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The Benefits Of Art Therapy On Stress And Anxiety Of Oncology Patients During Treatment, Helen Shiepe 2023 Lesley University

The Benefits Of Art Therapy On Stress And Anxiety Of Oncology Patients During Treatment, Helen Shiepe

Expressive Therapies Capstone Theses

Within the last ten years research on art therapy and its positive impact on oncology patients’ stress and anxiety during treatment has been minimal. Oncology patients whether they are children or adults when diagnosed experience similar reactions due to their diagnosis, treatment, and in some cases end of life care. The current question is whether or not art therapy does have a positive impact on decreasing the stress and anxiety with oncology patients while undergoing treatment. Deane, Fitch & Carmen (2000), discussed art therapy as a healing art that is “intended to integrate physical, emotional, and spiritual care by facilitating creative ...


Small Extracellular Vesicle-Mediated Itgb6 Sirna Delivery Downregulates The Αvβ6 Integrin And Inhibits Adhesion And Migration Of Recipient Prostate Cancer Cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, Lucia R Languino 2022 Thomas Jefferson University

Small Extracellular Vesicle-Mediated Itgb6 Sirna Delivery Downregulates The Αvβ6 Integrin And Inhibits Adhesion And Migration Of Recipient Prostate Cancer Cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, Lucia R Languino

Department of Cancer Biology Faculty Papers

The αVβ6 integrin, an epithelial-specific cell surface receptor absent in normal prostate and expressed during prostate cancer (PrCa) progression, is a therapeutic target in many cancers. Here, we report that transcript levels of ITGB6 (encoding the β6 integrin subunit) are significantly increased in metastatic castrate-resistant androgen receptor-negative prostate tumors compared to androgen receptor-positive prostate tumors. In addition, the αVβ6 integrin protein levels are significantly elevated in androgen receptor-negative PrCa patient derived xenografts (PDXs) compared to androgen receptor-positive PDXs. In vitro, the androgen receptor-negative PrCa cells express high levels of the αVβ6 integrin compared to androgen receptor-positive PrCa cells. Additionally, expression ...


Utility Of The Motivation To Change Lifestyle And Health Behaviors For Dementia Risk Reduction Scale (Mclhb-Drr) Based On A North American Sample, Angelina E. Witbeck 2022 National Louis University

Utility Of The Motivation To Change Lifestyle And Health Behaviors For Dementia Risk Reduction Scale (Mclhb-Drr) Based On A North American Sample, Angelina E. Witbeck

Dissertations

As the population ages, the prevalence rates of dementia continue to increase. Without a cure or promising treatment for dementia, the best course of lowering the prevalence rates of dementia is through preventative measures. Through an electronic survey, the study utilized the MCLHB-DRR scale to determine whether (1) gender, age, educational background, and socioeconomic status will impact the motivational factors to change lifestyle and health behaviors to reduce the risk of developing dementia and (2) direct experiences with individuals that have a dementia diagnosis are likely to impact one's motivational factors to change lifestyle and health behaviors to reduce ...


Oral Administration Of Injectable Vitamin K1 In Brodifacoum Intoxication, Yen-Jung Chu, Jing-Hua Lin, Dong-Zong Hung 2022 China Medical University Hospital

Oral Administration Of Injectable Vitamin K1 In Brodifacoum Intoxication, Yen-Jung Chu, Jing-Hua Lin, Dong-Zong Hung

BioMedicine

Brodifacoum is a highly potent and long-acting anticoagulant rodenticide (LAAR). LAAR poisoning possibly leads to long term bleeding problems and needs vitamin K1 treatment for several months. Due to economic concern, tablet preparation of vitamin K1 was not available in most of the countries, including Taiwan. In literature, few reports had pointed out that injectable form of vitamin K could be used orally in patients on anticoagulant therapy with supratherapeutic state. Here, we reported a family with 3 members suffering from brodifacoum poisoning with severe coagulopathy needed to prolong hospitalization for intravenous vitamin K1 therapy, and successfully managed with injectable ...


