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Articles 119281 - 119310 of 255931

Full-Text Articles in Life Sciences

Featured Herbarium: But—The Friesner Herbarium Of Butler University, Rebecca W. Dolan Jan 2017

Featured Herbarium: But—The Friesner Herbarium Of Butler University, Rebecca W. Dolan

Scholarship and Professional Work - LAS

Feature written by Rebecca Dolan on the BUT—The Friesner Herbarium of Butler University in the Vasculum.


Evaluation Of The Brazilian Agrarian Reform Objective: Agricultural Production Yield Change, Tiffany Kwader Harbour Jan 2017

Evaluation Of The Brazilian Agrarian Reform Objective: Agricultural Production Yield Change, Tiffany Kwader Harbour

Walden Dissertations and Doctoral Studies

Brazil has an active agrarian reform policy program, publicly organized by the federal government and publicly administered at the state level by the National Institute for Colonization and Agrarian Reform. The objective of the agrarian reform policy program is to retitle unproductive and underproductive rural lands to increase agricultural production and land use. Previous agrarian reform researchers have examined quantities of land redistributed, rural technology developments, and the impact of social movements on land redistribution, but a knowledge gap remains regarding the correlation of agricultural production yields in rural municipalities before and after policy program participation. The State of Ceará …


At Risk Of Being Risky: The Relationship Between “Brain Age” Under Emotional States And Risk Preference, Marc D. Rudolph, Oscar Miranda-Domínguez, Alexandra O. Cohen, Kaitlyn Breiner, Laurence Steinberg, Richard J. Bonnie, Elizabeth S. Scott, Jason Chein, Kim Taylor-Thompson, Karla C. Fettich, Jennifer A. Richeson, Danielle V. Dellarco, Adriana Galván, B.J. Casey, Damien A. Fair Jan 2017

At Risk Of Being Risky: The Relationship Between “Brain Age” Under Emotional States And Risk Preference, Marc D. Rudolph, Oscar Miranda-Domínguez, Alexandra O. Cohen, Kaitlyn Breiner, Laurence Steinberg, Richard J. Bonnie, Elizabeth S. Scott, Jason Chein, Kim Taylor-Thompson, Karla C. Fettich, Jennifer A. Richeson, Danielle V. Dellarco, Adriana Galván, B.J. Casey, Damien A. Fair

Faculty Scholarship

Developmental differences regarding decision making are often reported in the absence of emotional stimuli and without context, failing to explain why some individuals are more likely to have a greater inclination toward risk. The current study (N = 212; 10–25y) examined the influence of emotional context on underlying functional brain connectivity over development and its impact on risk preference. Using functional imaging data in a neutral brain-state we first identify the “brain age” of a given individual then validate it with an independent measure of cortical thickness. We then show, on average, that “brain age” across the group during the …


Roles Of Community Pharmacists In Improving Oral Health Awareness In Plateau State, Northern Nigeria, Olaniyi O. Taiwo Jan 2017

Roles Of Community Pharmacists In Improving Oral Health Awareness In Plateau State, Northern Nigeria, Olaniyi O. Taiwo

Walden Dissertations and Doctoral Studies

There is poor oral health awareness in Nigeria. This is mainly attributed to limited access to correct information on oral health as well as a lack of oral health care providers. The impact of the poor oral health awareness is worse in Northern Nigeria due to the uneven distribution of oral health care workers and training facilities. The purpose of this cross-sectional study was to describe the roles of community pharmacists (CPs) in Plateau State, Nigeria as sources of oral health information. Theoretical framework for this study was the theory of planned behavior (TPB). Background knowledge and practices of oral …


Effect Of The National Accelerated Agricultural Inputs Access Subsidy Program On Fertilizer Usage And Food Production In Kakamega County, Western Kenya, Abednego Kiwia Mavuthu Jan 2017

Effect Of The National Accelerated Agricultural Inputs Access Subsidy Program On Fertilizer Usage And Food Production In Kakamega County, Western Kenya, Abednego Kiwia Mavuthu

