Life Sciences Commons^™

Whitetop (Hoary Cress) Control In Residential Situations, Taun Beddes, Michael Caron, Jacob Hadfield, Corey Ransom

All Current Publications

Whitetop (Lepidium draba, formerly Cardaria draba) is a persistent, perennial weed that grows in open, sunny areas. It spreads by seeds and rhizomes, enabling it to spread by several feet in a single season. It is common in wildlands, agricultural, and residential areas. It rapidly spreads into unhealthy lawns, landscape beds, and vegetable gardens. This fact sheet provides information on identification, lifecycle, landscape damage, and suppression and control options.

Complement Propagates Visual System Pathology After Traumatic Brain Injury, Davis Marchant Borucki

MUSC Theses and Dissertations

Background: Traumatic brain injury is associated with the development of visual system disorders, including deficits in visual acuity. Visual deficits can present with delay and worsen over time, suggesting that ongoing neuroinflammatory changes contribute to their development and progression. Complement activation is strongly associated with the neuroinflammatory response after TBI and has been shown to contribute to neuronal and synaptic loss. However, the contributions of complement activation after TBI to vision loss remains unclear.

Methods: We employed an open skull controlled cortical impact model of traumatic brain injury in adult male mice to study how TBI affects vision. Animals were …

Concepts In Animal Parasitology, Scott L. Gardner, Sue Ann Gardner

Zea E-Books Collection

Note that this version of the textbook has been superceded by the one updated in 2026, available at the UNL Pressbooks site.

The hard copy version that is for sale at lulu.com is the old version.

"This is a textbook covering concepts in animal parasitology. It is meant to be used by students, teachers, professors, researchers, and members of the public who are interested in learning about animal parasite biology, systematics, taxonomy, zoogeography, and ecology. The primary intended audience is upper-level undergraduate or graduate university students who have knowledge of basic biology and, particularly, basic animal biology. (863 pages, …

Lower Limb Muscle Activation In Young Adults Walking In Water And On Land, Christopher Long, Christopher J. Dakin, Sara A. Harper, Joonsun Park, Aaron Folau, Mark Crandall, Nathan Christensen, Talin Louder

Kinesiology and Health Science Faculty Publications

Previous research has shown that exercise interventions requiring increased activation of the tibialis anterior (TA), the primary ankle dorsiflexor, can improve walking performance in individuals with foot drop. Correspondingly, heightened drag forces experienced during walking performed in water may augment TA activation during the swing phase of gait, potentially leading to improved walking gait on land. Therefore, this study aimed to compare surface electromyographic (sEMG) activation in the TA and medial gastrocnemius (GM) during gait performed in water versus on land. Thirty-eight healthy, recreationally active young adults, comprising 18 females and 20 males, participated in the study. Each participant completed …

Macrophage-Driven Car T Cell Resistance In B Cell Lymphoma, Sae Bom Lee

USF Tampa Graduate Theses and Dissertations

Chimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment of patients with relapsed/ refractory large B cell lymphoma (LBCL). Despite its promising efficacy, a subset of patients experiences primary resistance or relapse. In Chapter 2, we explore the tumor microenvironment (TME)-induced resistance mechanisms in patients with LBCL. Analysis of the intratumoral immune infiltrates in pre-infusion tumor biopsies revealed that the levels of immunoregulatory macrophages were elevated in patients who responded poorly to axicabtagene ciloleucel (axi-cel). Using preclinical mouse B cell tumor models, we found that the CAR T-cell-produced interferon-gamma (IFN-γ) enhanced the expression of inducible nitric oxide synthase (iNOS, …

Author Correction: Long Noncoding Rna Malat1 Protects Against Osteoporosis And Bone Metastasis, Yang Zhao, Jingyuan Ning, Hongqi Teng, Yalan Deng, Marisela Sheldon, Consuelo Martinez, Annie Tian, Yutong Sun, Shinichi Nakagawa, Fan Yao, Hai Wang, Li Ma

Faculty, Staff and Student Publications

This corrects the article "Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis", 2384.

Table Of Contents, Lauren R. Yanase

Anthós

This document includes the front matter and table of contents for this issue of Anthós.

