Life Sciences Commons^™

Accuracy And Practical Considerations For Doubly Labeled Water Analysis In Nutrition Studies Using A Laser-Based Isotope Instrument (Off-Axis Integrated Cavity Output Spectroscopy), Linda M Reynard, William W Wong, Noreen Tuross

Children’s Nutrition Research Center Staff Publications

Background: Given the utility of the doubly labeled water (DLW) method for determination of energy expenditure, additional techniques for isotope analysis of the samples are welcome. Laser-based instruments are one such new analytical tool, but their accuracy and feasibility for DLW studies are grossly understudied.

Objectives: We assessed the accuracy of laser-based isotope ratio measurements as part of the DLW method for estimation of carbon dioxide production rate (rCO2) and total energy expenditure (TEE), in between-group comparison study designs.

Methods: Urine samples from a previous study were analyzed with a laser-based instrument [off-axis integrated cavity output spectroscopy (OA-ICOS)]. In that …

Cell-Type Specific Expression Of Apolipoprotein E By Astrocytes And Microglia: Implications For The Development Of Amyloid-Β Pathology In Alzheimer Disease, Thomas Mahan

Arts & Sciences Graduate Student Theses and Dissertations

Alzheimer disease (AD) is characterized by two main pathological hallmarks, extracellular amyloid plaques primarily comprised of the amyloid-β (Aβ) peptide, and intracellular neurofibrillary tangles mainly comprised of the tau protein. Although the pathologies underlying AD were first described over one hundred years ago, researchers today are still trying to understand how the development of Aβ pathology is regulated in the hopes of developing more effective treatments. Advances in genetics over the last several decades have allowed for several genetic risk factors to be identified that increase or decrease ones likelihood for developing (AD). Of these genetic risk factors, the strongest …

Cxcl10 Chemokine Regulates Heterogeneity Of The Cd8+ T Cell Response And Viral Set Point During Chronic Infection, Aleksandra J Ozga, Melvyn T Chow, Mateus E Lopes, Rachel L Servis, Mauro Di Pilato, Jeffrey Lian, Andrew D Luster

Faculty, Staff and Student Publications

CD8+ T cells responding to chronic infection adapt an altered differentiation program that provides some restrain on pathogen replication yet limits immunopathology. This adaptation is imprinted in stem-like cells and propagated to their progeny. Understanding the molecular control of CD8+ T cell differentiation in chronic infection has important therapeutic implications. Here, we found that the chemokine receptor CXCR3 was highly expressed on viral-specific stem-like CD8+ T cells and that one of its ligands, CXCL10, regulated the persistence and heterogeneity of responding CD8+ T cells in spleens of mice chronically infected with lymphocytic choriomeningitis virus. CXCL10 was produced by inflammatory monocytes …

Epigenetic Silencing Of Tumor Suppressor Lncrna Nkila: Implication On Nf-Κb Signaling In Non-Hodgkin’S Lymphoma, Min-Yue Zhang, George Calin, Ming-Dan Deng, Rex K H Au-Yeung, Lu-Qian Wang

Faculty, Staff and Student Publications

The long non-coding RNA (lncRNA) NKILA, localized to 20q13.31, is a negative regulator of NF-κB signaling implicated in carcinogenesis. As a CpG island is embedded in the promoter region of NKILA, it is hypothesized as a tumor suppressor lncRNA silenced by promoter DNA methylation in non-Hodgkin’s lymphoma (NHL). By pyrosequencing-verified methylation-specific PCR, NKILA methylation was detected in 1/10 (10%) NHL cell lines, but not in normal peripheral blood buffy coats or tonsils. NKILA methylation correlated with the repression of NKILA in cell lines. Hypomethylation treatment with 5-Aza-2′-deoxycytidine resulted in promoter demethylation and the re-expression of NKILA. In 102 …

