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An Analysis Of Mayo Clinic Search Query Logs For Cardiovascular Diseases, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak 2014 Wright State University

An Analysis Of Mayo Clinic Search Query Logs For Cardiovascular Diseases, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak

Kno.e.sis Publications

Increasingly, individuals are taking active participation in learning and managing their health by leveraging online resources. Understanding online health information searching behavior can help us to study what health topics users search for and how search queries are formulated. In this work, we analyzed 10 million cardiovascular diseases (CVD) related search queries from MayoClinic.com. We performed semantic analysis on the queries using UMLS MetaMap and analyzed structural and textual properties as well as linguistic characteristics of the queries.


Online Information Searching For Cardiovascular Diseases: An Analysis Of Mayo Clinic Search Query Logs, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak 2014 Wright State University

Online Information Searching For Cardiovascular Diseases: An Analysis Of Mayo Clinic Search Query Logs, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak

Kno.e.sis Publications

Since the early 2000’s, Internet usage for health information searching has increased significantly. Studying search queries can help us to understand users “information need” and how do they formulate search queries (“expression of information need”). Although cardiovascular diseases (CVD) affect a large percentage of the population, few studies have investigated how and what users search for CVD. We address this knowledge gap in the community by analyzing a large corpus of 10 million CVD related search queries from MayoClinic.com. Using UMLS MetaMap and UMLS semantic types/concepts, we developed a rule-based approach to categorize the queries into 14 ...


Hundreds Of Scn-Resistant Soybean Varieties Available For 2014, Gregory L. Tylka 2014 Iowa State University

Hundreds Of Scn-Resistant Soybean Varieties Available For 2014, Gregory L. Tylka

Integrated Crop Management News

The soybean cyst nematode (SCN) is a serious yield-reducing pathogen of soybeans. It is present in many fields throughout the Midwest, wherever soybeans are grown.

To produce profitable soybean yields in fields infested with SCN, farmers should grow SCN-resistant soybean varieties. SCN-resistant soybeans can produce high yields while keeping SCN population densities from increasing.


Dahp Oxime: A Transition State Mimic Inhibitor Of Dahp Synthase, Naresh Balachandran 2014 McMaster University

Dahp Oxime: A Transition State Mimic Inhibitor Of Dahp Synthase, Naresh Balachandran

Open Access Dissertations and Theses

The rise of bacterial infections and increase of antibiotic resistant bacteria has become a major problem in the treatment of bacterial infections. The use and overuse of antibiotics, and the inherent ability of bacteria to adapt to their environment, have lead to the emergence of strains that are resistant to all antibiotics. Ideally, new targets for antibacterial drug therapy would be essential to the virulence of most or all bacteria. That is, antibiotics exploiting these targets would have broad spectrum activity. 3-Deoxy-D-arabinoheptulosonate-7- phosphate (DAHP) synthase could be such a target. This enzyme catalyzes the condensation of erythrose 4-phosphate (E4P) and ...


A Characterization Of The Dynamic Interaction Between The Pro-Apoptotic Protein Bid And The Mitochondrial Outer Membrane, Aisha Shamas-Din Ms. 2014 McMaster University

A Characterization Of The Dynamic Interaction Between The Pro-Apoptotic Protein Bid And The Mitochondrial Outer Membrane, Aisha Shamas-Din Ms.

Open Access Dissertations and Theses

Bcl-2 family of proteins regulate apoptosis at the level of the mitochondrial outer membrane (MOM) through both protein-protein and protein-membrane interactions. While the role of the membrane as the “locus of action” has been recognized, the detailed molecular mechanisms and the consequences of the interactions of Bcl-2 family members with the membrane are yet to be fully understood. The findings presented here focus on the dynamic interactions of Bcl-2 proteins, most notably tBid with the MOM, and their functional significance on mitochondrial outer membrane permeabilization. We show that the activation of tBid is a multi-step process that is regulated by ...


