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Articles 3841 - 3870 of 4871
Full-Text Articles in Medicine and Health Sciences
Cause Of Fever In A Case With End-Stage Renal Disease: Splenic Marginal Zone Lymphoma, Ramazan Çeti̇nkaya, İlhami̇ Ki̇ki̇, Abdullah Uyanik, Mustafa Keleş, Bülent Aydinli, Fazli Erdoğan, Nesri̇n Gürsan, Abdul Meci̇t Kantarci
Cause Of Fever In A Case With End-Stage Renal Disease: Splenic Marginal Zone Lymphoma, Ramazan Çeti̇nkaya, İlhami̇ Ki̇ki̇, Abdullah Uyanik, Mustafa Keleş, Bülent Aydinli, Fazli Erdoğan, Nesri̇n Gürsan, Abdul Meci̇t Kantarci
Turkish Journal of Medical Sciences
Splenic marginal zone lymphomas (SMZL) are rare tumors arising from B-cells, accounting for approximately 1% of all lymphomas. An accompanying lymphoma is uncommon in patients who have chronic renal failure and undergo hemodialysis. We present herein a 35-year-old male hemodialysis patient admitted with fever, abdominal pain, and splenomegaly, diagnosed with SMZL. In our investigations in the English literature, we did not observe any SMZL case among hemodialysis patients. Fever may emerge due to different causes in chronic hemodialysis patients, primarily infections. In hemodialysis patients presenting with fever, lymphoma and other malignant diseases should be considered.
Oropharyngeal Anthrax, Abdullah Taş, Recep Yağiz, Şaban Gürcan, Deni̇z Karaoğlu
Oropharyngeal Anthrax, Abdullah Taş, Recep Yağiz, Şaban Gürcan, Deni̇z Karaoğlu
Turkish Journal of Medical Sciences
Aims: To report a rare case of oropharyngeal anthrax. Materials and Methods: A case report of oropharyngeal anthrax is presented together with the related world literature. Results: A 70-year-old female patient with respiratory distress and extensive swelling of neck, soft palate and uvula is presented. There was ecchymosis on the neck circumferentially. Bacillus anthracis grew in the blood culture. The patient died of toxemia and sepsis. Conclusions: Oropharyngeal anthrax is the least common form of anthrax. This acute illness should be added to the differential diagnosis of inflammatory lesion of the oropharynx with extensive neck swelling. Successful diagnosis of anthrax …
An Unusual Cause Of Dysphagia: Hypopharyngeal Inflammatory Pseudotumor, Baran Acar, Mehmet Ali̇ Babademez, Hayri̇ye Karabulut, Selahatti̇n Genç, R. Murat Karaşen
An Unusual Cause Of Dysphagia: Hypopharyngeal Inflammatory Pseudotumor, Baran Acar, Mehmet Ali̇ Babademez, Hayri̇ye Karabulut, Selahatti̇n Genç, R. Murat Karaşen
Turkish Journal of Medical Sciences
Inflammatory pseudotumor (IP) is a rare pseudoneoplastic and lymphoproliferative disorder. The etiology of IP is still unclear. A 46-year-old male patient presented with a six-month history of dysphagia and diplophonia. Endoscopic examination of the larynx and hypopharynx revealed a 15 x 20 mm smooth-surfaced mass involving the right side of the hypopharynx. Computerized tomography (CT) scans of the neck showed a mass 3 cm in diameter at the level of the hyoid bone. The mass obliterated the pharyngeal lumen. Pathology after incisional biopsy was consistent with pseudotumor. The mass regressed dramatically after corticosteroid treatment and afterwards the patient underwent surgical …
Forensic Emergency Medicine - Six-Year Experience Of 13823 Cases In A University Emergency Department, Ahmet Demi̇rcan, Ayfer Keleş, Nesli̇han Gürbüz, Fi̇kret Bi̇ldi̇k, Şahender Gülbi̇n Aygencel, Nuretti̇n Özgür Doğan, Okşan Deri̇nöz, Taner Akar
Forensic Emergency Medicine - Six-Year Experience Of 13823 Cases In A University Emergency Department, Ahmet Demi̇rcan, Ayfer Keleş, Nesli̇han Gürbüz, Fi̇kret Bi̇ldi̇k, Şahender Gülbi̇n Aygencel, Nuretti̇n Özgür Doğan, Okşan Deri̇nöz, Taner Akar
Turkish Journal of Medical Sciences
Aims: Clinical forensic medicine deals with cases involving both the legal and medical aspects of patient care, such as motor vehicle trauma or poisoning. In this study, we aimed to draw attention to the forensic issues by retrospective investigation of 13823 emergency cases and to share our experiences on this topic. Materials and Methods: This retrospective study was conducted in a university Emergency Department (ED) in Ankara, Turkey. The data were collected from official hospital police sheets. Results: Between 2000 and 2005, 13823 legal cases (3.66% of all ED patients) were examined, and 58.23% of them were male. The mean …
