Tracing The Twenty-Year Evolution Of Developing Ai For Eye Screening In Singapore: A Master Chronology Of Sidrp, Selena+ And Eyris,
2023
Singapore Management University
Tracing The Twenty-Year Evolution Of Developing Ai For Eye Screening In Singapore: A Master Chronology Of Sidrp, Selena+ And Eyris, Steven M. Miller
Research Collection School Of Computing and Information Systems
This working paper is entirely comprised of a timeline table that begins in 2002 and runs through mid-2023. Across these two decades, this timeline traces the evolutionary development of the following:
- The early Singapore R&D efforts to apply software-based image analysis algorithms and methods to analyse eye retina images for diabetic retinopathy and other eye diseases. This was based on a collaboration between the Singapore Eye Research Institute (SERI) and its parent organization, the Singapore National Eye Centre (SNEC), with faculty from the School of Computing at National University of Singapore.
- The establishment and operation of the Singapore Integrated Diabetic …
Comprehensive Analysis Of The Retinal Cell Contributions To The Human Erg,
2023
Smith-Kettlewell Institute
Comprehensive Analysis Of The Retinal Cell Contributions To The Human Erg, Christopher W. Tyler
MODVIS Workshop
Purpose. Standard electroretinogram (ERG) protocols are largely designed to isolate the responses of the rod and cone retinal pathways, including the use of adapting backgrounds to suppress unwanted off-pathway responses. Here, we record spectral ERGs in the low-to-high mesopic sensitivity range in the absence of any adapting background in order to assess interactions between the pathways.
Methods. We have developed a comprehensive neuroanalytic model of the component structure of the ERG driven by knowledge of the underlying retinal physiology, to enhance its power as a critical diagnostic tool for a broad range of both retinal and systemic dysfunctions. The ERG …
Design And Synthesis Of Peripherally Selective Endocannabinoid Enzyme Inhibitors For Ocular Indications,
2023
Liberty University
Design And Synthesis Of Peripherally Selective Endocannabinoid Enzyme Inhibitors For Ocular Indications, Kezia Reji Thomas
Senior Honors Theses
Peripherally selective compounds have been found to stimulate endocannabinoid receptor activity, which has been observed to have positive physiological effects such as ocular wound healing and inflammation control. The activation of the cannabinoid 1 receptor via binding of the endogenous ligands, anandamide and 2-arachidonoylglycerol, has been indicated to elicit these effects. Both ligands are controlled by two hydrolase enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), which can be targeted for therapeutic inhibition. Sulfonamide derivatives of JZL195 containing carbamate functionalities in the southern region of the inhibitor compounds were produced using novel carbamate exchange reactions. Polar functionalities were …
Book Review: The Paradox Of The Immune System: Protection, Chronic Inflammation, Autoimmune Disease, Cancer, And Pandemics,
2023
University of the Incarnate Word
Book Review: The Paradox Of The Immune System: Protection, Chronic Inflammation, Autoimmune Disease, Cancer, And Pandemics, Lourdes A. Fortepiani, Md, Phd
Optometric Clinical Practice
Book Review:
Pandemics, Artificial Intelligence, Optometrists, COVID-19, Immune System Diseases, inflammation
Limitations Of Telemedicine Vs. Face-To-Face Eye Examination In A Patient With New Headaches,
2023
Northport VAMC, Private Practice
Limitations Of Telemedicine Vs. Face-To-Face Eye Examination In A Patient With New Headaches, Joseph Hallak, Od, Danielle Kalberer, Od
Optometric Clinical Practice
Background: During the emergence and rise of COVID-19, precaution directives and limitations on in-person eye examinations re-routed a significant portion of care to telemedicine and virtual modalities. While these technologies allowed for healthcare communications that otherwise could not occur during such trying times, there are major limitations to these sanctioned applications. This report will present a seemingly benign case that could have easily been re-routed from an in-person examination to a telemedicine version due to the patient’s seemingly “routine” vision complaints.