Investigation Of Competence Heterogeneity In Streptococcus Milleri Group Clinical Isolates, Anne-Marie G. Lacroix 2014 McMaster University

Investigation Of Competence Heterogeneity In Streptococcus Milleri Group Clinical Isolates, Anne-Marie G. Lacroix

Open Access Dissertations and Theses

The Streptococcus Milleri/Anginosus group (SMG) includes Streptococcus anginosus, Streptococcus constellatus and Streptococcus intermedius. The SMG is found in healthy individuals but these bacteria are most known clinically for being associated with invasive disease and more recently, airway infections including cystic fibrosis (CF). The SMG like many other streptococci are naturally competent, being able to actively bind, uptake and integrate extracellular DNA. Competence regulation involves a competence-stimulating peptide (CSP) derived from the ComC precursor and a two- component signaling system (a histidine kinase ComD and its response regulator ComE). In this study, I examined the distribution of CSP/ComD sequences ...


The Centennial Of The Smith-Lever Act And Aquaculture Extension, Michael A. Rice 2014 University of Rhode Island

The Centennial Of The Smith-Lever Act And Aquaculture Extension, Michael A. Rice

Michael A Rice

May 8, 2014 marked the centennial of the landmark Smith-Lever Act in the United States that created the Cooperative Extension service at Land Grant Universities nationwide. Major contributors to the 1914 Act were Seaman A. Knapp and Kenyon L. Butterfield. A half century later the Sea Grant College Program was proposed by Athelstan F. Spilhaus expanding Extension programming to the sea. Together these two programs have been a major force in promoting the growth of the aquaculture industry in America.


Silence Is The Loudest Sound, Emma Christian 2014 The University of Maine

Silence Is The Loudest Sound, Emma Christian

Honors College

Rhinoceros poaching is an act of killing a rhinoceros in order to take its horn, which is then used for human consumption or for cultural traditions. Both the Asian and the African rhinoceros are targets because of the demand from China, Vietnam, Yemen, and other countries around the world. Traditional Chinese Medicine practice is the main demand for rhinoceros horn and this demand in rhinoceros horn has caused an increase in the black market. Conservation of the rhinoceros is decreasing primarily because the price of rhinoceros horn is more than double the average household income in South Africa, thus making ...


Mindful Eating: Trait And State Mindfulness Predict Healthier Eating Behavior, Christian H. Jordan, Wan Wang, Linda R. Donatoni '10, Brian P. Meier 2014 Gettysburg College

Mindful Eating: Trait And State Mindfulness Predict Healthier Eating Behavior, Christian H. Jordan, Wan Wang, Linda R. Donatoni '10, Brian P. Meier

Psychology Faculty Publications

Obesity and excess weight are significant societal problems. Mindfulness may encourage healthier weight and eating habits. Across four studies, we found a positive relation between mindfulness and healthier eating. Trait mindfulness was associated with less impulsive eating, reduced calorie consumption, and healthier snack choices. In addition, we found a causal effect of mindfulness on healthier eating. An experimental manipulation of state mindfulness led participants to consume fewer calories in a spontaneous eating task. We also found preliminary evidence that mindfulness affects eating behavior by encouraging attitudinal preferences for healthier foods. Taken together, these results provide strong evidence that mindfulness encourages ...


Diatom Flora In Subterranean Ecosystems: A Review, Elisa Falasco, Luc Ector, Marco Isaia, Carlos E. Wetzel, Lucien Hoffmann, Francesca Bona 2014 University of South Florida

Diatom Flora In Subterranean Ecosystems: A Review, Elisa Falasco, Luc Ector, Marco Isaia, Carlos E. Wetzel, Lucien Hoffmann, Francesca Bona

International Journal of Speleology

In scarcity of light and primary producers, subterranean ecosystems are generally extremely oligotrophic habitats, receiving poor supplies of degradable organic matter from the surface. Human direct impacts on cave ecosystems mainly derive from intensive tourism and recreational caving, causing important alterations to the whole subterranean environment. In particular, artificial lighting systems in show caves support the growth of autotrophic organisms (the so-called lampenflora), mainly composed of cyanobacteria, diatoms, chlorophytes, mosses and ferns producing exocellular polymeric substances (EPSs) made of polysaccharides, proteins, lipids and nucleic acids. This anionic EPSs matrix mediates to the intercellular communications and participates to the chemical exchanges ...