Walden Dissertations and Doctoral Studies

Despite 25 years of concerted efforts by African governments to adopt consistent policies for increasing food production, hunger and poverty are still prevalent in the continent. Using Bernanke's conceptualization of the credit channel theory of monetary policy, the purpose of this correlational study was to investigate whether a subsidy program, the National Accelerated Agricultural Inputs Access Program (NAAIAP), affected the rates of fertilizer usage and food production in Kakamega County, Western Kenya. Purposive stratified sampling was used to select 114 participants consisting of 72 farmers in each of the 2 groups: NAAIAP beneficiaries and nonbeneficiaries. Participants completed a survey on …


Strategies For Preventing And Mitigating The Effects Of Agro-Food Supply Chain Disruptions, Everjoyce Muzvondiwa Jan 2017

Strategies For Preventing And Mitigating The Effects Of Agro-Food Supply Chain Disruptions, Everjoyce Muzvondiwa

Walden Dissertations and Doctoral Studies

Supply chain disruptions are detrimental to the performance of companies due to the associated loss of profitability and reduced sustainability. In 2016, organizations lost at least $1.2 million in a single supply chain disruption. Guided by the contingency theory of fit, the purpose of this exploratory multiple case study was to explore the strategies agribusiness managers use to prevent and mitigate the effects of disruptions in the agro-food supply chains. A total of 5 purposefully-selected agribusiness managers from Harare, Zimbabwe participated in semistructured interviews. Participants were senior agribusiness managers who implemented successful strategies for preventing and mitigating the effects of …


Subsistence Farmers' Perceptions Of Pluralistic Agriculture Extension In Northern Ghana, Amos Kwame Egyir Baah Jan 2017

Subsistence Farmers' Perceptions Of Pluralistic Agriculture Extension In Northern Ghana, Amos Kwame Egyir Baah

Walden Dissertations and Doctoral Studies

In 2013, the Ministry of Food and Agriculture of the Republic of Ghana implemented a reformed food and agriculture sector development policy (FASDEP II) to reduce poverty among the poorest subsistence farmers in the nation. These extension efforts have been unsuccessful. The purpose of this ethnographic case study was to understand the perceptions of subsistence farmers in the Savelugu-Nanton District (SND) who participated in FASDEP II on how the program had affected their ability to meet their subsistence needs. The theoretical framework of collaborative advantage was used to analyze farmers' opinions of how the decentralized, pluralistic extension policy did or …


Assessment Of A Channel Catfish Population In A Large Open River System, A. J. Blank, M. J. Hamel, Jonathan J. Spurgeon, Mark A. Pegg Jan 2017

Assessment Of A Channel Catfish Population In A Large Open River System, A. J. Blank, M. J. Hamel, Jonathan J. Spurgeon, Mark A. Pegg

School of Natural Resources: Faculty Publications

Estimates of dynamic rate functions for riverine channel catfish, Ictalurus punctatus (Rafinesque), populations are limited. The open nature and inherent difficulty in sampling riverine environments and the propensity for dispersal of channel catfish impede estimation of population variables. However, contemporary population models (i.e. robust design models) can incorporate the open nature of these systems. The purpose of this study was to determine channel catfish population abundance, survival and size structure and to characterize growth in the lower Platte River, Nebraska, USA. Annual survival estimates of adult channel catfish were 13%–49%, and channel catfish abundance estimates ranged from 8,281 to 24,261 …


Development Of The Meal Framework: A Multiliteracies Approach To Engaging Adolescents In Nutrition Education, Samantha Lee Baker Jan 2017

Development Of The Meal Framework: A Multiliteracies Approach To Engaging Adolescents In Nutrition Education, Samantha Lee Baker

Theses: Doctorates and Masters

Establishing and maintaining a healthy diet is integral in promoting optimal health, growth and development. Moreover, the food choices we make and dietary behaviours we adopt are a reflection of the multiple personal, interpersonal and environmental factors to which we are exposed. Consequently, changing food habits and dietary behaviour is complex and requires the implementation of multifaceted public health strategies. Comprehensive nutrition education provided to adolescents during their school years is one such approach.