Ten Years Of Experience Support Pharmacogenetic Testing To Guide Individualized Drug Therapy., María Celsa Peña-Martín, Belén García-Berrocal, Almudena Sánchez-Martín, Elena Marcos-Vadillo, María Jesús García-Salgado, Santiago Sánchez, Carolina Lorenzo, David González-Parra, Francisco Sans, Manuel Franco, Andrea Gaedigk, María José Mateos-Sexmero, Catalina Sanz, María Isidoro-García

Manuscripts, Articles, Book Chapters and Other Papers

Precision medicine utilizing the genetic information of genes involved in the metabolism and disposition of drugs can not only improve drug efficacy but also prevent or minimize adverse events. Polypharmacy is common among multimorbid patients and is associated with increased adverse events. One of the main objectives in health care is safe and efficacious drug therapy, which is directly correlated to the individual response to treatment. Precision medicine can increase drug safety in many scenarios, including polypharmacy. In this report, we share our experience utilizing precision medicine over the past ten years. Based on our experience using pharmacogenetic (PGx)-informed prescribing, …

Tracking Spatial Regimes In Animal Communities: Implications For Resilience-Based Management, Caleb P. Roberts, Daniel R. Uden, Craig R. Allen, David G. Angeler, Larkin A. Powell, Brady W. Allred, Matthew O. Jones, Jeremy D. Maestas, Dirac L. Twidwell Jr

Department of Agronomy and Horticulture: Faculty Publications

Spatial regimes (the spatial extents of ecological states) exhibit strong spatiotemporal order as they expand or contract in response to retreating or encroaching adjacent spatial regimes (e.g., woody plant invasion of grasslands) and human management (e.g., fire treatments). New methods enable tracking spatial regime boundaries via vegetation landcover data, and this approach is being used for strategic management across biomes. A clear advancement would be incorporating animal community data to track spatial regime boundaries alongside vegetation data. In a 41,170-hectare grassland experiencing woody plant encroachment, we test the utility of using animal community data to track spatial regimes via two …

Wastewater-Based Estimation Of Substances Discharged At The Rest Areas Along The State Highways In Kentucky, Katherine E. Gray, Eugene Shin, Tyler Whitt, Andrew Windhorst, Houston Hampton, Chris Delcher, Bikram Subedi

Posters-at-the-Capitol

The availability of licit and illicit stimulants and its adverse consequences on public health has emerged as a major drug threat to communities in the United States. Despite several drug-involved traffic incidents along the interstate highways, this report represents the first comprehensive and quantitative report of drugs discharged at the rest areas along the interstate highways. In this National Institute of Justice-funded study, the amount of several discharged drugs focusing on stimulants but also including opioids and prescription antipsychotics are being measured in raw wastewater collected from five rest areas and a truck servicing facility using a state-of-the-art mass …

Local Knowledge On The Changes In Vegetation Composition And Abundance In Rusinga Island, Homa Bay County, Kenya, M. N. Nyaga, S. M. Mureithi, V. O. Wasonga, O. K. Koech

IGC Proceedings (1977-2023)

Local communities have been coping with environmental dynamics since time immemorial, and they often possess considerable knowledge about environmental change, as well as mechanisms of coping with the consequences of such changes. Local knowledge on the changes in vegetation composition and abundance is therefore fundamental for the development of management strategies aimed at sustainable use and conservation of natural vegetation resources. Household interviews (n=150), Key informant interviews (n=30) and Focus group discussions (n=4) were used in this study to extract information on the communities’ perceptions on the status of vegetation in Rusinga Island of …

Cloud Computing Solution For Monitoring Arid Rangeland Dynamics: Case Of Moroccan Highlands And Southern Acacia Ecosystems, Said Lahssini, Said Moukrim, H. Mharzi-Alaoui, N. Rifai, L. El Mansouri, F. El Wahidi

IGC Proceedings (1977-2023)

The wide availability of free satellite imagery, the recent development of cloud platforms dedicated to big spatial data (Big Data) that integrates both image archives from different providers, processing algorithms, distributed processing capabilities as well as an application programming interface (API) that facilitate scripting and automation process opened new perspectives for the use of vegetation observation time series over long timestamps and over large spatial scales (almost planetary).