Niche Differentiation In Meta Bourneti And M. Menardi (Araneae, Tetragnathidae) With Notes On The Life History, Stefano Mammola, Marco Isaia 2014 University of South Florida

Niche Differentiation In Meta Bourneti And M. Menardi (Araneae, Tetragnathidae) With Notes On The Life History, Stefano Mammola, Marco Isaia

International Journal of Speleology

Meta menardi and M. bourneti are two species of spiders inhabiting caves and other subterranean habitats. The occurrence of both species within the same cave has never been proved convincingly and several authors hypothesized a complete niche differentiation mainly based on microclimatic conditions.In order to study the apparent niche differentiation of the two species, we studied several populations of M. menardi and M. bourneti occurring in six caves in the Western Italian Alps (NW Italy). A series of squared plots were monitored monthly from March 2012 to February 2013. At each survey, we counted individuals and we collected the ...


Effect Of Recent Historical Events On Migration And Isonymic Stratification Among The Rama Amerindians From Nicaragua, Norberto F. Baldi 2014 Wayne State University

Effect Of Recent Historical Events On Migration And Isonymic Stratification Among The Rama Amerindians From Nicaragua, Norberto F. Baldi

Human Biology Open Access Pre-Prints

The Rama Amerindians from southern Nicaragua are one of few indigenous populations inhabiting the east coast and lowlands of southern Central America. Early 18th century ethnohistorical accounts depicted the Rama as a mobile hunter-gatherer and horticulturalists group dispersed in household units along southern Nicaraguan rivers. However, during the 19th and 20th centuries, Rama settlement patterns changed to aggregated communities due to increased competition for local resources resulting from non-indigenous immigration. This study’s objective was to discern the degree of relatedness between and within subdivisions of seven of these communities based on patterns of surname variation and genealogical data. We ...


Health Risks Caused By Wireless Technologies, DurreeShahwar ZafarAhmed, Qurrat-ul-Ain ZafarAhmed 2014 Minnesota State University, Mankato

Health Risks Caused By Wireless Technologies, Durreeshahwar Zafarahmed, Qurrat-Ul-Ain Zafarahmed

Journal of Undergraduate Research at Minnesota State University, Mankato

There are many health issues related to the use of cellular phones, wireless local area networks, and other devices that emit electromagnetic radiation (EMR). Some of these systems have become a part of our daily lives and many of us are in direct or indirect contact for extended period of times with these devices. However, the general public is unaware of the health risks associated with the use of these devices. Our research covers studies done by individuals as well as organizations on the harmful effects on the health of people from these devices and their claims. We also present ...


Chromosome Counts For Packera Paupercula Variety Gypsophila, Chad Larson 2014 Minnesota State University, Mankato

Chromosome Counts For Packera Paupercula Variety Gypsophila, Chad Larson

Journal of Undergraduate Research at Minnesota State University, Mankato

New plant species develop when diploid plants (having two sets of chromosomes) spontaneously double their chromosomes and the resulting tetraploids (having four sets of chromosomes) are no longer able to back cross to diploid members of the population. The North American plant species Packera paupercula (balsam-leafed ragwort), is widespread and morphologically diverse. An isolated group of populations from the chalky soils of west-central Alabama was recently named Packera paupercula variety gypsophila (the chalk-loving balsam ragwort). The variety’s large diameter pollen grains suggest it may be tetraploid. This project attempts the first chromosome count for the variety by examining cells ...


