Development And Implementation Of An Evidence Based Practice Guideline Related To The Management Of Adult Angioedema,
2024
Otterbein University
Development And Implementation Of An Evidence Based Practice Guideline Related To The Management Of Adult Angioedema, Megan Przybysz
Doctor of Nursing Practice Scholarly Projects
Angioedema (AE) is a potentially life-threatening medical condition that occurs with a higher frequency than medical providers may expect, with the emergency department (ED) serving as the usual first point of medical contact for patients. Any hesitation in recognizing AE or inconsideration of the disease process in differential diagnoses may lead to a dangerous delay of care. Due to the potential rapid progression of airway obstruction in AE, inexperienced providers should not attempt intubation, instead deferring to providers experienced in alternative airway techniques (i.e., anesthesia providers). The primary goal of this project is to develop an evidencebased practice guideline for …
Raman Spectroscopic Analysis Of Human Serum Samples Of Convalescing Covid-19 Positive Patients,
2023
Technological University Dublin
Raman Spectroscopic Analysis Of Human Serum Samples Of Convalescing Covid-19 Positive Patients, Hugh Byrne, Naomi Jackson, Jaythoon Hassan
Articles
Rapid screening, detection and monitoring of viral infection is of critical importance, as exemplified by the rapid spread of SARS-CoV-2, leading to the worldwide pandemic of COVID-19. This is equally the case for the stages of patient convalescence as for the initial stages of infection, to understand the medium and long terms effects, as well as the efficacy of therapeutic interventions. Optical spectroscopic techniques potentially offer an alternative to currently employed techniques of screening for the presence, or the response to infection. In this study, the ability of Raman spectroscopy to distinguish between samples of the serum of convalescent COVID-19 …
Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance,
2023
California Polytechnic State University, San Luis Obispo
Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian
Biomedical Engineering: Graduate Reports and Projects
As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …
Abcb5+ Mesenchymal Stromal Cells Therapy Protects From Hypoxia By Restoring Ca2+ Homeostasis In Vitro And In Vivo,
2023
Edith Cowan University
Abcb5+ Mesenchymal Stromal Cells Therapy Protects From Hypoxia By Restoring Ca2+ Homeostasis In Vitro And In Vivo, Kaixuan Yan, Jiaxing Zheng, Mark Andreas Kluth, Lin Li, Christoph Ganss, Benito Yard, Richard Magdeburg, Markus H. Frank, Prama Pallavi, Michael Keese
Research outputs 2022 to 2026
Background:
Hypoxia in ischemic disease impairs Ca2+ homeostasis and may promote angiogenesis. The therapeutic efficacy of mesenchymal stromal cells (MSCs) in peripheral arterial occlusive disease is well established, yet its influence on cellular Ca2+ homeostasis remains to be elucidated. We addressed the influence of ATP-binding cassette subfamily B member 5 positive mesenchymal stromal cells (ABCB5+ MSCs) on Ca2+ homeostasis in hypoxic human umbilical vein endothelial cells (HUVECs) in vitro and in vivo.
Methods:
Hypoxia was induced in HUVECs by Cobalt (II) chloride (CoCl2) or Deferoxamine (DFO). Dynamic changes in the cytosolic- and endoplasmic reticulum …
Dentistry And The Law: Requiring Proof Of Adoption/Retaining Orthodontic Models,
2023
Kerr Webber
Dentistry And The Law: Requiring Proof Of Adoption/Retaining Orthodontic Models, Daniel Schulte Jd
The Journal of the Michigan Dental Association
In this Dentistry and the Law column, a dentist seeks guidance on handling a situation where racial differences between a child and an accompanying adult raised concerns during an examination, leading the dentist to request proof of adoption. The response clarifies that asking for proof of adoption is not illegal, citing relevant Michigan adoption statutes. The column advises adopting an office policy, emphasizing human trafficking training. Additionally, a dentist inquires about retaining orthodontic models and X-ray films. The answer recommends assuming orthodontic models are part of dental records, subject to a 10-year retention period. Patients can be given their models, …
An Investigation Of Match For Lossless Video Compression,
2023
University of Nebraska-Lincoln
An Investigation Of Match For Lossless Video Compression, Brittany Sullivan-Reicks
Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research
A new lossless video compression technique, Match, is investigated. Match uses the similarity between the frames of a video or the slices of medical images to find a prediction for the current pixel. A portion of the previous frame is searched to find a matching context, which is the pixels surrounding the current pixel, within some distance centered on the current location. The best distance to use for each dataset is found experimentally. The matching context refers to the neighborhood of w, nw, n, and ne, where the pixel in the previous frame with the closest matching context becomes the …
Conference Proceedings: Select Abstracts Presented At 2023 Advocate Aurora Scientific Day,
2023
Advocate Aurora Health
Conference Proceedings: Select Abstracts Presented At 2023 Advocate Aurora Scientific Day
Journal of Patient-Centered Research and Reviews
This abstract supplement includes findings presented at the 49th annual Advocate Aurora Scientific Day on May 24, 2023. The Scientific Day symposium provides a virtual forum for the sharing of preliminary results from research and case studies conducted by faculty, fellows, residents, and other health professionals associated with Illinois-based Advocate Health Care and Wisconsin-based Aurora Health Care.
