Veterinary Medicine Commons^™

Dr. Snook And The Coed: The Theora Hix Affair And Murder, James R. Hennessy M.D.

Annual Conference Presentations, Papers, and Posters

Dr. James Howard Snook was born in South Lebanon, Ohio in Warren County in 1879. He was both an alumnus and later a faculty member of the Ohio State University College of Veterinary Medicine. In 1922 Dr. Snook married Helen Marple and had a daughter. In 1926 Dr. Snook began an affair with an OSU medical student, Theora Hix. The affair lasted about 2 years. During a visit in 1929 Theora Hix allegedly threatened to harm Dr. Snook's wife and child. Dr. Snook murdered her and was sentenced to death in February of 1930.

Assessment Of Introduction Pathway For Novel Avian Influenza Virus Into North America By Wild Birds From Eurasia, Ryan S. Miller, Steven J. Sweeney, Judy E. Akkina, Emi K. Saito

Other Publications in Zoonotics and Wildlife Disease

A critical question surrounding emergence of novel strains of avian influenza viruses (AIV) is the ability for wild migratory birds to translocate a complete (unreassorted whole genome) AIV intercontinentally. Virus translocation via migratory birds is suspected in outbreaks of highly pathogenic strain A(H5N1) in Asia, Africa, and Europe. As a result, the potential intercontinental translocation of newly emerging AIV (e.g. A(H7N9) from Eurasia to North America via migratory movements of birds) remains a concern. An estimated 1.48 to 2.91 million aquatic birds, principally Anseriformes (ducks, geese, and swans) and Charadriiformes (gulls, terns, and shorebirds) move ...

Optimizing The Purification Of Wild Type And Mutant Recombinant Phospholipase D: Approaches To Developing A C. Pseudotuberculosis Vaccine, Utsav M. Patwardhan

Biochemistry Student Honors Theses

No abstract provided.

Gentle Doctor (Vol. 26, No. 1), Iowa State University College Of Veterinary Medicine

Gentle Doctor

Contents: Last But Not Least; Let's Give Them Something to Talk About; Beyond the Classroom: Hands-on experience and so much more; ISU Veterinarian Leads Extension Expertise in Afghanistan & Pakistan

Comparison Of Multilocus Sequence Analysis And Virulence Genotyping Of Escherichia Coli From Live Birds, Retail Poultry Meat, And Human Extraintestinal Infection, Jessica L. Danzeisen, Yvonne Wannemuehler, Lisa K. Nolan, Timothy J. Johnson

Veterinary Microbiology and Preventive Medicine Publications and Papers

To examine the correlations between virulence genotyping and multilocus sequence analysis of Escherichia coli from poultry and humans, 88 isolates were examined. The isolates were selected from a population of over 1000 based on their assignment to nine different virulence genotyping clusters. Clustering based on multilocus sequence analysis mostly correlated with virulence genotyping, although multilocus sequence analysis demonstrated higher discriminatory ability and greater reliability related to inferred phylogenetic relationships. No distinct patterns in host source were observed using inferred phylogeny through multilocus sequence analysis, indicating that human, avian, and retail meat isolates are diverse, and some belong to multiple shared ...

Strong Concordance Between Transcriptomic Patterns Of Spleen And Peripheral Blood Leukocytes In Response To Avian Pathogenic Escherichia Coli Infection, Erin E. Sandford, Megan Orr, Xianyao Li, Huaijun Zhou, Timothy J. Johnson, Subhashinie Kariyawasam, Peng Liu, Lisa K. Nolan, Susan J. Lamont

Veterinary Microbiology and Preventive Medicine Publications and Papers

Avian pathogenic Escherichia coli (APEC) causes morbidity in chickens and exhibits zoonotic potential. Understanding host transcriptional responses to infection aids the understanding of protective mechanisms and serves to inform future colibacillosis control strategies. Transcriptomes of spleen and peripheral blood leukocytes (PBLs) of the same individual birds in response to APEC infection were compared to identify common response patterns and connecting pathways. More than 100 genes in three contrasts examining pathology and infection status were significantly differentially expressed in both tissues and similarly regulated. Tissue-specific differences in catalytic activity, however, appear between birds with mild and severe pathology responses. Early expression ...

