Life Sciences Commons^™

Fluorescence Probes For Bioimaging: Synthesis, Photophysical Properties And Applications, Mehrun Nahar Uddin

Dissertations

Fluorescent probes are a vital tool in the study of cell imaging. There are many types of fluorescent probes ranging from inorganic and organic nanoparticles to organic molecules. When used judiciously, they can help provide essential information on cellular structure and function. The introduction of two-photon microscopy has expanded the need for new probes, in particular near-infrared (NIR) absorbing and emitting fluorescent probes. The photochemical and photophysical properties of NIR probes play a crucial role in their effectiveness in cell imaging by both conventional and two-photon excitation (2PE) microscopy. In this research, the synthesis, photophysical properties, and two-photon absorption (2PA) …

Bodipy Based Photodynamic Therapy And Potassium Probes, Xiangshan Liu

Dissertations

Boron dipyrromethene (BODIPY) has become more and more popular in photophysical and biological applications. BODIPY based fluorescence compounds have numerous advantage properties including low toxicity, high absorption extinction coefficients, high fluorescence quantum yields, sharp fluorescence emissions, and resistance to photobleaching. All the good properties lead to the wide applications of BODIPY based compounds. In this research, two different kinds of BODIPY are synthesized. Firstly, BDBrC containing carbazole and BODIPY core is synthesized. Cellular uptake research shows BDBrC can target on lysosome and singlet oxygen generation research result indicates that BDBrC can be used in photodynamic therapy. BDBrC also shows pH-sensitive …

Forecasting Locational Marginal Prices In Electricity Markets By Using Artificial Neural Networks, Kim Jay R. Rosano, Allan C. Nerves

Journal of Economics, Management and Agricultural Development

Electricity price forecasting is an important tool used by market players in decision-making and strategizing their participation in the electricity market. In most studies, market-clearing price is forecasted as it gives an aggregated overview of system price. However, locational marginal price (LMP) gives better outlook of the price particular to the customer location in the electrical power grid. This study utilizes Artificial Neural Networks to forecast weekday LMP of generator and load nodes. Various inputs such as historical prices and demand, and temporal indices were used. Using data for selected nodes of the Philippine Wholesale Electricity Spot Market, forecast Mean …

Analisis Biomekanika Free Throw Basket Sesuai Kaidah Dave Hopla, Fajar Awang Irawan, Wisnu Kerta Raharja, Tafriyadhur Risa Billah, Mirza Arif Ma'dum

Jurnal Keolahragaan

Penelitian ini bertujuan untuk menganalisis gerakan free throw sesuai dengan kaidah Dave Hopla. Metode penelitian ini menggunakan eksperimen dengan teknik tes dan pengukuran. Total sampel berjumlah 5 atlet PPLP Basket Kota Semarang yang telah mengisi inform consent dan menyetujui prosedur penelitian. Hasil penelitian ini didapatkan rata rata waktu pada tahap persiapan sebesar 0,53 ± 0,13 detik dengan sudut ayunan sebesar 120°. Gerakan awalan sudut lengan 90° dan rata rata waktu 0,25 ± 0,04 detik dengan sudut fleksi lutut sebesar 99,04 ± 0,04 derajat. Data pada tahap pelaksanaan untuk waktu yang diperoleh sebesar 0,29 ± 0,07 detik dengan sudut fleksi lengan …

The Effect Of Skipping Combination With Body Weight Training On Cardiorespiratory Endurance And Body Mass Index (Bmi) As A Covid-19 Prevention Effort For Overweight Adolescents, Ahmad Nasrulloh, Rina Yuniana, Kukuh Wahyudin Pratama

Jurnal Keolahragaan

This study aims to determine the effect of skipping combination with body weight training on cardiorespiratory endurance and BMI as an effort to prevent Covid 19 for overweight adolescents. This research is an experimental research. In this study, treatment was given in the form of skipping exercise combined with body weight training for 8 weeks with a frequency of 3 times / week, an intensity of 60%-70% MHR with a duration of 30 minutes. The population in this study were teenagers. Sampling was done by purposive sampling on adolescents aged between 17-21 years and overweight. Instrument used to measure VO2 …

The Effect Of Brain Vitalization Exercise On Muscle Strength And Endurance In People With Dementia, Mustika Fitri, Ajeng Fauziyah, Hana Astria Nur