Case Report: A 50-year-old male patient contacted the eye clinic with a complaint of a minor, new, unexplained headache …
Lyme Disease Neuroretinitis: A Case Report And Review Of Immunologic Workup,
2023
Veterans Administration Texas Valley Coastal Bend Health Care System
Lyme Disease Neuroretinitis: A Case Report And Review Of Immunologic Workup, Michael Wingard, Od, Jeffery Curry, Od, Jeffrey L. Weaver, Od, Ms
Optometric Clinical Practice
Background: Lyme disease is an infection caused by a bacterial spirochete of the borrelia genus. The human vector is from a tick bite by an infected tick of the ixodes genus, commonly referred to as the deer tick or black legged tick. The incidence of Lyme disease is increasing in the United States. Once infected, Lyme disease manifestations usually depend on the stage of infection with late stage infection often causing debilitating illness.1
Case Report: Neuroborreliosis refers to borrelia, causing neurological infection and can occur as acute or late manifestation of Lyme disease. Neuroretinitis is a rare …
Ocular Manifestations Of Septo-Optic Dysplasia,
2023
North Florida/South Georgia Veterans Health System
Ocular Manifestations Of Septo-Optic Dysplasia, Rena Cappelli, Od, Tiffany Tucker Christiansen, Od, Danielle Vance Taylor, Od
Optometric Clinical Practice
Background: Septo-optic dysplasia (SOD) is a congenital deformity of the brain which can result in neurologic, systemic, and physical malformation.Due to the proximity of these deformities to the optic chiasm and optic nerves, ocular manifestations are common.
Case Report: A 28-year-old male with a long-standing history of reduced vision presented for a routine eye examination. Upon examination he was found to have an afferent pupillary defect, bilateral optic nerve pallor with corresponding nerve fiber layer thinning by optical coherence tomography. Humphrey visual field testing revealed a bi-temporal visual field defect. Neurological imaging was obtained with a subsequent diagnosis …
Multimodal Imaging Reveals Bilateral Idiopathic Multiple Retinal Pigment Epithelial Detachments: A Case Report,
2023
University of the Incarnate Word
Multimodal Imaging Reveals Bilateral Idiopathic Multiple Retinal Pigment Epithelial Detachments: A Case Report, Diana H. Ho, Od, Joseph J. Pizzimenti, Od, Patricia C. Sanchez-Diaz, Dvm, Phd, Stephanie Schmiedecke-Barbieri, Od, Alexandra Zuercher, Od
Optometric Clinical Practice
Background: Retinal pigment epithelial detachment (RPED) is a nonspecific finding that is common in several ocular diseases; however, cases of bilateral idiopathic multiple RPEDs are rare. Less than 50 cases have been reported to date. Bilateral multiple RPEDs are usually idiopathic and benign in nature but can infrequently be associated with various ocular and systemic diseases, including central serous chorioretinopathy (CSC). The potential role of genetic factors in this condition remains elusive. We present a case where multimodal imaging assisted in revealing the diagnosis as well as discuss the potential implications of some of the genetic findings for this …
Acute Syphilitic Posterior Placoid Chorioretinitis; A Case Report And Review,
2023
Minneapolis VA Health Care System
Acute Syphilitic Posterior Placoid Chorioretinitis; A Case Report And Review, Kristin Wilson, Od, Amy Garbo Maxey, Od
Optometric Clinical Practice
Background: Acute syphilitic posterior placoid chorioretinopathy (ASPPC) is a rare but defining characteristic of ocular syphilis. Clinical findings are subtle, geographic, yellowish, macular lesions, affecting the outer-retina and inner choroid, and often associated with subretinal fluid in the early phase. This case report will review the clinical signs of ASPPC to aid the practitioner in identification and recognition of its clinical importance as it relates to early diagnosis, treatment and prognosis.
Case Report: A 79-year-old African American male presented to clinic with a chief complaint of blur in the right eye for the past two days. Spectral Domain Optical Coherence …
Optic Disc Drusen Resulting In Disqualifying Field Loss,
2023
Department of Veterans Affairs, Northern Indiana Healtcare System
Optic Disc Drusen Resulting In Disqualifying Field Loss, Robert C. Binkley, Od
Optometric Clinical Practice
Background: Optic nerve (or disc) drusen is the presence of hyaline bodies at the optic nerve head. The drusen may be visible upon funduscopic examination or may present as buried. Timely diagnosis and responsible imaging may help inform the patient of the potential for future concerns. The long-term prognosis is good for most patients, however, they may experience progressive peripheral vision loss that may reduce the patient’s quality of life. Neuroprotective options have previously been discussed with minimal clinical effectiveness, however, new medications may aid in future treatment.
