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Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons

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Effect Of Exercise Position On Percent Changes In Serratus Anterior Muscle Thickness, Joseph M. Day 2019 University of Dayton

Effect Of Exercise Position On Percent Changes In Serratus Anterior Muscle Thickness, Joseph M. Day

Joseph Day

Objective: A reliable method for measuring SA thickness with ultrasound imaging has been reported, yet the ability to detect differences in levels of contractility has yet to be established. The purpose of this study was to determine if there are differences in the percent change in thickness of the SA during four different exercise positions performed by healthy individuals.

Design: Observational study

Setting: Laboratory

Participants: Twenty-eight healthy participants, mean age 26 (SD 4, 57% female, 100% right handed)

Methods: Volunteers were positioned in a standardized sitting posture and anatomical landmarks were marked for ultrasound probe positioning. Two resting and two ...


Immunosuppressive Treatment And The Risk Of Diabetes In Rheumatoid Arthritis, Siri Lillegraven, Jeffrey D. Greenberg, George W. Reed, Katherine Saunders, Jeffrey R. Curtis, Leslie R. Harrold, Marc C. Hochberg, Dimitrios A. Pappas, Joel M. Kremer, Daniel H. Solomon 2019 Diakonhjemmet Hospital

Immunosuppressive Treatment And The Risk Of Diabetes In Rheumatoid Arthritis, Siri Lillegraven, Jeffrey D. Greenberg, George W. Reed, Katherine Saunders, Jeffrey R. Curtis, Leslie R. Harrold, Marc C. Hochberg, Dimitrios A. Pappas, Joel M. Kremer, Daniel H. Solomon

Leslie R. Harrold

OBJECTIVE: Inflammation and anti-inflammatory treatments might influence the risk of diabetes. The objective of this study was to assess factors associated with incident diabetes in rheumatoid arthritis (RA).

METHODS: The study population consisted of RA patients from a multi-center cohort study, Corrona. To assess risk associated with disease modifying antirheumatic drug (DMARD) exposure, we assessed five mutually exclusive DMARD groups. Additionally, we assessed the risk associated with body mass index (BMI, < 25, 25-30, > 30 kg/m2) and glucocorticoid usage. Incident cases of diabetes were confirmed through adjudication, and Cox regression models were fit to estimate the risk of incident diabetes.

RESULTS: We ...


Characterizing The Recovery Trajectories Of Knee Range Of Motion For One Year After Total Knee Replacement, Saurabh Mehta, Andrew Rigney, Kyle Webb, Jacob Wesney, Paul W. Stratford, Franklin D. Shuler, Ali Oliashirazi 2019 Marshall University

Characterizing The Recovery Trajectories Of Knee Range Of Motion For One Year After Total Knee Replacement, Saurabh Mehta, Andrew Rigney, Kyle Webb, Jacob Wesney, Paul W. Stratford, Franklin D. Shuler, Ali Oliashirazi

Ali Oliashirazi

DESIGN: Retrospective analysis of routinely collected clinical data.

OBJECTIVE: This study modeled the recovery in knee flexion and extension range of motion (ROM) over 1 year after total knee replacement (TKR).

BACKGROUND: Recovery after TKR has been characterized for self-reported pain and functional status. Literature describing target knee ROM at different follow-up periods after TKR is scarce.

METHODS: Data were extracted for patients who had undergone TKR at a tertiary care hospital at 2, 8, 12, 26, and 52 weeks after TKR. A linear mixed-effects growth model was constructed that investigated the following covariates age, sex, pre-TKR range, body mass ...


Successful Extracorporeal Membrane Oxygenation In The Management Of Acute Respiratory Distress Syndrome And Cardiopulmonary Collapse Secondary To Amniotic Fluid Embolism, Sumon Roy, Nishit A. Biniwale, Venkata S. Pendela, Patricia Oates, Katrina Wojciechowski, Scott C. Feitell 2019 Rochester General Hospital

Successful Extracorporeal Membrane Oxygenation In The Management Of Acute Respiratory Distress Syndrome And Cardiopulmonary Collapse Secondary To Amniotic Fluid Embolism, Sumon Roy, Nishit A. Biniwale, Venkata S. Pendela, Patricia Oates, Katrina Wojciechowski, Scott C. Feitell

The VAD Journal

Amniotic fluid embolism (AFE) is one of the most devastating complications of pregnancy that typically manifests as acute cardiopulmonary collapse during delivery or in the postpartum period. The potential role of extracorporeal membrane oxygenation (ECMO) as a management technique in severe cases of AFE remains largely unknown given the limited literature available. In this report, we present the first case, to our knowledge, of successful implementation of ECMO as a life-saving measure in a case of hemorrhagic shock due to postpartum bleeding complicated by severe AFE leading to acute respiratory distress syndrome (ARDS) ultimately requiring tracheostomy. Hemodynamic decompensation is often ...


