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Full-Text Articles in Medicine and Health Sciences

Needle Localization For Nonpalpable Breast Cancers, Murat Kapkaç, Sinan Ersi̇n, Servet Yetgi̇n, Ahmet Eldem Orhan Özbal, Emin Özdedeli̇, Rasih Yilmaz Jan 1998

Needle Localization For Nonpalpable Breast Cancers, Murat Kapkaç, Sinan Ersi̇n, Servet Yetgi̇n, Ahmet Eldem Orhan Özbal, Emin Özdedeli̇, Rasih Yilmaz

Turkish Journal of Medical Sciences

Nonpalpable breast lesions are being detected with the advent of improved mammographic techniques. Although only 20-30 % of these lesions are malignant, definitive diagnosis has usually required a needle- localization breast biopsy during a 6 year period were reviewed to determine the effect of this procedure on the diagnosis and treatment of early breast cancer. Calcifications were the most common mammographic abnormality for biopsy. Of the 62(27%) patients diagnosed with malignancy, 38 (61%) had invasive carcinoma and 24 (39%) had noninvasive carcinoma. Breast conservation was the most common form (53%) of surgical treatment in this study. Metastatic disease involving the …


Juvenile Dermatomyositis Associated With Acute Lymphocytic Leukemia, F. Ferda Özki̇nay, Sevgi̇ Mi̇r, Nuretti̇n Onur Kutlu, Caner Kabasakal, Eren Demi̇rtaş, Kaan Kavakli, Güngör Ni̇şli̇ Jan 1998

Juvenile Dermatomyositis Associated With Acute Lymphocytic Leukemia, F. Ferda Özki̇nay, Sevgi̇ Mi̇r, Nuretti̇n Onur Kutlu, Caner Kabasakal, Eren Demi̇rtaş, Kaan Kavakli, Güngör Ni̇şli̇

Turkish Journal of Medical Sciences

No abstract provided.


Specific Binding And Epitope Recognition In Lectin Subtypes, Ayşegül Ayyildiz Jan 1998

Specific Binding And Epitope Recognition In Lectin Subtypes, Ayşegül Ayyildiz

Turkish Journal of Medical Sciences

No abstract provided.


Lymphangitic Carcinomatosa And Bronchorrea In A Patient With Mucoepidermoid Tumor Of The Lung, F. Sema Oymak, Olcay Belenli, Murat Alper Jan 1998

Lymphangitic Carcinomatosa And Bronchorrea In A Patient With Mucoepidermoid Tumor Of The Lung, F. Sema Oymak, Olcay Belenli, Murat Alper

Turkish Journal of Medical Sciences

No abstract provided.


Adenoid Cystic Carcinoma Of The Breast, Mustafa Şahi̇n, Mustafa Erbi̇len, Adnan Hasanoğlu, Ertan Bülbüloğlu, Nasuhi E. Aydin Jan 1998

Adenoid Cystic Carcinoma Of The Breast, Mustafa Şahi̇n, Mustafa Erbi̇len, Adnan Hasanoğlu, Ertan Bülbüloğlu, Nasuhi E. Aydin

Turkish Journal of Medical Sciences

No abstract provided.


Controversy On Prophylactic Oophorectomy, Utku Özcan, Didem Akyol, Selma Oransay, Murat Ekin, Tayfun Güngör, Oya Gökmen Jan 1998

Controversy On Prophylactic Oophorectomy, Utku Özcan, Didem Akyol, Selma Oransay, Murat Ekin, Tayfun Güngör, Oya Gökmen

Turkish Journal of Medical Sciences

The merits of prophylactic oophorectomy at the time of hysterectomy have been debated for many years. The most compelling argument for prophylactic removal of the ovaries has always been the prevention of ovarian cancer (2). Prophylactic oophorectomy has advantages and disadvantages. The actual incidence of cancer in retained ovaries is difficult to estimate. The advantages of prophylactic oophorectomy include the prevention of ovarian cancer, the alleviation of symptoms from residual ovary syndrome and the elimination of the need for reoperation for adnexal disease (2). Disadvantages include surgical castration, which results in the need for hormone replacement, and changes in self-image …