Case Report: A patient presenting with mild and slowly progressing vision loss …
You Can Lead A Horse To Water,
2023
University of the Incarnate Word
You Can Lead A Horse To Water, Paul B. Freeman, Od
Optometric Clinical Practice
Letter from the Editor
Barriers To Screening For Diabetic Retinopathy: A Scoping Review,
2023
University of Tennessee Health Science Center
Barriers To Screening For Diabetic Retinopathy: A Scoping Review, Amy Cooper Rn, Bsn, Lajerica Bates Rn, Bsn, Julie Bridges Rn, Bsn, Laura Reed Dnp, Fnp-Bc
Doctor of Nursing Practice Projects
Purpose/Background
More than 34 million people in the United States have diabetes. Diabetic retinopathy (DR) is a major complication of diabetes and a leading cause of vision loss. Risk factors for diabetic retinopathy include Type 1 and Type 2 Diabetes, hypertension, smoking, and being African American or Hispanic/Latino. This scoping review seeks to analyze the current research on ways to increase vision screenings, thus reducing cases of diabetic retinopathy in adults.
Methods
Between September 2020 and November 2021, a search was conducted using PubMed, EBSCOhost, Medline, and CINAHL to identify articles using keywords such as diabetic retinopathy and ophthalmology. This …
When Mental Health Becomes Physical,
2023
Ouachita Baptist University
When Mental Health Becomes Physical, Piper Fain
Honors Theses
Glaucoma, the presence of elevated intraocular pressure, has been shown to directly correlate to elevated blood pressure levels. Likewise, numerous studies have been conducted on the relationship between elevated blood pressure and anxiety in individuals suffering from both. One might wonder, then, if there is any correlation between glaucoma and anxiety? My thesis expands upon this question utilizing a survey distributed to patients at local optometry clinics.
Comparación De Las Manifestaciones Oculares Durante El Contagio Por Covid-19 Y Después De La Vacunación,
2023
Universidad El Bosque
Comparación De Las Manifestaciones Oculares Durante El Contagio Por Covid-19 Y Después De La Vacunación, Luisa Fernanda Aguilar Serrano, Daniel Sebastián Cruz Mendoza, Nicolle Daniela Hernández Pacheco, Diana Valeria Rey-Rodríguez, Laura Nathaly Rojas Sánchez
Ciencia y Tecnología para la Salud Visual y Ocular
El objetivo del presente estudio es identificar la frecuencia de manifestaciones sistémicas y oculares en pacientes diagnosticados con COVID-19, y analizar los síntomas asociados a la vacunación. Como metodología, se diseñó un cuestionario de 15 preguntas sobre manifestaciones oculares asociadas a la SARS-CoV-2 y síntomas tras la vacunación. Se realizó un análisis descriptivo, incluyendo el uso de porcentajes y frecuencias para variables cualitativas. Se realizaron análisis bivariados según la relación existentes entre las variables de interés. En el estudio participaron 270 personas en los siguientes porcentajes según edad: menores de 18 años, 10,7 % (29 personas); de 18 a 30 …
Efecto Del Humo De Tabaco En La Película Lagrimal En Fumadores Activos Y Pasivos: Revisión De Tema,
2023
Universidad Nacional Autónoma de México
Efecto Del Humo De Tabaco En La Película Lagrimal En Fumadores Activos Y Pasivos: Revisión De Tema, Mayra Jessica Tapia-Vargas, Mitzi Lorea Rodríguez De La Torre, Aranza Valeria García-Figueroa, Amabile A. Velo-Silvestre
Ciencia y Tecnología para la Salud Visual y Ocular
Fumar tabaco de modo habitual, así como estar expuesto prolongadamente al humo del tabaco, son factores de riesgo para el desarrollo de diversos problemas en la superficie ocular; entre ellos, las alteraciones en la lágrima. El objetivo de esta revisión de tema es sintetizar la evidencia disponible sobre los diversos cambios que puede presentar la película lagrimal por la exposición del humo de tabaco. Para ello, se incluyeron estudios clínicos publicados entre los años 2016 y 2021, La búsqueda se realizó en tres bases de datos: PubMed, Web of Science y Science Direct, mediante las siguientes palabras clave: “tear film” …
The Association Between Time Spent On Screens And Reading With Myopia, Premyopia And Ocular Biometric And Anthropometric Measures In 6- To 7-Year-Old Schoolchildren In Ireland,
2023
Technological University Dublin
The Association Between Time Spent On Screens And Reading With Myopia, Premyopia And Ocular Biometric And Anthropometric Measures In 6- To 7-Year-Old Schoolchildren In Ireland, Síofra Harrington, Veronica O'Dwyer
Articles
Purpose More time spent on near tasks has consistently been associated with the promotion of myopia. The World Health Organization advises limiting daily screentime to less than 2 h for children aged five and over. This study explored the relationship between time spent on screens and reading/writing with refractive status, ocular biometric and anthropometric factors in 6-to 7-year- olds in Ireland.
