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4,476 full-text articles. Page 1 of 34.

Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova MS, RNDr, PhD, Kusum Rathore 2014 University of Tennessee, Knoxville

Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova Ms, Rndr, Phd, Kusum Rathore

Maria Cekanova MS, RNDr, PhD

Cancer is the term used to describe over 100 diseases that share several common hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the second leading cause of death in the USA. Successful bench-to-bedside translation of basic scientific findings about cancer into therapeutic interventions for patients depends on the selection of appropriate animal experimental models. Cancer research uses animal and human cancer cell lines in vitro to study biochemical pathways in these cancer cells. In this review, we summarize the important animal models of cancer with focus on their advantages and limitations. Mouse cancer models are well known ...


Development Of A Fatal Noncompressible Truncal Hemorrhage Model With Combined Hepatic And Portal Venous Injury In Normothermic Normovolemic Swine, Ujwal R. Yanala, Jason M. Johanning, Iraklis I. Pipinos, Gustavo Larsen, William H. Velander, Mark A. Carlson 2014 University of Nebraska - Lincoln

Development Of A Fatal Noncompressible Truncal Hemorrhage Model With Combined Hepatic And Portal Venous Injury In Normothermic Normovolemic Swine, Ujwal R. Yanala, Jason M. Johanning, Iraklis I. Pipinos, Gustavo Larsen, William H. Velander, Mark A. Carlson

William H. Velander Publications

Noncompressible truncal hemorrhage and brain injury currently account for most early mortality of warfighters on the battlefield. There is no effective treatment for noncompressible truncal hemorrhage, other than rapid evacuation to a surgical facility. The availability of an effective field treatment for noncompressible truncal hemorrhage could increase the number of warfighters salvaged from this frequently-lethal scenario. Our intent was to develop a porcine model of noncompressible truncal hemorrhage with a ,50% one-hour mortality so that we could develop new treatments for this difficult problem. Normovolemic normothermic domestic swine (barrows, 3 months old, 34–36 kg) underwent one of three injury ...


Annotated Bibliography: Attitudes Toward Animal Research (1998-2013), Erich Yahner 2014 Humane Society Institute for Science and Policy

Annotated Bibliography: Attitudes Toward Animal Research (1998-2013), Erich Yahner

Humane Education

No abstract provided.


Evaluation Of Pre-Harvest Screening For Antibiotics And Flunixin Meglumine In Cattle, Shuna A. Jones 2014 University of Nebraska - Lincoln

Evaluation Of Pre-Harvest Screening For Antibiotics And Flunixin Meglumine In Cattle, Shuna A. Jones

Dissertations & Theses in Veterinary and Biomedical Science

Many antibiotics and medications used in the treatment of animals have a withdrawal time; residues are a concern for the meat industry. The most recently published 2009 USDA-FSIS Residue Program Data Report listed 135,389 Inspector-In-Charge-Generated (IICG) residue samples from 43,142,500 beef and dairy cattle inspected that year at harvest (USDA-FSIS 2009a). Of these samples, 1306 contained violative antibiotic residues and 327 violative flunixin meglumine residues. Two classes of antimicrobials comprised over half of the documented violative antimicrobial residues (beta-lactams that include ceftiofur and sulfa drugs that include sulfadimethoxine). While the violative residue rate seems small, violative residues ...


Small Animal Bandaging, Erin Wood 2014 University of Tennessee, Knoxville

Small Animal Bandaging, Erin Wood

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Rabies Vaccination Protocols And Pitfalls, Zenny Ng 2014 University of Tennessee, Knoxville

Rabies Vaccination Protocols And Pitfalls, Zenny Ng

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Chloramphenicol In Horses, Eva McElligot 2014 University of Tennessee, Knoxville

Chloramphenicol In Horses, Eva Mcelligot

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Chronic Colic, Karen McCormick 2014 University of Tennessee, Knoxville

Chronic Colic, Karen Mccormick

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Naso-Gastric And Naso-Esophogeal Feeding Tube Placement, Elise Littleton 2014 University of Tennessee, Knoxville

Naso-Gastric And Naso-Esophogeal Feeding Tube Placement, Elise Littleton

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Rabies, Dog Bites Prevalence, And Legislation, Zenny Ng 2014 University of Tennessee, Knoxville

Rabies, Dog Bites Prevalence, And Legislation, Zenny Ng

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Trauma Patient: Post-Stabilization And Recovery, Amanda Bush 2014 University of Tennessee, Knoxville

Trauma Patient: Post-Stabilization And Recovery, Amanda Bush

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Trauma Patient: Diagnostics, Imaging, And Monitoring, Derek Vanderhoff 2014 University of Tennessee, Knoxville

Trauma Patient: Diagnostics, Imaging, And Monitoring, Derek Vanderhoff

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Small Animal Ecc, Jennifer Herring 2014 University of Tennessee, Knoxville

Small Animal Ecc, Jennifer Herring

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Wow Them With Winning Service, Shawn G. McVey 2014 University of Tennessee, Knoxville

Wow Them With Winning Service, Shawn G. Mcvey

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Case Reports - Equine Hind Limb Lameness, Stacie Boswell 2014 University of Tennessee, Knoxville

Case Reports - Equine Hind Limb Lameness, Stacie Boswell

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Trauma Patient: Initial Assessment, Catheter Placement, And Stabilization, Eric Hilton 2014 University of Tennessee, Knoxville

Trauma Patient: Initial Assessment, Catheter Placement, And Stabilization, Eric Hilton

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Oncology - New Opportunities For Cancer Patients In Clinical Trials, Olya Smrkovski, Maria Cekanova, Claire Cannon 2014 University of Tennessee, Knoxville

Oncology - New Opportunities For Cancer Patients In Clinical Trials, Olya Smrkovski, Maria Cekanova, Claire Cannon

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Skin Grafting In The Horse, Stacie Boswell 2014 University of Tennessee, Knoxville

Skin Grafting In The Horse, Stacie Boswell

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Standing Equine Penile Amputation, Michael Caruso 2014 University of Tennessee, Knoxville

Standing Equine Penile Amputation, Michael Caruso

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


Jerky Toxicity, Linden Craig, Heather Lollar 2014 University of Tennessee, Knoxville

Jerky Toxicity, Linden Craig, Heather Lollar

Veterinary Partners Appreciation Conference (V-PAC)

No abstract provided.


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