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Pharmacology, Toxicology and Environmental Health Commons

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Environmental Res. Bernard Singleton 2016 .Pdf, Joy Semien 2016 Texas Southern University

Environmental Res. Bernard Singleton 2016 .Pdf, Joy Semien

Joy Semien

The Deepwater Horizon (DWH) oil spill in the Gulf of Mexico was the largest maritime oil spill in history
resulting in the accumulation of genotoxic substances in the air, soil, and water. This has potential far-
reaching health impacts on cleanup field workers and on the populations living in the contaminated
coastal areas. We have employed portable airborne particulate matter samplers (SKC Biosampler Im-
pinger) and a genetically engineered bacterial reporter system (umu-ChromoTest from EBPI) to de-
termine levels of genotoxicity of air samples collected from highly contaminated areas of coastal
Louisiana including Grand Isle, Port Fourchon, and Elmer's ...


Ex Vivo Immune Responses In Freshwater Fish Leucocytes Exposed To Environmental Serotypes Of Lipopolysaccharides, Hakim SAMAI 2016 Université Reims Champagne-Ardenne, UMR-I 02 SEBIO

Ex Vivo Immune Responses In Freshwater Fish Leucocytes Exposed To Environmental Serotypes Of Lipopolysaccharides, Hakim Samai

2nd International Conference of Fish & Shellfish Immunology

No abstract provided.


The 2014 National Community Summit On Green Infrastructure: Summary Report, Stuart Mendel, Justin Glanville, Julie Quinn 2016 Cleveland State University

The 2014 National Community Summit On Green Infrastructure: Summary Report, Stuart Mendel, Justin Glanville, Julie Quinn

Stuart C Mendel

This report presents key points from each dialogue session, as well as overall themes from the Summit as a whole. These key points and themes were synthesized by dialogue facilitators and representatives from CSU, NEORSD and EPA. In addition, this report presents narrative versions of the lead presentations for each session. These are meant to serve as case studies of best practices to address each session topic.


Investigations Of The Effects Of Different Ventilation Structures On Physiologically Based Pharmacokinetic Modeling (Pbpk) Simulations, Karen A. Yokley 2016 Elon University

Investigations Of The Effects Of Different Ventilation Structures On Physiologically Based Pharmacokinetic Modeling (Pbpk) Simulations, Karen A. Yokley

Biology and Medicine Through Mathematics Conference

No abstract provided.


Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez 2016 Augustana College, Rock Island Illinois

Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez

Biology: Student Scholarship & Creative Works

ABSTRACT: The HIV-1 pandemic continues to thrive due to ineffective HIV-1 vaccines. Historically, the world’s most infectious diseases, such as polio and smallpox, have been eradicated or have come close to eradication due to the advent of effective vaccines. Highly active antiretroviral therapy is able to delay the onset of AIDS but can neither rid the body of HIV-1 proviral DNA nor prevent further transmission. A prophylactic vaccine that prevents the various mechanisms HIV-1 has to evade and attack our immune system is needed to end the HIV-1 pandemic. Recent advances in engineered nuclease systems, like the CRISPR/Cas9 ...


Water Quality And Fecal Coliform Levels In Georgia Oxbow Lakes Relative To Connectivity With The Savannah River, Carly B. Williams, John E. Weinstein, Claudia L. Rocha 2016 The Citadel, The Military College of South Carolina

Water Quality And Fecal Coliform Levels In Georgia Oxbow Lakes Relative To Connectivity With The Savannah River, Carly B. Williams, John E. Weinstein, Claudia L. Rocha

Georgia Journal of Science

The state of Georgia has many bodies of water that provide important wildlife habitats as well as recreational opportunities. The objective of the current study was to investigate water quality and fecal coliform levels in oxbow lakes relative to their connectivity to the Savannah River. For most water quality parameters, no differences were observed between the Savannah River and the oxbow lakes. However, pH and turbidity values were lower in the oxbow lakes (both connected and disconnected) relative to the Savannah River. Fecal coliform values between connected oxbow lakes and the Savannah River were similar to each other and significantly ...


