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Full-Text Articles in Medicine and Health Sciences

Prevalence Of Diabetes Mellitus And Affectedfactors In The District Of Kayseri Health Grouparea, Yusuf Öztürk, Mualla Aykut, Fahretti̇n Keleşti̇mur, Osman Günay, Fevzi̇ye Çeti̇nkaya, Osman Ceyhan, Mücahi̇t Eğri̇ Jan 2000

Prevalence Of Diabetes Mellitus And Affectedfactors In The District Of Kayseri Health Grouparea, Yusuf Öztürk, Mualla Aykut, Fahretti̇n Keleşti̇mur, Osman Günay, Fevzi̇ye Çeti̇nkaya, Osman Ceyhan, Mücahi̇t Eğri̇

Turkish Journal of Medical Sciences

The aim of this study was to determine the prevalence of diabetes mellitus and associated risk factors in rural Kayseri in Central Anatolia and to demonstrate whether glucometers can be used in epidemiological studies. This research was performed in Kayseri in 1994. The research population consisted of 3713 people chosen randomly among men and women of 30 years of age and over. The prevalence of diabetes mellitus was identified as 5.6 %. In addition, the prevalence of diabetes mellitus was found to be higher in men than in women, in people of 50 and over than in people of 49 …


Adult Respiratory Distress Syndrome Caused By Psittacosis, Aysun Yilmazlar, Beri̇n Özcan, Nuray Kaplan, Oya Kutlay Jan 2000

Adult Respiratory Distress Syndrome Caused By Psittacosis, Aysun Yilmazlar, Beri̇n Özcan, Nuray Kaplan, Oya Kutlay

Turkish Journal of Medical Sciences

No abstract provided.


Rh Subgroups And Kell Antigens In Patients With Thalassemia And In Donors In Turkey, Duran Canatan, Ni̇lgün Acar, Banu Kiliç Jan 1999

Rh Subgroups And Kell Antigens In Patients With Thalassemia And In Donors In Turkey, Duran Canatan, Ni̇lgün Acar, Banu Kiliç

Turkish Journal of Medical Sciences

Alloimmunization can be a significant complication of transfusion therapy in patients with thalassemia and hemoglobinopathies. The aim of this study was to investigate Rh and Kell antigens in patients with thalassemia major and in donors in Turkey. A total of 3061 donors and 155 thalassemic patients from three different blood donation centers in Turkey were the subjects of this study. Antigens of Rh and Kell were determined using the Diamed Gel Test. The results of Rh haplotype tests in the thalassemic patients were 40.0% R1, 35.8% r, 19.8% R2, 2.8% R0, 1.4% r'; and in the donors were 46.7% R1, …


Status Of Trace Elements Level In Blood Samplesof Different Age Population Of Karachi (Pakistan), Majid Mumtaz, Azhar Siddique, Nadia Mukhtar, Tabassum Mehboob Jan 1999

Status Of Trace Elements Level In Blood Samplesof Different Age Population Of Karachi (Pakistan), Majid Mumtaz, Azhar Siddique, Nadia Mukhtar, Tabassum Mehboob

Turkish Journal of Medical Sciences

No abstract provided.


Effects Of Nerve Growth Factor On Acetylcholinesterase Activity Of Injured Spinal Cord, Süleyman Baykal, Savaş Ceylan, Haydar Usul, Yüksel Ali̇yazicioğlu, Hasan Efe, Kayhan Kuzeyli̇, Soner Duru, Fadil Aktürk Jan 1999

Effects Of Nerve Growth Factor On Acetylcholinesterase Activity Of Injured Spinal Cord, Süleyman Baykal, Savaş Ceylan, Haydar Usul, Yüksel Ali̇yazicioğlu, Hasan Efe, Kayhan Kuzeyli̇, Soner Duru, Fadil Aktürk

Turkish Journal of Medical Sciences

Fourteen rats were examined and divided into two groups of 7: the control (Group a) and NGF-treated animals (Group B). All animals received a 50 g clip-compression injury to tthe spinal cord at the T9 level. In the NGF-treated animals, NGF (0.1 mg/kg NGF) was injected subcutaneously for seven days. After spinal cord injury, the mean AChE activity was 41.47±1.7122 activated substrate min/ml/gr. wet tissue and 47.52±1.471 in NGF-treated animals. The difference between Groups A and B was statistically significant (p


