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Efficient In Vitro Development Of Photoreceptors From Human Pluripotent Stem Cells, Joseph C. Reynolds 2015 Dominican University of California

Efficient In Vitro Development Of Photoreceptors From Human Pluripotent Stem Cells, Joseph C. Reynolds

Master's Theses and Capstone Projects

Degeneration of the rod and cone photoreceptors in the human retina is among the most common causes of blindness. Replacing these damaged photoreceptors may help to restore vision. Repairing the damaged retina relies on the insertion of new, healthy cells. Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are two possible sources of photoreceptors to restore vision. Previous data shows that human ES cells and iPS cells can be differentiated into photoreceptors and transplanted into the eye to restore some vision. However, this process is inefficient, and costly. Here, we show a new method for inducing photoreceptor production ...


Ophthalmic Drugs 2015, Len V. Koh, Julie A. Helmus 2015 Pacific University

Ophthalmic Drugs 2015, Len V. Koh, Julie A. Helmus

Faculty Scholarship (COO)

A handy reference about ophthalmic drugs for students and clinicians in eye care profession.


Evidence Based Eye Care, Len V. Koh 2015 Pacific University

Evidence Based Eye Care, Len V. Koh

Faculty Scholarship (COO)

A summary of the results from numerous randomized clinical trials in eye care for students and clinicians.


A Guide To Scleral Lens Fitting (2 Ed.), Eef van der Worp 2015 College of Optometry, Pacific University

A Guide To Scleral Lens Fitting (2 Ed.), Eef Van Der Worp

Books and Monographs

A new, updated version of the Guide to Scleral Lens Fitting has been launched recently. As the editor of the guide, I had the pleasure of working with an international team of over twenty experts in the field – from all over the world.

Personally it feels like the guide only now is finalized, after so many years since its first edition. What started as a ‘simple’ revision of this first edition ended up as a complete makeover of the entire guide. Most probably – almost literally – not a single sentence came out untouched. Although some questions surely remain in the scleral ...


Impact Of Excess Light And Yellow Filters On Accumulation Of Lipofuscin, John R. Hayes, David K. Glabe 2014 Pacific University

Impact Of Excess Light And Yellow Filters On Accumulation Of Lipofuscin, John R. Hayes, David K. Glabe

Faculty Scholarship (COO)

Purpose. Previous reports suggest excess high energy, short wave light increase lipofuscin fluorophore accumulation in the retinal pigment epithelium layer. Oxidation of lipofuscin has been implicated in the genesis of macular degeneration. By taking advantage of the increased exposure to light by optometry students, we tested whether optometry students accumulate more lipofuscin fluorophores than similarly aged allied health students and whether yellow filters alter lipofuscin accumulation.

Method. The sample consisted of 54 non-optometry students (Mean age27, 4.1SD; 63% Female), 62 first-year optometry students (Mean age 27, 4.9SD; 55% female), and 39 second-year students (Mean age 26, 3.8SD ...


Knowledge, Attitudes And Practice Of Diabetes In Rural Bangladesh: The Bangladesh Population Based Diabetes And Eye Study, Fakir M. Amirul Islam, Rahul Chakrabarti, Mohamed Dirani, Mohamed T. Islam, Gail Ormsby, Mohamed Wahab, Christine Critchley, Robert P. Finger 2014 Swinburne University of Technology

Knowledge, Attitudes And Practice Of Diabetes In Rural Bangladesh: The Bangladesh Population Based Diabetes And Eye Study, Fakir M. Amirul Islam, Rahul Chakrabarti, Mohamed Dirani, Mohamed T. Islam, Gail Ormsby, Mohamed Wahab, Christine Critchley, Robert P. Finger

Education Papers and Journal Articles

Background: To assess the Knowledge, Attitudes and Practice (KAP) amongst the general community regarding type 2diabetes mellitus (DM) in rural Bangladesh.

Methods: Data was collected using cluster random sampling from 3104 adults residing in a rural district in Bangladesh.

Participants underwent a KAP questionnaire survey regarding assessing diabetes, socio-demographic and medical history.

Descriptive, Chi-square and regression analyses were performed.

Results: Participants were aged between 30 and 89 years (M = 51, SD = 11.8) and 65.5% were female. The prevalence of diabetes was found to be 8.3%. The majority (93%) reported to have heard of diabetes, yet only 4 ...


The Development Of A Public Optometry System In Mozambique: A Cost Benefit Analysis, James Loughman, Stephen Thompson, Geoff Harris, Luigi Bilotto, Jorge Ferrao, Kovin Naidoo 2014 Dublin Institute of Technology

The Development Of A Public Optometry System In Mozambique: A Cost Benefit Analysis, James Loughman, Stephen Thompson, Geoff Harris, Luigi Bilotto, Jorge Ferrao, Kovin Naidoo

Articles

Background: The economic burden of uncorrected refractive error (URE) is thought to be high in Mozambique, largely as a consequence of the lack of resources and systems to tackle this largely avoidable problem. The Mozambique Eyecare Project (MEP) has established the first optometry training and human resource deployment initiative to address the burden of URE in Lusophone Africa. The nature of the MEP programme provides the opportunity to determine, using Cost Benefit Analysis (CBA), whether investing in the establishment and delivery of a comprehensive system for optometry human resource development and public sector deployment is economically justifiable for Lusophone Africa ...


