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Wright State University

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Articles 1 - 30 of 1987

Full-Text Articles in Life Sciences

Extension Of Range: First Report Of Oriental Pied Hornbill (Anthracoceros Albirostris) In Pakistan, Ghulam Rasool Awan, Muhammad Altaf, Abdul Majid Khan, Muhammad Imran, Muhammad Junaid, Altaf Hussain Nerajo Sep 2026

Extension Of Range: First Report Of Oriental Pied Hornbill (Anthracoceros Albirostris) In Pakistan, Ghulam Rasool Awan, Muhammad Altaf, Abdul Majid Khan, Muhammad Imran, Muhammad Junaid, Altaf Hussain Nerajo

Journal of Bioresource Management

The IUCN Red List of Threatened Species last classified the Oriental Pied Hornbill (Anthracoceros albirostris) as "Least Concern" (LC) in 2026. This study aims to establish a new provincial record of the Oriental Pied Hornbill in Pakistan, close a major distributional gap, update the species' national presence map, and improve our knowledge of its migratory relationships and habitat use within Pakistan's ecosystems. On 5th July 2016, field surveys for bird photography were carried out along the Ravi River in Lahore, Pakistan. The Oriental Pied Hornbill belongs to the Bucerotidae family and is a large, canopy-dwelling bird. Among …


Evaluation Of Polycyclic Aromatic Hydrocarbon Profiles In Fermented Artemisia Annua Leaf Extract, Mabitine Daniel Malo, Ohemu Adaofoyi Isaiah, Igaznda Terhemba James, Obamuwe Rebecca Joy, Ugber Erdoo Charity, Itodo Monday Christopher Sep 2026

Evaluation Of Polycyclic Aromatic Hydrocarbon Profiles In Fermented Artemisia Annua Leaf Extract, Mabitine Daniel Malo, Ohemu Adaofoyi Isaiah, Igaznda Terhemba James, Obamuwe Rebecca Joy, Ugber Erdoo Charity, Itodo Monday Christopher

Journal of Bioresource Management

This study evaluated the presence, profile and concentration of polycyclic aromatic hydrocarbons (PAHs) in the fermented leaf extract of Artemisia annua, a medicinal plant widely used for its antimalarial and skin-benefiting properties. Given the plant’s increased use in Nigerian traditional medicine, this research examines how fermentation a process known to enhance bioactive compound availability may influence PAH levels, which are of concern due to their carcinogenic, mutagenic, and teratogenic effects. The A. annua leaves were fermented using Saccharomyces cerevisiae cultures and subsequently analyzed using Gas Chromatography-Mass Spectrometry (GC-MS) to detect and quantify PAHs. The analysis identified 24 distinct PAH …


A Single-Step Plate Method For The Screening Of Xyl-A Mutant Libraries Based On Gene Expression, Bilqees Fatima, Muhammad Mohsin Javed Sep 2026

A Single-Step Plate Method For The Screening Of Xyl-A Mutant Libraries Based On Gene Expression, Bilqees Fatima, Muhammad Mohsin Javed

Journal of Bioresource Management

A single-step plate method is described for the screening of transformants of cloned gene xyl-A encoding xylose isomerase. It is rapid, inexpensive, easy to perform, and more specific, as the selection is based on xyl-A expression level. The crucial composition of the plate medium comprised agar, buffer, nutrients, co-factor, substrate, inducer, antibiotic, and an indicator, i.e., 2, 3, 5-triphenyl tetrazolium chloride (TTC). Transformed cells of E. coli BL21 (DE3) with a plasmid (pET21(a)++xyl-A), were exclusively capable of growing, isomerizing the substrate, and producing deep-red formazan by reducing TTC, whereas the untransformed cells and cells containing a …


Bioinformatics-Driven Structural And Functional Characterization Of Caffeine Synthase (Ccs1), Asia Khalil, Muhammad Naveed, Raja Muhammad Ahmad, Sania Saeed, Ayesha Hameed, Ayman Iqbal, Fakhra Nazir Sep 2026

Bioinformatics-Driven Structural And Functional Characterization Of Caffeine Synthase (Ccs1), Asia Khalil, Muhammad Naveed, Raja Muhammad Ahmad, Sania Saeed, Ayesha Hameed, Ayman Iqbal, Fakhra Nazir

