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Improving Healthcare Outcomes Through An Interdisciplinary Effort Of Social Work And Pharmacy In A “Village” Model Setting, Elizabeth Hipp, Lauren Post 2015 Ohio State University - Main Campus

Improving Healthcare Outcomes Through An Interdisciplinary Effort Of Social Work And Pharmacy In A “Village” Model Setting, Elizabeth Hipp, Lauren Post

Ohio Association of Gerontology and Education Conference

OAGE is an association of educators, researchers, professionals, and students in Ohio dedicated to gerontological education, research and practice. The organization promotes gerontological education, supports Ohio's aging network as a resource for research and practice, and provides professional development for students, faculty and professionals.

OAGE is committed to maintaining close working relationships with the Ohio Department of Aging, the Ohio Area Agencies on Aging, Ohio's post secondary institutions, and all professional organizations and individuals in the aging network.


Obafluorin: A Potential Inhibitor Of Serine Hydroxymethyl Trasferase, Neha Prasad 2015 Washington University in St Louis

Obafluorin: A Potential Inhibitor Of Serine Hydroxymethyl Trasferase, Neha Prasad

Undergraduate Research Symposium Posters & Abstracts

In the golden age of drug discovery, scientists turned to nature to find and emulate molecules with pharmacological activity. The beta-lactam ring in penicillin has proven to be one of the most important classes of antibiotics of the last century. The molecule I am studying, obafluorine, was isolated from Pseudomonas fluorescens and has a beta-lactone ring in its structure—a close relative of the beta-lactam ring in Penicillin. Obafluorin was isolated as a broad-spectrum antibacterial and antifungal agent that could have therapeutic properties, but its cellular target is still unknown. The Wencewicz Lab in the WUSTL Department of Chemistry is ...


Exploration Of Putative Mitochondrial Gene Expression In Crithidia Fasciculata As A Model For Pathogenic Trypanosomes Causing Human Disease, Baylye Boxall, Nadjean Sagesse 2015 Georgia State University

Exploration Of Putative Mitochondrial Gene Expression In Crithidia Fasciculata As A Model For Pathogenic Trypanosomes Causing Human Disease, Baylye Boxall, Nadjean Sagesse

Georgia State Undergraduate Research Conference

No abstract provided.


Community Education On Mtm Services, Samantha A. Smolinski, Kristin Lessig, Lindsay M. Mailloux, Jacob M. Davis, Stephen K. Yeboah 2015 Cedarville University

Community Education On Mtm Services, Samantha A. Smolinski, Kristin Lessig, Lindsay M. Mailloux, Jacob M. Davis, Stephen K. Yeboah

The Research and Scholarship Symposium

Background: Medication nonadherence, defined as “the number of doses not taken or taken incorrectly that jeopardizes the patient’s therapeutic outcome,” is a major health problem with about 43% of the general population nonadherent to their medications. Medication nonadherence accounts for an estimated 125,000 deaths per year in the US, 33-69% of medication-related hospital readmissions, and an estimated $100 to $300 billion in direct and indirect medical costs. Medication therapy management (MTM), defined as “a distinct service or group of services that optimize therapeutic outcomes for individual patients,” has been found to reduce medication nonadherence. However, many individuals eligible ...


Pharmaceutical Stability Of Promethazine In Iv Infusion Fluids, Michael E. Kapraly, Denise S. Simpson, Joshua Knoebel, Ruth Choi, Brandon Kime, Samson Amos, Rebecca J. Gryka, Kaysie J. Brittenham 2015 Cedarville University

Pharmaceutical Stability Of Promethazine In Iv Infusion Fluids, Michael E. Kapraly, Denise S. Simpson, Joshua Knoebel, Ruth Choi, Brandon Kime, Samson Amos, Rebecca J. Gryka, Kaysie J. Brittenham

The Research and Scholarship Symposium

BACKGROUND: Promethazine is an antiemetic often administered intravenously in healthcare facilities for postoperative nausea and vomiting. Due to potential adverse events that may result with intravenous push administration, some safety-minded healthcare facilities have elected to use alternative methods of administration. One such method is the intravenous piggyback (IVPB). However, limited stability data exist for promethazine in intravenous solutions.

OBJECTIVE: To analyze the stability over time of promethazine dissolved in commonly used intravenous infusion fluids when exposed to various light and temperature conditions.

PROPOSED METHODS: Promethazine will be formulated into IVPB bags of normal saline, dextrose 5% in water and Lactated ...


