Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (110)
- Children (97)
- Oxidative stress (90)
- Inflammation (65)
- Rat (62)
-
- Mortality (59)
- Treatment (57)
- Turkey (57)
- Breast cancer (51)
- Prognosis (51)
- Pregnancy (49)
- Apoptosis (47)
- Prevalence (47)
- Magnetic resonance imaging (46)
- Obesity (46)
- Diabetes mellitus (37)
- Quality of life (36)
- Risk factors (36)
- Diagnosis (34)
- Nitric oxide (32)
- Ultrasonography (32)
- Rheumatoid arthritis (31)
- Epidemiology (30)
- Asthma (29)
- Hypertension (29)
- Reliability (29)
- Child (28)
- Validity (28)
- Depression (26)
- Diabetes (26)
- Publication Year
Articles 3181 - 3210 of 4871
Full-Text Articles in Medicine and Health Sciences
Analysis Of Promoter Methylation Of Dickkopf1 (Dkk1) Gene In Breast Cancer, Muradi̇ye Acar, Tülün Çora, Hati̇ce Toy, Hasan Acar
Analysis Of Promoter Methylation Of Dickkopf1 (Dkk1) Gene In Breast Cancer, Muradi̇ye Acar, Tülün Çora, Hati̇ce Toy, Hasan Acar
Turkish Journal of Medical Sciences
Breast cancer is the most common malignancy in women worldwide. The Dickkopf1 (DKK1) gene product is a potent inhibitor of the Wnt pathway. DKK1 methylation status and its protein expression were examined in normal and cancer tissues of breast cancer patients. Materials and methods: We examined methylation changes in 83 tumor and adjacent normal tissues, and also in 9 normal breast tissues from unaffected women (no breast cancer history) as controls. DKK1 promoter methylation was assessed by methylation-specific polymerase chain reaction. Immunohistochemical staining was used to investigate DKK1 protein expression in the 9 controls and in 70 out of the …
The Role Of Hba1c As A Screening And Diagnostic Test For Diabetes Mellitus In Ankara, Zeynep Gi̇ni̇ş, Gülfer Öztürk, Rana Sirmali, Ali̇ Yalçindağ, Yakup Dülgeroğlu, Tuncay Deli̇başi, Namik Deli̇baş
The Role Of Hba1c As A Screening And Diagnostic Test For Diabetes Mellitus In Ankara, Zeynep Gi̇ni̇ş, Gülfer Öztürk, Rana Sirmali, Ali̇ Yalçindağ, Yakup Dülgeroğlu, Tuncay Deli̇başi, Namik Deli̇baş
Turkish Journal of Medical Sciences
This study investigated the value of HbA1c as a screening and diagnostic test for diabetes mellitus (DM) in high-risk Turkish individuals. Materials and methods: A total of 295 participants were successfully screened. Patients were divided into 4 groups based on their oral glucose tolerance test results, according to criteria put forth by the American Diabetes Association; 120 (40.7%) had normoglycemia, 44 (14.9%) had DM, 62 (21%) had impaired fasting glucose, and 69 (23.4%) had impaired glucose tolerance. Results: With a cut-off value for the diagnosis of DM of 6.1%, HbA1c had a sensitivity of 81.8% and a specificity of 80%, …
Effects Of Lycopene On Plasma Glucose, Insulin Levels, Oxidative Stress, And Body Weights Of Streptozotocin-Induced Diabetic Rats, Muhsi̇n Aydin, Sefa Çeli̇k
Effects Of Lycopene On Plasma Glucose, Insulin Levels, Oxidative Stress, And Body Weights Of Streptozotocin-Induced Diabetic Rats, Muhsi̇n Aydin, Sefa Çeli̇k
Turkish Journal of Medical Sciences
To determine possible therapeutic effects of oral lycopene supplementation on plasma insulin levels, lipid peroxidation, blood glucose levels, and the antioxidant defense system of streptozotocin-induced diabetic rats. Materials and methods: Classical biochemical methods were used to determine plasma malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) levels. Enzyme-linked immunosorbent assay was used to determine plasma insulin levels and reverse transcriptase-polymerase chain reaction was used to determine the levels of brain antioxidant enzymes (SOD, CAT, and GSH-Px). Results: It was found that the diabetes-related increase in blood glucose levels was reduced by supplementation …
Descending Necrotizing Mediastinitis: Increased Mortality Due To Delayed Presentation, Mehmet Muharrem Erol, Ahmet Ural, Hüseyi̇n Melek, Ahmet Sami̇ Bayram, Celal Teki̇nbaş, Cengi̇z Gebi̇teki̇n