This work aims at harnessing these technologies and building up an automated solution to monitor rangeland rehabilitation dynamics in arid lands and to assess the effectiveness of stakeholder’s management strategies. Such solution …

Characterizing Invasiveness Through A Descriptive Study Of Guinea Grass (Megathyrsus Maximus) Growing In Three Habitat Types And Differing Herbivore Assemblages In Both Kenya And Texas, A. C. Rhodes, R. M. Plowes, D. J. Martins, I. Ng'iru, L. E. Gilbert

IGC Proceedings (1977-2023)

Guinea grass (Megathyrsus maximus syn. Panicum maximum) is an important pasture grass that has been introduced pantropically, yet in many cases has escaped cultivation and is invading native rangelands – threatening biodiversity at multiple trophic levels. An increasing challenge of rangeland management is balancing the importance of pasture grasses with their negative impact on ecosystem processes. Given this challenge, it is critical to understand the mechanisms that underlie grass invasion. In this descriptive study, our objective was to assess the ecological stress release hypothesis by comparing the relative abundance and functional traits of Guinea grass in Kenya's home …

Forty Years, Mary I. Fisher

Physical Therapy Faculty Publications

No abstract provided.

Conversion Of Food Waste Into 2,3-Butanediol Via Thermophilic Fermentation: Effects Of Carbohydrate Content And Nutrient Supplementation, Dajun Yu, Joshua O'Hair, Nicholas Poe, Qing Jin, Sophia Pinton, Yanhong He, Haibo Huang

Biology Faculty Research

Fermentation of food waste into 2,3-butanediol (2,3-BDO), a high-value chemical, is environmentally sustainable and an inexpensive method to recycle waste. Compared to traditional mesophilic fermentation, thermophilic fermentation can inhibit the growth of contaminant bacteria, thereby improving the success of food waste fermentation. However, the effects of sugar and nutrient concentrations in thermophilic food waste fermentations are currently unclear. Here, we investigated the effects of sugar and nutrients (yeast extract (YE) and peptone) concentrations on 2,3-BDO production from fermenting glucose and food waste media using the newly isolated thermophilic Bacillus licheniformis YNP5-TSU. When glucose media was used, fermentation was greatly affected …

Introduction To Epigenetics, Yevgeniy Grigoryev

Open Educational Resources

Syllabus for Bio481 Introduction to Epigenetics

Transcranial Direct Current Stimulation On Parkinson’S Disease: Systematic Review And Meta-Analysis, Paloma Cristina Alves De Oliveira, Thiago Anderson Brito De Araújo, Daniel Gomes Da Silva Machado, Abner Cardoso Rodrigues, Marom Bikson, Suellen Marinho Andrade, Alexandre Hideki Okano, Hougelle Simplicio, Rodrigo Pegado, Edgard Morya

Publications and Research

Background: Clinical impact of transcranial direct current stimulation (tDCS) alone for Parkinson’s disease (PD) is still a challenge. Thus, there is a need to synthesize available results, analyze methodologically and statistically, and provide evidence to guide tDCS in PD.

Objective: Investigate isolated tDCS effect in different brain areas and number of stimulated targets on PD motor symptoms.

