Open Access. Powered by Scholars. Published by Universities.®

Veterinary Medicine Commons

Open Access. Powered by Scholars. Published by Universities.®

10360 Full-Text Articles 14623 Authors 660836 Downloads 57 Institutions

All Articles in Veterinary Medicine

Faceted Search

10360 full-text articles. Page 1 of 150.

Leaders Of The Pack: Women And The Future Of Veterinary Medicine, Julie Kumble, Donald F. Smith 2017 Purdue University

Leaders Of The Pack: Women And The Future Of Veterinary Medicine, Julie Kumble, Donald F. Smith

Purdue University Press Book Previews

Veterinary medicine has undergone sweeping changes in the last few decades. Women now account for 55 percent of the active veterinarians in the field, and nearly 80 percent of veterinary students are women. However, average salaries have dropped as this shift has occurred, and even with women in the vast majority, only 25 percent of leadership roles are held by women.

These trends point to gender-based inequality that veterinary medicine, a profession that tilts so heavily toward women, is struggling to address. How will the profession respond? What will this mean for our students and schools? What will it mean ...


The Indirect Effect Of Bvdv On Immune Suppression: The Role Of Infected Macrophages In Lymphocyte Apoptosis, Karim Abdelsalam 2017 South Dakota State University

The Indirect Effect Of Bvdv On Immune Suppression: The Role Of Infected Macrophages In Lymphocyte Apoptosis, Karim Abdelsalam

Theses and Dissertations

BVDV is an important pathogen of cattle that affects both the dairy and beef industry causing severe economic losses. The main problem of BVDV is the immune suppression that is associated with lymphoid depletion shortly post infection. The mechanism of this immune suppression is not well understood. In this in vitro study, we sought to determine the indirect effect of BVDV infection in macrophages as a key player in the pathogenesis of BVD especially, the apoptotic effect induced on lymphocytes. We infected bovine monocyte-derived macrophages (MDM) with either high or low virulent strains of cytopathogenic or non-cytopathogenic strains of BVDV ...


Economic Impact Of A Ban On The Use Of Over-The-Counter Antibiotics, Dermot J. Hayes, Helen H. Jensen, Lennart Backstrom, Jay Fabiosa 2016 Iowa State University

Economic Impact Of A Ban On The Use Of Over-The-Counter Antibiotics, Dermot J. Hayes, Helen H. Jensen, Lennart Backstrom, Jay Fabiosa

Dermot J. Hayes

Because antibiotic drugs are widely used in starter, grower, finishing, and sow feeds, a ban on their use would impact pork production processes and practices, and therefore would have an economic impact on the U.S. pork industry and pork market. This study considers the economic effects of a ban in pork production, with no change of regulation on other meats. The authors examine the evidence from a range of cases from Sweden to describe what is most likely to occur if a ban on antibiotic drugs in pork production were to be implemented in the United States.


Assessing Readiness For Clinical Practice: Students’ Perspectives Of Their Veterinary Curriculum, L. Chris Sanchez, Alison Kwiatkowski, Jeff Abbott, Dana N. Zimmel, Linda S. Behar-Horenstein 2016 University of Florida College of Veterinary Medicine

Assessing Readiness For Clinical Practice: Students’ Perspectives Of Their Veterinary Curriculum, L. Chris Sanchez, Alison Kwiatkowski, Jeff Abbott, Dana N. Zimmel, Linda S. Behar-Horenstein

The Qualitative Report

Studies describing the effectiveness of a veterinary curriculum from the student perspective are currently sparse. The overall purpose of this investigation was to describe students’ perceived preparedness for clinical practice. Three focus group meetings with fourth year veterinary students were conducted. Data were open-coded and categorized to identify themes. Four main themes emerged: Challenging communications, Un/appreciating curricular experiences, Documenting demands impede case involvement, and Hungering for timely, effective feedback. Overall students felt comfortable talking to clients about medicine but less comfortable discussing euthanasia or money; they appreciated the split clinical curriculum but questioned the value of the 1st/2nd ...


