Life Sciences Commons^™

In Vivo Expression Profiling Of Listeria Monocytogenes Internalins (Inlf, Inlp, Inlj) And Their Corresponding Host Receptors (Vim, Afdn, Muc2) Using A Rabbit Ligated Intestinal Loop Model, Nawar Al-Janabi, Nadhim Mushtaq Hashim Al-Bderee, Zahraa M. Madania, Mohanad Jawad Kadhim

Karbala International Journal of Modern Science

Listeria monocytogenes is a Gram-positive pathogen that causes severe infections, particularly in immunocompromised individuals. Internalin genes are important virulence factors that facilitate the bacterium's invasion of host cells. This research aimed to quantify in vivo expression of selected internalin genes (inlF, inlP, and inlJ) and their corresponding host receptors (VIM, AFDN, and MUC2) during L. monocytogenes infection. To achieve this aim, a rabbit ligated intestinal loop model was constructed comprising two intestinal loops. The first loop was injected with 1 mL of L. monocytogenes (1 × 10⁷ CFU/mL), while the second loop was injected with 1 mL of PBS as …

Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta

Karbala International Journal of Modern Science

It has previously been shown that exogenous bacterial ribosomes added to somatic cells and various cancer cell lines generate ribosome-induced cell clusters (RICs) capable of transdifferentiating into multiple cellular lineages. However, the scope of ribosome-induced transdifferentiation in cancer cells remains poorly understood. This study aimed to analyze the effects of exogenous ribosome incorporation on human cancer cell lines, specifically the intestinal epithelial cell line Caco-2 and the hepatocellular carcinoma cell line HepG2. Caco-2 and HepG2 cells were cultured with purified bacterial ribosomes in human ES/iPS cell medium after trypsinization, resulting in the formation of ribosome-induced Caco-2 (RICs-Ca) and HepG2 (RICs-He) …

Selenoprotein P And Selenium As Potential Diagnostic Biomarkers For Breast Cancer Patients, Farah A. Rashid, Rawaa A. Ali, Hanaa A. Ali

Karbala International Journal of Modern Science

Breast cancer incidence increases in last decade. Oxidative stress increases during cancer development causes consuming of antioxidants. Selenium and its transporting protein, selenoprotein P have an important role in redox homeostasis. This study aims to investigate whether or not selenium and selenoprotein P could be diagnostic biomarkers for breast cancer patients. This study was included 30 individuals in control group who is age- and BMI-matched with 60 breast cancer patients. Selenium was measured by colorimetric assay kit and selenoprotein P was determined by Sandwich ELISA kits. The results indicate significant decrease (p < 0.0001) of serum selenium and selenoprotein P in breast cancer patients compared to control. A positive significant correlation (r = 0.6214, p < 0.0001) was found between selenium and selenoprotein P in breast cancer patients. Selenium has an excellent diagnostic accuracy with area under curve 0.9831, sensitivity 95% and specificity 100% at cut-off less than 3.54 mmol/L. Furthermore, selenoprotein P has also an excellent area under curve 0.9958 with sensitivity 96.77% and specificity 100% at cut-off less than 4.15 ng/ml. These exploratory findings appear that selenium and selenoprotein P could be potential diagnostic biomarkers for breast cancer patients. Further investigations in large-multicenter populations are needed to confirm results.

Tapping Into The Ocean’S Hidden Energy: Feasibility Of A 5 Mw Otec Installation In North Bali, Widodo Setiyo Pranowo, Yani Permanawati, Gisela Malya Asoka Anindita, Agung Kurniawan, Albertus Sulaiman, Johar Setiyadi, Safri Burhanuddin, Ivonne Milichristi Radjawane, Hansan Park, Endro Sigit Kurniawan

Karbala International Journal of Modern Science

Indonesia is an archipelagic country surrounded by water and faces energy challenges due to the low use of renewable energy. Among the potential renewable options, marine energy is a particularly suitable resource given the country’s geographical nature. Based on this discussion, seawater temperature can be used as an alternative ocean thermal en-ergy known as ocean thermal energy conversion (OTEC) by using the difference in sea surface and deep-sea water temperatures. Therefore, this study aimed to examine OTEC installations in North Bali waters using closed-cycle OTEC calculations for a 5 MW system. Following this objective, we examined the water conditions by …

