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Articles 54601 - 54630 of 256009
Full-Text Articles in Life Sciences
The Planted Catalog: The Role Of The Botanical Garden In Botany, Douglas Tuers
The Planted Catalog: The Role Of The Botanical Garden In Botany, Douglas Tuers
Journal of the South Carolina Academy of Science
This article will investigate the role of the botanical garden in botany. What its role is and how it fills it. This article will take the Missouri Botanical Garden as a case study, drawing heavily from archival material compromised mostly of letters between Henry Shaw and the prominent botanists of his day. This study also draws on the prominent histories of the Missouri Botanical Garden. The analysis use the philosophical tradition around reference in logic and language. This study argues that the botanical garden is a bridge between locality and herbaria. The order of the flora travels to the locality …
Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti
Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti
Journal of the South Carolina Academy of Science
An intermolecular Friedel-Crafts alkylation of indole and tertiary allylic alcohols has been developed. The allylic alcohols were synthesized using a two-step procedure, then exposure of these alcohols to diphenyl phosphate facilitated the desired annulation reaction. This reaction tolerated a variety of indole substitutions to yield 1H,2H,3H,4H-pyrido[1,2-a]indoles.
Women In Stem Fellowship: An Intersectional And Interdisciplinary Approach To Advancing Inclusion In The Sciences, Ina C. Seethaler, Gabriela Perez-Alvarado
Women In Stem Fellowship: An Intersectional And Interdisciplinary Approach To Advancing Inclusion In The Sciences, Ina C. Seethaler, Gabriela Perez-Alvarado
Journal of the South Carolina Academy of Science
At our university, women-identified individuals make up 23% of students in STEM fields; less than 15% of them graduate with a STEM degree. Nationally, more than 40% of women who enter a STEM job leave it within fewer than ten years. Gendered issues within STEM industries have been identified, yet we are far from equal opportunities for all genders. In 2018, we—the director of Women’s and Gender Studies (WGS) with colleagues in Math, Computing Sciences, and Chemistry—received a $45,000 grant to create a “Women in STEM Fellowship.” The inclusion of WGS made the fellowship interdisciplinary, intersectional, and informed our decision-making …
Human Papillomavirus Associated Prevention: Knowledge, Attitudes, And Perceived Risks Among Men Who Have Sex With Men And Transgender Women In Pakistan: A Qualitative Study, Muslima Ejaz, Anna Mia Ekström, Alyan Ahmed, Aymen Haroon, Dania Ali, Tazeen Saeed Ali, Mariano Salazar
Human Papillomavirus Associated Prevention: Knowledge, Attitudes, And Perceived Risks Among Men Who Have Sex With Men And Transgender Women In Pakistan: A Qualitative Study, Muslima Ejaz, Anna Mia Ekström, Alyan Ahmed, Aymen Haroon, Dania Ali, Tazeen Saeed Ali, Mariano Salazar
Community Health Sciences
Objectives: Men who have sex with men (MSM) and transgender individuals are at higher risk of genital warts and anal cancer due to sexually transmitted human papillomavirus infection. This study explores MSM and transgender women's perceptions of Human papillomavirus (HPV) infection and HPV prevention strategies (screening and vaccination) in Pakistan.
Design: A qualitative study using focus group discussions (FGD) with self-identified MSM, male sex workers and transgender women were conducted between March 2019 to August 2019 in Karachi, Pakistan.
