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Full-Text Articles in Medicine and Health Sciences

The Evaluation Of The Stomatognathic System Of A Group With Anterior Openbite, Semra Ci̇ğer, Eli̇f İdi̇l Keser Jan 2004

The Evaluation Of The Stomatognathic System Of A Group With Anterior Openbite, Semra Ci̇ğer, Eli̇f İdi̇l Keser

Turkish Journal of Medical Sciences

Anterior openbite (AOB) is a malocclusion considered to be associated with symptoms and signs of temporomandibular disorders (TMD). An accurate, objective and repeatable method is needed in order to clarify the relationship between TMD and anterior openbite. The aim of this study is to examine the functions of the stomatognathic systems of 21 adolescents with AOB by means of electrovibratography (EVG), electrognathography (EMG), electroganthography (EGN), and transcranial and cephalometric radiographs. Nonconcentricity and mild asymmetry of the condyle fossa relationships were observed on transcranial radiographs. EMG results showed that 85% of the subjects had abnormal swallowing patterns and 52% had abnormal …


Case Report: Intramesocolic Malposition Of The Gallbladder, Oral Saygun, Kuzey Aydinuraz, Çağatay Daphan, Abdullah Akkus, Fati̇h Ağalar Jan 2004

Case Report: Intramesocolic Malposition Of The Gallbladder, Oral Saygun, Kuzey Aydinuraz, Çağatay Daphan, Abdullah Akkus, Fati̇h Ağalar

Turkish Journal of Medical Sciences

GUN, Kuzey AYDINURAZ, Cağatay DAPHAN, Abdullah AKKUS, Fatih AĞALAR Department of General Surgery, Faculty of Medicine, Kırıkkale University, Kırıkkale - TURKEY


Can The Natural Carbonic Anhydrase Inhibitors In Trout Plasma Be Used In The Treatment Of Some Human Diseases?, Şükrü Beydemi̇r, Olcay Hi̇sar Jan 2004

Can The Natural Carbonic Anhydrase Inhibitors In Trout Plasma Be Used In The Treatment Of Some Human Diseases?, Şükrü Beydemi̇r, Olcay Hi̇sar

Turkish Journal of Medical Sciences

No abstract provided.


The Effects Of Melatonin On 6-Phosphogluconate Dehydrogenase: An In Vitro And In Vivo Study, İlhami̇ Gülçi̇n, Şükrü Beydemi̇r Jan 2004

The Effects Of Melatonin On 6-Phosphogluconate Dehydrogenase: An In Vitro And In Vivo Study, İlhami̇ Gülçi̇n, Şükrü Beydemi̇r

Turkish Journal of Medical Sciences

Melatonin is known to influence a variety of biological processes including circadian rhythms, neuroendocrine, and cardiovascular and immune functions as well as thermoregulation. Melatonin is the chief secretory product of the pineal gland, although it is also produced in other organs. In this study, in vitro effects of melatonin on 6-phosphogluconate dehydrogenase from human erythrocytes and in vivo effects of melatonin on 6-phosphogluconate dehydrogenase from rat (Sprague-Dawley) erythrocytes were studied. Human erythrocyte 6-phosphogluconate dehydrogenase was purified in 3 steps, namely haemolysate preparation, ammonium sulphate fractionation (35-65%) and 2´,5´-ADP Sepharose-4B affinity gel chromatography. 6-Phosphogluconate dehydrogenase was purified with a recovery rate …


The Effects Of Asthma Education On Knowledge, Behavior And Morbidity In Asthmatic Patients, Rezan Demi̇ralay Jan 2004

The Effects Of Asthma Education On Knowledge, Behavior And Morbidity In Asthmatic Patients, Rezan Demi̇ralay

Turkish Journal of Medical Sciences

This work was carried out to study the effect of asthma education on asthma knowledge, behavior and morbidity in asthmatic patients. A randomized double blind controlled study was conducted with 54 adults with asthma followed-up at the outpatient clinic of Chest Diseases and Tuberculosis at the Faculty of Medicine of Suleyman Demirel University. Patients were randomized to the verbal (n: 17), written (n: 19), and verbal-written (n: 18) education groups. Knowledge of asthma was measured at the baseline, and 2 months and 1 year after education. Compliance with treatment, correct inhaler skill and admisssons to hospital in the previous year …


Abdominal Wall Endometrioma: Localizing In Rectus Abdominus Sheath, Mustafa Çeli̇k, Ertan Bülbüloğlu, Mehmet Aki̇f Büyükbeşe, Ali̇ Çeti̇nkaya Jan 2004