Jurnal Keolahragaan

This study aims to determine the effect of brain vitalization exercise on muscle strength and endurance in people with dementia. The pre-experimental method with a one-group pretest-posttest design was used in this study. Purposive sampling technique was used in this study, then a sample of 31 people with dementia was obtained from a population of 78 people in Cibeunying Kidul District. The Arm Curl Test instrument is used in research that aims to measure arm muscle strength and Chair Stand Test which aims to measure leg muscle endurance. The data analysis technique in this study used Paired Sample T Test …

Pengembangan Instrumen Tes Dribbling Pada Permainan Futsal Menggunakan Teknologi Mikrokontroler Arduino, Randy Febri Tauba, Bafirman Hb

Jurnal Keolahragaan

Penelitian ini bertujuan untuk membuat prototipe instrumen tes dribbling futsal menggunakan teknologi mikrokontroler arduino yang terhubung dengan aplikasi android. Penelitian ini merupakan penelitian dan pengembangan (Research and Development). Subjek penelitian adalah Pemain Futsal SMA N 1, 2 dan 9 Sijunjung, Kecamatan Sijunjung, Kabupaten Sijunjung, Sumatera Barat. Untuk Validasi alat oleh tiga orang ahli yaitu ahli Evaluasi dan Tes Pengukuran, Ahli Futsal, dan Ahli IT. Pengembangan instrumen tes dribbling futsal ini dilakukan dengan uji kelompok kecil dengan sampel 15 orang putra dan uji kelompok besar dengan sampel 45 orang putra. Metode yang digunakan adalah metode validitas ahli dengan penilaian menggunakan instrumen …

Teknik Yang Paling Dominan Pada Pertandingan Futsal Putra Profesional, I Dewa Made Aryananda Wijaya Kusuma

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui teknik yang paling dominan digunakan pada pertandingan futsal putra profesional. Penelitian ini termasuk pada jenis kuantitatif dengan metode survei. Sampel yang digunakan berjumlah empat tim liga futsal putra profesional dengan teknik pengambilan sampel yang digunakan adalah purposive sampling. Analisis data menggunakan uji frekuensi dan presentase dari teknik yang paling sering digunakan. Hasil dari penelitian ini menunjukkan bahwa frekuensi penggunaan teknik passing sebanyak 2181 kali, control sebanyak 1853 kali, dribbling sebanyak 422 kali, shooting sebanyak 238 kali, feinting sebanyak 92 kali, heading sebanyak 25 kali, shielding sebanyak 56 kali, turning sebanyak 17 kali, dan chipping sebanyak …

The Effect Of Uphill And Downhill Exercise On Soccer Player's Leg Power, Stanis Krisyanto, Hari Amirullah Rachman

Jurnal Keolahragaan

The uphill and downhill training method is one of the exercises that must be applied because it is an important component in the success of the soccer game. The objectives were to examine (1) the difference in the effect of uphill and downhill training on leg power, (2) the difference between players with high and low leg strength on leg power; and (3) the interaction between uphill and downhill training with leg strength (high and low) on leg power of football players. This type of research is an experiment with 2 x 2 factorial. The sample of Sleman United football …

The Effect Of Drill Exercise And Reaction Speed On The Drive Accuracy Of Beginner Table Tennis Athletes, Suisdareni Suisdareni, Tomoliyus Tomoliyus

Jurnal Keolahragaan

This study aimed to test (1) the differences of drill practice effect of a constant set of rising repetition and rising set of repetition continually on drive accuracy (forehand and backhand drive) for the beginner table tennis athletes, (2) the differences of the effect of high and low reaction speed on the drive accuracy (forehand and backhand drive) for the beginner table tennis athletes in Yogyakarta, and (3) the relation between drill practice and reaction speed on improving the drive accuracy (forehand and backhand drive) for the beginner table tennis athletes in Yogyakarta. This research used an experiment with a …

Reevaluation Of The Described Subspecies Of Euphydryas Phaeton (Drury, 1773) With A Replacement Name For Melitaea Phaeton Schausi (Clark, 1927), Harry Pavulaan

The Taxonomic Report of the International Lepidoptera Survey

The present paper reevaluates the subspecific standing of the nominotypical and three described subspecies of Euphydryas phaeton (Drury, 1773). The nominotypical subspecies phaeton occupies the mid-Atlantic region, with undefined zones of contact with described subspecies borealis (F. Chermock & R. Chermock, 1940) to the north, and subspecies schausi (Clark, 1927) to the south. Nominotypical phaeton is an intermediate phenotype between borealis and schausi, which are each noticeably different from each other but both reasonably similar to intermediate (nominotypical) phaeton. Both borealis and schausi were synonymized under nominotypical phaeton since about time of their descriptions, by authors and list …