Descending Necrotizing Mediastinitis: Increased Mortality Due To Delayed Presentation, Mehmet Muharrem Erol, Ahmet Ural, Hüseyi̇n Melek, Ahmet Sami̇ Bayram, Celal Teki̇nbaş, Cengi̇z Gebi̇teki̇n
Turkish Journal of Medical Sciences
To describe the clinical features of descending necrotizing mediastinitis (DNM) and to outline the diagnostic and therapeutic measures to be taken in its management. Materials and methods: We retrospectively analyzed the data from 13 patients with DNM treated between 2001 and 2012 in 2 tertiary care centers, together with their demographics, diagnostic methods, therapeutic interventions, and clinical outcomes. Results: The patients consisted of 10 males and 3 females, aged from 16 to 72 years (mean age: 44). Odontogenic and tonsillar infections were the probable sources of infection in the majority of cases. Computerized tomography is a crucial imaging modality in …
The Efficacy Of Topical Testosterone Treatment On Preputial Microvessel Density In Distal Hypospadias, Mustafa Çağri Savaş, Şi̇ri̇n Başpinar, Levent Duman, Fatma Ni̇lgün Kapucuoğlu
The Efficacy Of Topical Testosterone Treatment On Preputial Microvessel Density In Distal Hypospadias, Mustafa Çağri Savaş, Şi̇ri̇n Başpinar, Levent Duman, Fatma Ni̇lgün Kapucuoğlu
Turkish Journal of Medical Sciences
To investigate the efficacy of topical testosterone treatment on the microvessel density (MVD) of hypospadiac prepuce. Materials and methods: The prepuces of 20 healthy children undergoing routine circumcision served as the control group, while the prepuces of 20 children undergoing hypospadias repair served as the hypospadias group. The hypospadias group was further divided into 2 equal subgroups (n = 10) as the hypospadias with or without testosterone treatment groups. The meatal locations were coronal and subcoronal in all of the patients with hypospadias. The prepuces were stained by immunohistochemical methods using panendothelial cell antigen CD31 in order to assay their …
Cytological Analysis Of The Oral Cells Of Chronic Renal Failure Patients: A Cytomorphometric Study, Ümmühan Tozoğlu, Mustafa Keleş, Deni̇z Ünal, Abdullah Uyanik
Cytological Analysis Of The Oral Cells Of Chronic Renal Failure Patients: A Cytomorphometric Study, Ümmühan Tozoğlu, Mustafa Keleş, Deni̇z Ünal, Abdullah Uyanik
Turkish Journal of Medical Sciences
The aim of this study was to cytologically analyze the tongue mucosa, buccal mucosa, and floor of the mouth of patients with chronic renal failure and healthy volunteers to determine what cellular changes are caused by uremic diseases. Materials and methods: In order to evaluate cellular changes induced by chronic renal failure, exfoliative cytology was used for the analysis of the tongue mucosa, buccal mucosa, and floor of the mouth of 20 uremic patients with chronic renal failure and 20 healthy volunteers. Smears from each individual were stained using the Papanicolaou method and were analyzed using a stereological method. Results: …
The Relative Frequency Of Odontogenic Tumors In The Black Sea Region Of Turkey: An Analysis Of 86 Cases, Fi̇gen Çi̇zmeci̇ Şenel, Ezher Hamza Dayisoylu, Şafak Ersöz, Nuray Yilmaz Altintaş, Emre Tosun, Cem Üngör, Fati̇h Taşkesen
The Relative Frequency Of Odontogenic Tumors In The Black Sea Region Of Turkey: An Analysis Of 86 Cases, Fi̇gen Çi̇zmeci̇ Şenel, Ezher Hamza Dayisoylu, Şafak Ersöz, Nuray Yilmaz Altintaş, Emre Tosun, Cem Üngör, Fati̇h Taşkesen
Turkish Journal of Medical Sciences
To determine the relative frequency and distribution of different types of odontogenic tumors in southeastern Europe, focusing on the Black Sea region of Turkey. Materials and methods: In total 1165 oromaxillofacial biopsy records were evaluated for histologic diagnosis of odontogenic tumors over a 7-year period from patients referred to the Department of Oral and Maxillofacial Surgery and Department of Pathology, Karadeniz Technical University, Faculty of Dentistry and Medicine, Trabzon, Turkey. Results: A total of 86 odontogenic tumors were reported. Malignant transformation only occurred in 6 cases (6.8%), while the others were benign (93.2%). Odontoma was the most common odontogenic tumor …