Journal of Bioresource Management

Caffeine synthase (CCS1; EC 2.1.1.160) is a S-adenosyl-L-methionine (SAM; S-adenosyl-L-methionine) dependent N-methyltransferase that executes the final methylation steps of caffeine biosynthesis in coffee, tea, and related plants. While paraxanthine can act as an efficient substrate, it contributes to a comparatively minor branch in the overall pathway. We conducted an integrated in silico analysis of CCS1, covering sequence retrieval, structure prediction, 3D modeling, and mutation assessment. Secondary structure was inferred using PSIPRED; physicochemical indices were computed via AA-PROP; 3D models were generated by I-TASSER and evaluated by Verify3D; and missense effects were prioritized using PolyPhen-2, PROVEAN, I-Mutant, and PhD-SNP. Taken together, …


The Effect Of Alpha-Lipoic Acid On Sperm Cryobiology And Post-Thaw Quality Of Sperm In Livestock Species, Kashif Ali Malak, Nazar Ali Korejo, Hira Sajjad Talpur, Asmatullah Kaka, Atif Ali Malak, Muhammad Aqeel, Rasool Bux Sep 2026

The Effect Of Alpha-Lipoic Acid On Sperm Cryobiology And Post-Thaw Quality Of Sperm In Livestock Species, Kashif Ali Malak, Nazar Ali Korejo, Hira Sajjad Talpur, Asmatullah Kaka, Atif Ali Malak, Muhammad Aqeel, Rasool Bux

Journal of Bioresource Management

The cryopreservation of semen is a prerequisite for artificial insemination, germplasm banking and the global distribution of elite livestock breeding. However, spermatozoa are particularly sensitive to cooling and freezing/thawing processes due to the presence of large amounts of polyunsaturated fatty acids in their plasma membranes and limited cytoplasmic antioxidant stores. An increase in reactive oxygen species, lipid peroxidation, mitochondrial dysfunction, acrosomal injury and DNA fragmentation occurs due to stress associated with cryopreservation, which results in the lowering of motility as well as viability and post-thaw low quality of sperm. Alpha-lipoic acid is a natural disulfide compound that acts as a …


Carbon Sequestration Potential Of Urban Green Spaces In Guinea Savanna Area Of Nigeria, Alexander Terdoo Akighirga, Babatunde Saheed Bada, Abiodun Olusegun Oladoye, Benard Bunde Meer, Dau Henry Japheth Sep 2026

Carbon Sequestration Potential Of Urban Green Spaces In Guinea Savanna Area Of Nigeria, Alexander Terdoo Akighirga, Babatunde Saheed Bada, Abiodun Olusegun Oladoye, Benard Bunde Meer, Dau Henry Japheth

Journal of Bioresource Management

Rapid urbanization and associated emissions have increased the need to quantify the carbon-storage role of urban green spaces. This study assessed the carbon sequestration potential of roadside tree corridors in Makurdi, within Nigeria’s Guinea Savanna Zone. In this study, sequestration potential denotes standing above-ground carbon stock and carbon dioxide-equivalent stock rather than an annual rate. Six 2 km road segments were purposively selected, and all live trees with diameter at breast height ≥10 cm within a 2 m-wide band on both sides were inventoried, covering 4.8 ha. Stem diameters at the base, middle and upper sections and total height were …


Multivariate Ecological Assessment Of Flora Of Village Karri Haider, District Tank, Kp, Numan Khan, Muhammad Azeem, Muhammad Adnan Hamza, Muhammad Aleem, Arshad Rasool, Ammara Wakeel, Sehrish Sadia Sep 2026

Multivariate Ecological Assessment Of Flora Of Village Karri Haider, District Tank, Kp, Numan Khan, Muhammad Azeem, Muhammad Adnan Hamza, Muhammad Aleem, Arshad Rasool, Ammara Wakeel, Sehrish Sadia

Journal of Bioresource Management

Spatial and temporal patterns of vegetation change are influenced by multiple factors, including the physical environment, land-use history, prior disturbance, and initial vegetation composition. The primary aim of this study was to understand floristic vegetation features, species diversity, and the classification of plant communities in Village Karri Haider, District Tank, Khyber Pakhtunkhwa (KP). Samples were collected from each transect using quadrats of 1 m × 1 m for herbs. Soil from three quadrats was mixed to make composite samples, and soil elements were quantified through laboratory analyses. Two surveys were conducted from July to December, 2023. In the first survey, …


Ecological And Public Health Consequences Of Sand Mining In Aquatic Ecosystems: A Systematic Review, Uduak Sylvanus Jacob, Isangedighi Asuquo Isangedighi, Olusola Abayomi Akangbe, Emmanuel Dami Omogbemi Sep 2026

