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Articles 58831 - 58860 of 256043

Full-Text Articles in Life Sciences

Mitigation Of Herbicide Resistance Development Among Weed Species In Cotton And Peanut, Justin S. Calhoun Dec 2021

Mitigation Of Herbicide Resistance Development Among Weed Species In Cotton And Peanut, Justin S. Calhoun

Theses and Dissertations

Herbicide resistance development among weed populations in cotton and peanut is becoming increasingly difficult to manage. If resistant populations continue to persist, weed control practices for producers will become less efficient and more costly. The objective of this research was to evaluate alternative weed control techniques designed to mitigate herbicide resistance development for their agronomic and economic impact on weed management systems. Studies were conducted in 2019, 2020, and 2021 at multiple locations in Mississippi and Arkansas investigating multiple techniques including the addition of soil surfactants in herbicide tank mixtures, increasing SOAs utilized in peanut herbicide programs, applying non-labeled herbicides …

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Soybean (Glycine Max) Response To Multiple, Sublethal Exposures Of 2,4-D And Dicamba From Vegetative Through Reproductive Growth, Graham Robert Oakley Dec 2021

Soybean (Glycine Max) Response To Multiple, Sublethal Exposures Of 2,4-D And Dicamba From Vegetative Through Reproductive Growth, Graham Robert Oakley

Theses and Dissertations

This study was conducted to determine whether soybean productivity is affected by multiple, sublethal herbicide exposures. The effects of dicamba and 2,4-D on soybean (Glycine max) productivity was investigated at 17 site-years. Relative to a single exposure of dicamba at R1, an additional exposure at either V3 or R3 reduced yield up to 23%. Three or more applications did not further decrease yields relative to an R1&R3 exposure. For 2,4-D, a single application to V3, R1, R3, or R5 soybean did not affect grain yield. However, two exposures of 2,4-D occurring from V3 through R3 reduced yield 5 to 7%. …

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The Art Of Amphibian Conservation: Linking In-Situ And Ex-Situ Populations Of Endangered Species Through Genome Banking, Isabella Joann Burger Dec 2021

The Art Of Amphibian Conservation: Linking In-Situ And Ex-Situ Populations Of Endangered Species Through Genome Banking, Isabella Joann Burger

Theses and Dissertations

Limited breeding success in captive breeding programs has necessitated the development of assisted reproductive technologies (ART) to preserve and increase genetic variation and population numbers of both captive and wild amphibian groups. ART has been shown to be successful in numerous anuran species, and current studies focus on the application of ART in ex-situ populations. The focus of this project is to show that linking in-situ and ex-situ amphibian populations through sperm cryopreservation, genome banking, and in-vitro fertilization is possible, with the goal of increasing gene diversity throughout groups in order to produce self-sustaining, wild populations in the future. Specific …

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Burning And Management Alternatives On Forage Accumulation And Floristic Composition Of A Native Pasture, I. Heringer, A. V. A. Jacques Dec 2021

Burning And Management Alternatives On Forage Accumulation And Floristic Composition Of A Native Pasture, I. Heringer, A. V. A. Jacques

IGC Proceedings (1977-2023)

The forage accumulation and floristic composition of native pasture, submitted to burning and alternative management practices, was evaluated during one year. The experimental design was a completely randomized, with five treatments and three replications. The forage accumulation was evaluated in a grazing exclusion cage, and the floristic composition was estimated with Botanal method. The systems without burning were more productive and, among these, the forage accumulation was similar between the one without burning and without mowing and the improve treatments, and the annual accumulation was greater than 9,000 Kg/ha of green forage dry matter. The species Paspalum notatum, P. …

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Nitrogen Flow To Duodenum Of Steers Grazing On Orchardgrass And Meadowfescue Pastures, Masaaki Hanada, Y. Aibibula, Meiji Okamoto Dec 2021

Nitrogen Flow To Duodenum Of Steers Grazing On Orchardgrass And Meadowfescue Pastures, Masaaki Hanada, Y. Aibibula, Meiji Okamoto

IGC Proceedings (1977-2023)

This experiment was conducted to evaluate nitrogen flow to the duodenum of steers grazing on orchardgrass (Dactylis glomerata L., OG) or meadowfescue (Festuca elatior L., MF) pasture. Holstein steers fitted with cannulas in the rumen and duodenum were used. Nitrogen content and in vitro dry matter digestibility of herbage did not differ between OG and MF pastures. Herbage nitrogen intake of steers grazing on OG and MF pastures averaged 229 and 271 g/day, respectively. Nitrogen flows to the duodenum of steers grazing on orchardgrass and meadowfescue pastures averaged 187 and 195g/d, respectively. Microbial nitrogen flow to the duodenum …

