Treating Cytokine Storm In Patients With Covid-19,
2022
University of Louisville
Treating Cytokine Storm In Patients With Covid-19, Ahmed Abdelhaleem, Deekshitha Turaka, Shameera Shaik Masthan, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Agenda: Umccts Research Symposium 2022,
2022
UMass Chan Medical School
Agenda: Umccts Research Symposium 2022, Umass Center For Clinical And Translational Science
UMass Center for Clinical and Translational Science Research Symposium
Agenda for the UMass Center for Clinical and Translational Science Research Symposium held virtually on Friday, June 10, 2022.
Umccts Newsletter, June 2022,
2022
UMass Chan Medical School
Umccts Newsletter, June 2022, Umass Center For Clinical And Translational Science
UMass Center for Clinical and Translational Science Newsletter
This is the June 2022 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.
Primary Cilia Of The Cardiac Neural Crest & Hedgehog-Mediated Mechanisms Of Congenital Heart Disease,
2022
University of Maine
Primary Cilia Of The Cardiac Neural Crest & Hedgehog-Mediated Mechanisms Of Congenital Heart Disease, Lindsey A. Fitzsimons
Electronic Theses and Dissertations
Elimination of primary cilia in cardiac neural crest cell (CNCC) progenitors is hypothesized to cause a variety of congenital heart defects (CHDs), including atrioventricular septal defects, and malformations of the developing cardiac outflow tract. We present an in vivo model of CHD resulting from the conditional elimination of primary cilia from CNCC using multiple, Wnt1:Cre-loxP, neural crest-specific systems, targeting two distinctive, but critical, primary cilia structural genes: Intraflagellar transport protein 88 (Ift88) or kinesin family member 3A (Kif3a). CNCC loss of primary cilia leads to widespread CHD, where homozygous mutant embryos (MUT) display a variety of outflow tract malformations ...
Antimicrobial Stewardship Meets Transitions Of Care: Defining Length Of Therapy For Community-Acquired Pneumonia (Cap),
2022
Infirmary Health
Antimicrobial Stewardship Meets Transitions Of Care: Defining Length Of Therapy For Community-Acquired Pneumonia (Cap), Christopher Whitman, Sarah E. Moore Pharmd, Matthew Song Pharmd, Bcidp, Brian C. Bohn Pharmd, Bcidp, Ashley M. Wilde
The University of Louisville Journal of Respiratory Infections
Introduction: Hospital-based antimicrobial stewardship efforts have traditionally focused on inpatient settings. Antibiotic prescribing at discharge is often an overlooked area of focus for antimicrobial stewardship programs. Discharge prescribing optimization is necessary to combat antibiotic overuse.
Methods: This was an observational, retrospective cohort study at a four–adult community hospital system. Four hundred adult patients admitted with community-acquired pneumonia and discharged with antibiotics were included. The primary outcome was overall (inpatient and discharge) antibiotic length of therapy. The secondary outcome was percentage of patients discharged on a fluoroquinolone who had not received one in the hospital. Descriptive statistics were utilized.
Results ...
Covid-19 Case Complicated With Organizing Pneumonia And Pneumothorax: Correspondence,
2022
Orlando VA
Covid-19 Case Complicated With Organizing Pneumonia And Pneumothorax: Correspondence, Hammad A. Bhatti, Minh Q. Ho
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Covid-19, Vaccination, And Heart Transplantation,
2022
University of Louisville
Covid-19, Vaccination, And Heart Transplantation, Forest W. Arnold
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Umccts Newsletter, May 2022,
2022
UMass Chan Medical School
Umccts Newsletter, May 2022, Umass Center For Clinical And Translational Science
UMass Center for Clinical and Translational Science Newsletter
This is the May 2022 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.
Hdac6 Inhibition Reverses Long-Term Doxorubicin-Induced Cognitive Dysfunction By Restoring Microglia Homeostasis,
2022
The Texas Medical Center Library
Hdac6 Inhibition Reverses Long-Term Doxorubicin-Induced Cognitive Dysfunction By Restoring Microglia Homeostasis, Blake Mcalpin
The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Dissertations and Theses (Open Access)
One in 8 women in the US will be diagnosed with breast cancer. Currently, doxorubicin is one of the most effective chemotherapies for breast cancer. Unfortunately, up to 60% of survivors report long-term chemotherapy-induced cognitive dysfunction (CICD) characterized by deficits in working memory, processing speed, and executive functioning. Currently, no interventions for CICD have been approved by the US Food and Drug Administration. I show here that a 14-day treatment with a blood-brain barrier permeable histone deacetylase 6 (HDAC6) inhibitor successfully reverses long-term CICD following a therapeutic doxorubicin dosing schedule in female mice, as assessed by the puzzle box test ...
A Survey To Highlight Areas Of Focus For Patient Care In Settings Utilizing Medical Interpretation,
2022
East Tennessee State University
A Survey To Highlight Areas Of Focus For Patient Care In Settings Utilizing Medical Interpretation, Azayzel Deregis
Undergraduate Honors Theses
This thesis recounts my personal experience working as a volunteer medical interpreter for the Language and Culture Resource Center at East Tennessee State University. The result of my time spent volunteering as a medical interpreter, shadowing professional medical interpreters, and witnessing patient-provider interactions during interpreted sessions was an inspiration to study medical interpretation further and delve into the challenges faced by patients who require medical interpreters. During my time researching this topic, I found that the United States is severely lacking in Spanish medical interpreters—with some healthcare facilities employing no medical interpreters—even though the size of the Hispanic ...