Methods: A systematic review was carried out up to February 2021, in databases: Cochrane Library, EMBASE, PubMed/MEDLINE, Scopus, and Web of science. Full text articles evaluating effect of active tDCS (anodic or cathodic) vs. sham or control on motor symptoms of PD were …

Investigating The Effects Of Climate Change On The Phenology Of Achillea Millefolium, Aquilegia Coerulea, And Penstemon Cyanocaulis, Hannah O’Toole, Kailey Hicks, Lisa Long, Jackson Garske, Anna Sher

DU Undergraduate Research Journal Archive

As the effects of climate change are starting to unearth themselves, the impacts can be observed by tracking the patterns of cyclical natural phenomena also known as phenology, and monitoring how they have changed over time. These cycles are at the crux of making ecosystems viable for their local biodiversity, and understanding the ongoing change allows for further understanding of the ecosystem’s change over time. In this study, we look at the ordinal flowering dates of the Achillea millefolium, Aquilegia coerulea, and Penstemon cyanocaulis over the past century. Our data give insight into how warmer temperatures occurring earlier in …

Feature Papers In Horticulturae, Douglas D. Archbold

Horticulture Faculty Publications

No abstract provided.

Colored Sweet Bell And Tapered Pepper Cultivar Evaluation For High Tunnel Production In West-Central Indiana, 2021, Petrus Langenhoven

Midwest Vegetable Trial Reports

Pepper production in high tunnels during the summer is very popular. The high tunnels lower the incidence of foliar disease, protect the crop against severe weather conditions and it extends the production season into the fall. Production of summer crops is generally high in an unheated high tunnel. However, information is lacking about varieties that are adapted for high tunnel production in Indiana. In this paper, we report on five sweet bell and five tapered pepper entries that were evaluated at the Purdue Student Farm, West Lafayette, Indiana.

A Nationwide Virtual Research Education Program For Medical Students In Pakistan: Methodological Framework, Feasibility Testing, And Outcomes, Ali Aahil Noorali, Maha Inam, Hamna Shahbaz, Hareem Rauf, Faiqa Binte Aamir, Farah Khalid, Saadia Abbas, Abdullah Saeed, Muhammad Daniyal Musharraf, Asma Altaf Hussain Merchant, Babar Hasan, Muneera A. Rasheed, Fyezah Jehan, Muhammad Tariq, Adil Hussain Haider

Medical College Documents

Introduction: Equipping young medical trainees with fundamental research skills can be a promising strategy to address the need for professionals who can understand and responsibly communicate evolving scientific evidence during a pandemic. Despite an ardent interest to partake in research, most educational institutions in Pakistan and other low-middle income countries have not yet adopted a comprehensive strategy for research skills education. The authors aimed to design and assess the feasibility of implementing the first nation-wide virtual research workshop for medical students in Pakistan.
Methods: The course "Beginners Guide to Research," designed as a nation-wide virtual research workshop series, was conducted …

Total Energy Expenditure Is Repeatable In Adults But Not Associated With Short-Term Changes In Body Composition, Rebecca Rimbach, Yosuke Yamada, Hiroyuki Sagayama, Philip N Ainslie, Lene F Anderson, Liam J Anderson, Lenore Arab, Issaad Baddou, Kweku Bedu-Addo, Ellen E Blaak, Stephane Blanc, Alberto G Bonomi, Carlijn V C Bouten, Pascal Bovet, Maciej S Buchowski, Nancy F Butte, Stefan G J A Camps, Graeme L Close, Jamie A Cooper, Sai Krupa Das, Lara R Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W Fudge, Annelies H Goris, Michael Gurven, Catherine Hambly, Asmaa El Hamdouchi, Marije B Hoos, Sumei Hu, Noorjehan Joonas, Annemiek M Joosen, Peter Katzmarzyk, Kitty P Kempen, Misaka Kimura, William E Kraus, Robert F Kushner, Estelle V Lambert, William R Leonard, Nader Lessan, Corby K Martin, Anine C Medin, Erwin P Meijer, James C Morehen, James P Morton, Marian L Neuhouser, Theresa A Nicklas, Robert M Ojiambo, Kirsi H Pietiläinen, Yannis P Pitsiladis, Jacob Plange-Rhule, Guy Plasqui, Ross L Prentice, Roberto A Rabinovich, Susan B Racette, David A Raichlen, Eric Ravussin, Rebecca M Reynolds, Susan B Roberts, Albertine J Schuit, Anders M Sjödin, Eric Stice, Samuel S Urlacher, Giulio Valenti, Ludo M Van Etten, Edgar A Van Mil, Jonathan C K Wells, George Wilson, Brian M Wood, Jack Yanovski, Tsukasa Yoshida, Xueying Zhang, Alexia J Murphy-Alford, Cornelia U Loechl, Amy H Luke, Jennifer Rood, Dale A Schoeller, Klaas R Westerterp, William W Wong, John R Speakman, Herman Pontzer