Serum Dehydroepiandrosterone Sulfate Usage For Early Detection Of Prostate Cancer In Men With Serum Prostate Specific Antigen Level Between 2.5 And 4.0 Ng/Ml: A Pilot Study, Yilmaz Aslan, Ümi̇t Tekdoğan, Altuğ Tuncel, Meti̇n Burçi̇n Uzun, Erdem Karabulut, Ali̇ Atan
Serum Dehydroepiandrosterone Sulfate Usage For Early Detection Of Prostate Cancer In Men With Serum Prostate Specific Antigen Level Between 2.5 And 4.0 Ng/Ml: A Pilot Study, Yilmaz Aslan, Ümi̇t Tekdoğan, Altuğ Tuncel, Meti̇n Burçi̇n Uzun, Erdem Karabulut, Ali̇ Atan
Turkish Journal of Medical Sciences
Aims: We prospectively evaluated the diagnostic value of serum prostate specific antigen (PSA)-based diagnostic parameters and serum dehydroepiandrosterone sulfate (DHEAS) level for early detection of prostate cancer in patients with serum PSA level between 2.5 and 4 ng/ml. Materials and Methods: This study included 83 consecutive men with serum PSA levels between 2.5 and 4.0 ng/ml. All patients underwent transrectal ultrasound-guided prostate needle biopsy. Total PSA level, free/total PSA ratio, PSA density of the total volume (PSAD-TV), PSA density of the transition zone (PSAD-TZ), and serum DHEAS values were determined. Results: Seventy-four patients (89.2%) had histopathologically confirmed benign prostatic hyperplasia …
Assessment Of Mental Health Of University Students With Ghq-12, Sarp Üner, Hi̇lal Özcebe, T. Gökhan Telatar, Sabahat Tezcan
Assessment Of Mental Health Of University Students With Ghq-12, Sarp Üner, Hi̇lal Özcebe, T. Gökhan Telatar, Sabahat Tezcan
Turkish Journal of Medical Sciences
Aims: The aim of this study was to assess the mental health status of university students and the factors affecting their mental health. Materials and Methods: The universe of the study consisted of a total of 8407 students enrolled as first- or third-year students of a university. The study sample was determined by using the ``sampling size where the population in universe is known´´ formula. The study questionnaire was designed to include questions regarding some sociodemographic characteristics and the General Health Questionnaire (GHQ)-12. Data were analyzed by SPSS 15.0, and binary logistic regression forward selection method was used to determine …
The Anesthetic Approach In A Patient With Type I Neurofibromatosis With Multiple Deformities, Nurten İnan, Hülya Başar, Müge Türkoğlu, Handan Güleç, Esma Tezer, Bülent Baltaci
The Anesthetic Approach In A Patient With Type I Neurofibromatosis With Multiple Deformities, Nurten İnan, Hülya Başar, Müge Türkoğlu, Handan Güleç, Esma Tezer, Bülent Baltaci
Turkish Journal of Medical Sciences
von Recklinghausen disease is a type I neurofibromatosis originating from the nervous system. In this syndrome, there is abnormal deposition of neural tissue in the nervous system, endocrine system, visceral structures, and skin. We report the anesthetic management of a 31-year-old female patient with multiple thorax deformities who was diagnosed as von Recklinghausen disease. The patient was admitted to the Plastic and Reconstructive Surgery Department because of a huge subcutaneous neurofibroma on her right upper extremity. General anesthesia was considered a high risk for this patient on the basis of her laboratory results and physical findings. We planned brachial plexus …
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Turkish Journal of Medical Sciences
Although cutaneous tuberculosis is rarely seen in developed countries, it is still commonly seen in developing countries. Tuberculosis verrucosa cutis (TVC) is a form of cutaneous tuberculosis that is caused by direct inoculation of Mycobacterium tuberculosis into the skin through open wounds or abrasions in sensitized individuals and is rarely seen in our country. Scrofuloderma is a form of cutaneous tuberculosis that occurs by direct spread of Mycobacterium tuberculosis from a contiguous structure. Coexistence of TVC and scrofuloderma is extremely rare. A 35-year-old woman presented to our clinic with a lesion on the dorsum of her left hand. Dermatological examination …