Comparison Between The Analytical Sensitivity And Clinical Performance Of Two Cobas Sars-Cov-2 Tests Based On High-Throughput And Point-Of-Care Systems, Tsai-Hsiu Lin, Ngoc-Niem Bui, Yu-Chang Chang, Li-Yun Hsu, Yang-Di Su, Chieh-Min Chang, Wei-An Hong, Uyen Nguyen Phuong Le, Su-Hua Huang, Cheng-Wen Lin 2022 China Medical University

Comparison Between The Analytical Sensitivity And Clinical Performance Of Two Cobas Sars-Cov-2 Tests Based On High-Throughput And Point-Of-Care Systems, Tsai-Hsiu Lin, Ngoc-Niem Bui, Yu-Chang Chang, Li-Yun Hsu, Yang-Di Su, Chieh-Min Chang, Wei-An Hong, Uyen Nguyen Phuong Le, Su-Hua Huang, Cheng-Wen Lin

BioMedicine

Objectives: This study examined analytical sensitivity, specificity, and the clinical performance in detecting SARS-CoV-2 of the Cobas SARS-CoV-2 Test based on the high-throughput Cobas 6800 system and the Cobas SARS-CoV-2 & Flu A/B Test based on the point-of-care cobas Liat system.

Methods: The commercial reagents containing SARS-CoV-2 RNA subgenomes were diluted for assessing the sensitivity of the RT-qPCR assay. 385 nasopharyngeal swab specimens taken from contacts of COVID-19 cases were tested for the SARS-CoV-2 detection with both Cobas SARS-CoV-2 Tests.

Results: In analytical sensitivity assays, the Cobas SARS-CoV-2 & Flu A/B Test on the Liat system had a lower limit ...


Crude Extract Of Desmodium Gangeticum Process Anticancer Activity Via Arresting Cell Cycle In G1 And Modulating Cell Cycle-Related Protein Expression In A549 Human Lung Carcinoma Cells, Yuh-Fung Chen, Yi-Hsien Lu, Huei-Yann Tsai 2022 China Medical University - Taiwan

Crude Extract Of Desmodium Gangeticum Process Anticancer Activity Via Arresting Cell Cycle In G1 And Modulating Cell Cycle-Related Protein Expression In A549 Human Lung Carcinoma Cells, Yuh-Fung Chen, Yi-Hsien Lu, Huei-Yann Tsai

BioMedicine

Background: Desmodium gangeticum (L.)DC., which belongs to the Leguminosae family, has been used in Taiwan and other subtropical countries as an external medicine to remove blood stasis, activate blood circulation, and reduce inflammation. It has been reported to have antioxidant effects and improve inflammatory responses in rats stimulated by pro-inflammatory agents and induced gastric ulcers in experimental animals over the past few decades. This plant has also been used to treat parasitic infections, but there are no reports regarding its effects on lung cancer. Therefore, this study attempted to investigate its water crude extract (in abbreviation DG) on lung ...


Serum Alpha-1-Antitrypsin Level In The Severity Prognosis Of Systemic Lupus Erythematosus Patients: Systematic Exploration Of Novel Biomarker, Supaporn Khamchun Dr., Chunyanuch Thakaeng Miss, Rattikan Na Lampang Miss 2022 Department of Medical Technology, School of Allied Health Sciences, University of Phayao, Thailand; Unit of Excellence in Integrative Molecular Biomedicine, School of Allied Health Sciences, University of Phayao, Thailand

Serum Alpha-1-Antitrypsin Level In The Severity Prognosis Of Systemic Lupus Erythematosus Patients: Systematic Exploration Of Novel Biomarker, Supaporn Khamchun Dr., Chunyanuch Thakaeng Miss, Rattikan Na Lampang Miss

BioMedicine

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affecting multi-organs injury and failure. The rapid, precision, and specificity prognosis by laboratory investigations could prevent active stage and severity in the disease.

Aims: To systematically explore and investigate the candidate serum protein for development into the novel biomarker for severity prognosis of SLE patients.