Nutritional Assessment Via Anthropometric And Biochemical Measurements With Stable Copd, Mehmet Meral, Ömer Araz, Eli̇f Yilmazel Uçar, Nusret Yilmaz, Ni̇hal Arzu Mi̇ri̇ci̇
Nutritional Assessment Via Anthropometric And Biochemical Measurements With Stable Copd, Mehmet Meral, Ömer Araz, Eli̇f Yilmazel Uçar, Nusret Yilmaz, Ni̇hal Arzu Mi̇ri̇ci̇
Turkish Journal of Medical Sciences
Nutritional assessment is important for the management of chronic obstructive pulmonary disease (COPD). This study aims at investigating the relation between the anthropometric and biochemical parameters for nutritional assessment with pulmonary function tests in COPD. Materials and methods: This is a prospective, cross-sectional study. Thirty-nine patients with stable COPD were enrolled the study. We evaluated the anthropometric [body mass index (BMI), skinfold thickness (SFT), and arm muscle circumference (AMC)], biochemical [serum total protein, albumin, transferrin, and blood urea nitrogen (BUN)], and spirometric [forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and FEV1/FVC] measurements, as well as …
Can We Predict The Duration Of Respiratory Support In Transient Tachypnea Of The Newborn?, Osman Özteki̇n, Sali̇h Kalay, Gönül Tezel, Mustafa Akçakuş, Ni̇hal Oygür
Can We Predict The Duration Of Respiratory Support In Transient Tachypnea Of The Newborn?, Osman Özteki̇n, Sali̇h Kalay, Gönül Tezel, Mustafa Akçakuş, Ni̇hal Oygür
Turkish Journal of Medical Sciences
To assess arterial blood gas values and respiratory rates during transient tachypnea of the newborn detected in the first hour of postnatal life, and to investigate whether any of these parameters can be a good predictor of the duration of respiratory support. Materials and methods: Data were collected from the charts of newborns with a gestation of >=37 weeks born in our hospital and admitted to our neonatal intensive care unit with a diagnosis of transient tachypnea of the newborn between January 2007 and December 2009. Patients with respiratory support of >=5 days were accepted as group A and those …
An Indispensable Toxin Known For 2500 Years: Victims Of Mad Honey, Ayşe Semra Demi̇r Akca, Fati̇h Ozan Kahveci̇
An Indispensable Toxin Known For 2500 Years: Victims Of Mad Honey, Ayşe Semra Demi̇r Akca, Fati̇h Ozan Kahveci̇
Turkish Journal of Medical Sciences
Mad honey (bitter honey) is a local name for a particular type of honey used in alternative medicine to treat gastric pain, bowel disorders, and hypertension, and as a sexual stimulant in the Black Sea coastal region of Turkey. Grayonotoxin behaves like cholinergic agents and has dosage dependent adverse effects on the cardiovascular system including bradycardia, atrioventricular block (AVB), and arterial hypotension. In this manuscript, we report 37 cases of mad honey intoxication from the western Black Sea region. Materials and methods: This was a retrospective case series of 37 patients who were admitted to the emergency department of a …
Primary Anorectal Malignant Melanoma: Rare But Highly Lethal Malignancy, Özlem Sönmez, Ümmügül Üyetürk, Kaan Helvaci, İbrahi̇m Türker, Fahri̇ye Tuğba Köş, Lütfi̇ Doğan, Burçi̇n Budakoğlu, Ülkü Yalçintaş Arslan, Ömür Berna Çakmak Öksüzoğlu
Primary Anorectal Malignant Melanoma: Rare But Highly Lethal Malignancy, Özlem Sönmez, Ümmügül Üyetürk, Kaan Helvaci, İbrahi̇m Türker, Fahri̇ye Tuğba Köş, Lütfi̇ Doğan, Burçi̇n Budakoğlu, Ülkü Yalçintaş Arslan, Ömür Berna Çakmak Öksüzoğlu
Turkish Journal of Medical Sciences