Dietary Analysis For Hashimoto’S Thyroiditis: An Integrative Review,
2023
Kennesaw State University
Dietary Analysis For Hashimoto’S Thyroiditis: An Integrative Review, Evan Thompson, Alison Hultquist
Master of Science in Nursing Final Projects
Abstract
Hashimoto’s Thyroiditis (HT) is the leading cause of primary hypothyroidism in the United States. In HT, there is an infiltration by lymphocytes which leads to the production of autoantibodies against the thyroid gland. Throughout this integrative review, the aim was to evaluate the effectiveness of micronutrient supplementation and dietary management as adjunct treatments in HT. The purpose was to assist primary care providers in the development of a more holistic plan of care. Literature published within the past seven years was gathered and reviewed from PubMed, CINAHL, and Cochrane Library. Findings indicate that many patients with HT may benefit …
Chemical Modification And Evaluation Of Cells Towards Use As Delivery Tools,
2023
University of Massachusetts Amherst
Chemical Modification And Evaluation Of Cells Towards Use As Delivery Tools, Bishnu Prasad Joshi
Doctoral Dissertations
CHEMICAL MODIFICATION AND EVALUATION OF CELLS TOWARDS USE AS DELIVERY TOOLS
SEPTEMBER 2023
BISHNU PRASAD JOSHI
M.S., SRI SATHYA SAI INSTITUTE OF HIGHER LEARNING
Ph.D., UNIVERSITY OF MASSACHUSETTS AMHERST
Directed by: Professor Michelle E. Farkas
Endogenous cells are being studied for use in various applications, such as next generation therapeutics and drug delivery vehicles. This is on account of their biocompatibility, amenable distribution profiles, and in many instances, recruitment to and localization of diseased tissues. Multiple cell types have been employed, including macrophages, stem cells, red blood cells, and T cells. Most examples of cell-based delivery utilize phagocytosed entities as …
Mining High Impact Combinations Of Conditions From The Medical Expenditure Panel Survey,
2023
University of Massachusetts Amherst
Mining High Impact Combinations Of Conditions From The Medical Expenditure Panel Survey, Arjun Mohan
Masters Theses
The condition of multimorbidity — the presence of two or more medical conditions in an individual — is a growing phenomenon worldwide. In the United States, multimorbid patients represent more than a third of the population and the trend is steadily increasing in an already aging population. There is thus a pressing need to understand the patterns in which multimorbidity occurs, and to better understand the nature of the care that is required to be provided to such patients.
In this thesis, we use data from the Medical Expenditure Panel Survey (MEPS) from the years 2011 to 2015 to identify …
Implementation Of Standardized Patient Education To Improve Adherence With Colonoscopy For Colorectal Cancer Screening,
2023
University of Tennessee, Knoxville
Implementation Of Standardized Patient Education To Improve Adherence With Colonoscopy For Colorectal Cancer Screening, Melissa Leal Hearn, Melissa M. Hessock, Tara L. Hahn
Graduate Publications and Other Selected Works - Doctor of Nursing Practice (DNP)
BACKGROUND: Colorectal cancer (CRC) is the third leading cause of cancer deaths among men and women in the U.S. CRC is preventable and manageable when detected early. Approximately 30% of average-risk Americans are overdue for colonoscopy screening. Colonoscopy screenings can reduce death by 67%. Current evidence suggests CRC screening education improves screening uptake among men and women at average-risk age.