Ecological And Public Health Consequences Of Sand Mining In Aquatic Ecosystems: A Systematic Review, Uduak Sylvanus Jacob, Isangedighi Asuquo Isangedighi, Olusola Abayomi Akangbe, Emmanuel Dami Omogbemi

Journal of Bioresource Management

The persistent exploitation of the aquatic ecosystem, driven by increasing demand for aquatic resources, including construction-grade sand, is evidenced by hydrological and geomorphological degradation of the aquatic ecosystem, with severe negative consequences on the fauna and flora communities. The rising global demand for sand and inefficient mining regulations have resulted in indiscriminate and illegal sand mining globally. However, developing an effective policy framework for sustained river sand mining requires local, regional, and global data (both qualitative and quantitative) on the status, drivers and implications of sand mining. This paper uses a systematic literature review approach to compile the ecological and …


Establishing Reference Values Of Haematological And Biochemical Blood Parameters In Kundhi Buffalo, Jahan Zaib Ahmed, Jamila Soomro, Moolchand Malhi, Mansoor Tariq, Saba Parveen, Abdul Salam Khoso Sep 2026

Establishing Reference Values Of Haematological And Biochemical Blood Parameters In Kundhi Buffalo, Jahan Zaib Ahmed, Jamila Soomro, Moolchand Malhi, Mansoor Tariq, Saba Parveen, Abdul Salam Khoso

Journal of Bioresource Management

This study aims to establish haematological, biochemical parameters of healthy Kundhi buffalo calves from different areas of Hyderabad, Pakistan, under field conditions. The study was conducted on one hundred twenty (120) buffalo calves of both sexes, ranging in age from 03 to 12 months were chosen at random and divided into three age groups: 03-06 months, 07-09 months and10-12 months with both males and females represented in each group. Female calves from 07-09 months had the highest levels of hematological parameters such as hemoglobin concentration, packed cell volume, white blood cell count, red blood cell count and platelets count, where …


Distribution And Diversity Of Ponyfishes (Perciformes, Leiognathidae) In The Waters Of Sonmiani’S Bay, Balochistan, Pakistan, Noor Hawa, Noor Us Saher Sep 2026

Distribution And Diversity Of Ponyfishes (Perciformes, Leiognathidae) In The Waters Of Sonmiani’S Bay, Balochistan, Pakistan, Noor Hawa, Noor Us Saher

Journal of Bioresource Management

The current research was conducted during October 2020 to September 2021 in bay waters of Sonmiani, Balochistan as aimed to fill the paucity of diversity and distribution of research for the bay waters. Monthly fish samples were collected using gill net and beach seine during high and low tide. In the present study, out of nine species, the six species were identified as a new report species belongs to Leiognathidae family. Secutor interruptus (N=132) was the most abundant species whereas the least abundant species collected during the study period was Karalla daura (N=1). Highest diversity (1.37) was estimated during the …


Saffron By-Products As Underused Resources: An Ethnobotanical Survey And Phytochemical Study In The Taliouine Region, Zineb Khadfy, Rachid Mamouni, Sm Jadouali, Imane Kasimi, Hajar Atifi, Abd Elghani Tahiri, Youssef Karra Sep 2026

Saffron By-Products As Underused Resources: An Ethnobotanical Survey And Phytochemical Study In The Taliouine Region, Zineb Khadfy, Rachid Mamouni, Sm Jadouali, Imane Kasimi, Hajar Atifi, Abd Elghani Tahiri, Youssef Karra

Journal of Bioresource Management

Saffron (Crocus sativus ) is a very traditional plant in Morocco, especially in the Taliouine region. Saffron stigmas are traditionally used as a food additive due to their secondary metabolites. Our study aims to assess the traditional uses of saffron by-products, generated after the harvest of saffron stigmas, by local populations of Taliouine and regions. An ethnobotanical survey was conducted with 42 local people in six communities. The survey consisted of two parts: the first part was about the demographic information of the respondents (name, age, sex, and level of education.). While the second part concerns questions that target …


Evaluating Waste Reduction Efficiency Of Black Soldier Fly Larvae (Bsfl) On Different Waste Types: A Comparative Study On Kitchen, Fruit, And Vegetable Waste, Hannah Mawutor Attipoe, Yvonne Afua Sika Adjei, Sharon Gyekyewaa Asare, Obadiah Opoku-Bamfoh, Gifty Boakye Appiah, Ndep Ntui Asundep, Sandra Abankwa Kwarteng Sep 2026

