Characterizing The Response Of Multidrug-Resistant Klebsiella Pneumoniae Species To The Application Of A Phage Cocktail, 2014 California Polytechnic State University
Characterizing The Response Of Multidrug-Resistant Klebsiella Pneumoniae Species To The Application Of A Phage Cocktail, Steven Liu
Project Summary: The application of bacteriophages to treat bacterial infections is known as phage therapy, which takes advantage of bacteriophage’s natural ability to infect and lyse bacterial hosts. Phages have been shaped by billions of years of evolution to be highly specialized deliverers of bactericidal agents to the cytoplasm of their target bacteria. Ever since discovery of bacteriophages in 1915, phage therapy was recognized as a potentially powerful tool for eliminating bacterial infections. The effectiveness of phage therapy can be increased by creating a mixture of multiple phages to target a wider variety of bacterial strains. Furthermore, phage therapy ...
Informed Consent, Psychotropic Medications, And A Prescribing Physician’S Duty To Disclose Safer Alternative Treatments, 2014 Chapman University Dale E. Fowler School of Law
Informed Consent, Psychotropic Medications, And A Prescribing Physician’S Duty To Disclose Safer Alternative Treatments, Rita F. Barnett Ms.
INFORMED CONSENT, PSYCHOTROPIC MEDICATIONS, AND A PRESCRIBING PHYSICIAN’S DUTY TO DISCLOSE SAFER ALTERNATIVE TREATMENTS
The use of psychotropic medication to treat any presumed mental health disorder always involves serious risks of harm. Accordingly, before prescribing psychotropic medication to control the behaviors associated with a presumed mental health disorder, prescribing physicians are required, under various medical ethical guidelines and informed consent laws, to first disclose information regarding available alternative treatment options, and the risks and benefits of such alternative treatment options. Indeed, because psychotropic medications are themselves experimental treatments due to the concededly unknown etiology of most mental health disorders ...
The Use Of Natural Products As Potential Anti-Pseudomonas Agents, 2014 Seton Hall University
The Use Of Natural Products As Potential Anti-Pseudomonas Agents, Margaret T. Bell
Seton Hall University Dissertations and Theses (ETDs)
Pseudomonas is a genus of gram-negative gammaproteobacteria with a large range of diversity. Because of its ability to grow at low temperature, Pseudomonas is a cause of food spoilage. This bacterium is also a very common nosocomial infection of hospital patients. In this study, we investigated the effects of different natural products on Pseudomonas. The products included a polysaccharide, two flavonoids tangeretin and nobiletin and their derivatives, 5’OH-tangeretin and 5’OH-nobiletin, black tea polyphenol – theaflavins (TFs), as well as an herb named Fallopia multiflora (Chinese Knotweed). P. fluorescens and P. aeruginosa were used as model organisms. Antimicrobial effects were ...
Herbal And Holistic Medicine In Latin America, 2014 Western Kentucky University
Herbal And Holistic Medicine In Latin America, William H. Lyle
Honors College Capstone Experience/Thesis Projects
A variety of herbal and holistic remedies were used in pre-Columbian cultures, especially in Aztec and Incan cultures. Many different herbs were used to provide medical attention to patients directly, while other herbs were used to supplement shaman medicine, which was particularly common in Inca culture. While there is little scientific basis for shamanism, as a viable healing option in modern culture, most herbal remedies had active chemical ingredients that could be or are used today to treat similar symptoms, and, in some cases, are being applied in different scenarios as well. The methods of usage, active chemicals, and ...
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, 2014 University of Connecticut
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn
Honors Scholar Theses
Substantial evidence has shown that dopamine (DA), particularly in the nucleus accumbens (NAc), is involved in behavioral activation and effort-related processes, such as overcoming work related response costs. Interference with accumbens DA transmission through administration of the vesicular monoamine transportor-2 (VMAT-2) inhibitor tetrabenazine (TBZ) produces an alteration of response allocation in the concurrent FR5/chow choice procedure, biasing animals toward the lower effort alternative. It has been suggested that these drug-induced shifts in effort-related choice behavior seen in rodents are analogous to symptoms such as psychomotor retardation, anergia, and fatigue, which can be observed in people with depression and other ...