Gmo Vs. Non-Gmo: Comparing The Addictiveness Of Corn In Rats, Sara L. Hill, Courtney Noll, Tyler Michael, Kelly A. Huston, Christian A. Carroll 2015 Cedarville University

Gmo Vs. Non-Gmo: Comparing The Addictiveness Of Corn In Rats, Sara L. Hill, Courtney Noll, Tyler Michael, Kelly A. Huston, Christian A. Carroll

The Research and Scholarship Symposium

Genetically modified organisms (GMOs) refer to organisms whose DNA has been altered to produce a certain characteristic. GMOs account for a significant proportion of the crops produced in the United States. Specifically, GMO corn accounted for approximately 88% of all corn grown for human and animal consumption in the year 2012. Previously conducted studies have not uniformly demonstrated the safe use of GMO corn, and no studies have been conducted to analyze the addictiveness of GMO corn.

The idea of addiction refers to more than just a physical dependence, but to a psychological dependence on something as well. Addiction is ...


Asthma Knowledge, Control, And Administration Techniques In Hispanic Caregivers Of Pediatrics, Rachel Culp, Amy Wuobio, Jon Wilkie, Benjamin Robertson, Joshua Arnold, Kyle Hultz 2015 Cedarville University

Asthma Knowledge, Control, And Administration Techniques In Hispanic Caregivers Of Pediatrics, Rachel Culp, Amy Wuobio, Jon Wilkie, Benjamin Robertson, Joshua Arnold, Kyle Hultz

The Research and Scholarship Symposium

Objectives: The objectives of this study were to (1) describe asthma knowledge, control, and administration techniques in Hispanic caregivers of pediatric asthma patients in primary care clinics and (2) determine the association between asthma knowledge and control.

Methods: A pilot, cross-sectional study was conducted by administering a survey to Spanish-speaking primary caregivers of children under 12 years old with a current diagnosis of asthma. The survey contained: demographic questions (8 items), a modified version of the Asthma Control Test (ACT, 5 self-assessment items, 5-point, Likert-type scale), knowledge (21 items, correct/incorrect response), and inhaler use (1 item, rank ordering steps ...


Simulation-Based Interdisciplinary Team Learning—Pilot Study, Bethany Sibbitt, Brian C. Patterson, Adam H. Altman, Brittani H. Purkeypile, Zachary IlGiovine, Nicholaus Christian, Phillip J. Wenzell, Natasha Mehta, Raymond Ten Eyck 2015 Cedarville University

Simulation-Based Interdisciplinary Team Learning—Pilot Study, Bethany Sibbitt, Brian C. Patterson, Adam H. Altman, Brittani H. Purkeypile, Zachary Ilgiovine, Nicholaus Christian, Phillip J. Wenzell, Natasha Mehta, Raymond Ten Eyck

The Research and Scholarship Symposium

Background: Currently, interprofessional education (IPE) is becoming widely integrated into healthcare professional education with regulating bodies including IPE as a curricular requirement. Although recent studies have concluded that students value IPE, there are a number of challenges associated with initial engagement. Many schools are unsure how to approach this interdisciplinary integration. In addition to IPE, simulation has become an important tool in the education of health professionals. As the first exercise at Wright State University involving interprofessional groups composed completely of undergraduates, interested students from the Boonshoft School of Medicine, the WSU College of Nursing and Health, and the Cedarville ...


Cilia Have A Significant Role In Regulating Cell Size In Response To Fluid Flow Induced Shear Stress In A Flow Chamber, Schuyler E. Price, Ryan M. Hecklinger, Matthew B. Welkie Jr., Timothy L. Norman, Elisha R. Injeti 2015 Cedarville University

Cilia Have A Significant Role In Regulating Cell Size In Response To Fluid Flow Induced Shear Stress In A Flow Chamber, Schuyler E. Price, Ryan M. Hecklinger, Matthew B. Welkie Jr., Timothy L. Norman, Elisha R. Injeti

The Research and Scholarship Symposium

Cilia are hair-like protrusions on the apical surface of cells. Their function is to relay mechanical signals like shear stress from extracellular into intracellular environment and thereby maintain cellular homeostasis. Ciliary dysfunctions include polycystic kidney disease and new therapeutic interventions based on ciliary function are under investigation. The current study evaluates the use of a custom designed fluid flow chamber’s ability to study the role of cilia in regulating cell size in response to shear stress.

A fluid flow chamber that continually maintains laminar flow at different flow rates and temperature was designed. Endothelial wild type cells (ETWT) that ...


