It’S My Body: The Biomedical Ethics Of Cell And Organ Harvest,
2012
Providence College
It’S My Body: The Biomedical Ethics Of Cell And Organ Harvest, Christina Perri
Common Reading Essay Contest Winners
First Place
The Injustice Of Ignorance,
2012
Providence College
The Injustice Of Ignorance, Nicholas Tavares
Common Reading Essay Contest Winners
Third Place (tie)
Pursuing Medawar’S Challenge For Full Replacement,
2012
The Humane Society of the United States
Pursuing Medawar’S Challenge For Full Replacement, Martin Stephens
Experimentation Collection
In 1969, Nobel Prize-winning scientist Peter Medawar predicted that scientific innovation would someday fully replace the use of animals in biomedical research. Medawar correctly forecast the leveling off and subsequent decline in animal use in the last quarter of the 20th century – a period of remarkable innovation in the life sciences. A 2007 report by the U.S. National Academy of Sciences, Toxicity Testing in the 21st Century, proposed a strategy that is likely to replace all routine animal use in toxicology with innovative methods within one to two decades. Replacing animal use throughout biomedical research is more challenging given …
A Roadmap For The Development Of Alternative (Non-Animal) Methods For Systemic Toxicity Testing,
2012
DABMEB Consultancy Ltd
A Roadmap For The Development Of Alternative (Non-Animal) Methods For Systemic Toxicity Testing, David Basketter, Harvey Clewell, Ian Kimber, Annamaria Rossi, Bas Blaauboer, Robert Burrier, Mardas Daneshian, Chantra Eskes, Alan Goldberg, Nina Hasiwa, Sebastian Hoffmann, Joanna Jaworska, Thomas B. Knudsen, Robert Landsiedel, Marcel Leist, Paul Locke, Gavin Maxwell, James Mckim, Emily Mcvey, Gladys Ouédraogo, Grace Patlewicz, Olavi Pelkonen, Erwin Roggen, Costanza Rovida, Irmela Ruhdel, Michael Schwarz, Andreas Schepky, Greet Schoeters, Nigel Skinner, Kerstin Trentz, Marian Turner, Philippe Vanparys, James Yager, Joanne Zurlo, Thomas Hartung
Biomedical Research and Alternative Methods Collection
Systemic toxicity testing forms the cornerstone for the safety evaluation of substances. Pressures to move from traditional animal models to novel technologies arise from various concerns, including: the need to evaluate large numbers of previously untested chemicals and new products (such as nanoparticles or cell therapies), the limited predictivity of traditional tests for human health effects, duration and costs of current approaches, and animal welfare considerations. The latter holds especially true in the context of the scheduled 2013 marketing ban on cosmetic ingredients tested for systemic toxicity. Based on a major analysis of the status of alternative methods (Adler et …
Biology Department Newsletter, No.2,
2012
Sacred Heart University
Biology Department Newsletter, No.2, Sacred Heart University
Biology Newsletter
No abstract provided.
An Exhibit Wordle,
2012
University of South Carolina - Columbia
A Crossword Puzzle For Kids,
2012
University of South Carolina - Columbia
Word Find,
2012
University of South Carolina - Columbia
Images From The Exhibit, Page 1,
2012
University of South Carolina - Columbia
Lesson Plans, Activities, And Further Reading,
2012
University of South Carolina - Columbia
Lesson Plans, Activities, And Further Reading, Allison Marsh
Handouts
No abstract provided.
Title Panel,
2012
University of South Carolina - Columbia
Why Do We Collect?,
2012
University of South Carolina - Columbia
Why Do We Collect?, Allison Marsh
Section 2: Imaging the Microscopic
No abstract provided.
Spotlight On Usc: A.C. Moore Herbarium,
2012
University of South Carolina - Columbia
Spotlight On Usc: A.C. Moore Herbarium, Allison Marsh
Section 2: Imaging the Microscopic
No abstract provided.
Imaging And Aesthetics,
2012
University of South Carolina - Columbia
Imaging And Aesthetics, Allison Marsh
Section 2: Imaging the Microscopic
No abstract provided.
Images From The Exhibit, Page 2,
2012
University of South Carolina - Columbia
Characterization Of A Novel Gef Kiaa1362,
2011
Bemidji State University
Characterization Of A Novel Gef Kiaa1362, Emily Roach
Honors Capstones
Capstone submitted as a graduation requirement for the BSU Honors Program.
Hands-On Labs (Hol): Using Technology And Web-Based Resources To Transform A Traditional Lab-Based Biology Course Into A Distance Learning (Dl) Hybrid Course, Across Schools At Pace University.,
2011
Pace University, Dyson College of Arts and Sciences
Hands-On Labs (Hol): Using Technology And Web-Based Resources To Transform A Traditional Lab-Based Biology Course Into A Distance Learning (Dl) Hybrid Course, Across Schools At Pace University., Erica Kipp
Cornerstone 3 Reports : Interdisciplinary Informatics
No abstract provided.
Harnessing Opportunities In Non-Animal Asthma Research For A 21st-Century Science,
2011
Humane Society International
Harnessing Opportunities In Non-Animal Asthma Research For A 21st-Century Science, Gemma L. Buckland
Experimentation Collection
The incidence of asthma is on the increase and calls for research are growing, yet asthma is a disease that scientists are still trying to come to grips with. Asthma research has relied heavily on animal use; however, in light of increasingly robust in vitro and computational models and the need to more fully incorporate the ‘Three Rs’ principles of Replacement, Reduction and Refinement, is it time to reassess the asthma research paradigm? Progress in non-animal research techniques is reaching a level where commitment and integration are necessary. Many scientists believe that progress in this field rests on linking disciplines …
Forward Osmosis Bag: Ground Testing The Prospect Of Using Alternative Water Sources For Drinking Water,
2011
California Polytechnic State University - San Luis Obispo
Forward Osmosis Bag: Ground Testing The Prospect Of Using Alternative Water Sources For Drinking Water, Michaela Marie Brant, Ariella Yendler, Mona Hammoudeh, Michael T. Flynn
STAR Program Research Presentations
On the STS-135 Space Shuttle mission, to be launched July 8, 2011, a forward osmosis bag (FOB) study will be conducted. At NASA Ames this summer, the ground truth testing is being conducted for results comparisons. The FOB technology is derived from a commercial product, the X-Pack water filter. Forward osmosis operates by utilizing an established concentration gradient across a semi-permeable membrane to move water molecules from one side of the membrane to the other. This concept is exploited to harvest drinking water from grey water sources such as urine, sea water, or vehicle water. In this experiment, potassium chloride …
Significance Of Increased Tissue Transglutaminase In Hormone Refractory Prostate Cancer,
2011
The University of Texas Graduate School of Biomedical Sciences at Houston
Significance Of Increased Tissue Transglutaminase In Hormone Refractory Prostate Cancer, Amy L. Han
Dissertations and Theses (Open Access)
The progression of hormone responsive to hormone refractory prostate cancer poses a major clinical challenge in the successful treatment of prostate cancer. The hormone refractory prostate cancer cells exhibit resistance not only to castrate levels of testosterone, but also to other therapeutic modalities and hence become lethal. Currently, there is no effective treatment available for managing this cancer. These observations underscore the urgency to investigate mechanism(s) that contribute to the progression of hormone-responsive to hormone-refractory prostate cancer and to target them for improved clinical outcomes.
Tissue transglutaminase (TG2) is a multifunctional pro-inflammatory protein involved in diverse physiological processes such as …
