Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, 2017 Dominican University of California
Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain
Senior Theses and Capstone Projects
Our country’s healthcare system is at a moral crossroads. The way we treat those whom we call “the homeless” is deplorable. The majority of the homeless are mentally ill and need treatment. Our country needs to treat those with the severe brain diseases of schizophrenia, schizo-affective disorder, and bi-polar disorder just as we would Alzheimer’s disease and Parkinson’s disease. Those with severe mental illness, who have no insight into their illness, should not be allowed to dictate their own treatment. If a homeless person is brought to San Francisco General Hospital and is found to be a ...
Inside The Juvenile Justice System, 2016 University of San Francisco
Inside The Juvenile Justice System, Megan Phalon
The United States of America is known for freedom and integrity and being a nation that stands for justice and equality for all. Within the United States there are systems in place to better the people and communities in order to provide safety and order. However, just as any nation, there is a struggle with violent behavior and tendencies among adults and adolescents. Within the last three decades, the United States has created a correctional system that specifically targets adolescents, and that acknowledges the differences between adult and juvenile development and deviant behavior. Within this literature review, academic databases were ...
Into The Light: Using Technology To Develop A Mother/Family Centered Peer Support Network, 2016 Postpartum Progress Inc.
Into The Light: Using Technology To Develop A Mother/Family Centered Peer Support Network, Shannon Hennig, Katherine Stone, Joanne Nicholson
Journal of Parent and Family Mental Health
This paper highlights the work of Postpartum Progress Inc., to engage with large online communities of women experiencing a perinatal mental health issue, in order to explore the efficacy of peer support as a treatment modality. "Into the Light" is a Patient Centered Outcomes Research Institute (PCORI) Pipeline to Proposal project that will bring together diverse stakeholders and patients to build collaborative partnerships. Project goals include developing patient engagement, recruitment and dissemination strategies that reflect the needs of this patient population. Increasing patient access to easily understood information about treatment options when making health care decisions and improving patient-centered research ...
Physical Multimorbidity And Psychosis: Comprehensive Cross Sectional Analysis Including 242,952 People Across 48 Low- And Middle-Income Countries, Brendon Stubbs, Ai Koyanagi, Nicola Veronese, Davy Vancampfort, Marco Solmi, Fiona Gaughran, Andre Carvalho, John Lally, Alex J. Mitchell, James Mugisha, Christoph U. Correll
In people with psychosis, physical comorbidities, including cardiovascular and metabolic diseases, are highly prevalent and leading contributors to the premature mortality encountered. However, little is known about physical health multimorbidity in this population or in people with subclinical psychosis and in low- and middle-income countries (LMICs). This study explores physical health multimorbidity patterns among people with psychosis or subclinical psychosis.
Overall, data from 242,952 individuals from 48 LMICs, recruited via the World Health Survey, were included in this cross-sectional study. Participants were subdivided into those (1) with a lifetime diagnosis of psychosis (“psychosis”); (2) with more than ...
Evaluation Of Patient Opinions And Experiences With Electronic Cigarettes At A Family Medicine Residency Clinic, Ima D. Tanner, Breana C. Cummens, Jessica J.F. Kram, Dennis J. Baumgardner
Journal of Patient-Centered Research and Reviews
Background: Since 2003, electronic cigarettes (e-cigs) have grown in popularity. E-cigs are often marketed as a safer, healthier alternative to smoking traditional cigarettes or as an aid for smoking cessation. However, the risks and benefits of e-cig use, as well as the beliefs that influence use or avoidance, are poorly understood.
Purpose: To assess our patient population’s perception or beliefs as they relate to e-cig use.
Methods: A 13-question survey regarding nicotine and e-cig use was distributed to English-speaking adult patients at Aurora St. Luke’s Family Practice Clinic from August 2015 to January 2016. Questions assessed patient demographics ...