Cultural Competency In The Medical Workplace: A Look At Outpatient Clinic Nurses At A Children's Hospital In New England, 2014 University of Connecticut
Cultural Competency In The Medical Workplace: A Look At Outpatient Clinic Nurses At A Children's Hospital In New England, Evelyn S. Callahan
Honors Scholar Theses
This paper analyzes the current state of progress toward cultural competency in the medical workplace, specifically in the hospital setting. It compares the current writing on the topic to research done at a large New England children’s hospital. The nurses are all individuals who work in an out patient setting so they often see the same patients regularly for longer periods of time. This differs from the in-patient or floor nurses who only spend limited time with a constantly changing population of patients. The research involved one-on-one interviews and a focus group with nurses at the hospital. The focus ...
Effect Of Ascorbate On Coagulation And Fibrinolytic Factors In The Septic Microvasculature, 2014 Western University
Effect Of Ascorbate On Coagulation And Fibrinolytic Factors In The Septic Microvasculature, Scott Swarbreck
University of Western Ontario - Electronic Thesis and Dissertation Repository
Sepsis, a systemic inflammatory response to an infection, is a significant cause of morbidity and mortality worldwide. The microcirculation during sepsis fails, in part, due to microthrombosis and the resulting plugging of capillaries, precipitating organ failure. Intravenous injection of ascorbate has been shown to reduce capillary plugging, however the mechanism of this protective effect is unclear. We hypothesized that ascorbate-mediated destabilization of the microthrombi through promoting fibrinolysis could contribute to this protection.
We showed that streptokinase, a pro-fibrinolytic agent, reduced the capillary plugging to a similar degree as ascorbate. This similarity provided the impetus for studying the effect of ascorbate ...
Can Ginger Ameliorate Chemotherapy-Induced Nausea? Protocol Of A Randomized Double Blind, Placebo-Controlled Trial, Wolfgang Marx, A Mccarthy, Karin Reid, Luis Vitetta, D Mckavanagh, Damien Thomson, Avni Sali, Elizabeth Isenring
Faculty of Health Sciences & Medicine Publications
Background: Preliminary research shows ginger may be an effective adjuvant treatment for chemotherapy-induced nausea and vomiting but significant limitations need to be addressed before recommendations for clinical practice can be made. Methods/Design: In a double–blinded randomised-controlled trial, chemotherapy-naïve patients will be randomly allocated to receive either 1.2 g of a standardised ginger extract or placebo per day. The study medication will be administrated as an adjuvant treatment to standard anti-emetic therapy and will be divided into four capsules per day, to be consumed approximately every 4 hours (300 mg per capsule administered q.i.d) for five ...
Enacting Kaitiakitanga: Challenges And Complexities In The Governance And Ownership Of Rongoā Research Information, Amohia Boulton, Maui Hudson, Annabel Ahuriri-Driscoll, Albert Stewart
The International Indigenous Policy Journal
This article explores the tensions one research team has faced in securing appropriate governance or stewardship (which we refer to as kaitiakitanga) of research data. Whilst ethical and regulatory frameworks exist which provide a minimum standard for researchers to meet when working with Māori, what our experience has highlighted is there is currently a “governance” gap in terms of who should hold stewardship of research data collected from Māori individuals or collectives. In the case of a project undertaken in the traditional healing space, the organisation best placed to fulfil this governance role receives no funding or support to take ...
The Effects Of Osteopathic Treatment On Common Femoral Artery Blood Flow And Skin Temperature In Spinal Cord Injured And Able-Bodied Individuals, David J.G. Murray
Open Access Dissertations and Theses
Individuals with spinal cord injuries (SCI) are prone to significant alterations in vascular structure and function. This study was designed to examine the effects of osteopathic treatment on mean leg (MLBF) blood flow and skin temperature in the lower extremities of individuals with chronic SCI compared to able-bodied (AB) individuals. Methods: Nine individuals (age 44 ± 17.5 years) with a chronic SCI (C6-T12; AIS A-B; 3.7 ± 4.6 years post-injury) and six AB individuals (38.3 ± 9.7 years) participated. The protocol consisted of 1 interview session and 3 osteopathic treatment sessions. Doppler ultrasound measured the diameter and ...