Nmd-12: A New Machine-Learning Derived Screening Instrument To Detect Mild Cognitive Impairment And Dementia, Pai-Yi Chiu, Haipeng Tang, Cheng-Yu Wei, Chaoyang Zhang, Guang-Uei Hung, Weihua Zhou 2019 Show Chwan Memorial Hospital

Nmd-12: A New Machine-Learning Derived Screening Instrument To Detect Mild Cognitive Impairment And Dementia, Pai-Yi Chiu, Haipeng Tang, Cheng-Yu Wei, Chaoyang Zhang, Guang-Uei Hung, Weihua Zhou

Faculty Publications

Introduction

Using machine learning techniques, we developed a brief questionnaire to aid neurologists and neuropsychologists in the screening of mild cognitive impairment (MCI) and dementia.

Methods

With the reduction of the survey size as a goal of this research, feature selection based on information gain was performed to rank the contribution of the 45 items corresponding to patient responses to the specified questions. The most important items were used to build the optimal screening model based on the accuracy, practicality, and interpretability. The diagnostic accuracy for discriminating normal cognition (NC), MCI, very mild dementia (VMD) and dementia was validated in ...


Telling A Good Story: The Effects Of Memory Retrieval And Context Processing On Eyewitness Suggestibility, Jessica A. LaPaglia, Jason C.K. Chan 2019 Morningside College

Telling A Good Story: The Effects Of Memory Retrieval And Context Processing On Eyewitness Suggestibility, Jessica A. Lapaglia, Jason C.K. Chan

Jason C.K. Chan

Witnesses are likely to describe a crime many times before testifying or encountering misinformation about that crime. Research examining the effect of retrieval on later suggestibility has yielded mixed results. LaPaglia and Chan manipulated whether misinformation was presented in a narrative or misleading questions, and they found that retrieval increased suggestibility when misinformation was presented in a narrative, but reduced suggestibility when the same misinformation was presented in questions. In the current study, we aimed to address why these differences occurred. Specifically, we examined whether contextual detail and narrative coherence during misinformation exposure influenced the relation between retrieval and suggestibility ...


Visual Contributions To Balance Control During Gait, Kyle Brozek 2019 University of Nebraska at Omaha

Visual Contributions To Balance Control During Gait, Kyle Brozek

Student Research and Creative Activity Fair

We propose to isolate the contributions of continuous OF to the orthogonal relationship between balance and gait control during treadmill walking using a series of conditions. Manipulating the direction of OF using a CAREN (Motek Medical, Amsterdam, Netherlands) virtual reality treadmill environment will isolate these visual contributions in human subjects as they walk. We plan to tease out the effect of OF direction on the relationship between gait and balance control by having healthy young adults perform a series of treadmill walking trials while immersed in a VR environment. This will be done by manipulating the direction of walking and ...


Estimating Variations In Metabolic Cost Within The Stride Cycle During Level And Uphill Walking, Arash Mohammadzadeh Gonabadi 2019 University of Nebraska at Omaha

Estimating Variations In Metabolic Cost Within The Stride Cycle During Level And Uphill Walking, Arash Mohammadzadeh Gonabadi

Student Research and Creative Activity Fair

Indirect calorimetry provides the average cost of a stride cycle and prevents from identifying which part of the gait cycle causes increased metabolic cost in patients, however, recent simulation methods allow estimating the time profile of metabolic cost within the stride cycle. In this study, we compare the estimations of the time profile of the metabolic cost of two simulation methods for level and uphill walking. We used kinematic, kinetic and electromyography data from level and uphill walking (one participant) to estimate the time profiles of metabolic cost using the muscle-level metabolic model of Umberger using electromyography and kinematic data ...


Division I Collegiate Male Basketball Player Post-Surgical Cai With Bone Spur Excision: A Case Report, Jacqueline Gutierrez 2019 University of Nebraska at Omaha

Division I Collegiate Male Basketball Player Post-Surgical Cai With Bone Spur Excision: A Case Report, Jacqueline Gutierrez

Student Research and Creative Activity Fair

A Division I basketball player planted his foot and injured his ankle. He had a significant history of repeated lateral ankle sprains and was evaluated as having a grade 2 ankle sprain. He was referred for imaging revealing significant damage to a variety of tissues including a talar osteochondral defect and joint degeneration. He opted for surgical repair, however, post-surgical rehabilitation did not improve the athlete and a secondary procedure was necessary to correct complications. The initial procedure was successful to repair ligamentous stability of the joint. But was not sufficient to fully restore the joint to full function.


