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Translational Medical Research Commons

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1926 full-text articles. Page 1 of 91.

Messenger Rna And Microrna Transcriptomic Signatures Of Cardiometabolic Risk Factors, David D. McManus, Jian Rong, Tianxiao Huan, Sean Lacey, Kahraman Tanriverdi, Peter J. Munson, Martin G. Larson, Roby Joehanes, Venkatesh Murthy, Ravi Shah, Jane Freedman, Daniel Levy 2017 University of Massachusetts Medical School

Messenger Rna And Microrna Transcriptomic Signatures Of Cardiometabolic Risk Factors, David D. Mcmanus, Jian Rong, Tianxiao Huan, Sean Lacey, Kahraman Tanriverdi, Peter J. Munson, Martin G. Larson, Roby Joehanes, Venkatesh Murthy, Ravi Shah, Jane Freedman, Daniel Levy

David D. McManus

BACKGROUND: Cardiometabolic (CM) risk factors are heritable and cluster in individuals. We hypothesized that CM risk factors are associated with multiple shared and unique mRNA and microRNA (miRNA) signatures. We examined associations of mRNA and miRNA levels with 6 CM traits: body mass index, HDL-cholesterol and triglycerides, fasting glucose, and systolic and diastolic blood pressures through cross-sectional analysis of 2812 Framingham Heart Study who had whole blood collection for RNA isolation for mRNA and miRNA expression studies and who consented to genetic research. We excluded participants taking medication for hypertension, dyslipidemia, or diabetes. We measured mRNA (n = 17,318; using ...


Clinical & Translational Research In Pneumonia: Defining A Research Agenda For Today And Tomorrow, Julio A. Ramirez 2017 University of Louisville

Clinical & Translational Research In Pneumonia: Defining A Research Agenda For Today And Tomorrow, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

From the Editor in Chief

The reason for this special supplement of the Journal is to inform readers of a scientific research conference supported by the National Institutes of Health (NHI). The NIH Research Conference Grant (R13) supports high quality scientific conferences in areas that are important to the NIH's mission and to the public health. We just received notification that the National Heart, Lung, and Blood Institute (NHLBI) has approved the application for an international research conference entitled: DzClinical & Translational Research in Pneumonia: Defining a Research Agenda for Today and Tomorrowdz. The conference will be held on Wednesday ...


Umccts Newsletter, February 2017, UMass Center for Clinical and Translational Science 2017 University of Massachusetts Medical School

Umccts Newsletter, February 2017, Umass Center For Clinical And Translational Science

UMass Center for Clinical and Translational Science Newsletter

This is the February 2017 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.


Umccts Newsletter, January 2017, UMass Center for Clinical and Translational Science 2017 University of Massachusetts Medical School

Umccts Newsletter, January 2017, Umass Center For Clinical And Translational Science

UMass Center for Clinical and Translational Science Newsletter

This is the January 2017 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.


Umccts Newsletter, December 2016, UMass Center for Clinical and Translational Science 2017 University of Massachusetts Medical School

Umccts Newsletter, December 2016, Umass Center For Clinical And Translational Science

UMass Center for Clinical and Translational Science Newsletter

This is the December 2016 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.


Umccts Newsletter, November 2016, UMass Center for Clinical and Translational Science 2017 University of Massachusetts Medical School

Umccts Newsletter, November 2016, Umass Center For Clinical And Translational Science

UMass Center for Clinical and Translational Science Newsletter

This is the November 2016 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.


Umccts Newsletter, October 2016, UMass Center for Clinical and Translational Science 2017 University of Massachusetts Medical School

Umccts Newsletter, October 2016, Umass Center For Clinical And Translational Science

UMass Center for Clinical and Translational Science Newsletter

This is the October 2016 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.


A Novel Hybrid Imaging System To Aid In Surgical Decision Making, Lawrence Yip, Madeleine Van De Kleut, Ivan Kosik, Astrid Chamson-Reig, Jeffrey JL Carson 2017 Western University

A Novel Hybrid Imaging System To Aid In Surgical Decision Making, Lawrence Yip, Madeleine Van De Kleut, Ivan Kosik, Astrid Chamson-Reig, Jeffrey Jl Carson

Western Research Forum

Background:

Breast cancer accounts for 25% of all cancer cases among women. In breast-conserving surgery, a common treatment, the tumour is excised with a healthy tissue margin. However, detection of the margin can be difficult. Current techniques to guide excision are often insufficient, and re-excision can occur up to 25% of the time.

