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Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons

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Functional Analysis Of The Molluscum Contagiosum Virus Mc160 Death Effector Domain-Containing Protein Rxdl Motif, Sarah Weber 2015 Seton Hall University

Functional Analysis Of The Molluscum Contagiosum Virus Mc160 Death Effector Domain-Containing Protein Rxdl Motif, Sarah Weber

Seton Hall University Dissertations and Theses (ETDs)

The Molluscum contagiosum virus (MCV) is a member of the Poxviridae family that causes benign skin lesions. MCV lesions persist on average for 8-12 months in otherwise healthy individuals. MCV lesions are characterized by reduced inflammation. The persistence and reduction of inflammation at the site of MCV lesions have been attributed to MCV immune evasion genes. MCV encodes two death effector domain (DED) containing proteins, MC159 and MC160. DEDs are found in cellular proteins such as FADD and procaspase-8. These cellular proteins are involved in several innate immune responses such as apoptosis and activation of interferon (IFN). Presumably, MC159 and ...


A Study To Evaluate The Maximal Dose Administration At Two Different Locations In Two Different Vdr4 High Frequency Percussive Ventilator (Hpfv) Circuits, Jeff L. Heltborg, Bethany S. Kobza, Ace Nilson 2015 Legacy Health System

A Study To Evaluate The Maximal Dose Administration At Two Different Locations In Two Different Vdr4 High Frequency Percussive Ventilator (Hpfv) Circuits, Jeff L. Heltborg, Bethany S. Kobza, Ace Nilson

Student Research Symposium

The purpose of this study was to determine if the positioning of a nebulizer at two different locations in the VDR4, a specialty ventilator, would result in differing dose administrations of a bronchodilator, Albuterol Sulfate. We hypothesized that placement near the endotracheal tube will provide greater dose deposition. The ventilator was set up to mimic the normal adult patient. Administration was done through the nebulizer placed in the ventilator circuit either before the humidifier or between the endotracheal tube and the VDR 4’s Phasitron. Three trials were performed using a standard dose of Albuterol for each trial. The mass ...


The Characterization Of Amyloid Fibrils And Novel Synthetic Heparin-Binding Peptides Binding To Cell Surfaces, Nicole Marie Hackenbrack 2015 University of Tennessee, Knoxville

The Characterization Of Amyloid Fibrils And Novel Synthetic Heparin-Binding Peptides Binding To Cell Surfaces, Nicole Marie Hackenbrack

University of Tennessee Honors Thesis Projects

No abstract provided.


Fiber Optic Bandage, Logan McNeil 2015 University of Tennessee, Knoxville

Fiber Optic Bandage, Logan Mcneil

University of Tennessee Honors Thesis Projects

No abstract provided.


Oral Wellness: Using Occupational Therapy To Enhance Oral Hygiene Delivery In Long-Term Care, Lauryn J. Banovitz, Liberty Bellah, Rosemarie Lion 2015 Dominican University of California

Oral Wellness: Using Occupational Therapy To Enhance Oral Hygiene Delivery In Long-Term Care, Lauryn J. Banovitz, Liberty Bellah, Rosemarie Lion

Master's Theses and Capstone Projects

Based on current literature, oral health in long-term care (LTC) facilities is frequently of low priority and does not follow evidence-based best practices. Poor oral health reduces the quality of life of older adult residents and patients and can lead to systemic diseases, such as cardiovascular disease, stroke, and pneumonia, the leading cause of death in LTC. Occupational therapists can play an instrumental role as oral care consultants, and educators, and can act as resource guides to raise the standards of oral care in LTC facilities.

This capstone project explored ways in which occupational therapy, a profession traditionally designated for ...