Abdominal Wall Endometrioma: Localizing In Rectus Abdominus Sheath, Mustafa Çeli̇k, Ertan Bülbüloğlu, Mehmet Aki̇f Büyükbeşe, Ali̇ Çeti̇nkaya

Turkish Journal of Medical Sciences

ÇELİK^1, Ertan BÜLBÜLOĞLU^2, Mehmet Akif BÜYÜKBEŞE^3, Ali ÇETİNKAYA^3 ^1Department of Family Medicine, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş - Turkey ^2Department of General Surgery, Faculty of Medicine, Kahramanmaraş Sütçü İmam University , Kahramanmaraş - Turkey ^3Department of Internal Medicine, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş - Turkey


Difficulties And Failure Of Laryngeal Mask Insertion In A Patient With Ankylosing Spondylitis, Gönül Ölmez, Hasan Nazaroğlu, Seher Gündüz Arslan, Mehmet Ali̇ Özyilmaz, Ayşe Di̇cle Turhanoğlu Jan 2004

Difficulties And Failure Of Laryngeal Mask Insertion In A Patient With Ankylosing Spondylitis, Gönül Ölmez, Hasan Nazaroğlu, Seher Gündüz Arslan, Mehmet Ali̇ Özyilmaz, Ayşe Di̇cle Turhanoğlu

Turkish Journal of Medical Sciences

MEZ^1, Hasan NAZAROĞLU^2, Seher Gündüz ARSLAN^3, Mehmet Ali ÖZYILMAZ^1, Ayşe Dicle TURHANOĞLU4 ^1Department of Anesthesiology, Faculty of Medicine, Dicle University, Diyarbakır - Turkey ^2Department of Radiology, Faculty of Medicine, Dicle University, Diyarbakır - Turkey ^3Department of Orthodontics, Faculty of Dentistry, Dicle University, Diyarbakır - Turkey ^4Physical Therapy and Rehabilitation, Faculty of Medicine, Dicle University, Diyarbakır - Turkey


Chromosomal Aberrations In Radiation Waste Repository Workers Detected By Fish Painting And Giemsa Staining, Petya Atanasova, Valeria Borisova Hadjidekova, Savina Agova, Milen Iovtchev Jan 2004

Chromosomal Aberrations In Radiation Waste Repository Workers Detected By Fish Painting And Giemsa Staining, Petya Atanasova, Valeria Borisova Hadjidekova, Savina Agova, Milen Iovtchev

Turkish Journal of Medical Sciences

We aimed to assess chromosomal aberration frequency by means of FISH chromosome painting and conventional Giemsa staining in peripheral blood lymphocytes of workers at a nuclear waste repository. The results obtained from the exposed group were compared with those from a control group from the administrative staff of the company. Data on health and social status were collected using a questionnaire. Conventional chromosomal analysis after Giemsa staining did not indicate any significant difference between radiation exposed and control workers. Analysis after FISH chromosome painting revealed a 2-fold increased in genomic frequency of stable chromosomal translocations in the exposed group over …


The Rehabilitation Results Of Hemiplegic Patients, Asuman Doğan, Güldal Naki̇poğlu, Meryem Doğan Aslan, Ayşe Z. Kaya, Neşe Özgi̇rgi̇n Jan 2004

The Rehabilitation Results Of Hemiplegic Patients, Asuman Doğan, Güldal Naki̇poğlu, Meryem Doğan Aslan, Ayşe Z. Kaya, Neşe Özgi̇rgi̇n

Turkish Journal of Medical Sciences

The aim of this study was to determine whether or not there was an improvement in the daily life activities and ambulation levels of the hemiplegic patients whom we took into our rehabilitation program. In this case series study, 92 hemiplegic patients were included in the rehabilitation program. The ages, genders, educational levels, etiologies, hemiplegic sides, hemiplegic periods and the systemic diseases of the patients included in the rehabilitation program were recorded. The daily life activities of every patient at admittance and at discharge from hospital were evaluated using the Barthel Index (BI) and ambulation levels were evaluated using the …


Primary Thyroid Lymphoma Arising In The Setting Of Hashimoto’S Thyroiditis, Banu Doğan Gün, Mustafa Özkan Gün, Zi̇ya Karamanoğlu Jan 2004

Primary Thyroid Lymphoma Arising In The Setting Of Hashimoto’S Thyroiditis, Banu Doğan Gün, Mustafa Özkan Gün, Zi̇ya Karamanoğlu

