Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells,
2023
Noorda College of Osteopathic Medicine
Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Testing Extraction Of Dna From Lipid-Rich Tissues Using Various Reagents And Commercially Available Kits,
2023
Noorda College of Osteopathic Medicine
Testing Extraction Of Dna From Lipid-Rich Tissues Using Various Reagents And Commercially Available Kits, Ryan V. Powers, Walker C. Kay, Jonathon C. Reynolds, Nathaniel E. Hill, Cole J. Farnsworth, Molly E. Henley, Alfred B. Amendolara, Noah D. Boekweg, John A. Kriak, Kyle B. Bills, David W. Sant
Annual Research Symposium
No abstract provided.
Emotional Eating And Diet-Related Self-Efficacy, Motivation, And Norms In Adolescents,
2023
University of Southern California
Emotional Eating And Diet-Related Self-Efficacy, Motivation, And Norms In Adolescents, Tyler Mason, Rachel Dayag, Anna Dolgon-Krutolow, Kathy Lam, Diana Zhang, Vivienne Hazzard, Kathryn Smith
Health Behavior Research
The objective of the current study was to examine the association between emotional eating and self-efficacy, motivation, and social norms for consumption of fruits and vegetables (F/V) and energy-dense, nutrient-poor (EDNP) foods and beverages, as well as interactions with body mass index-z score (BMI-z). Adolescents completed self-report measures of demographics, emotional eating, and dietary health behavior theory constructs. Emotional eating was associated with lower self-efficacy for consumption of F/V and for limiting EDNP foods/beverages; greater motivation for limiting of EDNP foods/beverages; lower social norms for consumption of F/V; and greater social norms for consumption of EDNP foods/beverages. There were no …
Progressive Acceleration Of Insulin Exposure Over 7 Days Of Infusion Set Wear,
2022
Thomas Jefferson University
Progressive Acceleration Of Insulin Exposure Over 7 Days Of Infusion Set Wear, Jasmin R. Kastner, Timothy S. Bailey, Poul Strange, Leon Shi, Keith A. Oberg, Paul J. Strasma, Jeffrey I. Joseph, Douglas B. Muchmore
Department of Anesthesiology Faculty Papers
Insulin exposure varies over 3 days of insulin infusion set (IIS) wear making day-to-day insulin dosing challenging for people with diabetes (PWD). Here we report insulin pharmacodynamic (PD) and pharmacokinetic (PK) data extending these observations to 7 days of IIS wear. PWD (A1C ≤8.5%, C-peptide tmax (P < 0.001), Cmax (P < 0.05), and mean residence time (P < 0.0001). Area under the insulin concentration curve (AUC0–300) declined by ∼24% from days 0 to 7 (P < 0.05). These results confirm/extend previous observations showing progressive acceleration of insulin exposure over IIS wear time. This may have implications for PWD and designers of closed-loop algorithms, although larger studies are necessary to confirm this. The study was registered in clinicaltrials.gov (NCT04398030).
Weekly Telehealth Weigh-In For Bmi Reduction,
2022
University of St. Augustine for Health Sciences
Weekly Telehealth Weigh-In For Bmi Reduction, Kelly Ahmad
Student Scholarly Projects
Practice Problem: The citizens of the United States are known for being overweight or obese. The Centers for Disease Control and Prevention (CDC, 2021) reported that approximately 74% of adults are either overweight or obese. PICOT: The PICOT question that guided this project was In overweight adults (P), does telemonitoring weekly for counseling and weigh-in (I) compared to current practice (C) decrease BMI over an 8-week period of time (T)? Evidence: The citizens of the United States are known for being overweight or obese. The Centers for Disease Control and Prevention (CDC, 2021) reported that approximately 74% of …
Bidirectional Associations Between Daytime Napping Duration And Metabolic Syndrome: A Nationally Representative Cohort Study,
2022
Edith Cowan University
Bidirectional Associations Between Daytime Napping Duration And Metabolic Syndrome: A Nationally Representative Cohort Study, Jinqi Wang, Zhiyuan Wu, Xiaohan Jin, Rui Jin, Ze Han, Haiping Zhang, Zongkai Xu, Yue Liu, Xiuhua Guo, Lixin Tao
Research outputs 2022 to 2026
Background: We aimed to examine the bidirectional associations between daytime napping duration and metabolic syndrome (MetS). Methods: Using data from the China Health and Retirement Longitudinal Study from 2011 to 2015, modified Poisson regression models were performed to explore the longitudinal associations of baseline napping duration with the occurrence and remission of MetS. Generalized estimating equation was conducted to explore the association between baseline MetS status with subsequent changes in daytime napping duration. Cross-lagged panel analysis was performed to further verify their bidirectional relationships. Results: During the four-year follow-up, among 5041 participants without MetS at baseline, extended naps were significantly …
Western Diet-Like Culture Conditions And Oxidative Stress On A Cell Model Of Non-Alcoholic Fatty Liver Disease,
2022
The University of Western Ontario
Western Diet-Like Culture Conditions And Oxidative Stress On A Cell Model Of Non-Alcoholic Fatty Liver Disease, Celina M. Valvano