Nesting Behavior, Ecology, And Functional Morphology Of The Trapdoor Spider-Hunting Spider Wasp Aporus (Plectraporus) Hirsutus (Banks) (Hymenoptera: Pompilidae), Frank E. Kurczewski, Alice J. Abela, Rick C. West

Insecta Mundi

Macrophotographs in series taken by Alice Abela on sandy coastal dunes in Santa Barbara and San Luis Obispo Counties, CA in 2010–2021 supplement and enhance F. X. Williams (1928) study of the ecol­ogy and nesting behavior of the trapdoor spider-hunting spider wasp Aporus (Plectraporus) hirsutus (Banks) (Hymenoptera: Pompilidae: Aporini). Abela’s macrophotographs and observations provide new details of adult wasp feeding, functional morphology, hunting, digging and prey transport, and host spider trapdoor, entrance, burrow structure, host capture and escape activity. Newly reported host records from this study and online photographs expand A. hirsutus host selection in the large wafer-lid …

Micromentignatha Geberti, A New Tiger Beetle Species From Australia (Coleoptera: Cicindelidae), Jürgen Wiesner

Insecta Mundi

Micromentignatha geberti (Coleoptera: Cicindelidae), new species, is described. It is distinguished from the other members of the genus by its larger body size and shape of elytral maculation.

Due to the kindness of Christian Kerkering, I was able to study specimens of a tiger beetle species he recently acquired. It proved to be new to science and is described herein. It is a member of Micromentignatha Sumlin, 1981, which raises the number of species in this genus to four (Wiesner 2020: 327). A key to distinguish these congeners as well as a catalog of the genus are given herein.

Ishtarella Thailandica Martens, New Genus, New Species (Hymenoptera: Braconidae: Aphidiinae) Of Aphid Parasitoid From Thailand, With A Country Checklist Of Aphidiinae, Abigail P. Martens, Matthew L. Buffington, Donald L.J. Quicke, Marisa Raweearamwong, Buntika A. Butcher, Paul J. Johnson

Insecta Mundi

Ishtarella Martens new genus (Hymenoptera: Braconidae: Aphidiinae) and I. thailandica Martens new species are described and illustrated from Doi Phu Kha National Park, Nan Province, Thailand. The genus is assigned to the tribe Aphidiini, subtribe Trioxina. Based on morphology, Ishtarella appears most closely related to Binodoxys Mackauer. An updated checklist of the aphidiine fauna of Thailand, based on published records, is presented.

Parasitoid wasps in the subfamily Aphidiinae (Hymenoptera: Braconidae) comprise about 60 genera and more than 650 species worldwide (Yu et al. 2016). The Aphidiinae of Thailand were all but unknown prior to a Thai­land Inventory Group for Entomological …

Ardella Magnaemirabilis (Coleoptera: Scarabaeidae: Melolonthinae: Ardellini), A New Scarabaeoid Species, Genus And Tribe From The Southwestern United States, M. J. Paulsen

Insecta Mundi

An interesting new taxon of scarabaeoid beetle is described from western Texas, USA. The remark­ably small chafer, Ardella magnaemirabilis new genus, new species (Coleoptera: Scarabaeidae: Melolonthinae: Ardellini) is described and compared to other diminutive scarabaeoid genera from drier habitats of the southwestern USA. The tribe Ardellini, new tribe, is erected to accommodate the unusual genus.

After a few centuries with entomologists scouring the continent, the discovery of unknown Nearctic scarab gen­era is no longer commonplace. The western United States, in particular, is biogeographically diverse with pockets of endemism that makes such discoveries still possible, driving collectors to continue sampling …

Usf Jamovi Tutorial Project: Open Education Resource, Aline Hitti, Saera Khan

USF OER Faculty Grant Projects

Jamovi is an open source free software that USF staff, faculty and student can download to carry out any statistical analyses. The current report summarizes the progress made on an Open Education Resource Grant funded project, which aimed to created Jamovi tutorials. In this report, student feedback and faculty reaction are summarized after one semester of using the tutorials created.