Methods: Participants were recruited from community-based organization (CBO) working for MSM and transgender women. A total of 38 men and 10 …
Factors Contributing To Bee Decline, Ann Mull, Jaydee Gunnell, Sheriden M. Hansen, Ricardo Ramirez, Andree' Walker Bravo, Cody Zesiger, Lori R. Spears
Factors Contributing To Bee Decline, Ann Mull, Jaydee Gunnell, Sheriden M. Hansen, Ricardo Ramirez, Andree' Walker Bravo, Cody Zesiger, Lori R. Spears
All Current Publications
Bees provide an important ecosystem service by contributing to the pollination of crop and wild plant species. Many factors have been attributed to bee declines, including habitat loss, improper apiary management, pesticide usage, climate change, pests and pathogens, competition among native and introduced bee species, poor nutrition, and other factors (Koh et al., 2016; Goulson et al., 2015; Graves et al., 2020; Soroye et al., 2020). Acting together, these factors intensify the pressure for survival beyond the adaptability of many species. This fact sheet reviews the factors contributing to decline in bee populations and what can be done to protect …
Safety And Activity Of Pembrolizumab In Combination With Rituximab In Relapsed Or Refractory Follicular Lymphoma, Loretta J Nastoupil, Collin K Chin, Jason R Westin, Nathan H Fowler, Felipe Samaniego, Man Chun John Ma, Fuliang Chu, Ly Dsouza, Chizobam Obi, Jennifer Mims, Lei Feng, Shouhao Zhou, Michael Green, Richard Eric Davis, Sattva S Neelapu
Safety And Activity Of Pembrolizumab In Combination With Rituximab In Relapsed Or Refractory Follicular Lymphoma, Loretta J Nastoupil, Collin K Chin, Jason R Westin, Nathan H Fowler, Felipe Samaniego, Man Chun John Ma, Fuliang Chu, Ly Dsouza, Chizobam Obi, Jennifer Mims, Lei Feng, Shouhao Zhou, Michael Green, Richard Eric Davis, Sattva S Neelapu
Faculty, Staff and Student Publications
PD-1 blockade enhances the function of antitumor T cells and antibody-dependent, cell-mediated cytotoxicity (ADCC) of NK cells. In a single-center, open-label, phase 2 trial, we tested the combination of pembrolizumab, an anti-PD-1 monoclonal antibody, and rituximab, an anti-CD20 monoclonal antibody that induces ADCC, in 30 patients with follicular lymphoma (FL) with rituximab-sensitive disease who had relapsed after ≥1 prior therapy. Pembrolizumab was administered at 200 mg IV every 3 weeks for up to 16 cycles, and rituximab was given at 375 mg/m2 IV weekly for 4 weeks in cycle 1 only. The most common grade 3/4 adverse events (AEs) were …
Livestock Farmers And Researchers Perceptions About Ecosystem Services Provided By Rio De La Plata Grasslands, Daniela Schossler, Carlos Nabinger, Pablo Boggiano, Diana L. Restrepo-Osorio, Claudio Ribeiro
Livestock Farmers And Researchers Perceptions About Ecosystem Services Provided By Rio De La Plata Grasslands, Daniela Schossler, Carlos Nabinger, Pablo Boggiano, Diana L. Restrepo-Osorio, Claudio Ribeiro
IGC Proceedings (1977-2023)
The perception and valuation that livestock farmers have about ecosystem services provided by natural pastures is of fundamental importance to their management decisions and the conservation of this resource. This work aims to reveal results of a project carried out in Brazil, Paraguay, Argentina and Uruguay using the TESSA (Toolkit for Ecosystem Service Site-based Assessment) methodology to compare the perceptions of different ecosystem services among livestock farmers and researchers. The methodology was participatory workshops, two by country, one with livestock farmers participating in the Grassland Alliance (at least 50% of natural grassland in the livestock production system) and another with …
Factors Influencing Adoption Of Rangeland Rehabilitation Technologies By Agro-Pastoralists In The Arabian Peninsula: Evidence From Analysis In Saudi Arabia And Qatar, Boubaker Dhehibi, Arash Nejatian, Abdul Aziz Niane, Azaiez Ouled Belgacem
Factors Influencing Adoption Of Rangeland Rehabilitation Technologies By Agro-Pastoralists In The Arabian Peninsula: Evidence From Analysis In Saudi Arabia And Qatar, Boubaker Dhehibi, Arash Nejatian, Abdul Aziz Niane, Azaiez Ouled Belgacem
IGC Proceedings (1977-2023)