The Effects Of The Environmental Estrogens Cadmium And Arsenite On Phosphorylation Of Erk1/2 Via Gpr30 In Human Lung Adenocarcinoma Cells, Katarzyna Krauss 2016 Bellarmine University

The Effects Of The Environmental Estrogens Cadmium And Arsenite On Phosphorylation Of Erk1/2 Via Gpr30 In Human Lung Adenocarcinoma Cells, Katarzyna Krauss

Undergraduate Theses

Nanomolar concentrations of both cadmium and arsenite, two environmental estrogens present in cigarette smoke, have been documented in rapidly phosphorylating ERK1/2, a type of MAPK, in the human non-small cell lung cancer (NSCLC) line NHI-1793 in a manner similar to that of estrogen. Pretreatment of cells with a general, nonspecific estrogen receptor antagonist reduced the levels of phosphorylated MAPK, indicating that this phosphorylation event is achieved through use of an estrogen signaling pathway. The specific estrogen receptor involved in this process, however, is currently unknown. To determine whether GPR30, one of the three types of estrogen receptors, is necessary ...


What You Ignore At Work May Harm You: The Effects Of Light, Design, And Nature, Shelby L. Beutel 2016 Butler University

What You Ignore At Work May Harm You: The Effects Of Light, Design, And Nature, Shelby L. Beutel

BU Well

This paper looks into the effects of light, design, and nature on employees by incorporating environmental health and environmental design research into useful suggestions for the employee and the employer. The “fit” between a user and their work space has been elaborated on in recent years, and it has been shown that insufficient lighting can cause poor fit and consequential draining of energy and productivity. In the healthcare setting, medication errors have been linked to the amount of lighting within a hospital and to the variable amount of daylight throughout the year. While there is not a quick and easy ...


Impacts From The Use Of Antibiotics In Livestock: Methods Of Transmission Of Antibiotic Resistance From Livestock To Humans, Kristin M. Walden 2016 Augustana College, Rock Island Illinois

Impacts From The Use Of Antibiotics In Livestock: Methods Of Transmission Of Antibiotic Resistance From Livestock To Humans, Kristin M. Walden

Biology: Student Scholarship & Creative Works

Antibiotic use in livestock production has been around since the 1950s. Antibiotic feed is used in livestock and other meat producing animals for three reasons: illness prevention, illness treatment, and growth promotion. Unfortunately, since the time that antibiotics were first invented, antibiotic resistant bacteria have become a threat to public health. There are many studies showing methods of transmission of antibiotic resistance from livestock to humans. Antibiotic resistance can spread from livestock to soil, water, insects, and food, which ultimately comes into contact with humans. A proposed study to measure antibiotic resistance when eliminating antibiotic feed will provide a hypothesis ...


Pharmaceuticals And Industrial Products In Crops: Economic Prospects And Impacts On Agriculture, Gregory D. Graff, GianCarlo Moschini 2016 University of California, Berkeley

Pharmaceuticals And Industrial Products In Crops: Economic Prospects And Impacts On Agriculture, Gregory D. Graff, Giancarlo Moschini

Giancarlo Moschini

That biotechnology has brought changes to agriculture in a very short time is, by now, obvious. For the 2004 harvest, for example, it is estimated that 85 percent of U.S. soybean production and 45 percent of U.S. corn production will come from genetically modified (GM) varieties (89 percent and 54 percent, respectively, in Iowa). While the agricultural sector is still dealing with problematic trade effects caused by less-than-enthusiastic consumer acceptance and restrictive regulations overseas, the biotech industry is actively pursuing an array of R&D efforts that could make the current adoption of GM crops just the prototypical ...