Children’s Nutrition Research Center Staff Publications

Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, a critical variable in longitudinal studies of energy balance, is understudied. We examine repeated doubly labeled water (DLW) measurements of TEE in 348 adults and 47 children from the IAEA DLW Database (mean ± SD time interval: 1.9 ± 2.9 y) to assess repeatability of TEE, and to examine if TEE adjusted for age, sex, fat-free mass, and fat mass is associated with changes in weight or body composition. Here, we report that repeatability of TEE is high for adults, but …

The Allergy Mediator Histamine Confers Resistance To Immunotherapy In Cancer Patients Via Activation Of The Macrophage Histamine Receptor H1, Xiangliang Yuan, Yuan Zhang, Xuedong Yin, Yohei Saito, Huihui Fan, Ping Li, Wen-Ling Kuo, Angela Halpin, Don L Gibbons, Hideo Yagita, Zhongming Zhao, Da Pang, Guosheng Ren, Cassian Yee, J Jack Lee, Dihua Yu

Faculty, Staff and Student Publications

Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective analyses revealed that cancer patients who took antihistamines during immunotherapy treatment had significantly improved survival. We uncovered that histamine and histamine receptor H1 (HRH1) are frequently increased in the tumor microenvironment and induce T cell dysfunction. Mechanistically, HRH1-activated macrophages polarize toward an M2-like immunosuppressive phenotype with increased expression of the immune checkpoint VISTA, rendering T cells dysfunctional. HRH1 knockout or antihistamine treatment reverted macrophage immunosuppression, revitalized T cell cytotoxic function, and restored immunotherapy response. Allergy, via the histamine-HRH1 axis, facilitated tumor growth and induced immunotherapy resistance in mice and humans. …

Emory-Tibet Science Initiative: Changes In Monastic Science Learning Motivation And Engagement During A Six-Year Curriculum, Kelsey M. Gray, Cindy Achat-Mendes, Ann Cale Kruger, Tashi Lhamo, Rinchen Wangyal, Gelek Gyatso, Carol M. Worthman

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Led by His Holiness the Dalai Lama, the initiative taken by the Tibetan Buddhist monastic community to connect with western science and scientists presents a unique opportunity to understand the motivations and engagement behaviors that contribute to monastic science learning. In this study, we draw on quantitative data from two distinct surveys that track motivations and engagement behaviors related to science education among monastic students. The first survey was administered at one monastic university in 2018, and the second follow-up survey was completed by students at two monastic universities in 2019. These surveys assessed the reception of science education related …

Natural History Of The Guatemalan Copper Iophanus Pyrrhias (Godman And Salvin, 1887) (Lepidoptera: Lycaenidae) In Guatemala, José Monzón-Sierra, Gregory C. Ballmer

The Taxonomic Report of the International Lepidoptera Survey

Abstract

Detailed information including photographs about the natural history of Iophanus pyrrhias (Godman and Salvin 1887) in Guatemala is presented. Information includes geographic and altitudinal distribution and phenology. We reconfirm the immatures stages use Muehlenbeckia tamnifolia (Kunth) Meisn., 1841 (Polygonaceae) as the host plant.