Nisin Resistance Of Bacillus Cerus: Preparation Of Nisin, Peter Weber 2014 Minnesota State University, Mankato

Nisin Resistance Of Bacillus Cerus: Preparation Of Nisin, Peter Weber

Journal of Undergraduate Research at Minnesota State University, Mankato

Nisin is a peptide that is made by the bacterium Lactococcus lactis. Nisin is a small molecule that kills gram positive bacteria by binding to their membrane and by disrupting the proton motive force. When food is processed it is heated to kill bacteria, but some bacteria still survive. Adding nisin to the food provides a second barrier for the growth of the bacteria. Purified nisin has become quite expensive in the current marketplace. Therefore this study is directed at producing nisin and purifying it. L. lactis was grown in five different media (BHI, BHI + 1% glucose, BHI + 1% sucrose ...


The Innate Immune Response In Eisenia Fetida To Microbial Challenges, Aaron Schindler 2014 Minnesota State University, Mankato

The Innate Immune Response In Eisenia Fetida To Microbial Challenges, Aaron Schindler

Journal of Undergraduate Research at Minnesota State University, Mankato

The common earthworm, Eisenia fetida, exhibits a rudimentary immune system. The earthworm needs cellular and chemical responses against a constant microbial exposure from its natural environment. Some cellular and chemical responses are found in the coelomic fluid and have been shown to demonstrate anti-microbial characteristics. This project uses microscopy and modified staining techniques to differentiate and categorize the cellular components found in the coelomic fluid. Following a microbial challenge by Klebsiella pneumoniae, an inflammatory response was initiated. Six groups of earthworms were injected with 0.05 ml of 1.0 x 106 cfu /ml K. pneumoniae on day one and ...


Comparison Of Sequence Alignment Algorithms, Tejas Gandhi 2014 Minnesota State University, Mankato

Comparison Of Sequence Alignment Algorithms, Tejas Gandhi

Journal of Undergraduate Research at Minnesota State University, Mankato

The fact that biological sequences can be represented as strings belonging to a finite alphabet (A, C, G, and T for DNA) plays an important role in connecting biology to computer science. String representation allows researchers to apply various string comparison techniques available in computer science. As a result, various applications have been developed that facilitate the task of sequence alignment. The problem of finding sequence alignments consists of finding the best match between two biological sequences. A best match can infer an evolutionary relationship and functional similarity. However, there is a lack of research on how reliable and efficient ...


Critical Legal Studies, Daniel Fernando Gomez Tamayo 2014 SelectedWorks

Critical Legal Studies, Daniel Fernando Gomez Tamayo

Daniel Fernando Gomez Tamayo

Legal system, personal reading the Hart vs Dworkin, interdisciplinary research, the presidencialism- vs- parliamentarism, constitutionalism, (social rule of law). Fundamental rights of children. Contributions of science to the new concept of dignity (Katherine S. Pollard and Howard Gardner) Special People. Legal and international rules for the interpretation of human rights. American Canon Law.


Search For The Causative Organism Of Waterfowl Deaths At Lake Onalaska, Derek Skillings 2014 Minnesota State University, Mankato

Search For The Causative Organism Of Waterfowl Deaths At Lake Onalaska, Derek Skillings

Journal of Undergraduate Research at Minnesota State University, Mankato

American coots (Fulica americana) and diving ducks, including lesser scaup (Aythya affinis) and ring-necked ducks (Aythya collaris) have been dying in significant numbers on Lake Onalaska since 2001. Bird mortality is being attributed to parasitic infections from two intestinal trematodes, Cyathocotyle bushiensis and Sphaeridiotrema globulus. The birds begin dying in as little as two weeks of landing at this lake. Rapid mortality is not typically associated with trematode parasitism. Assuming these birds acquired their infections at Lake Onalaska, leads to the conclusion that our current understanding of the disease in this parasite-host system is lacking. Neorickettsiales are a group of ...


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