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3,435 full-text articles. Page 1 of 123.

Patient-Specific Inference Of Average Glucose From Glycated Hemoglobin, Roy Malka, David M. Nathan, John M. Higgins 2016 Massachusetts General Hospital

Patient-Specific Inference Of Average Glucose From Glycated Hemoglobin, Roy Malka, David M. Nathan, John M. Higgins

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Modeling Of Endotoxin-Induced Inflammation In Young Men, Renee Brady 2016 North Carolina State University at Raleigh

Mathematical Modeling Of Endotoxin-Induced Inflammation In Young Men, Renee Brady

Biology and Medicine Through Mathematics Conference

No abstract provided.


Hill's Diagrammatic Method And Reduced Graph Powers, Gregory D. Smith, Richard Hammack 2016 The College of William & Mary

Hill's Diagrammatic Method And Reduced Graph Powers, Gregory D. Smith, Richard Hammack

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Theoretical Model Of The Increase In Venous Oxygen Saturation Levels In Advanced Glaucoma Patients, Julia C. Arciero 2016 IUPUI

A Theoretical Model Of The Increase In Venous Oxygen Saturation Levels In Advanced Glaucoma Patients, Julia C. Arciero

Biology and Medicine Through Mathematics Conference

No abstract provided.


Exosomes Derived From Alcohol-Treated Hepatocytes Horizontally Transfer Liver Specific Mirna-122 And Sensitize Monocytes To Lps, Fatemeh Momen-Heravi, Shashi Bala, Karen Kodys, Gyongyi Szabo 2016 University of Massachusetts Medical School

Exosomes Derived From Alcohol-Treated Hepatocytes Horizontally Transfer Liver Specific Mirna-122 And Sensitize Monocytes To Lps, Fatemeh Momen-Heravi, Shashi Bala, Karen Kodys, Gyongyi Szabo

Gyongyi Szabo

Hepatocyte damage and inflammation in monocytes/macrophages are central to the pathogenesis of alcoholic hepatitis (AH). MicroRNAs (miRNAs) regulate all of these processes. MiRNA-122 is abundantly expressed in hepatocytes while monocytes/macrophages have low levels. The role of exosomes in AH and possible cross talk between hepatocyte-derived exosomes and immune cells is not explored yet. Here, we show that the number of exosomes significantly increases in the sera of healthy individuals after alcohol binge drinking and in mice after binge or chronic alcohol consumption. Exosomes isolated from sera after alcohol consumption or from in vitro ethanol-treated hepatocytes contained miRNA-122. Exosomes ...


Connecting The Physiological And Behavioral Response To Heat Stress On A Warming Planet, Anastasia Kalyta 2016 Chapman University

Connecting The Physiological And Behavioral Response To Heat Stress On A Warming Planet, Anastasia Kalyta

Student Research Day Abstracts and Posters

Intertidal communities are considered good models of the biological effects of climate change on ecosystems, as their resident organisms are subjected to heat spells during daytime low tides. The increasing heat exposure can elicit behavioral as well as physiological responses in intertidal organisms. We studied the relationship between these responses to heat stress in the blue-banded hermit crab, Pagurus samuelis, by inducing a “heat shock” with elevated water temperature of 29 °C for 2.5 h. The behavioral effect of heat-shock was quantified using a 30-minute feeding assay, measuring the mass of a standard squid pellet consumed by individual hermit ...


Effects Of Cognitive Fatigue On High Intensity Circuit Exercise: Preliminary Study, A J. Tweedell, J R. Head, M. S. Tenan, H C. Davis, M. LaFiandra, W S. Helton 2016 Army Research Laboratory

Effects Of Cognitive Fatigue On High Intensity Circuit Exercise: Preliminary Study, A J. Tweedell, J R. Head, M. S. Tenan, H C. Davis, M. Lafiandra, W S. Helton

International Journal of Exercise Science: Conference Proceedings

Please refer to the pdf version of the abstract located adjacent to the title.


Handwashing: A Study Of The History, Methods, And Psychology Surrounding Hand Hygiene, Daniel J. Remillard 2016 Liberty University

Handwashing: A Study Of The History, Methods, And Psychology Surrounding Hand Hygiene, Daniel J. Remillard

Senior Honors Theses

This paper covers three different areas concerning handwashing. First a review of the history of handwashing is done, going from ancient times to its introduction into modern medicine via Dr. Ignaz Semmelweis. This section gives a sobering reminder not to instantly reject data that comes in conflict with prevalent thought.

Then current medical knowledge about handwashing is examined, and the conclusion reached states that handwashing is best done with non-antibacterial soap.

Finally, a review of the psychology of handwashing shows that medical professionals often tend toward neglect if unwatched and unmotivated by an outside source. However, those suffering from obsessive ...