Taqi Polymorphism Of The Vitamin-D Receptor Gene And Quality Of Life In Postmenopausal Turkish Women, Savaş Gürsoy, Emi̇n Erdal, Belgi̇n Alaşehi̇rli̇, Ali̇ Aydeni̇z, Nuran Erdal
Taqi Polymorphism Of The Vitamin-D Receptor Gene And Quality Of Life In Postmenopausal Turkish Women, Savaş Gürsoy, Emi̇n Erdal, Belgi̇n Alaşehi̇rli̇, Ali̇ Aydeni̇z, Nuran Erdal
Turkish Journal of Medical Sciences
Aim: We aimed to assess vitamin-D receptor (VDR) gene polymorphism in postmenopausal osteoporotic Turkish women as well as the impact of this on diagnosis, treatment and quality of life. Materials and Methods: Seventy postmenopausal osteoporotic women and 71 postmenopausal healthy women constituted the disease and control groups, respectively. Genomic DNA was extracted from blood of all participants and analyzed for the TaqI gene polymorphism of the VDR gene. The osteoporotic group was taking calcitonin, alendronate, calcitriol and elementary calcium, while the control group was taking only vitamin D and calcium. Quality of life of patients was measured by Nottingham Health …
Effects Of Cypermethrin On Isolated Frog Sciatic Nerve: An Ultrastructural Study, S. Necat Yilmaz, Ülkü Çömelekoğlu, Banu Coşkun, Ebru Balli, Aynur Özge
Effects Of Cypermethrin On Isolated Frog Sciatic Nerve: An Ultrastructural Study, S. Necat Yilmaz, Ülkü Çömelekoğlu, Banu Coşkun, Ebru Balli, Aynur Özge
Turkish Journal of Medical Sciences
Aim: Cypermethrin is a potent representative of the type 2 pyrethroid insecticides. This study aimed to investigate the ultrastructural effects of cypermethrin on isolated frog sciatic nerve. Materials and Methods: 28 Rana ridibunda frogs were chosen and randomly divided into four groups (n = 7). After decapitation, sciatic nerves were isolated. All nerves except the control group were exposed to 2.5 µM cypermethrin in Ringer´s solution for 30 (group 1), 45 (group 2) and 60 (group 3) minutes, respectively. Tissue samples were evaluated by transmission electron microscope. Results: Degeneration in the myelin sheath and axon, decrease in the number of …
Susceptibility Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Urine Isolates To Fosfomycin, Ciprofloxacin, Amikacin And Trimethoprim-Sulfamethoxazole, Hüsnü Pullukçu, Şöhret Aydemi̇r, Meltem Işikgöz Taşbakan, Feri̇ha Çi̇lli̇, Alper Tünger, Sercan Ulusoy
Susceptibility Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Urine Isolates To Fosfomycin, Ciprofloxacin, Amikacin And Trimethoprim-Sulfamethoxazole, Hüsnü Pullukçu, Şöhret Aydemi̇r, Meltem Işikgöz Taşbakan, Feri̇ha Çi̇lli̇, Alper Tünger, Sercan Ulusoy
Turkish Journal of Medical Sciences
Aim: Urinary tract infections (UTIs) caused in particular by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains are related with high morbidity and mortality, and treatment is quite difficult. These infections generally are treated by carbapenems, and their costs are high. We aimed in this study to investigate the susceptibilities of ESBL-producing E. coli strains isolated from urine cultures to fosfomycin, ciprofloxacin, amikacin and trimethoprim-sulfamethoxazole and to determine the general resistance profile in our region of these strains isolated from UTIs. Materials and Methods: Between January 2005-December 2005, ESBL-producing E. coli strains isolated from urine samples sent from various outpatient and inpatient …
Serum Homocysteine Levels In Highway Toll Collectors And The Relationship With Intima-Media Thickness Of The Carotid Artery, Ramazan Memi̇şoğullari, Beşi̇r Erdoğmuş, Hami̇t Hakan Alp, Cahi̇t Bi̇lgi̇n, Peri̇ Meram Arbak, Özlem Yavuz
Serum Homocysteine Levels In Highway Toll Collectors And The Relationship With Intima-Media Thickness Of The Carotid Artery, Ramazan Memi̇şoğullari, Beşi̇r Erdoğmuş, Hami̇t Hakan Alp, Cahi̇t Bi̇lgi̇n, Peri̇ Meram Arbak, Özlem Yavuz