Primary anorectal malignant melanoma (MM) is a rare but highly lethal malignancy. The aim of this study was to present an overview of the clinical features and treatment strategies in patients with anorectal MM. Materials and methods: Nine patients who were diagnosed with anorectal MM between 1998 and 2010 were reviewed retrospectively. Results: The median age of the patients was 51 years (range: 28-75). The sex ratio of male to female was 1:2. The main presenting symptom was rectal bleeding. At the time of diagnosis, 1 patient was stage IV and 8 patients were stage III. All of the patients …
Effect Of Intravitreal Octreotide Acetate Injection On Retinal Neovascularization, Morphology, And Apoptotic Cell Death In An Oxygen-Induced Retinopathy Mouse Model, Fatma Seli̇n Kaya, İmren Akkoyun, Asuman Ni̇han Haberal Reyhan, Atti̇la Dağdevi̇ren, Gürsel Yilmaz, Si̇bel Oto, Yonca Akova
Effect Of Intravitreal Octreotide Acetate Injection On Retinal Neovascularization, Morphology, And Apoptotic Cell Death In An Oxygen-Induced Retinopathy Mouse Model, Fatma Seli̇n Kaya, İmren Akkoyun, Asuman Ni̇han Haberal Reyhan, Atti̇la Dağdevi̇ren, Gürsel Yilmaz, Si̇bel Oto, Yonca Akova
Turkish Journal of Medical Sciences
To investigate the effect of octreotide acetate on neovascularization, retinal structures, and apoptotic cell death in an oxygen-induced retinopathy (OIR) mouse model. Materials and methods: A total of 26 C57BL/6J mice were exposed to 75 ± 2% oxygen from postnatal day 7 to 12. On day 12, 12 mice (group C) were injected with 0.1 µg intravitreal octreotide acetate (IVOA) and 14 mice (group D) were injected with 0.05 µg IVOA, in the right eye. The contralateral eyes were injected with 1 µL isotonic saline (control group, group B). Four mice were used as negative controls (group A). Neovascularization was …
Tissue Damage In Abdominal Hysterectomy Performed With A Vessel Sealing System, Ilgin Türkçüoğlu, Ayşe Kafkasli, Çağdaş Doğan, Emrullah Tanrikut
Tissue Damage In Abdominal Hysterectomy Performed With A Vessel Sealing System, Ilgin Türkçüoğlu, Ayşe Kafkasli, Çağdaş Doğan, Emrullah Tanrikut
Turkish Journal of Medical Sciences
To compare the tissue damage, operation times, blood loss, short-term postoperative complication rates, and hospitalization durations of abdominal hysterectomies performed due to benign gynecological conditions using the LigaSure vessel sealing system (LVSS) and conventional suture ligation. Materials and methods: Patients were prospectively enrolled in LVSS (TAH-L group, 22 cases) and suture ligation (TAH-S group, 31 cases) groups. Anesthesia time, operation time, intraoperative blood loss, intraoperative and short-term postoperative complications, and hospitalization durations were compared between the groups. Tissue damage was assessed by comparing changes in C-reactive protein, creatine phosphokinase levels, and white blood cell counts on preoperative and postoperative days …
Effect Of Ovulation Induction On Qt Dispersion In Electrocardiography, Ayla Üçkuyu, Fai̇ka Ceylan Çi̇ftçi̇, Özgür Çi̇ftçi̇, Emel Ebru Özçi̇men, Erzat Toprak, Erdem Turhan
Effect Of Ovulation Induction On Qt Dispersion In Electrocardiography, Ayla Üçkuyu, Fai̇ka Ceylan Çi̇ftçi̇, Özgür Çi̇ftçi̇, Emel Ebru Özçi̇men, Erzat Toprak, Erdem Turhan
Turkish Journal of Medical Sciences
To investigate whether ovulation induction resulting in supra-physiological concentration range of ovarian hormones has an effect on interlead ventricular depolarization heterogeneity via QT dispersion measurements. Estrogens influence the duration of cardiac repolarization but there is no significant change in the QT interval duration within the range of physiological estradiol variations. Materials and methods: Included in the study were 40 subjects, in whom ovulation induction was planned, and 20 volunteers. During the study, a 12-lead electrocardiogram of each woman was carried out 3 times: for the first time on day 2-3 of the menstrual cycle (menstrual day), for the second time …