Cardiovascular Disease Risk Factors In Women Working In A Tobacco Plant, Bahatti̇n Adam, Abdulkeri̇m Bedi̇r, Cumhur Kilinç, Şennur Arslan, Muhli̇se Alvur Jan 1999

Cardiovascular Disease Risk Factors In Women Working In A Tobacco Plant, Bahatti̇n Adam, Abdulkeri̇m Bedi̇r, Cumhur Kilinç, Şennur Arslan, Muhli̇se Alvur

Turkish Journal of Medical Sciences

To estimate the effect of exposure to tobacco dust on lipid parameters that increase the incidence of cardiovascular disease (CVD), 70 female workers were selected from the tobacco processing section of a tobacco plant, and 55 women were selected from the administration selection as the controls. The subjects were homogeneous in terms of primary and secondary risk factors such as age, alcohol intake, menstrual status, physical activity, diet, familial hyperlipidemia and heart disease. They were divided into two subgroups, smokers and nonsmokers. Venous blood and morning urine samples were simultaneously taken from workers after a 12-14 h period without food …


Is The Serum Ca125 Level Originating Fromendometrum Influenced By Exogenous Estrogenadministration?, Neşe Ilgin Karabacak, Onur Karabacak, Bülent Tiraş, Rifat Gürsoy, Özdemi̇r Himmetoğlu, Sehri̇ Elbeg Jan 1999

Is The Serum Ca125 Level Originating Fromendometrum Influenced By Exogenous Estrogenadministration?, Neşe Ilgin Karabacak, Onur Karabacak, Bülent Tiraş, Rifat Gürsoy, Özdemi̇r Himmetoğlu, Sehri̇ Elbeg

Turkish Journal of Medical Sciences

Objectives: To assess the endometrial contribution of serum CA125 and its influence from estrogen administration in menopausal women. Desing: A randomised, controlled, prospective study. Materials and Methods: Twenty menopausal women with intact uterus and ovaries (study group) and ten cases with total hysterectomy were selected through a random table among the referred menopause patients for hormone replacement therapy. Mean ages and menopause lengths of the study and control groups were similar. Ten cases and five controls had 15 days of transdermal 100 µm/d estradiol (TE) (group 2), and similarly the other cases with five controls had estradiol were measured at …


Osteopoikilosis: Report Of A Familial Case, Ercan Tunç, Serpi̇l Savaş Jan 1999

Osteopoikilosis: Report Of A Familial Case, Ercan Tunç, Serpi̇l Savaş

Turkish Journal of Medical Sciences

No abstract provided.


Radioisotopic Evaluation Of Malignant Lung Tumors: A Technetium-99m-Methoxy-Isobutylisonitrile Study, Murathan Şahi̇n, Ayşenaz Özcan, İrem Bernay, Tarik Başoğlu, Ari̇f Engi̇n Demi̇rçali, Oğuz Uzun, Levent Erkan Jan 1999

Radioisotopic Evaluation Of Malignant Lung Tumors: A Technetium-99m-Methoxy-Isobutylisonitrile Study, Murathan Şahi̇n, Ayşenaz Özcan, İrem Bernay, Tarik Başoğlu, Ari̇f Engi̇n Demi̇rçali, Oğuz Uzun, Levent Erkan

Turkish Journal of Medical Sciences

Tumor imaging with myocardial perfusion agents has been a focal point for researchers. A kinetic study with 99m Technetium- methoxyisobutylisonitrile ( 99m Tc-MIBI) was performed to evaluate the tumor uptake of this radiopharmaceutical in lung cancer. Thirty-five patients with lung cancer were studied. In 21 (60%) patients, there were regions of high uptake of 99m Tc-MIBI in the lesions. Heart/tumor (H/T), heart/lung (H/L) and tumor/lung (T/L) ratios were obtained. H/T and H/L ratios were 1.66±0.22 and 2.10±0.28 in 2-3 min, and 1.69±0.25 and 2.14±0.27 in 29-30 min respectively. The T/L ratio was 1.28±0.10 in 2-3 min and 1.29±0.14 in 29-30 …


Lupus Anticoagulant And Anticardiolipinantibodies In Unexplained Fetal Losses, Güli̇nnaz Alper, Ege Nazan Tavmergen, Yasemi̇n Kabasakal, Taner Onat Jan 1999

Lupus Anticoagulant And Anticardiolipinantibodies In Unexplained Fetal Losses, Güli̇nnaz Alper, Ege Nazan Tavmergen, Yasemi̇n Kabasakal, Taner Onat