No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report, Lauren M. Hall, Julia Reilly, Mathew J. Most, Jennifer Baima 2019 University of Massachusetts Medical School

No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report, Lauren M. Hall, Julia Reilly, Mathew J. Most, Jennifer Baima

Orthopedics and Physical Rehabilitation Publications and Presentations

Background: Cancer rehabilitation is a rapidly growing diverse field in physiatry. This case provides an example where rehabilitation physiatrists played a crucial role in the pain management, education, and rehabilitation before and after a palliative amputation. Due to her limited resources, both in her home country and in her local community, she could not access appropriate care that may have prevented the need for amputation. Though amputation is not generally accepted as the first line of treatment for pain, there have been several reports of palliative amputation in metastatic cancer patients. In particular, fore quarter amputations have been reported in ...


Diabetic Neuropathic Foot Without Neuropathy: Could It Be Cancer? - A Case Report, Jennifer Baima, Felix Santiago, Mathew J. Most 2019 University of Massachusetts Medical School

Diabetic Neuropathic Foot Without Neuropathy: Could It Be Cancer? - A Case Report, Jennifer Baima, Felix Santiago, Mathew J. Most

Orthopedics and Physical Rehabilitation Publications and Presentations

We present a case of a 64 year-old diabetic male who presented with months of progressively worsening foot pain and swelling, who was initially diagnosed with Charcot joint disease.(CJD) He was ultimately found to have a very rare tumor.


Telling A Good Story: The Effects Of Memory Retrieval And Context Processing On Eyewitness Suggestibility, Jessica A. LaPaglia, Jason C.K. Chan 2019 Morningside College

Telling A Good Story: The Effects Of Memory Retrieval And Context Processing On Eyewitness Suggestibility, Jessica A. Lapaglia, Jason C.K. Chan

Psychology Publications

Witnesses are likely to describe a crime many times before testifying or encountering misinformation about that crime. Research examining the effect of retrieval on later suggestibility has yielded mixed results. LaPaglia and Chan manipulated whether misinformation was presented in a narrative or misleading questions, and they found that retrieval increased suggestibility when misinformation was presented in a narrative, but reduced suggestibility when the same misinformation was presented in questions. In the current study, we aimed to address why these differences occurred. Specifically, we examined whether contextual detail and narrative coherence during misinformation exposure influenced the relation between retrieval and suggestibility ...


The “Benefits,” Risks, And Costs Of Routine Infant Circumcision, Stephanie Welch 2019 N/A

The “Benefits,” Risks, And Costs Of Routine Infant Circumcision, Stephanie Welch

Journal of Evolution and Health

No abstract provided.


Jual Obat Aborsi Di Dumai 081325757672 Penjual Obat Cytotec Asli Dumai, baris surya02 2019 University of California, San Francisco

Jual Obat Aborsi Di Dumai 081325757672 Penjual Obat Cytotec Asli Dumai, Baris Surya02

Jual Obat Aborsi Tuntas - Obat Penggugur Kandungan

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Improving The Genetic Diagnosis Of Familial Hypercholesterolemia, Michael Iacocca 2019 The University of Western Ontario

Improving The Genetic Diagnosis Of Familial Hypercholesterolemia, Michael Iacocca

Electronic Thesis and Dissertation Repository

Familial hypercholesterolemia (FH) is a genetic disorder of severely elevated low-density lipoprotein (LDL) cholesterol that is widely underdiagnosed and undertreated. To improve the identification of FH and initiate timely and appropriate treatment strategies, genetic testing is becoming increasingly offered worldwide as a central part of diagnosis. I describe three main ways providing a genetic diagnosis in FH can be improved. First, next-generation sequencing (NGS)-based approaches can be used to reliably identify large-scale variant types known as copy number variations (CNVs) in the LDL receptor gene (LDLR); second, NGS methodology can be further applied to extend CNV screening to additional ...