Methods:

Photoacoustic imaging is a hybrid imaging modality that combines the advantages of optical imaging and ultrasound while using safe non-ionizing light. This project involves the development of a novel imaging system with a new scanner design to overcome common limitations and provide images to aid in ...


Youth Outcomes Of Trauma-Focused Cognitive Behavioral Therapy (Tf-Cbt) In The Child Trauma Training Center (Cttc), Crystaltina Montagna, Jessica L. Griffin, Jessica Dym Bartlett, Genevieve Kane-Howse, MaryBeth Todd 2017 University of Massachusetts Medical School

Youth Outcomes Of Trauma-Focused Cognitive Behavioral Therapy (Tf-Cbt) In The Child Trauma Training Center (Cttc), Crystaltina Montagna, Jessica L. Griffin, Jessica Dym Bartlett, Genevieve Kane-Howse, Marybeth Todd

Jessica L. Griffin

Objectives: Exposure to trauma among youth is common and can cause behavioral, social and functioning problems. Use of evidence-based trauma treatment can reduce post-traumatic stress (PTSD) symptoms and behavioral problems. This poster highlights the outcomes of youth who participated in Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) provided by clinicians who were trained through the University of Massachusetts Medical School (UMMS) Child Trauma Training Center (CTTC).

Methods: 308 youth ages 6-18 were enrolled into the CTTC evaluation with a mean age of 11.31 years (SD = 3.5); over half were female (58.1%), the majority were white (62.3%) and 37 ...


Massachusetts Population Health Information Tools: Tools For Community Health Needs Assessment And Planning, Erin Collins, Robert Knorr, Frances Medaglia 2017 Massachusetts Department of Public Health

Massachusetts Population Health Information Tools: Tools For Community Health Needs Assessment And Planning, Erin Collins, Robert Knorr, Frances Medaglia

Community Engagement and Research Symposia

Overview

Staff from the Massachusetts Department of Public Health (MDPH) will conduct a training and discussion on available MDPH data and in-development tools for accessing those data for community engagement, planning and assessment efforts. The workshop will include the sharing of practical information on MDPH data and demonstrations of tools (for those with laptops, hands-on opportunities for data access may be possible).

Learning Objectives

-To learn about available MDPH data and data tools for community engaged research

-To understand possible MDPH roles in community engaged research

- To contribute to MDPH data access planning for meeting the needs of groups conducting ...


Building Collaborative Health Research Drawing On New Lessons From Citizen Science, Linda Silka 2017 University of Maine

Building Collaborative Health Research Drawing On New Lessons From Citizen Science, Linda Silka

Community Engagement and Research Symposia

Community-based participatory research is growing. What is also growing is citizen science. There are useful lessons for the health field from this rapidly growing approach of citizen science. The National Institutes of Health and other health leaders such as Community Campus Partnerships for Health have begun encouraging cross-learning between those engaged in CBPR and those doing citizen science. There are many opportunities to spark innovation and problem solve by analyzing each others’ practices and incorporating relevant aspects into community health research. The purpose of this workshop is to share with participants some of the latest practices in citizen science and ...


Empowering Women In Underserved Communities: Using Cbpr Approaches To Improve Health Literacy And Community Capacity, Jennifer A. Manganello, Janine M. Jurkowski, Elena T. Carbone 2017 University at Albany School of Public Health

Empowering Women In Underserved Communities: Using Cbpr Approaches To Improve Health Literacy And Community Capacity, Jennifer A. Manganello, Janine M. Jurkowski, Elena T. Carbone

Community Engagement and Research Symposia

Moderator: Elena Carbone, DrPH RD, LDN, Associate Professor, Department of Nutrition, UMass Amherst

Presenters:

Jennifer Manganello, MPH, PhD

Janine M. Jurkowski, MPH, PhD

Elena T. Carbone, DrPH, RD, LDN

Session Description

Promoting health literacy empowers individuals and communities to better navigate the health care system and health information environment, and allows for informed decision making for choices and actions that affect health. Empowerment Theory and health literacy are inherent in Community-Based Participatory Research (CBPR) with low-income and disadvantaged populations. In order for representatives to be engaged as equal participants in the research process, research and health capacity building need to ...