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The Effects Of Post-Grazing Sward Conditions On Herbage Accumulation In Winter And Spring, F. P. Hughes, P. N. P. Matthews, C. Matthew Dec 2021

The Effects Of Post-Grazing Sward Conditions On Herbage Accumulation In Winter And Spring, F. P. Hughes, P. N. P. Matthews, C. Matthew

IGC Proceedings (1977-2023)

Two on-farm experiments were conducted in the winter and spring of 1998 on a New Zealand seasonal production dairy farm to determine the effect of herbage mass present after grazing on subsequent pasture growth rates. Experiments involved a range of post-grazing levels of herbage mass (870, 1140, 1390, 1640, 1920 kg DM/ha in winter, and 1100, 1420, 1700 and 1910 kg DM/ha in spring) representing a range in cow intakes of 6.1-20.0 and 7.6-18.5 kg DM/cow/day in winter and spring, respectively. In both experiments there was a range of postgrazing herbage mass (1200-1600 kg DM/ha in winter and 1400-1800 kg …

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The Effects Of Various Carbon Sources And The Presence Of Vitamin B-12 On The Production Of 1,3-Propanediol By L. Reuteri., Kayden Stevenson Dec 2021

The Effects Of Various Carbon Sources And The Presence Of Vitamin B-12 On The Production Of 1,3-Propanediol By L. Reuteri., Kayden Stevenson

Fall Student Research Symposium 2021

Dairy product preservation has evolved over thousands of years and has been a major benefit to humanity by creating stable, nutrient-dense food sources. Today the lactic acid bacteria Lactobacillus reuteri is important in preserving fermented dairy products through the production of the compound reuterin. Reuterin (1,3-propanediol) demonstrates antibiotic properties that prevent the fermentation of dairy products by undesirable bacteria. The purpose of this study is to determine if L. reuteri can produce 1,3-propanediol from a variety of carbon sources. Bacterial strains were incubated in the presence of a carbon source with vitamin B-12 or without B-12 for seven days with …

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Distribution, Abundance, And Population Genetics Of The Alligator Snapping Turtle (Macrochelys Temminckii) In Mississippi, Luke Pearson Dec 2021

Distribution, Abundance, And Population Genetics Of The Alligator Snapping Turtle (Macrochelys Temminckii) In Mississippi, Luke Pearson

Dissertations

The southeastern United States is a freshwater turtle biodiversity hotspot, second only to southeastern Asia, and this region is inhabited by one of the largest freshwater turtles in the world: the alligator snapping turtle (Macrochelys temminckii). This species was heavily harvested from the 1960’s to the 1980’s for the turtle soup industry, apparently contributing to substantial, range-wide population declines. These declines, coupled with anthropogenic impacts on riverine and floodplain habitats, have led to M. temminckii being petitioned for federal listing under the U.S. Endangered Species Act; it is currently under review by the U.S. Fish and Wildlife Service …

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Granulins In Norm And Neurodegenerative Pathologies, Anukool Bhopatkar Dec 2021

Granulins In Norm And Neurodegenerative Pathologies, Anukool Bhopatkar

Dissertations

Granulins (GRNs) are small, cysteine-rich modules produced from the proteolytic cleavage of the precursor protein called progranulin (PGRN). GRNs are present in the form of seven tandem repeats within the precursor and are known to be produced in the extracellular and in lysosomal environments. In physiology, PGRN and GRNs plays pleiotropic roles such as neuronal growth and differentiation, immunomodulation, wound healing. Recent studies have implicated pathological role for PGRN in Alzheimer disease (AD) and frontotemporal dementia (FTD) but specific mechanism(s) remains unclear. However, potential interactions between GRNs and Ab42 and TDP-43 seem like a plausible underlying mechanism. Studies presented here …

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Dicer Represses Antiviral Innate Immunity Pathways In Mouse Embryonic Stem Cells, Chandan Gurung Dec 2021

Dicer Represses Antiviral Innate Immunity Pathways In Mouse Embryonic Stem Cells, Chandan Gurung