Oxytocin’S Effects On Sickness Behaviours, Anxiety Responses, And Immune Function In Adult Male Mice, 2016 The University of Western Ontario
Oxytocin’S Effects On Sickness Behaviours, Anxiety Responses, And Immune Function In Adult Male Mice, Julie Deleemans
Electronic Thesis and Dissertation Repository
The nonapeptide, oxytocin (OT), is implicated in a range of behavioural and physiological functions. However, OT's role in sickness behaviours remains unclear. This thesis examined effects of the OT agonist, carbetocin (CBT), and OT antagonist, L-368,899, on anxiety and locomotor sickness-related behaviours and pro-inflammatory cytokines, TNF-a and IL-6, in adult male CD-1 mice. Animals received 2 intraperitoneal treatment injections. The first treatment was carbetocin, L-368,899, or saline, while the second was lipopolysaccharide (LPS) or saline. Behaviours were evaluated via the light-dark test, and cytokines via immunoassay. OT antagonist treatment attenuated LPS induced perturbations in locomotor and ...
Treatment-Resistant Schizophrenia: Current Insights On The Pharmacogenomics Of Antipsychotics, 2016 Royal College of Surgeons in Ireland
Treatment-Resistant Schizophrenia: Current Insights On The Pharmacogenomics Of Antipsychotics, John Lally, Fiona Gaughran, Philip Timms, Sarah R. Curran
Up to 30% of people with schizophrenia do not respond to two (or more) trials of dopaminergic antipsychotics. They are said to have treatment-resistant schizophrenia (TRS). Clozapine is still the only effective treatment for TRS, although it is underused in clinical practice. Initial use is delayed, it can be hard for patients to tolerate, and clinicians can be uncertain as to when to use it. What if, at the start of treatment, we could identify those patients likely to respond to clozapine – and those likely to suffer adverse effects? It is likely that clinicians would feel less inhibited about using ...
Randomized Trial Of A Pharmacist-Delivered Intervention For Improving Lipid-Lowering Medication Adherence Among Patients With Coronary Heart Disease, 2016 University of Massachusetts Medical School
Randomized Trial Of A Pharmacist-Delivered Intervention For Improving Lipid-Lowering Medication Adherence Among Patients With Coronary Heart Disease, Yunsheng Ma, Ira S. Ockene, Milagros C. Rosal, Philip A. Merriam, Judith K. Ockene, Pritesh J. Gandhi
Ira S. Ockene
A randomized trial of a pharmacist-delivered intervention (PI) versus usual care (UC) was conducted; 689 subjects with known coronary heart disease were recruited from cardiac catheterization laboratories. Participants in the PI condition received 5 pharmacist-delivered telephone counseling calls post-hospital discharge. At one year, 65% in the PI condition and 60% in the UC condition achieved an LDL-C level <100 mg/dL (P=.29); mean statin adherence was 0.88 in the PI, and 0.90 in the UC (P=.51). The highest percentage of those who reached the LDL-C goal were participants who used statins as opposed to those who did not use statins (67% versus 58%, P=.05). However, only 53% and 56% of the patients in the UC and PI conditions, respectively, were using statins. We conclude that a pharmacist-delivered intervention aimed only at improving patient adherence is unlikely to positively affect outcomes. Efforts must be oriented towards influencing physicians to increase statin prescription rates.
Methodology Of A Diabetes Prevention Translational Research Project Utilizing A Community-Academic Partnership For Implementation In An Underserved Latino Community, 2016 University of Massachusetts Medical School
Methodology Of A Diabetes Prevention Translational Research Project Utilizing A Community-Academic Partnership For Implementation In An Underserved Latino Community, Philip A. Merriam, Trinidad Tellez, Milagros C. Rosal, Barbara C. Olendzki, Yunsheng Ma, Sherry L. Pagoto, Ira S. Ockene
Ira S. Ockene
BACKGROUND: Latinos comprise the largest racial/ethnic group in the United States and have 2-3 times the prevalence of type 2 diabetes mellitus as Caucasians.