Evaluating Waste Reduction Efficiency Of Black Soldier Fly Larvae (Bsfl) On Different Waste Types: A Comparative Study On Kitchen, Fruit, And Vegetable Waste, Hannah Mawutor Attipoe, Yvonne Afua Sika Adjei, Sharon Gyekyewaa Asare, Obadiah Opoku-Bamfoh, Gifty Boakye Appiah, Ndep Ntui Asundep, Sandra Abankwa Kwarteng

Journal of Bioresource Management

In many developing countries, food waste constitutes a significant share of municipal solid waste and is often poorly managed, causing environmental degradation. Black Soldier Fly Larvae (BSFL), Hermetia illucens, have emerged as a promising tool for the bioconversion of organic waste. This study evaluated the waste reduction efficiency of BSFL reared on kitchen, fruit, and vegetable wastes and assessed the effect of larval density. Each waste type was subjected to four larval densities (450, 650, 850, and 1050 larvae), with larvae- free treatments serving as controls. Each feeding consisted of 700 g of waste, supplied every four days over a …


Effects Of Dietary Nigella Sativa Supplementation On Growth Performance, Lipid Profile, Carcass Traits, And Immune Response Of Broiler Chickens During Summer And Winter Seasons, Zahida Jabeen, Roheela Yasmeen Sep 2026

Effects Of Dietary Nigella Sativa Supplementation On Growth Performance, Lipid Profile, Carcass Traits, And Immune Response Of Broiler Chickens During Summer And Winter Seasons, Zahida Jabeen, Roheela Yasmeen

Journal of Bioresource Management

The poultry industry is a major agro-based sector in Pakistan and an important source of meat protein. Nigella sativa (black cumin/kalonji) has gained attention as a natural feed additive because of its antimicrobial, antioxidant, immunomodulatory, and growth-promoting properties. This study evaluated the effects of dietary Nigella sativa seed supplementation on growth performance, feed conversion ratio (FCR), lipid profile, and carcass characteristics of broiler chickens under summer and winter conditions. A total of 120 one-day-old broiler chicks were randomly assigned to two dietary treatments, with 60 birds per treatment and three replicates of 20 birds. The control group received a basal …


Risk Assessment And Distribution Of Haemoparasitism In Indigenous Achai And Crossbred Cattle In Lowland Areas Of Northern Hindukush Mountains, Muhammad Zahid Shah, Maaz Saleem, Zia Ur Rehman Khalil Sep 2026

Risk Assessment And Distribution Of Haemoparasitism In Indigenous Achai And Crossbred Cattle In Lowland Areas Of Northern Hindukush Mountains, Muhammad Zahid Shah, Maaz Saleem, Zia Ur Rehman Khalil

Journal of Bioresource Management

The current study was conducted in low land area of Northern Hindukush region to explore the prevalence of blood parasites in in indigenous Achai and it’s crossbred with Jersey cattle associated with different risk factors like breed, gender, age, herd size, feeding system and deworming. A total (n= 250) blood samples were collected from different cattle. Giemsa stain was used to assess the presence of blood parasites eggs or ova. Results revealed an overall prevalence of 43.6 % (109/250) in the study area. Crossbred were found more susceptible to heamoparasitism than indigenous Achai cattle (34.0%, P= .008), while female cattle …


Genetic Improvement Of Wheat (Triticum Aestivum L.) For Enhancing Grain Yield And Adaptability Under Changing Climate, Muhammad Umer Farooq, Fida Hussain, Mehvish Makhdoom, Najaf Batool, Javed Ahmad, Muhammad Ibrahim Khan, Minahel Shahzadi Sep 2026

Genetic Improvement Of Wheat (Triticum Aestivum L.) For Enhancing Grain Yield And Adaptability Under Changing Climate, Muhammad Umer Farooq, Fida Hussain, Mehvish Makhdoom, Najaf Batool, Javed Ahmad, Muhammad Ibrahim Khan, Minahel Shahzadi

Journal of Bioresource Management

Wheat (Triticum aestivum L.) is a fundamental major crop that serves a critical role in ensuring worldwide food availability and sustainability, particularly in developing countries such as Pakistan. Its productivity and yield stability are increasingly threatened by climate change induced stresses such as heat, drought, salinity, evolving pests and disease dynamics. These abiotic and biotic stresses disturb key biological and developmental processes, consequently leading to a decline in grain production and quality. This review synthesizes recent advances in wheat genetic improvement, focusing on breeding strategies and emerging technologies for enhancing grain yield and climate resilience. i.e., how genetic variation, …