Congential Tritanopia: A Comparison Of Two Clinical Cases, James Kundart, Emma Lundien, Ron Mearsha, Janice Pierce, Oliver Kuhn-Wilken 2014 Pacific University

Congential Tritanopia: A Comparison Of Two Clinical Cases, James Kundart, Emma Lundien, Ron Mearsha, Janice Pierce, Oliver Kuhn-Wilken

Faculty Scholarship (COO)

This poster discusses two patient cases of presumed blue-yellow color deficiency in order to help optometrists care for this rare class of patients. Since this condition is extremely uncommon at birth, and is not possible to see by looking in the eye, practitioners may miss the symptoms of this condition. Optical treatment options are also discussed.


Diagnosis And Treatment Of Aniseikonia Associated With Pseudophakia And Penetrating Keratoplasty, James Kundart, Beth Kinoshita, Emily K. Bjore, Charlene M. Walton, Nicette Quintero 2014 Pacific University

Diagnosis And Treatment Of Aniseikonia Associated With Pseudophakia And Penetrating Keratoplasty, James Kundart, Beth Kinoshita, Emily K. Bjore, Charlene M. Walton, Nicette Quintero

Faculty Scholarship (COO)

Aniseikonia is defined as a perceived difference in image sizes between the two eyes. Post-surgical anisometropia continues to be the primary cause. Often contact lenses (CL) are used to treat the image size difference but sometimes the disparity is large enough to remain symptomatic even after CL correction. This case report details the diagnosis and treatment of a symptomatic patient with significant anisometropia, pseudophakia OS and post-penetrating keratoplasty OU secondary to keratoconus using size lenses and common clinical equipment.


Variables Affecting Dynamic Visual Acuity In Normal Adults, Ariene R. Clark 2013 Pacific University

Variables Affecting Dynamic Visual Acuity In Normal Adults, Ariene R. Clark

College of Optometry

ABSTRACT

Vision is one part of the balance system. The brain has to process, compile and make sense of self movement as well as movement in the environment using visual, vestibular and somatosensory information. Previous research has shown visual information reduction causes performance measures to decline in many physical tasks. Monocular blur is quite common, having several causes, some even voluntary. It is important to know if monocular blur causes any decreases in accurately interpreting the moving world, potentially impacting balance and safety. This research’s aim was to investigate whether a decrease in visual information with monocular blur is ...


A Comparative Cytotoxic Evaluation Of Acrylamide And Diacetone Acrylamide To Investigate Their Suitability For Holographic Photopolymer Formulations, Dervil Cody, Alan Casey, Izabela Naydenova, Emilia Mihaylova 2013 Dublin Institute of Technology

A Comparative Cytotoxic Evaluation Of Acrylamide And Diacetone Acrylamide To Investigate Their Suitability For Holographic Photopolymer Formulations, Dervil Cody, Alan Casey, Izabela Naydenova, Emilia Mihaylova

Articles

The comparative cytotoxic evaluation of two monomers Diacetone Acrylamide (DA) and Acrylamide (AA), used in holographic photopolymer formulations, is reported. Two normal cell lines were used: BEAS-2B and HaCaT. Cellular viability was assessed using the MTT assay for three different exposure times. A difference of two orders of magnitude is observed in the Lethal Dose (LD50) concentrations of the two monomers. Diacetone Acrylamide exhibits a significantly lower toxicity profile in comparison to Acrylamide at all exposure times. This result justifies the replacement of Acrylamide with Diacetone Acrylamide in the photopolymer formulation, with the view to reducing occupational hazard risks for ...


Blinded By The Light: Retinal Phototoxicity In The Context Of Safety Studies, Maria Cristina De Vera Mudry, Sven Kronenberg, Shun-ichiro Komatsu, Gustavo D. Aguirre 2013 University of Pennsylvania

Blinded By The Light: Retinal Phototoxicity In The Context Of Safety Studies, Maria Cristina De Vera Mudry, Sven Kronenberg, Shun-Ichiro Komatsu, Gustavo D. Aguirre

Departmental Papers (Vet)

No abstract provided.


Open Access Publishing: Opportunities And Challenges, James Kundart 2013 Pacific University

Open Access Publishing: Opportunities And Challenges, James Kundart

Faculty Scholarship (COO)

No abstract provided.


An Economic Analysis Of The Impact Of Refractive Error In Mozambique, Stephen J. Thompson 2013 Dublin Institute of Technology

An Economic Analysis Of The Impact Of Refractive Error In Mozambique, Stephen J. Thompson

Conference Papers

Mozambique eyecare project carried out in June 2013 to estimate the socio-economic benefit of an Optometry Programme by calculating the benefits of addressing refractive error in terms of productivity gained as a result of the intervention.