Electronic Thesis and Dissertation Repository
Non-alcoholic fatty liver disease (NAFLD) is a major health burden in the Western world, as the Western diet (WD) appears to be the driving force of this disease. However, the individual contributions of the diet and the impacts of their individual metabolism are currently ill-defined. This study used HepG2 cells to understand the impact of the individual components of WD in early NAFLD development under basal insulin levels. Specifically, nutrient-induced changes in reactive oxygen species (ROS) and signaling pathways, such as sterol regulatory element binding proteins (SREBPs), were examined to identify the root cause of steatosis development. High-fat and WD-exposed …
Eating Disorders In Men: A Comprehensive Summary,
2022
SCHOOL OF PHILOSOPHY, PSYCHOLOGY AND LANGUAGE SCIENCES, UNIVERSITY OF EDINBURGH, UK
Eating Disorders In Men: A Comprehensive Summary, Connor James Spratt, Liam Alexander Mackenzie Myles, Emanuele Maria Merlo
Journal of Mind and Medical Sciences
Eating disorders (EDs) have detrimental effects on an individual’s physical and mental health, along with significant interpersonal, social and economic effects. Furthermore, men who are suffering with an ED face unique challenges with this. Men suffering with EDs have historically received little attention within ED research, diagnosis and intervention. However, the number of men suffering with these issues is significant and growing. Understanding of EDs tend to ignore male experiences, meaning many are left to suffer in silence until the ED has developed to a critical point. However, many now recognize the need to understand the issues facing men suffering …
Wellness Review 2022, Part 1,
2022
University of Louisville
Wellness Review 2022, Part 1, Martin Huecker, Brian A. Ferguson, Jacob Shreffler
Journal of Wellness
Introduction: This article represents the first of a two-part assessment of 2022 literature addressing wellness in healthcare professionals published from January 1, 2022 to June 30, 2022.
Methods: Three editors conducted a similar keyword search in Pubmed, also adding manually curated articles. Focusing chiefly on clinical trials and other prospective research, we settled on a final 25 significant papers focusing on wellness in medical professionals to include in this review.
Literature Review: Recent literature into HCW wellness continues to describe burnout factors and COVID-19 impact, but includes more resilience-targeting interventions and systematic reviews of trials seeking bolstering of well-being. Subsections …
The Reported External Traumas Among People With Diabetes-Related Foot Ulcers And Their Outcomes: A Systematic Review Of Case Reports,
2022
Edith Cowan University
The Reported External Traumas Among People With Diabetes-Related Foot Ulcers And Their Outcomes: A Systematic Review Of Case Reports, Ma'en Zaid Abu-Qamar, Vivien Kemp, Lisa Whitehead
Research outputs 2022 to 2026
The objective of this systematic review was to collate evidence published in case reports on the reported origins of external traumas that contribute to the development of diabetic foot ulcers and their outcomes. The review also aimed to suggest reporting criteria for external traumas contributing to the development of diabetic foot ulcers. The search strategy led to the identification of 1224 articles across six electronic databases. Additional articles were also sourced from other electronic platforms (Google scholar) and the reference lists of the included case reports. Ninety-four articles met the inclusion criteria and were published between 1989 and 2020. The …
Vitamin C Deficiency In A Food Insecure Patient: A Rare Case Report,
2022
Drexel University College of Medicine, Philadelphia, PA
Vitamin C Deficiency In A Food Insecure Patient: A Rare Case Report, Gersham J. Rainone, Tatiana J. Han, Muhammed Rahim, Gregory J. Pirolli, Alina Popa, Jayaram Thimmapuram
Transformative Medicine (T-Med)
Introduction: Scurvy is rarely seen in developed countries and is characterized by deficiency of vitamin C, which can lead to symptoms including wound impairment, bleeding manifestations, and loss of teeth. Case Description: We present a case of a 53-year-old male with a right knee hemarthrosis after a fall. The patient also noted progressively enlarging spontaneous hematomas, denying any recent trauma except for the fall to the knee. He denied family history of bleeding and clotting disorders and endorsed aspirin use in the setting of a prior stroke. He actively resided at a local shelter with limited means of transportation for …
Fenotipo Delgado Metabólicamente Obeso Como Riesgo De Hipertensión Arterial En Peruanos. Una Cohorte De 5 Años,
2022
Universidad Cientifica del Sur
Fenotipo Delgado Metabólicamente Obeso Como Riesgo De Hipertensión Arterial En Peruanos. Una Cohorte De 5 Años, Jamee Guerra Valencia, Jenny Torres-Malca, Jesús Enrique Talavera, Fiorella Zuzunaga-Montoya, Jhony De La Cruz-Vargas, Víctor Juan Vera-Ponce
AMNET XIX Conferencia Internacional
No abstract provided.