Outer Cape Community Resource Navigator Program: Rural Community Engagement-Driven Service Delivery, Andy Lowe, Marta "Dikke" Hansen, Andrew Jorgensen 2017 Outer Cape Health Services

Outer Cape Community Resource Navigator Program: Rural Community Engagement-Driven Service Delivery, Andy Lowe, Marta "Dikke" Hansen, Andrew Jorgensen

Community Engagement and Research Symposia

Moderator: Andy Lowe, Director of Program Management Resources, Outer Cape Health Services

Presenters:

Marta “Dikke” Hansen, MSW, Director of Behavioral Health

Andrew Jorgensen, MD, Associate Medical Director

Session Description

The Outer Cape Cod, Massachusetts region is famed for its beauty as a summer vacation destination. For many residents and migrant workers serving the tourism industry; however, the intersection of isolation, little affordable housing, and limited transportation options can exacerbate problems due to mental health, substance abuse, and co-occurring conditions. Police, emergency responders, and EDs encounter this at-risk population disproportionately. Outer Cape Health Services, the local FQHC, proposed a novel solution ...


The Ethics And Practice Of Digital Storytelling As A Methodology For Community-Based Participatory Research In Public Health, Aline C. Gubrium, Louis F. Graham, Sarah Lowe, Mary Paterno, Alice Fiddian-Green 2017 University of Massachusetts Amherst

The Ethics And Practice Of Digital Storytelling As A Methodology For Community-Based Participatory Research In Public Health, Aline C. Gubrium, Louis F. Graham, Sarah Lowe, Mary Paterno, Alice Fiddian-Green

Community Engagement and Research Symposia

Moderator: Alice Fiddian-Green, PhD student, Department of Health Promotion and Practice, School of Public Health and Health Sciences, University of Massachusetts Amherst.

Presenters and Session Titles:

“An Ethics Framework for Digital Storytelling as a Multi-Purposed Public Health Method”: Aline Gubrium, PhD

Applying the Ethics Framework in Two Projects: (1) Louis Graham, MPH, DrPH, and Sarah Lowe, MPW: “Stakeholder Engagement and Ethical Planning for Digital Storytelling: The MOCHA Moving Forward Project” (2) Mary Paterno, CNM, PhD: “Digital Storytelling as Health Promotion and Data: Ethical Considerations from a Peer-Mentor Based Project to Address Perinatal Substance Use Disorder in a Rural Community"

Session ...


Putting Health Equity Front And Center In Community Health Improvement By Empowering, Listening To, And Respecting Community Voices, Kristin Bafaro, Alexis Travis, Judi Kirk, Ashley Stockwell 2017 Coalition for a Healthy Greater Worcester

Putting Health Equity Front And Center In Community Health Improvement By Empowering, Listening To, And Respecting Community Voices, Kristin Bafaro, Alexis Travis, Judi Kirk, Ashley Stockwell

Community Engagement and Research Symposia

In 2012 the City of Worcester released the first Community Health Improvement Plan (CHIP), with the goal of making Worcester the Healthiest City in the Healthiest Region in the Commonwealth by 2020. Following tremendous success and leveraging lessons learned the Worcester Division of Public health, in collaboration with the Coalition for a Greater Healthy Worcester, UMass Memorial and Fallon Health released the 2016 CHIP, with the single goal of promoting health equity. During this session we will describe the comprehensive needs assessment process, research tools, long-term community engagement strategies and implementation practices that have created a community-driven movement across sectors ...


Project-Based Service Learning Opportunities To Improve Community-Based Services, Meredith Dove 2017 University of Massachusetts Dartmouth

Project-Based Service Learning Opportunities To Improve Community-Based Services, Meredith Dove

Community Engagement and Research Symposia

This presentation was prepared for the breakout session entitled: From the Community to the Classroom: Complementary Pathways to Service Learning and Community Engaged Research.