Development Of Novel Plasminogen Activators From Fragments Of Streptokinase Enzyme, Vijay G Mr

Theses and Dissertations

Thrombotic disorders such as myocardial infarction, ischemic stroke, pulmonary embolism and deep vein thrombosis remain major causes of mortality and disability worldwide, creating a continuing need for effective, safe and affordable thrombolytic therapy. Streptokinase is one of the most widely used plasminogen activators because of its activity, low cost and broad availability. However, its wider clinical utility is limited by high immunogenicity, allergic reactions, neutralizing antibody formation and poor suitability for repeat administration. This thesis aimed to develop novel streptokinase-derived plasminogen activators by identifying smaller functional fragments that retain thrombolytic activity while potentially reducing immunogenicity.

A literature-guided fragment-based strategy was …

Lameness In Dairy Cattle: A Practical Overview, Drew Swartz, Kalen Taylor, Jacob Hadfield, Justin Wyatt Clawson

All Current Publications

This fact sheet provides an overview of lameness in dairy cattle, including what it is, why it matters, and how to recognize and manage it. Information is geared toward producers, consultants, and educators.

Oregon State Rank Assessment For California Pinefoot (Pityopus Californicus), Lindsey K. Wise

Institute for Natural Resources Publications

Oregon state conservation status assessment for California Pinefoot (Pityopus californicus) using NatureServe methodology, 2026.

The Effects Of Anti-Gdnf On The Sensory And Autonomic Nervous System In The Heart, Tryphosa Konadu

Honors Theses

Heart disease is the number one leading cause of death; about 1 in every five deaths is due to heart disease. “Heart disease” is a catch-all phrase that encompasses a variety of conditions that affect the heart’s structure and function. Many of these symptoms can be attributed to dysfunction within the parasympathetic, sympathetic, and sensory nervous systems. Neurotrophic factors like GDNF (Glial cell line-derived neurotrophic factor), BDNF (Brain-derived neurotrophic factor), and NGF (Nerve growth factor) promotes neuronal survival, and regeneration of the nerve fibers of the heart, especially sensory and autonomic nerve fibers. Studies have suggested that increased expression of …

Drifting Neurons, Stable Geometry: Population Representations Of Instrumental Behavior In The Dorsomedial Striatum, Arati Sharma

Dartmouth College Ph.D Dissertations

The brain reliably supports learned behaviors over long periods of time despite continual biological changes that alter the activity of individual neurons, and the connections between them. For learned behaviors to persist, the information stored in neural populations must remain accessible even when the activity of individual neurons changes. Understanding how the brain achieves this is a fundamental challenge in neuroscience. The dorsomedial striatum (DMS) is critical for instrumental behavior, encoding information about actions, outcomes, and their relationships. Although extensive work has characterized the role of the DMS during learning and performance, less is known about how task-related information is …

Flexible Concurrent Training In Remote Settings, Christopher Bonilla

Doctoral Dissertations and Projects

The purpose of this study was to compare the effects of a trainee-driven flexible concurrent training program to a traditional fixed concurrent training program over 16 weeks of remote training in recreationally trained individuals. Participants were randomized into a flexible group that selected workouts based on daily perceived readiness or a control group that followed a fixed training schedule. The primary outcome was a total fitness score derived from a three-repetition maximum deadlift, a two-minute push-up test, and a two-mile run, assessed every four weeks. A secondary analysis used multilevel modeling to examine whether self-reported sleep duration predicted perceived readiness …

Surveying First-Year Stem Students’ Self-Reported Knowledge, Skills, And Attitudes Towards Teamwork, Gregory R. Goldsmith, Camilla Acosta

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The ability to work in a team is cited as a key outcome for many undergraduate Science, Technology, Engineering, and Mathematics (STEM) programs, both as a method for improving learning and as a highly desired trait for employers. Despite a growing focus on teamwork, our ability to design appropriate teamwork curriculum is limited by our poor understanding of what students arriving at university know about teamwork, what teamwork skills they consider themselves to possess, and their attitudes towards teamwork. We delivered a mixed-methods survey to first-year STEM undergraduate students (n = 205) to benchmark knowledge, skills and attitudes towards …

Three Common Hoof Problems In Dairy Cows: What To Look For And How To Prevent Them, Drew Swartz, Kalen Taylor, Jacob Hadfield, Justin Wyatt Clawson

All Current Publications

This fact sheet covers the three most common hoof lesions in dairy cows and explains why they matter and how to prevent them on your farm.