Optimization Of Fluorescent Detection Of Rotavirus Protein Nsp4 And A Cellular Receptor In Two Cell Lines, Katelyn D. Defrates, Rebecca Walker, Ron Havenar, Rebecca D. Parr 2015 Stephen F Austin State University

Optimization Of Fluorescent Detection Of Rotavirus Protein Nsp4 And A Cellular Receptor In Two Cell Lines, Katelyn D. Defrates, Rebecca Walker, Ron Havenar, Rebecca D. Parr

Bright Ideas Conference

Rotavirus (RV) infections are the most common cause of severe diarrhea in infants and young children worldwide. The two licensed vaccines for RV protect children from common strains of RV, but they are less effective against new emerging RV strains. Therefore, new therapeutics to treat RV infections need to be developed. Recently, we have shown stilbenoids, trans-arachidin-1 (t-A1) and trans-arachidin-3 (t-A3), decrease progeny virus particles by one hundred fold. Likewise, western blot assays show a decrease in the amount of the viral protein NSP4 with the addition of the stilbenoids during a RV infection. This indicates an effect on viral ...


Does Every Patient Need Colonoscopy Follow-Up For Diverticulitis?, Rachel Ackerman, Justin Yamin, Anne Foley, Louise Maranda, Benjamin Hyatt 2015 University of Massachusetts Medical School

Does Every Patient Need Colonoscopy Follow-Up For Diverticulitis?, Rachel Ackerman, Justin Yamin, Anne Foley, Louise Maranda, Benjamin Hyatt

Senior Scholars Program

Background: American College of Gastroenterology guidelines recommend colonoscopy as follow-up after an episode of diverticulitis, as there has been some association between diverticulitis and the diagnosis of colon cancer. There is limited data on the yield of this procedure in this setting. Recent studies have suggested that colonoscopy may only be warranted after episodes of complicated diverticulitis involving CT-proven abscess or reactive lymph nodes, which are associated with a higher likelihood of the presence of occult colon cancer.

Objective: The primary objective is to retrospectively examine the results of colonoscopy done for follow-up of diverticulitis at our center, specifically looking ...


Detection Of Igg4-Specific Autoantibodies In Rheumatoid Arthritis Serum Samples, Azra Borogovac, Youmna Lahoud, Janice Weaver, Sheldon M. Cooper, Mercedes Rincon, Jonathan Kay, Ellen M. Gravallese 2015 University of Massachusetts Medical School

Detection Of Igg4-Specific Autoantibodies In Rheumatoid Arthritis Serum Samples, Azra Borogovac, Youmna Lahoud, Janice Weaver, Sheldon M. Cooper, Mercedes Rincon, Jonathan Kay, Ellen M. Gravallese

Senior Scholars Program

Background: Rheumatoid arthritis (RA) is a chronic multi-system autoimmune disease characterized by inflammatory synovitis. Autoantibodies such as rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) have been implicated in the pathogenesis of RA, and are currently important criteria for diagnosis within the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria.1 Yet, many patients diagnosed with RA do not have measurable circulating ACPA or RF which may result in delayed diagnosis and treatment. After IgG1, IgG4 is the second most predominant isotype among ACPA and RF; however it is not detected in currently available diagnostic ...


Location Of All-Cause 30-Day Readmission Following Total Joint Replacement: Surgical Hospital Versus Outside Hospital, Leslie R. Harrold, David C. Ayers, Philip Noble, Regis O'Keefe, Tom Bowen, Matthew Sloan, Patricia D. Franklin 2015 University of Massachusetts Medical School

Location Of All-Cause 30-Day Readmission Following Total Joint Replacement: Surgical Hospital Versus Outside Hospital, Leslie R. Harrold, David C. Ayers, Philip Noble, Regis O'Keefe, Tom Bowen, Matthew Sloan, Patricia D. Franklin

Senior Scholars Program

Background: Evaluating posthospital complications and hospital readmissions in the United States is limited under the current system. This is due to an inability to quantify posthospital care delivered to patients at locations other than the surgical hospital. In order to circumvent this issue, information can be sought directly from patients about posthospital health care utilization. This approach provides a more complete record in comparison with methods that evaluate complications treated only at the surgical hospital.

Methods: Participants undergoing total joint replacement (TJR) between 5/10/11 and 5/17/11 were identified from the Function and Outcomes Research in Comparative ...


