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Hybridization Kinetics Of Four-Way Junctions Localized On A Dna Scaffold, Katherine N. Taylor 2024 University of Central Florida

Hybridization Kinetics Of Four-Way Junctions Localized On A Dna Scaffold, Katherine N. Taylor

Honors Undergraduate Theses

DNA computing is an ever-growing field with scientists trying to design structures that optimize logic gate communication to develop fast, biologically compatible, computational structures. We hypothesize that by using the principles of DNA computing, it is possible to design a DNA tile capable of studying localized DNA hybridization that can differentiate between oligonucleotides of different structural conformations. This includes synthetically manipulating DNA into a nanostructure that can perform Boolean logic functions to calculate the different rates of hybridization. To test our hypothesis, we designed a DNA Tile that incorporated a 4WJ using YES logic. Linear and hairpin single-stranded (ss) DNA …


A Tool To Automate Neuropathological Assessment In Huntington Disease Mouse Models, Samuel A. Moldenhauer 2024 University of Central Florida

A Tool To Automate Neuropathological Assessment In Huntington Disease Mouse Models, Samuel A. Moldenhauer

Honors Undergraduate Theses

As our life expectancy continues to rise, so does the prevalence of neurodegenerative diseases, such as Huntington disease (HD). Neurodegeneration leads to progressive regional brain atrophy, typically initiating prior to symptom onset. With the advancements of medical treatments designed to target neurodegeneration, researchers measure their impact on atrophy in animal models to assess their effectiveness. This is important because treatments designed to combat neuropathology are more likely to modify the disease itself, per contra to treatments designed to mask or treat symptoms. One method of brain region size quantification is magnetic resonance imaging (MRI), which while accurate, is prohibitively expensive. …


Technological Advancements In Brunei’S Local Agriculture And Fisheries Companies: An Exploratory Study Based On Field Observations, Muhammad Firdaus Mujibuddin Syah Mustafa, Navaranjan Namasivayam, Hong Shyang Pei, Fatnin Farhanah Alihan, Amni Sahilah Sahrullamzah, Khairina Umairah Takiyaudin 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Gadong, BA1410, Bandar Seri Begawan, Brunei Darussalam

Technological Advancements In Brunei’S Local Agriculture And Fisheries Companies: An Exploratory Study Based On Field Observations, Muhammad Firdaus Mujibuddin Syah Mustafa, Navaranjan Namasivayam, Hong Shyang Pei, Fatnin Farhanah Alihan, Amni Sahilah Sahrullamzah, Khairina Umairah Takiyaudin

ASEAN Journal on Science and Technology for Development

This exploratory study, through seven field observations and interviews, investigates the technological advancements transforming Brunei's agricultural landscape in pursuit of local production augmentation and self-sufficiency. It confronts challenges with emerging technologies like aquaponics, hydroponics, fertigation systems, closed-house poultry systems, and UV lighting, which hold promise for enhanced farming practices. The research provides a comprehensive assessment of current practices, including livestock management advancements, underscoring their potential to boost productivity, optimize resource use, and promote sustainable agriculture. Furthermore, it discusses the broader implications for industry standards, job employability, and alignment with Brunei's Vision 2035. The findings contribute invaluable insights, advocating for strategic …


Exploring The Impact Of Vented Packaging Configurations On Airflow Patterns And Cooling Consistency For Muskmelons In A Cold Storage Environment, Nur Wafidah Roslan, Namasivayam Navaranjan, Zohrah Sulaiman, Naseem Uddin 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Exploring The Impact Of Vented Packaging Configurations On Airflow Patterns And Cooling Consistency For Muskmelons In A Cold Storage Environment, Nur Wafidah Roslan, Namasivayam Navaranjan, Zohrah Sulaiman, Naseem Uddin

