Other Medicine and Health Sciences Commons^™

Transcriptional And Post-Transcriptional Regulation Of Nrf2 In The Heart By The Deubiquitinase Cyld, Bryan J. Mathis

Theses and Dissertations

The cylindromatosis (CYLD) is a K63-linked deubiquitinase (DUB) that has been linked to the regulation of multiple physiological or pathological processes, such as neural development, inflammation and fibrosis. However, a novel paradigm for CYLD has been recently postulated; namely that of CYLD as a mediator of cardiac disease. Nuclear factor, erythroid-2 related factor 2 (Nrf2), a master antioxidant transcription factor, has been shown to suppress cardiac pathological remodeling and dysfunction via downregulation of reactive oxygen species formation (ROS). It is normally regulated by Kelch-like ECH associated protein 1 (Keap1). However, the regulatory link between CYLD and Nrf2 in the diseased …

Responding To Their Voice: The Needs Of Postsecondary Students With Intellectual And/Or Developmental Disability, Lucretia A. Berg

Ed.D. Dissertations in Practice

Young adults with intellectual and/or developmental disabilities (IDD) enter postsecondary education (PSE) at increasing rates. Many continue to demonstrate persisting adaptive behavior needs that impede academic and employment outcomes. This qualitative case study explored one Northwest PSE program educating students with IDD regarding persisting adaptive behavior needs and whether the needs fell under the purview of occupational therapy (OT). It was the researcher’s assumption that gaining an understanding of student needs would provide cognizance of potential OT services. Thirty-two participants were recruited through both purposive and snowball sampling including: administrators; instructors; related services providers; parents or guardians; and students. In …

Psychological And Psychiatric Comorbidities Associated With Tinnitus: A Systematic Review, Shanna Hymowitz

Dissertations, Theses, and Capstone Projects

The purpose of this systematic literature review was to examine the current literature evidence pertaining to the relationship between tinnitus and psychological and psychiatric comorbidities. Literature was found discussing the prevalence of tinnitus with psychological and psychiatric comorbidities, differences in self-reports, and whether the perception of tinnitus is aided with the use of psychological counseling and psychotropic medications. Relative search strings applied to Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline Complete, and PubMed identified studies to be included in this review. (Will put total amount of studies found once collected). An assessment of all research literature found …

Commencement Program 2016, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2016 Events of Commencement

5 | The Academic Procession

7 | Significance of Academic Regalia

9 | The Good Samaritan

10 | University History Highlights

12 | Loma Linda University Song - "Healing Love"

13 | The Speakers

21 | The University Honorees

36 | The School Honorees

56 | The President's Award Recipients

66 | The Program

• School of Medicine, 67
• School of Pharmacy, 90
• School of Dentistry, 98
• School of Allied Health Professions - Allied Health Studies, Cardiopulmonary Sciences, Clinical Laboratory Science, Health Informatics and Information Management, Nutrition and …

Today - June 2016, Loma Linda University Health

TODAY

Inside this issue:

-- Two weekends of commencement ceremonies add more than 1,500 new alumni and recognize honorees
-- Loma Linda University and Siemens' PETNET Solutions, Inc. announce PET production and research facility
-- Commencement 2016 photo memories (pictorial)
-- Becker's Hospital Review names senior vice president of finance among '150 hospital and health system CFOs to know in 2016'
-- Reading day camp to take place in July
-- Another Emmy win for advancement films
-- Employees line up to sign banners of support for two Florida hospitals in the aftermath of tragic shootings
-- New patient parking structure …

Bulking Up Or Bulging Over: Motivating Physical Activity Through Framing, Lauren Crupnick

Honors Theses

Motivating people to perform physical activities can be a challenging task. One possible avenue is through the use of framing of exercise-related imagery and messages. Gain-frame imagery demonstrates the benefits of performing an activity, whereas loss-frame demonstrates the risks of not taking action on something (Tversky & Kahneman, 1981). With social media as a prevalent platform for exercise tips and tricks, it is possible that the way in which such imagery is framed in advertisements, blogs, and apps could be hindering or helping followers get closer to their physical activity goals. I hypothesized that gain-framed imagery motivates participants to have …

Practice Of Travel Health For Pharmacists, Jeff Goad, Victoria Dudas, Tania Gregorian, Karl Hess

Jeff Goad

No abstract provided.