Medication Reconciliation Of Medically-Complex Emergency Department Patients By Second-Year Professional Pharmacy Students, Neal S. Fox, Lauren Haines 2015 Cedarville University

Medication Reconciliation Of Medically-Complex Emergency Department Patients By Second-Year Professional Pharmacy Students, Neal S. Fox, Lauren Haines

The Research and Scholarship Symposium

Background: There is a high potential for medication discrepancies to occur during patient care transitions. However, health professionals must find ways to reduce these and improve patient care, such as with medication reconciliation. This intervention is used to identify a patient’s most accurate medication list by comparing the medical record to another list obtained from the patient, hospital, or other provider. Pharmacists have a major role in this process because of their medicinal expertise, but paying them is expensive, so using students may be more cost-effective. Research has examined fourth-year professional pharmacy students (P4s) performing medication reconciliation during their ...


2015 Symposium Overview, Cedarville University 2015 Cedarville University

2015 Symposium Overview, Cedarville University

The Research and Scholarship Symposium

Click the "Download" button in the top right corner to view the abstract booklet.


Evaluating Antioxidant Activity Of Selected Plant Species Grown In Cedarville, Ohio, Daniel A. Benson, Joshua A. Sitler, Alexander P. Treide, David Woodfield, Denise S. Simpson, Robert L. Paris 2015 Cedarville University

Evaluating Antioxidant Activity Of Selected Plant Species Grown In Cedarville, Ohio, Daniel A. Benson, Joshua A. Sitler, Alexander P. Treide, David Woodfield, Denise S. Simpson, Robert L. Paris

The Research and Scholarship Symposium

Over the past several decades, there has been an increase in the number of synthetic drug molecules developed and utilized to treat various conditions. Although these synthetic drugs have proven useful, there has been growing public concern regarding the potentially negative long-term effects of synthetic agents on the body. As a result, there has been an increased interest in identifying and utilizing plant extracts and purified compounds since they are perceived to be a more natural alternative to synthetic drugs. The goal of this study was to evaluate the specific antioxidant properties of alsike clover Trifolum hybridum when produced under ...


Facilitating Facilitators: Enhancing Pbl Through A Structured Facilitator Development Program, Francine D. Salinitri, Sheila M. Wilhelm, Brian L. Crabtree 2015 Wayne State University

Facilitating Facilitators: Enhancing Pbl Through A Structured Facilitator Development Program, Francine D. Salinitri, Sheila M. Wilhelm, Brian L. Crabtree

Interdisciplinary Journal of Problem-Based Learning

With increasing adoption of the problem-based learning (PBL) model, creative approaches to enhancing facilitator training and optimizing resources to maintain effective learning in small groups is essential. We describe a theoretical framework for the development of a PBL facilitator training program that uses the constructivist approach as the program’s guiding philosophy. The structured, pedagogically sound program was designed for a multidisciplinary pool of basic and social/administrative scientists, clinical faculty, practicing pharmacists, and post-graduate residents enrolled in a teaching certificate program. The training program employs the PBL experience, along with interactive technology, case-based and debriefing sessions with small groups ...


Maternal Nicotine Exposure Leads To Impaired Disulfide Bond Formation And Augmented Endoplasmic Reticulum Stress In The Rat Placenta, Michael Wong, Catherine J. Nicholson, Alison C. Holloway, Daniwl Hardy 2015 Western University

Maternal Nicotine Exposure Leads To Impaired Disulfide Bond Formation And Augmented Endoplasmic Reticulum Stress In The Rat Placenta, Michael Wong, Catherine J. Nicholson, Alison C. Holloway, Daniwl Hardy

Physiology and Pharmacology Publications

Maternal nicotine exposure has been associated with many adverse fetal and placental outcomes. Although underlying mechanisms remain elusive, recent studies have identified that augmented endoplasmic reticulum (ER) stress is linked to placental insufficiency. Moreover, ER function depends on proper disulfide bond formation-a partially oxygen-dependent process mediated by protein disulfide isomerase (PDI) and ER oxidoreductases. Given that nicotine compromised placental development in the rat, and placental insufficiency has been associated with poor disulfide bond formation and ER stress, we hypothesized that maternal nicotine exposure leads to both placental ER stress and impaired disulfide bond formation. To test this hypothesis, female Wistar ...


The Use Of Pbl In An Interprofessional Education Course For Health Care Professional Students, Kristine M. L'Ecuyer, David Pole, Sheila A. Leander 2015 Saint Louis University

The Use Of Pbl In An Interprofessional Education Course For Health Care Professional Students, Kristine M. L'Ecuyer, David Pole, Sheila A. Leander

Interdisciplinary Journal of Problem-Based Learning

A problem-based learning (PBL) framework was utilized in a series of six interprofessional team seminars (IPTS) for postbaccalaureate students from seven health professions. The goal of IPTS was to develop a collaborative practice-ready workforce prepared to respond to patient care needs through use of concrete examples, skills development, critical thinking, and problem solving in safe, faculty-facilitated small groups. The collaborative nature of PBL closely correlates with teaching methodologies of the IPTS series. This study analyzed critical reflection assignments of nursing students in accelerated programs to determine the effectiveness of IPTS at preparing students for interprofessional collaborative practice. Findings indicated that ...


