The Association Of Lower Medication Adherence And Increased Medical Spending,
2022
University of Nebraska Medical Center
The Association Of Lower Medication Adherence And Increased Medical Spending, Ryan A. Fuchs
Capstone
Medical prescribing is a common occurrence in daily clinical practice. According to the Centers for Disease Control and Prevention, in 2015-2016 45.8% of the U.S. population used prescription drugs in the past 30 days. (CDC, 2019) Although drug therapy can be effective in treating disease, full benefits are often not realized because many patients do not take their medications as prescribed. There is quite a bit of research out there about non-adherence to medication. Some studies focus on the financial impacts of non-adherence, but most of the studies examine the reasons for medication non-adherence. A gap exists in ...
A Small Peptide Increases Drug Delivery In Human Melanoma Cells,
2022
Chapman University
A Small Peptide Increases Drug Delivery In Human Melanoma Cells, Shirley Tong, Shaban Darwish, Hanieh Hossein Nejad Ariani, Kate Alison Lozada, David Salehi, Maris A. Cinelli, Richard B. Silverman, Kamaljit Kaur, Sun Yang
Pharmacy Faculty Articles and Research
Melanoma is the most fatal type of skin cancer and is notoriously resistant to chemotherapies. The response of melanoma to current treatments is difficult to predict. To combat these challenges, in this study, we utilize a small peptide to increase drug delivery to melanoma cells. A peptide library array was designed and screened using a peptide array-whole cell binding assay, which identified KK-11 as a novel human melanoma-targeting peptide. The peptide and its D-amino acid substituted analogue (VPWxEPAYQrFL or D-aa KK-11) were synthesized via a solid-phase strategy. Further studies using FITC-labeled KK-11 demonstrated dose-dependent uptake in human melanoma cells. D-aa ...
Interrogating Race And Place-Based Inequities In Hiv And Covid-19,
2022
University of Nebraska Medical Center
Interrogating Race And Place-Based Inequities In Hiv And Covid-19, Rohan Khazanchi
MD Honors Theses
Over the last four years, I have developed a research focus examining the intersections of race, place, and health. My M.D. Honors Thesis reflects a snapshot of these efforts. In this collection of brief research reports, I leverage area-based measures to investigate structural inequities in three contexts: the HIV epidemic in our hyperlocal community, the early stages of the COVID-19 pandemic, and clinical trials for novel COVID-19 therapeutics. I apply novel social epidemiologic tools to measure and explore disparate outcomes. And, in reflecting upon my findings, I discuss concrete implications for clinicians, researchers, and policymakers alike.
Chapter 1: Neighborhood-Level ...
The Use Of Nebulizer Medications As A Possible Treatment For Covid-19,
2022
Murray State University
The Use Of Nebulizer Medications As A Possible Treatment For Covid-19, Jacob Kaufman
Honors College Theses
For the past few years, the COVID-19 pandemic has been the focal point in healthcare and research. This disease has permanently changed daily life and left a historic impact on the world. Most people have felt the effects of this pandemic either directly, via infection, or indirectly, via change in workflow, financial impact, etc. The main question for this virus still remains today; how do we treat this illness effectively? While many ideas are being tested and suggested, a definite answer has yet to be procured. Vaccine rates are climbing on a daily basis, serving as the first and most ...
A State-Wide Education Program On Opioid Use Disorder: Influential Community Members' Knowledge, Beliefs, And Opportunities For Coalition Development,
2022
Auburn University Harrison College of Pharmacy
A State-Wide Education Program On Opioid Use Disorder: Influential Community Members' Knowledge, Beliefs, And Opportunities For Coalition Development, Lindsey Hohmann, Haley Phillippe, Karen Marlowe, Ruth Jeminiwa, Natalie Hohmann, Salisa Westrick, Amanda Fowler, Brent Fox
College of Pharmacy Faculty Papers
Background: Deep South states, particularly Alabama, experience disproportionately higher opioid prescribing rates versus national rates. Considering limited opioid use disorder (OUD) providers in this region, collaborative efforts between non-healthcare professionals is critical in mitigating overdose mortality. The Alabama Opioid Training Institute (OTI) was created in 2019 to empower community members to take action in combatting OUD in local regions. The OTI included: 1) eight full-day in-person conferences; and 2) an interactive mobile-enabled website ( https://alabamaoti.org ). This study assessed the impact of the OTI on influential community members' knowledge, abilities, concerns, readiness, and intended actions regarding OUD and opioid overdose ...