The Impact Of Alzheimer’S Disease In An Aging Rural Population, Lynne J. Goebel, Vivian M. Minkemeyer, Courtney Wellman

Lynne J. Goebel

West Virginia already has a large elderly population, and it is expected to increase along with the elderly population of the nation as a whole. Since the most important risk factor for Alzheimer’s disease is older age, it is not surprising that the prevalence of Alzheimer’s disease is projected to increase significantly over the next thirty-five years. This paper discusses the prevalence of Alzheimer’s disease in West Virginia, programs available to assist people and caregivers affected by the disease, and the associated economic burden of the disease.

Preventing And Treating Type 2 Diabetes Through A Physically Active Lifestyle, Raymond W. Leung, Jim Kamla, Man-Cheong Lee, Jennifer Y. Mak

Jennifer Y Mak

By the late 1960s, the increasing number of type 2 diabetic cases in children and adolescents rapidly presented a signifi cant public health issue recognized by the American Diabetes Association (2000). Since then, the prevalence of pediatric type 2 diabetes appears to be on the rise not only in the United States but all around the world (Gungor et al., 2005). In the United States, an increase from fewer than four percent to more than 50 percent of new cases of type 2 diabetes in the pediatric population was reported between the years of 1982 and 1998 (American Diabetes Association, …

Educating Nurses On The Use Of The Bedside Mobility Assessment Tool (Bmat) To Create A Culture Of Safety, Kaylin C. Laine

Master's Projects and Capstones

Healthcare workers are more at risk for injury than workers in any other industry, the injury rate in hospitals is almost double that of the entire private sector put together (OSHA, 2013). This high rate of injury has led hospital administrators and policymakers to take a closer look at the job duties and conditions of nurses and other healthcare workers. Almost half of all healthcare worker injuries are the result of overexertion or bodily reaction, injuries that occur as a result of performing patient handling tasks. Many US states have passed laws requiring hospitals to implement Safe Patient Handling and …

Fair Weight Loss After Gastric Rebanding For Slippage, Ahmed Dalmar, Maharaj Singh, Sara K. Roloff, Thomas Y. Chua

Maharaj Singh

Background: Laparoscopic adjustable gastric banding (LAGB) is one of the most common bariatric surgery procedures performed in the United States. LAGB results in safe and satisfactory weight loss, but it is often complicated with slippage, a complication requiring rebanding (reoperation). There is a paucity of studies and no uniform consensus regarding weight loss after rebanding.

Purpose: This study assessed the effect of rebanding for slippage after LAGB on weight loss up to five years.

Methods: This is a historical cohort study of 865 patients who underwent LAGB from 2001 to 2011. Rebanding was performed in 103 (11.9%) patients. Primary outcome …

The Effect Of Acute Aerobic Exercise On Hemostasis In Obstructive Sleep Apnea Patients, Ryan A. Martin

Masters Theses, 2010-2019

Purpose: To determine the hemostatic response after acute aerobic exercise in Obstructive Sleep Apnea (OSA). Methods: Eighteen males were recruited from the university and local community. Individuals who presented evidence of cardiovascular, pulmonary, or metabolic disease were excluded. Apnea-Hypopnea Index (AHI) > 5 was criteria for OSA. Subjects performed a treadmill exercise test at 35% and 70% predicted VO₂reserve during the morning hours. Pre exercise blood samples were obtained after 15 minutes supine rest and within two minutes following exercise. Repeated Measures ANOVA were performed for Factor VIII antigen, tPA antigen, tPA activity, and PAI-1 activity across two time …

Association Of Sleep Behavior To Physical Activity And Bmi In 9th And 10th Grade Students, Sonia Lina Davda

Senior Theses

Despite the topic’s popularity in research, the relationship between sleep duration and physical activity (PA) remains unclear. Measurement protocol differences, highly specific samples, and incomplete data contribute to varying results suggesting that additional research is needed. The purpose of the TRACK II study was to examine the relationship between PA, BMI, and self-reported sleep in adolescents. 369 9 th and 10 th grade students from 2 diverse school districts participated in the study. Participants completed a self-reported sleep questionnaire and had their height and weight measured. Demographic variables were also reported by participants. Actigraph accelerometers were used to objectively measure …

Policy Brief: Lifespan Respite Care Reauthorization Act, The 2015-2016 Cohort Of New Hampshire Leadership Education In Neurodevelopmental And Related Disabilities (Nh Lend) Program Trainees.