METHODS AND DESIGN: The Lawrence Latino Diabetes Prevention Project (LLDPP) is a community-based translational research study which aims to reduce the risk of diabetes among Latinos who have a >/= 30% probability of developing diabetes in the next 7.5 years per a predictive equation. The project was conducted in Lawrence, Massachusetts, a predominantly Caribbean-origin urban Latino community. Individuals were identified primarily from a community health center's patient panel, screened for study eligibility, randomized to ...
Methodological Limitations Of Psychosocial Interventions In Patients With An Implantable Cardioverter-Defibrillator (Icd) A Systematic Review., 2016 University of Massachusetts Medical School
Methodological Limitations Of Psychosocial Interventions In Patients With An Implantable Cardioverter-Defibrillator (Icd) A Systematic Review., Elena Salmoirago Blotcher, Ira S. Ockene
Ira S. Ockene
BACKGROUND: Despite the potentially life-saving benefits of the implantable cardioverter-defibrillator (ICD), a significant group of patients experiences emotional distress after ICD implantation. Different psychosocial interventions have been employed to improve this condition, but previous reviews have suggested that methodological issues may limit the validity of such interventions.
AIM: To review the methodology of previously published studies of psychosocial interventions in ICD patients, according to CONSORT statement guidelines for non-pharmacological interventions, and provide recommendations for future research.
METHODS: We electronically searched the PubMed, PsycInfo and Cochrane databases. To be included, studies needed to be published in a peer-reviewed journal between 1980 ...
Design And Methods For Testing A Simple Dietary Message To Improve Weight Loss And Dietary Quality, 2016 University of Massachusetts Medical School
Design And Methods For Testing A Simple Dietary Message To Improve Weight Loss And Dietary Quality, Philip A. Merriam, Yunsheng Ma, Barbara C. Olendzki, Kristin L. Schneider, Wenjun Li, Ira S. Ockene, Sherry L. Pagoto
Ira S. Ockene
BACKGROUND: The current food pyramid guidelines have been criticized because of their complexity and the knowledge required for users to understand the recommendations. Simplification of a dietary message to focus on a single key aspect of dietary quality, e.g., fiber intake, may make the message much easier to comprehend and adhere, such that respondents can achieve greater weight loss, better dietary quality and overall metabolic health.
METHODS AND DESIGN: This is a randomized controlled clinical trial with two equal sized arms. In total, 240 obese adults who meet diagnostic criteria for the metabolic syndrome will be randomized to one ...
Association Between Depression And C-Reactive Protein, 2016 University of Massachusetts Medical School
Association Between Depression And C-Reactive Protein, Yunsheng Ma, David E. Chiriboga, Sherry L. Pagoto, Milagros C. Rosal, Wenjun Li, Philip A. Merriam, James R. Hebert, Matthew Whited, Ira S. Ockene
Ira S. Ockene
Objective: Depression has been associated with increased cardiovascular disease risk, and a depression–related elevation of high sensitivity C-reactive protein (hs-CRP) has been proposed as a possible mechanism. The objective of this study was to examine association between 27 depression and high sensitivity C-reactive protein (hs-CRP).
Methods: Subjects consisted of 508 healthy adults (mean age 48.5 years; 49% women, 88% white) residing in central Massachusetts. Data were collected at baseline and at quarterly intervals over a one-year period per individual. Multivariable linear mixed models were used to assess the association for the entire sample and by gender.
Results: The ...
Associations Of Daily Eating Episodes, And Eating Away-From-Home With Blood Level Of Total Cholesterol, 2016 University of Massachusetts Medical School
Associations Of Daily Eating Episodes, And Eating Away-From-Home With Blood Level Of Total Cholesterol, Yunsheng Ma, Elizabeth R. Bertone-Johnson, Edward J. Stanek, Nancy L. Cohen, Ira S. Ockene
Ira S. Ockene
The objective of this investigation is to describe the associations of number of eating episodes and proportion of meals eaten away from home with total serum cholesterol. Data from 499 participants, recruited from a health maintenance organization in central Massachusetts, aged 20-70, were used for this analysis. Dietary information and total blood cholesterol were obtained at five sampling points (baseline and four consecutive quarters) during the one-year follow-up. A cross-sectional study was conducted. The results from the study do not support the hypothesis that the number of eating episodes per day is associated with total blood cholesterol. However, we noted ...