Efficacy Of Natural Plant Extracts Against Varroa Mite Infestation In Honey Bee (Apis Mellifera L.), Muhammad Farrukh Mushtaq, Amir Said, Abdul Majid Khan, Mahnoor Arshad, Muhammad Ammar, Abdullah ., Muhammad Farhan Nasir, Amina Bashir, Shumaila Noreen Sep 2026

Efficacy Of Natural Plant Extracts Against Varroa Mite Infestation In Honey Bee (Apis Mellifera L.), Muhammad Farrukh Mushtaq, Amir Said, Abdul Majid Khan, Mahnoor Arshad, Muhammad Ammar, Abdullah ., Muhammad Farhan Nasir, Amina Bashir, Shumaila Noreen

Journal of Bioresource Management

The honeybee, Apis mellifera, is one of the most beneficial insects worldwide. Several factors stress this pollinating insect, with Varroa destructor infestation being one of the most devastating reasons. Conventional acaricides necessitate an alternative control due to the development of resistance and the accumulation of residues. Many plant extracts and oils provide a favourable solution for managing mites in honey bee colonies. This study focused on the acaricidal and insecticidal activities of three plant extracts: Indian rennet (Withania coagulans), Guggal (Commiphora wightii), and Celery (Apium graveolens) against Varroa and potential side effects on …


Molecular Mechanisms, Evidence Levels, And Translational Prospects Of Natural Products In Non-Small Cell Lung Cancer: A Critical Narrative Review, Sakhawat Hussain, Muhammad Yousif, Habibullah Janyaro, Zahid Iqbat Rajput, Mohammad Farooque Hassan Sep 2026

Molecular Mechanisms, Evidence Levels, And Translational Prospects Of Natural Products In Non-Small Cell Lung Cancer: A Critical Narrative Review, Sakhawat Hussain, Muhammad Yousif, Habibullah Janyaro, Zahid Iqbat Rajput, Mohammad Farooque Hassan

Journal of Bioresource Management

Non-small cell lung cancer (NSCLC) accounts for approximately 80–85% of lung cancers and remains a major cause of cancer mortality. Molecular heterogeneity, acquired resistance to targeted therapies, immune escape, and treatment-related toxicity continue to limit durable disease control. Natural products and standardized botanical formulations have contributed substantially to anticancer drug discovery and are being investigated as complementary approaches in NSCLC; however, the strength of evidence varies markedly across experimental and clinical settings. This critical narrative review evaluates molecular mechanisms, preclinical evidence, human studies, and translational barriers relevant to natural-product-based interventions in NSCLC. A structured literature update was performed in August …


Antiplasmodial Activity Of Detarium Senegalense J.F.Gmel. (Fabaceae) Stembark Ethanol Extract, Cletus Anes Ukwubile, Hananiya Hamza Milagawanda Sep 2026

Antiplasmodial Activity Of Detarium Senegalense J.F.Gmel. (Fabaceae) Stembark Ethanol Extract, Cletus Anes Ukwubile, Hananiya Hamza Milagawanda

Journal of Bioresource Management

Malaria is a persistent public health impediment in sub-Saharan Africa, necessitating an incessant search for new, effective, and low-cost antimalarial agents from medicinal plants. This study was designed to evaluate the antiplasmodial efficacy of the ethanol crude extract of the stembark of Detarium senegalense. Standard methods were employed to identify the major secondary metabolites. In vivo antiplasmodial activity of the extract in Plasmodium berghei-infected mice was carried out as per the standard suppression test. The LD50 was elicited in mice using a standard procedure. Phytochemical analysis revealed the presence of important bioactive components such as alkaloids, flavonoids, …


A Review On Nanoparticles: Classification And Roles In Plant Systems, Muhammad Junaid Zafar, Muhammad Shafiq, Muhammad Azeem Rana Jun 2026

A Review On Nanoparticles: Classification And Roles In Plant Systems, Muhammad Junaid Zafar, Muhammad Shafiq, Muhammad Azeem Rana

Journal of Bioresource Management

Nanotechnology has been a new paradigm of the twenty-first century with several good breakthroughs. These tiny particles, known for their outstanding qualities, are enjoying an increasing influence in many research fields concerning foodstuff, cosmetics, electronics, and pharmacology. Synthesis of nanoparticles includes utilizing chemical processes with reducing agents, alongside employing physical techniques such as top-down and bottom-up approaches for NP formation. The biological approach, known as green synthesis, utilizes plant extracts to ensure increased safety. Biological methods also involve bacteria and fungi, known as the major sources of nanoparticles. It is acknowledged as the most effective and environmentally conscious approach, attributed …


