. Interdisciplinary Teaching And Learning Within Molecular Gastronomy Education: Does It Benefit Students?, 2018 Dublin Institute of Technology
. Interdisciplinary Teaching And Learning Within Molecular Gastronomy Education: Does It Benefit Students?, Roisin Burke, Pauline Danaher
Since the creation of Molecular Gastronomy (MG) as a scientific discipline in 1988 a variety of higher education modules and programmes in that discipline have developed around the world. At the Dublin Institute of Technology, MG has been taught using an interdisciplinary approach since the academic year 2012/2013. A Culinary Science lecturer and a Culinary Arts lecturer work in synergy and teach an interdisciplinary group of Food Science (FS) and Culinary Arts (CA) students. The students’ work is assessed, in each academic year, using summative methods i.e. written exam and a project assignment. In the academic year 2016 ...
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, 2018 University of Nebraska at Omaha
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona
Student Research and Creative Activity Fair
Smoothened receptor (SMO) is a protein that in humans, is encoded by the SMO gene. A systemic mutation in its binding pocket helps predict the sensitivity of mutant proteins to different drugs. Known as a GPCR-like receptor, it is a component of the hedgehog signaling pathway; a pathway involved in body patterning and the regulation of adult stem cells. An uncontrolled or inappropriate activation of the Hedgehog pathway drives tumor progression in cancers and a number of birth defects. To achieve these goals, the molecular modeling software MOE was used to build small molecules and drug molecules like Vismodegib and ...
Integrating Students Into Interdisciplinary Health And Health Disparities Research Teams, 2018 University of North Carolina at Greensboro
Integrating Students Into Interdisciplinary Health And Health Disparities Research Teams, Tanya M. Coakley, Allyson Kelley, Robin Bartlett, Terri Shelton, Schenita D. Randolph, Debra C. Wallace
Journal of Health Disparities Research and Practice
Major initiatives by the U.S. Department of Health and Human Services as well as the World Health Organization have produced a large and compelling body of evidence on how to reduce health disparities, which entails having a clear understanding of how social factors shape health and healthcare outcomes. Specifically, there is a need for healthcare professionals to understand social determinants of health (e.g., low socioeconomic status, lack of health insurance, and poor education) and how these lead to disparities in health for people of minority racial and ethnic groups. Little is known about how students are developed as ...
Investigating Sociodemographic Disparities In Cancer Risk Using Web-Based Informatics, 2018 Biomedical Sciences, Engineering, and Computing Group Health Data Sciences Institute, Oak Ridge National Laboratory
Investigating Sociodemographic Disparities In Cancer Risk Using Web-Based Informatics, Hong-Jun Yoon, Georgia Tourassi
Journal of Human Performance in Extreme Environments
Cancer health disparities due to demographic and socioeconomic factors are an area of great interest in the epidemiological community. Adjusting for such factors is important when developing cancer risk models. However, for digital epidemiology studies relying on online sources such information is not readily available. This paper presents a novel method for extracting demographic and socioeconomic information from openly available online obituaries. The method relies on tailored language processing rules and a probabilistic scheme to map subjects’ occupation history to the occupation classification codes and related earnings provided by the U.S. Census Bureau. Using this information, a case-control study ...
Atomistic Simulations And Network-Based Modeling Of The Hsp90-Cdc37 Chaperone Binding With Cdk4 Client Protein: A Mechanism Of Chaperoning Kinase Clients By Exploiting Weak Spots Of Intrinsically Dynamic Kinase Domains, 2017 Chapman University
Atomistic Simulations And Network-Based Modeling Of The Hsp90-Cdc37 Chaperone Binding With Cdk4 Client Protein: A Mechanism Of Chaperoning Kinase Clients By Exploiting Weak Spots Of Intrinsically Dynamic Kinase Domains, John Czemeres, Kurt Buse, Gennady M. Verkhivker
Mathematics, Physics, and Computer Science Faculty Articles and Research
A fundamental role of the Hsp90 and Cdc37 chaperones in mediating conformational development and activation of diverse protein kinase clients is essential in signal transduction. There has been increasing evidence that the Hsp90-Cdc37 system executes its chaperoning duties by recognizing conformational instability of kinase clients and modulating their folding landscapes. The recent cryo-electron microscopy structure of the Hsp90-Cdc37- Cdk4 kinase complex has provided a framework for dissecting regulatory principles underlying differentiation and recruitment of protein kinase clients to the chaperone machinery. In this work, we have combined atomistic simulations with protein stability and network-based rigidity decomposition analyses to characterize dynamic ...