Patient Harm Associated With Illegal Online Sellers Of Covid- 19 Drug Products: A Year In Review,
2022
Butler University
Patient Harm Associated With Illegal Online Sellers Of Covid- 19 Drug Products: A Year In Review, Kyla Rae Maloney
Undergraduate Honors Thesis Collection
As the online marketplace continues to expand, more patients are turning to the internet for their needs, including COVID-19 pharmaceuticals. However, the current online marketplace is saturated with illegal sellers offering substandard and falsified (SF) products with the potential of causing harm to patients. The primary objective of this thesis is to identify documented cases of harm resulting from illegal online sale of SF COVID-19 related drug or vaccine products. This review utilizes reports by the Medicines Quality Monitoring Globe (MQM Globe) to assess patient harm associated with illegal online sales of COVID-19 marketed pharmaceuticals. This review found 28 references ...
Proposing An Educational Framework For Healthcare Professionals On The Topic Of Substandard Or Falsified Medications And Illegal Online Pharmacies,
2022
Butler University
Proposing An Educational Framework For Healthcare Professionals On The Topic Of Substandard Or Falsified Medications And Illegal Online Pharmacies, Margo Elaine Whitehead
Undergraduate Honors Thesis Collection
Background: Substandard or falsified medication prevalence in countries like the United States is documented with much more consistency than developing nations. On the contrary, although online pharmacies have been around for several decades, there is very limited data published establishing the prevalence of online pharmacy use by the general population (Fitler). Currently, there is no standardized curriculum regarding substandard or falsified medications and illegal online pharmacies offered to healthcare providers to combat the problems raised by counterfeits. Therefore, it is necessary to assess institutions’ current stance on implementing concepts in the curriculum and to create an educational framework based on ...
The Effect Of Covid-19 On Substance Use And Mental Health On A College Campus,
2022
Butler University
The Effect Of Covid-19 On Substance Use And Mental Health On A College Campus, Georgia Coffman
Undergraduate Honors Thesis Collection
In this research the authors surveyed a university population to determine the impact COVID-19 has had on substance use and mental health. Current research provides significant data indicating worsening mental health and substance use. This paper looks at how applicable those trends are to a small, private university in Indianapolis, Indiana. The data included 261 respondents composed of students, faculty, and staff of the university. The results reveal college students, faculty, and staff experienced statistically significant increases in feelings of unhappiness, depression, loneliness, hopelessness, agitation, and irritability during the pandemic compared to pre-pandemic. Data analysis of survey responses reveals COVID-19 ...
The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples,
2022
Chapman University
The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples, Qamar Alshammari
Pharmaceutical Sciences (PhD) Dissertations
The wavelength is used to identify the exact location and quantify the number of molecules in the spectral imaging system. It aids in identifying materials and studying their quantities by examining how they interact with light. A traditional spectrometer provides spectrum information of chemical compounds, while standard imaging provides the intensity at each pixel of the image. Spectral imaging (SI) combines these two aspects by equipping intensity and spectral data for each pixel. In biomedical research, it is important to assess the inorganics/organics molecules to understand drug activity, cellular toxicity, and distribution. Using the microscopy technique, we found for ...
The Impact Of The Covid-19 Pandemic On Antimicrobial Stewardship Practices And Their Effect On Veterinary Medicine,
2022
University of Maine - Main
The Impact Of The Covid-19 Pandemic On Antimicrobial Stewardship Practices And Their Effect On Veterinary Medicine, Erin N. Bradstreet
Honors College
Antimicrobials are essential in the treatment of diseases in both humans and animals, but antimicrobial resistance threatens their efficacy. As more microorganisms become resistant to an ever-growing list of antimicrobials, diseases that used to be simple to treat are becoming increasingly difficult to manage. The major factors contributing to antimicrobial resistance are overuse and misuse of antimicrobials. In order to combat the problem of resistance, antimicrobial stewardship programs that aim to improve antimicrobial prescribing and use practices are becoming increasingly widespread. These programs are quite common in human medicine, but the COVID-19 pandemic disrupted many aspects of life, including antimicrobial ...