Biologic Tnf-Α Inhibitors Reduce Microgliosis, Neuronal Loss, And Tau Phosphorylation In A Transgenic Mouse Model Of Tauopathy, Weijun Ou, Joshua Yang, Juste Simanauskaite, Matthew Choi, Demi M. Castellanos, Rudy Chang, Jiahong Sun, Nataraj Jagadeesan, Karen D. Parfitt, David H. Cribbs, Rachita K. Sumbria

Pharmacy Faculty Articles and Research

Background

Tumor necrosis factor-α (TNF-α) plays a central role in Alzheimer’s disease (AD) pathology, making biologic TNF-α inhibitors (TNFIs), including etanercept, viable therapeutics for AD. The protective effects of biologic TNFIs on AD hallmark pathology (Aβ deposition and tau pathology) have been demonstrated. However, the effects of biologic TNFIs on Aβ-independent tau pathology have not been reported. Existing biologic TNFIs do not cross the blood–brain barrier (BBB), therefore we engineered a BBB-penetrating biologic TNFI by fusing the extracellular domain of the type-II human TNF-α receptor (TNFR) to a transferrin receptor antibody (TfRMAb) that ferries the TNFR into the brain via …

The Benefits Of Astaxanthin To Improve Pain Relief In Patients With Painful Diabetic Neuropathy: An Open-Label, Randomized Controlled Trial, Rizaldy Taslim Pinzon, Mary Rose Angelina Budi Harsana

Pharmaceutical Sciences and Research

Treatment of diabetic neuropathy is still carried out by providing symptomatic therapy, which only improves ± 50% of the total symptoms felt by patients, but does not tackle the underlying causes of the disease. Astaxanthin is a potent antioxidant, anti-inflammatory, and anti-diabetic carotenoid that could be an additional treatment option. We aimed to measure the effectiveness of administering astaxanthin as an additional therapy to improve the impact of pain and discomfort experienced daily by diabetes mellitus patients with painful diabetic neuropathy. We conducted a randomized experimental study with an open label design of 36 patients who had been diagnosed with …

Comparative Analytical Study Of Phytochemicals In Selected Antidiabetic Medicinal Plant Seeds In Sri Lanka, Gowri Rajkumar, Mihiri Rangika Jayasinghe, Vinotha Sanmugarajah

Pharmaceutical Sciences and Research

Medicinal plants are universally used in the management of various diseases in different medical practices. A varied diversity of compounds extracted from plants may show anticancer, antibacterial, and antidiabetic activities. Comparative laboratory studies and scientific approach of efficacy related to phytochemicals found in medicinal plants in Sri Lanka have not been reported yet. This study aims to evaluate the phytochemicals in selected four different plant seeds such as Syzygium cumini (L.) Skeels, Brassica alba (L.) Rabenh, Trigonella foenum-graecum L. and Nigella sativa L., which are used in the management of diabetes mellitus in Sri Lanka. The ethanol extracts of …

Community Participation On Waste Bank To Facilitate Sustainable Solid Waste Management In A Village, Indriyani Rachman, Nia Komalasari, Ira Rumiris Hutagalung

Journal of Environmental Science and Sustainable Development

Community participation is required for managing solid waste. In Indonesia, community acceptance and participation in solid waste management are assessed by the presence of a waste bank at the village or neighborhood level. This study aimed to find out the source, economic potency, and handling system of solid waste in a village setting. This study took place at Ketapang Village, Mauk Sub District, Tangerang Regency, Indonesia. This study evaluated the community participation in the waste bank in Ketapang Village, which is called, Sakumis Bersalaman Waste Bank, and its potential to manage solid waste and generate some profits for …

Valorisation Of The Effects Of Bioactive Compounds Of The Ethanolic Extract Of Ramalina Farinacea (Ramalinaceae) On The Development, Eating And Pupation Behavior Of Drosophila Melanogaster (Diptera: Drosophilidae), Fatma Zohra Saadane, Nour El Imene Boublata, Sarra Habbachi, Abir Bouzar, Waffa Habbachi, Abderachid Slimani, Abdelkrim Tahraoui

Journal of Bioresource Management

Plants are rich in bioactive chemical secondary metabolites and have proven insecticidal activity by killing or repelling insects. In this work, we aim to evaluate the direct and delayed effects of ethanolic plant extracts on the vinegar fly (Drosophila melanogaster). The treatment was performed by ingestion on second instar larvae (L2) to evaluate the impact of the ethanolic extract on development for 15 days and subsequently on the feeding behavior of the larvae. The results of this study indicate a slowing down of pupal growth until the adult stage, at the three concentrations (0.25 µg/ml, 0.5 µg/ml, 1.5 …