The Effect Of Blue Light On Pilot And Flight Attendant Behavioral Alertness, 2014 Western Michigan University
The Effect Of Blue Light On Pilot And Flight Attendant Behavioral Alertness, Lori J. Brown, Toine Schoutens, Geoffrey Whitehurst, Troy Booker, Travis Davis, Spencer Losinski, Ryan Diehl
Lori J. Brown
The study aimed to investigate the efficacy of blue light therapy to improve behavioral alertness in flight crew-members. Western Michigan University, College of Aviation, Jeppesen (a Boeing Company), Nature Bright Company, Airline participants, and a leading sleep researcher Schoutens, A.M.C. of FluxPlus, BV, The Netherlands, collaborated to examine whether timed blue light could improve flight crewmember alertness. During the four week study, crewmembers wore actigraph bands to monitor sleep behaviors. Self-assessed levels of sleepiness were recorded using the Karlosinska Sleepiness Scale (KSS), and self-assessed fatigue was measured using the Samn-Perelli (SP) fatigue scale. Participants completed psychomotor vigilance tests ...
Is Hyperbaric Oxygen Therapy An Effective Treatment For Autism? A Review, 2014 University of Tennessee at Chattanooga
Is Hyperbaric Oxygen Therapy An Effective Treatment For Autism? A Review, Daniel Dunleavy, Bruce A. Thyer
Journal of Adolescent and Family Health
Objectives: We review outcome studies regarding the effectiveness of hyperbaric oxygen therapy (HBOT) for Autism Spectrum Disorders (ASD). Method: Studies were identified through electronic bibliographic databases and manual searches of article reference lists. Results: A total of 8 studies met eligibility criteria, consisting of three randomized controlled trials (RCTs), one quasi-experimental study involving a comparison group, two pre-experimental one-group pretest–posttest studies, and two single-system designs. Studies reviewed did not offer credible evidence to suggest that HBOT is an effective treatment for autism. Conclusion: It is premature to call HBOT an effective treatment for Autism and ASD. Individuals clinically treated ...
Traditional Elders In Post-Secondary Stem Education, 2014 Wayne State University
Traditional Elders In Post-Secondary Stem Education, Maria Pontes Ferreira, Betty Mckenna, Fidji Gendron
Nutrition and Food Science Faculty Research Publications
Native/Aboriginal students are underrepresented in Western science, technology, engineering, and mathematics (STEM), due in part to perceived cultural irrelevance. Yet many Native people continue to engage in Indigenous science, such as through traditional medicine and food systems. Recently it was shown that Aboriginal university students are significant users of natural health products (NHP) and learn about NHP from Elders. Thus, in post-secondary educational settings, the presence of Elders may positively impact Native students' interest in science-related topics. At the First Nations University of Canada, partnering of STEM-trained faculty with Elders occurs in community-based research and education endeavours. This paper ...
Animal-Assisted Therapy: Motives And Rewards, 2014 University of New Hampshire
Animal-Assisted Therapy: Motives And Rewards, Kailee Victoria Collins
Animal-assisted therapy is a complimentary therapy utilized in health care to provide goal-directed therapy using dogs. The purpose of this study was to understand what motivates individuals to being animal-assisted volunteering and rewards that encourage and sustain animal-assisted volunteering. This mixed methods study employed quantitative methods, a demographic questionnaire and the Volunteer Motivation Index (VMI), which ranks motives most important to animal-assisted volunteers (N=15) and qualitative methods, a semi-structured interview (N=13). The participants ranked Values most important as a motive on the VMI. Social related variables were ranked low. Content analysis of the interviews yielded five themes: No ...
