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Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain 2017 Dominican University of California

Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain

Senior Theses and Capstone Projects

Our country’s healthcare system is at a moral crossroads. The way we treat those whom we call “the homeless” is deplorable. The majority of the homeless are mentally ill and need treatment. Our country needs to treat those with the severe brain diseases of schizophrenia, schizo-affective disorder, and bi-polar disorder just as we would Alzheimer’s disease and Parkinson’s disease. Those with severe mental illness, who have no insight into their illness, should not be allowed to dictate their own treatment. If a homeless person is brought to San Francisco General Hospital and is found to be a ...


Inside The Juvenile Justice System, Megan Phalon 2016 University of San Francisco

Inside The Juvenile Justice System, Megan Phalon

Master's Projects

The United States of America is known for freedom and integrity and being a nation that stands for justice and equality for all. Within the United States there are systems in place to better the people and communities in order to provide safety and order. However, just as any nation, there is a struggle with violent behavior and tendencies among adults and adolescents. Within the last three decades, the United States has created a correctional system that specifically targets adolescents, and that acknowledges the differences between adult and juvenile development and deviant behavior. Within this literature review, academic databases were ...


Depression Treatment Decreases Healthcare Expenditures Among Working Age Patients With Comorbid Conditions And Type 2 Diabetes Mellitus Along With Newly-Diagnosed Depression, Rituparna Bhattacharya, Chan Shen, Amy B. Wachholtz, Nilanjana Dwibedi, Usha Sambamthoori 2016 Humana, Inc.

Depression Treatment Decreases Healthcare Expenditures Among Working Age Patients With Comorbid Conditions And Type 2 Diabetes Mellitus Along With Newly-Diagnosed Depression, Rituparna Bhattacharya, Chan Shen, Amy B. Wachholtz, Nilanjana Dwibedi, Usha Sambamthoori

Amy B. Wachholtz

BACKGROUND: There are many studies in the literature on the association between depression treatment and health expenditures. However, there is a knowledge gap in examining this relationship taking into account coexisting chronic conditions among patients with diabetes. We aim to analyze the association between depression treatment and healthcare expenditures among adults with Type 2 Diabetes Mellitus (T2DM) and newly-diagnosed depression, with consideration of coexisting chronic physical conditions.

METHODS: We used multi-state Medicaid data (2000-2008) and adopted a retrospective longitudinal cohort design. Medical conditions were identified using diagnosis codes (ICD-9-CM and CPT systems). Healthcare expenditures were aggregated for each month for ...


Visual Perception And Processing In Children With 22q11.2 Deletion Syndrome: Associations With Social Cognition Measures Of Face Identity And Emotion Recognition., Kathryn L. McCabe, Stuart Marlin, Gavin Cooper, Robin Morris, Ulrich Schall, Declan G. Murphy, Kieran C. Murphy, Linda E. Campbell 2016 The University of Newcastle, Australia

Visual Perception And Processing In Children With 22q11.2 Deletion Syndrome: Associations With Social Cognition Measures Of Face Identity And Emotion Recognition., Kathryn L. Mccabe, Stuart Marlin, Gavin Cooper, Robin Morris, Ulrich Schall, Declan G. Murphy, Kieran C. Murphy, Linda E. Campbell

Psychiatry Articles

BACKGROUND: People with 22q11.2 deletion syndrome (22q11DS) have difficulty processing social information including facial identity and emotion processing. However, difficulties with visual and attentional processes may play a role in difficulties observed with these social cognitive skills.

METHODS: A cross-sectional study investigated visual perception and processing as well as facial processing abilities in a group of 49 children and adolescents with 22q11DS and 30 age and socio-economic status-matched healthy sibling controls using the Birmingham Object Recognition Battery and face processing sub-tests from the MRC face processing skills battery.

RESULTS: The 22q11DS group demonstrated poorer performance on all measures of ...


Muscle Dysmorphia And Athletic Identity, Taylor McGohan 2016 Western Kentucky University

Muscle Dysmorphia And Athletic Identity, Taylor Mcgohan

Honors College Capstone Experience/Thesis Projects

Society is creating a stronger importance for men to have muscular physiques. Therefore, increasing the dissatisfaction men have with their bodies and perceptions of body image. The current study assesses the possible relationship between muscle dysmorphia and athletic identity. As well as a relationship between lifting time and athletic identity. Participants for the current study took three different self-reported surveys to measure demographics, exercise history, level of athletic identity, and possible symptoms of muscle dysmorphia. It was hypothesized that those with strong athletic identities also have a stronger desire to gain muscle mass, increasing likelihood of displaying muscle dysmorphia symptoms ...