Dissertations

Recent studies have demonstrated that embryonic stem cells (ESCs) are deficient in expressing type I interferons (IFN), the cytokines that play key roles in antiviral responses. However, the underlying molecular mechanisms and biological implications of this finding are poorly understood. In this study, I used a synthetic RNA-based assay that can simultaneously assess multiple forms of antiviral responses in ESCs. Dicer is an enzyme essential for RNA interference (RNAi), which is used as a major antiviral mechanism in invertebrates but not clear in vertebrates. RNAi activity is detected in wild-type ESCs but is abolished in Dicer knockout ESCs (D−/−ESCs) as …

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Discovering Virally Encoded Proteins That Block Type Iv Crispr Immune Systems, Andrew Williams Dec 2021

Discovering Virally Encoded Proteins That Block Type Iv Crispr Immune Systems, Andrew Williams

Fall Student Research Symposium 2021

Bacteria and the viruses that infect them have been at war from the beginnings of life until today. Due to selective pressure from viral infection, bacteria have evolved various biological defense systems, including CRISPR-Cas systems that use a genetic memory of previous viral encounters to protect against future invasions. However, recently it has been shown that viruses have evolved counter-strategies to evade CRISPR systems. Virally encoded proteins called anti-CRISPRs use a variety of mechanisms to block the activity of CRISPR immune systems in order to infect bacterial cells. The Jackson lab at USU recently showed that a Type IV-A CRISPR-Cas …

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Characterization Of The Atpase Activity Of Casding, Christian Cahoon Dec 2021

Characterization Of The Atpase Activity Of Casding, Christian Cahoon

Fall Student Research Symposium 2021

The battle between bacteria and phage has been ongoing for eons. This battle has generated the evolutionary pressure necessary for the development of microbial immune systems. Characterization of these systems has led to the discovery of molecular tools such CRISPR-Cas systems. This system uses a genetic memory of past viral infections coupled with associated proteins to form ribonucleoprotein complexes which seek out and destroy foreign genetic elements. These systems have been repurposed by scientists to create powerful gene editing tools such as Cas9. With such powerful molecular tools being discovered, we have pursued the characterization of a relatively unknown system, …

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Characterizing The Mechanisms Of C. Elegans Prmt1 Temperature Dependence, Arianna Towne Dec 2021

Characterizing The Mechanisms Of C. Elegans Prmt1 Temperature Dependence, Arianna Towne

Fall Student Research Symposium 2021

Over time, cellular enzymes evolve through amino acid mutations which allow them to remain functional at temperatures specific to the host organism. This activity may be partially or completely lost when enzymes are removed from their optimal temperature range, as is observed for the C. elegans protein arginine methyltransferase 1 (cPRMT1). This construct demonstrates maximum enzymatic activity at the C. elegans optimum of 20°C, but no activity at 37°C where activity for mammalian PRMT1 variants is observed. Given dysregulation of PRMT1 has been linked to various disease states, we are interested in exploiting the biophysical mechanisms of cPRMT1 temperature dependence …

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Determining The Nucleic Acid Binding Affinities Of Crispr-Associated Ding (Casding), Matt Armbrust Dec 2021

Determining The Nucleic Acid Binding Affinities Of Crispr-Associated Ding (Casding), Matt Armbrust

Fall Student Research Symposium 2021

CRISPR-Cas systems are adaptive prokaryotic immune systems that enable host cells to defend against attack from foreign nucleic acids such as phage infections or plasmids. CRISPR-Cas systems are diverse and encompass 2 classes, 6 types, and 33 subtypes. The Type IV-A CRISPR-Cas system from Pseudomonas aeruginosa strain 83 is composed of five different genes (csf1, csf2, csf3, cas6, and dinG). Type IV-A systems are poorly understood, and currently there is little research detailing their biological and biochemical mechanism of immunity. CasDinG, an ancillary protein within the Type IV-A system, is required for an immune response in vivo. However, the role …

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True Grit (1969) And Feminism: How It Succeeds And Why We Should Expect Better, Courtney Isom Dec 2021

True Grit (1969) And Feminism: How It Succeeds And Why We Should Expect Better, Courtney Isom

Fall Student Research Symposium 2021

Hollywood Westerns are certainly not renowned for their contribution to feminist plots or characters, but True Grit (1969) is one of the more forward thinking movies with respect to women’s roles. However, the movie still portrays traditional power structures of patriarchy that undermine the female character’s autonomy. Looking at this film through the lens of both Critical Rhetoric and a Gender Diversity Perspective allows us to see the nuances of Mattie Ross' stand against oppressive traditional roles, while also examining the ways in which she is still dominated by discursive patriarchal practices. Celeste Condit’s gender diversity perspective encourages ditching traditional …