Animal Health Matters, Jane Hennings, Larry Holler, Russ Daly, Linda Fawcett 2016 South Dakota State University

Animal Health Matters, Jane Hennings, Larry Holler, Russ Daly, Linda Fawcett

Animal Health MATTERS Newsletter

[Page] 1 SDSU and SHIC Study on Senecavirus Offers Keen Insights
[Page] 2 Director's Message: Innovation in the Laboratory and Being Proactive in the Protection of Animal Health
[Page] 2 Bovine Abortion-Sample Submission Guidelines
[Page] 3 South Dakota One Health Meeting Covers Bacterial Zoonotic Disease
[Page] 3 Small Ruminant, Poultry Serology Offerings Expanded at the ADRDL
[Page] 4 Molecular Diagnostics Section Evolves, Adds New Tests
[Page] 5 Recent PCR tests Added by ADRDL
[Page] 6 New Employees
[Page] 7 ADRDL Continues Their Critical Role Supporting Animal Exports


Follicular Dynamics In Insulin Resistant Mares, Julio Cesar Prado 2016 University of Tennessee, Knoxville

Follicular Dynamics In Insulin Resistant Mares, Julio Cesar Prado

Masters Theses

Obesity and insulin resistance have been linked to prolonged interovulatory period, aberrations in the estrous cycle, and continuous reproductive activity during the non-breeding season. EMS has been determined to influence the intrafollicular environment of mare ovaries. In humans, insulin resistance has been linked to polycystic ovaries as part of Polycystic Ovarian Syndrome (PCOS). A study was conducted to determine 1) the impact of insulin resistance on follicle growth and size at ovulation, and 2) whether predicted ovulatory follicles respond to hCG administration in Insulin-resistant (IR) mares. Mares were selected for the study based on insulin sensitivity and separated into an ...


Generating An Equation To Predict Post- Farrow Maternal Weight In Multiple Parity Sows, L. L. Thomas, S. S. Dritz, R. D. Goodband, M. D. Tokach, J. M. DeRouchey, J. C. Woodworth 2016 Kansas State University, Manhattan

Generating An Equation To Predict Post- Farrow Maternal Weight In Multiple Parity Sows, L. L. Thomas, S. S. Dritz, R. D. Goodband, M. D. Tokach, J. M. Derouchey, J. C. Woodworth

Kansas Agricultural Experiment Station Research Reports

ost-farrow maternal weight is required when partitioning maternal and fetal weight gains throughout gestation. Equations were developed from the analysis of 150 females (Line 1050, PIC, Hendersonville, TN) to predict the weight of conceptus by difference of pre- and post-farrowing weight change in multi-parity sows. Females were individually weighed as they were moved into the farrowing house at d 110 to 112 of gestation and again at 12 to 24 h after farrowing. Data were divided into 4 groups: (1) parity 1 sows; (2) parity 2 sows; (3) parity 3 sows; and (4) parity 4+ sows. Each group tested 3 ...


Evaluation Of The Effects Of Flushing Feed Manufacturing Equipment With Chemically- Treated Rice Hulls On Porcine Epidemic Diarrhea Virus Cross Contamination During Feed Manufacturing, J. T. Gebhardt, J. C. Woodworth, C. K. Jones, Phillip Charles Gauger, M. D. Tokach, J. M. DeRouchey, R. D. Goodband, M. Muckey, R. A. Cochrane, M. Niederwerder, C. R. Stark, J. Bai, Qi Chen, Jianqiang Zhang, Alejandro Ramirez, Rachel J. Derscheid, Rodger G. Main, S. S. Dritz 2016 Kansas State University, Manhattan

Evaluation Of The Effects Of Flushing Feed Manufacturing Equipment With Chemically- Treated Rice Hulls On Porcine Epidemic Diarrhea Virus Cross Contamination During Feed Manufacturing, J. T. Gebhardt, J. C. Woodworth, C. K. Jones, Phillip Charles Gauger, M. D. Tokach, J. M. Derouchey, R. D. Goodband, M. Muckey, R. A. Cochrane, M. Niederwerder, C. R. Stark, J. Bai, Qi Chen, Jianqiang Zhang, Alejandro Ramirez, Rachel J. Derscheid, Rodger G. Main, S. S. Dritz

Kansas Agricultural Experiment Station Research Reports

Various strategies have been proposed to mitigate potential risk of porcine epidemic diarrhea virus (PEDV) transmission via feed and feed ingredients. Wet decontamination has been found to be the most effective decontamination of feed mill surfaces; however, this is not practical on a commercial feed production-scale. Another potential mitigation strategy, easier to implement, would be using chemically-treated rice hulls flushed through the feed manufacturing equipment. The objective of this experiment was to determine the impact of MCFA- or formaldehyde-treated rice hull flush batches as potential PEDV mitigation strategies during feed manufacturing. Feed without evidence of PEDV RNA contamination was inoculated ...


