Electroporation-Mediated Delivery Of A Naked Dna Plasmid Expressing Vegf To The Porcine Heart Enhances Protein Expression,
2010
Old Dominion University
Electroporation-Mediated Delivery Of A Naked Dna Plasmid Expressing Vegf To The Porcine Heart Enhances Protein Expression, W. G. Marshall Jr., B. A. Boone, J. D. Burgos, S. I. Gografe, M. K. Baldwin, M. L. Danielson, M. J. Larson, D. R. Caretto, Y. Cruz, B. Ferraro, L. C. Heller, K. E. Ugen, M. J. Jaroszeski, R. Heller
Bioelectrics Publications
Gene therapy is an attractive method for the treatment of cardiovascular disease. However, using current strategies, induction of gene expression at therapeutic levels is often inefficient. In this study, we show a novel electroporation (EP) method to enhance the delivery of a plasmid expressing an angiogenic growth factor (vascular endothelial growth factor, VEGF), which is a molecule previously documented to stimulate revascularization in coronary artery disease. DNA expression plasmids were delivered in vivo to the porcine heart with or without coadministered EP to determine the potential effect of electrically mediated delivery. The results showed that plasmid delivery through EP significantly …
Isolation And Molecular Characterization Of Mycobacterium Avium Subsp. Paratuberculosis In Ireland,
2010
Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland.
Isolation And Molecular Characterization Of Mycobacterium Avium Subsp. Paratuberculosis In Ireland, Pierre Emmanuel Douarre
Theses
MAP is a proven animal pathogen causing Johne's disease, one of the most widespread and economically important diseases of ruminants. Since 1992 and the opening of the European market, the prevalence of MAP in Ireland has increased considerably. Improvements in diagnostic strategies for Ireland and elsewhere are urgently required. MAP infects a wide host range and has emerged as a potential threat to human health and has been associated with Crohn's disease. The control of paratuberculosis infection requires a better understanding of the genetic diversity of the pathogen. The objective of this study was to isolate and characterize this enteric …
Untreated And Enzyme-Modified Bovine Whey Products Reduce Association Of Salmonella Typhimurium, Escherichia Coli O157:H7 And Cronobacter Malonaticus (Formerly Enterobacter Sakazakii) To Caco-2 Cells,
2010
Technological University Dublin
Untreated And Enzyme-Modified Bovine Whey Products Reduce Association Of Salmonella Typhimurium, Escherichia Coli O157:H7 And Cronobacter Malonaticus (Formerly Enterobacter Sakazakii) To Caco-2 Cells, Rachel Halpin, D.B. Brady, E.D. O’Riordan, M. O’Sullivan
Articles
Adhesion of a micro-organism to a cell surface is often considered to be the first step in pathogenesis. Inhibiting this process may have therapeutic effects in vivo. This study investigates the inhibitory effects of various bovine whey products on the association of Salm. Typhimurium, E. coli O157:H7 and C. malonaticus (formerly Enterobacter sakazakii) to the human CaCo-2 cell line. Invasion of CaCo-2 cells by Salm. Typhimurium and C. malonaticus was also examined.
Understanding Stem Cell Research: Controversy And Promise,
2009
Providence College
Understanding Stem Cell Research: Controversy And Promise, Father Nicanor Austriaco
Rev. Nicanor Austriaco, O.P.
What are embryonic stem cells, why are they so exciting and yet controversial, and what can be done to move our society beyond the current moral and political impasse? To provide answers to these questions, we will begin with a basic introduction to the science behind stem cell research. We will then move to a description of the emerging field of regenerative medicine, the main reason why stem cell research has generated so much excitement in the scientific community. As we will see, the drive to develop stem cells for regenerative medicine has linked stem cell research with the controversy …
Polyphyly Of The Pikeminnows (Teleostei: Cyprinidae) Inferred Using Mitochondrial Dna Sequences,
2009
Utah Valley University
Polyphyly Of The Pikeminnows (Teleostei: Cyprinidae) Inferred Using Mitochondrial Dna Sequences, T. Heath Ogden
T. Heath Ogden
The phylogenetic relationships of the Colorado pikeminnow Ptychocheilus lucius, northern pikeminnow P. oregonensis, Sacramento pikeminnow P. grandis, Umpqua pikeminnow P. umpquae, and hardhead Mylopharodon conocephalus were examined by using molecular data to investigate monophyly of the genus Ptychocheilus. Phylogenies generated using DNA sequence data from the cytochrome b and 16S ribosomal DNA genes of the mitochondrial genome reveal that Ptychocheilus is a polyphyletic genus and suggest that the taxonomy of the group is in need of further revision. These data yield insights into the evolution of the pikeminnows and help place the significant evolutionary events in context with the geological …
“El Derecho De La Ue Relativo A Los Organismos Modificados Genéticamente: La Comisión Europea Cambia De Estrategia Para Permitir, Restringir O Prohibir Su Cultivo”,
2009
Asociación Iberoamericana para el Dereho Alimentario
“El Derecho De La Ue Relativo A Los Organismos Modificados Genéticamente: La Comisión Europea Cambia De Estrategia Para Permitir, Restringir O Prohibir Su Cultivo”, Luis González Vaqué
Luis González Vaqué
No abstract provided.
Vertical Dispersal Of Aedes (Stegomyia) Spp. In High-Rise Apartments In Putrajaya, Malaysia,
2009
Institute of Biological Sciences, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Vertical Dispersal Of Aedes (Stegomyia) Spp. In High-Rise Apartments In Putrajaya, Malaysia, Mohd Sofian Bin Azirun
Mohd Sofian Bin Azirun
A preliminary study on the vertical dispersal of Aedes populations in high-rise apartments was carried out in Presint 9, Putrajaya, Malaysia. Ovitraps were placed indoors within four blocks of high-rise apartments from the ground floors (0.0 - 3.0 m) until up to the tenth floors (28.1 - 30.0 m). Aedes aegypti was the dominant species found in the ovitraps (87.85%), while Aedes albopictus was found in lower numbers. From total number of larvae collected (650), 40.92% of these larvae were obtained from the fourth block; Block D. The peak density of Aedes sp. was observed at level 6 (16.1 - …