Cal And Magi Pdz Protein Regulation Of Crfr1 And 5-Ht2ar Trafficking And Signaling, Maha Mahmoud Hammad 2016 The University of Western Ontario

Cal And Magi Pdz Protein Regulation Of Crfr1 And 5-Ht2ar Trafficking And Signaling, Maha Mahmoud Hammad

Electronic Thesis and Dissertation Repository

PDZ (PSD95/Disc Large/Zona Occludens) domain-containing proteins are scaffolding proteins that play important roles in regulating the activity of G protein-coupled receptors. Corticotropin Releasing Factor Receptor 1 (CRFR1) and Serotonin 2A Receptor (5-HT2AR) are two GPCRs that are commonly associated with mental disorders. Both receptors also contain a class I PDZ-binding motif at the carboxyl terminal tail. In the first chapter, we investigate the effects of CAL (CFTR-associated ligand) on regulating the trafficking and signaling of CRFR1. We demonstrate a role for CAL in inhibiting CRFR1 endocytosis, cell surface expression, and CRF-mediated ERK1/2 signaling via the ...


Barriers And Facilitators To Deaf Trauma Survivors’ Help-Seeking Behavior: Lessons For Behavioral Clinical Trials Research: A Master’S Thesis, Melissa L. Anderson 2016 University of Massachusetts Medical School

Barriers And Facilitators To Deaf Trauma Survivors’ Help-Seeking Behavior: Lessons For Behavioral Clinical Trials Research: A Master’S Thesis, Melissa L. Anderson

Melissa L. Anderson

Deaf individuals experience significant obstacles to participating in behavioral health research when careful consideration is not given to accessibility in the design of study methodology. To inform such considerations, we conducted a secondary analysis of a mixed-methods study that explored 16 Deaf trauma survivors’ help-seeking experiences. Our objective was to identify key findings and qualitative themes from consumers' own words that can be applied to the design of behavioral clinical trials methodology. In many ways, the themes that emerged are what we would expect of any research participant, Deaf or hearing – a need for communication access, empathy, respect, strict confidentiality ...


How Best To Study For A Test: A Comparison Of Practice Retrieval And Self-Explanation, Casey Fortney 2016 Western Kentucky University

How Best To Study For A Test: A Comparison Of Practice Retrieval And Self-Explanation, Casey Fortney

Honors College Capstone Experience/Thesis Projects

Students often struggle to prepare for their exams, perhaps as a result of using an unhelpful study method. This study compared the effects of using three study methods: rereading, practice retrieval, and self-explanation. 79 college students studied a short science text passage and were tested with both verbatim and inference questions one week later. Students who reread the information did not perform differently from those who practiced retrieving or self-explained the information. Students who self-explained the information performed better on verbatim test questions than those who practiced retrieving the information. Possible explanations for these findings and implications are discussed.


Non-Suicidal Self-Injury, Suicidal Behaviors, And Body Investment In Heterosexual And Sexual Minority Young Adults, Emily Cox 2016 Western Kentucky University

Non-Suicidal Self-Injury, Suicidal Behaviors, And Body Investment In Heterosexual And Sexual Minority Young Adults, Emily Cox

Honors College Capstone Experience/Thesis Projects

College-aged individuals who identify with a sexual minority orientation are at high risk for non-suicidal self-injury (NSSI) and suicidal behaviors. Research is lacking on identification of factors contributing to increased risk for this population. This study examined two facets of body investment, body protection and body feelings, as they relate to NSSI, individual and total suicidal behaviors, and sexual orientation. It was hypothesized that NSSI and individual suicidal behaviors would be more frequent in the sexual minority sample compared to the heterosexual sample, body protection and body feelings would be poorer in sexual minorities compared to the heterosexual sample, and ...


