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Molecular Biology Of A Surface-Exposed Protein Family Of Bartonella Bacilliformis, Hannah Fay 2017 University of Montana

Molecular Biology Of A Surface-Exposed Protein Family Of Bartonella Bacilliformis, Hannah Fay

Undergraduate Theses and Professional Papers

Bartonella bacilliformis is a gram negative alpha-proteobacterium native to the Andes of South America. Bartonella causes Carrion’s disease, a potentially life threatening disease transmitted by the sand fly. It has a mortality rate of 88% when untreated and 10% when treated. Diagnostics and control measures for the disease are underdeveloped and no vaccine is available. Recent outbreaks indicate that the range of the pathogen is increasing with nearly 1.7 million people in western South America at risk. Little is known about the epidemiology and pathogenesis of B. bacilliformis. Recent research done by UC San Diego found a paralogous ...


Effects Of Piscine Reovirus Infection On Innate Immune Signalling In Salmon, Mark Polinski 2016 Fisheries and Oceans Canada

Effects Of Piscine Reovirus Infection On Innate Immune Signalling In Salmon, Mark Polinski

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


First Evidence For A Vibrio Strain Pathogenic To Mytilus Edulis Altering Hemocyte Immune Capacities, YOSRA BEN CHEIKH 2016 University of le Havre

First Evidence For A Vibrio Strain Pathogenic To Mytilus Edulis Altering Hemocyte Immune Capacities, Yosra Ben Cheikh

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Channa Striatus Tnfr-1: Molecular Cloning, Characterization And Gene Expression, Rajesh Palanisamy 2016 SRM Institute of Science and Technology

Channa Striatus Tnfr-1: Molecular Cloning, Characterization And Gene Expression, Rajesh Palanisamy

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Understanding Viral Dsrna Production, Cell Entry And Use As An Antiviral Therapeutic In Rainbow Trout, Sarah J. Poynter, Amal Aloufi, Jeremy Weleff, Adam Soares, Stephanie J. DeWitte-Orr 2016 University of Waterloo

Understanding Viral Dsrna Production, Cell Entry And Use As An Antiviral Therapeutic In Rainbow Trout, Sarah J. Poynter, Amal Aloufi, Jeremy Weleff, Adam Soares, Stephanie J. Dewitte-Orr

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Fatty Acid Synthase And The Lipogenic Phenotype In Wssv-Infected Shrimp, Han-Ching Wang 2016 National Cheng Kung University

Fatty Acid Synthase And The Lipogenic Phenotype In Wssv-Infected Shrimp, Han-Ching Wang

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Lipid Metabolism During Wssv Infection In Shrimp, Cheng Cheng Shun 2016 The University of Maine

Lipid Metabolism During Wssv Infection In Shrimp, Cheng Cheng Shun

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Implication Of Biological And Synthetic Nanoparticles In Evolution And Development Of Antibiotic Resistance Relevant For Aquaculture, Petter Langlete 2016 University of Oslo

Implication Of Biological And Synthetic Nanoparticles In Evolution And Development Of Antibiotic Resistance Relevant For Aquaculture, Petter Langlete

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Expression Kinetics Of Interferon Stimulated Genes In Atlantic Salmon Head Kidney Cells (Ask) Nucleofected With Poly(I:C), Adriana Magalhaes Santos Andresen 19821, Tor Gjøen 2016 University of Oslo

Expression Kinetics Of Interferon Stimulated Genes In Atlantic Salmon Head Kidney Cells (Ask) Nucleofected With Poly(I:C), Adriana Magalhaes Santos Andresen 19821, Tor Gjøen

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


Biosynthesis And Roles Of Virulence Conferring Cell Wall Associated Dimycocerosate Esters In Mycobacterium Marinum, Poornima Mohandas 2016 Graduate Center, City University of New York

Biosynthesis And Roles Of Virulence Conferring Cell Wall Associated Dimycocerosate Esters In Mycobacterium Marinum, Poornima Mohandas

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

Mycobacterial species include a variety of obligate and opportunistic pathogens that cause several important diseases affecting mankind such as tuberculosis and leprosy. The most unique feature of these bacteria is their intricate cell wall that poses a permeability barrier to antibiotics and contributes to their pathogenicity and persistence within the host. The cell wall hosts several complex lipids such as dimycocerosate esters (DIMs), which are found in many clinically relevant pathogenic species of mycobacteria. DIMs have been implicated in the virulence of mycobacteria and play a major role in helping the bacteria evade host immune responses. It is therefore crucial ...