Evaluating The Impact Of Vevovitall And/Or Crina As Potential Porcine Epidemic Diarrhea Virus Mitigation Strategies As Determined By Polymerase Chain Reaction Analysis And Bioassay, J. T. Gebhardt, J. C. Woodworth, C. K. Jones, M. D. Tokach, J. M. DeRouchey, R. D. Goodband, R. A. Cochrane, C. R. Stark, J. Bergstrom, Phillip Charles Gauger, J. Bai, Qi Chen, Jianqiang Zhang, Rodger G. Main, S. S. Dritz 2016 Kansas State University, Manhattan

Evaluating The Impact Of Vevovitall And/Or Crina As Potential Porcine Epidemic Diarrhea Virus Mitigation Strategies As Determined By Polymerase Chain Reaction Analysis And Bioassay, J. T. Gebhardt, J. C. Woodworth, C. K. Jones, M. D. Tokach, J. M. Derouchey, R. D. Goodband, R. A. Cochrane, C. R. Stark, J. Bergstrom, Phillip Charles Gauger, J. Bai, Qi Chen, Jianqiang Zhang, Rodger G. Main, S. S. Dritz

Kansas Agricultural Experiment Station Research Reports

Feed and feed ingredients have been shown to be potential vectors of porcine epidemic diarrhea virus (PEDV). Potential strategies to mitigate the risk of disease transmission via feed and feed ingredients would be valuable to the swine and feed milling industries. Therefore, the objective of this experiment was to determine the impact of VevoVitall (5,000 ppm; DSM Nutritional Products Inc., Parsipanny, NJ), CRINA (200 ppm; DSM Nutritional Products Inc., Parsipanny, NJ), and a combination of both products (COMBINATION; 5,000 ppm VevoVitall and 200 ppm CRINA) as feed additives with potential to mitigate the risk of PEDV, in swine ...


Porcine Epidemic Diarrhea Virus Surface Decontamination Strategies Using Chemical Sanitizing To Reduce The Quantity Of Pedv Rna On Feed Manufacturing Surfaces With Environmental Swabbing, M. Muckey, S. S. Dritz, J. C. Woodworth, C. R. Stark, J. Bai, Jianqiang Zhang, Phillip Charles Gauger, Rodger G. Main, C. K. Jones 2016 Kansas State University, Manhattan

Porcine Epidemic Diarrhea Virus Surface Decontamination Strategies Using Chemical Sanitizing To Reduce The Quantity Of Pedv Rna On Feed Manufacturing Surfaces With Environmental Swabbing, M. Muckey, S. S. Dritz, J. C. Woodworth, C. R. Stark, J. Bai, Jianqiang Zhang, Phillip Charles Gauger, Rodger G. Main, C. K. Jones

Kansas Agricultural Experiment Station Research Reports

Porcine Epidemic Diarrhea virus (PEDV) is a possible hazard in feed mills that could impact pig health. If the virus enters a feed mill, it quickly becomes widely distributed and is difficult to decontaminate from surfaces.6,7 The objective of this study was to evaluate a variety of liquid and dry chemical treatments that could be used as sanitizers to reduce the amount of PEDV found on feed manufacturing surfaces in mills. This experiment was replicated 3 times and was designed in a 5 × 10 factorial with main effects of 5 different feed manufacturing surfaces and 10 sanitizing treatments ...


Evaluating The Inclusion Level Of Medium Chain Fatty Acids To Reduce The Risk Of Porcine Epidemic Diarrhea Virus In Complete Feed And Spray-Dried Animal Plasma, R. A. Cochrane, S. S. Dritz, J. C. Woodworth, A. R. Huss, C. R. Stark, M. Saensukjaroenphon, J. M. DeRouchey, M. D. Tokach, R. D. Goodband, J. Bai, Qi Chen, Jianqiang Zhang, Phillip Charles Gauger, Rachel J. Derscheid, Drew Robert Magstadt, Paulo Elias Arruda, Alejandro Ramirez, Rodger G. Main, C. K. Jones 2016 Kansas State University, Manhattan