A Study On Situational Awareness Security And Privacy Of Wearable Health Monitoring Devices, 2016 Abertay University
A Study On Situational Awareness Security And Privacy Of Wearable Health Monitoring Devices, Xavier Bellekens
Clinical Impact Of A Novel Interprofessional Dental And Pharmacy Student Tobacco Cessation Education Program On Dental Patients, Matthew Boyd, Pharmd Candidate, Jillian Lykon, Pharmd Candidate, Jacqueline M. Theodorou, Pharmd, Bcps, Melissa E. Rotz, Pharmd, Bcps, Shannon Myers Virtue, Psyd, Elizabeth Waldron, Ba
• To compare the difference between IPE care and standard care (SC) groups regarding dental patients' perceptions of knowledge gained about tobacco cessation, intentions to quit tobacco use, and quit attempts at follow-up.
• To evaluate perceptions of IPE care.
Based on the link between tobacco use and oral health and the frequent contact between dental providers and patients, the dental clinic is an ideal setting to address tobacco use.1
• Many dentists feel unprepared providing tobacco cessation education, particularly pharmacologic treatment options.1-3
• Pharmacists promote safe and effective pharmacologic treatment options for tobacco dependence and patients’ perceptions toward pharmacist-provided ...
Systematic Development Of Trans-Theoretically Based Behavioral Risk Management Programs, 2016 University of New Hampshire
Systematic Development Of Trans-Theoretically Based Behavioral Risk Management Programs, Galen E. Cole, David R. Holtgrave, Nilka M. Rios
RISK: Health, Safety & Environment
The authors explain the development and use of a behavioral Risk management strategy. It is designed for developing interventions to change behaviors, e.g., to lower the Risk of AIDS. The advantage of their strategy is said to be its structure combined with flexibility. Intervenors are not restricted to a single model in determining factors most relevant to changing Risky behavior.
Improving Mental Health Of Elementary School Children, 2016 Purdue University
Improving Mental Health Of Elementary School Children, Alexa Proctor
Purdue Journal of Service-Learning and International Engagement
Alexa Proctor is an advanced practice student on clinical rotations with the Purdue University College of Pharmacy. In this article, she describes her experience working with Mental Health America (MHA) of Tippecanoe County and third grade children, in addition to her passion to help improve mental health in students of all ages.
Book Review, 2016 University of New Hampshire
Book Review, Juanita V. Field
RISK: Health, Safety & Environment
Review of the following: Risk-TAKING BEHAVIOR. (J. Frank Yates, ed., Wiley 1992) [244 pp.] Acknowledgements, author index, figures, preface, references, series preface, subject index, tables. LC 91-21229, ISBN 0-471-92250-1. [Cloth $64.95. 1 Wiley Drive, Somerset NJ 08875.
Individual Response To Risk As A Function Of Normative Social Pressure: A Pilot Study Of Seat Belt Use, 2016 University of New Hampshire
Individual Response To Risk As A Function Of Normative Social Pressure: A Pilot Study Of Seat Belt Use, Kenneth D. Boehm, John T. Keating, Karl W. Pfefferkorn, Audra J. Pfeltz, Brady G. Serafin, Jessica L. Sullivan, Karen L. Thode, Kevin M. Vincent, Juanita V. Field
RISK: Health, Safety & Environment
The authors attempt to clarify some of the variables that influence whether people act appropriately when a Risk is substantial and subject to individual control. They do so by reporting results of a pilot study of seat belt use. Also, the authors believe their approach to be generalizable to problems such as encouraging people to test for radon, to use condoms to prevent AIDS or to quit smoking.