In Vitro Growth Suppression Of Renal Carcinoma Cells By Curcumin, 2015 Aurora Research Institute, Aurora Health Care
In Vitro Growth Suppression Of Renal Carcinoma Cells By Curcumin, Santhi Konduri, Madhavi Latha Yadav Bangaru, Phu Thanh Do, Shenglin Chen, Jeffrey Woodliff, Sanjay Kansra
Journal of Patient-Centered Research and Reviews
Background: Malignant clear cell renal carcinoma (ccRCC) is an aggressive tumor that is highly resistant to chemotherapy and radiation. Current therapeutic approaches to management of ccRCC have not significantly improved patient survival, therefore novel therapies are needed. The von Hippel-Lindau tumor suppressor gene is frequently mutated in ccRCC resulting in unregulated transcriptional activity of hypoxia-inducible factors (HIF) 1α and 2α. HIF-mediated transcription leads to increased growth factor expression and growth factor receptor (GFR)-mediated signaling. NFκB and STAT3 are phosphorylated in response to GFR activation and modulate gene expression, which promotes cell growth and invasion. Activated NFκB and STAT3 expression ...
A Case Control Study Of Nutrient Intake Deficiencies In Patients Taking Warfarin, 2015 Marshall University Joan C Edwards School of Medicine
A Case Control Study Of Nutrient Intake Deficiencies In Patients Taking Warfarin, Philip Riley Iv, Kim Lucas Day, Md, George M. Yousef, Md, Sirisha Devabhaktuni, Md, Ashley N. Gaing, Lynne J. Goebel, Md
Marshall Journal of Medicine
We previously published the case of a woman taking warfarin who was found to have scurvy, a disease caused by a deficiency of vitamin C. This led us to hypothesize that patients taking warfarin who consume a diet limited in vitamin K rich foods may be at risk for other nutrient deficiencies. To test our hypothesis, we studied dietary nutrient intake in patients taking warfarin compared to patients with heart disease not taking warfarin.
The warfarin (n=59) and control groups (n=24) comprised convenience samples of patients with heart disease over age 60 years. Patients completed a ...
Use Of Animal Fat As A Symbol Of Health In Traditional Societies Suggests Humans May Be Well Adapted To Its Consumption, Miki Ben-Dor
Journal of Evolution and Health
Background and objectives: Recommendations to limit the dietary consumption of saturated fat have been adopted by public health organizations in most countries. However, recent scientific studies and reviews have questioned the alleged negative health claims regarding saturated fat.
This research aims to provide a historical, evolutionary point of view to the debate through a short review of evidence for animal fat consumption by Paleolithic and recent traditional societies, and the discernment of how recent traditional societies perceived animal fat in terms of health and other lifestyle aspects.
Methodology: Literature review of the importance of animal fat's dietary consumption in ...
The Dietary Habits And Nutrition Education Levels Of Parents Of Pre-School Children At A Community Head Start Program, Lisa Renee Keys
The health of America’s youth is jeopardized as obesity, often beginning in childhood, becomes a major epidemic. Parents have exceptional influence on their children, especially nutritionally, which impacts how their children grow and develop. Parents with minimal nutrition education and who do not practice healthy eating habits may unintentionally influence their children in practices that could lead to nutrition-related disease and/or obesity. This research evaluated the dietary habits and nutrition knowledge of parents of preschoolers at a community Head Start program in Lexington, KY, which served a high percentage of Hispanic children. The parents were given a survey ...
The Human And Environmental Health Impacts Of Food Quality Among Emergency Food Providers, 2015 University of San Francisco
The Human And Environmental Health Impacts Of Food Quality Among Emergency Food Providers, Alexina Cather
Human health and environmental health are inextricably entwined, and the ways in which we grow, process, package, transport, market, and consume food are critical factors for both human and environmental health. The current industrial food system in the United States has numerous adverse effects on environmental and human health, which significantly impact the millions of food insecure Americans who receive their nutritional needs from emergency food providers (American Public Health Association, 2007). The widespread food insecurity in the United States and the increasing prevalence of obesity among adults and children have drawn attention to the role that emergency food ...
