Physiology Commons^™

The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey

Senior Theses and Capstone Projects

Type 1 Diabetics have various ways of managing their diabetes that have been studied for their effectiveness. Pregnancy in the Type 1 Diabetic has been understudied. It is known that Diabetics in general have poorer pregnancy outcomes because of poor glycemic control. This coupled with the fact that the body needs 3-4 times more insulin as pregnancy comes to an end makes managing blood glucose levels challenging for diabetics (Lowdermilk, 2016, p. 689). For the Type 1 Diabetic, there are two main ways to control diabetes: multiple daily injections using at least two type of insulin and continuous subcutaneous insulin ...

Greater Polar Moment Of Inertia At The Tibia In Athletes Who Develop Stress Fractures, Lee A. Weidauer, Teresa Binkley, Matthew Vukovich, Bonny Specker

Matthew Vukovich

Background: Several previous investigations have determined potential risk factors for stress fractures in athletes and military personnel. Purpose: To determine factors associated with the development of stress fractures in female athletes. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 88 female athletes (cross-country, n ¼ 29; soccer, n ¼ 15; swimming, n ¼ 9; track and field, n ¼ 14; volleyball, n ¼ 12; and basketball, n ¼ 9) aged 18 to 24 years were recruited to participate in a longitudinal bone study and had their left distal tibia at the 4%, 20%, and 66% sites ...

Heads And Tails, Julie Simons

Annual Symposium on Biomathematics and Ecology: Education and Research

No abstract provided.

Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O'Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson

Journal Articles: Cellular & Integrative Physiology

Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although MTX reduces systemic inflammation and tissue damage, the mechanisms by which MTX exerts these beneficial effects are not entirely known. We have previously demonstrated that protein adducts formed by the interaction of malondialdehyde (MDA) and acetaldehyde (AA), known as MAA-protein adducts, are present in diseased tissues of individuals with rheumatoid arthritis (RA) or CVD. In previously reported studies, MAA-adducts were shown to be highly immunogenic ...

Physiological Ecology Of Four Endemic Alabama Species And The Exotic Asiatic Weatherfish, Misgurnus Anguillicaudatus (Cantor, 1842), Lindsay M. White, Mark E. Meade, Benjamin A. Staton

Southeastern Fishes Council Proceedings

The occurrence of Asiatic Weatherfish, Misgurnus anguillicaudatus, in Alabama, a state known for its rich biodiversity, has generated concern among conservation managers. The current study used respirometry techniques to investigate the effects of increasing temperature on four native southeastern fishes (one cyprinid, two percids, and one elassomid) and the non-native M. anguillicaudatus. A minimum of five individuals of each species were used, and three experimental temperatures were chosen to represent spring and summer averages of northeast Alabama streams (15, 20, and 25°C). Overall, mean standard metabolic rates (SMRs) for M. anguillicaudatus were low (97.01, 127.75, and 158 ...

The Relationship Between Athletic Identity And Academic Major Chosen By Student-Athletes, Sayvon Jl Foster, Matt R. Huml

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 915-925, 2017. This study examines the correlation between athletic identity and academic major selection among intercollegiate student-athletes. A thorough review of literature focusing on academic clustering, athletic identity, and academic development leads to the development of two hypotheses – 1) student-athletes with stronger athletic identity will have a declared major of decreased academic rigor; and 2) student-athletes with stronger athletic identity will be more likely to be undecided on their major. Data were collected through a survey administered to Division I, II, and III student-athletes recording academic major and their Athletic Identity Measurement Scale ...

Corporate Social Responsibility: Considerations For Sport Management In The Age Of Neoliberalism, Anthony J. Weems, Justin R. Garner, Kristi Oshiro, John N. Singer

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 900-914, 2017. For financial reasons, in efforts to maintain legitimacy, and in response to social pressures, sport organizations increasingly engage with corporate social responsibility (CSR). However, with the rise of global neoliberalism, the logic of CSR can be problematic. In this essay, we provide a brief overview, critique, and reconstruction of CSR in the sport industry. Specifically, we call into question three popularized forms of CSR: (1) diversity, inclusion, and diversity management, (2) environmental responsibility, and (3) health and physical activity-based initiatives. In a neoliberal context, CSR in sport provides, at best, a ...

From Crisis To De-Escalation: An Examination Of Politics In A U.S. High School Steroid Testing Program, Brennan K. Berg, Kathryn Winsley, Rhema D. Fuller, Michael Hutchinson

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 890-899, 2017. Preventing the use of performance enhancing drugs in sport has long been a concern for policymakers. In the United States, amidst national attention the state of Texas constructed the country’s largest steroid testing program for high school athletes. However, resource allocation steadily declined until the program was defunded in 2015. Using escalation of commitment theory as a framework, this conceptual paper examines the critical, but less studied, role of politics and de-escalation behavior that directed this distinct sport situation. By combining policy and media documents with the academic literature, this ...