Using Dna Barcoding To Identify High-Priority Taxa (Hymenoptera: Ichneumonidae) From Great Smoky Mountains National Park, Emerie Landers, Brandon Claridge, Will Kuhn, Victoria Seymour, Hettie Peek, Scout Fluet, Jake Ramgren, Jake Phelps, Brayden Paulk, Lydia Cordner, Jeremy Blaschke

Biology Student Research

The All Taxa Biodiversity Inventory (ATBI) in Great Smoky Mountains National Park (GSMNP) seeks to document every species of living thing in the park. The ATBI is decades in progress, yet some taxa remain virtually untouched by taxonomists. Such "high priority" taxa include the hyper-diverse parasitoid wasp family Ichneumonidae. Despite the positive and multifaceted effects ichneumonids have on their environment, only a small percentage of those collected in the park have been identified as species, mostly to their complex morphology and overwhelming diversity. Recently, DNA barcoding has transformed biodiversity inventories, streamlining the process to be more rapid and efficient. To …

Native American And First-Nations Canadian And Physical Pfas Accumulations: A Literature Review, Laurel Liebeseller

University Honors Theses

Native communities' exposure to anthropogenic Per- and Polyfluoroalkyl Substances (PFAS: "Forever Chemicals") are not demographically or geographically evenly distributed. Those who live near or on contaminated land or water are the most likely to accumulate dangerous amounts of PFAS that may have serious health consequences (Tribal PFAS Working Group 2021). Areas that tend to be most contaminated include landfills, airports, and military bases. Often Black, Indigenous People of Color (BIPOC) and low-income communities are placed near these "sacrificial zones" due to historic and current policies that segregate and marginalize people and families to polluted lands creating great environmental injustices (Dixie). …

A Comprehensive Examination Of Age-Related Lower Limb Muscle Function Asymmetries Across A Variety Of Muscle Action Types, Kylee L. Heap-Eldridge, Brennan J. Thompson, Cody Fisher, Talin J. Louder, Jon Carey

Kinesiology and Health Science Faculty Publications

Previous research has found that lower limb muscle asymmetries increase with age and are linked to fall and injury risks. However, past studies lack a wide variety of muscle function modes and measures as well as comparison to a comparable younger age group. The purpose of this study was to examine age-related lower limb muscle function asymmetries across a variety of muscle action types and velocities in young and old adults. Lower limb balance, strength, power, and velocity were evaluated with concentric, isometric, isotonic, and eccentric muscle actions during a single-leg stance test and on single- and multi-joint dynamometers in …

Fleq And Gac/Rsm-Mediated Regulation Of Biofilm Formation And Swarming Motility In Pseudomonas Fluorescens, Alexander Benito Pastora

Dartmouth College Ph.D Dissertations

Pseudomonas fluorescens is a gram-negative Gammaproteobacterium that survives and persists in diverse environments. This survivability is dependent on the bacterium’s ability to form a biofilm. Within Pseudomonas fluorescens, biofilm formation is a complex and dynamic process involving multiple protein- and polysaccharide-based components which each individually serve a specific purpose. Of these components, the repeats-in-toxin (RTX) adhesins LapA and MapA are critical for biofilm formation. Specifically, LapA is important for initial establishment of a biofilm and MapA is important in forming a fully mature biofilm. Deployment of the RTX adhesins during biofilm formation is a highly coordinated process involving multiple …

Protein Nanoparticles As Vaccine Platforms For Human And Zoonotic Viruses, Kush Kumar Pandey, Bikash R. Sahoo, Asit K. Pattnaik

Nebraska Center for Virology: Faculty Publications

Vaccines are one of the most effective medical interventions, playing a pivotal role in treating infectious diseases. Although traditional vaccines comprise killed, inactivated, or liveattenuated pathogens that have resulted in protective immune responses, the negative consequences of their administration have been well appreciated. Modern vaccines have evolved to contain purified antigenic subunits, epitopes, or antigen-encoding mRNAs, rendering them relatively safe. However, reduced humoral and cellular responses pose major challenges to these subunit vaccines. Protein nanoparticle (PNP)-based vaccines have garnered substantial interest in recent years for their ability to present a repetitive array of antigens for improving immunogenicity and enhancing protective …

Determining The Optimal Dosage Of Dexmedetomidine For Smooth Emergence In Older Patients Undergoing Spinal Surgery: A Study Of 44 Cases, Hyoeun Ahn, Yun Jeong Chae, Gyu Bin Choi, Min Gyu Lee, Ji Young Yoo

Faculty, Staff and Student Publications

BACKGROUND Emergence agitation, or delirium, occurs during early recovery from general anesthesia and involves disorientation, excitation, and uncontrolled physical movements. Dexmedetomidine is an alpha agonist that has sedative, anxiolytic, analgesic, and sympatholytic activities and is used as a continuous infusion to prevent emergence agitation. This study aimed to evaluate patients aged 65 years and older undergoing general anesthesia to determine the 90% effective dose (ED90) of dexmedetomidine continuous intraoperative infusion to prevent emergence agitation. MATERIAL AND METHODS We enrolled 44 patients aged 65 years and older undergoing spinal surgery under general anesthesia. Dexmedetomidine administration commenced 30 minutes before surgery completion, …