Rangelands are the main land use in the Arabian Peninsula and cover about 50% of total area. They are under continuous heavy grazing pressure due to underlying social and economic causes as well as institutional effects. ICARDA in collaboration with the National Agricultural Research Systems (NARS) has developed and introduced different rehabilitation techniques including resting, planting native range species and water harvesting in different countries of the AP such as Kuwait, Qatar, Saudi Arabia (KSA) and Yemen. However, the adoption of these techniques by end users was not evaluated. In this context, a research has been conducted in Saudi Arabia …
Effectively Reaching The Equine Community In Kentucky, S. L. Musen, Krista L. Lea, S. Ray Smith, R. J. Coleman
Effectively Reaching The Equine Community In Kentucky, S. L. Musen, Krista L. Lea, S. Ray Smith, R. J. Coleman
IGC Proceedings (1977-2023)
Since 2009, Extension Specialists and County Extension Agents from the University of Kentucky in the Southeast United States have conducted an annual educational event; the Kentucky Equine Farm and Facilities Expo field-day. These annual field-days have provided practical, hands-on demonstrations and seminars for 135-250 members of the equine community per event. Participants have been a mix of horse owners in relation to farm size, number of horses and business vs. recreation. Many participants have not been previous consumers of Extension educational programming. One of the major draws of the Farm and Facility Expo field days has been the host sites, …
Study Of Pore Length And Chemical Composition Of Charcoal That Results From The Pyrolysis Of Coconut Shell In Bolaang Mongondow, Sulawesi, Indonesia, Meytij Jeanne Rampe, Ignatius Rachmat S. Santoso, Henny Lieke Rampe, Vistarani Arini Tiwow, Tresia Eti Ayuningsi Rorano
Study Of Pore Length And Chemical Composition Of Charcoal That Results From The Pyrolysis Of Coconut Shell In Bolaang Mongondow, Sulawesi, Indonesia, Meytij Jeanne Rampe, Ignatius Rachmat S. Santoso, Henny Lieke Rampe, Vistarani Arini Tiwow, Tresia Eti Ayuningsi Rorano
Karbala International Journal of Modern Science
Charcoal of coconut shell is produced by pyrolysis at 300oC and chemically activated using HCl. Both pyrolysis charcoal and chemical activation were measured and analyzed by Fourier Transform Infrared (FTIR), Scanning Electron Microscopy (SEM), and Energy Dispersive Spectroscopy (EDS). The functional groups found O-H, aliphatic C-H, aromatic C=C, C-O, and aromatic C-H. The distribution of pyrolysis charcoal pore length and chemical activation increased from 362 nm-1.02 µm to 1.10 µm-1.52 µm. The composition of carbon elements in the mass % of pyrolysis charcoal and chemical activation increased from 86.11% to 88.93%.
In-Vitro Evaluation Of High Dosage Of Curcumin Encapsulation In Palm-Oil-In-Water, Nanoemulsion Stabilized With A Sonochemical Approach, Uday Dasharath Bagale Phd, Aram Tsaturov, Irina Potoroko, Shital Potdar, Shirish Sonawane Phd
In-Vitro Evaluation Of High Dosage Of Curcumin Encapsulation In Palm-Oil-In-Water, Nanoemulsion Stabilized With A Sonochemical Approach, Uday Dasharath Bagale Phd, Aram Tsaturov, Irina Potoroko, Shital Potdar, Shirish Sonawane Phd
Karbala International Journal of Modern Science
Curcumin is unstable under different environmental conditions. To increase the bioavailability and stability of curcumin, it is proposed in the present study to encapsulate it in palm oil-in-water nanoemulsions using ultrasound. The present work deals with maximum curcumin encapsulation into oil forms stable nanoemulsion using a food-grade surfactant and examines its antioxidant assay and in-vitro study. The synthesized curcumin nanoemulsion (CuNE) shows particle size in the range of 14.7 ± 3 nm, 95 ± 0.5% encapsulation efficiency, and provides stability against different environmental parameters. Furthermore, in-vitro analysis of high dosage CuNE shows more than 80-90% retention during simulated gastric and …
Application Of The Tessa Methodology In A Pilot Protocol For Participatory Evaluation Of Ecosystem Services And Agents Of Change In The Pampa Grasslands. Method Description And Lessons Learned, Daniela Schossler, Carlos Nabinger, Pablo Boggiano, Diana L. Restrepo-Osorio, Claudio Ribeiro
