Albany State University, Georgia
James Madison University
Morehead State University
University of New Hampshire, Durham
HCA Healthcare
University of Pennsylvania
Universidad de La Salle, Bogotá
University of North Florida
The University of Akron
How Does Apolipoprotein E Genotype Influence The Relationship Between Physical Activity And Alzheimer’S Disease Risk? A Novel Integrative Model,
2023
Edith Cowan University
How Does Apolipoprotein E Genotype Influence The Relationship Between Physical Activity And Alzheimer’S Disease Risk? A Novel Integrative Model, Jaisalmer De Frutos Lucas, Kelsey R. Sewell, Alejandra García-Colomo, Shaun Markovic, Kirk I. Erickson, Belinda M. Brown
Research outputs 2022 to 2026
Background:
Wide evidence suggests that physical activity (PA) confers protection against Alzheimer’s disease (AD). On the other hand, the apolipoprotein E gene (APOE) ε4 allele represents the greatest genetic risk factor for developing AD. Extensive research has been conducted to determine whether frequent PA can mitigate the increased AD risk associated with APOE ε4. However, thus far, these attempts have produced inconclusive results. In this context, one possible explanation could be that the influence of the combined effect of PA and APOE ε4 carriage might be dependent on the specific outcome measure utilised.
Main body:
In …
Longitudinal Association Of Remnant Cholesterol With Joint Arteriosclerosis And Atherosclerosis Progression Beyond Ldl Cholesterol,
2023
Edith Cowan University
Longitudinal Association Of Remnant Cholesterol With Joint Arteriosclerosis And Atherosclerosis Progression Beyond Ldl Cholesterol, Zhiyuan Wu, Jinqi Wang, Haiping Zhang, Huiying Pan, Zhiwei Li, Yue Liu, Xinlei Miao, Ze Han, Xiaoping Kang, Xia Li, Xiuhua Guo, Lixin Tao, Wei Wang
Research outputs 2022 to 2026
Background: Arteriosclerosis and atherosclerosis are closely related with cardiovascular disease (CVD) risk. Remnant cholesterol (RC) could predict CVD. However, its effect on joint arteriosclerosis and atherosclerosis progression remains unclear. This study aims to evaluate the association of RC with joint arteriosclerosis and atherosclerosis progression trajectories in the general population. Methods: This study collected data across five biennial surveys of the Beijing Health Management Cohort from 2010 to 2019. Multi-trajectory model was used to determine the joint arteriosclerosis and atherosclerosis progression patterns by brachial-ankle pulse wave velocity (baPWV) and ankle brachial index (ABI). We also performed discordance analyses for RC vs. …
Genetic Influences On The Response To Neuromodulation In Craving Behaviors,
2023
University of South Dakota
Genetic Influences On The Response To Neuromodulation In Craving Behaviors, Carly J. Haring
Honors Thesis
Obesity and eating disorders are highly prevalent in the United States. People who suffer from obesity and/or eating disorders face serious health consequences and even death. Current treatments are not effective as recovery rates are low, so there is a dire need for an effective treatment for obesity and eating disorders. There have been studies investigating the use of transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) of the dorsolateral prefrontal cortex (DLPFC) as a means of treatment for these people. While findings show promise, there is much variability. The goal of this study is to further prior …
Multiparametric Magnetic Resonance Imaging Artificial Intelligence Pipeline For Oropharyngeal Cancer Radiotherapy Treatment Guidance,
2023
The Texas Medical Center Library
Multiparametric Magnetic Resonance Imaging Artificial Intelligence Pipeline For Oropharyngeal Cancer Radiotherapy Treatment Guidance, Kareem Wahid
The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Dissertations and Theses (Open Access)
Oropharyngeal cancer (OPC) is a widespread disease and one of the few domestic cancers that is rising in incidence. Radiographic images are crucial for assessment of OPC and aid in radiotherapy (RT) treatment. However, RT planning with conventional imaging approaches requires operator-dependent tumor segmentation, which is the primary source of treatment error. Further, OPC expresses differential tumor/node mid-RT response (rapid response) rates, resulting in significant differences between planned and delivered RT dose. Finally, clinical outcomes for OPC patients can also be variable, which warrants the investigation of prognostic models. Multiparametric MRI (mpMRI) techniques that incorporate simultaneous anatomical and functional information …
Prevention Of Obesity-Related Morbidity & Mortality In Adults,
2023
Otterbein University
Prevention Of Obesity-Related Morbidity & Mortality In Adults, Rachelle Virgin
Masters Theses/Capstone Projects
Poster presentation on the prevention of obesity related morbidity and mortality in adults.
Hepatitis Screening,
2023
Otterbein University
Hepatitis Screening, Kathryn Bland
Masters Theses/Capstone Projects
Project on hepatitis screening.
