Memories Of Genetic Testing: From My Mom To Angelina Jolie, 2013 University of San Diego
Memories Of Genetic Testing: From My Mom To Angelina Jolie, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
A Key New Ally In The Search For Huntington’S Disease Treatments, 2013 University of San Diego
A Key New Ally In The Search For Huntington’S Disease Treatments, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Characterizing Stomatin-Like Protein 2 And Its Role In Neuron Survival, 2013 The University of Western Ontario
Characterizing Stomatin-Like Protein 2 And Its Role In Neuron Survival, Lisa A. Foris
Electronic Thesis and Dissertation Repository
Stomatin-like Protein 2 (SLP-2) has been identified as a stress-inducible transcript and has been shown to interact with and stabilize mitochondrial proteins. Since mitochondria are critical for neuronal function, we hypothesized that SLP-2 regulates neuron survival in response to stressful stimuli. A conditional SLP-2 knockout mouse (deletion) and the SN56 cell line (upregulation) were employed to study the role of SLP-2 in mitochondrial dynamics and neuron survival. SLP-2 deficient primary cortical neurons displayed significantly decreased levels of various mitochondrial respiratory chain proteins, indicating SLP-2 contributes to maintenance of mitochondrial membrane integrity. SLP-2 was up-regulated in response to oxidative stress and …
Feeling The Hope, 2013 University of San Diego
Feeling The Hope, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Quickening The Pace Towards A Huntington’S Disease Gene-Silencing Clinical Trials: Pharma Giant Roche, Isis Enter Partnership, 2013 University of San Diego
Quickening The Pace Towards A Huntington’S Disease Gene-Silencing Clinical Trials: Pharma Giant Roche, Isis Enter Partnership, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Cerebral Palsy: Overcoming Disability, 2013 Cedarville University
Cerebral Palsy: Overcoming Disability, David A. Banz
The Research and Scholarship Symposium (2013-2019)
No abstract provided.
Intensive Goal-Directed Treatments In Enriched Environments Augments Patient Outcomes Post-Stroke, 2013 Rehabilitation Institute of Chicago
Intensive Goal-Directed Treatments In Enriched Environments Augments Patient Outcomes Post-Stroke, Blake A. Kandah, Michael A. Klonowski, Ryan M. Pelo, Nicole M. Williams, Raquel V. Santiago, Christopher K. Thompson, Kristan A. Leech, Carey L. Holleran, Abigail L. Leddy, T. George Hornby
GW Research Days 2013
Objective: Previous research indicates that patients post-stroke, average 400-800 steps within physical therapy sessions and demonstrate heart rate values of 24-35% of HR Max. This dosage and intensity is inadequate to promote neuroplastic changes and maximize recovery. The goal of this study was to quantify and examine the amount of high-intensity stepping practice that was delivered within an Acute Inpatient Rehabilitation (AIR) setting for individuals with sub-acute stroke.
Methods: 14 patients with a diagnosis of sub-acute stroke were admitted to AIR. Standardized outcomes included the 6-Minute Walk Test (6MWT), 10-Meter Walk Test (10MWT), the Berg Balance Scale (BBS) and the …
Brazil’S Big Place On The Huntington’S Disease Map, 2013 University of San Diego
Brazil’S Big Place On The Huntington’S Disease Map, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Norepinephrine Involvement In The Intermittent Swim Stress-Induced Deficit In Spatial Learning And Memory, 2013 University of New Hampshire - Main Campus
Norepinephrine Involvement In The Intermittent Swim Stress-Induced Deficit In Spatial Learning And Memory, Emily Elgert
Honors Theses and Capstones
Learning and memory impairments are often caused by stress disorders including depression. The present study investigated the involvement of norepinephrine in the swim stress-induced deficits of spatial learning and memory. Exposure to intermittent swim stress (ISS) followed by learning and memory tests in the Morris water maze (MWM) were used to investigate this relationship. The ISS paradigm consists of intermittent exposure to cold water, producing stress responses in rats. Reboxetine, a norepinephrine selective reuptake inhibitor (NSRI), was employed to investigate whether this compound reverses the ISS-induced deficit. In other words, rats exposed to the ISS, were hypothesized to experience impaired …
Fibromyalgia Syndrome: A Pathoneurological Basis Of Disease, 2013 Liberty University
Fibromyalgia Syndrome: A Pathoneurological Basis Of Disease, Alex D. Hamilton
Senior Honors Theses
Fibromyalgia (also known as fibromyalgia syndrome, or FMS) is a condition which causes its victims to suffer a wide range of symptoms, most notably chronic musculoskeletal pain. Although the causes of fibromyalgia remain unknown, recent advances help elucidate the underlying pathophysiologies of this condition, and show that it is likely not a musculoskeletal condition, but rather a pathoneurological condition.
Big Decisions While Facing The Threat Of Huntington's Disease, 2013 University of San Diego
Big Decisions While Facing The Threat Of Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
The Brain Activity Map Project: Short- And Long-Term Prospects For Huntington's Disease Research, 2013 University of San Diego
The Brain Activity Map Project: Short- And Long-Term Prospects For Huntington's Disease Research, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
The Return Of The Huntington’S Whirlwind, 2013 University of San Diego
The Return Of The Huntington’S Whirlwind, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Diagnosis And Evaluation Of Peripheral Neuropathies, 2013 Lehigh Valley Health Network
Diagnosis And Evaluation Of Peripheral Neuropathies, Jay D. Varrato Do
Neurology Update for the Non-Neurologist
No abstract provided.
Diagnosis And Treatment Options For Multiple Sclerosis, 2013 Lehigh Valley Health Network
Diagnosis And Treatment Options For Multiple Sclerosis, Gary Clauser Md
Neurology Update for the Non-Neurologist
No abstract provided.
Current Standards For Treatment Of Stroke: Management Of Acute Ischemic Stroke, 2013 Lehigh Valley Health Network
Current Standards For Treatment Of Stroke: Management Of Acute Ischemic Stroke, John E. Castaldo Md
Neurology Update for the Non-Neurologist
No abstract provided.
Diagnosis, Evaluation And Treatments For Dementia, 2013 Lehigh Valley Health Network
Diagnosis, Evaluation And Treatments For Dementia, John W. Margraf Md
Neurology Update for the Non-Neurologist
No abstract provided.
Treatment Options For Seizures: Practical Points In Epilepsy Management, 2013 Lehigh Valley Health Network
Treatment Options For Seizures: Practical Points In Epilepsy Management, Soraya E. Jiménez Md
Neurology Update for the Non-Neurologist
No abstract provided.
Diagnosis, Assessment And Evaluation For Seizures, 2013 Lehigh Valley Health Network
Diagnosis, Assessment And Evaluation For Seizures, John W. Margraf Md
Neurology Update for the Non-Neurologist
No abstract provided.
Special Populations And Considerations In Migraine Therapy, 2013 Lehigh Valley Health Network
Special Populations And Considerations In Migraine Therapy, Gary Clauser Md
Neurology Update for the Non-Neurologist
No abstract provided.