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Halotolerant Rhizosphere Bacteria: Isolation Of Rhizosphere Bacteria From Native Utah Plant Ceanothus Velutinus, Alyssa Nielsen Dec 2021

Halotolerant Rhizosphere Bacteria: Isolation Of Rhizosphere Bacteria From Native Utah Plant Ceanothus Velutinus, Alyssa Nielsen

Fall Student Research Symposium 2021

Increasing incidences of drought forced farmers to use the secondary, degraded water for irrigation. These water sources are rich in salt concentrations. This project has started with the hopes of finding bacteria from the rhizosphere of a native to Utah plant, Ceanothus velutinus, that helps the plant survive the saltier conditions of Utah. The rhizosphere, a layer of soil attached to the roots of a plant, contains microorganisms that may contribute to the plants' abiotic and biotic stress resistance. These microorganisms are known as Plant Growth Promoting Rhizobacteria (PGPR). The roots and rhizosphere samples were collected from Tony Grove in …

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Identification And Isolation Of Halotolerant Endophytes In Ceanothus Velutinus May Lead To Plant Health In Saline Conditions, Katherine Hewitt Dec 2021

Identification And Isolation Of Halotolerant Endophytes In Ceanothus Velutinus May Lead To Plant Health In Saline Conditions, Katherine Hewitt

Fall Student Research Symposium 2021

Plant-microbe relations are integral to plant survival and crop productivity. Part of a plant’s biosphere are endophytes, microbes found between the cells of a plant. Endophytes can be beneficial to help a plant cope with abiotic stressors such as salinity. In Utah, our soils are high in salinity due to topography and climate. Climate change has increased soil salinity across the world, and water availability is becoming scarcer leading agriculture to use more saline sources to irrigate. Thus, salt is a concern for farmers. We aim to identify halotolerant endophytes from Ceanothus velutinus, Snowbrush which is native to the …

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Understanding How Changes In Precipitation Intensity Will Affect Vegetation In The Western U.S., Cristina Chirvasa Dec 2021

Understanding How Changes In Precipitation Intensity Will Affect Vegetation In The Western U.S., Cristina Chirvasa

Fall Student Research Symposium 2021

Precipitation events are becoming more intense as the atmosphere warms, but it remains unclear how precipitation intensification will affect plant growth in arid and semiarid ecosystems. There is conflicting evidence suggesting that larger precipitation events may either increase or decrease plant growth. Here, we report the growth responses of herbaceous and woody plants to experimental manipulations of precipitation intensity in a cold, semi-arid ecosystem in Utah, USA. In this experiment, precipitation was collected and redeposited as fewer, larger events with total annual precipitation kept constant across treatments. Results from the first two growing seasons revealed that more intense events ‘pushed’ …

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Log Proximity And Moss As Indicators Of Conifer Seedling Abundance In Old-Growth Douglas-Fir/ Hemlock Forests, Isabella Wetzler Dec 2021

Log Proximity And Moss As Indicators Of Conifer Seedling Abundance In Old-Growth Douglas-Fir/ Hemlock Forests, Isabella Wetzler

Fall Student Research Symposium 2021

It is increasingly essential to develop a comprehensive understanding of forest processes so that we may better conserve and maintain our old-growth forests in the face of climate change. In the Pacific Northwest, logs might elevate and remove conifer seedlings from light competition with moss and herbs, but seedlings growing on the forest floor may benefit from log shade. Moss can retain moisture which may result in higher water availability for seedlings, but in droughty conditions the desiccated moss might leave seedlings ‘high and dry’. Logs increase mircrosite heterogeneity, providing cool, moist microclimates for seedlings and protecting them from droughty …

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Climate Change Impacts On Atmospheric Ammonia And Implications For Human Health, Casey Olson, Connor Snow, Bridger Jorgensen Dec 2021

Climate Change Impacts On Atmospheric Ammonia And Implications For Human Health, Casey Olson, Connor Snow, Bridger Jorgensen

Fall Student Research Symposium 2021

According to national data Cache Valley has the highest concentrations of atmospheric ammonia in the nation. This study aims to answer the questions of whether climate variables and events such as precipitation, averaged winds, geopotential height, and teleconnections can be used to predict the behavior of pollutants and how human biology is potentially affected. Data from the Utah Climate Center shows that the 3rd yearly quartile has the highest levels of airborne ammonia due to the high levels of fertilizer use and livestock emissions in the farming industry in Cache Valley. After data analysis, there seems to be a connection …

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A Method To Assess Response Inhibition During A Balance Recovery Step, Molly Rowley Dec 2021