Adolescence is a period of rapid psychological and physiological changes. At a socioemotional level, there is a decreased level of dependence on parents and a greater …


Biodiversity Monitoring Using Environmental Dna: Can It Detect All Fish Species In A Waterbody And Is It Cost Effective For Routine Monitoring?, Lia Smith Jan 2017

Biodiversity Monitoring Using Environmental Dna: Can It Detect All Fish Species In A Waterbody And Is It Cost Effective For Routine Monitoring?, Lia Smith

Theses: Doctorates and Masters

The challenges associated with environmental monitoring such as the impact on the environment and the financial costs are problems we face when trying to conserve freshwater systems around the world. The need for precise and accurate results that are cost effective is important so that we can achieve our conservation goals.

The overall aim of this study was to explore Next-Generation - metabarcoding for the detection of feral and native freshwater fish species based on the DNA shed by individual organisms into the water column. Cytochrome c oxidase I (COI) primers were developed for this study using DNA from six …


Residence Time In Coastal Canopies, Maryam Abdolahpour Jan 2017

Residence Time In Coastal Canopies, Maryam Abdolahpour

Theses: Doctorates and Masters

Aquatic canopies provide important ecosystem services such as improved water quality, oxygen flux, sediment stabilisation and trapping and recycling of nutrients. The ecological health of coastal canopies and the significant ecosystem services they provide depends largely on the continuous exchange of dissolved and particulate materials across the canopy boundaries. In coastal environments, where flow is typically wavedominated, vertical mixing is believed to be the dominant process controlling residence time and, therefore, exchange. However, experiments have shown that wave-driven flows over rough boundaries, such as canopies, generate strong onshore mean currents (75% of the orbital velocity far above the canopy) near …


Prediction Of Local Quality Of Protein Structure Models Considering Spatial Neighbors In Graphical Models., Woong Hee Shin, Xuejiao Kang, Jian Zhang, Daisuke Kihara Jan 2017

Prediction Of Local Quality Of Protein Structure Models Considering Spatial Neighbors In Graphical Models., Woong Hee Shin, Xuejiao Kang, Jian Zhang, Daisuke Kihara

Department of Biological Sciences Faculty Publications

Protein tertiary structure prediction methods have matured in recent years. However, some proteins defy accurate prediction due to factors such as inadequate template structures. While existing model quality assessment methods predict global model quality relatively well, there is substantial room for improvement in local quality assessment, i.e. assessment of the error at each residue position in a model. Local quality is a very important information for practical applications of structure models such as interpreting/designing site-directed mutagenesis of proteins. We have developed a novel local quality assessment method for protein tertiary structure models. The method, named Graph-based Model Quality assessment method …


Pengaruh Metode Uchikomi Dan Flexibility Terhadap Hasil Bantingan Pada Pejudo Daerah Istimewa Yogyakarta, Suwarli Suwarli Dec 2016

Pengaruh Metode Uchikomi Dan Flexibility Terhadap Hasil Bantingan Pada Pejudo Daerah Istimewa Yogyakarta, Suwarli Suwarli

Jurnal Keolahragaan

Penelitian bertujuan mengetahui: (1) perbedaan pengaruh antara metode uchikomi dengan menggunakan karet ban sepeda dan uchikomi jalan terhadap hasil bantingan judo, (2) perbedaan hasil bantingan antara pejudo yang memiliki flexibility tinggi dan flexibility rendah, dan (3) interaksi antara metode uchikomi dan flexibility terhadap hasil bantingan judo. Metode penelitian adalah eksperimen dengan rancangan faktorial 2 x 2. Populasi penelitian adalah pejudo D.I. Yogyakarta yang berjumlah 44 pejudo. Sampel penelitian ini 24 pejudo yang diambil dengan teknik Purposive Rondom Sampling. Data penelitian ini diperoleh melalui tes dan pengukuran. Instrumen penelitian adalah sit and reach dan Randori (dipertandingkan) selama tiga menit. Teknik …


Pengaruh Latihan Beban Dan Kekuatan Otot Terhadap Hypertrophy Otot Dan Ketebalan Lemak, Eko Sucipto, Widiyanto Widiyanto Dec 2016

Pengaruh Latihan Beban Dan Kekuatan Otot Terhadap Hypertrophy Otot Dan Ketebalan Lemak, Eko Sucipto, Widiyanto Widiyanto