Amino Acid Neurotransmitter Levels In Thecerebral Cortex Of Mice Receivingimipenem/Cilastatin -Lack Of Excitotoxicity In Thecentral Nervous System, Mete Akisü, Nilgün Kültürsay, Canan Çoker, Çiler Akisü, Meral Baka Jan 1998

Amino Acid Neurotransmitter Levels In Thecerebral Cortex Of Mice Receivingimipenem/Cilastatin -Lack Of Excitotoxicity In Thecentral Nervous System, Mete Akisü, Nilgün Kültürsay, Canan Çoker, Çiler Akisü, Meral Baka

Turkish Journal of Medical Sciences

Imipenem, a very potent carbapenem derivative beta-lactam antibiotic, has recently found a major place in the treatment of antibiotic-resistant nosocomial infections. However, a convulsive side effect is seen in 0.2-3 percent of patients. Although it is suggested that this effect is due to the inhibition of gamma-aminobutyric acid (GABA) mediated inhibitory transmission, no study has been reported so far showing its effect on the cerebral cortex free inhibitory and excitatory amino acid levels. Twenty-one male TO albino mice were divided into three equal groups and given therapeutic (40 mg/kg/day) or excessive (500 mg/kg/day) doses of Imipenem/cilastatine (I/C) or saline solution …


Anatomic And Hrct Demonstration Ofmidline Sternal Foramina, Zühre Aslı Aktan, Recep Savaş Jan 1998

Anatomic And Hrct Demonstration Ofmidline Sternal Foramina, Zühre Aslı Aktan, Recep Savaş

Turkish Journal of Medical Sciences

Midline sternal foramina are uncommon anomalies. Because of this, it is possible to mistakenly identify such a defect as defect as a gunshot wound or sternal disease by CT. In this study the frequency of midline sternal foramina in Turkish adults is investigated by high resolution computed tomography (HRCT) and visual inspection of sternal bones.


A Study On The Interparietal Bone In Man, Ferruh Yücel, Hulusi Eği̇lmez, Zehra Akgün Jan 1998

A Study On The Interparietal Bone In Man, Ferruh Yücel, Hulusi Eği̇lmez, Zehra Akgün

Turkish Journal of Medical Sciences

In the present study a total of 44 dry skulls and 500 skull films from the Sivas region of Turkey were examined to determine whether or not the interparietal bone was present. The incidence of interparietal bones was found to be 2.8 percent (15/544).


Plasma Antioxidant Status And Nitrate Levels Inpatients With Hypertension Andcoronary Heart Disease, Bülent Sözmen, Cahit Kazaz, Dilek Taskiran, Leyla Aslan, Akan Akyol, Eser Yıldırım Sözmen Jan 1998

Plasma Antioxidant Status And Nitrate Levels Inpatients With Hypertension Andcoronary Heart Disease, Bülent Sözmen, Cahit Kazaz, Dilek Taskiran, Leyla Aslan, Akan Akyol, Eser Yıldırım Sözmen

Turkish Journal of Medical Sciences

In this study, we investigated first; the possible involvement of nitric oxide and antioxidant enzyme level in the pathogenesis of essential hypertension and second we investigated serum nitrite-nitrate and antioxidant enzyme activities and lipid profiles (total, HDL and LDL cholesterol, trygliceride) to determine the relationship between these parameters in atherosclerosis. 13 patients with coronary heart disease, 18 patients with essential hypertension and 16 age-matched health subjects were taken into this study. Plasma nitrite, nitrate levels were measured by Griess reaction, erythrocyter superoxide dismutase and catalase activities were determined by the methods of Misra&Fridovich and Aebi, respectively. Serum lipid analysis were …


Determination Of Ph, Fibronectin, Cholesterol,Lactate Dehydrogenase And Sialic Acid In Thedifferentiation Of Nonmalignant Andmalignant Ascites, Hülya Aksoy, Ahmet Kiziltunç, Yilmaz Aksoy, Naciye Kurtul, Ebubekir Bakan Jan 1998

