The Effect Of Therapeutic Horseback Riding On Balance And Self-Efficacy In Children With Developmental Disabilities, 2016 University of Akron Main Campus
The Effect Of Therapeutic Horseback Riding On Balance And Self-Efficacy In Children With Developmental Disabilities, Lauren M. Hurley, Alexandra Smola
Honors Research Projects
The prevalence of developmental disabilities in children in the United States is a serious problem. Since children with developmental disabilities often show decreased self-efficacy and balance, researchers have studied the effects of interventions in this population. The purpose of this study is to determine the effect of a 10-week THR session on balance and task-specific self-efficacy in children with physical disabilities ages 6 to 18 years old. Bandura’s social cognitive theory and The Physical Stress Theory will guide the quasi-experimental study. A pre-test post-test design will be implemented over a 12 week span at 3 different riding centers in ...
Factors Associated With Colorectal Cancer Screening Among Younger African American Men: A Systematic Review, 2015 University of Minnesota - Twin Cities
Factors Associated With Colorectal Cancer Screening Among Younger African American Men: A Systematic Review, Charles R. Rogers, Patricia Goodson, Margaret Foster
Journal of Health Disparities Research and Practice
Of cancers affecting both men and women, colorectal cancer (CRC) is the second leading cancer killer among African Americans in the U.S. Compared to White men, African American men have incidence and mortality rates 25% and 50% higher from CRC. Despite the benefits of early detection and the availability of effective screening, most adults over age 50 have not undergone testing, and disparities in colorectal cancer screening (CRCS) persist. Owing to CRC’s high incidence and younger age at presentation among African American men, CRCS is warranted at age 45 rather than 50. However, the factors influencing young adult ...
Initial Validation Of A Novel Method Of Presurgical Language Localization Through Functional Connectivity (Fcmri), Stephanie M. Noble, Dustin Scheinost, Susan Y. Bookheimer, Patricia Walshaw, R Todd Constable, Christopher F. Benjamin
Yale Day of Data
OBJECTIVE: Neurosurgery is potentially curative in chronic epilepsy but can only be offered to patients if the surgical risk to language is known. Clinical functional magnetic resonance imaging (fMRI) is an ideal, noninvasive method for localizing language cortex yet remains to be validated for this purpose. We have recently presented a novel method for localizing language cortex. Here we present a preliminary evaluation of this method’s validity. We hypothesized language regions identified using this novel method would demonstrate stronger functional connectivity than randomly generated set of proximal networks. METHOD: fMRI data were collected from five temporal lobe patients (four ...
Effective Treatment Of An Apparent Meniscal Injury Using The Mulligan Concept, 2015 Wilmington College
Effective Treatment Of An Apparent Meniscal Injury Using The Mulligan Concept, Alex J. Rhinehart
Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association
Objective: Present a clinic case demonstrating the effectiveness of the Mulligan Concept (MC) in treating an apparent meniscal injury. The utilization of the MC in the evaluation and treatment of a 20-year-old soccer player with an apparent acute meniscal injury is presented. Background: Meniscal injuries are common knee injuries. The MC is a therapeutic intervention strategy applied as both a treatment-based evaluation and therapeutic intervention. Treatment: The patient was successfully treated in four treatment sessions using the MC. The patient experienced minimal clinically-important differences on a variety of global and regional patient-rated outcomes. Uniqueness: To the author’s knowledge ...
Clinical Outcomes After Drug-Eluting Stents Versus Coronary Artery Bypass Surgery In High Surgical Risk Patients With Left Main Or Three-Vessel Coronary Artery Disease, 2015 Aurora Sinai/Aurora St. Luke's Medical Centers, Aurora Health Care
Clinical Outcomes After Drug-Eluting Stents Versus Coronary Artery Bypass Surgery In High Surgical Risk Patients With Left Main Or Three-Vessel Coronary Artery Disease, Tonga Nfor, Kambiz Shetabi, Wael Hassan, Quinta Nfor, Jayant Khitha, Anjan Gupta, Tanvir Bajwa, Suhail Allaqaband
Journal of Patient-Centered Research and Reviews
Previous studies comparing percutaneous coronary intervention (PCI) with coronary artery bypass graft surgery (CABG) in patients with unprotected left main or three-vessel coronary artery disease (LM-3VD) have excluded patients at high surgical risk. We compared clinical outcomes after PCI with drug-eluting stents to CABG in high surgical risk patients with LM-3VD.