Digital Dermatitis, Sole Ulcers, And White Line Disease In Dairy Cattle: Pathogens, Diagnosis, And Treatment, Drew Swartz, Kalen Taylor, Jacob Hadfield, Justin Wyatt Clawson

All Current Publications

This fact sheet focuses on three common hoof lesions in dairy cattle: digital dermatitis, sole ulcers, and white line disease, and describes how differences in pathogenesis and risk factors influence diagnosis, prevention, and treatment.

Summer Research Internships In Agricultural Biotechnology For Off-Campus Undergraduate Students, Aaron J. Thomas

Funded Research Records

No abstract provided.

Towards 2035: Future Forms And Strategic Path Of Chinese Agriculture, Liu Tao, Zeyu Yang, Zhaohui Dong

Bulletin of Chinese Academy of Sciences (Chinese Version)

Agricultural modernization is an integral component of the national modernization. Toward 2035, China’s agricultural system confronts multiple challenges, including increasing resource and environmental pressures, rapid upgrading of residents’ consumption structure, and in-depth adjustments in the international supply chain pattern. Meanwhile, it also embraces a series of opportunities brought by transformations in agricultural production technologies and models driven by artificial intelligence, biotechnology, and engineering technology. Based on the perspective of national medium and long-term development strategy, this study sorts out the internal constraints, external opportunities, and development drivers faced by China’s agriculture. It explores six major strategic trends—ecological, intelligent, customized, facility-based, …

Plant Diversity In Laos, And Its Strategic Significance For Building China-Laos Community With A Shared Future For Biodiversity, Meng Honghu, Bo Li, Wenbin Yu, Yaowu Xing

Bulletin of Chinese Academy of Sciences (Chinese Version)

Laos is the first country to sign the bilateral cooperation document for construction of the community with a shared future with China. Over the years, Laos and China have established clear directions for cooperation in politics, economy, security, culture, and ecology, opening a new chapter in the development of China-Laos relations. At present, global environmental governance is facing severe challenges, and the biodiversity loss has become a major international issue of growing concern. Nevertheless, biodiversity conservation and sustainable development remain relatively limited. Laos shares a boarder with China and is characterized by complex natural environments with rich plant resource. Yet, …

Progress And Prospective Of New Pollutants Study, Ruan Ting, Chunyang Liao, Yawei Wang, Maoyong Song, Yaqi Cai, Guibin Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The governance of new pollutants has been becoming a critical strategic demand for the high-quality development of China. The policy will be further advanced during the coming National 15th Five-Year Plan period. Nevertheless, significant challenges remain in aspects such as list of controlled chemicals, standard development, measurement methods, alternative approaches, and remediation techniques. Existing experience in addressing traditional pollutants remains insufficient to adequately address the concealed and complex ecological and/or health risks associated with new pollutants. Thus, a strengthening of basic research is the optimal approach to tackling these challenges and avoiding detours. To better identify the critical scientific challenges …

Black Soil Organic Carbon Plays A Critical Role In Ensuring Food Security, Zhang Xingyi, Qingsong Shen, Mingming Guo, Na Li, Qiang Chen, Wei Hu, Jianye Li, Yimin Chen, Yansheng Li, Xiaobin Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Carbon-rich Black Soils are an important natural resource ensuring China’s food security, and their soil carbon stocks are closely related to grain production capacity. Based on nearly two decades of regional survey data and long-term field experiments, this study systematically investigated the dynamics of soil organic matter (SOM), its response relationship with crop productivity, and strategies for soil fertility improvement. The results showed that soil carbon stocks in the topsoil (0–20 cm) of the Black Soil region in Northeast China have declined by approximately 60%. In 2019, the regional average SOM content was approximately 36 g/kg and was decreasing at …

Multi-Sensor Tracking Reveals The Extent Of Nocturnal Migration In Landbirds, Paul Dufour, Raphaël Nussbaumer, Paul Doniol-Valcroze, Yann Rime, Peter Adamík, Susanne Åkesson, Raphaël Arlettaz, Arnaud G. Barras, Nyambayar Batbayar, Andrea Contina