Turkish Journal of Medical Sciences

Lupus anticoagulant (LA) and anti-cardiolipin antibodies (ACAs) are acquired antiphospholipid antibodies (APAs), which are considered to be important markers for pregnancy losses and intrauterine fetal demise. LA and ACAs have anticoagulant effects in vitro and thrombotic effects in vivo and are considered to be the cause of recur-rent pregnancy losses (RPLs), resulting from placental vascular thrombosis and infarction. The aim of this study was to identify the most sensitive and specific method of deter-mining APA positivity and to evaluate the prevalence of APA in patients with unex-plained RPL. The experiment consisted of 25 women with unexplained RPL, the patient group, …


Psychosocial Influence Of Iddm On Children And Young Patients, Şükrü Hatun, Burhanetti̇n Kaya, Temel Yilmaz, Serpi̇l Salman, Zuhal Sağlam, Mehmet Sargin, Ahmet Şengül, Fati̇h Salman, Yücel Yilmaz Jan 1999

Psychosocial Influence Of Iddm On Children And Young Patients, Şükrü Hatun, Burhanetti̇n Kaya, Temel Yilmaz, Serpi̇l Salman, Zuhal Sağlam, Mehmet Sargin, Ahmet Şengül, Fati̇h Salman, Yücel Yilmaz

Turkish Journal of Medical Sciences

In this study, we evaluated 39 patients, who had been followed up in various centers, in order to determine the psychosocial effects of IDDM on children and young patients. The mean age of the patients was 15.58±2.29 years and the mean duration of diabetes was 4.41±3 years. We measured the depression and self-esteem scores in all patients using a standardized questionnaire for Turkish children. Depression was found in four patients (10.3%), and the self-esteem scores of all patients were within the normal range. There was no correlation betwenn depression or self-esteem scores and age, sex, puberty, duration of diabetes or …


The Effect Of Acute Exercise On Skin Potential In Trained Athletes, Uğur Tarik Turaçlar, Sena Erdal, Abdullah Arslan, Ahmet Yildiz Jan 1999

The Effect Of Acute Exercise On Skin Potential In Trained Athletes, Uğur Tarik Turaçlar, Sena Erdal, Abdullah Arslan, Ahmet Yildiz

Turkish Journal of Medical Sciences

Endosomatic electrodermal activity (skin potential level, skin potential response and latency) as an indirect indicator of sympathetic nervous system activity was measured in 22 trained athletes during resting and after acute exercise. The aim of this study was to investigate the difference in skin potential parameters in trained atheletes before and after acute exercise on a bicycle ergometer. Skin potential level (SPL) increased (p


The Report Of 59 Patients With Renalamyloidosis, Sai̇me Paydaş Jan 1999

The Report Of 59 Patients With Renalamyloidosis, Sai̇me Paydaş

Turkish Journal of Medical Sciences

We studied a group of 59 cases with renal amyloidosis. Mean age (45 male, 14 female) was 33.05±13.04 years. All of the cases had secondary amyloidosis. The causes of secondary amyloidosis were as follows: familial mediterranean fever (FMF) 18(30.5%), pulmonary tuberculosis 12(20.33%), chronic osteomyelitis 8(13.55), bronchiectasia 9(15.25%) rheumatic diseases 4(6.4%), Castleman's disease 1(1.6%), unknown etiology 7(11.86%) Hypertension was detected in 15.3% of the cases. In patients with less than 20 ml/min creatinine clearance (Ccr) hypertension was 20%. Hypotension was detected in 6 patients, all of these cases had severe hypoalbuminemia (3.5 g/day) was found in 75% of cases. Daily proteinuria …


Hemangioma Of The Lumbar Sympatheticganglion, Fahri̇ Yilmaz, Ali̇ Kemal Uzunlar, Mehmet Yaldiz, Adem Arslan, Cemal Özçeli̇k Jan 1999

Hemangioma Of The Lumbar Sympatheticganglion, Fahri̇ Yilmaz, Ali̇ Kemal Uzunlar, Mehmet Yaldiz, Adem Arslan, Cemal Özçeli̇k

Turkish Journal of Medical Sciences

No abstract provided.


