Life Sciences Commons^™

Abiotic Disorders Of Tomatoes, Nick Volesky, Marion Murray, Sheriden M. Hansen, Maegen A. Lewis

All Current Publications

Monitoring tomato plants regularly from seedling to harvest allows for early detection of abnormal conditions. Although tomato plants can be attacked by a variety of living organisms (insects, mites, pathogens, vertebrates), nonliving (abiotic) conditions can cause just as much damage. Abiotic diseases in tomato plants can arise from nutrient deficiencies, temperature extremes, abnormal lighting, chemical application, changes in water uptake, mechanical damage, genetic mutations, and more. This guide will cover most of the abiotic disorders and diseases that can affect tomatoes in Utah.

Patient Knowledge Of Family History Of Cardiac Events And Risk Factors: Potential For Increase In Preventative Care Of Cardiovascular Diseases, Joseph Marentette

Honors Theses

The following literature review regards the preventative care of cardiovascular disease (CVD) patients with the knowledge of familial cardiac events and personal cardiac risk factors, particularly in younger populations ranging from ages 18 to 39, and develop potential preventative care measures. CVD is preventable with early reduction of risk factors. People can lower the impact of cardiac risk factors through the modification of their current lifestyle and behavioral habits. However, this is limited to the education and motivation of the person. Primary emphasis must be placed on community education and physician-patient interactions regarding CVD and cardiac risk factors. Physicians need …

Isolation And Characterization Of Potential Lactic Acid Producing Bacteria From Fermented Fruit Juice, Than Wah Wah, Maw Saw Sandar, Htun Reemon

ASEAN Journal on Science and Technology for Development

Lactobacillus species are used as probiotics to inhibit human pathogens because of their ability to produce antimicrobial substances. However, when different kinds of antibiotics are used, the antibiotic resistance of drug-resistant bacteria increases. In this study, lactic acid-producing bacteria with antimicrobial activity were isolated and used as probiotics to inhibit six human pathogens, namely Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Bacillus cereus, Salmonella typhi, and Shigella boydii. Nine bacterial isolates were obtained from the crude juice of sugar cane (Saccharum officinarum), strawberry (Fragaria ananassa), and fruit pulp of palm (Borassus flabellifer). Among them, three bacterial isolates (S1, SC, and PP) …

Regulatory Amendments Of The Strategic Policy For The Job Creation In Indonesia: Research And Innovation Aspect, Putera Prakoso Bhairawa, Widianingsih Ida, Ningrum Sinta, Suryanto, Rianto Yan

ASEAN Journal on Science and Technology for Development

The Job Creation Law, enacted in Indonesia in November 2020, has provided a new understanding of the sectors, such as investment and business activities, employment, and ease of conducting business, that are directly related to various aspects of regulatory adjustment. Research and innovation related to regulatory adjustments have received growing attention in recent years. This article thus attempts to reveal regulatory amendments from the strategic policy of job creation, particularly in terms of research and innovation, grouped into four topics: 1) conducting research and innovation activities; 2) supporting human resources and expertise; 3) stipulating policy support for facilitation, licensing, and …

Coastal Vulnerability Assessment For Community Resilience On Abrasion: Case Of Bugel Coast, Kulon Progo Regency, Indonesia, Ramadhan Cahyadi, Dina Ruslanjari, Diana Puspitasari, Gading Dita Indasari, Naufal Sandro

ASEAN Journal on Science and Technology for Development

The coastal boundary can be optimized for settlement and agriculture site based on a spatial plan for Kulon Progo Regency 2012–2032 within a minimum distance of 100m from the coastline. The location of ring 1 local transmigration settlement on the Bugel Coast is less than 100 m. The increasing trend in coastal erosion caused by climate change is a major contributing factor to the reduction of coastal borders. Thus, rapid assessment of coastal erosion vulnerability is necessary to determine an effective coastal management response. This paper aims to analyze the coastal erosion level using vulnerability assessment, geomorphology of coastal areas, …

Grand Design For Merapi Irrigation Channel System Using Watershed And River Region Approaches Based On Community Development In Yogyakarta, Indonesia, Suprayogi Slamet, Gunawan Totok, Murti Sigit Heru, Prihantarto Wikan Jaya, Alatas Masrur