Slime Molds (Myxomycetes) Causing A “Disease” In Crop Plants And Cultivated Mushrooms, Zhaojuan Zhang, Chao Zhi, Yu Li, Steven L. Stephenson, Pu Liu

Biological Sciences Faculty Publications and Presentations

Myxomycetes (plasmodial slime molds) are eukaryotic protist predators that are associated with wood, leaf litter, and soil in forests, where they feed on bacteria, protozoans, and (to a more limited extent) fungi. The health of crop plants is essential because they represent a primary food source for humans. However, when myxomycetes produce numerous fruiting bodies on the stems and leaves of crop plants, which is herein referred to as a myxomycete colonization, this has the potential of interfering with plant photosynthesis, transpiration and respiration by blocking out light and covering stomata. Myxomycetes are not pathogens, but their occurrence on plants …

Unveiling Parkinson’S: Empowering Our Community Through Awareness, Lindsay Spindler, Lorraine Wilson, Jill Jumper, Donna Walls, Annie Bane, Priscilla Wyatt, Julie St-John

CSKLS Annual Conference

Awareness about situations or conditions has brought many changes to public policy, treatment methods, and community engagement, to name just a few. Awareness also creates a culture of “seeing” people who may feel unseen or dismissed. One particular group that may feel this way are people with Parkinson’s disease. Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily resulting from a decrease in dopamine levels. This decrease in dopamine can lead to deficiencies in motor control and cognitive function that can include slow and uncoordinated movement, loss of balance, loss of smell, and decreased cognitive function¹. The implementation …

The Relationship Between Hand Grip Strength, Pinch Strength, Forearm Strength, And Range Of Motion In Various Anatomical Positions, Cali Carter, Lindsay Spindler, Chuck Ruot

CSKLS Annual Conference

INTRODUCTION: The ability of the hands to grasp and manipulate is fundamental in the performance of activities of daily living (ADL)¹. ADL refers to those elementary tasks that allow a person to function with autonomy and independence. For ADL’s to be accomplished innervation, strength, and range of motion (ROM) are necessary to complete tasks such as opening a water bottle, gripping a coffee mug, inserting a key into a door lock, or simply getting dressed.

PURPOSE: The purpose of this study was to measure the relationship between hand strength, pinch strength, forearm strength and ROM in …

Designing Of Human Serum Albumin Nanoparticles For Drug Delivery: A Potential Use Of Anticancer Treatment, Ali Al-Ani, Rasha Alsahlanee

Karbala International Journal of Modern Science

Human serum albumin (HSA) nanoparticles have been widely used as versatile drug delivery systems for improving the efficiency and pharmaceutical properties of drugs. The present study aimed to design HSA nanoparticle encapsulated with the hydrophobic anticancer pyridine derivative (2-((2-([1,1'-biphenyl]-4-yl)imidazo[1,2-a]pyrimidin-3-yl)methylene)hydrazine-1-carbothioamide (BIPHC)). The synthesis of HSA-BIPHC nanoparticles was achieved using a desolvation process. Atomic force microscopy (AFM) analysis showed the average size of HSA-BIPHC nanoparticles was 80.21 nm. The percentages of entrapment efficacy, loading capacity and production yield were 98.11%, 9.77% and 91.29%, respectively. An In vitro release study revealed that HSA-BIPHC nanoparticles displayed fast dissolution at pH 7.4 compared to pH …

Modified Toulmin's Argumentation Model Based On Prior Experiences, Ali Hadi Hasan, Mohamad Ab. Saleh, Ahmed T. Sadiq

Karbala International Journal of Modern Science

Our work focuses on the usefulness of previously stored correct extracted results, which form a sort of stored knowledge got from previous experiences, from enhancing Toulmin's argument model that deals with drug conflict problems in therapeutic diagnostics. New patients are entered using friendly user interface to store in files and then they are matched with the records of previous results, patients’ symptoms and histories datasets which also contain the correct best drugs extracted results. If the new entered record of a patient is matching with any previous record then the correct result of drug will be found immediately and displayed. …

Models And Sufficiency Interpretation For Estimating Critical Soil Test Values For The Fertilizer Recommendation Support Tool, N. A. Slaton, A. Pearce, L. Gatiboni, D. Osmond, C. Bolster, F. Miquez, J. Clark, J. Dhillon, B. Farmaha, D. Kaiser, S. Lyons, A. Margenot, A. Moore, D. Ruiz Diaz, D. Sotomayor, J. Spackman, J. Spargo, M. Yost

