Using A Tailored Health Information Technology Driven Intervention To Improve Health Literacy And Medication Adherence (Talkingrx), Brenda Fay
Characterization Of Physicochemical And Thermal Properties Of Biofield Treated Ethyl Cellulose And Methyl Cellulose, Mahendra Trivedi
Mahendra Kumar Trivedi
Low Power Class B Power Amplifier For Healthcare Application, 2016 University of California, Irvine
Low Power Class B Power Amplifier For Healthcare Application, Wei Cai
Cedarville University School Of Pharmacy: Mission Is At The Core Of Who We Are, 2016 Cedarville University
Cedarville University School Of Pharmacy: Mission Is At The Core Of Who We Are, Thaddeus T. Franz, Phillip L. Thornton, Jeffrey L. Huston, Melody L. Hartzler, Emily M. Laswell, Kasandra Chambers
Thaddeus T. Franz, R.Ph., Pharm.D.
No abstract provided.
Glp-1 Agonists In Type 1 Diabetes Mellitus: A Review Of The Literature, 2016 Butler University
Glp-1 Agonists In Type 1 Diabetes Mellitus: A Review Of The Literature, Kristin M. Janzen, Taylor D. Steuber, Sarah A. Nisly
Sarah A. Nisly
Objective: To review the use of GLP-1 agonists in patients with type 1 diabetes mellitus (T1DM). Data Sources: A search using the MEDLINE database, EMBASE, and Cochrane Database was performed through March 2016 using the search terms glucagon-like peptide 1 (GLP-1) agonists, incretin, liraglutide, exenatide, albiglutide, dulaglutide, type 1 diabetes mellitus. Study Selection and Data Extraction: All English-language trials that examined glycemic end points using GLP- 1 agonists in humans with T1DM were included. Data Synthesis: A total of 9 clinical trials examining the use of GLP-1 agonists in T1DM were identified. On average, hemoglobin A1C (A1C) was lower than ...
The Impact Of Incorporating Of Pharmacogenomics Into The Pharmacy Curriculum On Student Interest, 2016 Touro University of California
The Impact Of Incorporating Of Pharmacogenomics Into The Pharmacy Curriculum On Student Interest, Natalya Vaksman, Mitchell Barnett, Leann Hakobyan, Ilya Kutcher, Maggie Louie
Background: Pharmacogenomics content in the pharmacy curriculum has increased since AACP adopted NCHPEG guidelines in 2001. Aims: To evaluate how program level curricular changes impact pharmacy student opinions regarding pharmacogenomics, and gauge student interest in pursuing a career in pharmacogenomics. Methods: First and third year students from eight pharmacy schools in California completed a survey indicating their attitudes towards pharmacogenomics. Results: The survey concluded that the presence of a stand-alone pharmacogenomics course did not impact student perceived preparedness for a career in pharmacogenomics. Furthermore, the presence of a course did not influence student interest in pursuing a residency, fellowship, or ...
Calcium Phosphate As A Key Material For Socially Responsible Tissue Engineering, 2016 Chapman University
Calcium Phosphate As A Key Material For Socially Responsible Tissue Engineering, Vuk Uskoković, Victoria M. Wu
Pharmacy Faculty Articles and Research
Socially responsible technologies are designed while taking into consideration the socioeconomic, geopolitical and environmental limitations of regions in which they will be implemented. In the medical context, this involves making therapeutic platforms more accessible and affordable to patients in poor regions of the world wherein a given disease is endemic. This often necessitates going against the reigning trend of making therapeutic nanoparticles ever more structurally complex and expensive. However, studies aimed at simplifying materials and formulations while maintaining the functionality and therapeutic response of their more complex counterparts seldom provoke a significant interest in the scientific community. In this review ...
Did A Physician-Targeted Intervention That Reduced Potentially Inappropriate Prescribing To Elderly Patients Also Reduce Related Hospitalizations?, 2016 Jefferson College of Population Health, Thomas Jefferson University
Did A Physician-Targeted Intervention That Reduced Potentially Inappropriate Prescribing To Elderly Patients Also Reduce Related Hospitalizations?, Jacquelyn Mcrae, Pharmd, Sarah E. Hegarty, Pharmd, M. Alcusky, A. Vegesna, S. Varga, S. W. Keith, S. Del Canale, M. Lombardi, Vittorio Maio, Pharmd, Msph
Jefferson College of Population Health Posters
To determine whether a general practitioner focused intervention aimed at decreasing PIM prescribing in the elderly can decrease the risk of PIM-related hospitalizations.
Poster presented at 2016 ISPOR conference in Washington DC.
Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, 2016 Augustana College, Rock Island Illinois
Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez
Biology: Student Scholarship & Creative Works
ABSTRACT: The HIV-1 pandemic continues to thrive due to ineffective HIV-1 vaccines. Historically, the world’s most infectious diseases, such as polio and smallpox, have been eradicated or have come close to eradication due to the advent of effective vaccines. Highly active antiretroviral therapy is able to delay the onset of AIDS but can neither rid the body of HIV-1 proviral DNA nor prevent further transmission. A prophylactic vaccine that prevents the various mechanisms HIV-1 has to evade and attack our immune system is needed to end the HIV-1 pandemic. Recent advances in engineered nuclease systems, like the CRISPR/Cas9 ...
Biosimilars In Rheumatology: What The Clinician Should Know, 2016 National Polytechnic Institute
Biosimilars In Rheumatology: What The Clinician Should Know, Gilberto Castaneda-Hernandez, Rodrigo Gonzalez-Ramirez, Jonathan Kay, Morton A. Scheinberg
Biosimilars are now a reality in rheumatology. Although analytical and non-clinical procedures to establish similarity have evolved significantly, clinical trials demonstrating equivalent efficacy and safety are absolutely required for all biosimilars. The design of such trials, including equivalence and non-inferiority statistical approaches, are discussed. Clinical evidence on biosimilars that have been approved recently or are presently being developed for use in rheumatology is also reviewed and contrasted with that available for biomimics (or intended copies), which are non-innovator biologics that are marketed in several countries but have not undergone review according to a regulatory pathway for biosimilars.
Improving Collaboration Between Pharmacists And Physicians, 2016 Butler University
Improving Collaboration Between Pharmacists And Physicians, Paras Patel
Physicians and pharmacists have differing but complementary roles that can optimize patient care when structured effectively. Unfortunately, these two professionals are not collaborating well enough, as patient outcomes, especially in relation to medication adherence, continue to decline. Coordinated care of patients can improve by expanding bidirectional communication and sharing additional patient information with each other. It will be necessary to continue to promote collaborative care in the educational and training stages of these professionals’ careers to build trust and understanding of professional scope. Ultimately, the healthcare infrastructure will have to continue to progress to make collaboration more available and valuable ...
An N Of One: My Review Of Management Of Type 1 Diabetes, Myself As Patient, 2016 Butler University
An N Of One: My Review Of Management Of Type 1 Diabetes, Myself As Patient, Jarred Daugherty
As technology has advanced, so has the management of diabetes. Insulin, the essential medication for type 1 diabetes, is marketed in an array of formulations and devices. Continuous glucose monitors (CGM) can be inserted to measure blood glucose every 5 minutes. The rise of social media has given diabetics online support groups, where they can share their story and learn from others overcoming similar challenges. So, how well do the current diabetes management strategies work? My name Is Jarred and I’m a type 1 diabetic. I have tried many of these products and this article is a review of ...
School Of Pharmacy Inaugural Hooding Ceremony, 2016 Cedarville University
School Of Pharmacy Inaugural Hooding Ceremony, Cedarville University
Doctor of Pharmacy Hooding Ceremony
May 6, 2016
Engineering A Mutation In The Heparin Binding Pocket Of The Human Fibroblast Growth Factor, 2016 University of Arkansas, Fayetteville
Engineering A Mutation In The Heparin Binding Pocket Of The Human Fibroblast Growth Factor, Roshni Patel
Chemistry & Biochemistry Undergraduate Honors Theses
Fibroblast growth factors (FGFs) are family of proteins that belong to a group of growth factors that are found in mammals and play an important role in angiogenesis, differentiation, organogenesis, and tissue repair. In summary, their main functionality is involved in cell division and proliferation. Because FGFs plays such a vital role in cell proliferation, they are mainly involved in the process of wound healing and injuries. FGF binds to its ligand, heparin—a heavily sulfated glycosaminoglycan. The binding of heparin to FGF occurs through electrostatic interactions, specifically between the negatively charged sulfate groups on heparin and positively charged residues ...
An Investigation Into Formulation And Therapeutic Effectiveness Of Nanoparticle Drug Delivery For Select Pharmaceutical Agents, 2016 East Tennessee State Universtiy
An Investigation Into Formulation And Therapeutic Effectiveness Of Nanoparticle Drug Delivery For Select Pharmaceutical Agents, Dustin Cooper
Electronic Theses and Dissertations
Drug based nanoparticle (NP) formulations have gained considerable attention over the past decade for their use in various drug delivery systems. NPs have been shown to increase bioavailability, decrease side effects of highly toxic drugs, and prolong drug release. Furthermore, polymer based, biodegradable nanodelivery has become increasing popular in the field of NP formulation because of their high degree of compatibility and low rate of toxicity. Due to their popularity, commercially available polymers such as poly lactic acid (PLA), poly glycolic acid (PGA) and polylactic-co-glycolic acid (PLGA) are commonly used in the development and design of new nano based delivery ...