Biodiversity Of The Blattopteran Fauna In The Chelia Cedar Forest (The Aures - Eastern Algeria), Nadia Aberkane, Sarra Habbachi, Wafa Habbachi, Nora Belkhiri, Naama Frah

Journal of Bioresource Management

The cedar forests in Algeria represent a model of forests very rich in entomological fauna and especially dictyopterans, notably blattopterans. In the cedar forest of Chelia in the Aurès Mountains, we chose three different sites according to altitude (2020 m, 1920 m, 1820 m) in order to collect existing cockroaches using the sight-hunting method (twice a month). The inventory allowed us to capture more than 1220 cockroaches and we were able to identify three genus (Dziriblatta, Phyllodromica ,Loboptera) and seven species: Dziriblatta stenoptera, Dziriblatta nigrivintris, Phyllodromica zebra, Pyllodromica trivittata, Phyllodromica sp, Loboptera angulata, Loboptera alluaudi, of which …

Structure And Parasitism Of Egg-Batches Of The Pine Processionary Moth, Thaumetopoea Pityocampa In The Algerian Cedar Forests., Zineb Messaadia, Nabil Bertella, Naama Frah

Journal of Bioresource Management

Today, climate change is one of the greatest threats facing forest ecosystems. It directly influences the geographical distribution of insects and increases epidemics of harmful insects. The present work took place in this context. It aimed to contribute to the knowledge of egg parasitoids that could affect the evolution of the pine processionary caterpillar Thaumetopoea pityocampa, a major forest pest in Algeria and Mediterranean countries. The study was carried out on 120 batches of eggs taken from the Atlas cedar at two sites in the Chelia cedar zone (case of eastern Algeria) in 2017. It allowed the analysis of a …

Composition, Population Structure And Regeneration Potential Of Tree Species In Oak-Dominated Mixed Forests Of Rajouri District In Jammu And Kashmir, India, Mohd Junaid Jazib, Javed Manzoor

Journal of Bioresource Management

The study was carried out to explore the diversity and regeneration potential of trees species in mixed Oak forest of Rajouri district of Jammu and Kashmir (India). A total of 20 tree species were recorded from the area dominated by various species of oak particularly Quercus leuchotrichophora. Quercus leuchotrichophora shows maximum values of density, basal cover and IVI. In different localities, it has different groups of associates like Q. floribunda, Q. semecarpifolia, Q. glauca, Buxux wallichiana, Pinus roxburghii, Aesculus indica, Rhododendron arboreum, etc. Majority of the species show very poor regeneration and thus demands for immediate implementation of appropriate conservation …

Evaluation Of The Toxic Effects Of Aqueous Extracts Of Solanum Nigrum L.( Solanaceae ) On The Mortality And Development Of Drosophila Melanogaster (Diptera : Drosophilidae)., Makarem Rahat, Sara Habbachi, Ibtissem Samai, Wafa Habbachi, Abir Bouzar, Saliha Benhissen, Abdelkrim Tahraoui

Journal of Bioresource Management

Solanum nigrum is a plant that has therapeutic properties of the Solanaceae family. It is used extensively in traditional medicine but also as a bio-insecticide to control insect pests. Some parts of this plant can be very toxic to livestock and humans. In the present study, the direct and delayed toxic effects of aqueous extracts of S. nigrum on the mortality and development of Drosophila melanogaster were investigated. For this study, an extraction method including decoction is adopted to extract the active principles from the leaves of S. nigrum. The treatment was carried out by ingestion on 2nd instar …

The Impact Of Socioeconomic Factors On Public Health Care Expenditure In Asean Countries, Hui Nee Au Yong, Yi Ling Chong, Qi Hui Ng, Jen Hee Tan, Yuan Yuan Tay

Journal of Environmental Science and Sustainable Development

This study focuses on the macroeconomic, environmental, and socioeconomic determinants that would bring an impact on the healthcare. The ASEAN countries' economic growth, carbon emissions, urban population, and energy consumption are hypothesized to be correlated with healthcare expenditure. This study aims to investigate the impact of each factor affecting healthcare expenditure in these six ASEAN countries. The study looks into six ASEAN countries, i.e. Indonesia, Philippines, Thailand, Malaysia, Singapore, and Brunei Darussalam for the period of 2010-2014. A panel data analysis was conducted to meet the objectives of this study. To test the stationarity of the data, panel unit root …