Evaluating The Inclusion Level Of Medium Chain Fatty Acids To Reduce The Risk Of Porcine Epidemic Diarrhea Virus In Complete Feed And Spray-Dried Animal Plasma, R. A. Cochrane, S. S. Dritz, J. C. Woodworth, A. R. Huss, C. R. Stark, M. Saensukjaroenphon, J. M. Derouchey, M. D. Tokach, R. D. Goodband, J. Bai, Qi Chen, Jianqiang Zhang, Phillip Charles Gauger, Rachel J. Derscheid, Drew Robert Magstadt, Paulo Elias Arruda, Alejandro Ramirez, Rodger G. Main, C. K. Jones

Kansas Agricultural Experiment Station Research Reports

Research has confirmed that chemical treatments, such as medium chain fatty acids (MCFA) and commercial formaldehyde, can be effective to reduce the risk of porcine epidemic diarrhea virus (PEDV) cross-contamination in feed. However, the efficacy of MCFA levels below 2% inclusion is unknown. The objective of this experiment was to evaluate if a 1% inclusion of MCFA is as effective at PEDV mitigation as a 2% inclusion or formaldehyde in swine feed and spray-dried animal plasma (SDAP). Treatments were arranged in a 4 × 2 × 7 plus 2 factorial with 4 chemical treatments: 1) PEDV positive with no chemical treatment, 2 ...


Assessing The Effects Of Medium Chain Fatty Acids And Fat Sources On Porcine Epidemic Diarrhea Virus Viral Rna Stability And Infectivity, R. A. Cochrane, S. S. Dritz, J. C. Woodworth, A. R. Huss, C. R. Stark, M. Saensukjaroenphon, J. M. DeRouchey, M. D. Tokach, R. D. Goodband, J. Bai, Qi Chen, Jianqiang Zhang, Phillip Charles Gauger, Rachel J. Derscheid, Rodger G. Main, C. K. Jones 2016 Kansas State University, Manhattan

Assessing The Effects Of Medium Chain Fatty Acids And Fat Sources On Porcine Epidemic Diarrhea Virus Viral Rna Stability And Infectivity, R. A. Cochrane, S. S. Dritz, J. C. Woodworth, A. R. Huss, C. R. Stark, M. Saensukjaroenphon, J. M. Derouchey, M. D. Tokach, R. D. Goodband, J. Bai, Qi Chen, Jianqiang Zhang, Phillip Charles Gauger, Rachel J. Derscheid, Rodger G. Main, C. K. Jones

Kansas Agricultural Experiment Station Research Reports

Research has confirmed that chemical treatments, such as medium chain fatty acids (MCFA) and commercial formaldehyde, can be effective to reduce the risk of porcine epidemic diarrhea virus (PEDV) cross-contamination in feed. However, the efficacy of individual MCFA levels are unknown. The objective of this study is to compare the efficacy of commercially-available sources of MCFA and other fat sources versus a synthetic custom blend of MCFA to minimize the risk of PEDV cross-contamination as measured by qRT-PCR and bioassay. Treatments were arranged in a 17 × 4 plus 1 factorial with 17 chemical treatments: 1) Positive control with PEDV and ...


Reaction Of Fumonisin With Glucose Prevents Promotion Of Hepatocarcinogenesis In Female F344/N Rats While Maintaining Normal Hepatic Sphinganine/Sphingosine Ratios, Hongjun Liu, Yun Lu, Joseph S. Haynes, Joan E. Cunnick, Patricia A. Murphy, Suzanne Hendrich 2016 Iowa State University

Reaction Of Fumonisin With Glucose Prevents Promotion Of Hepatocarcinogenesis In Female F344/N Rats While Maintaining Normal Hepatic Sphinganine/Sphingosine Ratios, Hongjun Liu, Yun Lu, Joseph S. Haynes, Joan E. Cunnick, Patricia A. Murphy, Suzanne Hendrich

Suzanne Hendrich

The reaction of th e primar y am ine of fumonisin B1 (FB1) with glucose was hypoth esized to detoxify th is mycotoxin. Eight y 10-day-old fema le F344/N rat s were injected intra peritoneally with dieth ylnitrosam ine (DEN; 15 mg/kg of body weig ht). At 4 wee ks of age, th e wean ed rat s were ran domly assigned to one of four tr eatm ent groups with 20 rat s each. At 9 wee ks of age, four rat s from each tr eatm ent group were kille d. At 12 wee ks, anoth ...