Assessing Nutritional Health Knowledge In Sharing Clinic Patients With Diabetes,
2022
University of Nebraska Medical Center
Assessing Nutritional Health Knowledge In Sharing Clinic Patients With Diabetes, Minden Huntrods
Capstone Experience
Effective diabetes prevention and management relies on nutritional behaviors, thus a basic level of health knowledge is important for patients with diabetes and their caregivers in their quest to acquire acute glycemic control and minimize negative health outcomes (Ley et al., 2014). The purpose of this study was to assess the nutrition-related health knowledge of patients living with diabetes who are seen at the UNMC Sharing Clinic by use of a verbal questionnaire. This nutritional health knowledge assessment was a quantitative, prospective, survey-based study utilizing descriptive statistics. Approximately 86% of patients were proficient in food group and nutritious foods knowledge ...
The Impact Of Remote Optimization Of Guideline-Directed Medical Therapy In Patients With Nyha Stage Ii And Iii Heart Failure,
2022
Providence Medical Group
The Impact Of Remote Optimization Of Guideline-Directed Medical Therapy In Patients With Nyha Stage Ii And Iii Heart Failure, Maurice N. Tran, Christine Doran, Trevor Laursen, Kellie Graybosch, Jacob Abraham
Providence Pharmacy PGY2 Program at Providence Medical Group 2022
No abstract provided.
Dalbavancin Utilization And Associated Clinical Outcomes Within A Large, Integrated Health System,
2022
Providence Medical Group
Dalbavancin Utilization And Associated Clinical Outcomes Within A Large, Integrated Health System, Meagan Greckel, Brent Footer
Providence Pharmacy PGY2 Program at Providence Medical Group 2022
No abstract provided.
Standardized Pharmacist Led Medication Review In Patients With Recent Falls,
2022
Providence Medical Group
Standardized Pharmacist Led Medication Review In Patients With Recent Falls, Christopher Houpt, Natsuki Kubotera
Providence Pharmacy PGY2 Program at Providence Medical Group 2022
No abstract provided.
Protocol Analysis Of An Antimicrobial Renal Dose Protocol At A Large, Tertiary Medical Center,
2022
Providence
Protocol Analysis Of An Antimicrobial Renal Dose Protocol At A Large, Tertiary Medical Center, Nicole Hulsebus, Meagan Greckel, Brent Footer
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
Evaluation Of Infusion Reactions Associated With Intravenous Immune Globulin (Ivig) In Neonatal And Pediatric Patients,
2022
Providence
Evaluation Of Infusion Reactions Associated With Intravenous Immune Globulin (Ivig) In Neonatal And Pediatric Patients, Katie Couch, Samantha Tatz
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
Evaluation Of Pharmacist-Led Transitions Of Care (Toc) Discharge Pilot Program For Reducing 30-Day Readmission Rates In Patients With Chronic Obstructive Pulmonary Disease (Copd, Ann Tong, Hyesoo Chae, Addison Pang, Tony Lucchi
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
Tenecteplase Implementation For Ischemic Stroke At A Large Tertiary Medical Center,
2022
Providence
Tenecteplase Implementation For Ischemic Stroke At A Large Tertiary Medical Center, Laura Kays, Bryce Winn, Aimee Doyle
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
Prescribing Patterns Of Antipsychotics For Agitation Or Delirium Management In Non-Critically Ill Patients,
2022
Providence
Prescribing Patterns Of Antipsychotics For Agitation Or Delirium Management In Non-Critically Ill Patients, Emily Chang, Pamela Levine
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
An Evaluation Of Oral Anticoagulation Initiation After Ischemic Stroke In Patients With Atrial Fibrillation/Atrial Flutter At Hospital Discharge,
2022
Providence
An Evaluation Of Oral Anticoagulation Initiation After Ischemic Stroke In Patients With Atrial Fibrillation/Atrial Flutter At Hospital Discharge, Jessica Zhao, Meri Slavica, Vanessa Jenkins, Natalie Swearingen
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.