Optical And Chemical Properties Of Fragaria Ananassa And Galena: Potential Photosensitizers In A Natural Dye-Sensitized Solar Cell, Ibukun S Akinsola, Aderemi B Alabi, Coppede Nicola

Tanzania Journal of Science

Dye is one of the major components for high power conversion efficiency in a dye-sensitized solar cell. There are challenges natural dyes encounter, especially with quick degradation of the dye molecules. This work considered mineral dye in comparison with plant dye to address the challenge of degradation of natural plant dyes. The optical properties and functional groups of the two natural dyes were studied in this work. The absorption spectra, the optical band gaps and the absorption coefficients of the dyes were reported and found to be suitable for use as photosensitizers in a dye-sensitized solar cell (DSSC), as they …

Effects Of Copper Fungicides Spray On Nutrient Contents In Soils Of Cocoa Growing Areas Of Southwestern Nigeria, Musibau O Azeez, Olusola O Adesanwo, Joseph A Adepetu

Tanzania Journal of Science

The present study aimed at evaluating the effects of copper fungicides spray on physical and chemical properties of soils of cocoa growing areas of southwestern Nigeria. Samples were collected from selected cocoa farms and adjacent plots across three states (9 samples from Osun State, 9 samples from Ondo State and 7 samples from Ekiti State), within rainforest zone of Nigeria. The physical and chemical properties of the soil samples were determined. Copper contents of the cocoa plantation soils were significantly higher (16.23 mg Cu/kg) than the adjacent plots (6.31 mg Cu/kg) indicating accumulation of Cu in the soil because of …

Physico-Chemical Properties Of Mechanically Extracted Banana Juice At Different Ripening Stages, Mathayo G Mathias, Lilian D Kaale, Oscar Kibazohi

Tanzania Journal of Science

This paper presents the findings of a study on physico-chemical properties of low viscosity banana juice from five banana cultivars: Pisang Awak (PSA) an ABB genome, Yangambi km5 (YKM5) an AAA genome and cultivars from AAA-EA genome, namely Mbilabile, Ndeshi and Mlonga. Low viscosity banana juice was extracted using improved mechanical method at five ripening stages. The physico-chemical properties significantly varied according to cultivars and ripening stages (p < 0.05). Yields, total soluble solids (TSS), titratable acidity (TA) and pH were in the range of 19.50–74.03%, 7.33–27.64 ºBrix, 0.37–0.76% malic acid equivalent and 4.09–4.70, respectively. Yields decreased in the order of Mbilabile > Ndeshi > Mlonga > YKM5 > PSA whereas the total soluble solids increased as follows Mlonga < Mbilabile < Ndeshi < YKM5 < PSA. Furthermore, ashes and mineral contents decreased with ripening stages whereas the low viscosity banana juice was rich in potassium and magnesium. Finally, the study recommends stage 5 of the ripeness as ideal for producing low viscosity banana juice. Keywords: Mechanical extraction, Banana cultivar, Ripening stage, Tannin, Banana juice.

Placental Insulin-Like Growth Factor-1 Receptor, Protein Kinase B And Mammalian Target Of Rapamycin Are Downregulated In Hiv-1 Positive Women On Antiretroviral Drugs, Winifrida B. Kidima, Gatambwa D. Mukandala, Osiana Leonard, Daniel Nkungu

Tanzania Journal of Science

HIV-1 and ARV drugs uptake during pregnancy may change placental phenotype during pregnancy affecting fetal growth. We investigated the influence of maternal HIV-1 and ARV drugs on expression of placental genes important for fetus growth. A total 51 HIV-1 positives and 46 HIV-1 negative pregnant women were studied. Placental gene expression changes of insulin-like growth factor receptor 1 (IGF-1) R, mammalian target of rapamycin (mTOR), protein kinase B (AKT-1), sodium-coupled neutral amino acid transporters (Slc38a1, Slca38a2, Slc38a4), inhibin A, adrenomedullin and 11 beta-Hydroxysteroid dehydrogenase type (HSD)-2 were assessed by RT-qPCR. There was a significant decrease in mRNA expression of placental …