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui: (1) perbedaan pengaruh antara latihan beban metode compound set dan circuit training, (2) perbedaan pengaruh kekuatan otot tinggi dan rendah,dan (3) interaksi antara metode latihan beban dan kekuatan terhadap hasil hypertrophy otot dan ketebalan lemak. Populasi dalam penelitian ini adalah 56 members yang programnya hypertrophy otot dari Fitness Centre GOR FIK UNY dan Fitness Centre Club Arena Hotel Jayakarta Yogyakarta. Sampel yang berjumlah 28 members ditentukan dengan teknik Purposive Rondom Sampling. Teknik analisis data yang digunakan dalam penelitian ini adalah Analisis Varian (ANAVA). Hasil penelitian adalah: (1) ada perbedaan pengaruh yang signifikan antara …


Pengaruh Latihan Imagery Dan Koordinasi Terhadap Keterampilan Forehand Drive Petenis Pemula, Risti Nurfadhila Dec 2016

Pengaruh Latihan Imagery Dan Koordinasi Terhadap Keterampilan Forehand Drive Petenis Pemula, Risti Nurfadhila

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui: (1) perbedaan pengaruh antara latihan imagery dengan menggunakan script dan video terhadap keterampilan forehand drive petenis pemula, (2) perbedaan keterampilan forehand drive antara petenis pemula yang memiliki koordinasi tinggi dan koordinasi rendah, (3) interaksi antara latihan imagery dan koordinasi terhadap keterampilan forehand drive petenis pemula. Metode penelitian adalah eksperimen dengan rancangan faktorial 2 x 2. Sampel penelitian adalah 32 orang petenis pemula mahasiswa PJKR FIK UNY yang mengambil mata kuliah olahraga pilihan tenis yang diambil dengan teknik Purposive Random Sampling. Seluruh data penelitian diperoleh melalui tes dan pengukuran terhadap koordinasi dengan menggunakan tes koordinasi …


Pengaruh Metode Latihan Dan Persepsi Kinestetik Terhadap Keterampilan Groundstrokes Tenis Lapangan Pada Siswa Sd, Suryono Suryono Dec 2016

Pengaruh Metode Latihan Dan Persepsi Kinestetik Terhadap Keterampilan Groundstrokes Tenis Lapangan Pada Siswa Sd, Suryono Suryono

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui: (1) Perbedaan pengaruh antara metode demonstrasi dan metode audio visual terhadap keterampilan groundstrokes tenis lapangan, (2) Perbedaan pengaruh antara persepsi kinestetik terhadap keterampilan groundstrokes tenis lapangan, dan (3) interaksi metode latihan dan persepsi kinestetik terhadap keterampilan groundstrokes. Penelitian ini merupakan penelitian eksperimen. Populasi penelitian adalah siswa SD Negeri Petinggen dan SD Negeri Terbansari yang berjumlah 75 siswa. Sampel penelitian 40 siswa ditentukan dengan teknik purposive sampling. Pengumpulan data menggunakan tes persepsi kinestetik dan keterampilan groundstrokes. Instrumen dalam penelitian ini adalah horizontal liner space test dan memantulakan bola ke dinding. Teknik analisis data …


Integrative Genomic And Transcriptomic Analysis For Pinpointing Recurrent Alterations Of Plant Homeodomain Genes And Their Clinical Significance In Breast Cancer, Huimei Yu, Yuanyuan Jiang, Lanxin Liu, Wenqi Shan, Xiaofang Chu, Zhe Yang, Zeng-Quan Yang Dec 2016

Integrative Genomic And Transcriptomic Analysis For Pinpointing Recurrent Alterations Of Plant Homeodomain Genes And Their Clinical Significance In Breast Cancer, Huimei Yu, Yuanyuan Jiang, Lanxin Liu, Wenqi Shan, Xiaofang Chu, Zhe Yang, Zeng-Quan Yang

Oncology Faculty Publications

A wide range of the epigenetic effectors that regulate chromatin modification, gene expression, genomic stability, and DNA repair contain structurally conserved domains called plant homeodomain (PHD) fingers. Alternations of several PHD finger-containing proteins (PHFs) due to genomic amplification, mutations, deletions, and translocations have been linked directly to various types of cancer. However, little is known about the genomic landscape and the clinical significance of PHFs in breast cancer. Hence, we performed a large-scale genomic and transcriptomic analysis of 98 PHF genes in breast cancer using TCGA and METABRIC datasets and correlated the recurrent alterations with clinicopathological features and survival of …