Patients with symptomatic LM-3VD who had Society of Thoracic Surgeons (STS)-predicted operative mortality >5% and were undergoing either PCI with drug-eluting stents or CABG at a tertiary care center from January 2009 to December 2010 were enrolled in this nonrandomized prospective study.
Mean STS score ...
Overview Of The Role Of Duplex Ultrasound For Treatment And Surveillance Of Peripheral Arterial Disease, 2015 Jobst Vascular Institute
Overview Of The Role Of Duplex Ultrasound For Treatment And Surveillance Of Peripheral Arterial Disease, John H. Fish Iii, Peter Klein-Weigel, Gustav Fraedrich
Journal of Patient-Centered Research and Reviews
Imaging strategies for preinterventional planning in symptomatic peripheral artery disease have employed various modalities ranging from duplex ultrasound to noninvasive angiography with computed tomography (CT) or magnetic resonance (MRA). These methods have classically been compared to the gold standard of digital subtraction angiography and are reviewed here in detail through the work of relevant published studies and meta-analyses between 1996 and 2014. In particular, we focus on the diagnostic performance, reproducibility and cost-effectiveness of these aforementioned modalities with respect to mapping the lower extremity arterial tree for planning vascular intervention and surveillance. The data presented suggests comparable sensitivity and specificity ...
Use Of Coronary Techniques In Celiac And Hepatic Artery Stenting In Post-Hepatic Transplant Patients, 2015 Aurora Health Care
Use Of Coronary Techniques In Celiac And Hepatic Artery Stenting In Post-Hepatic Transplant Patients, Harpreet Parmar, Ryan Beard, Mark W. Mewissen, Armaan Shaikh, Tanvir Bajwa
Journal of Patient-Centered Research and Reviews
Hepatic artery stenosis (HAS) remains a rare but serious complication after liver transplantation. While invasive surgical techniques were needed for HAS treatment in the past, recently endovascular techniques, including hepatic artery stenting, have been proven to be a safe and effective treatment. The present work focused on a review of the recent literature regarding HAS as well as recent cases demonstrating the various presentations of HAS and the variety of approaches to endovascular intervention. Our single-center experience has shown endovascular treatment of HAS to be safe and effective, including the two specific cases discussed here. While further research is needed ...
A Non-Invasive Method Of Measuring Respiration While Providing Wireless Power For Rodents With Implantable Devices, Jynx O. Boyne, Daniel J. Pederson, Zhi Wang, Pedro Irazoqui Dr.
The Summer Undergraduate Research Fellowship (SURF) Symposium
Respiratory measurements can be used as diagnostic and research tools. Spirometry is the gold standard for gaining these measurements, but is difficult to use in rodents as it requires an invasive procedure. Total Body Plethysmograpy (TBP) is a non-invasive way to measure respiration rates that does not cause stress to the rodent. In this system, the subject is encased in a solid, constant volume chamber with measurements determining the subject’s respiration. When using TBP in medical or research settings, challenges occur in powering devices within the TBP chamber as wires and other recording equipment compromise the airtightness of the ...
Quantification Of Analyte Concentration From A Paper-Based Lateral Flow Assay Device Using Reflective Sensors, Megan Z. Chiu, Jacqueline Linnes
The Summer Undergraduate Research Fellowship (SURF) Symposium
Paper-based point-of-care (POC) diagnostics is a growing field in global health due to the extreme portability, accuracy, affordability, and ease of use of these tests. Advancements in recent years have led to more accurate detection and improved functionality using multistep molecular diagnostics. Many such assays utilize lateral flow detection strips for visualization of diagnostic results by eye, which limits the results to qualitative Yes/No readouts. This project focused on combining recent developments in paper-based POC diagnostics to develop and optimize an in-house built quantitative paper-based diagnostic reader for lateral flow detection in low-resource settings. Initially different sensors, including photocell ...
Fast Indication Of Bacterial Growth In Clinical Specimens By The Pmeu Approach, 2015 University of Windsor
Fast Indication Of Bacterial Growth In Clinical Specimens By The Pmeu Approach, Elias Hakalehto, Anneli Heitto, Ilkka Pesola, Eva Del Amo, Heikki Paakkanen, Osmo Hänninen, Jouni Pesola
21st International Conference on Environmental Indicators (ICEI 2015)
No abstract provided.