Determination Of Ph, Fibronectin, Cholesterol,Lactate Dehydrogenase And Sialic Acid In Thedifferentiation Of Nonmalignant Andmalignant Ascites, Hülya Aksoy, Ahmet Kiziltunç, Yilmaz Aksoy, Naciye Kurtul, Ebubekir Bakan

Turkish Journal of Medical Sciences

Ascites, being an accumulation of excess fluid within the peritoneal cavity, is most frequently encountered in patients with cirrhosis or certain other diseases such as congestive cardiac failure, peritoneal tuberculosis and some primary or secondary peritoneal tumours. This study included 17 patients (5 females, 12 males) with malignant ascites (MA) and 23 patients (13 females, 10 males) with nonmalignant ascites (NMA). We aimed to determinet the values for total sialic acid (SA), pH, cholesterol, fibronectin, total protein concentrations and lactate dehydrogenase (LDH) activity in ascitic fluid for the differential diagnosis of ascites. While total SA, fibronectin, cholesterol, LDH and total …


Tracheopathia Osteoplastica, Adil Zamani, Ayşe Gül Zamani, Ergün Bikmaz, Oktay İmeci̇k Jan 1998

Tracheopathia Osteoplastica, Adil Zamani, Ayşe Gül Zamani, Ergün Bikmaz, Oktay İmeci̇k

Turkish Journal of Medical Sciences

No abstract provided.


Axillary Cystic Lymphangioma Presenting Inpregnancy, Fazıl Gelal, Kamil Yücel, Erdal Tuğsel, Şefik Güney Jan 1998

Axillary Cystic Lymphangioma Presenting Inpregnancy, Fazıl Gelal, Kamil Yücel, Erdal Tuğsel, Şefik Güney

Turkish Journal of Medical Sciences

No abstract provided.


A Patient With Emaciation, Fever, Massivehepatosplenomegaly And Pancytopenia Jan 1998

A Patient With Emaciation, Fever, Massivehepatosplenomegaly And Pancytopenia

Turkish Journal of Medical Sciences

No abstract provided.


Factor Vii Deficiency Presenting Withmenometrorrhagia, Gürden Gür, Mete Özdoğan, Orhan Özgür, Sedat Boyacioğlu, Hasan Telatar Jan 1998

Factor Vii Deficiency Presenting Withmenometrorrhagia, Gürden Gür, Mete Özdoğan, Orhan Özgür, Sedat Boyacioğlu, Hasan Telatar

Turkish Journal of Medical Sciences

No abstract provided.


Patients' Rights In Turkey, Şükrü Hatun Jan 1998

Patients' Rights In Turkey, Şükrü Hatun

Turkish Journal of Medical Sciences

Patient's rights primarily mean the practice of human rights and values in the field of health care services and include the rights which are considered as third generation rights. Recently, in many countries, especially in European countries, concept of health care services which give importance to patients' rights has been developed. Patients' rights in Turkey is one of the least known issues and remembered only by physicians' malparactises causing death or disabilities some of which are speculative. Efforts are needed to strengthen the patients' rights should be accelerated in order to protect the patients and physicians from unnecessary speculations in …


Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü Jan 1998

Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü

Turkish Journal of Medical Sciences

The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes. The adhesin was extracted using dithiothreitol and iodoacetamide. It did not inhibit the adhesion of the yeast-form C. albicans to buccal epithelial cells (BEC). This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.