Determinants Of Integrated Soil Fertility Management Technologies Adoption By Smallholder Farmers In The Chinyanja Triangle Of Southern Africa, Powell Mponela, Lulseged Tamene, Gift Ndengu, Ruth Magreta, Job Kihara, Nelson Mango Dec 2016

Determinants Of Integrated Soil Fertility Management Technologies Adoption By Smallholder Farmers In The Chinyanja Triangle Of Southern Africa, Powell Mponela, Lulseged Tamene, Gift Ndengu, Ruth Magreta, Job Kihara, Nelson Mango

All Peer-Reviewed Publications

Integrated Soil Fertility Management (ISFM) technologies have proven to be viable options for improving land productivity and increasing yield. However, adoption of the set of complementary technologies that are required in ISFM is quite variable and studies tend to focus on single technologies. In this study we used cluster analysis to group technologies and ordered probit to determine the probability of multiple technology adoption. The result show that usage of ISFM in the Chinyanja Triangle (Southern Africa) is grouped into 3 technological sets based on complementarities. The set of nutrient dense technologies of inorganic fertiliser, compost and animal manure (ISFMset3) …


Minibrain And Wings Apart Control Organ Growth And Tissue Patterning Through Downregulation Of Capicua, Liu Yang Dec 2016

Minibrain And Wings Apart Control Organ Growth And Tissue Patterning Through Downregulation Of Capicua, Liu Yang

Graduate Doctoral Dissertations

The regulation of organ growth is a fundamental aspect of developmental biology. My work uses Drosophila as a model system to understand how the various growth regulators are coordinated. The transcriptional repressor Capicua (Cic) controls tissue patterning and restricts organ growth, and has been recently implicated in several cancers and neurodegenerative diseases. Cic has emerged as a primary sensor of signaling downstream of the receptor tyrosine kinase (RTK)/extracellular signal-regulated kinase (ERK) pathway, but how Cic activity is regulated in different cellular contexts remains poorly understood. In order to identify Cic regulators, I have used affinity purification/mass spectrometry (AP-MS) to study …


Evolution In The Deep Sea: Scales And Mechanisms Of Population Divergence, Amanda E. Glazier Dec 2016

Evolution In The Deep Sea: Scales And Mechanisms Of Population Divergence, Amanda E. Glazier

Graduate Doctoral Dissertations

The deep sea is the Earth’s largest ecosystem and harbors a unique and largely endemic fauna. Although most research has focused on the ecological mechanisms that allow coexistence, recent studies have begun to investigate how this remarkable fauna evolved.. My work quantifies geographic patterns of genetic variation and investigates potential mechanisms that shape evolution in the deep ocean.

Bathymetric genetic divergence is common in the deep sea with population structure typically decreasing with depth. The evolutionary mechanisms that underlie these patterns are poorly understood. Geographic patterns of genetic variation indicated that the protobranch bivalve Neilonella salicensis was composed of two …


Evolutionary Dynamics Of Tree Invasions: Complementing The Unified Framework For Biological Invasions, Rafael D. Zenni, Ian A. Dickie, Michael J. Wingfield, Heidi Hirsch, Casparus J. Crous, Laura A. Meyerson, Treena I. Burgess, Thalita G. Zimmermann, Metha M. Klock, Evan Siemann, Alexandra Erfmeier, Roxana Aragon, Lia Montti, Johannes J. Le Roux Dec 2016

Evolutionary Dynamics Of Tree Invasions: Complementing The Unified Framework For Biological Invasions, Rafael D. Zenni, Ian A. Dickie, Michael J. Wingfield, Heidi Hirsch, Casparus J. Crous, Laura A. Meyerson, Treena I. Burgess, Thalita G. Zimmermann, Metha M. Klock, Evan Siemann, Alexandra Erfmeier, Roxana Aragon, Lia Montti, Johannes J. Le Roux