ASEAN Journal on Science and Technology for Development

This paper proposes a grand design for Merapi Irrigation Channel, an irrigation channel system spanning from Turi to Cangkringan District in Yogyakarta, Indonesia. This design is based on Geographic Information System research to assess the feasibility of the system from two aspects, namely geophysics using site selection approaches (watershed and river region) and community aspirations, analyze potential water resource availability to support its sustainability, and construct a grand design. Primary data acquired from IKONOS image interpretation were used to collect geophysical and ?eld data for parameter mapping, and spatial data were modeled using Geographic Information System technology to determine paths, …

Healthy Eating At Providence College, Katelyn Breen, Alexis Carabetta, Lilah Milton, Katharine Shaughnessy

School of Business Student Scholarship

Katelyn Breen ’24, Major: Marketing

Alexis Carabetta ’24, Major: Marketing

Lilah Milton ’24, Major: Marketing

Katharine Shaughnessy ’24, Major: Marketing

Faculty Mentor: Dr. Kevin Newman, Marketing

Our marketing group surveyed 100 Providence College students about their healthy eating choices and level of satisfaction of Ray Dining Hall’s healthy eating options. From the data collected, we discovered most students are unsatisfied with Ray Dining Hall and they suggested the need for a greater variety of healthy eating options. Based on this information, our group put together three recommendations that Providence College Dining should implement: 1) provide students with healthy eating instructions; …

Targeting Cd123 In Blastic Plasmacytoid Dendritic Cell Neoplasm Using Allogeneic Anti-Cd123 Car T Cells, Tianyu Cai, Agnès Gouble, Kathryn L Black, Anna Skwarska, Ammar S Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S Neelapu, Andrew A Lane, Hagop Kantarjian, Monica L Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva

Faculty, Staff and Student Publications

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with poor outcomes with conventional therapy. Nearly 100% of BPDCNs overexpress interleukin 3 receptor subunit alpha (CD123). Given that CD123 is differentially expressed on the surface of BPDCN cells, it has emerged as an attractive therapeutic target. UCART123 is an investigational product consisting of allogeneic T cells expressing an anti-CD123 chimeric antigen receptor (CAR), edited with TALEN

Dance Of The Golgi: Understanding Golgi Dynamics In Cancer Metastasis, Rakhee Bajaj, Amanda N Warner, Jared F Fradette, Don L Gibbons

Faculty, Staff and Student Publications

The Golgi apparatus is at the center of protein processing and trafficking in normal cells. Under pathological conditions, such as in cancer, aberrant Golgi dynamics alter the tumor microenvironment and the immune landscape, which enhances the invasive and metastatic potential of cancer cells. Among these changes in the Golgi in cancer include altered Golgi orientation and morphology that contribute to atypical Golgi function in protein trafficking, post-translational modification, and exocytosis. Golgi-associated gene mutations are ubiquitous across most cancers and are responsible for modifying Golgi function to become pro-metastatic. The pharmacological targeting of the Golgi or its associated genes has been …

Agricultural Intensification Can Help Protect The Amazon Forest And Reduce Global Warming / Protecting The Amazon Forest And Reducing Global Warming Via Agricultural Intensification, Fabio R. Marin, Alencar J. Zanon, Juan P. Monzon, José F. Andrade, Evandro H.F.M. Silva, Gean L. Richter, Luis A.S. Antolin, Bruna S.M.R. Ribeiro, Giovanna G. Ribas, Rafael Battisti, Alexandre B. Heinemann, Patricio Grassini

Department of Agronomy and Horticulture: Faculty Publications

The Amazon basin includes 550 M ha covered with rainforests, with 60% of this area being in Brazil. Conversion of rainforest for soybean production raises concerns about the degree to which Brazil can reconcile production and environmental goals. Here we investigated the degree to which intensification could help Brazil produce more soybean without further encroachment of the Amazon Forest. Our analysis shows that continuation of current trends in soybean yield and area would lead to conversion of additional 5.7 M ha of forests and savannas during the next 15 years, with an associated 2550 Mt of CO2eq released into the …

Synaptic Composition Of Glutamate Receptors In A Mouse Model For Autism Spectrum Disorder, Skylar A. Anthony