Ibuprofen Is A Safe And Effective Alternative To Opioid Analgesics In Dermatologic Surgery, Brittny Call Ahrendes 2019 Lynchburg University, VA

Ibuprofen Is A Safe And Effective Alternative To Opioid Analgesics In Dermatologic Surgery, Brittny Call Ahrendes

Lynchburg Journal of Medical Science

Patients undergo dermatologic surgery for a variety of reasons. Cases may be minor excisions with simple repair or extensive Mohs micrographic surgery (MMS) requiring involved flap reconstruction. Many patients develop some level of postoperative pain (POP) requiring oral analgesia and traditional methods of pain control include oral acetaminophen (Ac), or an opioid such as Ac + codeine. Opioids are associated with unpleasant adverse events such as nausea, pruritus, constipation, altered mental status, and potential for addiction, thus requiring judicious use. Alternatively, ibuprofen (Ibu), a non-steroidal anti-inflammatory (NSAID), has a proven efficacy and tolerability profile, but its use is often discouraged by ...


Npo Or Ama? Patients Allowed Clear Liquids Up To 2 Hours Pre-Procedure Have Equivalent Aspiration Risk And Increased Patient Satisfaction, Erich Smith 2019 University of Wayne State Medical School

Npo Or Ama? Patients Allowed Clear Liquids Up To 2 Hours Pre-Procedure Have Equivalent Aspiration Risk And Increased Patient Satisfaction, Erich Smith

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Itou K, Fukuyama T, Sasabuchi Y, et al. Safety and efficacy of oral rehydration therapy until 2 h before surgery: a multicenter randomized controlled trial. Journal of Anesthesia. 2012;26(1):20-27. doi: 10.1007/s00540-011-1261-x.


Memantine Unproven To Provide Any Clinical Benefit In Cases Of Vascular Cognitive Impairment, Irene Kitromelides 2019 Wayne State University School of Medicine

Memantine Unproven To Provide Any Clinical Benefit In Cases Of Vascular Cognitive Impairment, Irene Kitromelides

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Wilcock G, Möbius HJ, Stöffler A. A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500). Int Clin Psychopharmacol. 2002 Nov;17(6):297-305. doi: 10.1097/00004850-200211000-00005.


Locus‐Specific Concordance Of Genomic Alterations Between Tissue And Plasma Circulating Tumor Dna In Metastatic Melanoma, Leslie Calapre, Tindaro Giardina, Cleo Robinson, Anna L. Reid, Zeyad Al-Ogaili, Michelle R. Pereira, Ashleigh C. McEvoy, Lydia Warburton, Nicholas K. Hayward, Muhammad A. Khattak, Tarek M. Meniawy, Michael Millward, Benhur Amanuel, Melanie R. Ziman, Elin S. Gray 2019 Edith Cowan University

Locus‐Specific Concordance Of Genomic Alterations Between Tissue And Plasma Circulating Tumor Dna In Metastatic Melanoma, Leslie Calapre, Tindaro Giardina, Cleo Robinson, Anna L. Reid, Zeyad Al-Ogaili, Michelle R. Pereira, Ashleigh C. Mcevoy, Lydia Warburton, Nicholas K. Hayward, Muhammad A. Khattak, Tarek M. Meniawy, Michael Millward, Benhur Amanuel, Melanie R. Ziman, Elin S. Gray

ECU Publications Post 2013

Circulating tumor DNA (ctDNA) may serve as a surrogate to tissue biopsy for noninvasive identification of mutations across multiple genetic loci and for disease monitoring in melanoma. In this study, we compared the mutation profiles of tumor biopsies and plasma ctDNA from metastatic melanoma patients using custom sequencing panels targeting 30 melanoma-associated genes. Somatic mutations were identified in 20 of 24 melanoma biopsies, and 16 of 20 (70%) matched-patient plasmas had detectable ctDNA. In a subgroup of seven patients for whom matching tumor tissue and plasma were sequenced, 80% of the mutations found in tumor tissue were also detected in ...


Citalopram In First Episode Schizophrenia: The Decifer Trial, Donald C. Goff, Xiaoduo Fan 2019 NYU Langone Health

Citalopram In First Episode Schizophrenia: The Decifer Trial, Donald C. Goff, Xiaoduo Fan

Open Access Articles

Antidepressants are frequently prescribed in first episode schizophrenia (FES) patients for negative symptoms or for subsyndromal depressive symptoms, but therapeutic benefit has not been established, despite evidence of efficacy in later-stage schizophrenia. We conducted a 52 week, placebo-controlled add-on trial of citalopram in patients with FES who did not meet criteria for major depression to determine whether maintenance therapy with citalopram would improve outcomes by preventing or improving negative and depressive symptoms. Primary outcomes were negative symptoms measured by the Scale for Assessment of Negative Symptoms and depressive symptoms measured by the Calgary Depression Scale for Schizophrenia; both were analyzed ...


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