LOCAL PROBLEM: The setting of this practice improvement project was a private colorectal surgery practice in South Texas, serving primarily Hispanic/Latino and Caucasian patients. Cancellation rates before colonoscopy were 16.8%, and there was no standardized education for CRC …
Harmonization Of Multi-Site Diffusion Tensor Imaging Data For Cervical And Thoracic Spinal Cord At 1.5 T And 3 T Using Longitudinal Combat,
2023
Thomas Jefferson University
Harmonization Of Multi-Site Diffusion Tensor Imaging Data For Cervical And Thoracic Spinal Cord At 1.5 T And 3 T Using Longitudinal Combat, Devon M. Middleton, Yutong Li, Andrew Chen, Russell Shinohara, Joshua Fisher, Laura Krisa, Mark Elliot, Scott H. Faro, John H. Woo, Adam E. Flanders, Feroze B. Mohamed
Department of Radiology Faculty Papers
MRI scanner hardware, field strengths, and sequence parameters are major variables in diffusion studies of the spinal cord. Reliability between scanners is not well known, particularly for the thoracic cord. DTI data was collected for the entire cervical and thoracic spinal cord in thirty healthy adult subjects with different MR vendors and field strengths. DTI metrics were extracted and averaged for all slices within each vertebral level. Metrics were examined for variability and then harmonized using longitudinal ComBat (longComBat). Four scanners were used: Siemens 3 T Prisma, Siemens 1.5 T Avanto, Philips 3 T Ingenia, Philips 1.5 T Achieva. Average …
Decreasing Perioperative Medication Errors With Standardized Labeling Education,
2023
University of Tennessee, Knoxville
Decreasing Perioperative Medication Errors With Standardized Labeling Education, Stephanie Mccain, Emily Almond, Anna Wong, Julie Bonom
Graduate Publications and Other Selected Works - Doctor of Nursing Practice (DNP)
BACKGROUND: Medication errors are prevalent within the perioperative setting (Wahr et al., 2017). The anesthesia provider is the sole professional in charge of the medication process in the operating room, which results in fewer safety checks than in other healthcare settings (Nanji et al., 2016).
LOCAL PROBLEM: The proposed scholarly project aimed to reduce medication errors at an academic medical center in the Southeast using an educational module focused on standardized narcotic syringe labeling. The participants were anesthesia providers in the operating room at the project site.
METHODS: The Evidence-Based Practice Improvement model was used to guide the development, implementation, …
Botulinum Toxin Type A Injections For Refractory Abdominal Dystonia: A Case Report,
2023
University of Michigan
Botulinum Toxin Type A Injections For Refractory Abdominal Dystonia: A Case Report, William J. Naber Ii, Jodi M. Wilhelm, Kurt A. Kuhlman, Gabriel Howard
Graduate Medical Education Research Journal
Background: A 58-year-old male with chronic bilateral treatment resistant abdominal spasms secondary complications of ascites/ alcoholic cirrhosis. Spasms would occur 4-5 times/day, lasting minutes to hours despite a 2-year course of therapeutic and pharmacological interventions. Due to treatment refraction, 6 uniformly spaced botulinum toxin type A (BTX-A) injections were placed per side, using electromyography for audible intramuscular syringe placement confirmation, while visual confirmation was made via ultrasound. During the initial trial, 6 evenly spaced injections were performed bilaterally, uniformly distributing 80U/side. Injections began bilaterally just medial to the junction of the inferior rib cage border/ anterior axillary line and progressed …
Medication-Assisted Therapy And First Episode Psychosis: Evaluating Treatment And Readmission Rates: A Scoping Review,
2023
University of Tennessee Health Science Center
Medication-Assisted Therapy And First Episode Psychosis: Evaluating Treatment And Readmission Rates: A Scoping Review, Whitney Nichole Trotter Ms, Bsn, Rdn/Ldn, Rn, Margaret Carrie Harvey Phd, Aprn, Acnp-Bc, Chfn
Doctor of Nursing Practice Projects
Purpose/Background:
There is limited research aimed at addressing the reoccurrence of admission rates for first-episode psychosis. Research shows that early interventions for first-episode psychosis lead to remissions and prevention of relapses. Research also estimates that approximately one-half of first-episode clients have a history of cannabis abuse or dependence and one-third have a current cannabis use disorder (Wisdom et al., 2011). This study looks to determine whether Medication-assisted therapy (MAT) impacts readmission rates for patients who have substance use disorder and first-episode psychosis within six months of discharge.