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Turkish Journal of Medical Sciences
Electrical injuries are still responsible for significant morbidity and mortality; however, they are generally preventable with simple safety measures. This study Abstracts to determine the general features of electrical fatalities, and to draw attention of health professionals towards such preventable deaths. Materials and methods: A retrospective evaluation of records of electrocution-related deaths in Ankara, Turkey, was conducted over 11 years (1998-2008). Results: Out of 12,263 autopsy cases, 100 (0.8%) were secondary to electrocution. Most of the victims were male (n = 94; 94%) while only 6 were female. Victims’ age ranged from 1 year to 76 years, with a mean …
A New Anthropometric Measurement Of Penile Length And Its Relation To Second And Fourth Digital Lengths, Mürsel Davarci, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Yusuf Seli̇m Kaya, Ebru Turhan, Murat Tutanç, Yunus Doğramaci, Mevlana Derya Balbay
A New Anthropometric Measurement Of Penile Length And Its Relation To Second And Fourth Digital Lengths, Mürsel Davarci, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Yusuf Seli̇m Kaya, Ebru Turhan, Murat Tutanç, Yunus Doğramaci, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
The development of digits is under the control of Hox genes, which also control the differentiation of the urogenital system. In the present study we evaluated the association between penile length and lengths of the second and fourth digits. Materials and methods: In this study, 1028 Turkish male primary school children from the Eastern Mediterranean Region of Turkey were included. Weight and height measurements were obtained in order to calculate the body mass index (BMI). Flaccid and stretched length of the penis was measured. The lengths of the second and fourth digits of the right hands were measured. Statistical analyses …
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Turkish Journal of Medical Sciences
Aim: Ileosigmoid knotting (ISK) is a rare event in pregnancy. This study reviewed the clinical outcomes of 3 pregnant patients with ISK and compared the characteristics of these pregnant women with 16 nonpregnant women. Materials and methods: The clinical records were reviewed retrospectively. Results: Three pregnant patients accounted for 4.2% of 72 total ISK patients and 15.8% of 19 female ISK patients. The ages of the patients were 35, 38, and 31 years (mean: 34.7 years). All of the patients were multiparous. Two patients (66.7%) were in the 3rd trimester and 1 (33.3%) was in the 2nd trimester. The mean …
The Effect Of Knk437, A Heat Shock Protein Inhibitor, On Angiogenesis Of Endothelial Cells, Emel Şahi̇n, Mehmet Şahi̇n, Saadet Gümüşlü
The Effect Of Knk437, A Heat Shock Protein Inhibitor, On Angiogenesis Of Endothelial Cells, Emel Şahi̇n, Mehmet Şahi̇n, Saadet Gümüşlü
Turkish Journal of Medical Sciences
Aim: Hyperthermia is an effective therapy for cancer and tumor angiogenesis. However, the development of thermotolerance is an important problem. We aimed to investigate the effects of KNK437 and quercetin on angiogenesis and thermotolerance in endothelial cells (ECs). Materials and methods: ECs were grown in EGM-2 medium. ECs were preincubated with KNK437 or quercetin and then treated with single and fractionated hyperthermia. Tube formation assay on Matrigel Matrix was performed in these cells to investigate angiogenesis. Results: Tube formation was suppressed in cells that were treated with KNK437 and quercetin at 37 °C. Single hyperthermia (45 °C for 1 h) …
Effects Of Neoadjuvant Chemotherapy On Pathological Parameters And Survival In Patients Undergoing Radical Cystectomy For Muscle-Invasive Bladder Cancer, Alper Çağlayan, Zi̇ya Akbulut, Ali̇ Fuat Atmaca, Serkan Altinova, Meti̇n Kiliç, Mevlana Derya Balbay