Reusmen

Se presenta información detallada incluyendo fotografías de la historia natural de Iophanus pyrrhias (Godman y Salvin 1887) en Guatemala. La información incluye distribución geográfica y altitudinal y fenología. Confirmamos que los estados inmaduros se alimentan de Muehlenbeckia tamnifolia (Kunth) Meisn., 1841 (Polygonaceae).

The Allergy Mediator Histamine Confers Resistance To Immunotherapy In Cancer Patients Via Activation Of The Macrophage Histamine Receptor H1, Hongzhong Li, Yi Xiao, Qin Li, Jun Yao, Xiangliang Yuan, Yuan Zhang, Xuedong Yin, Yohei Saito, Huihui Fan, Ping Li, Wen-Ling Kuo, Angela Halpin, Don L Gibbons, Hideo Yagita, Zhongming Zhao, Da Pang, Guosheng Ren, Cassian Yee, J Jack Lee, Dihua Yu

Duncan NRI Faculty and Staff Publications

Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective analyses revealed that cancer patients who took antihistamines during immunotherapy treatment had significantly improved survival. We uncovered that histamine and histamine receptor H1 (HRH1) are frequently increased in the tumor microenvironment and induce T cell dysfunction. Mechanistically, HRH1-activated macrophages polarize toward an M2-like immunosuppressive phenotype with increased expression of the immune checkpoint VISTA, rendering T cells dysfunctional. HRH1 knockout or antihistamine treatment reverted macrophage immunosuppression, revitalized T cell cytotoxic function, and restored immunotherapy response. Allergy, via the histamine-HRH1 axis, facilitated tumor growth and induced immunotherapy resistance in mice and humans. …

The Allergy Mediator Histamine Confers Resistance To Immunotherapy In Cancer Patients Via Activation Of The Macrophage Histamine Receptor H1, Hongzhong Li, Yi Xiao, Qin Li, Jun Yao, Xiangliang Yuan, Xuedong Yin, Huihui Fan, Ping Li, Wen-Ling Kuo, Angela Halpin, Don L Gibbons, Hideo Yagita, Zhongming Zhao, Da Pang, Guosheng Ren, Cassian Yee, J Jack Lee, Dihua Yu

Faculty, Staff and Student Publications

Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective analyses revealed that cancer patients who took antihistamines during immunotherapy treatment had significantly improved survival. We uncovered that histamine and histamine receptor H1 (HRH1) are frequently increased in the tumor microenvironment and induce T cell dysfunction. Mechanistically, HRH1-activated macrophages polarize toward an M2-like immunosuppressive phenotype with increased expression of the immune checkpoint VISTA, rendering T cells dysfunctional. HRH1 knockout or antihistamine treatment reverted macrophage immunosuppression, revitalized T cell cytotoxic function, and restored immunotherapy response. Allergy, via the histamine-HRH1 axis, facilitated tumor growth and induced immunotherapy resistance in mice and humans. …

Seeding The Way: A Guide To Restoring Native Plants In Great Salt Lake Wetlands, Emily Tarsa, Rae Robinson, Coryna Hebert, David England, Keith Hambrecht, Chad Cranney, Karin Kettenring

All Current Publications

From densely vegetated marshes to sparse patches of playa vegetation, native plants of Great Salt Lake drive healthy wetlands. They provide habitat, cover, and food for the many birds, amphibians, insects, and mammals that call these wetlands home. Disturbances to these wetlands, such as treating invasive Phragmites australis or building dikes, can impact native plant communities. Reestablishing native vegetation is critical to rebuilding healthy wetlands. Though there is still much to be learned, here we have summarized our knowledge of the "what, where, and how" of native plant revegetation in these wetlands, specifically using native seed. This guide is intended …

Can High Density, Short Duration Grazing Replace Fire In A South African Mesic Grassland?, N. M. Chonco, S. C. Nkuna

IGC Proceedings (1977-2023)

