Albany State University, Georgia
Morehead State University
Sacred Heart University
University of Pennsylvania
Population Council
Hepatitis Screening,
2023
Otterbein University
Hepatitis Screening, Kathryn Bland
Masters Theses/Capstone Projects
Project on hepatitis screening.
Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations,
2023
Harvard University
Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations, Nicole Rychagov
CODEE Journal
An inquiry-based project that discusses immune system dynamics during HIV infection using differential equations is presented. The complex interactions between healthy T-cells, latently infected T-cells, actively infected T-cells, and the HIV virus are modeled using four nonlinear differential equations. The model is adapted to simulate long term HIV dynamics, including the AIDS state, and is used to simulate the long term effects of the traditional antiretroviral therapy (ART). The model is also used to test viral rebound over time of combined application of ART and a new drug that blocks the reactivation of the viral genome in the infected cells …
Debunking Old Evolution Theories, Proposing New One (Near Neutral Balanced Selection Theory/Nnbst) Using Sars Cov 2 Genomic Data,
2023
Rowan University
Debunking Old Evolution Theories, Proposing New One (Near Neutral Balanced Selection Theory/Nnbst) Using Sars Cov 2 Genomic Data, Chun Wu
Faculty Scholarship for the College of Science & Mathematics
The COVID 19 pandemic has caused 672 million infections and 6 million deaths understanding the molecular evolution of this virus is critical to ending this pandemic • The SARS CoV 2 genome exhibits a time independent, constant genomic substitution rate ( despite increasing vaccinations and infected human cases (Figure 1 A) • Out of the three main evolutionary theories S electionist Theory/ST, Kimura’s Neutral Theory/KNT, Ohta’s Nearly Neutral Theory/ONNT), the SARS CoV 2 GSR seemingly follows KNT but this does not explain the critical intervention by vaccines and therapeutic drugs on the evolution of this virus I n this study …
Potential Of Dietary Flavonoids In The Prevention And Therapy Of Covid-19 : Focusing In Mast Cell - Calcium Ion Channel Axis,
2023
Universitas Indonesia
Potential Of Dietary Flavonoids In The Prevention And Therapy Of Covid-19 : Focusing In Mast Cell - Calcium Ion Channel Axis, Aryo Tedjo
Indonesian Journal of Medical Chemistry and Bioinformatics
Syndrome Acute Respiratory Syndrome Corona Virus-2 (SARS COV2) is the virus that causes the COVID19 disease and has caused more than 4 million deaths worldwide. This virus infects the host cell through the interaction between the virus’s glycoprotein S molecule with the ACE2 which is the virus receptor, binding, undergoes membrane fusion and enters the cell and replicates in it. Currently, several strategies used in developing anti-viral compounds are targeting compounds that play a role in the process of entering the virus into host cells such as ACE2, S glycoprotein, and TMPRSS2, while some target main proteases such as RNA …
Virtual And In Vitro Screening Of Natural Products Identifies Indole And Benzene Derivatives As Inhibitors Of Sars-Cov-2 Main Protease (MPro),
2023
Chapman University
Virtual And In Vitro Screening Of Natural Products Identifies Indole And Benzene Derivatives As Inhibitors Of Sars-Cov-2 Main Protease (MPro), Dony Ang, Riley Kendall, Hagop S. Atamian
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
The rapid spread of the coronavirus disease 2019 (COVID-19) resulted in serious health, social, and economic consequences. While the development of effective vaccines substantially reduced the severity of symptoms and the associated deaths, we still urgently need effective drugs to further reduce the number of casualties associated with SARS-CoV-2 infections. Machine learning methods both improved and sped up all the different stages of the drug discovery processes by performing complex analyses with enormous datasets. Natural products (NPs) have been used for treating diseases and infections for thousands of years and represent a valuable resource for drug discovery when combined with …
Factors Influencing The Use Of Multiple Hiv Prevention Services Among Transport Workers In A City In Southwestern Uganda,
2023
Bishop Stuart University, Mbarara, Uganda
Factors Influencing The Use Of Multiple Hiv Prevention Services Among Transport Workers In A City In Southwestern Uganda, Benjamin Betunga, Phionah Atuhaire, Catherine Nakasiita, Christa Kanyamuneza, Proscovia Namiiro, Joseph Tugume, Matovu Hairat, Ahmed Sarki, Benedicto Mugabi, Birungi Lilian, Richard Mugisha Richard Mugisha, Edward Kumakech, John Baptist Asiimwe
School of Nursing & Midwifery, East Africa
The use of multiple HIV prevention services has been found to decrease the risk of acquiring HIV when tailored to individuals at risk of HIV exposure, including transport workers. Therefore, we assessed the uptake of multiple HIV prevention services (≥2) and associated factors among transport workers in a city in Southwestern Uganda. This cross-sectional study comprised motorcycle taxi riders, motor vehicle and truck drivers, aged 18 to 55 years who were selected and responded to an interviewer-administered questionnaire, between November 2021 and February 2022. Data was analyzed using descriptive statistical and modified Poisson regression analyses. Out of 420 participants, 97.6% …
Performance Of A Sars-Cov-2 Rt-Pcr Assay With Non-Traditional Specimen Types,
2023
University of Louisville
Performance Of A Sars-Cov-2 Rt-Pcr Assay With Non-Traditional Specimen Types, Subathra Marimuthu, Holly Aliesky, Heather Ness, Daniya Sheikh, Sathya Rashmit, Dawn Balcom, Leslie A. Wolf
The University of Louisville Journal of Respiratory Infections
During the first two years of the coronavirus disease 2019 (COVID-19) pandemic, nasopharyngeal (NP) specimens were the gold standard for clinical diagnostic testing. As information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the pandemic continued to be shared, it was clear that the virus could be detected in other specimen types during an active infection. The University of Louisville Infectious Diseases Laboratory accepted non-traditional specimen types, most without a paired, positive NP result, for research purposes only to support local epidemiology efforts. A real-time reverse transcription-polymerase chain reaction (RT-PCR) assay originally validated for NP specimens was used …
What? Now A Respiratory Syncytial Virus Epidemic,
2023
University of Louisville
What? Now A Respiratory Syncytial Virus Epidemic, Aya Allam, Steven B Lippmann
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Adapting International Clinical Trials During Covid-19 And Beyond,
2023
Charles Darwin University, Australia
Adapting International Clinical Trials During Covid-19 And Beyond, Kamala Thriemer, Kamala Thriemer, Mohammad Shafiul Alam, Bipin Adhikari, Rupam Tripura, Mohammad Sharif Hossain, Michael Christian, Najia Bano Ghanchi, Hellen Mnjala, Muhammad Asim
Department of Pathology and Laboratory Medicine
Background: The COVID-19 pandemic and resulting restrictions, particularly travel restrictions, have had significant impact on the conduct of global clinical trials. Our clinical trials programme, which relied on in-person visits for training, monitoring and capacity building across nine low- and middle-income countries, had to adapt to those unprecedented operational challenges. We report the adaptation of our working model with a focus on the operational areas of training, monitoring and cross-site collaboration.