Gene Profiling Of Early And Advanced Liver Disease In Chronic Hepatitis C Patients., Saira Sarfraz Khalid, Saeed Hamid, Anwar Ali Siddiqui, Asaf Qureshi, Nilofer Qureshi 2016 Aga Khan University

Gene Profiling Of Early And Advanced Liver Disease In Chronic Hepatitis C Patients., Saira Sarfraz Khalid, Saeed Hamid, Anwar Ali Siddiqui, Asaf Qureshi, Nilofer Qureshi

Anwar Ali Siddiqui

Purpose: Strong impact of hepatitis C virus (HCV) on normal regulation of cellular processes has been reported that could have significant implications for HCV pathogenesis. We aimed to determine the altered cellular processes during HCV infection with particular reference to advanced disease stages. Methods: Liver biopsy specimens of chronic hepatitis C Patients classified on histological basis as early (fibrosis stage 1-2) or advanced (fibrosis stage 3-4) HCV disease were studied using microarray technology (Affymetrix GeneChip System). For comparison, liver specimens from Patients with non-viral hepatitis (NV-hepatitis) were also analyzed by microarray. Expression data generated were analyzed using software Genespring GX ...


The Thioredoxin Trx-1 Regulates The Major Oxidative Stress Response Transcription Factor, Skn-1, In Caenorhabditis Elegans, Katie C. McCallum 2016 The University of Texas Graduate School of Biomedical Sciences at Houston

The Thioredoxin Trx-1 Regulates The Major Oxidative Stress Response Transcription Factor, Skn-1, In Caenorhabditis Elegans, Katie C. Mccallum

UT GSBS Dissertations and Theses (Open Access)

The ability to respond to hostile environmental conditions is critical for the survival of an organism. Oxidative stress is an adverse state in which reactive oxygen species (ROS) accumulate to a harmful level and, if left unresolved, can lead to cellular dysfunction and organismal disease. Sophisticated detoxification systems, characterized by a battery of enzymatic antioxidants, are utilized to neutralize ROS thereby reducing stress. However, ROS are also purposefully produced by designated cellular enzymes to facilitate the signaling and regulation of critical physiological processes. Therefore, both the production and neutralization of ROS must be tightly controlled. Indeed, the expression of detoxification ...


Transition Between Phases Of The Annual Cycle: Spring Migration To Breeding In Nearctic-Neotropical Songbirds, Kristen Marie Covino 2016 University of Southern Mississippi

Transition Between Phases Of The Annual Cycle: Spring Migration To Breeding In Nearctic-Neotropical Songbirds, Kristen Marie Covino

Dissertations

Appropriate timing of each life-history stage is crucial for seasonally migratory species. The temporal constraints faced by migratory songbirds require that they overlap preparation for breeding with spring migration. However, previous work has focused primarily on male birds and has produced inconsistent results regarding the degree of overlap between these two life-history stages. I study the degree to which migrating male and female songbirds prepare for breeding throughout spring migration as they move towards their breeding grounds. Overall, male migrants show a significant degree of breeding preparation during spring migration as determined by circulating testosterone levels and their ability to ...


Validation Of The Use Of Doubly Labeled Water For Measuring Metabolic Rate In Timber Rattlesnakes (Crotalus Horridus), Caitlin Hirsh 2016 University of Arkansas Fayetteville

Validation Of The Use Of Doubly Labeled Water For Measuring Metabolic Rate In Timber Rattlesnakes (Crotalus Horridus), Caitlin Hirsh

Biological Sciences Undergraduate Honors Theses

The doubly labeled water method is an isotopic technique for measuring field metabolic rate and water flux rates of free-living animals. We present a validation of the use doubly labeled water for measuring metabolic rate and water loss in Timber Rattlesnakes (Crotalus horridus). For this study seven animals of varying body size were used with masses ranging from 148 to 650 grams. Prior to dosing, blood samples were taken to establish background isotope levels for each animal. Snakes were injected with water enriched with isotopes of oxygen (18O) and hydrogen (2H, deuterium). The injected isotopes were then allowed to equilibrate ...


Bleeding Keaney Blue: An Analysis Of Sports Fandom And The Supporters Of Uri Basketball, Lia M. Moceri 2016 University of Rhode Island

Bleeding Keaney Blue: An Analysis Of Sports Fandom And The Supporters Of Uri Basketball, Lia M. Moceri

Senior Honors Projects

In the United States, sports are so prevalent on the national, state, and local level that researchers assert they have become a major component of everyday life. In fact, millions of Americans consider themselves sports fans. Studying sports fandom offers an interesting insight into the human condition.

This paper begins by looking at sports fans on a psychological level by examining socialization, the process of becoming a sports fan. It also examines the reasons people become fans and the degree to which people identify as a fan. An important psychological aspect when studying sports fans is identity and how a ...


Response Of Leukocyte Profiles To Corticosterone Manipulation In The Prairie Rattlesnake (Crotalus Viridus), Jill E. Guillette 2016 University of Arkansas, Fayetteville

Response Of Leukocyte Profiles To Corticosterone Manipulation In The Prairie Rattlesnake (Crotalus Viridus), Jill E. Guillette

Biological Sciences Undergraduate Honors Theses

Prior work has shown that when animals are stressed they have altered leukocyte profiles. The use of leukocyte profiles could provide an inexpensive and efficient method for determining stress. Here we present a validation of the use of leukocyte profiles for showing induced stress in Prairie Rattlesnakes (Crotalus viridus). Snakes (N=19) with masses ranging from 682g to 137g were used in a repeated measures design to examine the effect of hormone manipulation on leukocyte profiles. During each trial snakes were dosed with either corticosterone and sesame oil (1.1µg/g) or only sesame oil. Prior to dosing, baseline blood ...