School of Integrative Biological & Chemical Sciences Faculty Publications

Most bird species are diurnal but drastically change their diel cycle of activity to migrate at night. Nocturnal migration has been documented using different methods (e.g., experiments, radar and radio tracking, and acoustic monitoring), but accurately quantifying the proportion of nocturnal versus diurnal flight at the individual and species levels, and understanding how this behavior evolved across the avian tree, has remained methodologically challenging.1,2,3 Such uncertainty is not only of theoretical importance but also limits our ability to mitigate conservation threats, particularly from light pollution and building collisions.4,5,6 With multi-sensor …

Catalogue Of The Water Striders (Hemiptera: Gerridae) Of Mississippi, Chase G. Fry, Patricia L.S. Wooden

Midsouth Entomologist

Water striders (Hemiptera: Gerridae) are skating aquatic insects with piercing-sucking mouthparts that opportunistically feed on prey trapped by surface tension. The presence or absence of water striders and other aquatic Hemiptera in water systems may be important indicators of water quality. Despite their importance, the last aquatic Hemiptera checklist for the state was published in 1988. Since this publication, humans have altered waterways to meet their needs, and Gerridae taxonomy has continued to evolve. This study aims to create a current checklist of Gerridae, to provide a more comprehensive understanding of the species found in Mississippi before aquatic habitats are …

2025 Soybean Invertebrate Losses In The United States, Fred R. Musser, Sebe A. Brown, Tim Bryant, Whitney D. Crow, Jeffrey A. Davis, Christina Difonzo, Ashleigh M. Faris, Chase Floyd, Scott H. Graham, Jeremy K. Greene, Kelly A. Hamby, David Kerns, Janet Knodel, David Owens, Dominic D. Reisig, Phillip M. Roberts, Nicholas J. Seiter, Adam J. Sisson, Benjamin C. Thrash, Kelley J. Tilmon, Adam J. Varenhorst

Midsouth Entomologist

Estimated management costs and losses due to insects and other invertebrates in soybeans during the 2025 growing season were collected and compiled from 20 states to provide a record of insect pressure and management practices for the year. These annual estimates provide a historical record of pest pressure and insect management and have been compiled in some states since 2004. Participating states accounted for 68% of soybean acreage in the United States, with near 100% participation in the southern states. As has been true in previous years, the stink bug complex was the costliest insect pest in soybean followed by …

New Paradigm Of Forestry And Grassland Research Driven By Artificial Intelligence, Zhang Huaiqing, Jiaojun Zhu, Yang Liu, Tingdong Yang, Tian Gao, Jing Zhang, Xueyan Zhu, Yan Chen, Xian Jiang, Zeyu Cui, Jingwei Tan, Kexin Lei

Bulletin of Chinese Academy of Sciences (Chinese Version)

Addressing the current limitations in forestry and grassland research, particularly in cross-scale system cognition, complex process mechanism representation, and multi-scenario simulation, this study proposes an artificial intelligence-driven paradigm reconstruction framework, to shift the research model from experience-oriented approaches toward data- and intelligence-driven integration. On this basis, the study systematically establishes a multidimensional mapping between artificial intelligence and forestry and grassland research across research objects, processes, and objectives, and clarifies their intrinsic coupling mechanisms and technical pathways. Furthermore, it develops a foundational capability system to support the new paradigm from four key dimensions: data, computing power, models, and applications. By examining …

Reel Into Fishing!: Providing A Recreational Fishing Education Program For Youth, Amelia Valente, Douglas R. Zemeckis, Lisa Morse, Gene Nigro

Journal of Extension

New Jersey is known as the Garden State, but with over 130 miles of Atlantic coastline, it also has very productive marine ecosystems that offer numerous opportunities for recreational marine fishing. The International Game Fish Association, a nonprofit organization committed to the conservation of game fish and the promotion of responsible, ethical angling practices, collaborated with Rutgers Cooperative Extension to host a youth educational program entitled Reel Into Fishing! The objective is to educate participants through hands-on engagement on ethical fishing practices and marine science to help develop the next generation of responsible anglers.