Plants, Soils, and Climate Faculty Publications

Soil test correlation determines whether a soil test can be used to predict the need for fertilization based on the critical soil test value (CSTV). Our objectives were to compare the CSTV estimated from five combinations of correlation models and yield sufficiency interpretations and to select one method for soil test correlation performed with the Fertilizer Recommendation Support Tool (FRST). Four models were fit to three datasets with strong (Mehlich-1 K), moderate (Mehlich-3 K), or weak (Olsen P) correlations between soil test P or K and crop relative yield. We tested the arcsine-log calibration curve (ALCC), exponential (EXP), linear plateau …

Salmon Mislabeling Rates Uncovered In Restaurants And Grocery Stores In Seattle, Jewel L. Garcia, Jewel L. Garcia

Honors Projects

Salmon has been a cultural icon in Seattle, Washington for many generations because it has and continues to sustain the people who reside on this land. Seafood fraud, in which a seafood’s genetic identity does not match its vendor-claimed identity, is not a new phenomenon, and many studies have been conducted internationally to explore the extent of this issue. With human and environmental health concerns on the line, a salmon fraud (mislabeling) study must be conducted in a state where immensely high salmon sales and serious recreational efforts occur to assess Seattle’s marketplace honesty. By genetically barcoding the highly conserved …

Establishment Of Bacteroides In The Gut And Its Role In The Cystic Fibrosis Gut-Lung Axis, Rebecca A. Valls

Dartmouth College Ph.D Dissertations

In the quest to understand the complex interplay between the gut microbiota and cystic fibrosis (CF), a disease characterized by chronic upper respiratory complications and an exacerbated proinflammatory response, our lab engaged in a collaborative study with Dartmouth-Hitchcock Medical Center (DHMC) to characterize the gut microbiota of pediatric CF patients. Initial analyses established a connection between gut microbial composition and respiratory health, particularly highlighting a scarcity of Bacteroides species compared to healthy controls. In following investigations, we utilized random forest models to understand how stool microbiota may influence clinical outcomes of these pediatric CF patients, including: age, upper respiratory infections, …

Application Of Simultaneous Uncertainty Quantification And Segmentation For Oropharyngeal Cancer Use-Case With Bayesian Deep Learning, Jaakko Sahlsten, Joel Jaskari, Kareem A Wahid, Sara Ahmed, Enrico Glerean, Benjamin H Kann, Clifton D Fuller, Mohamed A Naser, Kimmo Kaski

Faculty, Staff and Student Publications

BACKGROUND: Radiotherapy is a core treatment modality for oropharyngeal cancer (OPC), where the primary gross tumor volume (GTVp) is manually segmented with high interobserver variability. This calls for reliable and trustworthy automated tools in clinician workflow. Therefore, accurate uncertainty quantification and its downstream utilization is critical.

METHODS: Here we propose uncertainty-aware deep learning for OPC GTVp segmentation, and illustrate the utility of uncertainty in multiple applications. We examine two Bayesian deep learning (BDL) models and eight uncertainty measures, and utilize a large multi-institute dataset of 292 PET/CT scans to systematically analyze our approach.

RESULTS: We show that our uncertainty-based approach …

Quantifying Variation Across 16s Rrna Gene Sequencing Runs In Human Microbiome Studies, Andrew J. Hoisington, Christopher E. Stamper, Joseph C. Ellis, Christopher A. Lowry, Lisa A. Brenner

Faculty Publications

Recent microbiome research has incorporated a higher number of samples through more participants in a study, longitudinal studies, and metanalysis between studies. Physical limitations in a sequencing machine can result in samples spread across sequencing runs. Here we present the results of sequencing nearly 1000 16S rRNA gene sequences in fecal (stabilized and swab) and oral (swab) samples from multiple human microbiome studies and positive controls that were conducted with identical standard operating procedures. Sequencing was performed in the same center across 18 different runs. The simplified mock community showed limitations in accuracy, while precision (e.g., technical variation) was robust …

Knock And The Door Shall Be Opened Unto You, Using Strength And Conditioning As A Tool To Open Doors For Ministry, Tim Dornemann

CSKLS Annual Conference

This professional presentation will discuss how the power of meeting a need can open doors for ministry. Christian Sports Performance Ministry utilizes strength and conditioning to encourage, equip, and enable athletes, coaches, and educators to create relationships through which the Gospel can be shared. In areas of the world where current conditioning methods are not commonplace, education on how to enhance physical performance can be very attractive.