Impact Of Standardized Oral Health Assessment On Preventing Ventilator-Associated Events, 2015 Valparaiso University
Impact Of Standardized Oral Health Assessment On Preventing Ventilator-Associated Events, Juana Ambriz De Williams
Evidence-Based Practice Project Reports
Ventilator-associated pneumonia (VAP) is a common but preventable health-care associated infection that affects up to 20% of mechanically ventilated adult patients, resulting in estimated mortality rates ranging from 13% to 55% (Chahoud, Semaan, Almoosa, 2015; Melsen et al., 2013). In an effort to reduce morbidity, mortality and related costs, the Centers for Disease Control and Prevention (CDC) and the National Healthcare Safety Network (NHSN), proposed ventilator-associated pneumonia prevention as a national patient safety goal. In 2014, amid growing concerns that the subjectivity of existing definitions had led to inconsistent reporting, thereby impeding efforts to reduce VAP, the CDC refocused surveillance ...
Development Of A Comprehensive Massively Parallel Sequencing Panel Of Single Nucleotide Polymorphism And Short Tandem Repeat Markers For Human Identification, 2015 University of North Texas Health Science Center at Fort Worth
Development Of A Comprehensive Massively Parallel Sequencing Panel Of Single Nucleotide Polymorphism And Short Tandem Repeat Markers For Human Identification, David H. Warshauer
Theses and Dissertations
Massively parallel sequencing (MPS) technologies allow for the detection of an unparalleled amount of genetic information with unprecedented speed and relative ease. These qualities make the technology desirable for generating DNA profiles that may be uploaded into forensic offender, arrestee, and family reference database files. This doctoral dissertation research was conducted under the hypothesis that MPS, with its exquisitely high throughput, can provide a system whereby reference samples can be typed for a large battery of markers, providing more discrimination power for forensic DNA typing and offering increased opportunities to develop investigative leads. The design and implementation of large marker ...
Quantifying Measurement Error In Digital Instruments, 2015 Southern Adventist University
Quantifying Measurement Error In Digital Instruments, William B. Laing Iii, Sean Bryant
A first lab experiment clearly illustrates that a glucose meter is actually an excellent source of both random and systematic error, much to the surprise to students and physicians alike. A histogram is constructed and the utility of the standard deviation and standard error to quantify the uncertainty in each measurement and in the mean value, respectively, is demonstrated. From the first lab on, students are challenged to express and interpret confidence intervals in order to form quantitative conclusions. Assessments reveal that many students find this to be surprisingly challenging.
Progression Of Large Lymphoma Is Significantly Impeded With A Combination Of Gemcitabine Chemotherapy And Dendritic Cells Intra-Tumor Vaccination, 2015 Medical School of Southeast University
Progression Of Large Lymphoma Is Significantly Impeded With A Combination Of Gemcitabine Chemotherapy And Dendritic Cells Intra-Tumor Vaccination, Xue-Jun Zhu, Zhongfa Yang, Jin-Yong Zhou, Li Liu, Xue-Mei Sun, Zhen-Fang Fan, Shou-You Hu, Yu-Chao Chen, Wei-Xia Li, Meng Cao, Li-Xin Wang
Open Access Articles
Relapsed, refractory lymphoma remains to be a challenge and lacks efficient treatment. Some tumor cells escape from treatment, become resistant to chemotherapeutic agents, and rapidly regenerate into large tumors. Lymphoma cells induce accumulation of Gr-1+CD11b+ myeloid derived suppressor cells (MDSCs) in lymphatic organs and their vicinity. MDSCs enable tumor cells to escape from immune cells mediated surveillance and attack. Gemcitabine is a chemotherapeutic agent that eliminates both tumor cells and MDSCs, improving the immune environment favorable for subsequent treatment. We evaluated the effects of low dose gemcitabine combined with intra-tumorally delivered dendritic cells (DCs) for the treatment of A20 ...
Wirelessly Connected Sensor Acquisition System For Remote Nursing Applications, 2015 Kennesaw State University
Wirelessly Connected Sensor Acquisition System For Remote Nursing Applications, Yuhua Hu
Dissertations, Theses and Capstone Projects
Taking advantage of the equipment used in the "Remote Nursing" project, nurses can watch patients' status remotely. The equipment, which is installed in the patient's ward or home, can monitor them and their environment. This project demonstrates this using a microcontroller system that interfaces to a video camera and temperature and humidity sensors in the room. Also a servomotor is installed to control the position of the camera. The microcontroller communicates wirelessly with a PC.