Application Of The Tessa Methodology In A Pilot Protocol For Participatory Evaluation Of Ecosystem Services And Agents Of Change In The Pampa Grasslands. Method Description And Lessons Learned, Daniela Schossler, Carlos Nabinger, Pablo Boggiano, Diana L. Restrepo-Osorio, Claudio Ribeiro
IGC Proceedings (1977-2023)
The Toolkit for Site-Based Assessment (Landscape) of Ecosystem Services (TESSA) is intended to be an accessible guide for low-cost methods to assess the benefits that people receive from nature at particular sites in order to generate information that can be used to influence decision-making (Pehl et al 2015). However, TESSA does not have defined protocols for grasslands ecosystems. This article focuses on the description and discussion of the lessons learned in the participatory workshops that include engaging with policy and decision-making actors. The work consisted of identifying 1) the area occupied by each coverage or use, 2) the threats and …
Analysis Of The Attitude Of Farmers Towards Innovations In The Management Of Grasslands In Poland, P. Goliński, A. Van Den Pol-Van Dasselaar, A. Paszkowski, B. Golińska
Analysis Of The Attitude Of Farmers Towards Innovations In The Management Of Grasslands In Poland, P. Goliński, A. Van Den Pol-Van Dasselaar, A. Paszkowski, B. Golińska
IGC Proceedings (1977-2023)
Innovations in the management of grasslands in Poland are important to preserve them as a source of different ecosystem services. In the farmers point of view the most promising is forage production for herbivores, particularly dairy cows. Individual farmers have different opinions about innovations. To stimulate innovations in grassland-based farming systems in Poland, it is important to determine the drivers for their promotion and to define the barriers to overcome problems by their implementation. Analysis of the attitude of Polish farmers towards innovations on grasslands were conducted within the H2020 Inno4Grass project. The majority of respondents were young and had …
Adaptive Rotational Grazing And The Story Of The Regrazed Grass Plant, L. M. Porensky, H. Wilmer, D. J. Augustine, J. D. Derner, M. Fernández-Giménez, David D. Briske, Carm Stakeholder Group
Adaptive Rotational Grazing And The Story Of The Regrazed Grass Plant, L. M. Porensky, H. Wilmer, D. J. Augustine, J. D. Derner, M. Fernández-Giménez, David D. Briske, Carm Stakeholder Group
IGC Proceedings (1977-2023)
Livestock stocking rates and decisions about how to move animals in time and space impact plant responses to livestock grazing. We report on a ranch-scale collaborative experiment comparing adaptive rotational grazing management to season-long continuous grazing during a 4.5-month grazing period during the growing season. As part of this project, stakeholders and scientists worked together to articulate their hypotheses about the mechanisms linking rotational grazing with expected vegetation outcomes. Several stakeholders expected rotational grazing to enhance the production and diversity of grazing-sensitive perennial grass species. The main hypothesized mechanism underlying this expectation was that rotation grazing should reduce regrazing of …
Ecology And Diversity Of Culturable Fungal Species Associated With Soybean Seedling Diseases In The Midwestern United States, Mirian F. Pimentel, Ali Y. Srour, Amanda J. Warner, Jason P. Bond, Carl A. Bradley, John Rupe, Martin I. Chilvers, J. Alejandro Rojas, Janette L. Jacobs, Christopher R. Little, Alison E. Robertson, Loren J. Giesler, Dean Malvick, Kiersten Wise, Albert Tenuta, Ahmad M. Fakhoury
Ecology And Diversity Of Culturable Fungal Species Associated With Soybean Seedling Diseases In The Midwestern United States, Mirian F. Pimentel, Ali Y. Srour, Amanda J. Warner, Jason P. Bond, Carl A. Bradley, John Rupe, Martin I. Chilvers, J. Alejandro Rojas, Janette L. Jacobs, Christopher R. Little, Alison E. Robertson, Loren J. Giesler, Dean Malvick, Kiersten Wise, Albert Tenuta, Ahmad M. Fakhoury
Department of Plant Pathology: Faculty Publications
Aims: To isolate and characterize fungi associated with diseased soybean seedlings in Midwestern soybean production fields and to determine the influence of environmental and edaphic factors on their incidence.