ASEAN Journal on Science and Technology for Development

The cooling effect of different vented packaging designs was investigated for packed muskmelons fruits in a commercial cold storage condition. Computational fluid dynamics (CFD) simulation and experiments were used. The airflow pattern, heat transfer and temperature profiles were predicted from simulation and analysed. The CFD results reveal an uneven and low efficient airflow distribution inside a commercially used vented packaging (Box A). This resulted slow cooling of the fruits in Box A. Two newly designed packaging (Box B and Box C) showed better airflow distribution around the fruits and cooled them faster than Box A. The design of Box C …


Physicochemical Characterization Of Edible Insect Oils: Insights Into Fatty Acid Composition, Thermal Behavior And Quality Parameters, Eng-Tong Phuah, Yee-Ying Lee, Teck-Kim Tang, Guanghui Li, Shyang-Pei Hong, Syazana Abdullah Lim 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Physicochemical Characterization Of Edible Insect Oils: Insights Into Fatty Acid Composition, Thermal Behavior And Quality Parameters, Eng-Tong Phuah, Yee-Ying Lee, Teck-Kim Tang, Guanghui Li, Shyang-Pei Hong, Syazana Abdullah Lim

ASEAN Journal on Science and Technology for Development

Edible insects are emerging as a sustainable food source due to their high nutritional value. This study employed the three-phase partitioning (TPP) method to extract oils from sago worm (Rhynchophorus ferrugineus), superworm (Zophobas morio), and cricket (Acheta domesticus). The study evaluated and compared the physicochemical properties of these insect oils, including iodine value (IV), peroxide value (PV), p-anisidine value (p-AV), acid value (AV), refractive index (RI), thermal behavior, and fatty acid compositions. Results revealed that the sago worm exhibited the highest oil yield (47.8 ± 2.2%) compared to the superworm (23.8 ± 1.4%) and cricket (6.4 ± 0.6%). Cricket oil …


Recent Advance In Biodegradable Packaging From Banana Plant Feedstock: A Comprehensive Review, M. Atiq Juani, Namasivayam Navaranjan 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Recent Advance In Biodegradable Packaging From Banana Plant Feedstock: A Comprehensive Review, M. Atiq Juani, Namasivayam Navaranjan

ASEAN Journal on Science and Technology for Development

This review focuses on recent advances in biodegradable packaging derived from banana plant waste, highlighting its pivotal role in addressing environmental concerns linked to conventional packaging materials. The shift toward sustainable packaging stems from the urgent need to combat plastic pollution, reduce reliance on non-renewable resources, and foster sustainability in the food industry. Banana plants, known for generating significant organic waste during cultivation and processing, provide a valuable source for developing biodegradable packaging. Researchers have successfully transformed banana waste into innovative, recyclable, and eco-friendly packaging solutions, promoting a circular economy. Biodegradable packaging, in contrast to traditional materials derived from fossil …


Assessing The Organic Acids-Solubilized Collagen Derived From The Skin Of Unicornfish (Naso Reticulatus Randall, 2011) On Physicochemical And Structural Characteristics: Toward Alternative Source For Industrial Applications, Dayang Fazrianie Harianto, Abdul Aziz Jaziri, Rossita Shapawi, Ruzaidi Azli Mohd Mokhtar, Wan Norhana Md. Noordin, Masmunira Rambli, Nurul Huda 2024 Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia

Assessing The Organic Acids-Solubilized Collagen Derived From The Skin Of Unicornfish (Naso Reticulatus Randall, 2011) On Physicochemical And Structural Characteristics: Toward Alternative Source For Industrial Applications, Dayang Fazrianie Harianto, Abdul Aziz Jaziri, Rossita Shapawi, Ruzaidi Azli Mohd Mokhtar, Wan Norhana Md. Noordin, Masmunira Rambli, Nurul Huda

ASEAN Journal on Science and Technology for Development

Converting skin by-product of unicornfish (Naso reticulatus Randall, 2011) into a valuable commodity like collagen is a good strategy to explore alternative sources for land-based animals. Additionally, marine fish collagens are preferable due to their safer and great properties. This project aimed to compare extractability of collagens prepared with three organic acids (i.e., acetic, lactic and citric acids), and their characteristics were also discussed. Collagen extracted with citric acid (CSCUS) (7.10%) had a significantly higher yield (p