Cultural Diversity And The Impact Of Acculturation And Personal Experience On Perceptions Of Suicide, Susan Breidenich 2016 Western Kentucky University

Cultural Diversity And The Impact Of Acculturation And Personal Experience On Perceptions Of Suicide, Susan Breidenich

Honors College Capstone Experience/Thesis Projects

Many factors influence cross-cultural differences in suicide rates and behaviors. One potential explanation is that attitudes and values influence the way individuals perceive suicide. In addition, previous literature indicates that attitudes can change in response to individual experiences. Further research on cultural attitudes toward suicide and individual experiences that influence them could inform prevention and treatment efforts targeted toward multicultural populations. The aim of this study is to examine the impact of culture, acculturation, and personal experience (i.e., exposure to suicidal behavior through close relationship) on suicide attitudes. The hypotheses were (1) that significant differences in attitudes towards suicide ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Tiffany A. Moore Simas

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Jeroan J. Allison

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar 2016 University of Massachusetts Medical School

Association Of Common Mental Disorder Symptoms With Health And Healthcare Factors Among Women In Rural Western India: Results Of A Cross-Sectional Survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, Somashekhar Nimbalkar

Nancy Byatt

OBJECTIVES: Information about common mental disorders (CMD) is needed to guide policy and clinical interventions in low-income and middle-income countries. This study's purpose was to characterise the association of CMD symptoms with 3 inter-related health and healthcare factors among women from rural western India based on a representative, cross-sectional survey.

SETTING: Surveys were conducted in the waiting area of various outpatient clinics at a tertiary care hospital and in 16 rural villages in the Anand district of Gujarat, India.

PARTICIPANTS: 700 Gujarati-speaking women between the ages of 18-45 years who resided in the Anand district of Gujarat, India, were ...


Piloting Signs Of Safety: A Deaf-Accessible Toolkit For Trauma And Addiction, Melissa L. Anderson, Kelly S. Wolf Craig, Amanda Sortwell, Douglas M. Ziedonis 2016 University of Massachusetts Medical School

Piloting Signs Of Safety: A Deaf-Accessible Toolkit For Trauma And Addiction, Melissa L. Anderson, Kelly S. Wolf Craig, Amanda Sortwell, Douglas M. Ziedonis

Douglas M. Ziedonis

The Deaf community - a minority group of 500,000 Americans who use American Sign Language (ASL) - experiences trauma and addiction at rates double to the general population. Yet, there are no evidence-based treatments that have been evaluated to treat trauma, addiction, or other behavioral health conditions among Deaf people. Current evidence-based treatments fail to meet the needs of Deaf clients. One example is Seeking Safety, a well-validated therapy for people recovering from trauma and addiction. Seeking Safety includes a therapist guide and client handouts for 25 therapy sessions, each teaching clients a safe coping skill. When Seeking Safety was used ...


Evaluation Of Tobacco Use On Chinese Population Through Attoc Model: A Cross-Sectional Survey On Hospitalized Psychiatric Patients, Xue Wang, Zugui Peng, Douglas M. Ziedonis, Chaomin Wang, Bo Yu, Tao Li 2016 Sichuan University

Evaluation Of Tobacco Use On Chinese Population Through Attoc Model: A Cross-Sectional Survey On Hospitalized Psychiatric Patients, Xue Wang, Zugui Peng, Douglas M. Ziedonis, Chaomin Wang, Bo Yu, Tao Li

Douglas M. Ziedonis

OBJECTIVES: To evaluate the feasibility of Addressing Tobaccos through Organizational Change (ATTOC) intervention to Chinese psychiatric patients, and to better address tobacco use through the ATTOC intervention model in the context of China.

METHODS: The study was conducted in Mental Health Center of West China Hospital in 2010. A total of 100 hospitalized psychiatric patients were recruited to carry out ATTOC intervention. Subjects suffers from mental illness were diagnosed by professional psychiatrists according to the International Statistical Classification of Diseases (ICD-10) criteria.

RESULTS: The prevalence of tobacco use in hospitalized psychiatric patients were closely correlated with the type of mental ...


A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis 2016 University of Massachusetts Boston

A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis

Douglas M. Ziedonis

Introduction: Korean American women prefer online or telephone smoking cessation interventions that can be remotely accessed from home. However, these interventions have been found ineffective for the group.

Methods: This study is a pilot clinical trial testing the feasibility and acceptability of a videoconferencing smoking cessation intervention for Korean American women and compared its preliminary efficacy with a telephone-based smoking cessation intervention. Korean women in the United States were recruited nationwide and randomly assigned at a ratio of 1:1 to either a video arm or a telephone arm. Participants in both arms received eight 30-minute weekly individualized counseling sessions ...


A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis 2016 University of Massachusetts Boston

A Pilot Randomized Controlled Trial Of A Videoconferencing Smoking Cessation Intervention For Korean American Women: Preliminary Findings, Sun S. Kim, Somporn Sitthisongkram, Kunsook Bernstein, Hua (Julia) Fang, Won S. Choi, Douglas M. Ziedonis

Hua Julia Fang

Introduction: Korean American women prefer online or telephone smoking cessation interventions that can be remotely accessed from home. However, these interventions have been found ineffective for the group.