Genotypic And Phenotypic Traits That Distinguish Neonatal Meningitis-Associated Escherichia Coli From Fecal E. Coli Isolates Of Healthy Human Hosts, Catherine M. Logue, Curt Doetkott, Paul M. Mangiamele, Yvonne Wannemuehler, Timothy J. Johnson, Kelly A. Tivendale, Ganwu Li, Julie S. Sherwood, Lisa K. Nolan

Veterinary Microbiology and Preventive Medicine Publications and Papers

Neonatal meningitis Escherichia coli (NMEC) is one of the top causes of neonatal meningitis worldwide. Here, 85 NMEC and 204 fecal E. coli isolates from healthy humans (HFEC) were compared for possession of traits related to virulence, antimicrobial resistance, and plasmid content. This comparison was done to identify traits that typify NMEC and distinguish it from commensal strains to refine the definition of the NMEC subpathotype, identify traits that might contribute to NMEC pathogenesis, and facilitate choices of NMEC strains for future study. A large number of E. coli strains from both groups were untypeable, with the most common serogroups ...

Escherichia Coli Isolates That Carry Vat, Fyua, Chua, And Yfcv Efficiently Colonize The Urinary Tract, Rachel R. Spurbeck, Paul C. Dinh Jr., Seth T. Walk, Ann E. Stapleton, Thomas M. Hooton, Lisa K. Nolan, Kwang Sik Kim, James R. Johnson, Harry L. T. Mobley

Veterinary Microbiology and Preventive Medicine Publications and Papers

Extraintestinal Escherichia coli (ExPEC), a heterogeneous group of pathogens, encompasses avian, neonatal meningitis, and uropathogenic E. coli strains. While several virulence factors are associated with ExPEC, there is no core set of virulence factors that can be used to definitively differentiate these pathotypes. Here we describe a multiplex of four virulence factor-encoding genes, yfcV, vat,fyuA, and chuA, highly associated with uropathogenic E. coli strains that can distinguish three groups of E. coli: diarrheagenic and animal-associated E. colistrains, human commensal and avian pathogenic E. coli strains, and uropathogenic and neonatal meningitis E. coli strains. Furthermore, human intestinal isolates that encode ...

Complete Genome Sequence Of The Avian Pathogenic Escherichia Coli Strain Apec O78, Paul M. Mangiamele, Bryon A. Nicholson, Yvonne Wannemuehler, Torsten Seemann, Catherine M. Logue, Ganwu Li, Kelly A. Tivendale, Lisa K. Nolan

Veterinary Microbiology and Preventive Medicine Publications and Papers

Colibacillosis, caused by avian pathogenic Escherichia coli (APEC), is a significant disease, causing extensive animal and financial losses globally. Because of the significance of this disease, more knowledge is needed regarding APEC's mechanisms of virulence. Here, we present the fully closed genome sequence of a typical avian pathogenic E. coli strain belonging to the serogroup O78.

Deep Sequencing-Based Transcriptome Analysis Of Chicken Spleen In Response To Avian Pathogenic Escherichia Coli (Apec) Infection, Qinghua Nie, Xiquan Zhang, Erin E. Sandford, Susan J. Lamont, Lisa K. Nolan

Veterinary Microbiology and Preventive Medicine Publications and Papers

Avian pathogenic Escherichia coli (APEC) leads to economic losses in poultry production and is also a threat to human health. The goal of this study was to characterize the chicken spleen transcriptome and to identify candidate genes for response and resistance to APEC infection using Solexa sequencing. We obtained 14422935, 14104324, and 14954692 Solexa read pairs for non-challenged (NC), challenged-mild pathology (MD), and challenged-severe pathology (SV), respectively. A total of 148197 contigs and 98461 unigenes were assembled, of which 134949 contigs and 91890 unigenes match the chicken genome. In total, 12272 annotated unigenes take part in biological processes (11664), cellular ...