Factores Asociados A La No Realización Del Cribado De Diabetes Mellitus. Análisis De La Encuesta Demográfica Y De Salud Familiar-2020,
2022
Universidad Ricardo Palma
Factores Asociados A La No Realización Del Cribado De Diabetes Mellitus. Análisis De La Encuesta Demográfica Y De Salud Familiar-2020, Fiorella Trujillo, Victor Juan Vera-Ponce, Jenny Raquel Torres-Malca, Fiorella Zuzunaga-Montoya, Jamee Guerra, Jhonny De La Cruz-Vargas
AMNET XIX Conferencia Internacional
No abstract provided.
Stones, Bones, And Groans With Cancerous Overtones - A Rare Case Of Diffuse Large B Cell Lymphoma Presenting As Hypercalcemia,
2022
Drexel University
Stones, Bones, And Groans With Cancerous Overtones - A Rare Case Of Diffuse Large B Cell Lymphoma Presenting As Hypercalcemia, Evan Becker, Caitlyn Moss, Steve Chung
Advances in Clinical Medical Research and Healthcare Delivery
Diffuse large B cell lymphoma (DLBCL) is a type of non-Hodgkin lymphoma that can present in a variety of ways including fever, weight loss, weakness, and drenching night sweats. Uncommonly, hypercalcemia of malignancy can be associated with DLBCL through multiple mechanisms that include synthesis of parathyroid hormone related peptide (PTHrP) or elevated calcitriol levels. It is estimated that hypercalcemia in the setting of DLBCL is present in 18% of newly diagnosed cases. This report details a case of an 80-year-old man with history of chronic anemia and CKD stage 3b that presented with weakness, decreased oral intake, and self-reported weight …
Relationship Between 25-Hydroxyvitamin D And Interleukin-6 With Frailty In Hospitalized Elderly Patients With Chronic Disease In The Stable Phase,
2022
1.School of Medicine,Kunming University of Science and Technology,Kunming 650500,China
2.Department of Geriatrics,the First People's Hospital of Yunnan Province,Kunming 650032,China
Relationship Between 25-Hydroxyvitamin D And Interleukin-6 With Frailty In Hospitalized Elderly Patients With Chronic Disease In The Stable Phase, Jingrong Dai, Jie Li, Xu He, Yang Li, Yan Li
General Practice in China
Background Frailty-related issue is increasingly prominent with the acceleration of aging in China.However, domestic research on frailty is still in its infancy characterized by non-objective diagnosis basis, unclear pathogenesis and imperfect interventions.Objective To investigate the correlation of 25-hydroxyvitamin D and interleukin-6 with frailty in elderly patients with chronic disease in the stable phase,so asto explore objective diagnostic basis and new interventions for frailty. Methods A total of 152 inpatients (≥ 60 years old) with chronic disease in the stable phase were recruited from Department of Geriatrics,the First People's Hospital of Yunnan Province(hereinafter referred to as “the department of the hospital”) …
Sex-Specific Correlations Of Fracture Risk With Nutritional Status, Body Composition And Balance Condition In Parkinson's Disease Patients,
2022
Department of Neurology,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,China
Sex-Specific Correlations Of Fracture Risk With Nutritional Status, Body Composition And Balance Condition In Parkinson's Disease Patients, Xiaohui Xu, Junmei Tian, Weiwei Cai, Yongfei Zhao, Yupeng Wang, Chao Liu, Zhihui Duan
General Practice in China
Background Sufficient attention has not been paid to malnutrition,one of the non-motor symptoms of Parkinson's disease (PD),for a long time. Malnutrition,sarcopenia and balance disorders increase fracture risk in PD patients. Currently,the research in this field is relatively rare in China. Objective To examine sex-specific correlations of nutritional status,bodycomposition and balance condition with fracture risk in PD patients.Methods A total of 68 PD patients (37 males and 31 females)treated in Luoyang Central Hospital Affiliated to Zhengzhou University from December 2018 to December 2020 were enrolled,and their general data were collected. Then,the 10-year risks for major osteoporotic fractures (MOF) and hip fractures …
Prevalence Survey Of Overweight, Obesity And Central Obesity Among Community-Living Residents In Beijing's Pinggu District,