This project is focused on hardware rather than software. It is to test the video camera and sensors being used over the microcontroller through ...
Chemical Biology Of Protein Arginine Modifications In Epigenetic Regulation, 2015 The Scripps Research Institute
Chemical Biology Of Protein Arginine Modifications In Epigenetic Regulation, Jakob Fuhrmann, Kathleen W. Clancy, Paul R. Thompson
Thompson Lab Publications
Review article on histone citrullination (arginine deimination), histone arginine methylation, and noncanonical histone arginine modifications.
A Systematic Review Of Studies Comparing Diagnostic Clinical Prediction Rules With Clinical Judgement, Sharon Sanders, Jenny A. Doust, Paul Glasziou
Faculty of Health Sciences & Medicine Publications
Diagnostic clinical prediction rules (CPRs) are developed to improve diagnosis or decrease diagnostic testing. Whether, and in what situations diagnostic CPRs improve upon clinical judgment is unclear.
We searched MEDLINE, Embase and CINAHL, with supplementary citation and reference checking for studies comparing CPRs and clinical judgment against a current objective reference standard. We report 1) the proportion of study participants classified as not having disease who hence may avoid further testing and or treatment and 2) the proportion, among those classified as not having disease, who do (missed diagnoses) by both approaches. 31 studies of 13 medical conditions were included ...
Novel Roles Of Gata4/6 In The Postnatal Heart Identified Through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation By Adeno-Associated Virus Delivery Of Cre Recombinase, 2015 Boston Children's Hospital
Novel Roles Of Gata4/6 In The Postnatal Heart Identified Through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation By Adeno-Associated Virus Delivery Of Cre Recombinase, Terence W. Prendiville, Haidong Guo, Zhiqiang Lin, Pingzhu Zhou, Sean M. Stevens, Aibin He, Nathan Vandusen, Jinghai Chen, Li Zhong, Da-Zhi Wang, Guangping Gao, William T. Pu
Open Access Articles
GATA4 and GATA6 are central cardiac transcriptional regulators. The postnatal, stage-specific function of the cardiac transcription factors GATA4 and GATA6 have not been evaluated. In part, this is because current Cre-loxP approaches to cardiac gene inactivation require time consuming and costly breeding of Cre-expressing and "floxed" mouse lines, often with limited control of the extent or timing of gene inactivation. We investigated the stage-specific functions of GATA4 and GATA6 in the postnatal heart by using adeno-associated virus serotype 9 to control the timing and extent of gene inactivation by Cre. Systemic delivery of recombinant, adeno-associated virus 9 (AAV9) expressing Cre ...
Insole Antenna For On-Body Telemetry, 2015 Dublin Institute of Technology
Insole Antenna For On-Body Telemetry, Domenico Gaetano, Patrick Mcevoy, Max J. Ammann, Matthias John, Colm Brannigan, Louise Keating, Frances Horgan
A 433 MHz antenna is proposed for integration with the insole of footwear for a body area network. The folded dipole design with an asymmetric groundplane radiates from its edges and considers the close proximity of the human foot and ground surfaces. It functions for different ground conductivity conditions and an on-body communication link with an Inverted F Antenna in the upper body area was evaluated on a static and dynamic human subject. The antenna solution was compliant with Specific Absorption Rate requirements, remains matched and links with upper-body nodes regardless of the body posture and node location.
Demonstrations In Ultrasound Imaging And Beam Steering Using Phased Arrays, 2015 Dickinson College
Demonstrations In Ultrasound Imaging And Beam Steering Using Phased Arrays, Katherine Anne Roy
Honors Theses By Year
Ultrasound imaging is one of the most ubiquitous forms of sonography today. It ranks among the cheapest and safest forms of medical imaging techniques available, and it has a wide range of applications in medicine; it is gentle enough to image a developing fetus, yet can also be powerful enough to destroy a kidney stone. We have developed a series of demonstrations that examine several physical properties of ultrasound, specifically as they pertain to imaging. We intend these demonstrations to be used as a learning aid for students who are studying the physics behind medical imaging. These demonstrations utilize single-source ...