Methods and Results: Seedlings were collected from fields with seedling disease history in 2012 and 2013 for fungal isolation. Environmental and edaphic data associated with each field was collected. 3036 fungal isolates were obtained and assigned to 76 species. The most abundant genera recovered were Fusarium (73%) and Trichoderma (11.2%). Other genera included Mortierella, Clonostachys, Rhizoctonia, Alternaria, Mucor, Phoma, Macrophomina and Phomopsis. …
Recent Advances In Probiotic Application In Animal Health And Nutrition: A Review, Sarayu Bhogoju, Samuel Nahashon
Recent Advances In Probiotic Application In Animal Health And Nutrition: A Review, Sarayu Bhogoju, Samuel Nahashon
Agricultural and Environmental Sciences Faculty Research
Biotechnological advances in animal health and nutrition continue to play a significant role in the improvement of animal health, growth, and production performance. These biotechnological advancements, especially the use of direct-fed microbials, also termed probiotics, those genetically modified and otherwise, have minimized many challenges facing livestock production around the world. Such advancements result in healthy animals and animal products, such as meat, for a growing population worldwide. Increasing demand for productivity, healthy animals, and consumer food safety concerns, especially those emanating from excessive use of antibiotics or growth promoters, are a driving force for investing in safer alternatives, such as …
What Have We Learnt From Quantitative Case Reports Of Acute Lateral Ankle Sprains Injuries And Episodes Of 'Giving-Way' Of The Ankle Joint, And What Shall We Further Investigate?, Filip Gertz Lysdal, Yuehang Wang, Eamonn Delahunt, Dominic Gehring, Kyle B. Kosik, Tron Krosshaug, Yumeng Li, Kam-Ming Mok, Kati Pasanen, Alexandria Remus, Masafumi Terada, Daniel T. P. Fong
What Have We Learnt From Quantitative Case Reports Of Acute Lateral Ankle Sprains Injuries And Episodes Of 'Giving-Way' Of The Ankle Joint, And What Shall We Further Investigate?, Filip Gertz Lysdal, Yuehang Wang, Eamonn Delahunt, Dominic Gehring, Kyle B. Kosik, Tron Krosshaug, Yumeng Li, Kam-Ming Mok, Kati Pasanen, Alexandria Remus, Masafumi Terada, Daniel T. P. Fong
Athletic Training and Clinical Nutrition Faculty Publications
Lateral ankle sprains are a commonly incurred injury in sports. They have a high recurrence rate and can lead to the development of persistent injury associated symptoms. We performed a quantitative synthesis of published case reports documenting the kinematics of acute lateral ankle sprains and episodes of ‘giving-way’ of the ankle joint to provide a comprehensive description of the mechanisms. A systematic literature search was conducted to screen records within MEDLINE® and EMBASE®. Additional strategies included manual search of specific journals, as well as contacting researchers in relevant communities to retrieve unpublished data. Twenty-four cases were included in the quantitative …
The Effects Of Nuclear Factor Erythroid 2 (Nfe2)-Related Factor 2 (Nrf2) Activation In Preclinical Models Of Peripheral Neuropathic Pain, Paramita Basu, Dayna L. Averitt, Camelia Maier, Arpita Basu
The Effects Of Nuclear Factor Erythroid 2 (Nfe2)-Related Factor 2 (Nrf2) Activation In Preclinical Models Of Peripheral Neuropathic Pain, Paramita Basu, Dayna L. Averitt, Camelia Maier, Arpita Basu
Kinesiology and Nutrition Sciences Faculty Research
Oxidative stress, resulting from an imbalance between the formation of damaging free radicals and availability of protective antioxidants, can contribute to peripheral neuropathic pain conditions. Reactive oxygen and nitrogen species, as well as products of the mitochondrial metabolism such as superoxide anions, hydrogen peroxide, and hydroxyl radicals, are common free radicals. Nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2) is a transcription factor encoded by the NFE2L2 gene and is a member of the cap ‘n’ collar subfamily of basic region leucine zipper transcription factors. Under normal physiological conditions, Nrf2 remains bound to Kelch-like ECH-associated protein 1 in the cytoplasm …
Effects Of Three Different Modes Of Resistance Training On Appetite Hormones In Males With Obesity, Ali Ataeinosrat, Marjan Mosalman Haghighi, Hossein Abednatanzi, Mohammad Soltani, Abbass Ghanbari-Niaki, Akbar Nouri-Habashi, Sadegh Amani-Shalamzari, Ali Mossayebi, Mitra Khademosharie, Kelly E. Johnson, Trisha A. Vandusseldorp, Ayoub Saeidi, Hassane Zouhal