Methods Participants were 723 schoolchildren (377 boys [51.8%]), mean age 7.08 (0.45) years. The examination included cycloplegic autorefraction (1% cyclopentolate hydrochloride), ocular biometry (Zeiss IOLMaster), height (cm) and weight (kg). Screentime and reading/writing time were reported by parents/legal guardians …
Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells,
2023
Noorda College of Osteopathic Medicine
Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Comparison Of Cycloplegia At 20- And 30-Minutes Following Proxymetacaine And Cyclopentolate Instillation In White 12-13-Year-Olds,
2023
Technological University Dublin, Centre for Eye Research Ireland
Comparison Of Cycloplegia At 20- And 30-Minutes Following Proxymetacaine And Cyclopentolate Instillation In White 12-13-Year-Olds, Megan Doyle, Veronica O'Dwyer, Siofra Harrington
Articles
Clinical Relevance
Reducing the time between drop instillation and refraction reduces the time paediatric patients and young adults spend in practice, facilitating more eye examinations daily.
Background
The current procedure for paediatric cycloplegic refraction is to wait for at least 30-minutes post-instillation of a cycloplegic before measuring spherical equivalent refraction. This study compared cycloplegia at 20- and 30-minutes following 0.5% proxymetacaine and 1.0% cyclopentolate in 12-13-year-olds.
Methods
Participants were 99 white 12-13-year-olds. One drop of proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) followed by one drop of cyclopentolate hydrochloride (Minims, 1.0% w/v, Bausch & Lomb, UK) was instilled …
Prescribing Patterns Of Myopia Control Contact Lenses Among Optometrists In Ireland,
2023
Technological University Dublin
Prescribing Patterns Of Myopia Control Contact Lenses Among Optometrists In Ireland, Michael Moore, Daniel Ian Flitcroft, James Loughman
Articles
Purpose
This retrospective analysis of electronic medical record (EMR) data investigated the prescribing patterns of soft myopia control contact lens (MCCL) treatments since their introduction in Ireland in 2017.
Methods
Anonymised EMR data were sourced from 33 optometry practices in Ireland from 2017 to 2021 to determine the number of practices prescribing MCCLs to myopic children 5–18 years old. In MCCL-prescribing practices, the proportion of contact lens wearing children fitted with MCCLs and the proportion of progressive (≤−0.25 D/year) myopic children fitted with MCCLs were determined. Logistic regression was used to determine which factors influenced the likelihood of being prescribed …
Importance Of Eye Exams As A Secondary Preventative Measure For Diabetic Retinopathy: Winning The War On Blindness,
2023
Bethel University
Importance Of Eye Exams As A Secondary Preventative Measure For Diabetic Retinopathy: Winning The War On Blindness, Alondra S. Arredondo, Olivia Demeyer, Rachel Louise Pfenning-Wendt, Samuel Wolfe
All Electronic Theses and Dissertations
Despite current efforts by medical professionals to reduce the prevalence of diabetic retinopathy (DR), a microvascular complication of uncontrolled diabetes, this noncommunicable disease remains the leading cause of preventable vision loss worldwide (Cheloni et al., 2019). Research estimates 90% of DR cases could be prevented if detected early through routine eye exams, yet certain social determinants of health still remain a significant barrier for many individuals to receive this care. According to Wong & Sabanayagam (2020), only 25% of DM patients in developing countries receive routine care with adequate eye screenings. The goal of this community service project was to …