The Evaluation Of Select Lifestyle Behavior Modification Following Participation In A Comprehensive Weight Management Clinic, 2015 Grand Valley State University
The Evaluation Of Select Lifestyle Behavior Modification Following Participation In A Comprehensive Weight Management Clinic, Jennifer L. Bowling
Over the last decades, obesity in the United States has reached epidemic proportion. Obesity rates have nearly doubled since 1960 when 43% of the United States population was overweight or obese and 1% was extremely obese. In 2012, approximately 69% of the US population was overweight or obese while 6.3% were extremely obese. Obesity rates are expected to progressively increase; therefore, interventions and guidelines are imperative in order to reduce the long term health risks of the Nation and to reduce overall health care costs (National Institute of Health [NIH], 2012).
Obesity increases morbidity resulting from associated hypertension, cardiovascular ...
Diet Self-Efficacy And Physical Self-Concept Of College Students At Risk For Eating Disorders, 2015 Department of Psychology, Florida International Univesity
Diet Self-Efficacy And Physical Self-Concept Of College Students At Risk For Eating Disorders, Leslie D. Frazier, Joan A. Vaccaro, Stephanie Garcia, Negar Fallahazad, Kapil Rathi, Alice Shrestha, Nancy Perez
Department of Dietetics and Nutrition
Background: Both eating disorders and body image dissatisfaction affect a high proportion of college students. Self-esteem and self-efficacy may be protective factors for eating disorders. The aim of this study was to evaluate diet self-efficacy, the confidence to maintain or lose weight, and its association with physical selfconcept using data from an online survey of health literacy, body image, and eating disorders.
Study Population and Methods: This cross-sectional study collected online survey data from college students within the United States. The inclusion criteria allowed for 1612 college students, ages 17-35 years (597 males, 1015 females) belonging to the following racial ...
Use Of Fortified Skimmed Breast Milk To Feed Infants With Postoperative Chylothorax, 2015 Oregon Health & Science University
Use Of Fortified Skimmed Breast Milk To Feed Infants With Postoperative Chylothorax, Guadaljupe Lopez
Background: Breast milk is the best source of nutrition for the infant but infants suffering from post-surgical chylothorax cannot consume breastmilk due to its high fat content. There is an interest among health care providers and mothers of infants with chylothorax to use skimmed, supplemented breast milk instead of specialized infant formulas.
Objective: The purpose of this study was to assess the nutritional intake, tolerance and growth of infants fed fortified skimmed breast milk compared to infants fed specialized infant formulas for the treatment of chylothorax following cardiothoracic surgery.
Study design: Expressed breast milk was skimmed by allowing it to ...
Vitamin D Supplementation Regimens For Hiv-Infected Patients : A Historical Chart Review, 2015 Oregon Health & Science University
Vitamin D Supplementation Regimens For Hiv-Infected Patients : A Historical Chart Review, Jeremy Dorance O'Neal
Vitamin D deficiency may be common among HIV infected individuals. Similar to individuals not affected by HIV, HIV-infected patients are affected by limited UV-B exposure and vitamin D deficient diet. However, HIV-infected patients may be at increased risk for insufficient vitamin D due to antiretroviral medication regimens that affect vitamin D metabolism and fat malabsorption due to HIV-related inflammation. In this historical chart review, we examined the prevalence of vitamin D insufficiency and assessed the comparative effectiveness of varying vitamin D repletion regimens in an HIV-infected cohort. The study population comprised patients from an outpatient HIV clinic who had vitamin ...
Nutrient Intake And Body Composition In Children With Phenylketonuria, 2015 Oregon Health & Science University
Nutrient Intake And Body Composition In Children With Phenylketonuria, Melissa M. Hammons
Background: A recent study showed significantly higher body fat percentage among subjects with phenylketonuria (PKU) compared to controls. Several studies have suggested a relationship between body composition and blood phenylalanine (phe) concentrations, but this has not been consistently reported in the literature. The body composition of patients with PKU followed at Doernbecher Children’s Hospital is unknown. Objective: We aimed to determine if there is a difference in body composition of patients with PKU and patients in the general pediatric population. Furthermore, within the population with PKU we aimed to determine if there is a relationship between body composition and ...