Turkish Journal of Medical Sciences

AN GÜN^1, Mustafa Özkan GÜN^2, Ziya KARAMANOĞLU^3 ^1Department of Pathology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak - Turkey ^2Department of Pathology, Zonguldak SSK City Hospital, Zonguldak, Turkey ^3Department of General Surgery, Zonguldak SSK City Hospital, Zonguldak, Turkey


An Extraskeletal Myxoid Chondrosarcoma Diagnosed By Fine Needle Aspiration Biopsy, Demet Eti̇t, Fi̇li̇z Dağ, Si̇nem Aydin Ergun, Asli Kahraman Jan 2004

An Extraskeletal Myxoid Chondrosarcoma Diagnosed By Fine Needle Aspiration Biopsy, Demet Eti̇t, Fi̇li̇z Dağ, Si̇nem Aydin Ergun, Asli Kahraman

Turkish Journal of Medical Sciences

İT, Filiz DAĞ, Sinem AYDIN ERGUN, Aslı KAHRAMAN Department of Pathology, Ataturk Training and Research Hospital, İzmir - Turkey


Congenital Megacalycosis: A Rare Renal Developmental Anomaly, Beki̇r Suha Parlaktaş, Fi̇kret Erdemi̇r, Ni̇hat Uluocak Jan 2004

Congenital Megacalycosis: A Rare Renal Developmental Anomaly, Beki̇r Suha Parlaktaş, Fi̇kret Erdemi̇r, Ni̇hat Uluocak

Turkish Journal of Medical Sciences

ha PARLAKTAŞ, Fikret ERDEMİR, Nihat ULUOCAK Department of Urology, Faculty of Medicine, Gaziosmanpaşa University, Tokat - Turkey


Apert Syndrome, İlknur Kiliç, Yildirim Baykara, C. Nur Semerci̇, Hacer Ergi̇n, N. Lale Şatiroğlu Tufan Jan 2004

Apert Syndrome, İlknur Kiliç, Yildirim Baykara, C. Nur Semerci̇, Hacer Ergi̇n, N. Lale Şatiroğlu Tufan

Turkish Journal of Medical Sciences

ILIÇ^1, Yıldırım BAYKARA^1, C. Nur SEMERCİ^2, Hacer ERGİN^1, N. Lale ŞATIROĞLU TUFAN^2 ^1 Department of Pediatrics, Faculty of Medicine, Pamukkale University, Denizli - Turkey ^2 Department of Medical Biology, Genetics Unit, Faculty of Medicine, Pamukkale University, Denizli - Turkey


Half A Century Of Dna, Di̇cle Güç Jan 2004

Half A Century Of Dna, Di̇cle Güç

Turkish Journal of Medical Sciences

No abstract provided.


Typing Of Methicillin-Resistant Staphylococcus Aureus By Ribosome Spacer And Arbitrarily Primed Polymerase Chain Reaction, Tamer Essawi, Kamel Adwan, Nael Abu-Hassan, Galeb Adwan, Ahmed Saleh, Ghaleb Mohammad Adwan Jan 2004

Typing Of Methicillin-Resistant Staphylococcus Aureus By Ribosome Spacer And Arbitrarily Primed Polymerase Chain Reaction, Tamer Essawi, Kamel Adwan, Nael Abu-Hassan, Galeb Adwan, Ahmed Saleh, Ghaleb Mohammad Adwan

Turkish Journal of Medical Sciences

Thirty-five methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates were collected from 3 hospitals in the northern and southern parts of Palestine between February and May 1998. These isolates were typed by ribosome spacer PCR (RS-PCR) and arbitrarily primed PCR (AP-PCR). RS-PCR generated 9 different genotypes. The use of AP-PCR provided a high resolution typing method and allowed us to define 11 different clusters. Three major clusters, however, based on the combination of both typing methods, spread throughout the neonatal and intensive care units of Rafidya Hospital during the entire period.