The new working model: Adaptations include changing training strategies from in-person site visits with three or four team members to a multi-pronged virtual approach, with generic online training for …
Covid- 19 Reflection,
2023
Sacred Heart University
Covid- 19 Reflection, Anonymous
Community Reflections
I wrote about what was going through my head and what I want people to know about how it affected me.
My Covid Travel Experience,
2023
Sacred Heart University
My Covid Travel Experience, Anonymous
Community Reflections
When I first heard that we were all getting two weeks off from school because of some weird virus, I was really excited. I didn’t know the severity of it until two weeks turned into three weeks, and three turned into six, and then we were out for the rest of the school year. I didn’t get Covid until the very end of it. I was in Europe on Vacation with my family and I was on a cruise.
Senior Night,
2023
Sacred Heart University
Senior Night, Anonymous
Community Reflections
This content refelcts on my experience because as the world seemed to be going back to normal, COVID-19 ruined my special night of senior year in 2021 that I looked forward to since being a freshman.
Covid-19'S Impact On My Final Two Years Of High School,
2023
University of Sacred Heart
Covid-19'S Impact On My Final Two Years Of High School, Robert Bevilacqua
Community Reflections
This document primarily concerns COVID-19's impact on my final two years of high school (NY) and its repercussions on my academic career.
Covid Stress,
2023
Sacred Heart University
Covid Stress, Anonymous
Community Reflections
My COVID-19 experience was definitely something that I will never forget. At the time with me working in the healthcare field, being a CNA. It brought much stress and especially chaos. After coming home from long shifts helping with elderly patients who were sickened by covid, it definitely was hard to see and it took a toll on me.
Covid- 19,
2023
Sacred Heart University
Covid- 19, Anonymous
Community Reflections
Many aspects of our daily lives were thrown into disarray because of the COVID-19 pandemic. Even until January 2023, no one knew what true, long-term consequences it would have. It would introduce new customs that many of us had never experienced before, like wearing masks, keeping six feet apart, and not shaking each other's hands to introduce ourselves. We have not seen such an outbreak since the 1980s with HIV and AIDS in the U.S., where there was so much paranoia within our society that we were constantly sanitizing our hands and quarantining when someone was infected with COVID-19.
My Brutal Covid Experience,
2023
Sacred Heart University
My Brutal Covid Experience, Anonymous
Community Reflections
Within weeks, Covid 19 was present in the United States. It affected everyone in the world. Nobody knew what to do at the start of this, and nobody completely knew what was going on.
Covid 19 And Other Pandemics,
2023
Sacred Heart University
Covid 19 And Other Pandemics, Anonymous
Community Reflections
The Coronavirus was a global pandemic that spread from China to the United States in March 2020. In March, it was announced to us that the United States had to go into lockdown for two weeks. Little did we know that this two-week lockdown was going to turn into almost a year. This news was found to be very surprising by everyone because it has been so many years since we had a pandemic that affected everyone.
Covid Birthday,
2023
Sacred Heart University
Covid Birthday, Anonymous
Community Reflections
Covid 19 was a shock to us all. No one knew what to expect. It was a new way of living for everyone.
Family Experience,
2023
Sacred Heart University
Family Experience, Anonymous
Community Reflections
It started with whispers in the hallway. Hearing rumors from peers that we would have two weeks off from school and then return to share stories from those glorious 14 days. In hindsight, it was naïve to think that Covid-19 would have such little impact on my life, but it eventually struck my family as it did thousands of others.
My Account Of Covid- 19,
2023
Sacred Heart University, Puerto Rico
My Account Of Covid- 19, Ryan Anonymous
Community Reflections
It was March 13, 2020, when the first encounter happened. The Coronavirus was still new to many of us, so we really did not know the true severity that this virus had in store. One morning, during second period, the entire school was called down to the auditorium for an impromptu assembly. With the recent closings of neighboring schools, we were certain that we were the next to close; everyone was ecstatic.