Virtual Reality As A Training Tool To Treat Physical Inactivity In Children, 2017 Cincinnati Children’s Hospital Medical Center
Virtual Reality As A Training Tool To Treat Physical Inactivity In Children, Adam W. Kiefer, David Pincus, Michael J. Richardson, Gregory D. Myer
Psychology Faculty Articles and Research
Lack of adequate physical activity in children is an epidemic that can result in obesity and other poor health outcomes across the lifespan. Physical activity interventions focused on motor skill competence continue to be developed, but some interventions, such as neuromuscular training (NMT), may be limited in how early they can be implemented due to dependence on the child’s level of cognitive and perceptual-motor development. Early implementation of motor-rich activities that support motor skill development in children is critical for the development of healthy levels of physical activity that carry through into adulthood. Virtual reality (VR) training may be ...
Science And Sentiment: Affecting Change In Environmental Awareness, Attitudes, And Actions Through The Daily Nature Project, Elizabeth D. Haynes Poronsky
The STEAM Journal
Knowledge about what motivates pro-environmental behavior is important to organizations that seek to encourage environmental stewardship. Research suggests that targeting emotions and beliefs about nature can be more effective in changing environmental actions than increasing knowledge. Daily Nature, a site on the social media platform Facebook, features a daily nature photograph, a quote from a notable historical person and a related lyrical written passage. The popularity of this site lends credence to the appeal of interdisciplinary formats, and underscores the benefits of encouraging emotional and aesthetic ties to nature.
Evaluation Of A Direct Pcr Method And The Qiagen Investigator 24plex Go! Kit For Typing Blood, Saliva And Touch Dna On Multiple Substrates, 2017 City University of New York (CUNY)
Evaluation Of A Direct Pcr Method And The Qiagen Investigator 24plex Go! Kit For Typing Blood, Saliva And Touch Dna On Multiple Substrates, Angelita Pierre-Noel
In forensic DNA typing, omitting the DNA extraction procedure and adding the sample directly to the polymerase chain reaction (direct PCR) mixture has several advantages. Without extraction and purification, there is less of a risk of sample loss, sample mix up, or contamination. This study tested the feasibility of direct PCR using the Qiagen® Investigator® 24plex GO! Kit, a megaplex kit that amplifies 22 polymorphic STR markers and the Amelogenin sex determination alleles. Test samples included blood, saliva and skin cells on porous substrates, specifically denim, white cotton, polyester fabric, and paper tissue. Glass slides were used to represent non-porous ...
Phytic Acid Protects Against 6-Hydroxydopamine-Induced Dopaminergic Neuron Apoptosis In Normal And Iron Excess Conditions In A Cell Culturemodel, 2017 Shanghai University of Traditional Chinese Medicine and Pharmacology
Phytic Acid Protects Against 6-Hydroxydopamine-Induced Dopaminergic Neuron Apoptosis In Normal And Iron Excess Conditions In A Cell Culturemodel, Qi Xu, Anumantha G. Kanthasamy, Manju B. Reddy
Manju B. Reddy
Iron may play an important role in Parkinson’s disease (PD) since it can induce oxidative stress-dependent neurodegeneration. The objective of this study was to determine whether the iron chelator, phytic acid (IP6) can protect against 6-hydroxydopamine- (6-OHDA-) induced apoptosis in immortalized rat mesencephalic dopaminergic cells under normal and iron-excess conditions. Caspase-3 activity was increased about 6-fold after 6-OHDA treatment (compared to control; P < .001) and 30 μmol/L IP6 pretreatment decreased it by 38% (P < .05). Similarly, a 63% protection (P < .001) against 6-OHDA induced DNA fragmentation was observed with IP6 pretreatment. Under iron-excess condition, a 6-fold increase in ...
Can Mine Reclamation With An Exotic Grass Species Precede Successful Restoration In Intermountain Grasslands? A Case Study With Agropyron Cristatum., Mark Mariano
Graduate Theses & Non-Theses
We performed four experiments to test whether or not native plants germinated with physical and chemical contact with crested wheatgrass (Agropyron cristatum (L.) Gaertn.), a grass species native to Eurasia which has been widely used for mine reclamation in North America. In our study area Butte, Montana, A. cristatum was planted on capped mine waste and, in many cases, has formed a monoculture with a large buildup of leaf litter. We found there to be a much higher mean litter depth on these lands when compared to wild grasslands. Leaf litter proved to be a significant barrier for the establishment ...
Beheading First: On Nabokov's Translation Of Lewis Carroll, 2017 Marshall University
Beheading First: On Nabokov's Translation Of Lewis Carroll, Victor Fet
Anya v Strane chudes, young Nabokov’s 1923 Russian translation of Alice’s Adventures in Wonderland, contains an intentionally shifted statement “beheading first, sentence later” compared to Lewis Carroll’s “sentence first, verdict later”. The shift is fitting for the 1920s children émigré audience.
Zoological Label As Literary Form, 2017 Marshall University
Zoological Label As Literary Form, Victor Fet
Nabokov’s work is seen through the unique concept of zoological labels and their language. A label, written by a young naturalist, is a concentrated source of information, detail, and “naming the unnamed”; it reflects three Aristotelian unities (place, time, action).