Cytotoxicity Of Low Dose Epirubicin-Hci Combined With Lymphokine Activated Killer Cells Against Hepatocellular Carcinoma Cell Line Hepatoma G2, Aysun Özkan, Kayahan Fişkin Jan 2004

Cytotoxicity Of Low Dose Epirubicin-Hci Combined With Lymphokine Activated Killer Cells Against Hepatocellular Carcinoma Cell Line Hepatoma G2, Aysun Özkan, Kayahan Fişkin

Turkish Journal of Medical Sciences

Recent evidance supports the concept that Epirubicin-HCI and Lymphokine-activated killer cells (LAK) cytotoxicity may be mediated by free radical and oxyradical generation. We tested this hypothesis further by exposing Hep G2 cells to Epirubicin-HCI and LAK cells and subsequently monitored cell viability as a measure of cytotoxicity. The cytotoxicity of LAK alone and LAK together with low dose epirubicin-HCI (IC50 1/10) which is measured using the MTT cytotoxicity test on viability of Hep G2 cells and sensitization of target cells to effector cells was investigated. The cytotoxicity of LAK (IC50 value of 5LAK/Hep G2 in 24 hours) and LAK+epirubicin-HCI (IC50 …


A Morphometric Evaluation Of Some Important Bony Landmarks On The Skull Base Related To Sexes, Aynur Emi̇ne Çi̇çekci̇başi, Khali̇l Awadh Murshid, Taner Zi̇ylan, Muzaffer Şeker, Işik Tuncer Jan 2004

A Morphometric Evaluation Of Some Important Bony Landmarks On The Skull Base Related To Sexes, Aynur Emi̇ne Çi̇çekci̇başi, Khali̇l Awadh Murshid, Taner Zi̇ylan, Muzaffer Şeker, Işik Tuncer

Turkish Journal of Medical Sciences

The purpose of this study is to evaluate the morphometric measurements of some important bony landmarks on the cranial base and to determine their relationships between the sexes and their bilateral differences. In this study, 60 (34 male and 26 female) skulls were obtained from the teaching skeletal collections at the Anatomy Department of Meram Medical School, Selçuk University. The axial length of the occipital condyles (ALOC), the anterior intercondylar distance (AICD), the sagittal intercondylar angle (OICA), the transverse and sagittal diameters of the jugular foramen (TDJF) and (SDJF), the distance from the apex of the mastoid process to the …


Juvenile Hyaline Fibromatosis: Case Presentation (The Rehabilitation Of Three Siblings), Güldal Funda Naki̇poğlu, Asuman Doğan, Meryem Doğan Aslan, Neşe Özgi̇rgi̇n Jan 2004

Juvenile Hyaline Fibromatosis: Case Presentation (The Rehabilitation Of Three Siblings), Güldal Funda Naki̇poğlu, Asuman Doğan, Meryem Doğan Aslan, Neşe Özgi̇rgi̇n

Turkish Journal of Medical Sciences

No abstract provided.


Atypical Microtia Correction With Multiple Z-Plasties, Safvet Örs, Gali̇p K. Günay Jan 2004

Atypical Microtia Correction With Multiple Z-Plasties, Safvet Örs, Gali̇p K. Günay

Turkish Journal of Medical Sciences

RS^1, Galip K. GÜNAY^2 ^1Department of Plastic Surgery, Güneş Hospital, Kayseri - Turkey ^2Department of Plastic Surgery, Faculty of Medicine, Erciyes University, Kayseri - Turkey


The Intellectual And Scientific Basis Of Parathyroid Surgery, Seza A. Güleç, Ömer Uğur Jan 2004

The Intellectual And Scientific Basis Of Parathyroid Surgery, Seza A. Güleç, Ömer Uğur

Turkish Journal of Medical Sciences

No abstract provided.


Expression Analysis Of Dek, Af4 And Fli1 Genes In All-Trans-Retinoic Acid (Atra) Treated Acute Promyelocytic Leukaemia T(15;17) Patients By Quantitative Real-Time Pcr, Hakan Savli, Sema Sirma, Balint Nagy, Meli̇h Aktan, Günçağ Di̇nçol, Zafer Salcioğlu, Uğur Özbek Jan 2004

Expression Analysis Of Dek, Af4 And Fli1 Genes In All-Trans-Retinoic Acid (Atra) Treated Acute Promyelocytic Leukaemia T(15;17) Patients By Quantitative Real-Time Pcr, Hakan Savli, Sema Sirma, Balint Nagy, Meli̇h Aktan, Günçağ Di̇nçol, Zafer Salcioğlu, Uğur Özbek

Turkish Journal of Medical Sciences

All-trans retinoic acid (ATRA) sensitivity of acute promyelocytic leukaemia (APL) cells is strictly dependent on the presence of t(15;17), but the molecular background of this sensitivity remains obscure. We showed the down- regulation of DEK, AF4 and FLI1 genes in the vitamin D treatment of APL cell line HL-60 , using cDNA array technology in our previous study. This finding prompted us to investigate the expression of these genes in APL patient samples. The effect of ATRA was studied in 6 APL patients carrying t(15;17). Two samples from each patient were compared with a primary diagnostic sample and a sample …