Economic Performance And Technical Efficiency Of “Small-Scale” Vegetable Production In Ido Local Government Area Of Oyo State, Nigeria, Taiye Oluwasola Babatunde, Oluyemisi Omowunmi Babatunde Jun 2026

Economic Performance And Technical Efficiency Of “Small-Scale” Vegetable Production In Ido Local Government Area Of Oyo State, Nigeria, Taiye Oluwasola Babatunde, Oluyemisi Omowunmi Babatunde

Journal of Bioresource Management

A study was carried out to examine the economic performance of small-scale vegetable farmers and how effectively they are using their resources in Ido Local Government Area of Oyo State. The study involved eighty vegetable farmers who were chosen randomly, and information was gathered from them using structured questionnaires. Different tools such as budget analysis, linear regression, frequency distribution, percentages, and the stochastic frontier production function were used to examine the data that was collected. The results indicated that about 41.3 % of the farmers were between the ages of 41 and 50. Most of the people who answered were …


Antimicrobial Resistance Profiles And Clinical Dynamics Of Listeriosis In Small Ruminants: A One Health Review, Muhammad Aqeel, Pervez Ahmed Khoso, Amjad Hussain Mirani, Dildar Hussain Kalhoro, Abdul Ahad Soomro Jun 2026

Antimicrobial Resistance Profiles And Clinical Dynamics Of Listeriosis In Small Ruminants: A One Health Review, Muhammad Aqeel, Pervez Ahmed Khoso, Amjad Hussain Mirani, Dildar Hussain Kalhoro, Abdul Ahad Soomro

Journal of Bioresource Management

Although the incidence of listeriosis is much lower in small ruminants, it has implications for food safety, herd health and appropriate antibiotic usage as well as zoonotic potential. Both have been reported to be robust pathogens and Listeria monocytogenes is generally recognized as the most common etiologic agent, but in ovine or caprine abortion it should be included as a significant differential diagnosis. This is a narrative one health review that summarizes status of the information published to date on the epidemiology and clinical signs of infection, resistance patterns found and diagnosis and prevention methods employed in small ruminant populations. …


Endophytic Actinobacteria: Deciphering Therapeutic And Industrial Potential, And Prospects Of Genome Mining In Novel Products Discovery, Yusra Waheed, Rabia Shahdin, Imran Sajid Jun 2026

Endophytic Actinobacteria: Deciphering Therapeutic And Industrial Potential, And Prospects Of Genome Mining In Novel Products Discovery, Yusra Waheed, Rabia Shahdin, Imran Sajid

Journal of Bioresource Management

Endophytic actinobacteria are a diverse group of Gram-positive bacteria with high G+C content, which inhabit plants’ internal tissues, and represent a significant yet underexplored reservoir of bioactive secondary metabolites. In host plants, a remarkable repertoire of metabolites, including broad-spectrum antibiotics, anticancer, antiviral, antifungal, antioxidant, and immunomodulatory compounds, is synthesized by these microbial allies, carrying significant medicinal and agricultural potential. These endophytes, in contrast to their soil relatives, have developed unique biosynthetic gene clusters (BGCs) strongly influenced by plant-associated factors, leading to the production of structurally novel metabolites. In recent years, the advances in genome mining, metagenomics, and metabolomics have accelerated …


The Multifaceted Medicinal Properties Of Momordica Charantia: Insights Into Phytochemistry And Therapeutic Applications, Maham Ashfaq, Haroon Ur Rashid, Javaria Ashfaq, Shazia Ramzan, Fatma Hussain Jun 2026

The Multifaceted Medicinal Properties Of Momordica Charantia: Insights Into Phytochemistry And Therapeutic Applications, Maham Ashfaq, Haroon Ur Rashid, Javaria Ashfaq, Shazia Ramzan, Fatma Hussain

Journal of Bioresource Management

Momordica charantia (bitter melon) is a significant medicinal plant, having been long used in traditional medicine in Asian, African and South American systems. M. charantia is more than a traditional medicine; by consolidating existing evidence, it is a promising source of drug discovery and can serve as a complementary in contemporary therapeutics. Over the last several decades, it has become the subject of contemporary biomedical studies due to its abundance of phytochemicals, such as saponins, flavonoids, alkaloids, and polypeptides. These bioactive compounds present a wide range of pharmacological processes that M. charantia can be a natural solution to some of …