Coaches’ Perception Of Organizational Socialization Process Of International Student-Athletes And The Effect Of Cultural Distance: An Exploratory Study., Evelyn S. Jara-Pazmino, Bob Heere, Tom H. Regan, Christine E. Blake, Richard Southall

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 875-889, 2017. This study focuses on the coaches’ perspective of the organizational socialization process of new international student-athletes. After analyzing the information of 10 in-depth interviews with experienced NCAA Division I coaches, this exploratory study aided the researchers to identify socialization tactics being used to successfully integrate international student-athletes entering USA college teams. ISAs come from different cultures, and pending on their home nation culture they might be challenged in their ability to socialize within their new surroundings. Results indicate that the cultural distance between team culture and ISA’s culture affects the ...

Cultural Values And Gender Equity On National Olympic Committee Boards, Na Young Ahn, George B. Cunningham

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 857-874, 2017. Women are under-represented in leadership positions throughout sport, and researchers have largely explored organizational, group, and individual antecedents of this phenomenon. The purpose of the current study was to expand on this understanding by investigating the influence of a country’s cultural values on the representation of women on National Olympic Committees. Drawing from Hofstede’s cultural dimensions theory, the authors included five cultural values: power distance, uncertainty avoidance, individualism-collectivism, masculinity-femininity, and long-term orientation. Results indicate that women constituted only 19.7 percent of the positions on the boards. Regression analysis ...

“I Will Change The World”: The Intersection Of Social Change And Male College Athletes’ Leadership Perspectives, Rhema D. Fuller, C. Keith Harrison, S. Malia Lawrence, Jeff Eyanson, Danielle Mccardle

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 845-856, 2017. Historically, men have been characterized as task-oriented leaders who are motivated by desires for autonomy, wealth, and power (17, 33). However, these “masculine” views of leadership might not accurately capture the leadership motivations of Millennial males as the views were developed in previous generations (4). Given the commitment of many Millennials towards socially responsible attitudes and behaviors (18, 25), we utilized a qualitative research design to examine the influence of social change on the leadership motivations of Millennial male intercollegiate athletes. In doing so, we found participants were motivated to lead ...

Are You Welcomed? A Racial And Ethnic Comparison Of Perceived Welcomeness In Sport Participation, Trevor Bopp, Robert Turick, Joshua D. Vadeboncoeur, Thomas J. Aicher

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 833-844, 2017. Sport has become racialized such that minority youth accrue limited health and academic benefits from participation, compared to their White counterparts. Understanding the welcomeness that minorities feel in sport, leisure and physical activities plays an important role in breaking down barriers to participation. Thus, the overall aim of this study is to further examine the determinants of sport participation, particularly as it relates to race, socialization and perceived welcomeness. College students (N = 451) scored their perceived level of welcomeness for Whites, African Americans and Hispanic/Latinos in 14 sports. Results reveal ...

Does Time Heal All Wounds? A Case Study On Rival Perceptions Before And After Conference Realignment, Cody T. Havard, Daniel L. Wann, Timothy D. Ryan, Norman O'Neal

International Journal of Exercise Science

International Journal of Exercise Science 10(6): 823-832, 2017. The current longitudinal case study investigated how conference realignment and beginning new annual competitions impacted fan rival perceptions for fans of the Texas A&M Aggies, Missouri Tigers, and Texas Christian University Horned Frogs. In particular, fan rival perceptions before and after conference realignment were compared to determine if significant differences were present. Findings indicate that history plays an important role in rivalry as fans of teams sharing long-standing rivalries with schools in their previous conference (i.e., Texas A&M/Texas and Missouri/Kansas) did not differ in their rival ...

The Musicality Of The Water Lilies/La Musicalité Des Nymphéas (Library Resources), Holy Cross Libraries

Library Resources for Campus Events

A bibliography of resources available through the Holy Cross Libraries which provide additional information related to the Iris and B. Gerald Cantor Art Gallery exhibition “Gabrielle Thierry: The Musicality of the Water Lilies/La Musicalité des Nymphéas” from Aug. 30 through Oct. 7.

Thierry’s series of eight large-scale paintings were inspired by her rediscovery of the “Water Lilies” landscapes by Claude Monet on view at the the Musée de l’Orangerie in Paris. With special permission from the museum, Thierry painted in front of Monet’s originals over a period of 18 months from 2010 to 2012, where she ...