In conjunction with Athletes in Action Philippines, Christian Sports Performance has successfully been using strength and conditioning to open doors for ministry since 2011. Initially, a skill-based training system was developed and used …

Germination And Seedling Growth Of Native Uae Plant Species: The Combined Effects Of Elevated Co2 And Temperature, Nour Elhouda Debouza

Thesis/ Dissertation Defenses

The dissertation offers an extensive analysis of the physiological adaptations and coping strategies of native plant species in the United Arab Emirates (UAE) to the elevated levels of atmospheric carbon dioxide (CO2) and temperature, within the broader context of human-induced climate change. Given the arid climate of the UAE, understanding how native species respond to environmental stressors is critical for the preservation of biodiversity and the development of sustainable agricultural practices. This study focuses specifically on the germination and early growth stages of three crucial native species—Senna italica, Prosopis cineraria, and Tephrosia nubica—under controlled conditions that simulate future climatic scenarios. …

An Epigenetically Driven Relationship Between Parental Ptsd And Inflammatory Disease In Offspring: A Proposal, Emma Griffith, Kevin P. Kaut

Journal of Neuropsychology and Behavioral Processes

Could a combat veteran's horrific experiences in early-2000s Afghanistan have a direct, biological impact on his or her now-adult daughter's risk of a heart attack later in her life? This concept would have been unapologetically mocked a mere twenty years ago, and it has only been in the past decade that the new field of epigenetics has revealed a distinct possibility for this event to actually take place—for parents' experiences to profoundly influence the biology of their children. The major objective of this research project is to argue for the legitimacy of this theoretical phenomenon by discussing the latest data …

Phototaxis In The Terrestrial Isopod: A Mechanism For Investigating Invertebrate Learning And Memory, Christopher Buzzelli, Jessica Kent, Chelsea Pawlak, Kevin P. Kaut

Journal of Neuropsychology and Behavioral Processes

Isopods readily explore new environments and typically prefer contexts with lower levels of illumination (i.e., negative phototaxis). In the first of two behavioral experiments reported here, the ability of isopods to discriminate between light and dark nesting regions was confirmed, although evidence suggests an initial ‘instinctive’ draw toward a darker context. Extending these findings to experiment 2, isopods were trained against their negatively phototaxic tendency and had to exit a darkened start chamber in order to locate nesting material in a brighter chamber. Within-session improvements in latency to enter the nesting region were noted across training trials, coupled with evidence …

Stability And Mobility: A Lesson From The Body, For The Body, Marc Apkarian

CSKLS Annual Conference

ABSTRACT

Whether for activities of daily living, occupation, or sport and exercise, coordinated, orchestrated movement of the body is necessary for meaningful function and motion. The musculoskeletal system is responsible for facilitating functional movement, while ensuring stability and mobility in associated regions of the body. Stability concerns itself with the ability to maintain control of joint movement or positioning, whereas mobility has to do with the ability to facilitate coordinated, unrestricted movement.

In functional movement training, a popular refrain often heard is “proximal stability aids distal mobility”. This suggests that good musculoskeletal stability in the core of the body (near …

Mukha Bhastrika On Reaction Time In Male High School Athletes: A Pilot Study, Malachi D. Ruiz, Matthew D. Ruiz

CSKLS Annual Conference

This pilot study investigates the potential impact of yoga (Mukha Bhastrika) practice on reaction time in male high school athletes. While existing literature emphasizes the importance of reaction time in contact sports and the potential of calming exercises like yoga to reduce it, there remains a gap in the literature focusing on male high school athletes in contact sports. This pilot study utilized a randomized controlled trial with ten male high school athletes. The participants were divided into two groups: one practicing Mukha Bhastrika and the other serving as a control group which simply rested between reaction time tests. Reaction …

Distinct Expression Patterns Of Hedgehog Signaling Components In Mouse Gustatory System During Postnatal Tongue Development And Adult Homeostasis, Archana Kumari, Nicole E Franks, Libo Li, Gabrielle Audu, Sarah Liskowicz, John D Johnson, Charlotte M Mistretta, Benjamin L Allen

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The Hedgehog (HH) pathway regulates embryonic development of anterior tongue taste fungiform papilla (FP) and the posterior circumvallate (CVP) and foliate (FOP) taste papillae. HH signaling also mediates taste organ maintenance and regeneration in adults. However, there are knowledge gaps in HH pathway component expression during postnatal taste organ differentiation and maturation. Importantly, the HH transcriptional effectors GLI1, GLI2 and GLI3 have not been investigated in early postnatal stages; the HH receptors PTCH1, GAS1, CDON and HHIP, required to either drive HH pathway activation or antagonism, also remain unexplored. Using lacZ reporter mouse models, we mapped expression of the HH …