Effects Of Neoadjuvant Chemotherapy On Pathological Parameters And Survival In Patients Undergoing Radical Cystectomy For Muscle-Invasive Bladder Cancer, Alper Çağlayan, Zi̇ya Akbulut, Ali̇ Fuat Atmaca, Serkan Altinova, Meti̇n Kiliç, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
Aim: To evaluate the effect of neoadjuvant chemotherapy on tumor pathology and patient survival in patients with muscle-invasive bladder cancer undergoing radical cystectomy. Neoadjuvant chemotherapy is believed to prevent micrometastasis and provide pathological downstaging. Materials and methods: Between June 2004 and March 2009, 74 patients with muscle-invasive bladder cancer were treated with radical cystectomy. Patients fit to receive chemotherapy were administered systemic chemotherapy of methotrexate, vinblastine, Adriamycin, and cisplatin (MVAC); gemcitabine and cisplatin (GC); or carboplatin and gemcitabine (CG). Patients in Group 1 (n = 36) did not receive any chemotherapy, while the remaining 38 patients in Group 2 did …
The Impact Of Nephrometry Score On Partial Nephrectomy Rates And Survival, Ali̇ Barbaros Başeski̇oğlu, Yunus Sai̇m Cavi̇t Can, Aydin Yeni̇lmez, Coşkun Kaya
The Impact Of Nephrometry Score On Partial Nephrectomy Rates And Survival, Ali̇ Barbaros Başeski̇oğlu, Yunus Sai̇m Cavi̇t Can, Aydin Yeni̇lmez, Coşkun Kaya
Turkish Journal of Medical Sciences
Aim: To evaluate the utility of the nephrometry score (NS) and its effects on survival using our experiences with renal tumor data. Materials and methods: Data from 220 patients who underwent renal tumor surgery between 2002 and 2008 were analyzed retrospectively. The exclusion criteria were lack of preoperative tomography films or pathological data and loss of patients for follow-up. Preoperative computed tomography of the patients was evaluated according to the R.E.N.A.L. NS system at www.nephrometry.com, and low, moderate, and high complexity groups were compared. A cut-off point of 8 for the NS was determined and patients were grouped. Kaplan-Meier and …
The Role Of Quantitative D-Dimer Levels In The Follow-Up And Differential Diagnosis Of Pulmonary Thromboembolism And Community-Acquired Pneumonia, Ayhan Varol, Nurdan Köktürk, Hati̇ce Kiliç, Müge Aydoğdu, Numan Nadi̇r Eki̇m
The Role Of Quantitative D-Dimer Levels In The Follow-Up And Differential Diagnosis Of Pulmonary Thromboembolism And Community-Acquired Pneumonia, Ayhan Varol, Nurdan Köktürk, Hati̇ce Kiliç, Müge Aydoğdu, Numan Nadi̇r Eki̇m
Turkish Journal of Medical Sciences
Aim: To identify the quantitative D-dimer levels in pulmonary thromboembolism (PTE) and hospitalized-community acquired pneumonia (CAP) patients, and to determine the alteration of D-dimer levels with anticoagulant or antibacterial therapy. It is not well known that the quantitative analysis of D-dimer has a role in the differential diagnosis of PTE from other diseases. Materials and methods: Serum D-dimer levels were measured and compared prospectively with a latex-enhanced immunoturbidimetric method at admission, before initiating any antibiotic or anticoagulant therapy and then at days 3, 10, and 30 of treatment in PTE and CAP patients. Results: A total of 80 patients (45 …
Effect Of Cycloplegia On Refractive Errors Measured With Three Different Refractometers In School-Age Children, Ceyhun Arici, Adem Türk, Soner Keski̇n, Osman Meli̇h Ceylan, Fati̇h Mehmet Mutlu, Hali̇l İbrahi̇m Altinsoy
Effect Of Cycloplegia On Refractive Errors Measured With Three Different Refractometers In School-Age Children, Ceyhun Arici, Adem Türk, Soner Keski̇n, Osman Meli̇h Ceylan, Fati̇h Mehmet Mutlu, Hali̇l İbrahi̇m Altinsoy
Turkish Journal of Medical Sciences