Methods: This study is a pilot clinical trial testing the feasibility and acceptability of a videoconferencing smoking cessation intervention for Korean American women and compared its preliminary efficacy with a telephone-based smoking cessation intervention. Korean women in the United States were recruited nationwide and randomly assigned at a ratio of 1:1 to either a video arm or a telephone arm. Participants in both arms received eight 30-minute weekly individualized counseling sessions ...


Adapting Behavioral Interventions For Social Media Delivery, Sherry L. Pagoto, Molly E. Waring, Christine N. May, Eric Y. Ding, Werner H. Kunz, Rashelle B. Hayes, Jessica L. Oleski 2016 University of Massachusetts Medical School

Adapting Behavioral Interventions For Social Media Delivery, Sherry L. Pagoto, Molly E. Waring, Christine N. May, Eric Y. Ding, Werner H. Kunz, Rashelle B. Hayes, Jessica L. Oleski

Molly E. Waring

Patients are increasingly using online social networks (ie, social media) to connect with other patients and health care professionals--a trend called peer-to-peer health care. Because online social networks provide a means for health care professionals to communicate with patients, and for patients to communicate with each other, an opportunity exists to use social media as a modality to deliver behavioral interventions. Social media-delivered behavioral interventions have the potential to reduce the expense of behavioral interventions by eliminating visits, as well as increase our access to patients by becoming embedded in their social media feeds. Trials of online social network-delivered behavioral ...


Multiple Chronic Conditions And Psychosocial Limitations In A Contemporary Cohort Of Patients Hospitalized With An Acute Coronary Syndrome, Mayra Tisminetsky, Jerry H. Gurwitz, David D. McManus, Jane S. Saczynski, Molly E. Waring, Nathaniel Erskine, Milena D. Anatchkova, David C. Parish, Darleen M. Lessard, Catarina I. Kiefe, Robert J. Goldberg 2016 University of Massachusetts Medical School

Multiple Chronic Conditions And Psychosocial Limitations In A Contemporary Cohort Of Patients Hospitalized With An Acute Coronary Syndrome, Mayra Tisminetsky, Jerry H. Gurwitz, David D. Mcmanus, Jane S. Saczynski, Molly E. Waring, Nathaniel Erskine, Milena D. Anatchkova, David C. Parish, Darleen M. Lessard, Catarina I. Kiefe, Robert J. Goldberg

Molly E. Waring

Background: As adults live longer, multiple chronic conditions have become more prevalent over the past several decades. We describe the prevalence of, and patient characteristics associated with, cardiac and non-cardiac-related multimorbidities in patients discharged from the hospital after an acute coronary syndrome (ACS).

Methods: We studied 2,174 patients discharged from the hospital after an ACS at 6 medical centers in Massachusetts and Georgia between April, 2011 and May, 2013. Hospital medical records yielded clinical information including presence of 8 cardiac-related and 8 non-cardiac-related morbidities on admission. We assessed multiple psychosocial characteristics during the index hospitalization using standardized in-person instruments ...


A Non-Restrictive Weight Loss Diet Focused On Increasing Fiber And Lean Protein: Results Of A Pilot Trial, Lijuan Zhang, Sherry L. Pagoto, Barbara C. Olendzki, Gioia Persuitte, Linda C. Churchill, Jessica Oleski, Yunsheng Ma 2016 University of Massachusetts Medical School

A Non-Restrictive Weight Loss Diet Focused On Increasing Fiber And Lean Protein: Results Of A Pilot Trial, Lijuan Zhang, Sherry L. Pagoto, Barbara C. Olendzki, Gioia Persuitte, Linda C. Churchill, Jessica Oleski, Yunsheng Ma

Sherry L. Pagoto

Objective. The vast majority of diets are not only multicomponent but also restrictive. Dietary fiber or protein can reduce hunger and enhance satiety; they also exert clinical benefits. We examined feasibility and acceptability of a non-restrictive diet combining the two for weight loss.

Population and Methods. Fifteen patients were enrolled in the trial (2 men, 13 women, mean age=48 y and mean BMI = 36 kg/m2) to attend 6 bi-weekly individual counselling sessions for the diet during the 12-week study period. The goals of the intervention were to attain a daily goal of higher fiber (>35g)/ and lean protein ...


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