2022
The First Clinical Medical College,Nanjing Medical University,Nanjing 211166,China
Prevalence Survey Of Overweight, Obesity And Central Obesity Among Community-Living Residents In Beijing's Pinggu District, Zihou Zhao, Xiangshuang Kong, Lianying Wang, Guangxia Guo, Yufeng Li
General Practice in China
Background Overweight and obesity have been proved to be important risk factors of chronic diseases such as diabetes,hypertension,arteriosclerotic cardiovascular disease and tumor. According to the latest data,the total number of overweight and obesity population in China is close to 1/4 of the total population. Timely knowing the prevalence of overweight and obesity in different regions may provide theoretical basis for formulating prevention and control strategies of obesity and other chronic diseases.Objective To investigate the prevalence of overweight,obesity and central obesity in communityliving residents in Pinggu District of Beijing,to provide a science-based strategy for local control of obesity-related diseases as early …
Prenatal Choline Supplementation During Maternal Obesity Alters Offspring Response To Western Diets,
2022
The Graduate Center, City University of New York
Prenatal Choline Supplementation During Maternal Obesity Alters Offspring Response To Western Diets, Hunter W. Korsmo
Dissertations, Theses, and Capstone Projects
Maternal obesity has led to an increase in adverse offspring developmental outcomes and a greater risk for long-term metabolic diseases. Choline, a semi-essential nutrient, can be incorporated into phosphatidylcholine (PC) as well as sphingomyelin (SM) and donate its labile methyl group for the remethylation of homocysteine after choline is oxidized to betaine. Prenatal choline insufficiency has been related to maternal obesity and metabolic diseases, such as metabolic associated fatty liver disease (MAFLD). Choline may interact with maternal obesity to influence the programming offspring.
Chapter 1 presents an introduction of choline and the various clinical outcomes associated with choline supplementation during …
Efficacy Of Various Interventions For Achieving Target Hba1c Levels For Patients With Type Ii Diabetes Mellitus And On Exogenous Insulin,
2022
University of Tennessee Health Science Center
Efficacy Of Various Interventions For Achieving Target Hba1c Levels For Patients With Type Ii Diabetes Mellitus And On Exogenous Insulin, Caitlin S. Welch, Archie Troxel
Longitudinal Scholar's Project
Objective: To learn the rates at which patients at UT Family Medicine–St. Francis (UTFM–SF) with type II diabetes mellitus are being prescribed recommended medications—namely metformin, sodium-glucose cotransporter 2 (SGLT2) inhibitors, and glucagon-like peptide 1 receptor agonists (GLP1RAs)—whether these rates correspond to the severity of hyperglycemia (as indicated by HbA1C level). A secondary goal of the study was to investigate if HbA1C levels are being checked at recommended intervals.
Methods: A retrospective chart review was conducted using records of patients seen at the clinic in the previous four years between the ages of 18 and 65 who had visits with ICD …
The Effect Of Type 1 Diabetes On The Metabolic Response To Exercise,
2022
Western University
The Effect Of Type 1 Diabetes On The Metabolic Response To Exercise, Theres Tijo
Undergraduate Student Research Internships Conference
Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder that results in insufficient endogenous insulin production. Regular exercise has numerous health benefits for individuals with T1DM, however, most insulin-dependent diabetics avoid physical activity due to the fear of exercise-induced hypoglycemia (low blood glucose/BG).
The risk of hypoglycemia in this population may be partly due to lower liver glycogen stores which is a major source of blood glucose during exercise. However, the mechanism that leads to lower glycogen stores in T1DM is unknown.
The purpose of this study was to determine the effect of an acute bout of moderate-intensity aerobic exercise …