The Role Of Plasma Endothelin-1 In Preeclampsia, Yalçın Ki̇mya, Candan Cengi̇z, Hakan Ozan, Levent Büyükuysal, Sami Aydin, Serhat Tatlikazan Jan 1999

The Role Of Plasma Endothelin-1 In Preeclampsia, Yalçın Ki̇mya, Candan Cengi̇z, Hakan Ozan, Levent Büyükuysal, Sami Aydin, Serhat Tatlikazan

Turkish Journal of Medical Sciences

Endothelin-1 levels in normal and preeclamptic pregnant women were determined serially to investigate the correlation between renal function tests and the severity markers of preeclampsia. Plasma endothelin-1 levels were determined in 45 serial plasma samples from 15 pregnant women who subsequently developed preeclampsia, and in 43 plasma samples from 25 women with uncomplicated pregnancies retrospectively. Renal function tests, complete blood counts, urinalysis and blood pressure measurements were performed during antenatal follow-ups of these patients. No correlations were set between plasma endothelin-1 levels and renal function tests, thrombocyte and white blood cell counts, proteinuria, systolic and diastolic blood pressures. There was …


Interictal Spect With Tc 99m-Hm Pao In Migrainepatients, Meral Mi̇rza, Ahmet Tutuş, Füsun Erdogan, Mustafa Kula, Ali Tomar, Güler Silov, Emel Köseoğlu Jan 1999

Interictal Spect With Tc 99m-Hm Pao In Migrainepatients, Meral Mi̇rza, Ahmet Tutuş, Füsun Erdogan, Mustafa Kula, Ali Tomar, Güler Silov, Emel Köseoğlu

Turkish Journal of Medical Sciences

Migraine is considered to be a functional neurological disorder. For several years cerebral blood flow studies have been fueling the controversy surrounding the pathophysiology of migraine headache. Tc 99m-HM PAO SPECT brain imaging was performed during the headache-free period of 29 migraine sufferers (24 without aura, 5 with aura). The findings were compared with those of an age-and sex-matched control group of 17 people. The SPECT images revealed clear interhemispheric asymmetry in the right frontal, temporal and occipital lobes of the brain in the study group. Slight hypoperfusion was observed in patients who had interictal EEG abnormalities.


Serum D(-)-Lactate And Nitric Oxide (No) Levels Inacute Intestinal Ischemia, Mahmut Basoğlu, Ahmet Balik, Ahmet Kiziltunç, Fatih Akçay, Selçuk Sabri Atamanalp Jan 1999

Serum D(-)-Lactate And Nitric Oxide (No) Levels Inacute Intestinal Ischemia, Mahmut Basoğlu, Ahmet Balik, Ahmet Kiziltunç, Fatih Akçay, Selçuk Sabri Atamanalp

Turkish Journal of Medical Sciences

To determine serum D(-)-lactate and NO levels in patients with acute mesenteric ischemia. 22 patients (12 with acute mesenteric ischemia, 10 with bowel obstruction) and 12 control patients who were operated due to goitre. Serum D(-)-lactate and NO levels in acute mesenteric ischemia cases compared to small bowel obstruction cases and control patients. Increased serum D(-)-lactate and NO levels in serum levels of ischemic bowel were found to be significantly increased compared to both the cases with small bowel obstruction and control subjects (for D(-)-lactate: p


Serum Il-6 And Tnf-\Alpha In Patients With Thyroid Disorders, Ahmet Kiziltunç, Mahmut Basoğlu, Bahattin Avci, İlyas Çapoğlu Jan 1999

Serum Il-6 And Tnf-\Alpha In Patients With Thyroid Disorders, Ahmet Kiziltunç, Mahmut Basoğlu, Bahattin Avci, İlyas Çapoğlu

Turkish Journal of Medical Sciences

The study was designed to evaluate IL-6 and TNF-\alpha levels and to examine their relationship in 27 patients with hyperthroidism, 23 with hypothyroidism, and 18 with normal thyroid functions. Mean serum levels of IL-6 and TNF-\alpha in patients with untreated hyperthyroidism were higher than those of control group (p


Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill Jan 1999

Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill

Turkish Journal of Medical Sciences

Urinary-tract infection (UTI) is one of the most common infectious diseases in children; however, the significance of combined infection in the pathogenesis of UTI remains uncertain. Of 48,382 patients discharged from Texas Children's Hospital from July 1, 1991, to June 30, 1994, 1,221 (2.5%) were discharged with a diagnosis of UTI. We retrospectively reviewed the files of these 1,221 patients to assess for concomitant infections and causative microorganisms in patients with first-time UTI, no urologic abnormalities, and no other major diagnoses. Of the 1,221 patients, 511 (42%) had first-time UTI with no urological abnormalities or other major diagnoses, of which …


Pupil Cycle Time In Children With Nocturnal Enuresis, Cengiz Yakinci, Hamdi Er, Bülent Müngen, Yaşar Durmaz, Hamza Karabi̇ber Jan 1999

Pupil Cycle Time In Children With Nocturnal Enuresis, Cengiz Yakinci, Hamdi Er, Bülent Müngen, Yaşar Durmaz, Hamza Karabi̇ber

Turkish Journal of Medical Sciences

No abstract provided.