Mathematical Models Of Biofilm For Antimicrobial Persistence, Jia Zhao 2016 University of North Carolina at Chapel Hill

Mathematical Models Of Biofilm For Antimicrobial Persistence, Jia Zhao

Biology and Medicine Through Mathematics Conference

No abstract provided.


Needle In The Haystack: Combining Intravital Imaging And Mathematical Modeling To Understand How Vaccine-Induced T Cells Find Malaria-Infected Cells In Murine Livers, Vitaly V. Ganusov, Ian Cockburn, Reka Kelemen 2016 University of Tennessee

Needle In The Haystack: Combining Intravital Imaging And Mathematical Modeling To Understand How Vaccine-Induced T Cells Find Malaria-Infected Cells In Murine Livers, Vitaly V. Ganusov, Ian Cockburn, Reka Kelemen

Biology and Medicine Through Mathematics Conference

No abstract provided.


Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez 2016 Augustana College, Rock Island Illinois

Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez

Biology: Student Scholarship & Creative Works

ABSTRACT: The HIV-1 pandemic continues to thrive due to ineffective HIV-1 vaccines. Historically, the world’s most infectious diseases, such as polio and smallpox, have been eradicated or have come close to eradication due to the advent of effective vaccines. Highly active antiretroviral therapy is able to delay the onset of AIDS but can neither rid the body of HIV-1 proviral DNA nor prevent further transmission. A prophylactic vaccine that prevents the various mechanisms HIV-1 has to evade and attack our immune system is needed to end the HIV-1 pandemic. Recent advances in engineered nuclease systems, like the CRISPR/Cas9 ...


Water Quality And Fecal Coliform Levels In Georgia Oxbow Lakes Relative To Connectivity With The Savannah River, Carly B. Williams, John E. Weinstein, Claudia L. Rocha 2016 The Citadel, The Military College of South Carolina

Water Quality And Fecal Coliform Levels In Georgia Oxbow Lakes Relative To Connectivity With The Savannah River, Carly B. Williams, John E. Weinstein, Claudia L. Rocha

Georgia Journal of Science

The state of Georgia has many bodies of water that provide important wildlife habitats as well as recreational opportunities. The objective of the current study was to investigate water quality and fecal coliform levels in oxbow lakes relative to their connectivity to the Savannah River. For most water quality parameters, no differences were observed between the Savannah River and the oxbow lakes. However, pH and turbidity values were lower in the oxbow lakes (both connected and disconnected) relative to the Savannah River. Fecal coliform values between connected oxbow lakes and the Savannah River were similar to each other and significantly ...


Characterization Of A Mitochondrial Localizing Molluscum Contagiosum Virus Protein: Mc163r, Jesse Coutu 2016 Seton Hall University

Characterization Of A Mitochondrial Localizing Molluscum Contagiosum Virus Protein: Mc163r, Jesse Coutu

Seton Hall University Dissertations and Theses (ETDs)

Molluscum Contagiosum Virus (MCV) is an obligate human, tumorigenic poxvirus which causes benign skin neoplasms. Reduced inflammation during an MCV infection has been attributed to production of MCV immune evasion molecules (IEMs). IEMs antagonize host immune responses allowing MCV to evade the host immune system and reprogram the host cell for viral growth. MCV IEMs alter apoptosis (MC159, MC160), deregulate the cell cycle targeting retinoblastoma (MC007), and produce a chemokine homolog (MC148). Bioinformatics analysis identified MC163, as another potential host-interacting protein. Further analysis of MC163 resulted in the identification of a mitochondrial localization sequence, putative superoxide dismutase (SOD)-like Cu ...