Proteomic Signature Of The Murine Intervertebral Disc, Matthew R. McCann 2015 Western University

Proteomic Signature Of The Murine Intervertebral Disc, Matthew R. Mccann

Physiology and Pharmacology Publications

Low back pain is the most common musculoskeletal problem and the single most common cause of disability, often attributed to degeneration of the intervertebral disc. Lack of effective treatment is directly related to our limited understanding of the pathways responsible for maintaining disc health. While transcriptional analysis has permitted initial insights into the biology of the intervertebral disc, complete proteomic characterization is required. We therefore employed liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) protein/peptide separation and mass spectrometric analyses to characterize the protein content of intervertebral discs from skeletally mature wild-type mice. A total of 1360 proteins ...


Representatives Perales, Hackett Participate In Healthcare Forum, Mark D. Weinstein 2015 Cedarville University

Representatives Perales, Hackett Participate In Healthcare Forum, Mark D. Weinstein

News Releases

Cedarville University School of Pharmacy will host a policy forum on healthcare legislation with State Representatives Rick Perales and Bob Hackett along with Antonio Ciaccia, director of government and public affairs from the Ohio Pharmacist Association. The event, open to the public, will be held on Thursday, Feb. 5, in the Health Sciences Center in Room 107 beginning at 5:30 p.m.

This event will allow students to interact with representatives on legislative issues related to pharmacy. Currently the topics set in place for the forum are: student involvement, advocacy and communication with legislators, health care reform, Provider Status ...


Acid-Suppressing Agents And Risk For Clostridium Difficile Infection In Pediatric Patients, Katelyn E. Brown, Chad A. Knoderer, Kristen R. Nichols, Ashley S. Crumby 2015 Butler University

Acid-Suppressing Agents And Risk For Clostridium Difficile Infection In Pediatric Patients, Katelyn E. Brown, Chad A. Knoderer, Kristen R. Nichols, Ashley S. Crumby

Scholarship and Professional Work – COPHS

Background. Acid-suppressing agents have been associated with increased Clostridium difficile infection (CDI) in adults. The objective of this study was to evaluate the association of acid-suppressing therapy with the development of CDI in the pediatric population.

Methods. This was a retrospective case-control study. Children aged 1 through 17 years with a positive C difficile polymerase chain reaction (PCR) result obtained between June 1, 2008, and June 1, 2012, were randomly matched to a control population selected from patients with negative PCR.

Results. A total of 458 children were included. No difference was observed in acid-suppressive therapy prior to PCR in ...


Implementing Extended-Infusion Cefepime As Standard Of Care In A Children’S Hospital: A Prospective Descriptive Study, Kristen R. Nichols, Lauren C. Karmire, Elaine G. Cox, Michael B. Kays, Chad A. Knoderer 2015 Butler University

Implementing Extended-Infusion Cefepime As Standard Of Care In A Children’S Hospital: A Prospective Descriptive Study, Kristen R. Nichols, Lauren C. Karmire, Elaine G. Cox, Michael B. Kays, Chad A. Knoderer

Scholarship and Professional Work – COPHS

Background: Extended-infusion cefepime (EIC) has been associated with decreased mortality in adults, but to our knowledge, there are no studies in children.

Objective: The objective of this study was to determine the feasibility of implementing EIC as the standard dosing strategy in a pediatric population.

Methods: This was a descriptive study of children aged 1 month to 17 years, including patients in the intensive care unit, who received cefepime after admission to a freestanding, tertiary care children’s hospital. Patients were excluded if they were admitted to the neonatal intensive care unit or received cefepime in the outpatient, operating, or ...


Targeted Delivery Of Anti-Inflammatory And Anti-Oxidant Drugs For Treatment Of Chronic Obstructive Pulmonary Diseases, Yun Xiang 2015 Clemson University

Targeted Delivery Of Anti-Inflammatory And Anti-Oxidant Drugs For Treatment Of Chronic Obstructive Pulmonary Diseases, Yun Xiang

All Dissertations

Chronic obstructive pulmonary disease (COPD) was found to be the fourth leading cause of death in 2004, but current treatments can only relieve the symptoms and improve the quality of life for the patients. Glucocorticoids have been broadly applied in other inflammatory conditions with promising therapeutic effects, but performed poorly in COPD. The phenomenon called glucocorticoid resistance is responsible for glucocorticoid insensitivity in COPD. Researchers have proven that elevated oxidative stress in the lung of a COPD patient is one of the main causes of blocking the function of glucocorticoids. We hypothesize that reducing the oxidative stress in the lung ...


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