Faculty Publications, Environmental Studies

Evolutionary processes greatly impact the outcomes of biological invasions. An extensive body of research suggests that invasive populations often undergo phenotypic and ecological divergence from their native sources. Evolution also operates at different and distinct stages during the invasion process. Thus, it is important to incorporate evolutionary change into frameworks of biological invasions because it allows us to conceptualize how these processes may facilitate or hinder invasion success. Here, we review such processes, with an emphasis on tree invasions, and place them in the context of the unified framework for biological invasions. The processes and mechanisms described are pre-introduction evolutionary …


Stability Of Cross-Feeding Polymorphisms In Microbial Communities, Ivana Gudelj, Margie Kinnersley, Peter Rashkov, Karen Schmidt, Frank Rosenzweig Dec 2016

Stability Of Cross-Feeding Polymorphisms In Microbial Communities, Ivana Gudelj, Margie Kinnersley, Peter Rashkov, Karen Schmidt, Frank Rosenzweig

Biological Sciences Faculty Publications

Cross-feeding, a relationship wherein one organism consumes metabolites excreted by another, is a ubiquitous feature of natural and clinically-relevant microbial communities and could be a key factor promoting diversity in extreme and/or nutrient-poor environments. However, it remains unclear how readily cross-feeding interactions form, and therefore our ability to predict their emergence is limited. In this paper we developed a mathematical model parameterized using data from the biochemistry and ecology of an E. coli cross-feeding laboratory system. The model accurately captures short-term dynamics of the two competitors that have been observed empirically and we use it to systematically explore the stability …


Analyzing And Modeling The Dysfunction Of Inhibitory Neurons In Alzheimer’S Disease, Carlos Perez, Jokubas Ziburkus, Ghamim Ullah Dec 2016

Analyzing And Modeling The Dysfunction Of Inhibitory Neurons In Alzheimer’S Disease, Carlos Perez, Jokubas Ziburkus, Ghamim Ullah

Physics Faculty Publications

Alzheimer’s disease (AD) is characterized by the abnormal proteolytic processing of amyloid precursor protein, resulting in increased production of a self-aggregating form of beta amyloid (Aβ). Several lines of work on AD patients and transgenic mice with high Aβ levels exhibit altered rhythmicity, aberrant neuronal network activity and hyperexcitability reflected in clusters of hyperactive neurons, and spontaneous epileptic activity. Recent studies highlight that abnormal accumulation of Aβ changes intrinsic properties of inhibitory neurons, which is one of the main reasons underlying the impaired network activity. However, specific cellular mechanisms leading to interneuronal dysfunction are not completely …


Rerspon Tanaman Hanjeli (Coix Lacryma-Jobi L.) Akibat Kombinasi Jarak Tanam Dengan Dosis Pupuk Organik Cair Di Kecamatan Rancakalong, Agus Wahyudin, Ruminta, Yuyun Yuwariah, M. Fauzi Dec 2016

Rerspon Tanaman Hanjeli (Coix Lacryma-Jobi L.) Akibat Kombinasi Jarak Tanam Dengan Dosis Pupuk Organik Cair Di Kecamatan Rancakalong, Agus Wahyudin, Ruminta, Yuyun Yuwariah, M. Fauzi

Jurnal Kultivasi

Pertambahan jumlah penduduk yang sangat besar menyebabkan kebutuhan pangan meningkat.Salah satu alternatif yang dapat dijadikan solusi adalah program diversifikasi pangan.Hanjeli adalah salah satu tanaman pangan alternatif, namun petani belum mendalami teknik budidaya tanaman ini terutama pemupukan.Oleh karena itu dilakukan suatu upaya untuk meningkatkan pertumbuhan dan hasil hanjeli dengan kombinasi jarak tanam dengan dosis pupuk organik cair.Penelitian ini bertujuan untuk memperoleh kombinasi jarak tanam dengan dosis pupuk organik cair untuk meningkatkan hasil tanaman hanjeli. Percobaan dilaksanakan di Desa Pasir Biru, Kecamatan Rancakalong, Kabupaten Sumedang pada bulan Desember 2015 sampai dengan Mei 2016. Bibit Hanjeli yang dipergunakan adalah Hanjeli Pulut aksesi 37.Rancangan …