Mini Series Presentations, Robert L. Moody IV, Natasha S. Natraj 2016 Otterbein University

Mini Series Presentations, Robert L. Moody Iv, Natasha S. Natraj

SYE Legacies: Student Group Projects

For the month of March, we implemented a mini education program at both EmblemHealth sites to engage, educate and empower members of the fitness center and weight management program. The program was designed to be fifteen minutes in length, allowing for more sessions over the course of 3 hours with one session a week alternating between topics. Upon survey evaluation of the 60 participants, they reported satisfaction with the overall program and validated the worth of EmblemHealth’s Fitness Center. The survey also showed that 10 out of 10 participants recognized sitting disease as a primary health concern after the ...


Na/K-Atpase Amplification Of Oxidant Stress; A Universal But Unrecognized Clinical Target?, Joseph I. Shapiro MD 2016 Marshall University

Na/K-Atpase Amplification Of Oxidant Stress; A Universal But Unrecognized Clinical Target?, Joseph I. Shapiro Md

Joseph I Shapiro MD

Schematic showing Na/K‐ATPase as reactive oxygen species (ROS) amplifier system. CTS‐cardiotonic steroids, Orange dimer is Na/K‐ATPase. pNaKtide refers to peptide formed from epitope of Na/K‐ATPase a1 subunit known to bind Src tyrosine kinase fused with TAT leader sequence.


Designing A Mobile Space Habitat Analog, Victor Kitmanyen, Matthew Burkhard, Timothy Disher 2016 Embry-Riddle Aeronautical University - Daytona Beach

Designing A Mobile Space Habitat Analog, Victor Kitmanyen, Matthew Burkhard, Timothy Disher

Human Factors and Applied Psychology Student Conference

No abstract provided.


Factors Affecting The Immune System Of The Ornate Box Turtle (Terrapene Ornata), Michelle W. McQuinn, Abigail A. Neyer, Gwendolyn C. Bachman 2016 University of Nebraska-Lincoln

Factors Affecting The Immune System Of The Ornate Box Turtle (Terrapene Ornata), Michelle W. Mcquinn, Abigail A. Neyer, Gwendolyn C. Bachman

UCARE Research Products

While many studies have detailed the complex intricacies of the endothermic immune system, relatively little is known about the immune system of ectotherms--specifically, reptiles. In an attempt to gain more knowledge about the factors affecting reptilian immune function, ornate box turtles (Terrapene ornata) were subjected to chronic stress in the form of high ambient temperatures in a semi-natural environment. It was hypothesized that chronic stress would lead to elevated levels of corticosterone in the blood, which would, in turn, suppress immune activity. It was found that body temperature and body mass in particular were significantly affected by chronic heat stress ...


The Effect Of Training Intensity On Vo2max In Young Healthy Adults: A Meta-Regression And Meta-Analysis, Trisha Scribbans, Stephan Vecsey, Hankinson Paul, William Foster, Brendon Gurd 2016 Queen's University - Kingston, Ontario

The Effect Of Training Intensity On Vo2max In Young Healthy Adults: A Meta-Regression And Meta-Analysis, Trisha Scribbans, Stephan Vecsey, Hankinson Paul, William Foster, Brendon Gurd

International Journal of Exercise Science

International Journal of Exercise Science 9(2): 230-247, 2016. Exercise training at a variety of intensities increases maximal oxygen uptake (VO2max), the strongest predictor of cardiovascular and all-cause mortality. The purpose of the present study was to perform a systematic review, meta-regression and meta-analysis of available literature to determine if a dose-response relationship exists between exercise intensity and training-induced increases in VO2max in young healthy adults. Twenty-eight studies involving human participants (Mean age: 23±1 yr; Mean VO2max: 3.4±0.8 l·min−1) were included in the meta-regression with exercise training intensity, session dose, baseline VO2max, and total ...


Metabolic And Energy Cost Of Sitting, Standing, And A Novel Sitting/Stepping Protocol In Recreationally Active College Students, Charles J. Fountaine, Josh Johann, Craig Skalko, Gary A. Liguori 2016 University of Minnesota Duluth

Metabolic And Energy Cost Of Sitting, Standing, And A Novel Sitting/Stepping Protocol In Recreationally Active College Students, Charles J. Fountaine, Josh Johann, Craig Skalko, Gary A. Liguori

International Journal of Exercise Science

International Journal of Exercise Science 9(2): 223-229, 2016. The purpose of this study was to compare the differences in metabolic and energy cost (MEC) of college students while seated, standing, and during a sitting/stepping protocol. Participants were assessed via indirect calorimetry for 20 min in each of the following conditions: 1) seated in a standard office chair, 2) standing in place, and 3) a sitting/stepping protocol in which participants performed 1 min of stepping in place at 90 bpm, sat for 9 min, then repeated the stepping and sitting sequence once more. Participants completed each of the ...


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