A Case Of Pheochromocytoma Manifested As Noncardiogenic Pulmonary Edema, Tuncer Tuğ, Necmi Özdemi̇r, Vedat Bulut, Aziz Karaoğlu, M.Hamdi Muz Jan 1999

A Case Of Pheochromocytoma Manifested As Noncardiogenic Pulmonary Edema, Tuncer Tuğ, Necmi Özdemi̇r, Vedat Bulut, Aziz Karaoğlu, M.Hamdi Muz

Turkish Journal of Medical Sciences

Pheochromocytoma is known as chromaffin cell tumor frequently originated from adrenal medulla and results in hypersecretion of catecholamines (1). Typical clinical findings include headache, palpitation, excessive sweating and paroxysmal hypertension, which persistently maintains in 60% of the cases. Generally, paroxysm or attacks are often, but they can appear with intervals of weeks or months (1, 2). Additionally, tachycardia, bradycardia and/or fatal arrhythmia, acute myocard infarcts, spasms in coroner arteries, carcinoid-like manifestations, hyperamilasemi, acute abdomen, chest pain, intolerance to carbohydrates, nephritic syndrome (very rare), cardiac pulmonary edema, cardiomyopathie caused by catecholamines and very rarely noncardiogenic pulmonary edema may develop (3, 4, …


Hydrotic Ectodermal Dysplasia(Associated With Numerous Enclusedpermanent Teeth Including A Primary Molar), Ali Rıza Alpöz Jan 1999

Hydrotic Ectodermal Dysplasia(Associated With Numerous Enclusedpermanent Teeth Including A Primary Molar), Ali Rıza Alpöz

Turkish Journal of Medical Sciences

No abstract provided.


Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener Jan 1999

Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener

Turkish Journal of Medical Sciences

No abstract provided.


Ultrastructural And Morphometric Analysis Ofperipheral Nerve Regenerationwithin Silicone Tubes, Leyla Canpolat, Aysel Kükner, İbrahi̇m Canpolat, Enver Ozan Jan 1999

Ultrastructural And Morphometric Analysis Ofperipheral Nerve Regenerationwithin Silicone Tubes, Leyla Canpolat, Aysel Kükner, İbrahi̇m Canpolat, Enver Ozan

Turkish Journal of Medical Sciences

Semi-thin and thin sections were used to observe the morphogenesis of peripheral nerves regenerating in silicone tubes. The progress of peripheral nerve regeneration across a 10 mm gap within the silicone tubes was examined after 3, 6 and 9 months. The left sciatic nerves of rats were transected. The proximal and distal nerve stumps were inserted into a silicone tube, in which they were separeted by a 10 mm gap. A tissue cable formed inside the silicone tube with regenerated axons. In the 3rd month, the 10 mm gap was bridged by a structure composed of regenerating axons, blood vessels …


Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan Jan 1999

Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan

Turkish Journal of Medical Sciences

In the present study, we aimed to investigate the effects of dietary salt restriction and loading on extracellular fluid volume (ECFV), blood pressure (BP), heart rate (HR), glomerular filtration rate (GFR) and renal hypertrophy in diabetic rats. Diabetes was induced by injection of streptozotocin (STZ, 65 mg/kg, iv) into male Wistar rats. Four groups were formed: a) the diabetic rats given a standard rat diet (DC), b) the diabetic rats given a high-salt diet (DHS), c) the diabetic rats given a low-salt diet (DLS), d) the nondiabetic rats given a standard rat diet (C). Salt loading and salt restriction were …


The Effects Of Rumex Patientia L. And Urticadioica L. On Some Blood And Urine Parameters,And Liver And Kidney Histology In Diabetic Rats, Hasan V. Güneş, İrfan Deği̇rmenci̇, Mi̇ri̇ş Aydin, Berri̇n Bozan, Eri̇nç Aral, Zeynep Tunalier, Cengi̇z Üstüner, Murat Erçakar, K. Hüsnü Can Başer, Ayşe Başaran Jan 1999