Effects Of Three Different Modes Of Resistance Training On Appetite Hormones In Males With Obesity, Ali Ataeinosrat, Marjan Mosalman Haghighi, Hossein Abednatanzi, Mohammad Soltani, Abbass Ghanbari-Niaki, Akbar Nouri-Habashi, Sadegh Amani-Shalamzari, Ali Mossayebi, Mitra Khademosharie, Kelly E. Johnson, Trisha A. Vandusseldorp, Ayoub Saeidi, Hassane Zouhal
Kinesiology
Purpose: This study explored the effect of three different modes of resistance training on appetite hormones [leptin, ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide tyrosine–tyrosine (PYY)], cardiometabolic and anthropometric measures in males with obesity. Methods: Forty-four males with obesity (age: 27.5 ± 9.4 yrs.; mean weight: 93.2 ± 2.2 kg, body mass index: 32.9 ± 1.2 kg/m2) were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups. All resistance training groups received 50 min of supervised …
Role Of Body Mass And Physical Activity In Autonomic Function Modulation On Post-Covid-19 Condition: An Observational Subanalysis Of Fit-Covid Study, Ana Paula Coelho Figueira Freire, Fabio Santos Lira, Ana Elisa Von Ah Morano, Telmo Pereira, Manuel-João Coelho-E-Silva, Armando Caseiro, Diego Giullano Destro Christofaro, Osmar Marchioto Júnior, Gilson Pires Dorneles, Luciele Guerra Minuzzi, Ricardo Aurino Pinho, Bruna Spolador De Alencar Silva
Role Of Body Mass And Physical Activity In Autonomic Function Modulation On Post-Covid-19 Condition: An Observational Subanalysis Of Fit-Covid Study, Ana Paula Coelho Figueira Freire, Fabio Santos Lira, Ana Elisa Von Ah Morano, Telmo Pereira, Manuel-João Coelho-E-Silva, Armando Caseiro, Diego Giullano Destro Christofaro, Osmar Marchioto Júnior, Gilson Pires Dorneles, Luciele Guerra Minuzzi, Ricardo Aurino Pinho, Bruna Spolador De Alencar Silva
All Faculty Scholarship for the College of Education and Professional Studies
The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates …
Changes In Apolipoprotein Abundance Dominate Proteome Responses To Prolonged Fasting In Elephant Seals, Jane I. Khudyakov, Rachel R. Holser, Craig A. Vierra, Serena T. Ly, Theron K. Niel, Basma M. Hasan, Daniel E. Crocker, Daniel P. Costa
Changes In Apolipoprotein Abundance Dominate Proteome Responses To Prolonged Fasting In Elephant Seals, Jane I. Khudyakov, Rachel R. Holser, Craig A. Vierra, Serena T. Ly, Theron K. Niel, Basma M. Hasan, Daniel E. Crocker, Daniel P. Costa
Pacific Faculty Work
Unlike many animals that reduce activity during fasting, northern elephant seals (NES) undergo prolonged fasting during energyintensive life-history stages such as reproduction and molting, fueling fasting energy needs by mobilizing fat stores accrued during foraging. NES display several unique metabolic features such as high fasting metabolic rates, elevated blood lipid and high-density lipoprotein (HDL) cholesterol levels, efficient protein sparing and resistance to oxidative stress during fasting. However, the cellular mechanisms that regulate these adaptations are still not fully understood. To examine how metabolic coordination is achieved during prolonged fasting, we profiled changes in blubber, skeletal muscle and plasma proteomes of …
Professional Development For Early Career Dber Scholars Through In-Person And Virtual Career Panel Workshops, Miranda M. Chen Musgrove, Elizabeth Genné-Bacon, Kelsey Gray, Ashley B. Heim, Anupriya Karippadath, Rita Margarida Magalhães, Brie Tripp, Anna J. Zelaya
Professional Development For Early Career Dber Scholars Through In-Person And Virtual Career Panel Workshops, Miranda M. Chen Musgrove, Elizabeth Genné-Bacon, Kelsey Gray, Ashley B. Heim, Anupriya Karippadath, Rita Margarida Magalhães, Brie Tripp, Anna J. Zelaya
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
In discipline-based education research (DBER), early career scholars, such as graduate students and postdoctoral researchers, observe a slew of possible career pathways. Yet, there is a lack of opportunities to learn about such pathways, particularly when transitioning from traditional science, technology, engineering, or math (STEM) disciplinary training into a DBER position. Thus, the DBER Scholars-in-Training Professional Development subcommittee was created within the Society for the Advancement of Biology Education Research (SABER) community to develop a collection of workshops that would serve the greatest professional development needs of early career scholars entering DBER. Through a series of surveys disseminated over multiple …