Metabolic Markers And Gut Microbiota In Big Cats: A Relationship Between Diet, Health And Environment, Javeria Saman, Saima Sharif, Bushra Nisar, Shagufta Naz Jun 2026

Metabolic Markers And Gut Microbiota In Big Cats: A Relationship Between Diet, Health And Environment, Javeria Saman, Saima Sharif, Bushra Nisar, Shagufta Naz

Journal of Bioresource Management

The wild animals that occupy large territories were found to adapt less easily to captive environments compared to those with small home ranges. Among big cats, captivity posed a range of challenges, with stress emerging as central factor influencing overall welfare. Transition into captive environment was shown to alter both behavior and physiological processes, largely due to changes in their natural habitat, environmental complexity and diet. Several health issues reported in big cats including alopecia, gastrointestinal issues, neuromuscular disorders such as hindquarter paralysis were associated with underlying metabolic dysregulation. Metabolic health was recognized as critical component of overall well-being, closely …


Protective Effects Of Yogurt Against Sodium Fluoride-Induced Liver Dysfunction In Rabbits, Rasool Bux, Rehana Buriro, Shamsuddin Bughio, Kashif Ali Malak, Muhammad Aqeel, Fayaz Ali, Ali Raza, Abdul Sallam Jun 2026

Protective Effects Of Yogurt Against Sodium Fluoride-Induced Liver Dysfunction In Rabbits, Rasool Bux, Rehana Buriro, Shamsuddin Bughio, Kashif Ali Malak, Muhammad Aqeel, Fayaz Ali, Ali Raza, Abdul Sallam

Journal of Bioresource Management

Fluoride (F-) is among the most important compounds that can damage hepatic tissue and increase level of ALT, ALP, Bilirubin, GGT, and decreases the albumin. Present study was conducted to explore protective role of yogurt on hepatic dysfunction induced by sodium F- at different doses. Animal were divided into seven experimental groups (6 rabbits/group). Group A (Control), Group B (F- 50 mg/kg), Group C (yogurt 15 g/kg), Group D (F- 50 mg + yogurt 15 g/kg), Group E (F- 100 mg/kg), Group F (yogurt 30 g/kg), Group G (F- 100 mg/kg B.W. + yogurt 30 g/kg). In F- treatment groups …


In Vitro Anticancer Evaluation Of Tamoxifen And Paclitaxel-Loaded Chitosan Nanoparticles Against Breast And Lung Cancer With In Silico Docking, Arshia Amaan, Farah Mehak, Amer Jamil, Fatma Hussain Jun 2026

In Vitro Anticancer Evaluation Of Tamoxifen And Paclitaxel-Loaded Chitosan Nanoparticles Against Breast And Lung Cancer With In Silico Docking, Arshia Amaan, Farah Mehak, Amer Jamil, Fatma Hussain

Journal of Bioresource Management

Breast and lung cancer are the primary cause of death worldwide, underlining the need for an improved therapeutic strategy. In the current study, tamoxifen (TAM) and paclitaxel (PTX) loaded chitosan nanoparticles (NPs) were produced for the evaluation of sustained drug delivery and enhanced anticancer potential of nanocarriers over conventional chemotherapy against breast and lung cancers, respectively. Nanoparticles were produced by the ionic gelation method and characterized by UV-visible spectroscopy, Dynamic Light Scattering and Fourier Transform Infrared Microscopy (FTIR), verifying the nanoscale morphology, stability and successful encapsulation. A drug release profile study (in vitro) (78 %, 60-75 %) and …


Liver Function Test (Lfts) Revealed Ameliorative Effect Of Probiotics And Antibiotics As Therapeutic Agents Against Experimentally Induced Enterotoxemia In Goat, Muhammad Mohsen, Jam Kashif Zaman, Amjad Hussain Mirani, Nazeer Hussain Kalhoro, Benazir Sahito Jun 2026

Liver Function Test (Lfts) Revealed Ameliorative Effect Of Probiotics And Antibiotics As Therapeutic Agents Against Experimentally Induced Enterotoxemia In Goat, Muhammad Mohsen, Jam Kashif Zaman, Amjad Hussain Mirani, Nazeer Hussain Kalhoro, Benazir Sahito