Harriet L Wilkes Honors College Theses 2020 - Present

TBR1 is a high-confidence risk gene for autism spectrum disorder (ASD). Haploinsufficient (Tbr1+/-) mice exhibit ASD-characteristic behavioral changes that are often associated with amygdala circuit dysfunction. We investigated excitatory synaptic transmission in the thalamic-lateral amygdala pathway of these mice. Preliminary data showed increased AMPA receptor-mediated synaptic current in 4-week-old Tbr1+/- mice. To examine the molecular basis for this change, we measured the quantity, proportion, and density of synaptic AMPARs and NMDARs in both Tbr1+/- and wild type mice using freeze-fracture replica immunogold labeling. Receptor quantification and synaptic area demarcation were performed using supervised deep-learning networks. Our results showed no significant …

Deepening Knowledge Of Nutrient Dynamics In Coastal Waters, Meirinawati Hanny, Wahyudi A'An Johan

ASEAN Journal on Science and Technology for Development

Nutrients are important compounds in waterbodies that regulate primary productivity and phytoplankton growth, the basis of food webs. Increased nutrient concentration has become a serious concern because it causes eutrophication and threatens the sustainability of ecosystems. Eutrophication is the process of nutrient enrichment in water bodies that affects their productivity and decreases water quality. Although information about nutrient distribution, limiting nutrients, and nutrient budgets is important for coastal water management, studies of wide-scale nutrient dynamics in Indonesian waters remain limited. To provide comprehensive data on nutrients, this review summarized the concentrations and compositions of nutrients in coastal waters, compared the …

Characterization Of Large-Scale Functional Network Organization In The Human Hippocampus, Annie Zheng

Arts & Sciences Graduate Student Theses and Dissertations

The hippocampus is critically important for a diverse range of neural processes, such as episodic memory, prospective memory, affective processing, and spatial navigation. Using both individual-specific precision functional mapping and large-sample group-averaged approaches of characterizing large-scale functional network organization in the human hippocampus, we uncovered general principles of and behaviorally-associated individual differences in hippocampal organization across development in children and adults. We found the hippocampus to be modularly organized along the anterior-posterior axis with the anterior hippocampus being preferentially connected to the default mode network (DMN), as expected. However, the posterior hippocampus was strongly connected to the parietal memory network …

Author Correction: Short Amylin Receptor Antagonist Peptides Improve Memory Deficits In Alzheimer’S Disease Mouse Model, Rania Soudy, Ryoichi Kimura, Aarti Patel, Wen Fu, Kamaljit Kaur, David Westaway, Jing Yang, Jack Jhamandas

Pharmacy Faculty Articles and Research

Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-47255-9, published online 29 July 2019

The original Article contained an error in Figure 1A where the control trace for both the HEK-AMY3 and HEKWT cells was duplicated...

The original Article has been corrected.

Benefits Of, Barriers To, And Needs For An Artificial Intelligence-Powered Medication Information Voice Chatbot For Older Adults: Interview Study With Geriatrics Experts, Meghana Gudala, Mary Ellen Trail Ross, Sunitha Mogalla, Mandi Lyons, Padmavathy Ramaswamy, Kirk Roberts

Faculty, Staff and Student Publications

BACKGROUND: One of the most complicated medical needs of older adults is managing their complex medication regimens. However, the use of technology to aid older adults in this endeavor is impeded by the fact that their technological capabilities are lower than those of much of the rest of the population. What is needed to help manage medications is a technology that seamlessly integrates within their comfort levels, such as artificial intelligence agents.

OBJECTIVE: This study aimed to assess the benefits, barriers, and information needs that can be provided by an artificial intelligence-powered medication information voice chatbot for older adults.

METHODS: …

Covid Susceptibility And Severity Correlation With The Ace2 Gene, Natalie Taylor

Thinking Matters Symposium

A wide spectrum of susceptibility and severity of infection has been observed among COVID-19 patients. While some individuals remain unaffected by the Sars-Cov-2 virus, others have contracted the virus multiple times with varying levels of severity. This poster reviews some of the research demonstrating a link between the susceptibility of the Sars-Cov- 2 virus and the severity of infection, and a specific gene called ACE2. The ACE2 gene encodes an angiotensin-converting enzyme that acts as a functional receptor for the spike glycoprotein receptor binding domain of the coronavirus and severe acute respiratory syndrome coronaviruses. ACE2 presents numerous amino acid variants …

2021-2022 Program And Abstracts: Celebration Of Student Scholarship, Morehead State University. Undergraduate Research Fellowship Program.