Genome Analysis And Phylogenetic Relatedness Of Gallibacterium Anatis Strains From Poultry, Timothy J. Johnson, Jessica L. Danzeisen, Darrell W. Trampel, Lisa K. Nolan, Torsten Seemann, Ragnhild J. Bager, Anders M. Bojesen

Veterinary Microbiology and Preventive Medicine Publications and Papers

Peritonitis is the major disease problem of laying hens in commercial table egg and parent stock operations. Despite its importance, the etiology and pathogenesis of this disease have not been completely clarified. Although avian pathogenic Escherichia coli (APEC) isolates have been incriminated as the causative agent of laying hen peritonitis, Gallibacterium anatis are frequently isolated from peritonitis lesions. Despite recent studies suggesting a role for G. anatis in the pathogenesis of peritonitis, little is known about the organism’s virulence mechanisms, genomic composition and population dynamics. Here, we compared the genome sequences of three G. anatis isolates in an effort ...

Porcine E. Coli: Virulence-Associated Genes, Resistance Genes And Adhesion And Probiotic Activity Tested By A New Screening Method, Peter Schierack, Stefan Rödiger, Christoph Kuhl, Rico Hiemann, Dirk Roggenbuck, Ganwu Li, Jörg Weinreich, Enrico Berger, Lisa K. Nolan, Bryon A. Nicholson, Antje Römer, Ulrike Frömmel, Lothar H. Wieler, Christian Schröder

Veterinary Microbiology and Preventive Medicine Publications and Papers

We established an automated screening method to characterize adhesion of Escherichia colito intestinal porcine epithelial cells (IPEC-J2) and their probiotic activity against infection by enteropathogenic E. coli (EPEC). 104 intestinal E. coli isolates from domestic pigs were tested by PCR for the occurrence of virulence-associated genes, genes coding for resistances to antimicrobial agents and metals, and for phylogenetic origin by PCR. Adhesion rates and probiotic activity were examined for correlation with the presence of these genes. Finally, data were compared with those from 93 E. coli isolates from wild boars.

Isolates from domestic pigs carried a broad variety of ...

Equine Protozoal Myeloencephalitis: Investigation Of Genetic Susceptibility And Assessment Of An Equine Infection Method, Breanna M. Gaubatz

Theses and Dissertations--Veterinary Science

Equine protozoal myeloencephalitis (EPM) is a progressive neurological disease of horses caused by Sarcocystis neurona. Two projects were conducted to identify factors involved in the development of EPM. The first study explored a possible genetic susceptibility to EPM by attempting a genome-wide association study (GWAS) on formalin-fixed, paraffin-embedded (FFPE) tissue from 24 definitively-positive EPM horses. DNA extracted from tissues older than 14 months was inadequate for SNP analysis on the Illumina Equine SNP50 BeadChip probably due to degradation and formalin cross-linking. Results were inconclusive as analysis was not possible with the small sample set. The second study evaluated an artificial ...

Validation Of A Lameness Model In Sows Using Physiological And Mechanical Measurements, Locke A. Karriker, Caitlyn E. Abell, Monique D. Pairis-Garcia, Whitney A. Holt, Gang Sun, Johann F. Coetzee, Anna K. Johnson, Steven J. Hoff, Kenneth J. Stalder

Agricultural and Biosystems Engineering Publications and Papers

The objective of this study was to develop a validated, transient, chemically induced lameness model in sows using subjective and objective lameness detection tools. Experiment 1 determined an effective joint injection technique based on volume and placement of dye using feet collected from 9 finisher pigs and 10 multiparity cull sow carcasses. Experiment 2 confirmed the injection technique in live animals and produced a transient clinical lameness in 4 anesthetized sows injected with amphotericin B (15 mg/mL) in the distal interphalangeal joints of the claw. Clinical lameness was assessed by a categorical lameness scoring system, and a postmortem visual ...