Aim: To compare 3 different refractometers with and without cycloplegia and to examine whether the photorefractometer necessitates cycloplegia in the measurement of refractive errors. Materials and methods: Included in the study were 62 eyes of 31 pediatric patients. The refractive errors of all of the eyes were measured with and without cycloplegia using a table-top autorefractometer (Potec PRK-6000), hand-held autorefractometer (Nidek ARK-30), and photorefractometer (Plusoptix S08), respectively. The spherical power, cylindrical power, cylindrical axis, spherical equivalent, and interpupillary distance values obtained were statistically compared. Results: The average age of the patients was 10.03 ± 2.79 years. There were statistically significant …
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
Turkish Journal of Medical Sciences
Aim: To study the combination treatment consisting of half-dose verteporfin photodynamic therapy (PDT) and an intravitreal injection of ranibizumab as a potential treatment for patients with chronic central serous chorioretinopathy (CSC). Materials and methods: Six eyes of 6 patients were studied with fundus examination, fluorescein angiography, and optical coherence tomography to diagnose the maculopathy, monitor the detachments, and localize the choroidal hyperpermeability of the disorder. Half-dose verteporfin PDT was applied to areas of choroidal hyperpermeability and, the following day, 0.5 mg/0.05 mL ranibizumab was injected intravitreally. The patients were observed to determine the anatomic and functional outcomes. Results: The combination …
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Turkish Journal of Medical Sciences
Aim: To investigate the histology and function of the kidney in mice exposed to different concentrations of phenol through the gavage method for 10 consecutive days. Materials and methods: Forty female BALB/c mice were selected and randomly divided into 1 control group and 3 experimental groups. The control group was administered distilled water through the gavage method, while the experimental groups received daily doses of 80, 180, and 320 mg/kg of phenol, respectively. After 10 days, blood samples were collected and the sera were analyzed biochemically. Renal tissue samples were also taken and histopathological changes of the kidneys were examined …
Effects Of Depression And Life Factors On Social Network Score In Elderly People In Çankaya, Ankara, Meti̇n Canbal, İrfan Şencan, Ayfer Şahi̇n, Şeyda Kunt, Umut Yücel Çavuş, Oğuz Teki̇n
Effects Of Depression And Life Factors On Social Network Score In Elderly People In Çankaya, Ankara, Meti̇n Canbal, İrfan Şencan, Ayfer Şahi̇n, Şeyda Kunt, Umut Yücel Çavuş, Oğuz Teki̇n
Turkish Journal of Medical Sciences
Aim: Social interaction is an important factor in the physical and mental health of seniors. This study was performed in order to evaluate the effects of depression and life factors on the social networking scores of elderly people. Materials and methods: Tests for the Lubben Social Network Scale (LSNS) and Geriatric Depression Scale (GDS) were given to 116 elderly people (>=60 years) in the Çankaya area of Ankara between March and May of 2010. The effects of life factors and GDS scores on LSNS scores were explored. Results: Among the study group, 46.5% of the individuals were male and …
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Turkish Journal of Medical Sciences
Aim: To investigate the effect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fibers in the adult rat offspring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. The saphenous nerve in the adult offspring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of A\alpha\beta-, A\delta-, and C-fibers were examined. Results: Prenatal exposure to CS induced significant reduction (P < 0.005) in the peak amplitude of CAPs of A\alpha\beta- and A\delta-fibers. The conduction velocity of A\alpha\beta-fibers and C-fibers was significantly (P < 0.025-0.05) increased after prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fibers in the rat saphenous nerve.