Journal of Bioresource Management

Present study was conducted to evaluate the various liver enzymes in experimentally induced enterotoxemic goat inorder to ensure the therapeutic potential of probiotics and antibiotics. Experiment was conducted at Department of Veterinary Medicine, Sindh Agriculture University Tandojam in which 35 non-descriptive goats were housed and experimenatally induced with enterotoxemia by inoculation of Clostridium perfringens culture surgically by performing laparotomy into intestine. After apperence of positive clinical signs of infection, goats were randomly divided into 5 treatment groups i.e. Group 1 (negative control), Group 2 (positive control), Group 3 (yogurt, 5 % solution, 50 mL/time), Group 4 (Yeast, 5 % solution, …


Prevalence And Risk Factors Association Of Babesiosis In Cattle And Buffaloes In District Naushahro Feroze, Sindh, Pakistan, Kazim Raza, Amjad Hussain, Sajid Moin, Huzaifa Arain, Muhammad Mohsen, Maria Abubakar, Erum Bughio, Barkat Ali Jun 2026

Prevalence And Risk Factors Association Of Babesiosis In Cattle And Buffaloes In District Naushahro Feroze, Sindh, Pakistan, Kazim Raza, Amjad Hussain, Sajid Moin, Huzaifa Arain, Muhammad Mohsen, Maria Abubakar, Erum Bughio, Barkat Ali

Journal of Bioresource Management

Background: Bovine babesiosis is a protozoan disease that is transmitted by ticks and has significant veterinary and economic impacts on tropical livestock systems. Prior to this study, no epidemiological data was available of Sindh, Pakistan.

Purpose: To estimate the Babesia spp. prevalence and estimate the risk factors with respect to cattle and buffaloes in five tehsils of District Naushahro Feroze, Sindh, Pakistan.

Methods: A cross-sectional study was conducted using 200 blood samples (100 Thari cattle; 100 Kundhi buffaloes; both sexes) in five tehsils (Kandiaro, Moro, Mehrabpur, Bhiria and Naushahro Feroze). Thin blood smears under Giemsa stain were viewed under oil-immersion …


Evaluation Of Heavy Metal And Health Risks Of Well Water In Abobo, Osara And Osaragada Communities In Kogi State, North-Central, Nigeria, Muhammed Haruna Isah, Blessing Ahmed, Dauda Tanko, Adang Kombe Lucas Jun 2026

Evaluation Of Heavy Metal And Health Risks Of Well Water In Abobo, Osara And Osaragada Communities In Kogi State, North-Central, Nigeria, Muhammed Haruna Isah, Blessing Ahmed, Dauda Tanko, Adang Kombe Lucas

Journal of Bioresource Management

Human health may be at risk if drinking water contains excessive amounts of heavy metals (HMs). To determine risks related to heavy metals, fifteen water samples were taken every month between July and September, 2024 from the communities of Abobo (Site A), Osara (Site B) and Osaragada (Site C) close to Confluence University of Science and Technology, Osara. These samples were tested for ten HMs (Cu, Fe, Ni, Zn, Co, Cd, As, Cr, Hg, Pb) with the aid of Atomic Absorption Spectroscopy. The average concentration ranges as follows: Fe (0.378-0.511 mg/l), Cu (1.643-1.720 mg/l), Ni (0.31-0.556 mg/l), Zn (0.17-0.271 mg/l), …


Isolation, Quantification, And Characterization Of Microplastics In Atmospheric Fallout Across Different Areas Of Lahore, Punjab, Pakistan, Muhammad Rizwan, Aqib Javed, Muhammad Javed Islam, Kashif Riaz, Asif Bilal, Muhammad Nasir, Ayesha Ali Jun 2026

Isolation, Quantification, And Characterization Of Microplastics In Atmospheric Fallout Across Different Areas Of Lahore, Punjab, Pakistan, Muhammad Rizwan, Aqib Javed, Muhammad Javed Islam, Kashif Riaz, Asif Bilal, Muhammad Nasir, Ayesha Ali

Journal of Bioresource Management

Microplastics have become widely dispersed in our environment, and even in the air we breathe. The present research aims at identifying and determining the amounts of microplastics present in atmospheric fallout over Lahore city, which is characterized by a large population and several manufacturing industries. In order to find out the existence of microplastics, samples of atmospheric fallout were collected from various sites across hustling municipalities of Lahore that included urbanized settlements. The analysis disclosed that there are various forms of microplastic fibers, fragments and granules indicating different sources of pollution. The identified ones varied from 114.485 µm to 2034.731 …