Winner's Curse Correction And Variable Thresholding Improve Performance Of Polygenic Risk Modeling Based On Genome-Wide Association Study Summary-Level Data, Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T. Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D. Figueroa, Victoria K. Cortessis, Nuria Malats, Margaret R. Karagas Dec 2016

Winner's Curse Correction And Variable Thresholding Improve Performance Of Polygenic Risk Modeling Based On Genome-Wide Association Study Summary-Level Data, Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T. Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D. Figueroa, Victoria K. Cortessis, Nuria Malats, Margaret R. Karagas

Dartmouth Scholarship

Recent heritability analyses have indicated that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex diseases based on polygenic risk score (PRS), a simple modelling technique that can be implemented using summary-level data from the discovery samples. We herein propose modifications to improve the performance of PRS. We introduce threshold-dependent winner’s-curse adjustments for marginal association coefficients that are used to weight the single-nucleotide polymorphisms (SNPs) in PRS. Further, as a way to incorporate external functional/annotation knowledge that could identify subsets of SNPs highly enriched for associations, we propose variable thresholds for SNPs selection. We applied …


Pemanfaatan Empat Isolat Trichoderma Sp. Untuk Mengendalikan Penyakit Akar Gada Pada Tanaman Caisin, Melinda Yudha, L. Soesanto, E. Mugiastuti Dec 2016

Pemanfaatan Empat Isolat Trichoderma Sp. Untuk Mengendalikan Penyakit Akar Gada Pada Tanaman Caisin, Melinda Yudha, L. Soesanto, E. Mugiastuti

Jurnal Kultivasi

Penelitian ini bertujuan untuk mengetahui pengaruh aplikasi empat isolat Trichoderma sp. dalam mengendalikan penyakit akar gada serta pengaruhnya terhadap pertumbuhan dan hasil tanaman caisin. Penelitian ini dilaksanakan di lahan percobaan Fakultas Pertanian, Universitas Jenderal Soedirman, mulai Mei 2016 sampai bulan Juni 2016. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK), yang terdiri atas 7 perlakuan dan 4 ulangan. Perlakuan terdiri atas, kontrol diinokulasikan P. brassicae, kontrol tidak diinokulasikan P. brassicae, Trichoderma sp. isolat jahe, Trichoderma sp. isolat bawang, Trichoderma sp. isolat pisang, Trichoderma sp. isolat nenas, dan fungisida berbahan aktif Azoksistrobin dan Difenokonazol. Variabel yang diamati adalah masa inkubasi, intensitas penyakit …


Aplikasi Pupuk Organik Cair Pada Tanaman Kentang Varietas Granola Di Dataran Medium, Hidayati Karamina, Wahyu Fikrinda Dec 2016

Aplikasi Pupuk Organik Cair Pada Tanaman Kentang Varietas Granola Di Dataran Medium, Hidayati Karamina, Wahyu Fikrinda

Jurnal Kultivasi

Kentang merupakan tanaman semusim dengan berbentuk menyemak dan memiliki sifat menjalar. Salah satu alternative upaya untuk meningkatkan hasil produktivitas kentang yaitu adalah penanaman kentang pada dataran medium. Tujuan dari penelitian ini adalah untuk menentukan jenis jenis dan takaran pupuk organik cair yang optimum dalam meningkatkan produksi kentang di dataran medium sehingga dari efektivitas itulah diharapkan pertumbuhan dan produktivitas kentang mampu optimal. Penelitian ini menggunakan Rancangan Acak Kelompok dengan 3 ulangan dengan 11 perlakuan. Hasil penelitian menunjukkan bahwa pupuk organik cair BIO-As dengan dosis 25 ml.l -1 mampu meningkatkan pertumbuhan tinggi tanaman, jumlah daun, jumlah batang, dan bobot total tanaman kentang. …


Aplikasi Pupuk Organik Terhadap Hasil Kacang Hijau (Vigna Radiate L.) Di Ultisol, Ida Widiyawati, T. Harjoso, T. T. Taufik Dec 2016

Aplikasi Pupuk Organik Terhadap Hasil Kacang Hijau (Vigna Radiate L.) Di Ultisol, Ida Widiyawati, T. Harjoso, T. T. Taufik