Music Therapy For Patients Who Have Undergone Hematopoietic Stem Cell Transplant, 2014 University of Nebraska Medical Center
Music Therapy For Patients Who Have Undergone Hematopoietic Stem Cell Transplant, Chelsea G. Ratcliff, Sara Prinsloo, Michael Richardson, Laura Baynham-Fletcher, Richard Lee, Alejandro Chaoul, Marlene Z. Cohen, Marcos De Lima, Lorenzo Cohen
Journal Articles: College of Nursing
Objectives. This study examines the short- and long-term QOL benefits of a music therapy intervention for patients recovering from hematopoietic stem cell transplantation (HSCT). Methods. Ninety allogeneic HSCT patients, after transplant, were randomized to receive ISO-principle (i.e., mood matching) based music therapy (MT; n = 29), unstructured music (UM; n = 30), or usual care (UC; n = 31) for four weeks. The ISO principle posits that patients may shift their mood from one state to another by listening to music that is "equal to" the individual's initial mood state and subsequently listening to music selections that gradually shift in tempo ...
Short-Term Effectiveness Of A Lifestyle Intervention Program For Reducing Selected Chronic Disease Risk Factors In Individuals Living In Rural Appalachia: A Pilot Cohort Study, David Drozek, Hans Diehl, Masato Nakazawa, Tom Kostohryz, Darren Morton, Jay Shubrook
Education Papers and Journal Articles
Most Western chronic diseases are closely tied to lifestyle behaviors, and many are preventable. Despite the well-distributed knowledge of these detrimental behaviors, effective efforts in disease prevention have been lacking. Many of these chronic diseases are related to obesity and type " diabetes, which have doubled in incidence during the last 35 years. The Complete Health Improvement Program (CHIP) is a community-based, comprehensive lifestyle modification approach to health that has shown success in addressing this problem. This pilot study demonstrates the effectiveness of CHIP in an underserved, rural, and vulnerable Appalachian population. Two hundred fourteen participants in CHIP collectively demonstrated significant ...
Cura Personalis: A Healthcare Delivery Quandary At The End Of Life, 2014 The Catholic University of America, Columbus School of Law
Cura Personalis: A Healthcare Delivery Quandary At The End Of Life, George P. Smith Ii
Scholarly Articles and Other Contributions
Holistic Medicine traces its provenance to the foundational value or chrism of the Society of Jesus of cura personalis which directs respect be given to all individuals and to their souls — especially whenever medical healing is required. Today, the notion of best patient care should include not merely attention to somatic issues of refractory pain management but, equally, to non-somatic or existential suffering. It is at the end-stage of life that palliative — as opposed to curative — care must be provided. When a condition is seen as medically futile, this Article advocates palliative or deep sedation — when consistent with patient values ...
Modern Cavemen? Stereotypes And Reality Of The Ancestral Health Movement, 2013 Ancestral Health Society
Modern Cavemen? Stereotypes And Reality Of The Ancestral Health Movement, David B. Schwartz, Hamilton M. Stapell
Journal of Evolution and Health
Both academic and popular interest in the ancestral health movement, or “paleo” lifestyle, has grown rapidly in recent years. More people than ever are joining the movement, and more books and articles are being published on the topic. Media coverage and certain societal preconceptions of the movement have also increased. More often than not, followers of a paleo lifestyle are thought to be “modern cavemen”: athletic, single, meat-eating, young, white, and male. To test whether or not these stereotypes are true, the authors of the present study created the first large, academic survey (N = 3,967) of the ancestral health ...
Medicine And Doctoring In Ancient Mesopotamia, 2013 Grand Valley State University
Medicine And Doctoring In Ancient Mesopotamia, Emily K. Teall
Grand Valley Journal of History
Medicine and pharmaceuticals in Mesopotamia during the span of c. 3000-1000 BCE were more sophisticated than many ancient and modern scholars from other cultures would concede. The limited historical evidence in the form of cuneiform texts and the complementary archaeological material allow for medical practice in this long time span to be examined as a whole. There were two dichotomous traditions of healing present in ancient Mesopotamia, one more therapeutic and one more religious; they were non-competitive and both considered reputable and essential. The therapeutic tradition is given a closer examination in order to provide a picture of how pharmaceutical ...
Best Bodybuilding Supplements : A Beginners Guide, 2013 SelectedWorks
Best Bodybuilding Supplements : A Beginners Guide, Lissa Coffey
If you are a novice and want to build a muscular body then it is important that along with a healthy diet and exercise regime, you have made a right choice for the best sports nutrition supplements ( http://goo.gl/r1OXcb ). These products mainly perform two important functions, first they remove the extra fat from the body and assists in building muscles. O