Energy Balance During A Self-Sufficient, Multistage Ultramarathon, Paul A. Hough, James Earle

Journal of Human Performance in Extreme Environments

Endurance athletes are recommended to maintain energy balance and ensure adequate energy availability (EA) so that endurance performance is not compromised. Purpose: Describe and evaluate the energy balance of an athlete competing in a self-sufficient, multistage ultramarathon (MSU). Methods: A male endurance athlete (age 35 years; height 183.0 cm; body mass 78.4 kg; VO_2max 66 ml/kg/min) volunteered to take part in this observational case study prior to competing in the Marathon des Sables (MdS) 2016. The subject self-reported energy intake (EI) by reviewing his dietary plan following each stage. Basal metabolic rate (BMR) was estimated ...

Temporal Changes In Cortical And Hippocampal Expression Of Genes Important For Brain Glucose Metabolism Following Controlled Cortical Impact Injury In Mice, June Zhou, Mark Burns, Linda Huynh, Sonia Villapol, Daniel D. Taub, Juan M. Saavedra, Marc R. Blackman

Pharmacology and Physiology Faculty Publications

Traumatic brain injury (TBI) causes transient increases and subsequent decreases in brain glucose utilization. The underlying molecular pathways are orchestrated processes and poorly understood. In the current study, we determined temporal changes in cortical and hippocampal expression of genes important for brain glucose/lactate metabolism and the effect of a known neuroprotective drug telmisartan on the expression of these genes after experimental TBI. Adult male C57BL/6J mice (n = 6/group) underwent sham or unilateral controlled cortical impact (CCI) injury. Their ipsilateral and contralateral cortex and hippocampus were collected 6 h, 1, 3, 7, 14, 21, and 28 days after ...

The N-Terminus Of Ift46 Mediates Intraflagellar Transport Of Outer Arm Dynein And Its Cargo-Adaptor Oda16, Yuqing Hou, George B. Witman

Radiology Publications and Presentations

Cilia are assembled via intraflagellar transport (IFT). The IFT machinery is composed of motors and multi-subunit particles, termed IFT-A and IFT-B, that carry cargo into the cilium. Knowledge of how the IFT subunits interact with their cargo is of critical importance for understanding how the unique ciliary domain is established. We previously reported a Chlamydomonas mutant, ift46-1, that fails to express the IFT-B protein IFT46, has greatly reduced levels of other IFT-B proteins, and assembles only very short flagella. A spontaneous suppression of ift46-1 restored IFT-B levels and enabled growth of longer flagella, but the flagella lacked outer dynein arms ...

The Role Of T-Box Proteins In Vertebrate Germ Layer Formation And Patterning, Sushma Teegala

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

All of the tissues in triploblastic organisms, with the exception of the germ cells, arise from the three germ layers, ectoderm, mesoderm and the endoderm. The identification of the genes that underlie the differentiation of these layers is crucial to our understanding of development. T-box family proteins are DNA-binding transcriptional regulators that play important roles during germ layer formation in the early vertebrate embryo. Well-characterized members of this family, including the transcriptional activators Brachyury and VegT, are essential for the proper formation of mesoderm and endoderm, respectively. To date, T-box proteins have not been shown to play a role in ...

Understanding Why Undergraduate Students Declare And Continue To Study An Exercise Science-Related Major, Matthew Vaartstra, Vanessa Kercher, Amanda Start, Amber Brown, Mark Peterson, Ryan Mcgrath

International Journal of Exercise Science

International Journal of Exercise Science 10(5): 807-817, 2017. Understanding factors that contribute to a student’s selection of an exercise science-related major is important to student success, higher education and industry. This study sought to 1) better understand why undergraduate students study an exercise science-related major, 2) determine whether positive influences to study an exercise science-related major differ by academic classification, and 3) identify what student’s aspirations are after graduation. Department administrators from four-year colleges and universities offering an exercise science-related major in the Northwest Region of the United States (i.e., Idaho, Montana, Oregon, and Washington) were ...

Blood Pressure And Cardiovascular Health Has Relationship With Age In Adults During Adulthood, Allyson K. Getty, Jessica M. Lenzo, Tia R. Wisdo, Joyann E. Oakman, Christina M. Cromwell, Jessica A. Hill, Lauren N. Chavis, Deborah L. Feairheller, Phd

International Journal of Exercise Science

International Journal of Exercise Science 10(5): 798-806, 2017. Efforts to combat cardiovascular disease (CVD) have proven effective, especially in the population aged 55-74 years. However, less research has been conducted in younger populations to determine at what age CVD risk develops. The purpose of this study is to compare cardiovascular health markers in adults, specifically CVD risk between younger adults aged 18-22 and a slightly older group of adults in middle adulthood aged 23-54. Cardiovascular health measures were collected from a group of adults; 13 younger adults (20.2±0.9 yrs) and 10 adults in middle adulthood (42 ...