Jurnal Kultivasi

Permasalahan budidaya kacang hijau di Indonesia adalah produktivitas yang masih rendah dan lahan budidaya yang terbatas, sehingga dapat diatasi dengan mengoptimalkan lahan marginal seperti tanah ultisol untuk kegiatan budidaya kacang hijau. Tujuan pene-litian ini adalah untuk mengetahui varietas kacang hijau dan jenis pupuk organik yang mampu menghasilkan produksi tinggi di tanah ultisol. Penelitian dilakukan menggunakan polibag di Screen House, Fakultas Pertanian, Universitas Jenderal Soedirman pada bulan Juli-September 2015. Penelitian menggunakan Rancangan Acak Kelompok Lengkap (RAKL) dengan dua faktor. Faktor pertama adalah varietas kacang hijau yang terdiri atas tiga varietas, yaitu Vima 1, Betet, dan Murai. Faktor kedua adalah jenis pupuk, …


Pertumbuhan Eksplan Meristem Bawang Putih (Allium Sativum L.) Kultivar Tawangmangu Pada Berbagai Komposisi Kinetin Dan Ga3 In Vitro, Y. Sholihin, Erni Suminar, Wieny Heriliya Rizky, G. G. Pitaloka Dec 2016

Pertumbuhan Eksplan Meristem Bawang Putih (Allium Sativum L.) Kultivar Tawangmangu Pada Berbagai Komposisi Kinetin Dan Ga3 In Vitro, Y. Sholihin, Erni Suminar, Wieny Heriliya Rizky, G. G. Pitaloka

Jurnal Kultivasi

Bawang putih merupakan komoditas penting di Indonesia. Indonesia merupakan negara terbesar pengimpor bawang putih. Permasalahan yang dihadapi dalam teknik produksi benih secara konvensional menjadi salah satu faktor pembatas tidak optimalnya pengembangan dan penyebaran benih tersebut. Produksi benih in vitro dapat dijadikan sebagai metode alternatif dalam perbanyakan benih sumber kultivar unggul. Penelitian ini bertujuanuntuk mendapatkan komposisi kinetin dan GA3 terbaik pada media dasar MS untuk regenerasi eksplan meristemsecara in vitro.Penelitian dilaksanakan di Laboratorium Kultur JaringanBalai Pengembangan Benih Hortikultura dan Aneka Tanaman Pasir Banteng, Kecamatan Jatinangor, Kabupaten Sumedang, Provinsi Jawa Barat, yang berlangsung dari bulan April hingga Juli 2015. Eksplan yang digunakan …


Pertumbuhan Dan Hasil Padi Gogo Hubungannya Dengan Kandungan Prolin Dan 2-Acetyl-1-Pyrroline Pada Kondisi Kadar Air Tanah Berbeda, A. Y. Rahayu, T. A.D. Haryanto, S. N. Iftitah Dec 2016

Pertumbuhan Dan Hasil Padi Gogo Hubungannya Dengan Kandungan Prolin Dan 2-Acetyl-1-Pyrroline Pada Kondisi Kadar Air Tanah Berbeda, A. Y. Rahayu, T. A.D. Haryanto, S. N. Iftitah

Jurnal Kultivasi

Penelitian ini bertujuan untuk mengetahui respons varietas padi gogo pada kadar air tanah berbeda terhadap pertumbuhan, hasil dan kandungan prolin dan 2-acetyl-1-pyrroline biji. Penelitian dilaksanakan di Universitas Tidar Magelang mulai bulan September 2012 sampai dengan Maret 2013. Percobaan menggunakan Rancangan Acak Kelompok Lengkap terdiri atas dua faktor yaitu varietas padi gogo (Inpago Unsoed-1, galur JSPGA 136, varietas Situ-bagendit (non-aromatik) dan varietas Mentik Wangi) dan tingkat kadar air tanah (100 % kapasitas lapang dan 50 % kapasitas lapang). Variabel pengamatan meliputi: tinggi tanaman (cm), jumlah anakan total per rumpun (batang), jumlah anakan produktif (batang), total panjang akar (m), umur berbunga (hst), …