Methods: The proteins previously reported in abnormal level in serum/plasma of SLE patients since 2014-2020 were comprehensive collected. Thereafter, these serum proteins that found in other diseases were excluded. The association with molecules related to SLE severity of these candidate proteins were then ...


Analysis Of Pap Smear Screening Factors Using Artificial Neural Network (Anns), Elaheh Allahyari, Mitra Moodi, Zoya Tahergorabi 2022 Birjand University of Medical Sciences

Analysis Of Pap Smear Screening Factors Using Artificial Neural Network (Anns), Elaheh Allahyari, Mitra Moodi, Zoya Tahergorabi

BioMedicine

Introduction: cervical cancer is ranked as the third most prevalent cancer to affect women over the world and a Pap smear seems to be the single most critical intervention to prevent cervical cancer.

Aim: In the present study, the effects of demographic factors (age, education level, job, income level, marriage age, pregnancy, child number, breastfeeding, and menopause), insurance type, disease history (sonography and mammography, breast problem, and cancer) and cancer information on Pap smear screening behavior stage of change were investigated and modeled using an artificial neural network model (ANN).

Materials and Methods: Data were collected from a descriptive-analytical cross-sectional ...


Fibroblast Growth Factor Receptor 1-Bound Extracellular Vesicle As Novel Therapy For Osteoarthritis, Bryan Gervais de Liyis, John Nolan, Made Agus Maharjana 2022 Udayana University, Bali

Fibroblast Growth Factor Receptor 1-Bound Extracellular Vesicle As Novel Therapy For Osteoarthritis, Bryan Gervais De Liyis, John Nolan, Made Agus Maharjana

BioMedicine

Osteoarthritis (OA) is a joint condition that causes significant impairment of the chondrocyte. The gradual degradation of the cartilage lining of one or more freely moving joints, as well as persistent inflammation, are the causes of osteoarthritis. Current medication focus on alleviating symptoms rather than curing the condition. The aim of this review is to evaluate the potential use of fibroblast growth factor receptor 1 extracellular vesicle as novel therapy for osteoarthritis. This review article was completed by searching for the keywords “Fibroblast Growth Factor Receptor 1”, “Extracellular Vesicle”, and “Osteoarthritis” in various journals in several search engines. Of the ...


Intouch March 23, 2022, New York Medical College 2022 Touro College and University System

Antigen Staining For Detection Of Muc13 And Muc16 Expression In Carcinoma Tissue, Jose A. Benitez 2022 The University of Texas Rio Grande Valley

Antigen Staining For Detection Of Muc13 And Muc16 Expression In Carcinoma Tissue, Jose A. Benitez

MEDI 9331 Scholarly Activities Clinical Years

MUC13 and MUC16 are epithelial expressed proteins implicated in various carcinomas. Overexpression of these biomarkers appear to play a role in tumor growth; this discovery has paved a road for multiple studies discussing the potential of targeting mucin proteins and optimize immunotherapy approaches against carcinomas. Our study serves to investigate the level of expression of MUC13 and MUC16 in cancerous and normal tissue and to discuss the implications our findings may have for the utilization of these biomarkers for cancer therapy.


A Within-Host Modeling Framework For Sars-Cov-2 Infection To Support Vaccine Strategies, Morgan Rose, Rachel Jennings, Jeffry Schroeter 2022 Applied Research Associates, Inc.

A Within-Host Modeling Framework For Sars-Cov-2 Infection To Support Vaccine Strategies, Morgan Rose, Rachel Jennings, Jeffry Schroeter

Biology and Medicine Through Mathematics Conference

No abstract provided.


Study Of Cardiovascular Dynamics During Graded Head-Up Tilt Test In The Young With Syncope Tendency, Martin A. Miranda Sr 2022 Pontificia Universidad Catolica de Chile

Study Of Cardiovascular Dynamics During Graded Head-Up Tilt Test In The Young With Syncope Tendency, Martin A. Miranda Sr

Biology and Medicine Through Mathematics Conference

No abstract provided.