The Effect Of Masks On Allergic Rhinitis Symptoms Related To Ragweed And Its Influence On College Students,
2023
Olivet Nazarene University
The Effect Of Masks On Allergic Rhinitis Symptoms Related To Ragweed And Its Influence On College Students, Katherine Knutte
Scholar Week 2016 - present
BACKGROUND: This study explored the effect of masks on allergic rhinitis related to ragweed. Research has been shown that surgical and KN95 masks reduce allergic symptoms due to dust, pollen, and ragweed. A study in Israel found a strong correlation was between wearing a KN95 and reducing severe allergic rhinitis symptoms related to nasal symptoms and another study focusing on pollen supported this finding. Lastly, a previous study on ragweed found that all nasal symptoms improved, and ocular symptoms remained unchanged.
METHODS: This was a qualitative study involving twenty college students aged 18 to 25 from Olivet Nazarene …
Interactive Dashboard Of Diabetes In The Us,
2023
Southern Adventist University
Interactive Dashboard Of Diabetes In The Us, Marc Butler
Campus Research Day
The contribution of this research project is the construction and interactive dashboard in order to facilitate the visualization of diabetes-related data to the public
The Effects Of Creatine Supplementation On Muscle Synthesis And Fitness Levels In Drosophila Melanogaster Using A Model Of Muscle Atrophy,
2023
Olivet Nazarene University
The Effects Of Creatine Supplementation On Muscle Synthesis And Fitness Levels In Drosophila Melanogaster Using A Model Of Muscle Atrophy, Kevin Williams
Scholar Week 2016 - present
This study examines whether an inhibited electron transport chain can be aided with supplemented creatine to make up for the challenged adenosine triphosphate (ATP) production mechanism. The differences between male and female flies and the supplementation of creatine at a 0.15% concentration was studied. The relationship between these components was studied over the course of two 3-week trials using a fly treadmill and Drosophila. The effects of creatine on a mitochondrial disease modeled Drosophila melanogaster were analyzed by tracking climbing speed, leg width, and body width. The research yielded largely minimal differences between supplemented and non-supplemented, mutated, and non-mutated …
Prevention And Delayed Progression Of Diabetic Nephropathy,
2023
Southern Illinois University School of Medicine, Doctor of Medical Science
Prevention And Delayed Progression Of Diabetic Nephropathy, Russell Scott
SIU Journal of Medical Science Scholarly Works
ABSTRACT
Aim/Purpose: The purpose of this clinical research article is to determine if there are comparable alternatives to industry-standard or gold-standard renin-angiotensin system (RAS) blockade for diabetic nephropathy (DN) prevention or delayed progression when RAS blocking agents are contraindicated or not tolerated.
Method: A PubMed literature search was conducted utilizing search terms including diabetic nephropathy unaccompanied and in combination with sodium-glucose co-transporter 2 (SGLT2) inhibitor, glucagon-like peptide 1 (GLP1) receptor agonist, calcium channel blocker (CCB), mineralocorticoid receptor antagonist (MRA) and RAS blockade or blocker. PubMed search filters included full-text articles and article submissions no greater than 5 years from approximately …
Institute Of Cardiovascular Science And Medicine Faculty Of Medicine The University Of Hong Kong,
2023
Hong Kong College of Cardiology
Institute Of Cardiovascular Science And Medicine Faculty Of Medicine The University Of Hong Kong
Journal of the Hong Kong College of Cardiology
No abstract provided.
Abstracts For Lectures,
2023
Hong Kong College of Cardiology
Abstracts For Lectures
Journal of the Hong Kong College of Cardiology
No abstract provided.
9th Asian Preventive Cardiology And Cardiac Rehabilitation Conference Symposia,
2023
Hong Kong College of Cardiology
9th Asian Preventive Cardiology And Cardiac Rehabilitation Conference Symposia
Journal of the Hong Kong College of Cardiology
No abstract provided.
9th Asian Preventive Cardiology And Cardiac Rehabilitation Conference,
2023
Hong Kong College of Cardiology
9th Asian Preventive Cardiology And Cardiac Rehabilitation Conference
Journal of the Hong Kong College of Cardiology
No abstract provided.
Delivery Of The Immune System: Understanding The Development Of The Human Immune System Based On Birth Mode,
2023
Arcadia University
Delivery Of The Immune System: Understanding The Development Of The Human Immune System Based On Birth Mode, Sara Abbas
Faculty Curated Undergraduate Works
The creation of the immune system starts from the womb. The expecting mother plays an immense role outside of the genetic influence in developing a neonate’s immune system. The mode of birth has a substantial impact, as the neonate’s initial moments can have lasting impacts on the making of a proper immune system. A mother should have the choice in choosing between a vaginal birth or a cesarean section and this paper looks to provide aid in the decision process by contrasting the two modes in terms of immunological impact, especially as the rate of c-sections climb (1,2). The approach …
Improving Diabetes Management For School Health Workers Using A Live, Virtual Training Course,
2023
Baylor College of Medicine/Texas Children's Hospital
Improving Diabetes Management For School Health Workers Using A Live, Virtual Training Course, Bonnie Mccann-Crosby, Lisa Setchfield, Yvonne Barham, Dawn Espinosa, Jennifer Bailey, Beth Pali, Amanda Garey, Sarah Lyons, Rona Sonabend
Journal of Nursing & Interprofessional Leadership in Quality & Safety
Background: Type 1 diabetes is one of the most common chronic diseases in childhood. Optimal school nurse and staff education is critical to creating a safe learning environment and influencing long term outcomes of students with type 1 diabetes. The purpose of this project was to develop a virtual continuing education diabetes management course for school health workers to improve their knowledge of diabetes management and evaluate the effectiveness of the learning platform.