Turkish Journal of Medical Sciences
Aim: A relationship between air pollution and increased intima-media thickness (IMT) has been recently reported, but its etiology is not yet well understood. We aimed to determine whether exposure to exhaust particles, which are important air pollutants, is associated with increased serum homocysteine (Hcy) levels and whether elevated Hcy levels are associated with increased IMT. Materials and Methods: Serum Hcy levels were measured by fluorometric high performance liquid chromatography in 65 male highway toll collectors (HTCs) and 43 healthy male volunteers. IMT was measured with Doppler sonography by an experienced radiologist. Results: Serum Hcy levels (14.5 ± 4.9 mmol/L, P < 0.005) and IMT (0.757 ± 0.18 mm, P < 0.001) were higher in the HTC group than in controls (12.0 ± 2.8 mmol/L and 0.612 ± 0.11 mm, respectively). A positive correlation was found between Hcy level and IMT both in the HTC group (r = 0.36; P < 0.005) and in the control group (r = 0.36; P < 0.05). Conclusions: Exposure to exhaust particles may cause an increase in oxidative stress because of an increase in serum Hcy levels, which consequently may lead to an increase in IMT. Nevertheless, further studies on the subject are needed before drawing a firm conclusion.
Prevalence Of The Metabolic Syndrome In A Rural Turkish Population: Comparison And Concordance Of Two Diagnostic Criteria, Ayfer Gemalmaz, Serpi̇l Aydin, Okay Başak, Güzel Di̇şçi̇gi̇l, Aslihan Karul
Prevalence Of The Metabolic Syndrome In A Rural Turkish Population: Comparison And Concordance Of Two Diagnostic Criteria, Ayfer Gemalmaz, Serpi̇l Aydin, Okay Başak, Güzel Di̇şçi̇gi̇l, Aslihan Karul
Turkish Journal of Medical Sciences
Aim: This study was performed to compare the prevalence of the metabolic syndrome (MES) according to the International Diabetes Federation (IDF) and Adult Treatment Panel III (ATPIII) definitions in a population-based sample and to determine the concordance of the definitions. Materials and Methods: A total of 244 adults aged >=20 years (145 women and 99 men), selected systematically from household registration cards in a rural village in West Anatolia, were analyzed. Kappa test was done to examine the agreement between the definitions. Results: The mean age of the group was 46.9 ± 14.9 years. The prevalence of MES using ATPIII …
Survival Of Salmonella Typhi And Shigella Flexneri In Different Water Samples And At Different Temperatures, M. Hami̇dullah Uyanik, Hali̇l Yazgi, Ahmet Ayyildiz
Survival Of Salmonella Typhi And Shigella Flexneri In Different Water Samples And At Different Temperatures, M. Hami̇dullah Uyanik, Hali̇l Yazgi, Ahmet Ayyildiz
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to evaluate the survival of Salmonella typhi and Shigella flexneri, which have significance for public health, in various aqueous media (distilled water, 0.9% NaCl solution, chlorinated water) and at different temperatures. Materials and Methods: The water samples mentioned above were contaminated with approximately 5 x 10^5 bacteria/ml of S. typhi and S. flexneri, and then stored at 37 ºC, room temperature, in refrigerator (4 to 6 ºC) and in deep freezer (-20 ºC). From the water materials prepared accordingly, cultures were done beginning in the first 24 hours and later every other day for …
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Turkish Journal of Medical Sciences
Mixed medullary-follicular carcinoma is an uncommon tumor of the thyroid. It is characterized by histological and immunohistochemical features of both follicular and parafollicular C cells. We report two female patients, aged 26 and 78 years, with mixed medullary-follicular carcinoma. Histologically, the tumors are composed of follicular carcinoma areas and solid nests of polygonal cells consistent with medullary carcinoma. Immunohistochemically, thyroglobulin and calcitonin positivity was detected. Precise diagnosis of mixed medullary-follicular carcinoma is essential for accurate treatment and follow-up.