Evaluation Of Pulsed Electromagnetic Fields On Bone Healing After Implant Placement In The Rabbit Mandibular Model, Jüli̇de Özen, Arzu Atay, Selçuk Oruç, Mehmet Dalkiz, Bedri̇ Beydemi̇r, Sali̇h Develi̇ Jan 2004

Evaluation Of Pulsed Electromagnetic Fields On Bone Healing After Implant Placement In The Rabbit Mandibular Model, Jüli̇de Özen, Arzu Atay, Selçuk Oruç, Mehmet Dalkiz, Bedri̇ Beydemi̇r, Sali̇h Develi̇

Turkish Journal of Medical Sciences

Although bone healing around titanium implants has already been evaluated, the effect of pulsed electromagnetic fields (PEMF) during the period of bone maturation around titanium dental implants has not yet been investigated. The aim of this study was to evaluate the effects of PEMFs on bone formation following the insertion of titanium-dental implants in the rabbit mandibular model. Ti-6Al-4V (Sulzer Calcitek, California, USA) dental implants were inserted into the mandibulae of 28 New Zealand rabbits (6 weeks old). Fourteen were stimulated with PEMFs for 2 consecutive weeks, 4 h/day, at a magnetic intensity of 0.2 milli Tesla (mT), while the …


Serological Evaluation Of Hsv-1 And Hsv-2 Infection In Pregnancy, Ni̇zami̇ Duran Jan 2004

Serological Evaluation Of Hsv-1 And Hsv-2 Infection In Pregnancy, Ni̇zami̇ Duran

Turkish Journal of Medical Sciences

We performed a serological evaluation of herpes simplex virus (HSV) infections at the time of labor. In order to determine the seroprevalence of asymptomatic HSV infections in pregnant women, blood samples were collected for antibody measurement from 130 randomly selected pregnant women. Presence of HSV IgG and IgM antibodies in the serum samples was tested by ELISA. The prevalence of HSV-1 gG1 antibodies was 90% (117/130), that of HSV-2 gG2 antibodies was 63.1% (82/130) and that of HSV-2 IgM antibodies was 13.8% (18/130). Eight (44.4%) of the pregnant women with HSV-2 IgM were at the same time found to have …


Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan Jan 2004

Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan

Turkish Journal of Medical Sciences

AKDEMİR^1, Hüseyin GÜNDÜZ^2, Hakan ÖZHAN^1, Mehmet YAZICI^1, Enver ERBİLEN^1, Cihangir UYAN^2 ^1Department of Cardiology, Düzce Faculty of Medicine, Abant Izzet Baysal University, Düzce - Turkey ^2Department of Cardiology, Izzet Baysal Faculty of Medicine, Abant Izzet Baysal University, Bolu - Turkey


The Effect Of Hyperbaric Oxygen Therapy (Hbo) When Used Postoperatively In Skin Grafting Over Radiated Tissue In The Rat, Burçak Tümerdem, Ufuk Emekli̇, Burcu Çelet Özden, Şami̇l Aktaş, Mi̇sten Demi̇ryont, Gönül Kemi̇kler Jan 2004

The Effect Of Hyperbaric Oxygen Therapy (Hbo) When Used Postoperatively In Skin Grafting Over Radiated Tissue In The Rat, Burçak Tümerdem, Ufuk Emekli̇, Burcu Çelet Özden, Şami̇l Aktaş, Mi̇sten Demi̇ryont, Gönül Kemi̇kler

Turkish Journal of Medical Sciences

Under conditions that may risk the success of flap surgery, free skin grafting may be an option for the reconstruction of the irradiated area. Clinical observations reveal that skin grafts applied to irradiated area undergo ulceration, resulting in chronic open wounds. The role of hyperbaric oxygen therapy (HBO) in problem wounds is to increase the tissue oxygen tension to optimize fibroblast proliferation and collagen synthesis, to enhance the oxidative killing capacity of the white blood cells and to stimulate angiogenesis. HBO has also been shown to stimulate angiogenesis in radiation-damaged tissue. In view of this data, an animal model is …


What Is New In Wound Healing?, Senthil Kumar, Peng Foo Wong, David John Leaper Jan 2004