Antioxidant And Antimicrobial Properties Of Yellow Mealworm (Tenebrio Molitor) Protein Concentrates And Hydrolysates Derived From Varied Dietary Regimens, Shyang-Pei Hong, Eng-Tong Phuah, Wey-Lim Wong, Yee-Ying Lee, Teck-Kim Tang, Ali Yassoralipour 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Antioxidant And Antimicrobial Properties Of Yellow Mealworm (Tenebrio Molitor) Protein Concentrates And Hydrolysates Derived From Varied Dietary Regimens, Shyang-Pei Hong, Eng-Tong Phuah, Wey-Lim Wong, Yee-Ying Lee, Teck-Kim Tang, Ali Yassoralipour

ASEAN Journal on Science and Technology for Development

The larval stage of the darkling beetle, Tenebrio molitor, often referred to as the yellow mealworm, has received significant attention as a promising source of high-quality protein for human consumption due to its exceptional nutritional profile. This study focused on assessing the antioxidant and antimicrobial activities of protein concentrates and hydrolysates obtained from mealworm specimens raised under distinct dietary conditions. One cohort of mealworms was sustained on food waste comprising rice bran, milled corn, and carrots (self-bred) (SM), while another group was exclusively provided with rice bran (commercially fed) (CM). Enzymatic hydrolysis of mealworm protein was accomplished using protease enzymes …


Assessment Of Novel Plant-Based Fat Efficiency In Comminuted Chicken Meat System, Salma Mohamad Yusop, Shu Jo Lin, Nurkhuzaiah Kamaruzaman, Nurlisa Mohd Azhari 2024 Department of Food Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Selangor, Malaysia

Assessment Of Novel Plant-Based Fat Efficiency In Comminuted Chicken Meat System, Salma Mohamad Yusop, Shu Jo Lin, Nurkhuzaiah Kamaruzaman, Nurlisa Mohd Azhari

ASEAN Journal on Science and Technology for Development

The composition of fats and oils significantly impacts the flavour, nutrition, and appearance of food. Excessive consumption of saturated fatty acids, primarily found in animal fats, raises the risk of coronary heart disease. To address this, plant-based fats are used as substitutes, with microalgae offering unique nutritional benefits as a fat source. This study evaluates the performance of structured plant-based fats, incorporating microalgae (Aurantiochytrium sp. SW1), as a fat substitute in chicken patties. Four formulations were tested: 0% (control), 5%, 7%, and 10% structured microalgae-based fat. Colour, texture, water-holding capacity, cooking loss, and microstructure in both raw and cooked samples …


Non-Invasive Digital Refractometer To Measure Maturation Of Climacteric Fruits, Jhoorhanah A. Halim, Denni Kurniawan, Dina S. Laila, Allysa Norjemee, Nuur A. L. Nesseruddin, Asrarul A. Noraidi, Beston F. Nore 2024 Food Science and Technology Programme Area, School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Gadong, Brunei Darussalam

Non-Invasive Digital Refractometer To Measure Maturation Of Climacteric Fruits, Jhoorhanah A. Halim, Denni Kurniawan, Dina S. Laila, Allysa Norjemee, Nuur A. L. Nesseruddin, Asrarul A. Noraidi, Beston F. Nore

ASEAN Journal on Science and Technology for Development

Sugar content is a superior quality indicator for the post-harvesting and ripening status of climacteric fruits. Total soluble solids (TSS) represented by °Brix index is a measure of the sugar content. The conventional way to measure TSS is by invasive (IN) technique using manual or digital refractometers. While non-invasive (NIN) infrared refractometer devices have been developed in recent years for various agricultural and food science applications, its accuracy to measure fruit TSS directly is not straightforward, as the device is only dedicated to uses for a specific fruit. This study aims to investigate the suitability of the use of a …


Formulation Of Naturally Flavoured Mineral Water With Curcuma Longa, Zumirra Affno, Aida M. Basri, Beston F. Nore 2024 Food Science and Technology, School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Mukim Gadong BE1410, Brunei Darussalam.