Toxicity Of Fusarium Proliferatum-Fermented Nixtamalized Corn-Based Diets Fed To Rats: Effect Of Nutritional Status, Suzanne Hendrich, Kathrine A. Miller, Terrance M. Wilson, Patricia A. Murphy 2016 Iowa State University

Toxicity Of Fusarium Proliferatum-Fermented Nixtamalized Corn-Based Diets Fed To Rats: Effect Of Nutritional Status, Suzanne Hendrich, Kathrine A. Miller, Terrance M. Wilson, Patricia A. Murphy

Suzanne Hendrich

Male F344/ N rats were fed corn, nixtamalized corn, Fusarium proli feratum- fermented (FP) corn to provide 50 mg/kg fumonisin B1 (FB1), or nixtamalized FP corn (NFP), with and without supplemented nutrients. Nixtamalization of FP corn almost completely hydrolyzed FB1 and produced 7-10 mg/kg hydrolyzed fumonisin (HFB1). Relative liver weight was significantly increased in nutrient-supplemented rats fed FP or NFP corn. Plasma cholesterol increased in rats fed FP or NFP corn. Plasma glutamate­ pyruvate transaminase was elevated in allrats fed FP corn and in nutrient-supplemented rats fed NFP corn. All rats fed FP corn and nutrient-supplemented rats fed ...


Excretion Of 14c-Fumonisin B1, 14c-Hydrolyzed Fumonisin B1, And 14c-Fumonisin B1-Fructose In Rats, William R. Dantzer, Joan Hopper, Kathleen Mullin, Suzanne Hendrich, Patricia A. Murphy 2016 Iowa State University

Excretion Of 14c-Fumonisin B1, 14c-Hydrolyzed Fumonisin B1, And 14c-Fumonisin B1-Fructose In Rats, William R. Dantzer, Joan Hopper, Kathleen Mullin, Suzanne Hendrich, Patricia A. Murphy

Suzanne Hendrich

14C-Fumonisin B1 (FB1) was produced by Fusarium proliferatum M-5991 in modified Myro liquid medium and purified to >95% purity with a specific activity of 1.7 mCi/mmol. Nine male and nine female F344/N rats were each dosed by gavage with 0.69 μmol of 14C-FB1, 14C-hydrolyzed FB1, or 14C-FB1-fructose/kg body weight. Urinary excretion of 14C-FB1 and 14C-FB1-fructose was 0.5% and 4.4% of the total dose, respectively, and was similar between male and female rats. Urinary excretion of 14C-hydrolyzed HFB1 was significantly greater (P > 0.05) in female rats as compared with male rats (17.3 ...


Kinetics Of Uv254 Inactivation Of Selected Viral Pathogens In A Static System, T. Cutler, C. Wang, Q. Qin, F. Zhou, K. Warren, K.-J. Yoon, S. J. Hoff, J. Ridpath, J. Zimmerman 2016 Iowa State University

Kinetics Of Uv254 Inactivation Of Selected Viral Pathogens In A Static System, T. Cutler, C. Wang, Q. Qin, F. Zhou, K. Warren, K.-J. Yoon, S. J. Hoff, J. Ridpath, J. Zimmerman

Steven J. Hoff

Aims:  The objective of this study was to estimate UV254 inactivation constants for four viral pathogens: influenza virus type A, porcine respiratory and reproductive syndrome virus (PRRSV), bovine viral diarrhoea virus (BVDV) and reovirus.

Methods and Results:  Viruses in culture medium were exposed to one of nine doses of UV254 and then titrated for infectious virus. Analysis showed that viral inactivation by UV254 was more accurately described by a two-stage inactivation model vs a standard one-stage inactivation model.

Conclusions:  The results provided evidence for the existence of two heterogeneous viral subpopulations among the viruses tested, one highly ...