What Is New In Wound Healing?, Senthil Kumar, Peng Foo Wong, David John Leaper

Turkish Journal of Medical Sciences

Wound biology is complex. Wounds which were until recently seen only as defects in tissues are now increasingly interpreted in cellular and molecular terms. Growth factors, cytokines, proteases and adhesion molecules which participate in wound healing are discussed in this article. From a clinical perspective, conceptual shifts of importance, including moist wound healing, wound bed preparation and wound assessment, are presented. The frontiers of therapeutics employed in wound healing continue to advance with an increasing array of modalities joining the ranks at a regular pace. A range of currently available as well as evolving therapies- physical (topical negative pressure therapy, …


Mesenchymal Chondrosarcoma Of The Mandible, Nusret Akpolat, Üzeyi̇r Gök Jan 2004

Mesenchymal Chondrosarcoma Of The Mandible, Nusret Akpolat, Üzeyi̇r Gök

Turkish Journal of Medical Sciences

KPOLAT^1, Üzeyir GÖK^2 ^1Department of Pathology, Faculty of Medicine, Fırat University, Elazığ - Turkey ^1Department of Otorhinolaryngology, Faculty of Medicine, Fırat University, Elazığ - Turkey


Systemic Responses To Burn Injury, Bariş Çakir, Berrak C. Yeğen Jan 2004

Systemic Responses To Burn Injury, Bariş Çakir, Berrak C. Yeğen

Turkish Journal of Medical Sciences

The major causes of death in burn patients include multiple organ failure and infection. It is important for the clinician to understand the pathophysiology of burn injury and the effects it will have on the pharmacokinetics of a drug. The local and systemic inflammatory response to thermal injury is extremely complex, resulting in both local burn tissue damage and deleterious systemic effects on all other organ systems distant from the burn area itself. Thermal injury initiates systemic inflammatory reactions producing burn toxins and oxygen radicals and finally leads to peroxidation. The relationship between the amount of products of oxidative metabolism …


Genotoxic Evaluation Of The Antibacterial Drug, Ciprofloxacin, In Cultured Lymphocytes Of Patients With Urinary Tract Infection, Mevli̇t İkbal, Hasan Doğan, Hati̇ce Odabaş, İbrahi̇m Pi̇ri̇m Jan 2004

Genotoxic Evaluation Of The Antibacterial Drug, Ciprofloxacin, In Cultured Lymphocytes Of Patients With Urinary Tract Infection, Mevli̇t İkbal, Hasan Doğan, Hati̇ce Odabaş, İbrahi̇m Pi̇ri̇m

Turkish Journal of Medical Sciences

Ciprofloxacin is a quinolone carboxylic acid derivative and is commonly used in medicine. The genotoxicity of ciprofloxacin was evaluated in cultured human peripheral blood lymphocytes in patients with urinary tract infection. Sister chromatid exchange (SCE), mitotic index (MI) and replicative index (RI) were measured before and after ciprofloxacin therapy. Our results showed that SCE frequency significantly increased after ciprofloxacin therapy (P < 0.001), but MI and RI decreased (P < 0.001). The results of this study suggest that clinical therapy using ciprofloxacin may have a moderate genotoxic potential.


Analysis Of Borrelia Burgdorferi Antibody Seroprevalence In Patients With Behçet´S Disease Using 3 Different Serological Assays, Ergi̇n Ayaşlioğlu, Emel Erkek, Sedat Kaygusuz, Di̇lek Kiliç, Ali̇ İnal, Göksal Keski̇n Jan 2004

Analysis Of Borrelia Burgdorferi Antibody Seroprevalence In Patients With Behçet´S Disease Using 3 Different Serological Assays, Ergi̇n Ayaşlioğlu, Emel Erkek, Sedat Kaygusuz, Di̇lek Kiliç, Ali̇ İnal, Göksal Keski̇n

Turkish Journal of Medical Sciences

Behçet´s disease is a chronic multisystemic inflammatory vasculitis of unknown etiology. Various infectious agents have been implicated as potential triggering factors in the pathogenesis of the disease. The present study was designed to evaluate the seroprevalence of Borrelia burgdorferi antibodies in Turkish patients with Behçet´s disease. For this purpose, 90 consecutive patients with Behçet´s disease and 50 healthy individuals were enrolled into a prospective study. The IgM and IgG antibodies to B. burgdorferi in sera were determined by 3 different serological techniques, namely indirect immunofluorescence assay (IFA), enzyme linked immunosorbent assay (ELISA) and Western blotting (WB). Although there was a …