The Role Of Ultrafiltration Therapy On Bloodpressure Of Hypertensive Chronic Hemodialysischildren, Caner Kabasakal, Sevgi Mi̇r, Ferah Sönmez, Nermin Beti̇n, Alpan Cura, Ruhi Özyürek Jan 1998

The Role Of Ultrafiltration Therapy On Bloodpressure Of Hypertensive Chronic Hemodialysischildren, Caner Kabasakal, Sevgi Mi̇r, Ferah Sönmez, Nermin Beti̇n, Alpan Cura, Ruhi Özyürek

Turkish Journal of Medical Sciences

Hypervolemia is supposed to be the principal factor in hypertension in chronic hemodialysis adults. In this study, the role of intensive ultrafiltration (UF) treatment to reduce hypertension due to hypervolemia in hemodialysis children was investigated. The inferior vena cava (IVC) was also evaluated as an index of UF therapy. Twenty-three hemodialysis children with the mean age 10.6±3.1 years were classified due to their blood pressure status. IVC measurements were performed with 2-D echocardiography and inferior vena cava index (IVCI) was calculated as diameter of inferior vena cava (mm)/ body surface area (m 2 ). UF therapy was applied to each …


Medullary Thyroid Carcinoma: Review Of27 Cases, Yasemin Onaran, Harika Oguz, Tarık Terzi̇oğlu, Serdar Tezelman Jan 1998

Medullary Thyroid Carcinoma: Review Of27 Cases, Yasemin Onaran, Harika Oguz, Tarık Terzi̇oğlu, Serdar Tezelman

Turkish Journal of Medical Sciences

Medullary thyroid carcinoma (MTC) may present in various clinical forms, either sporadic or a counterpart of hereditary endocrine disorders. The appropriate surgical procedure for MTC is total thyroidectomy combined with central neck clearance. The aim of this study was to document the initial clinical presentation, surgical treatment and clinical course of MTC in 27 patients. Thirteen (48.1%) cases were diagnosed as hereditary, either MEN 2a(7/27, 25.9%) or 2b syndrome (1/27, 3.7%) or familial non-MEN MTC (5/27, 18.5%), and fourteen cases were diagnosed as sporadic. Eighteen primary thyroid operations and twelve reoperative surgical procedures were performed on 24 patients. Eleven of …


The Role Of Leukotrienes In The Pathogenesis Ofsteroid-Sensitive Nephrotic Syndrome, Sevgi Mi̇r, Afig Hüseyi̇nov, Mehmet Kantar, Caner Kabasakal, Alphan Cura, Işıl Çoker Jan 1998

The Role Of Leukotrienes In The Pathogenesis Ofsteroid-Sensitive Nephrotic Syndrome, Sevgi Mi̇r, Afig Hüseyi̇nov, Mehmet Kantar, Caner Kabasakal, Alphan Cura, Işıl Çoker

Turkish Journal of Medical Sciences

Endogenous leukotrienes (LT) levels in plasma and urine samples, and LT levels released from stimulated leukocytes in vitro were examined in children with steroid sensitive nephrotic syndrome (SSNS). Plasma LT concentrations were found to be higher in the SSNS group than in healthy subjects. Subjects with SSNS were also shown to have high levels of urinary cysteinyl-LTs and LTB 4 , while healthy children had only urinary LTE 4 levels. In the second part of the study, peripheral leukocytes of patients and heatlhy children were stimulated by Ca ionophore, A23187. We detected significantly higher levels of LTs in patients with …


How Hyperosmolar Solutions (Glucose 30%) Mayprevent Stress Induced Ulcers In Rats, Mustafa Yandi, Nazim Ağaoğlu, Tevhide Sel, Nihat Mansur Jan 1998

How Hyperosmolar Solutions (Glucose 30%) Mayprevent Stress Induced Ulcers In Rats, Mustafa Yandi, Nazim Ağaoğlu, Tevhide Sel, Nihat Mansur

Turkish Journal of Medical Sciences

It is accepted that administration of hyperosmolar solutions (glucose 30%) prevent stress-induced ulcers in the rats; but their mechanisms of action are not elucidated. In this study, we have investigated whether glucose is absorbed or not through the gastric wall. C14 labelled glucose solution of 30% was given to groups A (n=6), and B (n=8) and physiologic serum to group C(n=7). Restriction of movement with cold application was performed in group B and C. Ulcer indexes were 0.56±0.12 in group A, 0.83±0.27 in group B and 1.63±0.43 in group C. Net absorption rates were 12.2±4.8 %, 23.01±8.3 % and 53.1±4.65 …