Inter-Institutional Sharing Of Veterinary Specialty Boards Reading Lists Using Libguides™ (Poster), Jessica Page, Heather Moberly, Vicki Croft, Ann R. Viera, Laura Rey

Ann R Viera MSLIS

No abstract provided.

Maternal Obesity Alters Fetal Development Due To Impaired Placental Function And Has Lasting Effects On Adult Offspring, Kristin Ann Norwood

Theses and Dissertations in Animal Science

Obesity is an epidemic in many developed nations and maternal obesity can result in developmental alterations in offspring that have long-lasting effects. Two experiments were conducted to determine the impact of maternal obesity on placental development and early embryonic growth and muscle development. Experiment one utilized obese Lethal Yellow (LY) and normal weight C57BL/6 (B6) dams to assess how maternal obesity alters skeletal muscle development in mid-gestational embryos. Embryos from LY dams exhibited decreased embryo and placental weights as well as an increase in the myogenic marker desmin. Furthermore, the adipogenic marker PPARG expression was predominately localized to the ...

The Link, One Health, And Social Capital: A New Strategy For Empathy Education And Social Work, Phil Arkow

International Veterinary Social Work Summit

For 150 years, animal welfare and veterinary advocates have promoted a doctrine that animal welfare will be enhanced by teaching children kindness to animals and responsible animal husbandry practices. However, these efforts have been stymied by societal and professional perceptions that “animal” causes are less worthy than “human” services. Ten significant challenges have made it difficult, if not impossible, to gain access to educators’ curricula and social work training. In a society that continues to place humans’ interests above animals’, it is time to try a new approach that focuses on the human benefits of animal welfare. In particular, a ...

Natural Dog Training Provides New Ways To Understand And Manage Stresses Of Canine Assistance Work, Jean Marie Thompson, Kevin Behan

International Veterinary Social Work Summit

Limiting dis-stress experienced by assisted therapy, crisis response, and combat comfort dogs is a concern of handlers, organizations, and researchers. Dogs communicate feelings via body language especially muzzle expressions and physical behaviors that people and other animals recognize. Projection of dis-stress by dogs negatively impacts therapeutic interactions, distracting and detracting from beneficial flow of feelings. Dog welfare is risked. Behan's Natural Dog Training ("NDT") presents an alternative paradigm for understanding dog dis-stress. NDT is an energy flow model that is different from but compatible with positive reinforcement techniques and attuned to Adrian Bejan's constructal law of nature, a ...

Canines And Childhood Cancer: The Effects Of Animal-Assisted Therapy For Patients, Families And Therapy Dogs, Molly Jenkins Msw, Amy Mccullough Ma, Ashleigh Ruehrdanz Ba, Kevin Morris Ph.D.

International Veterinary Social Work Summit

PLEASE USE THE PDF (available from the "download" link) TO FOLLOW ALONG WITH THE VIDEO

For many people, animals take center stage in their daily lives, offering companionship, comfort, joy and for some, even kinship. Increasingly, greater attention has been given to the roles that animals can play in supporting the health and emotional well-being of people in need, specifically through the use of animal-assisted therapy (AAT). However, while the field of human-animal interaction (HAI) research has expanded enormously in recent years, it is still unclear whether the incorporation of animals into clinical settings is effective from a scientific standpoint ...

Cruelty Intervention Advocacy, A New Approach To Animal Hoarding Interventions, Allison Cardona

International Veterinary Social Work Summit

Animal hoarding affects thousands of animals and people across the United States. Conservative estimates place the number of new cases at two to three thousand per year, though no centralized database exists, so the full scope of the problem is unknown. Unlike intentional, single acts of cruelty, animal hoarding impacts a large number of animals over a prolonged period of time. Any type of animal can be hoarded, though the majority of hoarding situations involve cats and dogs, with numbers ranging from a few dozen to several hundred and even thousands of animals living in a single location. Accumulation of ...