Policy Analysis

The Lifespan Respite Care Act (PL 109-442) provides critical support for families caring for loved ones at home. Family caregivers in the United States provide an estimated $470 billion worth of uncompensated care—a figure that exceeds the total Medicaid budget for 2013 (NAC Task Force, 2016). According to the National Respite Coalition, access to respite care helps protect caregiver health, strengthens families, keeps marriages intact, and prevents the need for expensive institutional long-term care. Reauthorization of the Lifespan Respite Care Act is essential to the well-being of individuals in need of long-term care and their families affected by long-term health …

Today - May 2016, Loma Linda University Health

TODAY

Inside this Issue:

-- More than 3,000 attend Loma Linda University Health Vision 2020 Groundbreaking Event
-- Sold-out LLUH Women's Conference inspires attendees to 'Be the Artist of Your Life'
-- Daniel Samano's two big home runs
-- Loma Linda University Health helps community discover 'Your Best Pathway to Health'
-- Annual Children's Day teaches kids about health care in a fun, safe environment
-- LLU alumna appointed as Florida surgeon general
-- ECMO open house displays new CARDIOHELP technology to help critically ill children survive
-- President Hart leads work bee to uncover original Loma Linda Sanitarium steps
-- …

The Impact Of Alzheimer’S Disease In An Aging Rural Population, Lynne J. Goebel, Vivian M. Minkemeyer, Courtney Wellman

Internal Medicine

West Virginia already has a large elderly population, and it is expected to increase along with the elderly population of the nation as a whole. Since the most important risk factor for Alzheimer’s disease is older age, it is not surprising that the prevalence of Alzheimer’s disease is projected to increase significantly over the next thirty-five years. This paper discusses the prevalence of Alzheimer’s disease in West Virginia, programs available to assist people and caregivers affected by the disease, and the associated economic burden of the disease.

Barriers And Facilitators Of Adolescent Health In Rural Kenya, Molly Secor-Turner, Brandy A. Randall, Courage Chikomborero Mudzongo

Faculty Publications - Doctor of Psychology (PsyD) Program

The purpose of this research was to identify perceived barriers and facilitators of health from the perspective of rural Kenyan adolescents and to characterize the cultural context that shapes these barriers and facilitators. Design: Following a semistructured interview guide, qualitative focus group interviews were conducted at day schools with 64 upper-primary and secondary students in rural central Kenya. Participants provided written parental consent and individual assent for study participation. Results: Findings were organized into seven categories (individual, family, peer, school, community, institutional, and cultural) according to a social–ecological framework to highlight the multiple social and environmental contexts that shape health …

Age-Associated B Cell And T Helper Cell Dysfunction In Rhesus Macaques, Evan Knox Stalvig

Theses and Dissertations

The immune system undergoes drastic changes as we age, known as immunosenescence. An example of this is the dysfunction and subpopulation distribution changes of immune cells. Due to immunosenescence, the elderly have a higher risk of complications and rapid progression of new challenges to the immune system, including human immunodeficiency virus (HIV). In an effort to determine the mechanism of dysfunction of humoral immunity due to age, I compared B cell and T cell responses to non-specific, mitogenic stimuli between aged and young adult rhesus macaque peripheral blood mononuclear cells (PBMCs). Analysis by flow cytometry revealed several differences in B …

The Influence Of Anti-Fatigue Matting On Gluteus Medius Muscle Activity During Functional Reaches, Marcus Payne

Health, Human Performance and Recreation Undergraduate Honors Theses

The purpose of this study was to look for changes in gluteus medius muscle activity during functional reaches and investigate whether or not anti-fatigue matting affects these changes. Fourteen participants (seven male & seven female) who did not meet any of the exclusion criteria completed forward and lateral reaches at hip and shoulder height on all four floor conditions for a total of sixteen reaches. Four floor types were tested: a control bare force platform, and a low, medium, and high stiffness anti-fatigue mat. Electromyography was applied bilaterally to the gluteus medius muscles, and maximum voluntary contractions were performed so …

Verification And Quantification Of Surface Electromyographic (Emg) Activity Of The Masseter Muscle, Kelsey Bowles

Honors Theses

Purpose: The goal of the present study is to develop and evaluate an automated technique for measuring biting and chewing related surface electromyographic (EMG) activity of the masseter muscle.

Methods: Data from 28 neurologically healthy participants between the ages of 18-40 were selected for this study. The procedure for collecting the bite/chew data consisted of the participant biting down and chewing three small breath mints while an EMG sensor recorded the masseter muscle activity. A five-step Matlab-based algorithm was created to accurately identify onsets and offsets of each bite and chew event.

Results: Compared to manual measurements using standard …