Look Out For Our Kind, Christof Koch

Animal Sentience

Strongly supportive overall of Birch’s broad tent Sentience Project, I offer an alternative dyadic, single-class, two-stage process based on estimating the probability for sentience, and the associated confidence, for any individual or taxonomic group. I criticize Birch’s narrow computational framework when addressing the question of algorithmic sentience; there are alternative approaches.

Ai Is Not The Kind Of Thing That Can Ever Be Sentient, Lori Marino

Animal Sentience

Sentience evolved to allow organisms to move through their environment avoiding harms and achieving benefits. Sentience did not evolve from computation. It evolved from valenced feelings. AI (even robots) are not embodied and are not the kind of thing that needs to be sentient. There is no way to get from computations to feelings. They are qualitatively different things. We should avoid being lulled into thinking that an inanimate object designed to engage our propensity for anthropomorphism, like AI, is actually a mind.

Spatial Identity In Transition: Revitalizing Surakarta’S Heritage Markets Through Community-Based Placemaking, Eko Nursanty, Sri Mulyani, I Wayan Andhika Widiantara, Arturo Galay Cauba

Journal of Environmental Science and Sustainable Development

Traditional markets are essential socio-cultural infrastructures in heritage cities, shaping everyday interactions, economic life, and collective memory. In Surakarta, four historic markets—Pasar Gede, Pasar Klewer, Pasar Legi, and Pasar Triwindu—sustain the city’s urban identity. However, rapid modernization, commercial restructuring, and shifting consumer behavior have disrupted their spatial and symbolic continuity, raising concerns about the erosion of cultural meaning. Previous studies examined traditional markets mainly from economic or architectural perspectives, rarely exploring how their multidimensional identity evolves under urban transformation. This study investigates how spatial, social, symbolic, and environmental dimensions collectively shape market-based authenticity and the urban identity of Surakarta. A …

Comparison Of Methods For Defatted Human Milk And Nutrient Composition: An Experimental Study, Kristin Cheng, Gina O'Toole, Stephanie Chang, Richard Chang, John Miklavcic

Food Science Faculty Articles and Research

Background

Human milk is considered the gold standard for infant nutrition; however, it is often discontinued in chylothorax and severe very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency. As an alternative to complete human milk restriction, defatted human milk may be fed, though it may not fully support optimal infant growth and development. This study aimed to assess the micronutrient profile of defatted human milk.

Methods

Human milk was obtained from UCSD Human Milk Research Biorepository (San Diego, CA). Thirty samples representing 10 independent expressions in the morning, afternoon, and evening were pooled for analysis. Fat removal was performed by centrifugation at …

Bull’S-Eye On Borrelia: A Commensal And Consequential Pathogen, Alan L. Gillen

Faculty Publications and Presentations

If Lyme disease causes such urgent and chronic disease issues, where do Borrelia bacteria and ticks fit into a very good creation (Genesis 1)? How did bacteria and ticks change to rely on different hosts and blood for survival? And how are these adaptations informing today’s research in bacteriology, immunology, entomology, and disease ecology? The purposeful placement of Borrelia (Fig. 1) is most likely in the gut of wild mice (Fig. 2), not domesticated mice nor man. The bacteria are communalistic in wild mice, where they may be probiotic for mutual good (Fig. 2)—the Creator made it for good at …

Mechanistic Determination Of Host Environmental Impacts On Shigella Virulence, Nicholas E. Dickenson

Funded Research Records

No abstract provided.

Transcriptomic And Genomic Insights Into Nutrient Stress Responses And Subgenome Evolution In Chenopodium, Ashley Kathleen Marcheschi

Theses and Dissertations

Chenopodium is a diverse genus of nutritionally and ecologically important species in the Amaranthaceae family. This thesis investigates two outstanding questions in the genus: how Chenopodium quinoa responds transcriptionally to nutrient deficiency and how Australian Chenopodium species are related through their subgenomic ancestry and evolutionary history. First, we characterized transcriptomic responses of C. quinoa to deficiencies of twelve essential macro- and micronutrients across leaf and root tissues using RNA sequencing. Leaves showed the strongest responses under nitrogen, potassium, magnesium, and zinc deficiency, while roots responded more evenly across conditions. Recurring responses included suppression of photosynthesis, remodeling of translational machinery, reactive …