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Otorhinolaryngologic Diseases Commons

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A Pilot Study To Investigate Concerns In Patients Undergoing Neck Dissection Surgery, Daniel Sundar Raj Arulananda Doss 2013 The University of Western Ontario

A Pilot Study To Investigate Concerns In Patients Undergoing Neck Dissection Surgery, Daniel Sundar Raj Arulananda Doss

Electronic Thesis and Dissertation Repository

Abstract:

This study investigates concerns in patients undergoing neck dissection surgery. Forty patients were recruited at Pre-surgery, Discharge and 1-month Post-surgery. The Patient Concerns Inventory - Level of Importance questionnaire (PCI-LOI), Shoulder Pain and Disability Index (SPADI), Neck Dissection Impairment Index (NDII) and the University of Washington - Quality of Life questionnaire (UWQOL) were used.

The study identified "Anxiety" at Pre-surgery and "Appearance" at Discharge and 1-month Post-surgery as the important patient concerns. Patients’ concerns were found to change over time. Support for cross-sectional convergent validity of the PCI-LOI was evidenced by significant correlations between the PCI-LOI and the UWQOL (r = -0 ...


Dimethyl Sulfoxide (Dmso) Exacerbates Cisplatin-Induced Sensory Hair Cell Death In Zebrafish (Danio Rerio), Phillip M. Uribe, Melissa A. Mueller, Julia S. Gleichman, Matthew D. Kramer, Qi Wang, Martha Sibrian-Vazquez, Robert M. Strongin, Peter S. Steyger, Douglas A. Contanche, Jonathan I. Matsui 2013 Pomona College

Dimethyl Sulfoxide (Dmso) Exacerbates Cisplatin-Induced Sensory Hair Cell Death In Zebrafish (Danio Rerio), Phillip M. Uribe, Melissa A. Mueller, Julia S. Gleichman, Matthew D. Kramer, Qi Wang, Martha Sibrian-Vazquez, Robert M. Strongin, Peter S. Steyger, Douglas A. Contanche, Jonathan I. Matsui

Cell and Developmental Biology Publications

Inner ear sensory hair cells die following exposure to aminoglycoside antibiotics or chemotherapeutics like cisplatin, leading to permanent auditory and/or balance deficits in humans. Zebrafish (Danio rerio) are used to study drug-induced sensory hair cell death since their hair cells are similar in structure and function to those found in humans. We developed a cisplatin dose-response curve using a transgenic line of zebrafish that expresses membrane-targeted green fluorescent protein under the control of the Brn3c promoter/enhancer. Recently, several small molecule screens have been conducted using zebrafish to identify potential pharmacological agents that could be used to protect sensory ...


Is The Use Of Intestinal Helminths Safe And Effective In The Treatment Of Allergic Rhinitis?, Tanner McCalley 2013 Philadelphia College of Osteopathic Medicine

Is The Use Of Intestinal Helminths Safe And Effective In The Treatment Of Allergic Rhinitis?, Tanner Mccalley

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this EBM review is to determine whether the use of intestinal helminths is safe and effective in the treatment of allergic rhinitis.

STUDY DESIGN: Review of three English language, blinded randomized controlled trials from 2009, 2010, and 2010.

DATA SOURCE: Randomized, controlled, blinded trials comparing the use of intestinal helminths versus visually matched placebo as a treatment for allergic rhinitis found using PubMed and Ovid databases.

OUTCOMES MEASURED: Several different systems were used to evaluate the symptoms or occurrence of AR. Bager et al.2010 uses symptom scores of AR scale of 0 to 3. Feary ...


Review Of Ear Health And Hearing Among Indigenous Australians, Jane F. Burns, Neil J. Thomson 2013 Edith Cowan University

Review Of Ear Health And Hearing Among Indigenous Australians, Jane F. Burns, Neil J. Thomson

ECU Publications 2013

Indigenous Australians experience some of the highest levels of ear disease and hearing loss in the world, with rates up to ten times more than those for non-Indigenous Australians [4]. Children and adolescents are particularly vulnerable to ear infections. The most common ear disease among Indigenous children is otitis media (OM), which is inflammation/infection of the middle ear typically caused by bacterial and viral pathogens. Indigenous children living in urban, rural and, particularly, remote areas, are more likely than their non-Indigenous counterparts to have OM at younger ages, more often, at a greater level of severity, and with more ...


Repetitive Transcranial Magnetic Stimulation Used For Tinnitus Suppression: A Voxel-Based Morphometry Study, Lauren E. Laitman 2011 Union College - Schenectady, NY

Repetitive Transcranial Magnetic Stimulation Used For Tinnitus Suppression: A Voxel-Based Morphometry Study, Lauren E. Laitman

Honors Theses

Tinnitus is a debilitating disorder with unknown underlying mechanisms, often induced by loud noises. Tinnitus symptoms include the conscious perception of constant sound absent an external source. This study sought to determine effectiveness of treatment with repetitive transcranial magnetic stimulation (rTMS), and to use voxel-based morphometry (VBM) to identify treatment related neuronal reorganization. One hertz rTMS was delivered for 20 minutes on each of 5 consecutive days. Tinnitus suppression was measured with the Tinnitus Handicap Questionnaire (THQ), and VBM was carried out on structural Magnetic Resonance images collected before and after sham-treatment and rTMS. Findings indicate the effectiveness of rTMS ...


The Effectiveness And Safety Of Antibiotic Treatment In Healing Tympanic Membrane Perforation In Aboriginal Children, Shannon M. Rice 2011 Philadelphia College of Osteopathic Medicine

The Effectiveness And Safety Of Antibiotic Treatment In Healing Tympanic Membrane Perforation In Aboriginal Children, Shannon M. Rice

PCOM Physician Assistant Studies Student Scholarship

The objective of this systematic review is to determine whether or not antibiotic treatment is safe and effective in healing tympanic membrane (TM) perforation in Aboriginal children diagnosed with chronic suppurative otitis media and otitis media with effusion less than 16 years of age.


Topical Analgesia For Acute Otitis Media, Ruth Foxlee, Ann-Charlotte Johansson, Jessika Wejfalk, Liz Dooley, Chris Del Mar 2010 University of York

Topical Analgesia For Acute Otitis Media, Ruth Foxlee, Ann-Charlotte Johansson, Jessika Wejfalk, Liz Dooley, Chris Del Mar

Liz Dooley

Background Acute otitis media (AOM) is a spontaneously remitting disease for which pain is the most distressing symptom. Antibiotics are now known to have less benefit than previously assumed. Objectives To assess the effectiveness of topical analgesia for AOM. Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 2, 2006), MEDLINE (1966 to May Week 3 2006), EMBASE (1990 to December 2005) and LILACS (1982 to September 2005) without language restriction, and the reference lists of articles. We also contacted manufacturers and authors. Selection criteria Double-blind randomised or quasi-randomised controlled trials comparing an ...


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