Activation Of Ras/Mapk Pathway Confers Mcl-1 Mediated Acquired Resistance To Bcl-2 Inhibitor Venetoclax In Acute Myeloid Leukemia, Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Saravanan Ganesan, Sergej N Konoplev, Shannon R Sweeney, Jeremy A Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L Battula, Yingchang Mi, Jing Wang, Courtney D Dinardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Activation Of Ras/Mapk Pathway Confers Mcl-1 Mediated Acquired Resistance To Bcl-2 Inhibitor Venetoclax In Acute Myeloid Leukemia, Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Saravanan Ganesan, Sergej N Konoplev, Shannon R Sweeney, Jeremy A Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L Battula, Yingchang Mi, Jing Wang, Courtney D Dinardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Faculty, Staff and Student Publications
Despite high initial response rates, acute myeloid leukemia (AML) treated with the BCL-2-selective inhibitor venetoclax (VEN) alone or in combinations commonly acquires resistance. We performed gene/protein expression, metabolomic and methylation analyses of isogenic AML cell lines sensitive or resistant to VEN, and identified the activation of RAS/MAPK pathway, leading to increased stability and higher levels of MCL-1 protein, as a major acquired mechanism of VEN resistance. MCL-1 sustained survival and maintained mitochondrial respiration in VEN-RE cells, which had impaired electron transport chain (ETC) complex II activity, and MCL-1 silencing or pharmacologic inhibition restored VEN sensitivity. In support of the importance …
Establishment Of Common House Geckos, Hemidactylus Frenatus Duméril & Bibron, On Saint Lucia, Aaron H. Griffing, David H. Griffing, Stephen Lesmond, Tony Gamble
Establishment Of Common House Geckos, Hemidactylus Frenatus Duméril & Bibron, On Saint Lucia, Aaron H. Griffing, David H. Griffing, Stephen Lesmond, Tony Gamble
Biological Sciences Faculty Research and Publications
No abstract provided.
A Scalable And Participatory Sustainable Rangeland Management Toolkit With A Holistic And Multidisciplinary Approach To Rehabilitate Degraded Rangelands, Mounir Louhaichi, Mouldi Gamoun, Sawsan Hassan
A Scalable And Participatory Sustainable Rangeland Management Toolkit With A Holistic And Multidisciplinary Approach To Rehabilitate Degraded Rangelands, Mounir Louhaichi, Mouldi Gamoun, Sawsan Hassan
IGC Proceedings (1977-2023)
Rangelands contribute significantly toward improving livelihoods, offering food security, trade and tourism for pastoral communities. Numerous challenges include poor government policies, loss of indigenous knowledge and top-down approaches toward sustainable rangeland rehabilitation that often fail to consider local development adoption and sustainability. In such situations, effective management is needed for sustainable rangeland ecosystem goods and services in a context characterized by rainfall unreliability, poor soil nutrient status and high uncontrolled grazing. This paper presents a new comprehensive toolkit for identifying and combining suitable and site-specific interventions aimed at reversing the trend of degraded arid rangelands. This toolbox is founded on …
Pastoralist Use Of Reseeded Fields For Additional Resilience To Climate Variability Through Alternate Livelihood Activities, D. W. Githu, J. S. Fehmi, M. Mcclaran, M. Elizabeth, A. Josephson
Pastoralist Use Of Reseeded Fields For Additional Resilience To Climate Variability Through Alternate Livelihood Activities, D. W. Githu, J. S. Fehmi, M. Mcclaran, M. Elizabeth, A. Josephson
IGC Proceedings (1977-2023)
Land degradation, climate variability, socio-economic changes and population increase are some of the factors that shrink grazing lands making forage availability less predictable and affecting the resilience of pastoralists communities. Reseeding as an intervention can rehabilitate degraded lands for profitable use through offering pastoralists alternative sources of livelihood and encourage livelihood diversification. This study evaluated two pastoral communities, the Tugen and the Njemps from Baringo County, Kenya, who have owned, managed and used reseeded fields to study the dynamics of reseeding land. A total of 193 pastoralist households were interviewed. These two pastoral communities used their fields for: dry season …