Improving Dental Care To The Elderly In A Nursing Home, 2015 University of San Francisco
Improving Dental Care To The Elderly In A Nursing Home, Cara M. Licavoli
The project is about the collaboration between Peninsula Health Care District (PHCD) and Apple Tree Dental (ATD) in a team approach to address the current issues of improving dental care of frail and elderly patients in nursing home facilities. The specific aim is to improve dental care of clients at the San Mateo County nursing home facility by 100% by May, 2015. The methods use in this project was the adaptation and implementation of existing dental/oral health assessment tools, that is nurse driven for patient assessment upon admission to the nursing facility. The process includes staff education regarding the ...
A Study Whether Humans Can Produce Free Fatty Acids For Tasting, 2015 Wofford College
A Study Whether Humans Can Produce Free Fatty Acids For Tasting, Emily Bacher
A growing concern throughout the world, especially the United States, is the health of our population. According to the National Health and Nutrition Examination Survey (NHANES) performed in 2009-2010, approximately 35% of both men and women in the United States are obese (Flegal, 2012). In 2005, more than 300,000 deaths in the United States were attributed to obesity. However, the World Health Organization listed obesity as one of ten most preventable health risks (Wilborn, 2005).
Why, then, do we as a society struggle so much with our weight? Some, such as Swinburn, believe this trend of obesity can be ...
Assessing The Nutrition Knowledge And Body Image Perceptions Of Minority Freshman At East Tennessee State University, 2015 East Tennessee State University
Assessing The Nutrition Knowledge And Body Image Perceptions Of Minority Freshman At East Tennessee State University, Michele L. Becerra
Undergraduate Honors Theses
The health status of African American and Hispanic communities is in need of intervention. These minority groups have a health disparity gap from other races. The incidences of hypertension, diabetes, and obesity are greater in the African American and Hispanic communities. There is a need to continue addressing the specific health issues, along with ideas of body perception, plaguing the African American and Hispanic populations in the United States. Such disparities typically include those who follow “western” diets, have a lack of exercise, are predisposed to chronic illness, as well as have a need for continuous education of the subject ...
The Missing Link: The Impact Of Nutrition Education And The School Lunch Program, 2015 The University of Southern Mississippi
The Missing Link: The Impact Of Nutrition Education And The School Lunch Program, Rachel E. Calhoun
In the U.S., the weight status of overweight and obesity in children is increasing from recent decades (Carrol & Ogden, 2010). Research shows that the prevalence of children developing chronic diseases is influenced by obesity and overweight statuses, shown by existing risk factors (Freedman, Dietz, Srinivasan, & Berenson, 1999). Recent legislation of the National School Lunch Program has aimed to improve the nutritional value of school lunches in elementary schools by requiring fruit and vegetable meal components be provided on each lunch tray (Nutrition Standards, 2012). This quasi experimental study aimed to increase fourth graders nutrition knowledge and fruit and vegetable ...
Transport Of Bovine Milk Exosomes By Human Colon Carcinoma Caco-2 Cells And Rat Small Intestinal Iec-6 Cells, 2015 University of Nebraska – Lincoln
Transport Of Bovine Milk Exosomes By Human Colon Carcinoma Caco-2 Cells And Rat Small Intestinal Iec-6 Cells, Tovah Wolf
Nutrition & Health Sciences Dissertations & Theses
We have reported that microRNAs (miRNAs, miRs) in bovine milk regulate human genes. In milk, many miRNAs are encapsulated in exosomes, thereby conferring protection against degradation and a pathway for intestinal transport of miRNAs. We hypothesized that the uptake of bovine exosomes in human intestinal colon carcinoma Caco-2 cells and rat primary small intestinal IEC-6 cells is mediated by endocytosis. Transport studies were carried out using fluorophore-labeled exosomes purified from bovine milk. The transport of bovine exosomes exhibited saturation kinetics at 37°C (Km= 55.5±48.6 µg/200 µL, Vmax= 0.083±0.057 ng exosomal ...