A Method To Assess Response Inhibition During A Balance Recovery Step, Molly Rowley

Fall Student Research Symposium 2021

Background: Correlations between falls and executive function tests, particularly those tests emphasizing inhibitory control, suggests that the ability to suppress automatic, but unwanted action, is important in fall prevention. Response inhibition has been a topic of considerable interest in the cognitive neuroscience community for many decades, bringing with it, the development of techniques that could be used to inform assessment of reactive balance. Research question: Can we apply a method used in traditional cognitive testing - the stop signal task - to measure response inhibition in a speeded, balance recovery task? Methods: Twenty healthy, young adults completed a novel reactive …

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Synthetic Hagfish Slime Mimetics: Mechanical Characterization, Hayden Johns, Spencer Walker Dec 2021

Synthetic Hagfish Slime Mimetics: Mechanical Characterization, Hayden Johns, Spencer Walker

Fall Student Research Symposium 2021

Hagfish are ancient animals that eject a slime when attacked by predators. The slime that the hagfish emit is almost entirely composed of water but protein strands within the slime cause the slime to have incredible strength. However, these protein strands will be formed synthetically for the purposes of our experiment. To defend against foes, the Navy launches plastic ropes into the propellers of enemy warships in order to decrease the thrust of the motors. In a push to find a more biodegradable solution, the utilization of hagfish slime has shown great promise in stopping propellers.While we know that the …

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Estimating Cattle Density Using Wildlife Cameras, Emily Bonebrake Dec 2021

Estimating Cattle Density Using Wildlife Cameras, Emily Bonebrake

Fall Student Research Symposium 2021

Quantifying the abundance and distribution of animal populations is critical for effective wildlife research and management. Due to their cost-effectiveness, wildlife cameras have become an increasingly popular tool for estimating population densities. Previously, this technique relied on ‘capture-recapture’ models that utilized re-sightings of individually marked animals, but in recent years methods have been developed to estimate the population densities of unmarked animals. One such method is the random encounter and staying time (REST) technique, which does this by assuming that the cumulative time animals stay within the view of the camera scales linearly with the number of individuals. This allows …

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Universal Healthcare: Is It The Future?, Izzy Wappett Dec 2021

Universal Healthcare: Is It The Future?, Izzy Wappett

Fall Student Research Symposium 2021

About 8.5% of the United States population has no form of healthcare. The rest of the population either has a form of public or private insurance given to them by the government, private insurers, or employers. But there are countries worldwide that have systems where every citizen has healthcare. This is called universal healthcare. Universal Healthcare has shown to be more effective because it portrays healthcare as less of a privilege and more of a right to all. But many Americans view this kind of system as controlling and a system that takes away your freedom. But as studies and …

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Effect Of Basal Diet And Black Raspberry Supplementation On Gene Biomarkers Of "Leaky Gut" In Mouse Model Of Colitis-Associated Colorectal Cancer, Eliza Stewart Dec 2021

Effect Of Basal Diet And Black Raspberry Supplementation On Gene Biomarkers Of "Leaky Gut" In Mouse Model Of Colitis-Associated Colorectal Cancer, Eliza Stewart

Fall Student Research Symposium 2021

Colorectal cancer is currently the third leading cause of cancer death in the world. The risk of developing colorectal cancer increases significantly in individuals who suffer from colitis, which is inflammation of the colon lining, seen in Irritable Bowel Disease. The term “leaky gut” is often used to describe increased intestinal permeability and is closely related to colitis. Leaky gut is associated with dysbiosis of the gut microbiota, which can occur through diet. This dysbiosis leads to pro-longed inflammation and affects genes that encode for proteins involved in the tight junctions between cells. Compromised intestinal integrity allows for translocation of …

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Digitization Of Entomological Collections At Usu, Eastern Using Scan (Symbiota Collections Of Arthropods Network) Data Portal And Seek! Inaturalist App, Alexandra Cartwright Dec 2021

Digitization Of Entomological Collections At Usu, Eastern Using Scan (Symbiota Collections Of Arthropods Network) Data Portal And Seek! Inaturalist App, Alexandra Cartwright

Fall Student Research Symposium 2021

Pollinators, including bees, provide valuable ecosystem services for native plants and agricultural species. Phenology, or the timing of biological events such as flowering of plants, is changing as a result of climate change. The digitization of specimens allows for insights into species distributions, seasonality, and phenology in 60-70-year-old collections. The entomological collection at Utah State University, Eastern houses approximately 3,000 individual specimens and over 100 bees. The oldest specimens date from 1953, many from the 1960s, 70s, & 80s and the majority of specimens are from Carbon and Emery Counties. Digitization of entomological collections can provide: species distributions: Which species …