The Development Of A Public Optometry System In Mozambique: A Cost Benefit Analysis, Stephen J. Thompson, James Loughman 2013 Dublin Institute of Technology

The Development Of A Public Optometry System In Mozambique: A Cost Benefit Analysis, Stephen J. Thompson, James Loughman

Articles

The economic burden of uncorrected refractive error (URE) is thought to be high in Mozambique, largely as a consequence of the lack of resources and systems to tackle this largely avoidable problem. The Mozambique Eyecare Project (MEP) has established the first optometry training and human resource deployment initiative to address the burden of URE in Lusophone Africa. The nature of the MEP programme provides the opportunity to determine, using Cost Benefit Analysis (CBA), whether investing in the establishment and delivery of a comprehensive system for optometry human resource development and public sector deployment is economically justifiable for Lusophone Africa.


Considerations In The Design Of An Eye Health Programme For Nampula, Mozambique, Aoife Phelan, Lisa O'Donoghue, Kovin Naidoo, Kathryn Saunders, James Loughman 2013 Dublin Institute of Technology

Considerations In The Design Of An Eye Health Programme For Nampula, Mozambique, Aoife Phelan, Lisa O'Donoghue, Kovin Naidoo, Kathryn Saunders, James Loughman

Conference Papers

Introduction/Purpose:

There are almost twelve million children (<18 >years) in Mozambique with minimal access to eye care. [1] Annual screening of school children by teachers for uncorrected refractive error is one of the most cost effective health interventions in Sub Saharan Africa.[2] The International Agency for the Prevention of Blindness (IAPB) has recommended that child eye health interventions be incorporated into National School Health Initiatives.[3]

In view of the IAPB position this presentation sets out to identify and discuss the main considerations in the design of a child eye health strategy, for the province of Nampula, Mozambique, which ...


Considerations In The Design Of An Eye Health Programme For Nampula, Mozambique, Aoife Phelan, Lisa O'Donoghue, Kovin Naidoo, Kathryn Saunders, James Loughman 2013 Dublin Institute of Technology

Considerations In The Design Of An Eye Health Programme For Nampula, Mozambique, Aoife Phelan, Lisa O'Donoghue, Kovin Naidoo, Kathryn Saunders, James Loughman

Other

Introduction/Purpose:

There are almost twelve million children (<18 >years) in Mozambique with minimal access to eye care. [1] Annual screening of school children by teachers for uncorrected refractive error is one of the most cost effective health interventions in Sub Saharan Africa.[2] The International Agency for the Prevention of Blindness (IAPB) has recommended that child eye health interventions be incorporated into National School Health Initiatives.[3]

In view of the IAPB position this presentation sets out to identify and discuss the main considerations in the design of a child eye health strategy, for the province of Nampula, Mozambique, which ...


Evaluations Of Exit Competencies Of Optometrists In Mozambique, Kajal Shah, James Loughman 2013 Dublin Institute of Technology

Evaluations Of Exit Competencies Of Optometrists In Mozambique, Kajal Shah, James Loughman

Conference Papers

Introduction: The appropriate education for eye health workers is a key determinant of sustainable eye health care systems, and the solution to avoidable blindness and visual impairment. The Mozambique Eye care Project (MEP), is developing the country's first indigenously trained optometrists using a competency-based education curriculum.

Aims: The principal aim is to evaluate the exit clinical competencies of the first optometry graduates in Mozambique and to inform the evaluation of the competency curriculum.

Methods: Using UK based competencies as a benchmark; nine final year students were examined to assess competences in six core subjects.Further information about factors relating ...


Evaluations Of Exit Competencies Of Optometrists In Mozambique, Kajal Shah, James Loughman 2013 Dublin Institute of Technology

Evaluations Of Exit Competencies Of Optometrists In Mozambique, Kajal Shah, James Loughman

Other

Introduction: The appropriate education for eye health workers is a key determinant of sustainable eye health care systems, and the solution to avoidable blindness and visual impairment. The Mozambique Eye care Project (MEP), is developing the country's first indigenously trained optometrists using a competency-based education curriculum.

Aims: The principal aim is to evaluate the exit clinical competencies of the first optometry graduates in Mozambique and to inform the evaluation of the competency curriculum.

Methods: Using UK based competencies as a benchmark; nine final year students were examined to assess competences in six core subjects.Further information about factors relating ...


Addressing Disability In The Health System At Caritas Takeo Eye Hospital, Manfred Morchen, Gail Ormsby, Te Serey Bonn, David Lewis 2013 Takeo Eye Hospital

Addressing Disability In The Health System At Caritas Takeo Eye Hospital, Manfred Morchen, Gail Ormsby, Te Serey Bonn, David Lewis

Education Papers and Journal Articles

The article describes how the CARITAS Takeo Eye Hospital (CTEH) in Cambodia has worked hard to be more inclusive of people with disabilities. It mentions that the process to address the disability at the CTEH began in 2008 with the construction of new premises with universal design which reduced the physical barriers for everybody. The CTEH staff was trained on inclusion by CBM Australia and the Nossal Institute for Global Health; disability-inclusive practices reported a positive outcome.


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