Methods:
A comprehensive literature search was conducted using several electronic databases, including PubMed, …
Tachycardia Therapy Outcomes Of Ischemic Versus Nonischemic Cardiomyopathy On Cardiac Resynchronization Therapy: A Propensity Score-Matched Analysis,
2023
Department of electrophysiology, Armed Forces Institute of Cardiology/National Institute of Heart Disease, Rawalpindi, Pakistan
Tachycardia Therapy Outcomes Of Ischemic Versus Nonischemic Cardiomyopathy On Cardiac Resynchronization Therapy: A Propensity Score-Matched Analysis, Jahanzeb Malik, Muhammad Awais, Muhammad Shabbir, Amer Rauf, Shehzad Zaffar, Azmat Hayat, Amin Mehmoodi
Journal of Community Hospital Internal Medicine Perspectives
Objective This investigation aimed to investigate differences between dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) patients treated with cardiac resynchronization therapy with defibrillator (CRT-D) for tachycardia therapy-related outcomes as well as mortality during follow-up of at least 1 year. Methods Seventy-eight patients with DCM (n=42) and ICM (n=36) with implantation or upgradation to CRT-D were included in this study and analyzed for incidence of non-sustained ventricular tachycardia (NSVT), non-sustained ventricular fibrillation (NSVF), defibrillator therapies, anti-tachycardia pacing (ATP), and mortality. Results DCM was the underlying etiology in 42 (53.84%) and ICM in 36 (46.15%). Time to first therapy was numerically longer …
Smartphone-Based High-Performance Thin Layer Chromatographic Method Along With Benchtop Densitometry For Simultaneous Quantification Of Co-Formulated Dutasteride With Silodosin And Their Residuals On Manufacturing Equipment's Surfaces,
2023
Analytical Chemistry Department, Faculty of Pharmacy - Cairo University, Kasr El-Aini Street, ET-11562, Cairo - Egypt
Smartphone-Based High-Performance Thin Layer Chromatographic Method Along With Benchtop Densitometry For Simultaneous Quantification Of Co-Formulated Dutasteride With Silodosin And Their Residuals On Manufacturing Equipment's Surfaces, Mina Wadie, Ezzat M. Abdel-Moety, Mamdouh R. Rezk, Hoda M. Marzouk
Bulletin of Faculty of Pharmacy Cairo University
The significant advancement in smartphone digital cameras has expanded the possibilities for their usage as a portable, easily used detector in several analytical procedures. In this study, a unique and smart high-performance thin layer chromatographic (HPTLC) method based on a smartphone was presented for the simultaneous analysis of silodosin and dutasteride, two urological medications used to treat benign prostatic hyperplasia.First, environmentally friendly mobile phase was used to achieve chromatographic separation, and for repeatable findings, the produced plates were shot using the back camera of smartphone mounted atop a made-up twoillumination source chamber.
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients,
2023
Wayne State University
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients, Abigail C. Kuplicki
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Moriarty PM, Thompson PD, Cannon CP, et al. Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial. J. Clin. Lipidol. 2015;9(6):758-769. https://doi.org/10.1016/j.jacl.2015.08.006
for a statin-intolerant patient with hyperlipidemia.
Slow Surgical Correction Affects More Than Just The Bowels,
2023
Wayne State University School of Medicine
Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi
Clinical Research in Practice: The Journal of Team Hippocrates
Reflection on how delayed colostomy reversal affects a patient's mental and physical well-being.
Sarcopenic Obesity, Pathogenesis, And Treatment With A Focus On Exercise And Protein Intake,
2023
Izmir Katip Çelebi University, Faculty of Health Sciences, Department of Nutrition and Dietetic, Izmir, Turkey
Sarcopenic Obesity, Pathogenesis, And Treatment With A Focus On Exercise And Protein Intake, Yasemin Karaağaç
Journal of Mind and Medical Sciences
Sarcopenic obesity involves the co-occurrence of sarcopenia and obesity, yields more health risks than either condition alone, thus requiring prevention and treatment for healthy aging. In this review, the literature on the diagnosis of sarcopenic obesity, the mechanisms of its pathogenesis and treatment with emphasis on exercise and dietary protein were revised. Changes in body composition and sex hormones with age, myocellular mechanisms, inflammation, oxidative stress, physical inactivity, and insufficient protein intake are the main factors associated with the pathogenesis of sarcopenic obesity. Treatment targets weight loss while preserving muscle mass and function. Promising approaches involve high-protein and low-calorie diets …