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Responses Of Benthic Calcifying Algae To Ocean Acidification Differ Between Laboratory And Field Settings, Heather N. Page, Keisha D. Bahr, Tyler Cyronak, Elizabeth B. Jewett, Maggie D. Johnson, Sophie J. Mccoy Dec 2021

Responses Of Benthic Calcifying Algae To Ocean Acidification Differ Between Laboratory And Field Settings, Heather N. Page, Keisha D. Bahr, Tyler Cyronak, Elizabeth B. Jewett, Maggie D. Johnson, Sophie J. Mccoy

Marine & Environmental Sciences Faculty Articles

Accurately predicting the effects of ocean and coastal acidification on marine ecosystems requires understanding how responses scale from laboratory experiments to the natural world. Using benthic calcifying macroalgae as a model system, we performed a semi-quantitative synthesis to compare directional responses between laboratory experiments and field studies. Variability in ecological, spatial, and temporal scales across studies, and the disparity in the number of responses documented in laboratory and field settings, make direct comparisons difficult. Despite these differences, some responses, including community-level measurements, were consistent across laboratory and field studies. However, there were also mismatches in the directionality of many responses …

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Determination Of Free Fatty Acid And Triglyceride Fatty Acid Of Food Fats Using A Rapid Gas Chromatographic Method, Aubreyona Migliori Dec 2021

Determination Of Free Fatty Acid And Triglyceride Fatty Acid Of Food Fats Using A Rapid Gas Chromatographic Method, Aubreyona Migliori

Fall Student Research Symposium 2021

Food fats are primarily triglycerides composed of esterified fatty acids on a glycerol backbone. To measure the fatty acid content of foods, a derivatization reaction is conducted which transfers the fatty acids from glycerol to methanol, forming a fatty acid methyl ester (FAME). FAMES are measured using gas chromatography with flame ionization detection (GC-FID). Free fatty acids in foods are a result of a degradation reactions and are considered a defect. This decreases consumer acceptance and expedites further deterioration which decreases the value of edible oils. The goal of this study was to develop a rapid and sensitive method to …

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Inhibition Of Viral Membrane Fusion By Peptides And Approaches To Peptide Design, Nejat Düzgüneş, Narcis Fernandez-Fuentes, Krystyna Konopka Dec 2021

Inhibition Of Viral Membrane Fusion By Peptides And Approaches To Peptide Design, Nejat Düzgüneş, Narcis Fernandez-Fuentes, Krystyna Konopka

Pacific Faculty Work

Fusion of lipid-enveloped viruses with the cellular plasma membrane or the endosome membrane is mediated by viral envelope proteins that undergo large conformational changes following binding to receptors. The HIV-1 fusion protein gp41 undergoes a transition into a “six-helix bundle” after binding of the surface protein gp120 to the CD4 receptor and a co-receptor. Synthetic peptides that mimic part of this structure interfere with the formation of the helix structure and inhibit membrane fusion. This approach also works with the S spike protein of SARS-CoV-2. Here we review the peptide inhibitors of membrane fusion involved in infection by influenza virus, …

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The Price Of Surviving On Adrenaline: Developmental Programming Responses To Chronic Fetal Hypercatecholaminemia Contribute To Poor Muscle Growth Capacity And Metabolic Dysfunction In Iugr-Born Offspring, Rachel L. Gibbs, Dustin T. Yates Dec 2021

The Price Of Surviving On Adrenaline: Developmental Programming Responses To Chronic Fetal Hypercatecholaminemia Contribute To Poor Muscle Growth Capacity And Metabolic Dysfunction In Iugr-Born Offspring, Rachel L. Gibbs, Dustin T. Yates

Department of Animal Science: Faculty Publications

Maternofetal stress induces fetal programming that restricts skeletal muscle growth capacity and metabolic function, resulting in intrauterine growth restriction (IUGR) of the fetus. This thrifty phenotype aids fetal survival but also yields reduced muscle mass and metabolic dysfunction after birth. Consequently, IUGR-born individuals are at greater lifelong risk for metabolic disorders that reduce quality of life. In livestock, IUGR-born animals exhibit poor growth efficiency and body composition, making these animals more costly and less valuable. Specifically, IUGR-associated programming causes a greater propensity for fat deposition and a reduced capacity for muscle accretion. This, combined with metabolic inefficiency, means that these …

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