An Anti-Locust Campaign In Nabokov (And Pushkin), 2017 Marshall University
An Anti-Locust Campaign In Nabokov (And Pushkin), Victor Fet
Pushkin’s non-apocryphal anti-locust campaign is reflected in Nabokov’s unpublished sequel to The Gift.
Zoological Nomenclature And Kinbote’S Name Of God, 2017 Marshall University
Zoological Nomenclature And Kinbote’S Name Of God, Victor Fet
In Nabokov’s Pale Fire, Kinbote explains that the Name of God holds priority over Nature, etc. I show that the ‘priority principle’ here can be interpreted in the strict terms of zoological nomenclature.
Notes On Eryx, Omega, And Ata, 2017 Marshall University
Notes On Eryx, Omega, And Ata, Victor Fet
Observations on several Nabokov’s works (Pale Fire, Lolita) where geographic or zoological names provide sources for puns and hidden parallels.
Recognizing Challenges And Opportunities In The Quest To End Hunger, 2017 Texas A&M University School of Law
Recognizing Challenges And Opportunities In The Quest To End Hunger, Jennifer Williams Zwagerman
Texas A&M Law Review
As an attorney and professor that does not focus on intellectual property law, I was a bit apprehensive about providing a keynote address for a Symposium focusing on “Agriculture, Intellectual Property, and Feeding the World in the 21st Century.” As I thought about this topic, knowing that there were other speakers who would focus more on the IP issues and technical aspects of various topics, I kept coming back to the importance of technology as we worktowards the goal of feeding the world, and the many ways in which innovation plays a role in meeting that goal. It also brought ...
American Woodcock Migration Ecology At An Important Stopover, Cape May, New Jersey, 2017 University of Maine
American Woodcock Migration Ecology At An Important Stopover, Cape May, New Jersey, Brian B. Allen
Electronic Theses and Dissertations
Migration poses risks and energetic demands to individuals that may be greater than those experienced during non-migratory periods. Most migratory birds require stopover sites to rest and recuperate energy spent during migratory flights, and stopover locations can alleviate risks and provide supplemental energy en route to the animal’s end destination. An individual’s stopover duration is contingent first on energy acquisition that is constrained by resource availability, and secondarily on environmental conditions such as weather that may facilitate or constrain continued migration. From 2010 to 2013 I conducted a radio-telemetry study of a short-distance migrant, the American Woodcock (Scolopax ...
T-Time: A Data Repository Of T Cell And Calcium Release-Activated Calcium Channel Activation Imagery, 2017 Chapman University
T-Time: A Data Repository Of T Cell And Calcium Release-Activated Calcium Channel Activation Imagery, Cody Arbuckle, Milton L. Greenberg, Adrienne Bergh, Rene German, Nick Sirago, Erik J. Linstead
Mathematics, Physics, and Computer Science Faculty Articles and Research
BACKGROUND: A fundamental understanding of live-cell dynamics is necessary in order to advance scientific techniques and personalized medicine. For this understanding to be possible, image processing techniques, probes, tracking algorithms and many other methodologies must be improved. Currently there are no large open-source datasets containing live-cell imaging to act as a standard for the community. As a result, researchers cannot evaluate their methodologies on an independent benchmark or leverage such a dataset to formulate scientific questions.
FINDINGS: Here we present T-Time, the largest free and publicly available data set of T cell phase contrast imagery designed with the intention of ...
Effects Of Stocking Rate And Botanical Composition On The Physical Characteristics Of The Riparian Zones Of Pastures (A Two-Year Progress Report), Douglas Allen Bear, James R. Russell, Daniel G. Morrical, Mustafa Tufekcioglu, Thomas M. Isenhart, John L. Kovar
Thomas M. Isenhart
Grazing management practices that allow cattle to congregate near pasture streams may result in the loss of vegetative cover and promote accumulation of manure near the streams, increasing the risk of nonpoint source pollution of the stream. The objective of this project was to evaluate the effects of stocking rate of pastures and the botanical composition of the pastures’ riparian zone on the forage sward height and the proportions of bare and manure-covered ground along the banks of pasture streams.
Implementation Of Food Defense Best Practices In Northern U.S. School Nutrition Programs: A Case Study, Carol J. Klitzke, Catherine H. Strohbehn, Susan W. Arendt
Susan W. Arendt
One act of intentional contamination of school meals can quickly harm many children. Food defense guidelines for schools exist; yet previous research has found communication, utility security, and physical security practices are infrequently implemented. A multi-site case study approach obtained a 360-degree assessment of food defense practices in five school districts. Meal production and service were observed, a food defense checklist was completed, and key stakeholders were interviewed. Qualitative analysis of interviews revealed lack of awareness, lack of concern, conflicting priorities, and isolation of food service from other school operations impaired food defense implementation. School security measures protected children, but ...