Development And Application Of 3d Kinematic Methodologies For Biomechanical Modelling In Adaptive Sports And Rehabilitation,
2022
Clemson University
Development And Application Of 3d Kinematic Methodologies For Biomechanical Modelling In Adaptive Sports And Rehabilitation, Anne Marie Severyn
All Dissertations
Biomechanical analysis is widely used to assess human movement sciences, specifically using three-dimensional motion capture modelling. There are unprecedented opportunities to increase quantitative knowledge of rehabilitation and recreation for disadvantaged population groups. Specifically, 3D models and movement profiles for human gait analysis were generated with emphasis on post-stroke patients, with direct model translation to analyze equivalent measurements while horseback riding in use of the alternative form of rehabilitation, equine assisted activities and therapies (EAAT) or hippotherapy (HPOT). Significant improvements in gait symmetry and velocity were found within an inpatient rehabilitation setting for patients following a stroke, and the developed movement ...
Insulin Therapy Versus Oral Sitagliptin For Treatment Of Latent Autoimmune Diabetes In Adults,
2022
Wayne State University
Insulin Therapy Versus Oral Sitagliptin For Treatment Of Latent Autoimmune Diabetes In Adults, Sarah Nasser
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Hals IK, Fiskvik Fleiner H, Reimers N, et al. Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial. Diabetes Obes Metab. 2019;21(10):2219-2227. https://doi.org/10.1111/dom.13797
for a patient with an aversion to needles.
Indications For Esophagogastroduodenoscopy In Anemic Patients Without Overt Signs Of Upper Gastrointestinal Bleeding,
2022
Wayne State University
Indications For Esophagogastroduodenoscopy In Anemic Patients Without Overt Signs Of Upper Gastrointestinal Bleeding, Geoffrey M. Ginter
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Majid S, Salih M, Wasaya R, Jafri W. Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms. BMC Gastroenterol. 2008;8:52. https://doi.org/10.1186/1471-230X-8-52
for a patient with a complicated presentation of severe anemia
Exercise Therapy Improves Quality Of Life In Patients With Postural Orthostatic Tachycardia Syndrome (Pots),
2022
Wayne State University School of Medicine
Exercise Therapy Improves Quality Of Life In Patients With Postural Orthostatic Tachycardia Syndrome (Pots), Heya Batah, Scott L. Baughan
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using
George SA, Bivens TB, Howden EJ, et al. The international POTS registry: Evaluating the efficacy of an exercise training intervention in a community setting. Heart Rhythm. 2016;13(4):943-950. https://doi.org/10.1016/j.hrthm.2015.12.012
for exercise efficacy in patients with POTS.
Sotrovimab: Neutralizing Antibody To Combat Covid-19,
2022
Menoufia University
Sotrovimab: Neutralizing Antibody To Combat Covid-19, Aya Allam, Steven Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Are Antipyretic Medications Compatible With Sars-Cov-2 Vaccines?,
2022
University of Louisville
Are Antipyretic Medications Compatible With Sars-Cov-2 Vaccines?, Sharanya S E Santhi, Niguma Rayamajhi, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Leptospirosis Presenting As Diffuse Alveolar Hemorrhage,
2022
Alejandro Posadas National Hospital, Buenos Aires, Argentina
Leptospirosis Presenting As Diffuse Alveolar Hemorrhage, Alejandra González, Paola Alvarez, Mariano Fielli, Analia Santos, Neil Gomez Querales, Elkin Rodriguez Arzuaga
The University of Louisville Journal of Respiratory Infections
Diffuse alveolar hemorrhage (DAH) syndrome has a mortality rate of 30 to 60%. A 15-year-old male patient presented with a seven-day abdominal pain, vomiting, non-dysenteric diarrhea, conjunctival injection, and fever. Chest radiography revealed bilateral interstitial infiltrates predominating in the lower left lobe. The patient’s condition worsened within hours, with the development of massive hemoptysis, acute respiratory distress syndrome (ARDS), arterial hypotension, and hematocrit decline requiring mechanical ventilation. A chest computed tomography (CT) showed ground-glass opacities with consolidation areas in lower lobes, diffuse tree-in-bud opacities, and centrilobular nodules. A bronchoscopy was conducted without endoluminal lesions and bronchoalveolar lavage (BAL) consistent ...
Mucormycosis: Covid-19 And Corticosteroids,
2022
Gujarat Medical Education and Research Society Medical College
Mucormycosis: Covid-19 And Corticosteroids, Mittal Savaliya, Nivedita Jha, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Association Of Trends In Child Undernutrition And Implementation Of The National Rural Health Mission In India: A Nationally Representative Serial Cross-Sectional Study On Data From 1992 To 2015,
2022
UMass Chan Medical School
Association Of Trends In Child Undernutrition And Implementation Of The National Rural Health Mission In India: A Nationally Representative Serial Cross-Sectional Study On Data From 1992 To 2015, Apurv Soni, Nisha Fahey, Zulfiqar Bhutta, Wenjun Li, Tiffany A. Moore Simas, Somashekhar Nimbalkar, Jeroan J. Allison
UMass Center for Clinical and Translational Science Supported Publications
BACKGROUND: India launched the National Rural Health Mission (NRHM) in 2005 to strengthen its primary healthcare system in high-focus and northeast-focus states. One of the NRHM objectives was to reduce child undernutrition in India.
METHODS AND FINDINGS: We used data from 1992, 1998, 2005, and 2015 National Family Health Survey (NFHS) of India to evaluate trends in child undernutrition prevalence before and after NRHM and across different categories of focus states. Stunting, Wasting, and Comprehensive Index of Anthropometric Failure (CIAF) were assessed using the World Health Organization (WHO) growth curves to assess chronic, acute, and overall undernutrition. The study included ...
Umccts Newsletter, April 2022,
2022
UMass Chan Medical School
Umccts Newsletter, April 2022, Umass Center For Clinical And Translational Science
UMass Center for Clinical and Translational Science Newsletter
This is the April 2022 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.