males, 5 females) at 100%, and 80% of BW. Testing protocols were randomized with two weeks in between each test. VT was determined by the software algorithm in the MedGraphics ...


Examination Of Exercise Behaviors, Exercise Barriers And Exercise Self-Efficacy Of British Adults, M. Sadler, M. Brown, K. Dugan, J. Litchauer, K. Port, K. Smith 2014 Western Kentucky University

Examination Of Exercise Behaviors, Exercise Barriers And Exercise Self-Efficacy Of British Adults, M. Sadler, M. Brown, K. Dugan, J. Litchauer, K. Port, K. Smith

International Journal of Exercise Science: Conference Proceedings

Sadler, M., Brown, M., Dugan, K., Litchauer, J., Port, K., Smith, K., Slippery Rock University, Slippery Rock, PA

Purpose: To examine the exercise behaviors, barriers and self-efficacy of British adults. Methods: A survey was constructed based upon previously validated questionnaires and was randomly administered to subjects in various British cities. Seventy nine subjects, with a mean age of 31.92+12.03 participated in this study. Results: Subjects reported engaging in vigorous physical activity 3.5+2.94 days/week. The table below illustrates the modes of exercise regularly performed by the subjects. Subjects could report participating in more than ...


Effect Of Beta-Adrenergic Blockade On Coronary Blood Flow During Isometric Exercise In Older Adults, A. Ross, Z. Gao, M. Heffernan, U. Leuenberger, L. Sinoway, M. Muller 2014 Western Kentucky University

Effect Of Beta-Adrenergic Blockade On Coronary Blood Flow During Isometric Exercise In Older Adults, A. Ross, Z. Gao, M. Heffernan, U. Leuenberger, L. Sinoway, M. Muller

International Journal of Exercise Science: Conference Proceedings

Ross A., Gao Z., Heffernan M., Leuenberger U., Sinoway L., Muller M. Penn State Hershey Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, PA

The rise in heart rate (HR) and cardiac contractility during exercise is due to activation of myocardial b-adrenergic receptors. b-receptors are also located on coronary blood vessels and are thought to participate in exercise hyperemia, thereby helping to preserve the balance between myocardial oxygen supply and demand. However, experimental data in human subjects are lacking. Purpose: We hypothesized that intravenous b-adrenergic blockade would attenuate the reflex tachycardia and coronary hyperemia in response to ...


Comparison Of Young And Functional Fit Older Adults On Temporal Spatial Gait Parameters, S. Paulson, M. Gray 2014 Western Kentucky University

Comparison Of Young And Functional Fit Older Adults On Temporal Spatial Gait Parameters, S. Paulson, M. Gray

International Journal of Exercise Science: Conference Proceedings

1Paulson, S., 2Gray, M. 1Shippensburg University, Shippensburg, PA; 2University of Arkansas, Fayetteville, AR

Gait speed (GS) has been recognized as an integral component of functional independence. Further, step length (SL), cadence (CAD) and the percentage of the gait cycle in spent in stance (%ST) have been associated with risk of falls and mobility disability among older adults. Purpose: This study examined temporal spatial gait variables in young and low and high functionally fit older adults. Methods: Twenty older and 12 younger adults (CON; M±SD = age: 22.3±1.8, height 1.7±0.1 m ...


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