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Turkish Journal of Medical Sciences
The septate uterus is the most common form of structural uterine anomalies. A rare developmental variant is a complete septate uterus with cervical duplication and a complete vaginal septum. Experiences with these unique uterine anomalies are limited only to case reports. Although there have been a few families in which members are affected similarly, there are no reports in the literature describing dizygotic twins with the same congenital uterine malformation, as seen in our cases. A 28-year-old woman and her dizygotic twin sister who had spontaneous abortion history were identified in our practice with complete septate uterus, cervical duplication and …
Ear Lobule Flap For Reconstruction Of A Near Total Auricle Defect, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Uğur Çakmak, Tayyar Selçuk, Seli̇m Çelebi̇oğlu
Ear Lobule Flap For Reconstruction Of A Near Total Auricle Defect, Bi̇rol Ci̇velek, Ercan Demi̇rbağ, Uğur Çakmak, Tayyar Selçuk, Seli̇m Çelebi̇oğlu
Turkish Journal of Medical Sciences
A number of surgical procedures can be performed for partial auricular defects occurring due to various causes. The most appropriate reconstruction method should be employed with regard to the defect dimensions and the status of local adjacent tissues. We present a case of near total excision of external ear due to recurrent basal cell carcinoma and the reconstruction of the defect with ear lobule flap.
What Influences Herbal Medicine Use? - Prevalence And Related Factors, Serpi̇l Aydin, Ayfer O. Bozkaya, Mümtaz M. Mazicioğlu, Ayfer Gemalmaz, Ali̇s Özçakir, Ahmet Öztürk
What Influences Herbal Medicine Use? - Prevalence And Related Factors, Serpi̇l Aydin, Ayfer O. Bozkaya, Mümtaz M. Mazicioğlu, Ayfer Gemalmaz, Ali̇s Özçakir, Ahmet Öztürk
Turkish Journal of Medical Sciences
Aims: The use and cost of complementary/alternative medicine (CAM) has been gaining in importance worldwide. Herbal medicine is one of the most commonly used methods. To understand the effectiveness, reliability, and quality of CAM and provide standardization in its analysis, its prevalence and the factors influencing its use must be identified. This study was conducted to identify the prevalence of CAM use and the effective factors in our population. Materials and Methods: A stratified multistage probability sampling design was used in this cross-sectional, population-based study, which was conducted in Aydin. Participants were interviewed face to face by trained interviewers with …
Bilateral Galactocele In A Male Infant, Hakan Döneray, Behzat Özkan, Fazli Erdoğan, Ahmet Bedi̇i̇ Salman
Bilateral Galactocele In A Male Infant, Hakan Döneray, Behzat Özkan, Fazli Erdoğan, Ahmet Bedi̇i̇ Salman
Turkish Journal of Medical Sciences
Temporary breast enlargement may be seen in normal newborn and adolescent boys. Cysts of the breast are uncommon in childhood. Galactocele, defined as an encysted collection of milk products, is an extremely rare cause of breast enlargement in infants and children. We herein report a male infant with bilateral galactocele who was otherwise healthy, and we also review the literature.