Methods: A total of 199 participants completed the live, virtual continuing education course. Participants completed a pre and post-test to assess improvements in the key learning objectives …
Efecto Del Humo De Tabaco En La Película Lagrimal En Fumadores Activos Y Pasivos: Revisión De Tema,
2023
Universidad Nacional Autónoma de México
Efecto Del Humo De Tabaco En La Película Lagrimal En Fumadores Activos Y Pasivos: Revisión De Tema, Mayra Jessica Tapia-Vargas, Mitzi Lorea Rodríguez De La Torre, Aranza Valeria García-Figueroa, Amabile A. Velo-Silvestre
Ciencia y Tecnología para la Salud Visual y Ocular
Fumar tabaco de modo habitual, así como estar expuesto prolongadamente al humo del tabaco, son factores de riesgo para el desarrollo de diversos problemas en la superficie ocular; entre ellos, las alteraciones en la lágrima. El objetivo de esta revisión de tema es sintetizar la evidencia disponible sobre los diversos cambios que puede presentar la película lagrimal por la exposición del humo de tabaco. Para ello, se incluyeron estudios clínicos publicados entre los años 2016 y 2021, La búsqueda se realizó en tres bases de datos: PubMed, Web of Science y Science Direct, mediante las siguientes palabras clave: “tear film” …
Comparación De Las Manifestaciones Oculares Durante El Contagio Por Covid-19 Y Después De La Vacunación,
2023
Universidad El Bosque
Comparación De Las Manifestaciones Oculares Durante El Contagio Por Covid-19 Y Después De La Vacunación, Luisa Fernanda Aguilar Serrano, Daniel Sebastián Cruz Mendoza, Nicolle Daniela Hernández Pacheco, Diana Valeria Rey-Rodríguez, Laura Nathaly Rojas Sánchez
Ciencia y Tecnología para la Salud Visual y Ocular
El objetivo del presente estudio es identificar la frecuencia de manifestaciones sistémicas y oculares en pacientes diagnosticados con COVID-19, y analizar los síntomas asociados a la vacunación. Como metodología, se diseñó un cuestionario de 15 preguntas sobre manifestaciones oculares asociadas a la SARS-CoV-2 y síntomas tras la vacunación. Se realizó un análisis descriptivo, incluyendo el uso de porcentajes y frecuencias para variables cualitativas. Se realizaron análisis bivariados según la relación existentes entre las variables de interés. En el estudio participaron 270 personas en los siguientes porcentajes según edad: menores de 18 años, 10,7 % (29 personas); de 18 a 30 …
Nutritional Management: Head And Neck Cancer,
2023
Otterbein University
Nutritional Management: Head And Neck Cancer, Christina Eagle
Masters Theses/Capstone Projects
Nutritional management in head and neck cancer patients will help to promote treatment compliance and reduction of treatment-related co-morbidities.
The Effects Of A Blood–Brain Barrier Penetrating Erythropoietin In A Mouse Model Of Tauopathy,
2023
Keck Graduate Institute
The Effects Of A Blood–Brain Barrier Penetrating Erythropoietin In A Mouse Model Of Tauopathy, Joshua Yang, Weijun Ou, Nataraj Jagadeesan, Juste Simanauskaite, Jiahong Sun, Demi M. Castellanos, David H. Cribbs, Rachita K. Sumbria
Pharmacy Faculty Articles and Research
Erythropoietin (EPO), a hematopoietic neurotrophin, is a potential therapeutic for Alzheimer’s disease (AD) but has limited blood–brain barrier (BBB) permeability. EPO fused to a chimeric transferrin receptor monoclonal antibody (cTfRMAb) enters the brain via TfR-mediated transcytosis across the BBB. We previously showed that cTfRMAb-EPO is protective in a mouse model of amyloidosis, but its effects on tauopathy are not known. Given that amyloid and tau pathology are characteristics of AD, the effects of cTfRMAb-EPO were studied in a tauopathy mouse model (PS19). Six-month-old PS19 mice were injected intraperitoneally with either saline (PS19-Saline; n = 9) or cTfRMAb-EPO (PS19-cTfRMAb-EPO, 10 mg/kg; …