Formulation Of Naturally Flavoured Mineral Water With Curcuma Longa, Zumirra Affno, Aida M. Basri, Beston F. Nore

ASEAN Journal on Science and Technology for Development

Natural, organic flavoured beverages have become an increasingly important market in the food industry due to flavour and sensory requirements among consumers. Throughout human history, herbs and spices provide a spectrum of natural food flavouring, which became an eminent component of food preparations worldwide. However, their applications in beverages have not been fully exploited. The main objective of this study is to develop flavoured water formulation based on organic turmeric extracts from flower, leaf, and rhizome parts. We adhered the natural mineral water flavouring integrity at refrigerated storage condition (4oC) for a period of 12 weeks. The flavoured water was …


Food Labelling Practices Of Local Products In Brunei Darussalam, Asrarul A. Noraidi, Zikri Zulkifli, Aida M. Basri, Ernina Rani, Beston F. Nore 2024 Food Science and Technology, School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Mukim Gadong BE1410, Brunei Darussalam

Food Labelling Practices Of Local Products In Brunei Darussalam, Asrarul A. Noraidi, Zikri Zulkifli, Aida M. Basri, Ernina Rani, Beston F. Nore

ASEAN Journal on Science and Technology for Development

Food labelling is an essential feature for food product marketing and is mainly regulated by national food authority. Food package labelling provides information on product composition, usage instructions, shelf-life safety, storage conditions, and nutritional profile. The purpose of this study is to review the scope of the current food labelling system used in local food products. We surveyed 3 different food categories: 1) processed meat products, 2) bread, and 3) snacks, and examined the nutritional labelling criteria with respect to the carbohydrates, protein, and particularly sodium (salt) content. A broad market survey was carried out across Brunei and Muara district, …


Nanocellulose Synthesized From Sugarcane Bagasse (S. Officinarum) Via Alkaline-Mechanical Process And Its Characterization, Wafiqah Daim, Hiroshi Uyama, Syazana Abdullah Lim 2024 Food Science and Technology, School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Gadong, BE1410, Bandar Seri Begawan, Brunei Darussalam

Nanocellulose Synthesized From Sugarcane Bagasse (S. Officinarum) Via Alkaline-Mechanical Process And Its Characterization, Wafiqah Daim, Hiroshi Uyama, Syazana Abdullah Lim

ASEAN Journal on Science and Technology for Development

Nanocellulose is one of many promising materials that have garnered the attention of researchers and industries. In this study, sugarcane bagasse (S. officinarum) was used to synthesize cellulose nanofiber (SB-CNF) via an alkaline-mechanical process. A comprehensive characterization of SB-CNF was conducted to explore its morphology via scanning electron microscopy (SEM) and dynamic force microscopy (DFM), assess its functional groups using Fourier transform infrared spectroscopy (FT-IR), analyze its thermal properties through thermogravimetric analysis (TGA), and lastly, evaluate light absorbance and transmittance using a UV-VIS spectrophotometer. Our findings revealed that SB-CNF resulted in a highly intertwined nanofiber structure within a nano-scale dimension. …


Protein Content Analysis On Brunei Delicacies: Kelupis Sulang And Sulang Fruit, Siti Nadia Saifullzan, Jhoorhanah A. Halim, Mas M. Rambli, Aida M. Basri 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Protein Content Analysis On Brunei Delicacies: Kelupis Sulang And Sulang Fruit, Siti Nadia Saifullzan, Jhoorhanah A. Halim, Mas M. Rambli, Aida M. Basri