Evaluation Of Serological Tests For The Diagnosis Of Visceral Leishmaniasis, Selçuk Kiliç, Ayşegül Taylan Özkan, Cahi̇t Babür, Gönül Tanir, Henk Dfh Schallig
Evaluation Of Serological Tests For The Diagnosis Of Visceral Leishmaniasis, Selçuk Kiliç, Ayşegül Taylan Özkan, Cahi̇t Babür, Gönül Tanir, Henk Dfh Schallig
Turkish Journal of Medical Sciences
Aim: Visceral leishmaniasis (VL) is a zoonosis that affects both animals and man. VL is seen sporadically in the Aegean, Mediterranean, Black Sea and central Anatolian regions of Turkey. The aim of this study was to evaluate serological tests for the diagnosis of VL. Materials and Methods: The performance of two agglutination tests based on freeze-dried whole promastigote Leishmania antigen, i.e. Fast Agglutination Screening Test (FAST) and Direct Agglutination Test (DAT), an Indirect Immunofluorescent Antibody Test (IFAT), and an Enzyme-Linked Immunosorbent Assay (ELISA) using soluble antigen were compared to parasitological diagnosis in the serum specimens of 59 patients with the …
The Impact Of Patient Education On Diabetes Empowerment Scale (Des) And Diabetes Attitude Scale (Das-3) In Patients With Type 2 Diabetes, Nazli Atak, Kenan Köse, Tanju Gürkan
The Impact Of Patient Education On Diabetes Empowerment Scale (Des) And Diabetes Attitude Scale (Das-3) In Patients With Type 2 Diabetes, Nazli Atak, Kenan Köse, Tanju Gürkan
Turkish Journal of Medical Sciences
Aim: This study was conducted to assess the impact of a brief, patient-centered education program on perceived self-efficacy and attitudes towards diabetes of patients with type 2 diabetes. Materials and Methods: A randomized controlled study was designed and conducted to assess the impact of education using the DES (Diabetes Empowerment Scale) and DAS-3 (Diabetes Attitude Questionnaire-3), which were administered using a pre- and post-test design. A patient-centered education program was developed on the basis of the data supplied from patients' responses to a knowledge pre-test and the ´´Teaching Letters`` prepared by the Diabetes Education Study Group (DESG) of the European …
Seckel Syndrome With Spontaneous Chromosomal Instability, Abdulgani̇ Tatar, Zeynep Ocak, Hakan Döneray, Ergi̇n Işik, Ahmet Yeşi̇lyurt, Behzat Özkan, Sitki Öztaş
Seckel Syndrome With Spontaneous Chromosomal Instability, Abdulgani̇ Tatar, Zeynep Ocak, Hakan Döneray, Ergi̇n Işik, Ahmet Yeşi̇lyurt, Behzat Özkan, Sitki Öztaş
Turkish Journal of Medical Sciences
Seckel syndrome is an autosomal recessive disorder characterized by prenatal and postnatal growth retardation, bird-headed face and mild mental retardation. It is a disorder involving the DNA damage-response genes. Failure in the DNA damage response and repair process can cause chromosomal instability. In addition, it is possible that there are several loci responsible for this syndrome, and variety in the molecular pathogenesis is the cause of phenotypic heterogeneity. Three different loci have been reported thus far. The effect of the locus with mutation on phenotype may be used in the subgrouping of Seckel syndrome. We report a case with Seckel …
Cisplatin Causes Oxidation In Rat Liver Tissues: Possible Protective Effects Of Antioxidant Food Supplementation, Aslihan Avci, Recep Çeti̇n, İmge B. Ergüder, Erdi̇nç Devri̇m, Bülent Kiliçoğlu, Özden Çandir, H. Serdar Öztürk, İlker Durak
Cisplatin Causes Oxidation In Rat Liver Tissues: Possible Protective Effects Of Antioxidant Food Supplementation, Aslihan Avci, Recep Çeti̇n, İmge B. Ergüder, Erdi̇nç Devri̇m, Bülent Kiliçoğlu, Özden Çandir, H. Serdar Öztürk, İlker Durak
Turkish Journal of Medical Sciences
Aims: In this study, we aimed to investigate the possible molecular mechanism of cisplatin hepatotoxicity and to establish whether some natural antioxidant foods, namely dried black grape and tomato, may provide protection against cisplatin hepatotoxicity. Materials and Methods: Twenty-eight rats were used throughout the study. Cisplatin was administered intraperitoneally (i.p.) in a single dose (10 mg/kg). Antioxidant food supplementation was started three days before cisplatin treatment. There were 7 animals in each group (control, cisplatin, cisplatin plus dried black grape and cisplatin plus tomato juice). Rats were sacrificed 72 h after the treatment. The livers were removed and prepared for …