2022 Celebration of Student Scholarship - Poster Presentations

The 2021-2022 Program and Abstracts for the Celebration of Student Scholarship at Morehead State University held on April 27, 2022. A Showcase of Student Research, Scholarship, Creative Work, and Performance Arts.

Drivers Of Macroinvertebrate Community Integrity Within Mixed Urban And Agricultural Dominated Mississippi Tributary Watersheds, Matthew R. Straus, Bethany Mabel Lian Schorr, Kevin Geedey, Michael Reisner, Benjamin Ford

Biology: Student Scholarship & Creative Works

The “urban stream syndrome” refers to a multitude of impacts caused by urbanization including flashier hydrograph, elevated concentrations of nutrients and contaminants, altered channel morphology and stability, reduced biotic richness, with increased dominance of tolerant species, reduced base flow and increased suspended solids. The drivers of these “symptoms” include impervious surfaces, piping in stormwater drainages, habitat and forest loss, water supply and sewer leaking, and direct alterations to channel morphology and flow. The goal of this study was to assess the integrity of the macroinvertebrate community and determine the most significant drivers of such integrity at the catchment, riparian zone, …

Investigation Of Cotinine Concentration Found In Saliva Of Smokers And Vapers In Demographic Sectors, Seth A. Sims

Honors Theses

A simple and reproducible method for investigation of cotinine and nicotine levels in saliva was developed by utilizing gas chromatography mass spectrometry (GCMS) and simple extraction techniques. This method allowed for accurate detection of cotinine in saliva samples collected within a 50-mile radius of Searcy, AR. The observed cotinine levels proportionately depict nicotine levels, which were then compared with participants’ demographics, displaying trends among different communities. This research hopes to provide insight into vaping popularity as well as a reproducible method that future research can utilize.

New State Records For 33 Species Of Nearctic False Click Beetles (Coleoptera: Eucnemidae), Robert L. Otto

Insecta Mundi

New state records for 33 species of Eucnemidae (Coleoptera) are reported from the eastern United States based on the examination and identifications of specimens from four institutional and personal collections over the past several years. Images of 12 eucnemid species are also provided.

Recently, opportunities were presented to identify more than 880 Eucnemidae from four institutional and personal collections. Most of the specimens came from the Carnegie Museum of Natural History and were collected during the national bark beetle surveys conducted by the United States Department of Agriculture. The survey has been instrumental in providing more state records of Eucnemidae …

The Relationship Between Circadian Rhythms And Neurodegenerative Disease, Christopher Simpson

Honors Projects

Neurodegenerative disease is a pervasive and insidious disease affecting a large proportion of the elderly population. Leading to the degeneration of neural tissue throughout the nervous system, it is a slow and progressive disorder. Because of its nature, it is possible that it has a connection to circadian rhythms. Circadian rhythms are the endogenous approximately 24-hour rhythms of the body commonly associated with the sleep-wake cycle, but they account for much more. This review aims to ascertain the relationship between the two by covering several facets of research pursued in the past five years. Beginning with establishing a basic understanding …

Quantification Of Organic Carbon Sequestered By Biogenic Iron Sulfide Minerals In Long-Term Anoxic Laboratory Incubations, Nader Nabeh, Cheyenne Brokaw, Aude Picard

Life Sciences Faculty Research

Organic carbon sequestration in sedimentary environments controls oxygen and carbon dioxide concentrations in the atmosphere. While minerals play an important role in the preservation of organic carbon, there is a lack of understanding about the formation and stability of organo-mineral interactions in anoxic environments, especially those involving authigenic iron sulfide minerals. In this study, we quantified organic carbon and nitrogen sequestered in biogenic iron sulfide minerals co-precipitated with sulfate-reducing bacteria (SRB) in freshwater and marine conditions in long-term laboratory experiments. The amounts of C and N associated with biogenic iron sulfide minerals increased with increasing cell biomass concentrations available in …