Adipose Tissue Therapeutics For Scar Rehabilitation After Thermal Injury, Dylan Perry, Jorge R. Lujan-Hernandez, Ava Chappell, So Yun Min, Raghu Appasani, Raziel Rojas-Rodriguez, Michael S. Chin, Silvia Corvera, Janice F. Lalikos 2015 University of Massachusetts Medical School

Adipose Tissue Therapeutics For Scar Rehabilitation After Thermal Injury, Dylan Perry, Jorge R. Lujan-Hernandez, Ava Chappell, So Yun Min, Raghu Appasani, Raziel Rojas-Rodriguez, Michael S. Chin, Silvia Corvera, Janice F. Lalikos

Senior Scholars Program

Background: Burn injuries are common and in the long term can lead to hypertrophic or keloid scars, pain and pruritus, limited mobility across joints, and disfigurement. Numerous reports suggest adipose derived tissues, including adipose derived stem cells (ADSCs) and processed lipoaspirate, can improve acutely healing wounds from a variety of etiologies including excisional, thermal, and radiation injuries by both secretion of growth factors and direct differentiation. There are many options for scar treatment, including laser therapy, silicone sheets, steroid injection, and even skin grafting however these techniques either lack optimal efficacy or involve significant cost and morbidity. Clinical case series ...


The Deaf Cyborg: Analyzing Technoscience, Gender, And Ability, Callahan Roan 2015 Georgia State University

The Deaf Cyborg: Analyzing Technoscience, Gender, And Ability, Callahan Roan

Georgia State Undergraduate Research Conference

Gsurc 2015


Heightened Levels Of Stress And Contributing Factors In Caregivers Of Special Needs Children, Heather Velon 2015 Georgia State University

Heightened Levels Of Stress And Contributing Factors In Caregivers Of Special Needs Children, Heather Velon

Georgia State Undergraduate Research Conference

No abstract provided.


Methotrexate And Cardiovascular Events, Alpesh Shah 2015 The University of Western Ontario

Methotrexate And Cardiovascular Events, Alpesh Shah

University of Western Ontario - Electronic Thesis and Dissertation Repository

We conducted a systematic review and meta-analysis to assess the association of MTX with cardiovascular morbidity, cardiovascular mortality and all-cause mortality in patients with autoimmune disease. Our primary outcome was incident cardiovascular events. After screening 13,479 citations, we identified a total of 30 eligible studies. We synthesized adjusted risk estimates using a random effects model. MTX was significantly associated with a 25% reduction in cardiovascular events (pooled RR: 0.75, 95% CI: 0.65, 0.86, I2: 11%), a 55% reduction in cardiovascular mortality (0.45, 95% CI: 0.26, 0.80, I2: 33%) and a 40 ...


Mcnamara 2014 Mmb1075 - Low Magnification Confocal Microscopy Of Tumor Angiogenesis, George McNamara 2015 M.D. Anderson Cancer Center

Mcnamara 2014 Mmb1075 - Low Magnification Confocal Microscopy Of Tumor Angiogenesis, George Mcnamara

George McNamara

McNamara 2014 MMB1075 - Low Magnification Confocal Microscopy of Tumor Angiogenesis

Book chapter from Paddock 2014 Confocal Microscopy

Book is online at http://www.springer.com/us/book/9781588293510


Focus On Microscopy Fom 2006-2015 Abstracts, George McNamara 2015 M.D. Anderson Cancer Center

Focus On Microscopy Fom 2006-2015 Abstracts, George Mcnamara

George McNamara

Focus On Microscopy FOM 2006-2015 abstracts

FOM's are cutting edge microscopy meetings. Their abstracts are posted online soon after the meeting. FOM2015's abstracts are at http://www.focusonmicroscopy.org/2015/program.html

I have been downloading the single PDF abstracts, and making a single large PDF. every year. I figure the "annual organized" PDF may be useful to others, so am posting a ZIP file here containing: FOM 2006 FOM 2007 FOM 2008 FOM 2009 FOM 2010 FOM 2011 FOM 2012 FOM 2013 FOM 2014 FOM 2015 I note the abstracts do not contain copyright notices, but anyone ...