High density grazing (HDG), defined as the concentration of many livestock on a small area for a short period of time has become increasingly popular in the South African mesic grassland yet little is known about it impact. HDG is usually applied without fire, based on the assertion that it is a key contributor to desertification of grasslands. However, fire plays an important role in the development and growth of most South African mesic grassland plant species, as it stimulates resprouting and reduces competition for light. The aim of this study was to determine the impacts of high density grazing …

Back To The Roots - Do Traditional Maasai Management Strategies Work Towards Resilience Against Unpredictable Rainfall And Grazing Pressure In Northern Tanzania?, S. A. Baumgartner, A. C. Treydte

IGC Proceedings (1977-2023)

Despite the importance for people´s livelihoods, many semi-arid African savannas are prone to heavy degradation due to overutilization by people, livestock and increased climate variability. Rangeland management, such as transhumance and deferred grazing systems, practiced by the Maasai in northern Tanzania, can be useful in combating the negative consequences of overuse and increasing rainfall variability. But little is known on how different rangeland regimes, practiced by the Maasai, impacts the productivity of these rangelands.

We collected data on regrowth rates under different rangeland management regimes (rainy season grazing land, dry season grazing land, and seasonal exclosures), different harvest rates (month, …

Assessment Of Rangeland Condition In A Dryland System Using Uav-Based Multispectral Imagery, V. Amputu, K. Tielbörger, N. Knox

IGC Proceedings (1977-2023)

Dry savannahs are water-limited and under increasing anthropogenic pressure. Thus, considering climate change and the unprecedented pace and scale of rangeland deterioration, we need methods for assessing the status of such rangelands that are easy to apply, yield reliable and repeatable results that can be applied over large spatial scales. Global and local scale monitoring of rangelands through satellite data and labour-intensive field measurements respectively, are limited in accurately assessing the spatiotemporal heterogeneity of vegetation dynamics to provide crucial information that detects degradation in its early stages. Fortunately, newly emerging techniques such as unmanned aerial vehicles (UAVs), associated miniaturized sensors …

An Integrated Framework To Study Ecological Tipping Points In Social-Ecological Systems, F. A. Männer, L.-M. Schwarz, D. A. Menestrey-Schwieger, V. Amputu, M. C. Bilton, K. Brinkmann, G. Dressler, N. Hamunyela, H. Heita, S. Heshmati, S. Liehr, M. Mbidzo, F. Munyebvu-Chambara, W. C. Nesongano, M. Rauchecker, A. Sandhage-Hofmann, K. Tielbörger, K. Zimmer, A. Linstädter

IGC Proceedings (1977-2023)

Sudden regime shifts or tipping points pose a major threat to various ecosystems and people's livelihoods worldwide. However, tipping points are still hard to predict and often occur without warning. To avoid dramatic social-ecological consequences, it is crucial to understand tipping point behaviour and to identify early warning indicators. Previous studies have hardly implemented an integrated social-ecological approach, which has led to a fragmented understanding and oversimplification of tipping point phenomena. Against this background, we present a systemic research framework that harmonizes ecological and social perspectives to gain a mechanistic understanding of tipping point behaviour. We utilize a social-ecological systems …

An Integrated Assessment And Management Optimization System For Grazinglands, D. Toledo, J. E. Herrick, S. Goslee, M. Sanderson

IGC Proceedings (1977-2023)

Rangelands and pasturelands are often assessed using different methodologies. The Interpreting Indicators of Rangeland Health and Pasture Condition Scoring methodologies, two techniques used widely across the USA, were developed for rangelands and pasturelands respectively. These two grazingland assessment techniques were determined to be complementary and if integrated could provide an optimized approach to measure grazinglands without regards to specific use (i.e. range or pasture). We present an improved grazingland assessment protocol that merges indicators and attributes from Interpreting Indicators of Rangeland Health and Pasture Condition Scoring methodologies. This Integrated Grazingland Assessment (IGA) approach allows evaluators to assess site conditions and …