Making Better Farm Management Decisions, Matthew Stockton

Cornhusker Economics

Traditionally, producer education efforts around farm management are directed at understanding the academic topics of business operations and management including, accounting, law, human resources, marketing, production, risk, finance, etc. The information, techniques and tools taught are often concrete and focus on measurement, analysis, and data. For instance, a traditional grain marketing education program would generally include topics in forward contracts, options, futures, hedge to arrive, basis contracts, storage, and seasonality. While these programs can be quite powerful in developing quantitative skills and knowledge, they neglect a key element needed by all farm managers to make objectively clear decisions. This key …

A Patient-Derived Ipsc Model To Study Glutamate Deficiency By Shank-3 Mutation In Autism Spectrum Disorder, Tiffany Berry, Courtney Caccia

Biology Student Scholarship

Tiffany Berry ’22, Majors: Biology and Psychology

Courtney Caccia ’22, Majors: Biology and Psychology

Faculty Mentor: Dr. Charles Toth, Biology

The use of human stem cell lines derived from persons with Autism Spectrum Disorder (ASD) provides a unique opportunity to model brain growth and potential to regain brain activity for treatment. Our lab has previously used stem cells to derive 3D cardiomyocytes to examine cardiovascular disease as well as kidney organoids and macrophages to study kidney disease. Using techniques our lab has learned using these stem cell models have prepared us to examine cell communication in mutated neurons. We will …

Rare Elfin Abundance Correlates With Host Plant Density, Matthew Look

Biology Student Scholarship

Matthew Look ’22
Major: Environmental Biology
Faculty Mentor: Dr. Rachael Bonoan, Biology

The rare frosted elfin butterfly (Callophrys irus) is a host plant specialist; it lays eggs on only two plant species, including small yellow indigo (Baptisia tinctoria). This makes the butterfly especially vulnerable to habitat fragmentation. Using indigo samples and butterfly survey data, we examined the effect of indigo quantity and quality on elfin abundance at Gavins Pond (Sharon/Foxboro, MA). Indigo density significantly affected butterfly count—frosted elfins were more likely to be spotted in patches with high indigo density. While nutritional analysis is ongoing, current findings suggest that augmenting …

Hybrid Incompatibilities In Metrosideros, Jacyln Martinez

Undergraduate Research Symposium Podium Presentations

Prediction: Postzygotic reproductive isolating barriers, relating to hybrid incompatibilities are contributing to the speciation of Metrosideros

Recognition Memory For Auditory And Visual Objects, Sharica Lee, Alexa Salomon, Kevin Mohawk, Laura Werner

Undergraduate Research Symposium Posters

Visual object memory is superior to auditory object memory. Our past research showed that auditory memory was less sensitive to divide attention during study, which may be attributable to representational differences between auditory memory and visual memory.

In the present study, we attempted to equate auditory and visual memory representations in order to adequately investigate the impact of dividing attention on recognition memory.

Recognition memory is thought to rely on two distinct processes, recollection and familiarity. Recollection involves the retrieval of precise qualitative detail and is the most sensitive to dividing attention.

Infants' Intermodal Knowledge Of Gender Using Faces And Voices, Bijoux Cheun, Christina Saliba, Alexis Rice, Marian Espina

Undergraduate Research Symposium Posters

Infants begin to use intermodal knowledge to match male and female faces to the corresponding voice, in their first year of life.

Infants have more experience with female faces which should lead to greater intermodal knowledge of female faces.

Previous studies have found inconsistent results. This could be due to the type of stimuli used.

This study uses several pairs of static and dynamic faces to investigate how methodological differences may impact infants' performance.

Palm Oil And Exported Deforestation, Anja Marcusiu, Alexis Osorio

Undergraduate Research Symposium Posters

Palm oil is used in our everyday lives through: Beautify/hygiene products; Bioenergy; Food. Indonesia and Malaysia account for 85% of the world's palm oil production, making them the largest exporters. Because palm oil is a highly productive crop and is in high demand, how do companies integrate sustainability to limit deforestation and preserve biodiversity?

Identification Of Lipid Species: Potential Biomarkers For Early Detection Of Hepatocellular Carcinoma, Kit Yee Leung, Kaylee Freitas

Undergraduate Research Symposium Posters

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is associated with cirrhosis. Poor survival rate of HCC is due to diagnosis of HCC at late stage.