Students often have a genuine interest in contributing to the local community surrounding UMass Dartmouth through engaged research and learning. This presentation will highlight initiatives to nurture existing university-community partnerships to develop community-based research projects that provide opportunities for student involvement. Project-based service learning opportunities developed through collaboration with community organizations and agencies after identifying organizational needs, often with a goal to strengthen or refine existing services, will be presented. The critical role of institutional support ...


Speaker Biographies: 2017 Community Engagement And Research Symposium, Community Engagement and Research Symposium 2017 University of Massachusetts Medical School

Speaker Biographies: 2017 Community Engagement And Research Symposium, Community Engagement And Research Symposium

Community Engagement and Research Symposia

Biographies of all the speakers at the 6th annual Community Engagement and Research Symposium, held Friday, March 3, 2017 at the University of Massachusetts Medical School, Worcester, MA.


School Based Pediatric Asthma Surveillance In Massachusetts, Frances Medaglia, Vannalyn Abille 2017 Massachusetts Department of Public Health

School Based Pediatric Asthma Surveillance In Massachusetts, Frances Medaglia, Vannalyn Abille

Community Engagement and Research Symposia

Asthma remains one of the most common chronic diseases among children in the United States today. Surveillance is limited to national and state estimates which can vary over time and by population (CDC/NCHS, National Health Interview Survey, 2012). It is estimated that anywhere from 14% to 50% of children with asthma remain undiagnosed. The Massachusetts Department of Public Health's Bureau of Environmental Health (MDPH/BEH) has been conducting a successful and comprehensive statewide school-based asthma surveillance program since 2002. Partnering with school nurses throughout the state, we request aggregate information via a one-page survey. The survey is distributed ...


Chicopee And Springfield School Collaboration With Umass Amherst (Uma): Alcohol And Opioid Screening, Brief Intervention And Referral To Treatment, Donna Zucker, Sally Linowski, Genevieve E. Chandler, Emma Dundon, Gloria DiFulvio, Diane Fedorchak, Suzanne Rataj, Dawn Heffernan 2017 University of Massachusetts - Amherst

Chicopee And Springfield School Collaboration With Umass Amherst (Uma): Alcohol And Opioid Screening, Brief Intervention And Referral To Treatment, Donna Zucker, Sally Linowski, Genevieve E. Chandler, Emma Dundon, Gloria Difulvio, Diane Fedorchak, Suzanne Rataj, Dawn Heffernan

Community Engagement and Research Symposia

The UMA nursing undergraduate training program, SBIRT: The Power of Nursing to Change Health, builds on a SAMHSA curriculum that is integrated into existing psychiatric/mental health, pediatric/young adult and community nursing courses that incorporate alcohol and substance abuse disorders. Student nurses will apply these new skills in their community and medical/surgical rotations in partnership with the Chicopee and Springfield Public Schools. High School survey data indicate that on average 67.5% of high school students have consumed alcohol with 40.1% indicating one drink in the last 30 days, and another 22.2% having five or more ...


Putting Health Equity Front And Center In Community Health Improvement By Empowering, Listening To, And Respecting Community Voices, Alexis Travis, Judi Kirk, Ashley Stockwell, Kristin Bafaro 2017 Worcester Division of Public Health

Putting Health Equity Front And Center In Community Health Improvement By Empowering, Listening To, And Respecting Community Voices, Alexis Travis, Judi Kirk, Ashley Stockwell, Kristin Bafaro

Community Engagement and Research Symposia

In 2016, the Worcester Division of Public Health, Coalition for a Healthy Greater Worcester (CHGW), UMass Memorial and Fallon Health, released the 2016 Community Health Improvement Plan (CHIP). The CHIP spans nine priority areas, with 31 objectives and 100 strategies with measurable outcomes. The focus is on social determinants of health, with health equity as the overarching goal. This goal will only be achieved if we empower, listen to, and respect community voices throughout the CHIP implementation process. CHGW presents a mechanism for community participation. A community-based structure which is open, transparent, and provides support in all areas of implementation ...


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