Oral Wellness: Using Occupational Therapy To Enhance Oral Hygiene Delivery In Long-Term Care, 2015 Dominican University of California
Oral Wellness: Using Occupational Therapy To Enhance Oral Hygiene Delivery In Long-Term Care, Lauryn J. Banovitz, Liberty Bellah, Rosemarie Lion
Master's Theses and Capstone Projects
Based on current literature, oral health in long-term care (LTC) facilities is frequently of low priority and does not follow evidence-based best practices. Poor oral health reduces the quality of life of older adult residents and patients and can lead to systemic diseases, such as cardiovascular disease, stroke, and pneumonia, the leading cause of death in LTC. Occupational therapists can play an instrumental role as oral care consultants, and educators, and can act as resource guides to raise the standards of oral care in LTC facilities.
This capstone project explored ways in which occupational therapy, a profession traditionally designated for ...
Language Proficiency, Citizenship, And Food Insecurity Among Predominantly Immigrant Caribbean Latinos In Massachusetts: A Masters Thesis, 2015 University of Massachusetts Medical School
Language Proficiency, Citizenship, And Food Insecurity Among Predominantly Immigrant Caribbean Latinos In Massachusetts: A Masters Thesis, Tariana V. Little
GSBS Dissertations and Theses
BACKGROUND: Latinos report higher food insecurity than the national average, and food insecurity has been associated with adverse health outcomes wherein Latinos experience disparities. This study quantified the independent effects of language-speaking proficiency and citizenship on increased food insecurity among a predominantly immigrant Caribbean Latino sample in Lawrence, Massachusetts.
METHODS: The analytic sample comprised 574 participants aged 21-83 who visited a community health center in 2011-2013. Food insecurity was assessed via the 6-item US Household Food Security Survey. Multivariable logistic modeling (adjusted for self-reported age group, gender, education, and marital status) examined the independent associations between language proficiency and citizenship ...
Anti-Inflammatory Diet For Inflammatory Bowel Disease (Ibd-Aid), 2015 University of Massachusetts Medical School
Anti-Inflammatory Diet For Inflammatory Bowel Disease (Ibd-Aid), Anne Barnard, Barbara C. Olendzki, Kathryn Post, Rachel Erdil, Gin-Fei Olendzki, Anne Foley, David R. Cave
Senior Scholars Program
Background: Inflammatory Bowel Disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic, immune-mediated inflammatory conditions of the gastrointestinal tract, which have increasingly been linked to dysbiosis, or an imbalance in the gut microbiome. Standard of care for IBD involves an often-evolving combination of anti-inflammatory, antibiotic, and immunomodulatory medications; however, the pharmacological approach is never curative, and medications routinely become ineffective for individual patients. Partially fueled by the increasing inadequacy of pharmacologic treatment regimens, there is emerging interest from patients regarding diet and its role in the pathogenesis and treatment of inflammatory diseases, demanding more in-depth and ...
Comparison Of Body Composition Assessment Techniques In Older Adult Females, 2015 Bowling Green State University
Comparison Of Body Composition Assessment Techniques In Older Adult Females, Lauren Yacapraro
Comparison of Body Composition Assessment Techniques in Older Adult Females
Introduction: As the aging population increases, the need for accurate assessment of chronic disease risk also increases. There is considerable debate over the best way to assess this risk. BMI is a weight-to-height ratio that is commonly used to assess adiposity and obesity related risk. However, it does not differentiate lean (i.e., muscle and bone) versus fat mass – the true predictors of obesity-related diseases (e.g., cardiovascular disease and diabetes). This is prevalent in post-menopausal women who often experience age-related gains in fat mass and losses in lean mass ...
Fueling Performance: Determining The Efficacy Of Low-Carbohydrate Diet Models For Athletic Populations, 2015 Western Michigan University
Fueling Performance: Determining The Efficacy Of Low-Carbohydrate Diet Models For Athletic Populations, Chelsea Jackle
Advocates of low-carbohydrate (LC) diets assert that these diets help lessen dependence on sugar while aiding in the metabolism of fat tissue. Additionally, it is believed that lipolysis helps dieters feel more energetic, lose weight, and improve physical performance. For these reasons, many athletes and active people are drawn to diets such as the Atkins Diet, the South Beach Diet, the Paleo Diet, and the Zone Diet. According to current evidence, excessive weight loss, ketosis, reduced glycogen availability, dehydration, and increased stress hormone levels make LC diets that severely limit carbohydrates disadvantageous for athletes. Although LC diets are widely followed ...