The Frequency Of Chromosomal Abnormalities Inmen With Azoospermia Andoligoasthenoteratozoospermia: A Preliminarystudy, Cüneyt Tüzün, Kubilay Vi̇cdan, Semra Kahraman, Suat Özgür, Ahmet Z. Işik, Kutay Bi̇beroğlu Jan 1998

The Frequency Of Chromosomal Abnormalities Inmen With Azoospermia Andoligoasthenoteratozoospermia: A Preliminarystudy, Cüneyt Tüzün, Kubilay Vi̇cdan, Semra Kahraman, Suat Özgür, Ahmet Z. Işik, Kutay Bi̇beroğlu

Turkish Journal of Medical Sciences

The aim of this study is to investigate the frequency of chromosomal abnormalities in men with severe andrological infertility, In 50 men with azoospermia and severe oligoasthenoteratozoospermia (OAT), who referred for our intracytoplasmic sperm injection program, a cytogenetic study has been prospectively carried out. Peripheral blood lymphocytes were cultured for chromosomal analysis and for each proband 30 metaphases were analyzed by GTG banding technique. Major chromosomal abnormalities were detected in 4 of cases (8%). There were 3 sex-chromosome abnormalities, 46XXY in all 3 cases, and one autosomal chromosomal abnormality 46 XY, t (1;7) (P32;Q32). Although the sample size is small, …


Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇ Jan 1998

Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇

Turkish Journal of Medical Sciences

No abstract provided.


Hepatoerythropoietic Porphyria And Cerebralabnormalities, Mehmet Helvaci, Buket Özkaya, Işın Yaprak, Üstün Ezer Jan 1998

Hepatoerythropoietic Porphyria And Cerebralabnormalities, Mehmet Helvaci, Buket Özkaya, Işın Yaprak, Üstün Ezer

Turkish Journal of Medical Sciences

No abstract provided.


Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan Jan 1998

Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan

Turkish Journal of Medical Sciences

Although functional alterations in the central nervous system (CNS) and peripheral nerves are well documented in overt hypothyroidism, little is known about alterations of CNS in acute hypothyroidism. Sixteen patients with differentiated thyroid carcinoma were studied when prepared for radioiodine scanning after stopping levothyroxine (LT 4 ) therapy for 6 weeks to determine whether acute hypothyroidism leads to alteration in brainstem auditory evoked potentials (BAEPs). Repeat BAEPs were performed on the same patients at 6 months of the following L-T 4 therapy when patients were eu-thyroid. Neurophysiological findings were compared with a group of 20 normal controls with no hystory …


Visual Evoked Potentials In Diabetic Patients, Ömer Azal, Abdullah Özkardeş, M. Emin Önde, Metin Özata, Gökhan Özişik, Ahmet Çorakçi, M. Ali Gündoğan Jan 1998

Visual Evoked Potentials In Diabetic Patients, Ömer Azal, Abdullah Özkardeş, M. Emin Önde, Metin Özata, Gökhan Özişik, Ahmet Çorakçi, M. Ali Gündoğan

Turkish Journal of Medical Sciences

Currently there are conflicting results regarding optic neuropathy in diabetes mellitus. Therefore, the aim of the present study was to evaluate optic neuropathy in diabetic patients. We studied visual evoked potentials (VEPs) in 20 diabetic patients (6 insulin dependent, 14 noninsulin dependent; 8 women, 12 men; mean age: 49.70± 18.22 years; mean duration of diabetes: 9.33 ± 5.75 years) and 20 age-, and sex-matched healthy subjects (7 women, 13 men; mean age: 52.40 ± 16.02 years) as a control group. Nine of 20 diabetic patients had sensorimotor neuropathy, and 5 diabetic patients had both sensorimotor neuropathy and autonomic neuropathy, as …


Garnerella-Associated Vaginitis: Comparison Of Three Treatment Modalities, Şelale Özmen, Nilgün Ö. Turhan, Neslihan C. Seçki̇n Jan 1998