The Ecorep Program At The University Of South Carolina: How To Engage Students In On-Campus Environmental Activities, Veronica Dorothy Farrell 2016 University of South Carolina - Columbia

The Ecorep Program At The University Of South Carolina: How To Engage Students In On-Campus Environmental Activities, Veronica Dorothy Farrell

Theses and Dissertations

This senior thesis focused on determining how much the undergraduate student population is aware about current environmental problems, their impression of them, and how they act accordingly. In addition, through completion of this thesis I hoped to understand what motivates students to participate in events on campus in order to more effectively increase awareness or sustainable behaviors. Specific interest was placed on the students at the University of South Carolina. I oriented this research for one environmental organization at the University of South Carolina in particular, known as EcoReps. EcoReps are peer leaders that strive to educate students about environmental ...


Plastic Pollution And The Global Throwaway Culture: Environmental Injustices Of Single-Use Plastic, Kristin L. McDermott 2016 Salve Regina University

Plastic Pollution And The Global Throwaway Culture: Environmental Injustices Of Single-Use Plastic, Kristin L. Mcdermott

ENV 434 Environmental Justice

The global throwaway culture has created a cross-ecosystem plastic pollution injustice. The first to suffer this injustice will be the most vulnerable. Our oceans have become our dumpsters. The throwaway culture has created a disrespect of material goods that has turned the earth’s resources into rubbish after a single use. Eighty percent of the yearly 8 million tons of plastic that enter the ocean is single use plastic, such as plastic bottles, plastic shopping bags, or cigarette lighters.[1] Plastic has destroyed ecosystems, robbing impoverished communities of natural resources and of a healthy and safe living environment. First to ...


Effect Of Bisphenol-A On Neurodevelopment In Drosophila Melanogaster Larvae, Alexandra M. Streifel 2016 College of Saint Benedict/Saint John's University

Effect Of Bisphenol-A On Neurodevelopment In Drosophila Melanogaster Larvae, Alexandra M. Streifel

All College Thesis Program

This paper examines the effects of the chemical preservative bisphenol-A on the developing nervous systems of Drosophila melanogaster, or fruit fly, larvae. This study examines the effects of bisphenol-A using both behavioral as well as morphological paradigms. It was determined that bisphenol-A significantly increased the amount of time larvae spent in seeking behavior, the number of peristaltic contractions, and the distance traveled in a linear fashion. In the morphological analysis, indications of increased dendritic area in experimental larvae existed, but there was not enough data to determine significance. For future research, it is recommended that more data be gathered to ...


Isolation And Characterization Of Microbial Communities From Hydraulic Fracturing Fluids, Sheridan S. Brewer 6284984 2016 University of Tennessee, Knoxville

Isolation And Characterization Of Microbial Communities From Hydraulic Fracturing Fluids, Sheridan S. Brewer 6284984

University of Tennessee Honors Thesis Projects

No abstract provided.


Comparing The Quantitation Of Opiates From Possible Drug Overdose Cases Using Results Of Blood Analysis And Liver Analysis, Lee Ann Garozzo 2016 State University of New York Buffalo State

Comparing The Quantitation Of Opiates From Possible Drug Overdose Cases Using Results Of Blood Analysis And Liver Analysis, Lee Ann Garozzo

Forensic Science Theses

Currently the quantitation of opiates at the Erie County Medical Examiner’s Office Toxicology Laboratory is conducted through whole blood analysis. The objective of this thesis project was to determine if the analysis of opiates could be conducted through liver analysis, and if the analysis of opiates would provide a more accurate quantitation compared to the blood analysis. The quantitation of opiates was conducted from the livers of sixty-four possible overdose cases that were brought into the Erie County Medical Examiner’s Office between 2013 and 2015. Results showed that the opiate drugs could successfully be quantitated using the liver ...