Lignocellulose As Carbon Source Promotes Bacterial Synergism And Reduces Antagonism, Yijie Deng 2016 The University of Southern Mississippi

Lignocellulose As Carbon Source Promotes Bacterial Synergism And Reduces Antagonism, Yijie Deng

Dissertations

Lignocellulose decomposes slowly in nature because it consists of complex polymers resistant to enzymatic degradation by most organisms. Some bacteria are capable of producing cellulolytic enzymes but the way in which bacteria interact within a community to enhance degradation of the recalcitrant substrate is poorly understood. A better understanding of how bacterial interactions affect lignocellulose degradation would provide potential approaches to improve the efficiency of lignocellulose degradation for biofuel production.

To study whether bacterial interactions enhance lignocellulose degradation, I grew environmental bacterial isolates in mixed cultures and pure cultures. I found that bacterial synergism in mixed cultures was common in ...


Disease-Causing Fungi In Homes And Yards In The Midwestern United States, Dennis J. Baumgardner 2016 Aurora UW Medical Group, Aurora Health Care

Disease-Causing Fungi In Homes And Yards In The Midwestern United States, Dennis J. Baumgardner

Dennis J. Baumgardner. MD

A number of fungal pathogens that may result in a variety of human diseases are found in residential homes and yards. The growth of these microscopic fungi is often favored by particular characteristics of the dwelling and nearby outdoor environment. Evolved virulence factors or increased ability of specific fungi to grow in diverse, and sometimes harsh, microenvironments presented by the domestic environment may promote growth and pathogenesis. Infection may occur by inhalation or direct inoculation and include endemic fungi in addition to opportunistic or emerging species. Systemic or locally aggressive fungal infections are particularly likely and may be life-threatening in ...


Blastomyces: Why Be Dimorphic?, Dennis J. Baumgardner 2016 Aurora UW Medical Group, Aurora Health Care

Blastomyces: Why Be Dimorphic?, Dennis J. Baumgardner

Dennis J. Baumgardner. MD

In introducing the infectious disease focus for this edition of the Journal of Patient-Centered Research and Reviews, the author describes the unsolved mysteries surrounding the dimorphic fungus Blastomyces and the related pathogenesis of pulmonary blastomycosis.


Handwashing: A Study Of The History, Methods, And Psychology Surrounding Hand Hygiene, Daniel J. Remillard 2016 Liberty University

Handwashing: A Study Of The History, Methods, And Psychology Surrounding Hand Hygiene, Daniel J. Remillard

Senior Honors Theses

This paper covers three different areas concerning handwashing. First a review of the history of handwashing is done, going from ancient times to its introduction into modern medicine via Dr. Ignaz Semmelweis. This section gives a sobering reminder not to instantly reject data that comes in conflict with prevalent thought.

Then current medical knowledge about handwashing is examined, and the conclusion reached states that handwashing is best done with non-antibacterial soap.

Finally, a review of the psychology of handwashing shows that medical professionals often tend toward neglect if unwatched and unmotivated by an outside source. However, those suffering from obsessive ...


Altered Expression Of Cell Cycle And Apoptotic Proteins In Chronic Hepatitis C Virus Infection., Saira Sarfraz, Saeed Hamid, Anwar Ali Siddiqui, Snawar Hussain, Shahid Pervez, Graeme Alexander 2016 Aga Khan University

Altered Expression Of Cell Cycle And Apoptotic Proteins In Chronic Hepatitis C Virus Infection., Saira Sarfraz, Saeed Hamid, Anwar Ali Siddiqui, Snawar Hussain, Shahid Pervez, Graeme Alexander

Anwar Ali Siddiqui

Background: A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to further elaborate these disruptions by evaluating the expression of key cell cycle and apoptotic proteins in chronic HCV infection with particular reference to genotype 3. Archival liver biopsy specimens of chronic HCV-infection (n = 46) and normal histology (n = 5) were analyzed by immunohistochemistry using antibodies against proliferation marker Mcm-2, G1 phase marker Cyclin D1, S phase marker Cyclin A, cell cycle regulators p21 (CDK inhibitor) and p53 (tumor suppressor protein ...


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