The Effects Of Rumex Patientia L. And Urticadioica L. On Some Blood And Urine Parameters,And Liver And Kidney Histology In Diabetic Rats, Hasan V. Güneş, İrfan Deği̇rmenci̇, Mi̇ri̇ş Aydin, Berri̇n Bozan, Eri̇nç Aral, Zeynep Tunalier, Cengi̇z Üstüner, Murat Erçakar, K. Hüsnü Can Başer, Ayşe Başaran

Turkish Journal of Medical Sciences

The effects of Rumex patientia and Urtica dioica on levels of blood glucose, plasma amino acids and other parameters, urine excreta, and liver and kidney histology were examined in diabetic rats induced by streptozotocin. Streptozotocin increased blood glucose and changed the levels of amino acids and other parameters, and caused degenerative changes in the liver and kidney. Rumex patientia had some protective effect on these parameters changed by streptozotocin, while Urtica diocia had no protective effects.


The Anti-Inflammatory Effects Of N^G-Nitrol-Arginine (L-Name) And Steroid In Concanavalina-Induced Uveitis, Hamdi̇ Er, Erhan Üzmez, Naki̇ Doğan, Tongabay Cumhurcu Jan 1999

The Anti-Inflammatory Effects Of N^G-Nitrol-Arginine (L-Name) And Steroid In Concanavalina-Induced Uveitis, Hamdi̇ Er, Erhan Üzmez, Naki̇ Doğan, Tongabay Cumhurcu

Turkish Journal of Medical Sciences

The objective of this study was to compare the anti-inflammatory effects of NG -nitro L-arginine (L-NAME) and corticosteroid in Concanavalin A-induced uveitis in rats. Sixteen male Wistar rats were used. After general anesthesia, intravitreal 0.1 ml Concanavalin A (100mg/ml) was injected into the left eyes of the rats. The animals were divided into 3 groups: group 1 (6 animals) received intraperitoneal 0.2 ml L-NAME (200 mg/kg) 1 hour before, 1 day and 3 days after Concanavalin A injection, group 2 (6 animals) received tropical 1% prednisolone acetate four times a day for 3 weeks, group 3 (4 animals) received an …


Immunohistochemical Localization Of Thymosin\Beta_4 In Bovine Tissuesourania E. Tsitsilonis 1, Ourania E. Tsitsilonis, Ayhan Ulubelen, Stanka Stoeva, Mirna Mihelic Rapp, W. Giebel, Rai̇ner Lehmann, Wolfgang Voelter Jan 1999

Immunohistochemical Localization Of Thymosin\Beta_4 In Bovine Tissuesourania E. Tsitsilonis 1, Ourania E. Tsitsilonis, Ayhan Ulubelen, Stanka Stoeva, Mirna Mihelic Rapp, W. Giebel, Rai̇ner Lehmann, Wolfgang Voelter

Turkish Journal of Medical Sciences

The histochemical localization of thymosin \beta_4 was investigated for the first time in several bovine tissues, using the indirect immunofluorescent technique and the newly applied alkaline phosphatase anti-alkaline phosphatase (APAAP) antibody method. A polyclonal antiserum raised against the N-terminal fragment (1-14) of thymosin \beta_4, showing less than 0.1% crossreactivity with the second b-thymosin in calf tissues, thymosin \beta_9, was used. Positive reaction for thymosin \beta_4 was observed in the cytoplasm of all tissues studied, i.e., bovine spleen, thymus, lung, liver, kidney, lymph nodes and cardiac muscle. The highest staining intensity was found in the cytoplasmic area of spleen and thymus, …


Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n Jan 1999

Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n

Turkish Journal of Medical Sciences

This study was planned to compare recurrence of goiters after thyroidectomy in patients who received prophylactic levothyroxine and patients who received no therapy. One hundred and twenty-six patients had been treated by bilateral subtotal thyroidectomy in the General Surgery Clinic of Karadeniz Technical University from 1987 to 1992. Eithy-eight of these patients were included in this study while the remaining patients were excluded as they were non contactable. They were divided into two groups. In group 1, there were 41 patients who had received prophylactic therapy with thyroxine 100 micro grams daily for a period of 9 to 12 months. …


Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci Jan 1999

Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci

Turkish Journal of Medical Sciences

For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p