A Model For The Voltammetric Behaviour Of Tio2 Memristors, 2016 Dublin Institute of Technology
A Model For The Voltammetric Behaviour Of Tio2 Memristors, John Cassidy, Daryl Fox, Tony Betts
Abstract A model is solved based on the Nernst Planck equation to calculate the diffusion and migration currents for a species in a thin layer (about 200 nm) confined between two electrodes. This is proposed to account for the current voltage behaviour of a memristor constructed in a similar fashion. At the working electrode, an electroactive species is oxidised and at the counter electrode, the same species is reduced. Upon application of a simple voltammetric waveform, the migration current exhibits a resistance profile at slow scan rates and hysteresis at faster scan rates, indicative of memristor behavior.
Pharmacologic And Clinical Evaluation Of Posaconazole., 2016 Thomas Jefferson University
Pharmacologic And Clinical Evaluation Of Posaconazole., Jason N. Moore, Jason R. Healy, Walter K. Kraft
Department of Pharmacology and Experimental Therapeutics Faculty Papers
Posaconazole, a broad-spectrum triazole antifungal agent, is approved for the prevention of invasive aspergillosis and candidiasis in addition to the treatment of oropharyngeal candidiasis. There is evidence of efficacy in the treatment and prevention of rarer, more difficult-to-treat fungal infections. Posaconazole oral suspension solution has shown limitations with respect to fasting state absorption, elevated gastrointestinal pH and increased motility. The newly approved delayed-release oral tablet and intravenous solution formulations provide an attractive treatment option by reducing interpatient variability and providing flexibility in critically ill patients. On the basis of clinical experience and further clinical studies, posaconazole was found to be ...
Ssri Use In Pregnancy And Congenital Heart Defects: A Meta-Analysis Of Population Based Cohort Studies, 2016 University of Rhode Island
Ssri Use In Pregnancy And Congenital Heart Defects: A Meta-Analysis Of Population Based Cohort Studies, Elizabeth A. Kowalik
Senior Honors Projects
The American College of Obstetricians and Gynecologists estimate that 10-23% of pregnant women in the US face depression at some point during their pregnancy. However, no clear recommendations regarding the treatment of depression in pregnancy are available. Antidepressants are commonly used during pregnancy without clear evidence of their safety. A study of 1,106,757 women in 47 states found that 89,980 (8.1%) had taken an antidepressant at some point during their pregnancy. The Centers for Disease Control and Prevention (CDC) found that 298 (4.5%) of 6582 women in 10 states between the years of 1998 and ...
Upregulation Of Antibiotic Activity Of A Streptomyces Sp. Via Co-Cultures With Challenge Pathogens, 2016 University of Connecticut - Storrs
Upregulation Of Antibiotic Activity Of A Streptomyces Sp. Via Co-Cultures With Challenge Pathogens, Anne A. Sung
Honors Scholar Theses
Marine natural product drug discovery has begun to play an important role in the treatment of diseases. Early drug discovery from natural products came primarily from plants, but after the discovery and development of penicillin, scientists started looking at natural products from microorganisms. Numerous natural products have been discovered from members of the order Actinomycetales, particularly in the genus Streptomyces, due to their metabolic diversity in the production of biologically active secondary metabolites. Ascidians, also known as tunicates, are marine invertebrates that contain many host-associated microbes. Adult tunicates are sessile, which makes them vulnerable to predators, and thus, they are ...
The Potentiating Effects Of Acetaminophen On Oxidant Air Pollutant Sensory Irritation And The Onset Of Asthma, 2016 University of Connecticut
The Potentiating Effects Of Acetaminophen On Oxidant Air Pollutant Sensory Irritation And The Onset Of Asthma, Bennett J. Doughty
Honors Scholar Theses
Through its toxic metabolites, acetaminophen can cause oxidative injury in the liver. This damage has not yet been investigated in the respiratory tract. If acetaminophen also causes oxidative stress and injury here, this widely used antipyretic could potentiate the adverse effects of oxidant air pollutants. Thus, the primary goal of this project is to determine if low non-hepatotoxic doses of APAP is correlated with an increase of oxidative stress in the airways, possibly linking APAP to the onset of asthma. Using data that reflected murine breathing patterns, the addition of acetaminophen greatly increased the reflex irritant response to ETS through ...