ASEAN Journal on Science and Technology for Development

Traditional Bruneian delicacy which are often reserved for special occasions; called the kelupis Sulang made from glutinous rice, coconut milk, and the flesh of the Brunei Sulang fruit’s protein content were studied. The protein content of both kelupis and the sulang fruit were examined using both qualitative and protein concentration analyses. The analysis was performed using the Xanthoproteic test, Ninhydrin test, Sulphur Reduction test, and the Biuret test. The readings were obtained from the UV-Visible Spectrophotometry and revealed an average protein concentration of 21 mg/ml in aqueous extracts of kelupis sulang and 26.8 mg/ml in aqueous suspension of kelupis sulang …


Nutritional Quality Of Cultured Giant Freshwater Prawns (Macrobrachium Rosenbergii), Nurul F.M.S. Rizal, Najeebah A. Tashim, Zuhairi Azahari, Aida M. Basri, Tiong H. Lim, Aqilah Junaidi, Suriayati Chuprat, Seno A. Putra, Hanif Fakhrurroja 2024 School of Applied Sciences and Mathematics, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei Darussalam

Nutritional Quality Of Cultured Giant Freshwater Prawns (Macrobrachium Rosenbergii), Nurul F.M.S. Rizal, Najeebah A. Tashim, Zuhairi Azahari, Aida M. Basri, Tiong H. Lim, Aqilah Junaidi, Suriayati Chuprat, Seno A. Putra, Hanif Fakhrurroja

ASEAN Journal on Science and Technology for Development

Macrobrachium rosenbergii, or the giant freshwater prawn has high market demand due to its exceptional nutritional value for the human diet. Often, most nutritional studies focus on the edible prawn parts, rather than the prawn discarded components. The nutritional evaluation of different prawn parts can provide insights into the nutrient composition and guiding for the development of value-added products. Three groups of prawn samples were collected from 3 different ponds, representing different prawn sizes. The water quality analysis of each pond was also conducted to determine the extent to which it can affect the nutritional composition. The conventional and biochemical …


Rice Farmer’S Perception And Factors Influencing Intention And Attitude On Adoption Of Hybrid Rice, Ahmad Mas'Oud Muhd Halimi, Ulaganathan Subramanian 2024 UTB School of Business, Universiti Teknologi Brunei, Gadong, BA1410, Bandar Seri Begawan, Brunei Darussalam

Rice Farmer’S Perception And Factors Influencing Intention And Attitude On Adoption Of Hybrid Rice, Ahmad Mas'oud Muhd Halimi, Ulaganathan Subramanian

ASEAN Journal on Science and Technology for Development

Rice is considered the staple food of Brunei Darussalam, where most rice is imported from different countries. This poses a risk regarding food security wherein an unwanted event of restricted rice importation, Brunei, may experience difficulties. Hybrid rice cultivation is one of Brunei's best food security options. We studied the farmers' attitudes towards mixed rice farming in Brunei. We divided the farmers into two groups for the purpose of our study. Agriculture cooperative members and non-members. For attitude, perceived ease of use positively impacts attitude significantly for member rice farmers, while perceived usefulness positively impacts attitude for non-member rice farmers. …


Combating Corporate Fraud Through The Lens Of Corporate Governance In Malaysia, Emelia A. Girau, DgKu Habibah Ag Kee, Betsy Jomitin, Sazali Zainal Abidin, Imbarine Bujang 2024 Faculty of Accountancy, Universiti Teknologi MARA Sabah Branch Kota Kinabalu Campus

Combating Corporate Fraud Through The Lens Of Corporate Governance In Malaysia, Emelia A. Girau, Dgku Habibah Ag Kee, Betsy Jomitin, Sazali Zainal Abidin, Imbarine Bujang

ASEAN Journal on Science and Technology for Development

The increasing incidence of corporate fraud in major global companies has drawn significant scrutiny to the effectiveness of corporate governance in mitigating such fraudulent activities. Despite substantial improvements in corporate governance practices and the implementation of new regulatory frameworks aimed at curbing corporate fraud, instances of fraud continue to rise. If this situation persists, it will become a serious impediment to making substantial progress toward the 2030 Agenda for Sustainable Development. The objective of this study is to explore the interplay between corporate governance attributes, whistleblowing policies, and the likelihood of corporate fraud occurrences within the context of Malaysia. The …