Garnerella-Associated Vaginitis: Comparison Of Three Treatment Modalities, Şelale Özmen, Nilgün Ö. Turhan, Neslihan C. Seçki̇n

Turkish Journal of Medical Sciences

Objective: To compare three different treatment protocols for Gardnerella va-ginalis with respect to cure rates and secondary vulvovaginal candidiasis. Methods: In this prospective randomised study, initially 2285 patients with symptoms of bacterial vaginosis were evaluated. Three hundred and seven of them in whom Gard-nerella vaginalis was recovered were eligible for the study. Group I (114 patients) was giver oral metronidazole 500mg twice daily for one week; Group II (96 patients) was prescribed oral metronidazole for one week plus a vaginal suppository of Iyophilised lactobacilli, estriol and lactose for twelve days. The third group (97 patients) was treated only with the …


Transvaginal Color Doppler Analysis Of Benign Uterine Leiomyomas, Nuri Danişman, Eyüp Eki̇ci̇, Ahmet Z. Işik, C. Gürkan Zorlu, Oya Gökmen Jan 1998

Transvaginal Color Doppler Analysis Of Benign Uterine Leiomyomas, Nuri Danişman, Eyüp Eki̇ci̇, Ahmet Z. Işik, C. Gürkan Zorlu, Oya Gökmen

Turkish Journal of Medical Sciences

In this study, the blood flow velocity waveforms of the leiomyoma, uterine artery and myometrium with color doppler ultrasound were analyzed in patients with postoperative diagnosis of benign uterine leiomyomas and 15 healthy volunteers as a control group were enrolled into the study. The lowest RI and PI values obtained from uterine leiomyomas were 0.39 and 0.93. Mean RI and PI values obtained from uterine leiomyomas were 0.39 and 0.93. Mean RI of mometrial blood flow was 0.57, while mean PI was 0.98. These measurements were done by using the color flows that were obtained from either center visualized and …


The Effects Of Wearing Of Total Prostheses Onpalatine Glands: A Morphological Study, Deniz Firat, Leyla Kuntsal, Hakan Özyuvaci, Özen Doğan, Aygen Ilicali, Mehmet Yaltirik, Yener Ayteki̇n Jan 1998

The Effects Of Wearing Of Total Prostheses Onpalatine Glands: A Morphological Study, Deniz Firat, Leyla Kuntsal, Hakan Özyuvaci, Özen Doğan, Aygen Ilicali, Mehmet Yaltirik, Yener Ayteki̇n

Turkish Journal of Medical Sciences

The purpose of this study is to examine the morphological effect which appears in acini and ductus of palatine glands in patients wearing total prostheses. Acini had considerably wide lumens due to de-generation and desquamation in secretory epithelial cells in those who wear prostheses during varying periods. It was observed that, in regions adjacent to the apical membrane in most of the epithelial cells of acini and excretory canals, large vacuoles were formed, whereas in some others, cytoplasm was disarranged due to membrane destruction. Cytoplasmic structures which were encountered in these cells underwent to degeneration and desquamation as well as …


Cytochrome P-450 Reductase Activities In Theliver Microsomes Of Diabetic Rats Induced Withsome Chemical Solvents, Yavuz Si̇li̇ğ, Öge Çeti̇nkaya Jan 1998

Cytochrome P-450 Reductase Activities In Theliver Microsomes Of Diabetic Rats Induced Withsome Chemical Solvents, Yavuz Si̇li̇ğ, Öge Çeti̇nkaya

Turkish Journal of Medical Sciences

Cytochrome P-450 Reductase enzyme is an important enzyme providing electrons to the microsomal cytochrome P-450 enzyme system metabolizing some endogenous subtances forming in the liver, drugs, chemical carcinogens insecticides and food preservation materials. In this work, it has been attempted to determine the alterations brought about in the enzyme activities by oral administering acetone, isopropanol and ethanol to chemically induced diabetic rats. The rats in whom diabetes was induced diabetic by 65 mg/kg streptozotocin (stz) were divided into four main groups as a stz alone (group I), stz + aceton (group II), stz + isopropanol (group III), stz + ethanol …