Plasma Levels Of Il-6 And Tnf-\Alpha In Patients With Esophageal Cancer, Yener Aydin, İbrahi̇m Kaplan, Yusuf Bi̇len, Çağlar Bulut, Fatma Genç, Ati̇la Türkyilmaz, Ati̇la Eroğlu
Plasma Levels Of Il-6 And Tnf-\Alpha In Patients With Esophageal Cancer, Yener Aydin, İbrahi̇m Kaplan, Yusuf Bi̇len, Çağlar Bulut, Fatma Genç, Ati̇la Türkyilmaz, Ati̇la Eroğlu
Turkish Journal of Medical Sciences
Cytokines are multifunctional polypeptides synthesized in various cell types. Interleukin-6 (IL-6) and tumor necrosis factor-\alpha (TNF-\alpha) are cytokines that have important roles in cancer pathogenesis. In this study, we investigated the plasma levels of IL-6 and TNF-\alpha in patients with esophageal cancer. Materials and methods: Forty-three esophageal cancer patients (24 females and 19 males) who were newly diagnosed and had not yet undergone operation participated in the study. The patients' average age was 61.03 ± 12.4 years. The control group, on the other hand, comprised 43 healthy individuals (22 males and 21 females) with an average age of 56 ± …
Ciprofloxacin Versus Levofloxacin In Avoidance Of Prostate Biopsy In Patients With Isolated Psa Elevation: A Prospective Randomized Study, Doğan Ünal, Aki̇f Koç, Ömer Faruk Karataş, Ersi̇n Çi̇mentepe
Ciprofloxacin Versus Levofloxacin In Avoidance Of Prostate Biopsy In Patients With Isolated Psa Elevation: A Prospective Randomized Study, Doğan Ünal, Aki̇f Koç, Ömer Faruk Karataş, Ersi̇n Çi̇mentepe
Turkish Journal of Medical Sciences
The efficiencies of ciprofloxacin and levofloxacin on prostate-specific antigen (PSA) elevation were compared in terms of avoidance of prostate biopsy in this study. Materials and methods: Included in the study were 43 men with PSA levels of >=3.5 ng/mL. They were randomized into either ciprofloxacin or levofloxacin groups for a 3-week course. PSA and free PSA levels were measured before and after the antibiotherapy. The patients in whom PSA remained >=3.5 ng/mL after therapy underwent biopsy. Results: The average age of the men was 64.44 years (standard deviation: 9.54). Following antibiotics, 76.7% of the patients showed a reduction in PSA …
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Turkish Journal of Medical Sciences
To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin resistance (IR) in middle-aged obese women. Materials and methods: The study was designed as a case-control study. The study group included middle-aged obese women and the control group included aged-matched lean women. Weight, height, and hip and waist circumferences were measured. Biochemical parameters such as fasting and postprandial glucose, vitamin B12 and folic acid levels, and lipid profiles were assayed. Results: Enrolled in the study were 116 middle-aged obese and 103 aged-matched healthy lean women. The vitamin B12 level of the obese women was significantly …
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Turkish Journal of Medical Sciences
Since brucellosis has been called a chronic illness and treatment of patients infected with this bacterium has not been successful, the present study aim ed to evaluate the effects of several medicinal plant extracts on clinical Brucella strains. Materials and methods: First, Brucella strains were isolated from brucellosis patients. Then an antibiotic resistance assay was performed for these strains, while the antibacterial activity of the above-mentioned extracts was evaluated. Results: After performing accurate evaluations, the obtained results showed that all of the isolated Brucella strains were sensitive to tetracycline, doxycycline, and gentamicin, and the rates of antibiotic resistance to rifampin …