Cathelicidin Anti-Microbial Peptide (Camp) Is Toxic During Neonatal Influenza Virus Infection, Nneka Ugwu 2022 Tower Health

Cathelicidin Anti-Microbial Peptide (Camp) Is Toxic During Neonatal Influenza Virus Infection, Nneka Ugwu

St. Chris Research Day

No abstract provided.


Hospital Costs Of Post-Operative Delirium: A Systematic Review, Md. Parvez Mosharaf, Khorshed Alam, Nicholas Ralph, Jeff Gow 2022 University of Rajshahi

Hospital Costs Of Post-Operative Delirium: A Systematic Review, Md. Parvez Mosharaf, Khorshed Alam, Nicholas Ralph, Jeff Gow

Journal of Perioperative Nursing

Aims: In this systematic review, the primary aim is to investigate the hospital cost burden attributed to post-operative delirium (POD). A secondary aim is to examine how patient length of stay (LOS) in hospital varies across the selected studies.

Background: POD is a common occurrence after major surgery and leads to serious medical complications. It is associated with increased morbidity and double the risk of mortality from surgery compared to non-delirious patients. POD increases patient LOS in hospital and increases the economic burden on patients and the health system.

Design: A systematic review was conducted.

Method: Published articles in English ...


Intouch May 16, 2022, New York Medical College 2022 Touro College and University System

A Preliminary Investigation Of Neuroantibody Levels, Prevalence, And Environmental Factors In Patients With Neurological Dysfunction, Jihan Azar 2022 American University in Cairo

A Preliminary Investigation Of Neuroantibody Levels, Prevalence, And Environmental Factors In Patients With Neurological Dysfunction, Jihan Azar

Theses and Dissertations

Nervous system damage comprises a large proportion of diseases worldwide. It is also the most difficult to diagnose. Biomarkers for nervous system damage are needed in order to diagnose these diseases early enough to allow for intervention. In this study, we recruited patients from two Egyptian hospitals with MCI, ET and NMS and health references. Serum autoantibody levels against neural proteins and heavy metals were analyzed and compared. Immunoglobulin G (IgG) antibodies against neurofilament H (NFH), Glial Fibrillary Acidic Protein (GFAP), Myelin Basic Protein (MBP) and alpha synuclein (a-SYN) and Immunoglobulin M (IgM) antibody against neurofilament light (NFL) were among ...


Intouch May 9, 2022, New York Medical College 2022 Touro College and University System

Reno-Protective And Immune Effects Of Growth Differentiation Factor 15 In Obesity-Related Kidney Disease, Jessie T. Sullivan 2022 University of South Dakota

Reno-Protective And Immune Effects Of Growth Differentiation Factor 15 In Obesity-Related Kidney Disease, Jessie T. Sullivan

Honors Thesis

According to the World Health Organization, worldwide obesity has tripled since 1975 and is still on the rise, putting people at a higher risk of some cardiovascular diseases and kidney disease. Growth differentiation factor 15 (GDF15) is a stress-responsive cytokine that has been studied recently for its role in multiple biological processes and diseases. The member of the transforming growth factor beta (TGF-b) family has been investigated as a therapeutic agent and biomarker for obesity and associated cardiovascular diseases, stroke, diabetes, osteoarthritis, cancer, and kidney disease. Studies have shown the anti-inflammation, anti-obesity, and anti-diabetic effects of GDF15, but few have ...


Admission Pao2 And Mortality Among Pediatric Icu Patients And Critically Ill Subgroups, Cara Holton 2022 Children's Mercy Hospital

Admission Pao2 And Mortality Among Pediatric Icu Patients And Critically Ill Subgroups, Cara Holton

Research Days

Watch recording of live presentation

Background and Objectives: Studies analyzing the association between hyperoxia and mortality in critically ill pediatric patients and those admitted after cardiac arrest are conflicting and limited by small sample sizes. The aim of this study is to evaluate the association between PaO2 on admission to the pediatric ICU and mortality in a heterogeneous, multicenter cohort and among subgroups of critically ill patients.

Methods/Design: A retrospective cohort study was conducted using data from Virtual Pediatric Systems (VPS) database. VPS is a clinical pediatric critical care database with over 135 participating hospitals in North America. All ...


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