The Emergence Of Systematic Review In Toxicology, Martin L. Stephens, Kellyn Betts, Nancy Beck, Vincent Cogliano, Kay Dickersin, George Gray, +8 additional authors 2016 George Washington University

The Emergence Of Systematic Review In Toxicology, Martin L. Stephens, Kellyn Betts, Nancy Beck, Vincent Cogliano, Kay Dickersin, George Gray, +8 Additional Authors

Environmental and Occupational Health Faculty Publications

The Evidence-based Toxicology Collaboration hosted a workshop on “The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology,” on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts ...


The Significance Of Sound & The Dynamic Of Music Therapy, Christina E. Borchers 2016 Wright State University - Main Campus

The Significance Of Sound & The Dynamic Of Music Therapy, Christina E. Borchers

Christina Borchers

How does sound impact your brain? And how can we use music to gain wholeness in ways that pharmaceutical medicine is limited?

In this fusion between music and science, pianist turned pharmacology and toxicology scientist, Christina Borchers, guides us through the powerful intersection of the two fields. The body is naturally capable of self-regulation and healing. Music therapy activates our own pathways to begin working. Drawing upon breakthrough studies in music therapy along with music history, Borchers exposes:

• How sound is the most dominant of the senses
• That there are two forms of music: the music of playing and the ...


Ecological Risks Of The Conventional Insecticide/Fungicide Seed Treatment Mixture Of Thiamethoxam And Mefenoxam In Soybean On Beneficial Insects, Carolina Camargo 2016 University of Nebraska-Lincoln

Ecological Risks Of The Conventional Insecticide/Fungicide Seed Treatment Mixture Of Thiamethoxam And Mefenoxam In Soybean On Beneficial Insects, Carolina Camargo

Dissertations and Student Research in Entomology

The impact of neonicotinoid seed treatments on beneficial insects has been a controversial topic during the last years. While neonicotinoids are usually used as mixtures with systemic fungicides, few studies have examined the impact of the mixtures on beneficial insects. Pesticide mixtures can have synergistic, additive, or antagonistic effects on the toxicity of neonicotinoids on non-target species.

Thiamethoxam with mefenoxam is the most used neonicotinoid insecticide/fungicide mixture applied to soybean. Based on the systemic nature of thiamethoxam and mefenoxam, residues of this insecticide/fungicide mixture can be present in soybean vegetative and floral tissue with potential impacts to beneficial ...


Implementing A Community-Based Social Marketing Project To Improve Agricultural Worker Health, Joan D. Flocks, Leslie Clarke, Stan Albrecht, Carol Bryant, Paul Monaghan, Holly Baker 2016 University of Florida Levin College of Law

Implementing A Community-Based Social Marketing Project To Improve Agricultural Worker Health, Joan D. Flocks, Leslie Clarke, Stan Albrecht, Carol Bryant, Paul Monaghan, Holly Baker

Joan D. Flocks

The Together for Agricultural Safety project is a community-based social marketing project working to reduce the adverse health effects of pesticide exposure among fernery and nursery workers in Florida. In 3 years, the collaboration between university and community researchers has embodied many of the principles of community-based research while completing multiple stages of formative data collection required for a social marketing project. This hybrid approach to developing a health intervention for a minority community has been successful in its early stages because the community partners are organized, empowered, and motivated to execute research activities with the assistance of academic partners ...


Pesticide Policy And Farmworker Health, Joan D. Flocks 2016 University of Florida Levin College of Law

Pesticide Policy And Farmworker Health, Joan D. Flocks

Joan D. Flocks

Although data on the carcinogenicity of agricultural pesticides are still being generated and are thus incomplete, research such as the Agricultural Health Study indicates that populations with increased, regular exposure to pesticides have high rates of a variety of cancers (National Institutes of Health & Environmental Protection Agency 2008). Policies that regulate toxins such as pesticides are envisioned by the public to be empirical and objective, but toxins are socially produced and their regulation is just as often based on political and economic factors as it is on science (Luke 2000). This does not bode well for farm- workers who are ...


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