Prevalence Of Antibodies To Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, And Immunodeficiency Virus And Of Feline Leukemia Virus Antigen And The Interrelationship Of These Viral Infections In Free-Ranging Lions In East Africa, Regina Hofmann-Lehmann, Daniela Fehr, Markus Grob, Muhamed Elgizoli, Craig Packer, Janice S. Martenson, Stephen J. O'Brien, Hans Lutz 2016 University of Zurich

Prevalence Of Antibodies To Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, And Immunodeficiency Virus And Of Feline Leukemia Virus Antigen And The Interrelationship Of These Viral Infections In Free-Ranging Lions In East Africa, Regina Hofmann-Lehmann, Daniela Fehr, Markus Grob, Muhamed Elgizoli, Craig Packer, Janice S. Martenson, Stephen J. O'Brien, Hans Lutz

Stephen O'Brien

While viral infections and their impact are well studied in domestic cats, only limited information is available on their occurrence in free-ranging lions. The goals of the present study were (i) to investigate the prevalence of antibodies to feline calicivirus (FCV), herpesvirus (FHV), coronavirus (FCoV), parvovirus (FPV), and immunodeficiency virus (FIV) and of feline leukemia virus (FeLV) antigen in 311 serum samples collected between 1984 and 1991 from lions inhabiting Tanzania’s national parks and (ii) to evaluate the possible biological importance and the interrelationship of these viral infections. Antibodies to FCV, never reported previously in free-ranging lions, were detected ...


Insertional Polymorphisms Of Endogenous Feline Leukemia Viruses, Alfred L. Roca, William G. Nash, Joan C. Menninger, William J. Murphy, Stephen J. O'Brien 2016 National Cancer Institute at Frederick

Insertional Polymorphisms Of Endogenous Feline Leukemia Viruses, Alfred L. Roca, William G. Nash, Joan C. Menninger, William J. Murphy, Stephen J. O'Brien

Stephen O'Brien

The number, chromosomal distribution, and insertional polymorphisms of endogenous feline leukemia viruses (enFeLVs) were determined in four domestic cats (Burmese, Egyptian Mau, Persian, and nonbreed) using fluorescent in situ hybridization and radiation hybrid mapping. Twenty-nine distinct enFeLV loci were detected across 12 of the 18 autosomes. Each cat carried enFeLV at only 9 to 16 of the loci, and many loci were heterozygous for presence of the provirus. Thus, an average of 19 autosomal copies of enFeLV were present per cat diploid genome. Only five of the autosomal enFeLV sites were present in all four cats, and at only one ...


Genomically Intact Endogenous Feline Leukemia Viruses Of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien 2016 National Cancer Institute at Frederick

Genomically Intact Endogenous Feline Leukemia Viruses Of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien

Stephen O'Brien

We isolated and sequenced two complete endogenous feline leukemia viruses (enFeLVs), designated enFeLV-AGTT and enFeLV-GGAG. In enFeLV-AGTT, the open reading frames are reminiscent of a functioning FeLV genome, and the 5′ and 3′ long terminal repeat sequences are identical. Neither endogenous provirus is genetically fixed in cats but polymorphic, with 8.9 and 15.2% prevalence for enFeLV-AGTT and enFeLV-GGAG, respectively, among a survey of domestic cats. Neither provirus was found in the genomes of related species of the Felis genus, previously shown to harbor enFeLVs. The absence of mutational divergence, polymorphic incidence in cats, and absence in related species ...


Genomic Organization, Sequence Divergence, And Recombination Of Feline Immunodeficiency Virus From Lions In The Wild, Jill Pecon-Slattery, Carrie L. McCracken, Jennifer L. Troyer, Sue VandeWoude, Melody E. Roelke, Kerry Sondgeroth, Christiaan Winterbach, Stephen J. O'Brien 2016 National Cancer Institute at Frederick

Genomic Organization, Sequence Divergence, And Recombination Of Feline Immunodeficiency Virus From Lions In The Wild, Jill Pecon-Slattery, Carrie L. Mccracken, Jennifer L. Troyer, Sue Vandewoude, Melody E. Roelke, Kerry Sondgeroth, Christiaan Winterbach, Stephen J. O'Brien

Stephen O'Brien

Background

Feline immunodeficiency virus (FIV) naturally infects multiple species of cat and is related to human immunodeficiency virus in humans. FIV infection causes AIDS-like disease and mortality in the domestic cat (Felis catus) and serves as a natural model for HIV infection in humans. In African lions (Panthera leo) and other exotic felid species, disease etiology introduced by FIV infection are less clear, but recent studies indicate that FIV causes moderate to severe CD4 depletion.

Results

In this study, comparative genomic methods are used to evaluate the full proviral genome of two geographically distinct FIV subtypes isolated from free-ranging lions ...


Digital Commons powered by bepress