The Importance Of Serum Procalcitonin Levels In Patients With Chronic Obstructive Pulmonary Disease Exacerbations, Cantürk Taşçi, Arzu Balkan, Nuri̇ Karadurmuş, Satilmiş İnal, Seli̇m Kiliç, Meti̇n Özkan, Hayati̇ Bi̇lgi̇ç, Kudret Eki̇z
The Importance Of Serum Procalcitonin Levels In Patients With Chronic Obstructive Pulmonary Disease Exacerbations, Cantürk Taşçi, Arzu Balkan, Nuri̇ Karadurmuş, Satilmiş İnal, Seli̇m Kiliç, Meti̇n Özkan, Hayati̇ Bi̇lgi̇ç, Kudret Eki̇z
Turkish Journal of Medical Sciences
Aim: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable, but progressive disease and hospital admissions of patients with COPD are frequently due to acute exacerbations. Acute phase reactants are capable of demonstrating the inflammation; however, they cannot be employed to make a difference between bacterial and nonbacterial causes of the inflammation. Recently, measurement of procalcitonin (PCT) levels appears to be useful in order to minimize this problem. The aim of this study was to examine whether the treatment arrangements based on serum PCT levels in patients presenting with COPD acute exacerbations will be appropriate or not. Materials and …
Different Segregation Of Chromosomes 5 And 7 In Two Generations And Related Phenotypic Findings, Osman Demi̇rhan, Nurdan Tunali, Şeyda Erdoğan, Deni̇z Taştemi̇r, Erdal Tunç
Different Segregation Of Chromosomes 5 And 7 In Two Generations And Related Phenotypic Findings, Osman Demi̇rhan, Nurdan Tunali, Şeyda Erdoğan, Deni̇z Taştemi̇r, Erdal Tunç
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to put forth the clinical consequences of rearrangement between chromosomes 5 and 7 observed in one fetus, one newborn infant (siblings) and their parents. Materials and Methods: We performed chromosomal analysis in one fetus, one newborn (siblings) and their parents, applying standard protocols to fetal blood, amniotic fluid and peripheral blood samples. We performed both prenatal and postnatal karyotyping in the newborn infant. Results: We described rearrangements related to chromosomes 5 and 7 in these individuals. We found that the curetted fetus and newborn infant were carriers of unbalanced and balanced rearrangements, respectively. We …
The Relationship Between Carnitine Levels And Lipid Peroxidation In Glial Brain Tumors, Ni̇lüfer Bayraktar, Hati̇ce Paşaoğlu, Aydin Paşaoğlu, Memduh Kaymaz, Gürsel Bi̇beroğlu, Sevsen Kulaksizoğlu
The Relationship Between Carnitine Levels And Lipid Peroxidation In Glial Brain Tumors, Ni̇lüfer Bayraktar, Hati̇ce Paşaoğlu, Aydin Paşaoğlu, Memduh Kaymaz, Gürsel Bi̇beroğlu, Sevsen Kulaksizoğlu
Turkish Journal of Medical Sciences
Aim: It is assumed that reactive oxygen species and lipid peroxidation cause cell membrane damage and play a role in oncogenesis. Carnitine and acyl esters, which play a role in intracellular short-, medium-, and long-chain fatty acid metabolism, are one of the defense mechanisms against free radical toxicity. It is thought that the protective effects of carnitine are related with its role in lipid metabolism. In our study, we analyzed the relation between malondialdehyde (MDA) and free carnitine, and C2, C3, C4, C5, C6, C8, C10, C12, C14:1, C14, C16:1, C16, C18:1, C18, C20:4 carnitine levels in glial tumors [glioblastoma …
Effects Of Omega-3 On Lipid Peroxidation And Antioxidant Enzymes In Mk-801 Induced Schizophrenic Rat Testis, Bi̇rsen Özyurt, Fi̇kret Erdemi̇r, Beki̇r Suha Parlaktaş, Hüseyi̇n Özyurt, Hasan Erdoğan, Ayten Türkkani Tunç
Effects Of Omega-3 On Lipid Peroxidation And Antioxidant Enzymes In Mk-801 Induced Schizophrenic Rat Testis, Bi̇rsen Özyurt, Fi̇kret Erdemi̇r, Beki̇r Suha Parlaktaş, Hüseyi̇n Özyurt, Hasan Erdoğan, Ayten Türkkani Tunç
Turkish Journal of Medical Sciences
No abstract provided.