Non-Invasive Quantification Of Alveolar Morphometry Measurements In Older Never-Smokers, Gregory A. Paulin 2015 The University of Western Ontario

Non-Invasive Quantification Of Alveolar Morphometry Measurements In Older Never-Smokers, Gregory A. Paulin

University of Western Ontario - Electronic Thesis and Dissertation Repository

Diffusion-weighted noble gas pulmonary magnetic resonance imaging (MRI) provides in vivo images with a contrast uniquely sensitive to molecular displacement at cellular and sub-cellular length scales. We estimated the external airway radius (R) and internal airway radius (r) of the alveolar dimensions to evaluate potential differences in acinar duct morphometries in healthy older never-smokers and compared those with a group of ex-smokers. The acinar duct and alveolar MRI morphometry results were within the physiologically-valid range of parameters. Estimated values of internal (r) and external (R) airway radius as well as alveolar sheath (h) and mean linear intercept (Lm) for ...


Human Issues In Horticulture: A Bibliography, Diana M. Farmer 2015 Kansas State University

Human Issues In Horticulture: A Bibliography, Diana M. Farmer

NPP eBooks

This is a comprehensive bibliography of a rather broad subject area—horticultural therapy. The subject reflects a change in the definition of horticulture as the art and science of growing fruits, vegetables and flowers to include horticulture’s effects on human well-being. The number of citations also reflects the growth and continuing evolvement of this discipline. This bibliography does not include journal articles. It does include monographs, treatises, books, pamphlets, theses, dissertations and media published prior to 2000. The gardening references include a human focus and there are references as well to associated topics such as universal design, accessibility, human ...


Spectropathology For The Next Generation: Quo Vadis?, Hugh J. Byrne, Malgorzata Baranska, Gerwin J. Pupples, Nick Stone, Bayden Wood, Kathleen M. Gough, Peter Lasch, Phil Heraud, Josep Sulé-Suso, Ganesh Sockalingum 2015 Dublin Institute of Technology

Spectropathology For The Next Generation: Quo Vadis?, Hugh J. Byrne, Malgorzata Baranska, Gerwin J. Pupples, Nick Stone, Bayden Wood, Kathleen M. Gough, Peter Lasch, Phil Heraud, Josep Sulé-Suso, Ganesh Sockalingum

Articles

Although the potential of vibrational spectroscopy for biomedical applications has been well demonstrated, translation into clinical practice has been relatively slow. This Editorial assesses the challenges facing the field and the potential way forward. While many technological challenges have been addressed to date, considerable effort is still required to gain acceptance of the techniques among the medical community, standardise protocols, extend to a clinically relevant scale, and ultimately assess the health economics underlying clinical deployment. National and international research networks can contribute much to technology development and standardisation. Ultimately, large-scale funding is required to engage in clinical trials and instrument ...


Piecing The Puzzle Together With The Use Of Physical Therapy, Mikayla Pruitt 2015 Bowling Green State University

Piecing The Puzzle Together With The Use Of Physical Therapy, Mikayla Pruitt

Honors Projects

For my Honors Project I decided to create a set of exercise cards for children with autism. The front of each card had a picture symbolizing the exercise/activity, and on the back included directions, supplies and tips to complete the activity. The following is a selection of a few exercise cards from each of the four exercise sections, as well as the title card, table of contents cards, information cards, and source cards.


Reading Between The Lines: An Intervention Tool For Teaching Theory Of Mind, Megan Jansen 2015 University of Redlands

Reading Between The Lines: An Intervention Tool For Teaching Theory Of Mind, Megan Jansen

Undergraduate Honors Theses

Theory of mind (ToM) is a growing area of interest for speech language pathologists working with children with pragmatic language deficits, especially those with autism spectrum disorders (ASD). Narrative intervention has been a particularly fruitful avenue for encouraging ToM development. This project attempts to compile the best strategies for ToM intervention into a program centered on picture books; to justify the tool according to evidence-based practice guidelines; and to assemble background information, materials and instructions to make it accessible to clinicians. Research about ToM’s characteristics, its role in ASD and its impact on language are reviewed, and strategies for ...


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