Fostering Corporate Resilience: Assessing Risk Management Committee Effectiveness In Malaysia’S Telecommunication And Media Sector Pre- And During The Covid-19, Flicia Rimin, Siti Rahayu Beli, Anastasiah Harbi, Imbarine Bujang, Jamaliah Said 2024 Faculty of Business and Management, Universiti Teknologi MARA Sabah Branch Kota Kinabalu Campus

Fostering Corporate Resilience: Assessing Risk Management Committee Effectiveness In Malaysia’S Telecommunication And Media Sector Pre- And During The Covid-19, Flicia Rimin, Siti Rahayu Beli, Anastasiah Harbi, Imbarine Bujang, Jamaliah Said

ASEAN Journal on Science and Technology for Development

The COVID-19 pandemic has significantly impacted organizations, underscoring the critical role of financial factors in determining performance. Maintaining a healthy financial stance during crises necessitates effective risk management, prompting the exploration of a Risk Management Committee (RMC) as a focal point for addressing risk issues and managing internal controls. A study spanning 2017 to 2021 assessed 11 listed companies in the Telecommunication and Media Sector, revealing that a combined RMC did not enhance financial performance, indicating its ineffectiveness during the crisis. The study advocates for a separate risk management committee due to the audit committee’s limitations in performing both functions. …


Sustainability Innovation, Firm Competitiveness, Export Performance, And Sales Growth: A System Dynamics Approach, Budi Harsanto, Joval Ifghaniyafi Farras, Egi Arvian Firmansyah 2024 Faculty of Economics and Business, Universitas Padjadjaran, Indonesia

Sustainability Innovation, Firm Competitiveness, Export Performance, And Sales Growth: A System Dynamics Approach, Budi Harsanto, Joval Ifghaniyafi Farras, Egi Arvian Firmansyah

ASEAN Journal on Science and Technology for Development

In recent times, the interplay between sustainability innovation, firm competitiveness, export performance, and sales growth has garnered significant attention. Research on sustainable innovation's effects on firm competitiveness, export performance, and sales growth remains limited, especially concerning specific contexts like Halal Micro, Small, and Medium Enterprises (MSMEs). The study proposes to bridge this gap by developing a System Dynamics model that considers firm competitiveness, sales growth, export performance, and sustainable innovation. This research uses the system dynamic method which is carried out in four stages. The first stage, analyzing the system mechanism for sustainable innovation, the second stage, building correlations between …


Thriving In Turbulent Times: The Dynamic Link Between Economic Condition And Fintech Business Lending Success, Nur ‘Asyiqin Ramdhan, Imbarine Bujang, Amirul Afif Muhamat, Ninuk Dewi Kesumaningrum 2024 Faculty of Business and Management Universiti Teknologi MARA- Cawangan Puncak Alam, Selangor, Malaysia

Thriving In Turbulent Times: The Dynamic Link Between Economic Condition And Fintech Business Lending Success, Nur ‘Asyiqin Ramdhan, Imbarine Bujang, Amirul Afif Muhamat, Ninuk Dewi Kesumaningrum

ASEAN Journal on Science and Technology for Development

This study aimed to understand how FinTech business lending was affected by the pandemic crisis, which caused small businesses to struggle with limited access to funds. During this crisis, demand for alternative financing, like peer-to-peer (P2P) lending, surged. However, P2P lending faces challenges related to information imbalances, especially during crises, when transparency and economic conditions impact investor decisions in Malaysia. We examined factors like platform interest rates, loan duration, investment size, bank lending rates (BLR), inflation, and the crisis using ARDL analysis. Our long-term analysis revealed a significant positive relationship between investment size and P2P lending, while economic conditions had …


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