Utilizing Perennial Grass Species’ Population Patterns To Detect Looming Desertification Tipping Points In Semi-Arid Regions, F. Munyebvu-Chambara, W. C. Nesongano, M. C. Bilton, A. Linstädter
Utilizing Perennial Grass Species’ Population Patterns To Detect Looming Desertification Tipping Points In Semi-Arid Regions, F. Munyebvu-Chambara, W. C. Nesongano, M. C. Bilton, A. Linstädter
IGC Proceedings (1977-2023)
Namibia is one of the global dryland regions facing desertification threats due to overgrazing and recurrent drought. This has disastrous effects on forage provision and consequently on local livelihoods. Unfortunately, the mechanisms underlying sudden shifts of rangeland ecosystems towards a desertified state are still poorly understood. The ability to predict desertification tipping points with the aid of suitable ecological indicators is critical to ensure sustainable management of rangeland resources, which are a backbone of rural livelihood in drylands worldwide. Accordingly, we aimed to identify key perennial grass species that can be used as early-warning indicators for desertification tipping points; and …
Spatial And Temporal Variation Of Selected Water Quality Parameters In The Tanzanian Side Of Lake Victoria, Richard Joseph Kimwaga
Spatial And Temporal Variation Of Selected Water Quality Parameters In The Tanzanian Side Of Lake Victoria, Richard Joseph Kimwaga
Tanzania Journal of Engineering and Technology (TJET)
Lake Victoria’s water quality is increasingly becoming under heavy pressure mainly due to land based activities and aerial inputs which are taking place within the basin. This study was carried out to assess the spatial, including vertical and temporal, variation of the water quality of Lake Victoria on the Tanzanian side. Historical water quality data for the period from 2000 to 2016 was collected. Temperature, pH, Dissolved Oxygen (DO) and Turbidity were selected for study since they are the mostly measured and monitored water quality parameters. Land use-land cover changes were analysed using ArcGIS. ILWIS 3.7 software was used to …
Scientific And Technological Reasons, Contents And Corresponding Policies Of Constructing “Coastal Grass Belt”, Weihua Xu, Jianlin Wang, Xiaojing Liu, Qi Xie, Weicai Yang, Xiaofeng Cao, Zhensheng Li
Scientific And Technological Reasons, Contents And Corresponding Policies Of Constructing “Coastal Grass Belt”, Weihua Xu, Jianlin Wang, Xiaojing Liu, Qi Xie, Weicai Yang, Xiaofeng Cao, Zhensheng Li
Bulletin of Chinese Academy of Sciences (Chinese Version)
Not only the grain rations must be secured absolutely in China, but also the feed grains. However, the limited arable land resource in China determines that grass planting shall not "compete for land with staple food". Planting high quality salt-tolerant forage grass on the saline wasteland and developing animal husbandry production can not only meet the demand of increasing proportion of animal protein in Chinese diet structure, but more importantly, it can help to solve the problems of insufficient forage planting and import over-dependence. Hence it plays an important role in guaranteeing national food security. Therefore, it is necessary to …
Overview Of Cutting-Edge Innovation In Life Sciences: Learning From Perspective Of Broad Institute, Runzhou Zhao, Shu Liu
Overview Of Cutting-Edge Innovation In Life Sciences: Learning From Perspective Of Broad Institute, Runzhou Zhao, Shu Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Since its establishment in 2004, the Broad Institute in the United States has been dedicated to combination research innovation with management innovation. In less than 10 years, it has been enlisted as one of the world-class life sciences research institutions and become the leader and signpost of cutting-edge innovation in life sciences. Its unique development model is worthy of reference. This study showed that the high-quality innovation and development of the Broad Institute is inseparable from:(1) its focus on the diagnosis and treatment needs of major diseases for scientific research; (2) the opening up of the channel from basic research …