Laparoscopic Cystogastrostomy For The Management Of Pancreatic Pseudocysts, Kaya Saribeyoğlu, Sali̇h Pekmezci̇, Ece Kol, Meti̇n Kapan, Hasan Taşçi
Laparoscopic Cystogastrostomy For The Management Of Pancreatic Pseudocysts, Kaya Saribeyoğlu, Sali̇h Pekmezci̇, Ece Kol, Meti̇n Kapan, Hasan Taşçi
Turkish Journal of Medical Sciences
Aims: To assess the value of laparoscopic cystogastrostomy in the treatment of pancreatic pseudocysts. Materials and Methods: Patients who underwent laparoscopic surgery for pancreatic pseudocysts were included in the study. All the cysts were non-resolving, symptomatic and large, as a result of acute pancreatitis. Laparoscopic cystogastrostomies were performed by either anterior transgastric or posterior techniques. Results: From February 2001 to November 2006, seven patients were included into the study. The etiology of pancreatitis was gallstone disease in six cases and hyperlipidemia in one. The mean age was 58.7 years (52-69) and the mean pseudocyst size was 15.1 cm (7-20). Transgastric …
Is The Gök Atlas Sufficiently Reliable For Forensic Age Determination Of Turkish Children?, Bora Büken, Erhan Büken, Alp Alper Şafak, Burhan Yazici, Zerri̇n Erkol, Ati̇lla Mayda
Is The Gök Atlas Sufficiently Reliable For Forensic Age Determination Of Turkish Children?, Bora Büken, Erhan Büken, Alp Alper Şafak, Burhan Yazici, Zerri̇n Erkol, Ati̇lla Mayda
Turkish Journal of Medical Sciences
Aim: We investigated whether the contemporary use of the Gök Atlas method is sufficiently reliable for forensic age estimations of Turkish children. Materials and Methods: Plain radiographs of 248 females and 298 males between 11 and 22 years of age were taken. Paired sample t-tests, Pearson correlation coefficients, and linear regression were used to determine the differences and model the relationships between mean skeletal (bone) age (BA) and mean chronological age (CA), using SPSS 11.5 statistical software. Results: In all cases, the CA and BA scores were significantly different and showed high correlation (P < 0.05). The regression model was significant (P < 0.01). According to age groups, the BA was greater than the CA for all age groups by 0.09-3.10 years for boys and 0.44-3.05 years for girls, and this difference was significant for all age groups >14 years for boys and for …
Effect Of Lactation On Bone Mineral Density Later In Life In Turkish Women, Orhan Aksakal, Hakan Aytan, Sabri̇ Cavkaytar, Ömer Lütfi̇ Tapisiz, Tayfun Güngör, Bülent Özdal, Leyla Mollamahmutoğlu
Effect Of Lactation On Bone Mineral Density Later In Life In Turkish Women, Orhan Aksakal, Hakan Aytan, Sabri̇ Cavkaytar, Ömer Lütfi̇ Tapisiz, Tayfun Güngör, Bülent Özdal, Leyla Mollamahmutoğlu
Turkish Journal of Medical Sciences
Aim: To investigate the probable effect of lactation on bone mineral density (BMD) later in life. Materials and Methods: Eighty-seven premenopausal and 18 postmenopausal Turkish women were classified into four groups according to age. Age, height, weight, menopausal status, age at menopause (in postmenopausal women), years since menopause (in postmenopausal woman), parity and total lactation period were recorded. Lumbar spine BMD (L2-L4) was measured by dual-energy X-ray absorptiometry (DEXA). In each group, correlations of lactation with BMD were investigated using Pearson correlation test, and multiple regression analyses were used to determine the factors associated with BMD. Results: No significant correlation …